P:Substantia nigra

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Pain Term
Category Anatomy
Synonyms None
Pain Specific No
Documents 1369
Hot Single Events 200
Hot Interactions 84

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Substantia nigra. They are ordered first by their pain relevance and then by number of times they were reported for Substantia nigra. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT29380 Binding of gp and Mme 1 0.01 0 0.71 100.00
2 INT17300 Prss12 Positive_regulation of Localization of Acot1 4 0.11 0 3.28 99.92
3 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16 99.64
4 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43 99.60
5 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25 99.56
6 INT346323 Binding of Gopc and Obfc1 1 0.01 0 0.08 99.56
7 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 0.03 0.07 0.49 99.52
8 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2 98.88
9 INT23755 Mptp1 Regulation of PDYN 1 0.01 2.27 1.98 98.86
10 INT132152 Adra2a Regulation of Localization of Abat 1 0.03 0 0.66 98.80
11 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 98.44
12 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 98.44
13 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62 98.12
14 INT161011 Binding of Cpe and St13 2 0.03 0.61 1.07 97.88
15 INT161009 Binding of Cpe and Itgam 1 0.03 0.53 0.37 97.88
16 INT161004 Binding of Cpe and Cpb2 1 0.03 0.53 0.37 97.88
17 INT161000 Binding of Cpe and Gfap 1 0.05 0.53 0.37 97.88
18 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42 97.64
19 INT105716 Vta1 Regulation of Nfasc 1 0.14 0 1.89 97.40
20 INT105717 Vta1 Regulation of Nfasc Regulation of Nfasc 1 0.15 0 0.63 97.40
21 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 97.10
22 INT18649 Binding of Slc3a1 and Ptgdr 1 0.13 0 0.22 96.68
23 INT69206 Ntf3 Negative_regulation of Ntf3 Positive_regulation of Penk 1 0.05 0.06 0.66 96.68
24 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66 96.68
25 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37 96.66
26 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37 96.66
27 INT161001 Itgam Regulation of Gfap 1 0.13 0.52 0.37 96.66
28 INT161002 Binding of Itgam and St13 1 0.11 0.52 0.37 96.66
29 INT161008 Itgam Regulation of St13 1 0.08 0.52 0.37 96.66
30 INT29382 Positive_regulation of gp Regulation of Mme 1 0.02 0 0.65 96.60
31 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5 96.52
32 INT161005 Binding of Gfap and St13 1 0.15 0.52 0.37 96.46
33 INT161010 Gfap Regulation of St13 1 0.05 0.52 0.37 96.46
34 INT161007 Gfap Regulation of Cpb2 1 0.04 0.52 0.37 96.46
35 INT160999 Binding of Gfap and Cpb2 1 0.14 0.52 0.37 96.46
36 INT17299 Prss12 Regulation of Localization of Acot1 3 0.05 0 2.07 96.40
37 INT29381 gp Regulation of Mme 1 0.01 0 0.65 96.16
38 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22 95.76
39 INT338443 Binding of Gad1 and Slc32a1 1 0.31 0.64 0.18 95.44
40 INT159457 Binding of Vamp1 and Inadl2 1 0.00 0.36 0.29 94.92
41 INT328409 Nlrp1a Regulation of Gopc 1 0.04 0.37 0.13 94.84
42 INT50889 Binding of HTR1A and HTR1D 2 0.40 0.31 1.05 94.24
43 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84 94.12
44 INT60718 Negative_regulation of Insrr Positive_regulation of Fos 1 0.01 0.6 0.42 94.12
45 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38 93.92
46 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51 93.12
47 INT24127 Cast Positive_regulation of Mme 1 0.15 0 0.33 92.36
48 INT149929 Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.12 0 0.61 92.32
49 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51 92.28
50 INT134294 Binding of Pdyn and Penk 1 0.23 0 2.69 91.48
51 INT159456 Negative_regulation of Binding of Vamp1 and Ppidl1 1 0.00 0.42 0.28 90.84
52 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05 90.72
53 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55 90.64
54 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31 90.64
55 INT159455 Binding of Vamp1 and Ppidl1 1 0.00 0.84 0.57 90.36
56 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24 89.68
57 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66 89.56
58 INT29906 Binding of Scn4a and Ap2m1 1 0.09 0 0.43 88.44
59 INT216086 Binding of Nrtn and Fig4 1 0.03 0.23 0.04 88.32
60 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6 88.28
61 INT56431 Vta1 Regulation of Regulation of Oprl1 1 0.07 0 0.89 88.08
62 INT189999 Binding of Vta1 and Cfp 2 0.08 1.25 1.97 87.68
63 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95 87.64
64 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78 86.80
65 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57 86.64
66 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57 86.64
67 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64 84.96
68 INT111790 Penk Regulation of Gene_expression of Npr1 1 0.22 0.56 0.86 84.96
69 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46 84.76
70 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04 83.12
71 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12 82.76
72 INT342404 Binding of AAVS1 and Syp 1 0.04 0.07 0.08 82.72
73 INT103536 Obfc1 Regulation of Gene_expression of Penk 1 0.00 0.08 0.46 82.64
74 INT311557 Binding of ROS1 and Ptpn2 1 0.02 2.32 0.46 82.36
75 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69 82.00
76 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19 81.76
77 INT349686 Nmu Positive_regulation of Nmur1 1 0.36 0.2 0.45 81.76
78 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1 81.60
79 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66 81.24
80 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68 81.12
81 INT300972 Mtap2 Regulation of Coq10a 1 0.24 0.37 0.04 80.96
82 INT26235 Binding of GSR and Htr1a 1 0.12 0.09 0.31 80.92
83 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3 80.72
84 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41 80.16
85 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09 79.88
86 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83 78.24
87 INT41152 Binding of Penk and Slc3a1 3 0.12 0.11 2.91 78.12
88 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83 77.96
89 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83 77.52
90 INT131312 Binding of Nts and Datd 1 0.10 0.74 0.46 77.48
91 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29 77.44
92 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29 77.44
93 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08 77.04
94 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42 75.88
95 INT139488 Oprm1 Positive_regulation of Cnr1 1 0.17 0.1 0.42 75.88
96 INT139489 Oprm1 Positive_regulation of Penk 1 0.23 0.1 0.42 75.88
97 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42 75.88
98 INT342403 Regulation of Binding of AAVS1 and Syp 1 0.04 0 0.04 75.76
99 INT342406 AAVS1 Positive_regulation of Icam1 1 0.26 0.19 0.11 75.24
100 INT243494 Binding of Vta1 and LOC308670 1 0.01 0.06 1.06 75.20
101 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21 75.00
102 INT53127 Binding of Ntrk2 and Ntf4 1 0.12 0 0.33 75.00
103 INT342405 AAVS1 Positive_regulation of Syp 1 0.05 0.19 0.11 74.80
104 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18 74.12
105 INT261453 Binding of Akr1d1 and Ptgdr 1 0.00 0.56 0.65 73.92
106 INT338447 GAD1 Negative_regulation of Slc32a1 1 0.04 0.59 0.47 73.92
107 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76 73.76
108 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44 73.76
109 INT270983 Binding of Cpe and GSTK1 1 0.01 0.12 0.07 73.60
110 INT348129 Bgn Regulation of Regulation of Hspg2 1 0.00 0.69 0.69 71.96
111 INT251453 Binding of Kcnc1 and Dpp10 1 0.20 0.18 0.18 71.60
112 INT344114 Slc3a1 Positive_regulation of GYPE 1 0.01 0 0.57 70.88
113 INT344115 Positive_regulation of Slc3a1 Positive_regulation of GYPE 1 0.01 0 0.58 69.76
114 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16 69.60
115 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55 69.28
116 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82 69.00
117 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35 68.48
118 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 0.10 0.74 0.03 68.28
119 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48 67.84
120 INT5585 da Negative_regulation of Gene_expression of Penk 1 0.00 0 0.59 67.64
121 INT270985 Binding of Slc6a3 and GSTK1 1 0.02 0.05 0.03 66.12
122 INT53823 Cck Regulation of Localization of Pdyn 1 0.09 0 0.95 65.68
123 INT53822 Cck Regulation of Pdyn 1 0.02 0 0.95 65.68
124 INT178720 NOVA2 Regulation of Fig4 1 0.01 0 0.23 64.56
125 INT159454 Binding of Inadl2 and Ppidl1 1 0.03 1.08 0.7 64.44
126 INT353978 Lmx1b Regulation of Gene_expression of Pet1 1 0.31 0.21 0.53 64.08
127 INT116251 Vta1 Positive_regulation of Localization of Pdyn 1 0.01 0 0.74 63.96
128 INT65523 Binding of Adarb1 and Oprl1 1 0.02 0 0.28 63.12
129 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16 63.00
130 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08 62.96
131 INT14576 Tac4 Regulation of Penk 1 0.07 0 1.77 62.64
132 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 62.24
133 INT106144 Binding of NPBWR2 and NPW 1 0.14 0.09 0.16 61.76
134 INT270956 Slc6a3 Positive_regulation of Cpe 1 0.29 0 0.03 61.20
135 INT277432 Ptpn2 Positive_regulation of Gdnf 1 0.29 1.41 0.06 61.04
136 INT106145 Binding of NPBWR1 and NPW 1 0.12 0.09 0.16 61.04
137 INT277429 Ptpn2 Regulation of Gdnf 1 0.34 0.47 0.03 61.04
138 INT277427 Ptpn2 Positive_regulation of Gene_expression of Gdnf 1 0.32 0.47 0.03 61.04
139 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15 60.64
140 INT270987 Slc6a3 Positive_regulation of Binding of Slc6a3 and Cpe 1 0.26 0 0.03 58.36
141 INT270941 Slc6a3 Positive_regulation of Binding of Cpe 1 0.29 0 0.03 58.36
142 INT261452 Ptgdr Positive_regulation of Hrasls 1 0.02 0.3 0.33 58.16
143 INT297738 Cbr1 Positive_regulation of Ifih1 1 0.01 1.83 0.39 57.68
144 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 57.56
145 INT261462 Akr1d1 Positive_regulation of Hrasls 1 0.00 0.3 0.33 56.88
146 INT332540 Cxadr Regulation of Gene_expression of AD5 1 0.09 0.25 0.14 56.68
147 INT313448 Gene_expression of Syp Positive_regulation of Th 1 0.28 0 0.03 56.16
148 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89 55.60
149 INT264931 Binding of Gnaz and Hrh1 1 0.01 0.83 1.12 55.60
150 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03 53.84
151 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35 53.68
152 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66 53.68
153 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66 53.28
154 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29 53.12
155 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 53.12
156 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28 53.12
157 INT286703 Mapk1 Positive_regulation of Phosphorylation of Hist1h3f 1 0.22 0.18 0.29 52.72
158 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 52.72
159 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28 52.72
160 INT286709 Mapk1 Positive_regulation of Rps6ka5 Positive_regulation of Rps6ka5 1 0.36 0.18 0.28 52.72
161 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28 52.72
162 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5 52.00
163 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28 51.84
164 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85 51.12
165 INT277428 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.29 0.47 0.03 50.88
166 INT118462 BMP7 Regulation of Bmp7 1 0.19 0 0.06 50.64
167 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98 50.40
168 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63 50.40
169 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08 50.40
170 INT277435 Ptpn2 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.20 0.94 0.05 50.36
171 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16 49.76
172 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61 46.48
173 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92 46.40
174 INT313430 Syp Positive_regulation of Ppp2ca 1 0.66 0.08 0.09 45.76
175 INT346326 Binding of Gpi1 and Gopc 1 0.04 0.28 0.07 43.08
176 INT226062 IgG-2a Negative_regulation of Cntn5 1 0.00 0 0 42.28
177 INT199285 Tg(Foxn1)E1Hon Regulation of Gene_expression of Mapt 1 0.01 0.52 0.36 41.60
178 INT258087 Negative_regulation of ANTXR2 Negative_regulation of Gene_expression of IGFBP3 1 0.04 0.29 0 41.48
179 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5 40.96
180 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3 40.64
181 INT311532 ROS1 Regulation of RYR3 1 0.43 0.18 0.25 40.16
182 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 39.72
183 INT199286 Tg(Foxn1)E1Hon Regulation of Gene_expression of Oprm1 1 0.13 0.32 0.28 39.56
184 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48 38.12
185 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19 38.12
186 INT313461 Gopc Regulation of Th 1 0.07 0 0 37.76
187 INT258574 Cysltr1 Positive_regulation of Positive_regulation of Cnr1 1 0.01 0.07 0.32 37.48
188 INT353981 Gene_expression of Pet1 Positive_regulation of Lmx1b 1 0.53 0 0.23 37.20
189 INT261498 CBS Positive_regulation of DSE 1 0.00 0 0.5 35.20
190 INT311533 ROS1 Positive_regulation of Positive_regulation of RYR3 1 0.28 0.18 0.26 33.04
191 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2 32.60
192 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09 31.36
193 INT299000 Positive_regulation of Il18 Regulation of Ltp 1 0.05 0.35 0.2 29.68
194 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53 28.88
195 INT54491 Positive_regulation of Akr1d1 Positive_regulation of Binding of Jun and Rabep2 1 0.00 0 0.53 28.88
196 INT18125 Binding of OPRM1 and Penk 1 0.54 0 0.4 28.08
197 INT328411 Nlrp1a Negative_regulation of Pdgfb 1 0.08 0.39 0 26.20
198 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1 25.00
199 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24 24.00
200 INT291450 Kcnn3 Negative_regulation of Gene_expression of SK 1 0.10 0.53 0.08 21.36

Single Events

The table below shows the top 200 pain related interactions that have been reported for Substantia nigra. They are ordered first by their pain relevance and then by number of times they were reported in Substantia nigra. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
2 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 100.00
3 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
4 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 100.00
5 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
6 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9 100.00
7 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 100.00
8 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56 100.00
9 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
10 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31 100.00
11 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 100.00
12 INT336 Negative_regulation of Gad1 19 0.58 7.71 9.51 100.00
13 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
14 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33 100.00
15 INT771 Regulation of Nts 93 0.61 13.13 53.57 100.00
16 INT946 Negative_regulation of Nts 60 0.57 4.61 34.44 100.00
17 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2 100.00
18 INT85542 Negative_regulation of Calb2 5 0.38 5.4 3.18 100.00
19 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17 100.00
20 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31 100.00
21 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 100.00
22 INT26614 Positive_regulation of Siglec1 2 0.33 0.36 2 100.00
23 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 100.00
24 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
25 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
26 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64 100.00
27 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 100.00
28 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01 100.00
29 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75 100.00
30 INT120415 Regulation of Nol3 1 0.44 0.73 1.41 100.00
31 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
32 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 100.00
33 INT160993 Negative_regulation of Cpb2 2 0.18 1.68 0.83 100.00
34 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 100.00
35 INT131920 Positive_regulation of Gene_expression of Nlrp1a 4 0.08 2.23 2.02 100.00
36 INT90932 Negative_regulation of Positive_regulation of Penk 3 0.41 0.36 2.66 100.00
37 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 100.00
38 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94 100.00
39 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
40 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95 100.00
41 INT110520 Negative_regulation of Crygb 6 0.31 2.32 4.71 100.00
42 INT245663 Phosphorylation of Syp 2 0.76 7.4 1.88 100.00
43 INT129585 Gene_expression of St13 17 0.59 4.46 9.3 100.00
44 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
45 INT106151 Gene_expression of NPW 1 0.32 0.36 0.4 100.00
46 INT129590 Localization of St13 4 0.61 0.67 1.03 100.00
47 INT102516 Gene_expression of Map2 29 0.69 6.73 3.41 100.00
48 INT243794 Gene_expression of FGF20 1 0.62 0.61 0.44 100.00
49 INT30326 Regulation of LOC100366054 1 0.11 0.09 1.01 100.00
50 INT90825 Gene_expression of NFKBIB 3 0.17 4.13 1.41 100.00
51 INT195527 Binding of Rela 17 0.25 4.42 3.56 100.00
52 INT343975 Negative_regulation of SNAPC1 1 0.00 0.12 0.22 100.00
53 INT154190 Binding of Mtap2 3 0.31 0.31 0.43 100.00
54 INT79491 Binding of Inadl2 5 0.17 1.67 5.37 100.00
55 INT103531 Regulation of Positive_regulation of Gad1 3 0.61 0.31 1.43 100.00
56 INT31890 Positive_regulation of Protein_catabolism of Tac1 1 0.06 0 0.56 100.00
57 INT27687 Regulation of Cp 20 0.53 9.75 10.8 100.00
58 INT39838 Regulation of Gene_expression of Cp 6 0.17 0.64 0.91 100.00
59 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 100.00
60 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 100.00
61 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45 100.00
62 INT143316 Negative_regulation of Slc18a2 7 0.50 3.17 2.52 100.00
63 INT61417 Gene_expression of ITGAL 36 0.75 29.62 6.15 100.00
64 INT139297 Regulation of Porcn 2 0.07 0.51 0.29 100.00
65 INT79983 Negative_regulation of Gene_expression of GAD1 7 0.41 4.02 1.9 100.00
66 INT131923 Negative_regulation of Gene_expression of COX1 1 0.29 0.35 0.5 100.00
67 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 100.00
68 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 100.00
69 INT90824 Positive_regulation of Gene_expression of NFKBIB 1 0.13 1.19 0.54 100.00
70 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
71 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04 100.00
72 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85 100.00
73 INT101537 Gene_expression of Vta1 19 0.50 1.88 20.76 100.00
74 INT117495 Gene_expression of Pars2 13 0.38 7.93 4.24 100.00
75 INT207082 Positive_regulation of Pars2 10 0.14 5.45 2.22 100.00
76 INT246000 Positive_regulation of Gene_expression of Vta1 3 0.30 0.35 1.62 100.00
77 INT17296 Regulation of Positive_regulation of Acot1 2 0.24 0.29 0.65 100.00
78 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.98
79 INT37151 Localization of Th 13 0.57 3.11 4.82 99.98
80 INT29477 Transcription of Oprl1 52 0.72 5.05 30.52 99.96
81 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 99.96
82 INT60826 Negative_regulation of Positive_regulation of Ache 3 0.50 0.68 0.73 99.96
83 INT52156 Regulation of SCG2 6 0.62 0.4 2.01 99.96
84 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11 99.96
85 INT90827 Positive_regulation of ARTN 3 0.08 1.28 0.93 99.96
86 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 99.92
87 INT35707 Gene_expression of Nlrp1a 20 0.75 9.61 9.32 99.92
88 INT36286 Binding of Cd3e 33 0.36 10.11 3.21 99.92
89 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58 99.92
90 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47 99.92
91 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 99.90
92 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 99.90
93 INT56686 Regulation of Vta1 26 0.44 3.43 24.48 99.90
94 INT114393 Positive_regulation of Vta1 15 0.29 0.75 10.64 99.90
95 INT19071 Localization of Ache 66 0.81 5.1 16.27 99.88
96 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 99.88
97 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.88
98 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43 99.88
99 INT131689 Localization of Vta1 8 0.48 0.57 7.64 99.88
100 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 99.86
101 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05 99.86
102 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 99.86
103 INT51237 Localization of Mep1a 1 0.58 0 1.42 99.86
104 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.84
105 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 99.84
106 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87 99.84
107 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.84
108 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19 99.84
109 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 99.84
110 INT125272 Gene_expression of Slc32a1 11 0.65 0.47 2.64 99.84
111 INT13752 Binding of Scn4a 24 0.36 5.68 14.16 99.84
112 INT309361 Negative_regulation of Gene_expression of Slc32a1 2 0.48 0.22 0.39 99.84
113 INT334716 Negative_regulation of NDUFV1 1 0.01 1.59 0.23 99.84
114 INT29904 Negative_regulation of Binding of Scn4a 4 0.41 1.21 1.56 99.84
115 INT29331 Positive_regulation of Srms 3 0.21 1.65 2.69 99.84
116 INT24656 Regulation of Neo1 1 0.19 0 2.18 99.82
117 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46 99.82
118 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85 99.82
119 INT56461 Localization of Vta1 23 0.59 2.03 20.74 99.80
120 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.80
121 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 99.80
122 INT349306 Negative_regulation of Rasd2 1 0.04 1.41 0.27 99.80
123 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.80
124 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4 99.78
125 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 99.76
126 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 99.76
127 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 99.76
128 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 99.76
129 INT20712 Regulation of gp 8 0.36 1.06 1.67 99.76
130 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45 99.76
131 INT30237 Regulation of Dmgdh 1 0.13 0.1 1.44 99.74
132 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67 99.72
133 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.72
134 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 99.70
135 INT21185 Binding of Ptprg 213 0.47 13.49 157.75 99.68
136 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.68
137 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71 99.68
138 INT7491 Localization of Pdyn 80 0.81 3.94 58.77 99.68
139 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.68
140 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 99.68
141 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 99.68
142 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.68
143 INT7327 Regulation of Th 164 0.62 29.67 110.14 99.68
144 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9 99.68
145 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1 99.68
146 INT10118 Positive_regulation of Localization of Pdyn 15 0.70 0.77 19.5 99.68
147 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 99.68
148 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18 99.68
149 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.68
150 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 99.68
151 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 99.68
152 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.68
153 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08 99.68
154 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82 99.68
155 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05 99.68
156 INT2212 Binding of Abat 89 0.48 18.36 63.99 99.68
157 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.68
158 INT247794 Localization of Cxadr 4 0.76 3.17 0.45 99.68
159 INT13041 Binding of Htr1b 14 0.47 4.92 7.95 99.68
160 INT127978 Gene_expression of Trpc5 58 0.67 3.11 10.21 99.68
161 INT695 Binding of POMC 304 0.48 56.66 126.85 99.68
162 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79 99.68
163 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24 99.68
164 INT177316 Localization of CXADR 9 0.77 1.05 0.64 99.68
165 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62 99.68
166 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 99.68
167 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 99.68
168 INT75982 Positive_regulation of Binding of Htr1b 1 0.49 0 0.43 99.68
169 INT114702 Gene_expression of Fgf1 34 0.74 17.39 2.96 99.68
170 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.68
171 INT76142 Positive_regulation of Regulation of Fgf2 2 0.47 0.34 0.64 99.68
172 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.68
173 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 99.68
174 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02 99.68
175 INT9780 Regulation of Penk 30 0.60 6.78 17.19 99.68
176 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49 99.68
177 INT55587 Negative_regulation of Positive_regulation of Gad1 6 0.49 1.1 1.82 99.68
178 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 99.66
179 INT48536 Positive_regulation of Grm8 46 0.61 14.31 23.56 99.66
180 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93 99.66
181 INT90826 Localization of NFASC 8 0.17 6.01 1.97 99.66
182 INT90828 Localization of ARTN 2 0.11 1.43 0.91 99.66
183 INT39733 Localization of NFKB1 59 0.79 22.76 13.99 99.66
184 INT6594 Gene_expression of HTR1D 60 0.75 10.15 27.13 99.64
185 INT24655 Negative_regulation of Neo1 4 0.35 0.32 2.42 99.64
186 INT33538 Gene_expression of Axtav 1 0.00 0.34 3.23 99.62
187 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.60
188 INT31431 Negative_regulation of Anxa10 5 0.37 0 5.24 99.60
189 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 99.60
190 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97 99.60
191 INT133590 Gene_expression of Nrtn 17 0.55 6.1 3.64 99.60
192 INT216082 Positive_regulation of Gene_expression of Nrtn 1 0.27 2.38 0.49 99.60
193 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5 99.58
194 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 99.58
195 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 99.58
196 INT343969 Negative_regulation of Localization of AAVS1 1 0.12 0.33 0.41 99.58
197 INT66532 Positive_regulation of Pnoc 46 0.70 14.99 41.39 99.58
198 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67 99.58
199 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22 99.58
200 INT292 Localization of Penk 876 0.81 88.44 669.14 99.56
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