P:Substantia gelatinosa neuron

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Pain Term
Category Anatomy
Synonyms Substantia Gelatinosa Neurons
Pain Specific No
Documents 93
Hot Single Events 43
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Substantia gelatinosa neuron. They are ordered first by their pain relevance and then by number of times they were reported for Substantia gelatinosa neuron. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT162250 Binding of TRPV1 and Grm5 1 0.01 0.8 1.03 95.36
2 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86 78.16
3 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86 77.84
4 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 75.00
5 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 75.00
6 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 75.00
7 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13 50.00
8 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
9 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
10 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58 5.00
11 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
12 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39 5.00
13 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
14 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36 5.00
15 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35 5.00
16 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34 5.00
17 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31 5.00
18 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
19 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
20 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
21 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
22 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
23 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
24 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
25 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
26 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
27 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
28 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
29 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71 5.00
30 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
31 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
32 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
33 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
34 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
35 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
36 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64 5.00
37 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
38 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
39 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
40 INT201378 Bdnf Regulation of Gene_expression of Ltp 1 0.00 0.21 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Substantia gelatinosa neuron. They are ordered first by their pain relevance and then by number of times they were reported in Substantia gelatinosa neuron. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
2 INT2212 Binding of Abat 89 0.48 18.36 63.99 100.00
3 INT9578 Regulation of Binding of Adarb1 4 0.09 0.21 3.37 100.00
4 INT59248 Positive_regulation of Localization of Pla2g1b 4 0.47 2.27 1.81 99.92
5 INT17826 Positive_regulation of Pla2g1b 39 0.70 11.35 10.97 99.92
6 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 99.84
7 INT59245 Localization of Pla2g1b 10 0.75 4.72 2.76 99.70
8 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 99.68
9 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84 99.54
10 INT1396 Binding of Penk 355 0.48 22.79 269.65 98.52
11 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 98.38
12 INT79360 Negative_regulation of Ptafr 6 0.36 4.15 2.77 98.36
13 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4 98.28
14 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32 98.10
15 INT145550 Phosphorylation of Ptafr 1 0.52 1.03 1.28 98.04
16 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 97.98
17 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 97.72
18 INT97847 Regulation of Ptafr 3 0.43 5.41 4.64 97.68
19 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 97.56
20 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18 97.56
21 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91 97.44
22 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 97.24
23 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 97.08
24 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 96.06
25 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82 96.06
26 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 95.56
27 INT6357 Positive_regulation of Localization of Gabrg1 53 0.41 7.03 39.21 95.24
28 INT58170 Regulation of Kcne1 4 0.18 0 2.19 94.40
29 INT60865 Gene_expression of G2e3 20 0.73 2.1 12.76 93.76
30 INT79100 Regulation of Alas2 1 0.01 0 0.67 93.44
31 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 93.40
32 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72 93.16
33 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2 91.56
34 INT71628 Localization of Odf2l 1 0.03 0.09 0.75 90.32
35 INT7665 Negative_regulation of Npy1r 10 0.45 2.87 6.73 89.00
36 INT120576 Negative_regulation of Negative_regulation of Npy1r 1 0.20 0.29 1.2 89.00
37 INT66417 Localization of Pnoc 34 0.80 1.61 24.48 87.44
38 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19 83.92
39 INT129507 Regulation of Positive_regulation of Pla2g1b 1 0.42 0.1 0.22 83.76
40 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 82.32
41 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 82.24
42 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17 82.24
43 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68 81.12
44 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 78.16
45 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 77.84
46 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28 77.84
47 INT94650 Gene_expression of Grm5 32 0.77 11.26 14.82 77.04
48 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 75.00
49 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 75.00
50 INT1004 Regulation of Sst 140 0.62 18.52 94.84 75.00
51 INT163217 Transcription of Sstr2 5 0.67 0.62 5.42 75.00
52 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 75.00
53 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28 75.00
54 INT135088 Negative_regulation of Phax 15 0.36 8.93 8.29 75.00
55 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99 75.00
56 INT7725 Positive_regulation of Hgf 9 0.67 3.62 4.25 75.00
57 INT49702 Negative_regulation of Negative_regulation of Grip2 9 0.43 1.77 3.54 75.00
58 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01 75.00
59 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 75.00
60 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 75.00
61 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 75.00
62 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 75.00
63 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 75.00
64 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 75.00
65 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 75.00
66 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 75.00
67 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 75.00
68 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 75.00
69 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37 75.00
70 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 75.00
71 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06 75.00
72 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 75.00
73 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 75.00
74 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 75.00
75 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63 75.00
76 INT76428 Gene_expression of Sstr2 24 0.76 6.09 12.32 75.00
77 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25 75.00
78 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36 75.00
79 INT126484 Localization of Trpa1 15 0.80 4.08 6.64 75.00
80 INT50705 Localization of Phax 9 0.44 4.65 6.53 75.00
81 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63 75.00
82 INT21465 Positive_regulation of Epha1 5 0.48 0.69 4.4 75.00
83 INT58433 Negative_regulation of F2r 9 0.59 2.77 3.08 75.00
84 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56 75.00
85 INT52868 Negative_regulation of Pomgnt1 3 0.33 1.57 2.52 75.00
86 INT9200 Gene_expression of ITPA 8 0.65 0.86 2.18 75.00
87 INT34287 Regulation of Positive_regulation of Adarb1 3 0.10 0.47 1.8 75.00
88 INT163216 Regulation of Transcription of Sstr2 2 0.42 0.17 1.48 75.00
89 INT79099 Negative_regulation of Positive_regulation of Gtpbp4 4 0.20 0.06 1.31 75.00
90 INT163176 Regulation of Localization of Phax 1 0.24 0 0.96 75.00
91 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 72.96
92 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 72.60
93 INT147000 Localization of Plaur 2 0.78 1.29 1.86 68.92
94 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 66.40
95 INT343624 Positive_regulation of Aasdh 2 0.04 0.16 1.34 65.92
96 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 61.20
97 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 59.92
98 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 50.00
99 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 50.00
100 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 50.00
101 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 50.00
102 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 50.00
103 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77 50.00
104 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 50.00
105 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 50.00
106 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 50.00
107 INT6385 Regulation of Man2a2 48 0.61 7.8 24.68 50.00
108 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 50.00
109 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 50.00
110 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56 50.00
111 INT25745 Regulation of Tspo 6 0.45 0.25 3.1 50.00
112 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04 50.00
113 INT205190 Localization of Sec22b 8 0.09 2.36 1.48 50.00
114 INT24006 Gene_expression of Mpz 2 0.67 0.57 0.83 50.00
115 INT114911 Positive_regulation of Mpz 3 0.23 1.46 0.8 50.00
116 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55 50.00
117 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55 50.00
118 INT353894 Positive_regulation of Gene_expression of Mpz 1 0.23 0.28 0.54 50.00
119 INT353895 Negative_regulation of Mpz 1 0.19 0.48 0.4 50.00
120 INT128387 Binding of Mpz 2 0.17 0 0.18 50.00
121 INT353892 Localization of Bcl2l11 1 0.22 0.4 0.13 50.00
122 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 49.28
123 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 46.76
124 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86 46.36
125 INT38189 Regulation of Svs4 6 0.24 2.68 3.35 46.36
126 INT215595 Regulation of P2ry6 1 0.22 1.4 1.12 46.36
127 INT216650 Regulation of P2ry4 1 0.14 0.69 0.62 46.36
128 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22 43.76
129 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 42.48
130 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67 37.44
131 INT71441 Positive_regulation of Pars2 12 0.69 5.75 4.13 37.36
132 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 35.68
133 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68 31.76
134 INT61636 Positive_regulation of Positive_regulation of P2ry2 4 0.34 0.13 1.4 31.76
135 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63 31.04
136 INT57192 Binding of Ltp 43 0.41 17.48 24.96 13.44
137 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 13.44
138 INT139128 Positive_regulation of Negative_regulation of Ltp 12 0.42 4.94 15.52 11.84
139 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 10.20
140 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95 10.20
141 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 9.72
142 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91 9.72
143 INT19799 Binding of Ca2 71 0.48 13.69 12.92 8.48
144 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
145 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 5.00
146 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
147 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 5.00
148 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 5.00
149 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 5.00
150 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
151 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 5.00
152 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 5.00
153 INT5008 Localization of Calca 204 0.81 80.35 125.16 5.00
154 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 5.00
155 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
156 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 5.00
157 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
158 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 5.00
159 INT4822 Localization of Ca2 417 0.80 99.57 96.45 5.00
160 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
161 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
162 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 5.00
163 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 5.00
164 INT8534 Localization of Pax3 85 0.59 28.71 82.82 5.00
165 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
166 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 5.00
167 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 5.00
168 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 5.00
169 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 5.00
170 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 5.00
171 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 5.00
172 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
173 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 5.00
174 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 5.00
175 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 5.00
176 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 5.00
177 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
178 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 5.00
179 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 5.00
180 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7 5.00
181 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79 5.00
182 INT8690 Localization of Tac1 71 0.80 22.98 50.75 5.00
183 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 5.00
184 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
185 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 5.00
186 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 5.00
187 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 5.00
188 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04 5.00
189 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 5.00
190 INT20210 Localization of Ngf 69 0.79 46.22 38.57 5.00
191 INT13501 Binding of Drd2 65 0.48 23.76 35.6 5.00
192 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 5.00
193 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 5.00
194 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19 5.00
195 INT23222 Binding of Phax 52 0.31 7.61 30.4 5.00
196 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
197 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97 5.00
198 INT111359 Localization of Cnr1 55 0.81 11.25 27.41 5.00
199 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 5.00
200 INT54467 Localization of Ltp 41 0.58 8.86 26.88 5.00
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