P:Taxol

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 176
Hot Single Events 107
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Taxol. They are ordered first by their pain relevance and then by number of times they were reported for Taxol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 98.76
2 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33 95.84
3 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42 94.76
4 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42 94.76
5 INT288135 Stip1 Regulation of Ifi35 1 0.00 0.85 0.04 80.08
6 INT262147 Nr1i2 Regulation of Gene_expression of Cyp2j8 1 0.00 0.07 0.07 77.52
7 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12 68.68
8 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12 68.68
9 INT262209 Positive_regulation of Nr1i2 Positive_regulation of Transcription of Ppig 1 0.03 0 0.06 60.08
10 INT288134 Pdgfa Regulation of Ifi35 1 0.01 0.78 0.03 58.16
11 INT288138 VEGFA Regulation of Ifi35 1 0.00 0.78 0.03 57.80
12 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06 56.08
13 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08 47.68
14 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08 46.24
15 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46 41.44
16 INT322130 Trpv1 Positive_regulation of Positive_regulation of Trpv4 1 0.15 0.1 0.05 41.12
17 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75 37.24
18 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2 33.84
19 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 31.36
20 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 30.08
21 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27 21.92
22 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 0.13 0.76 0.04 21.40
23 INT142226 Trpa1 Regulation of Trpv1 2 0.35 0.39 0.44 11.12
24 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
25 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11 5.00
26 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42 5.00
27 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
28 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
29 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
30 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
31 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92 5.00
32 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
33 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
34 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
35 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66 5.00
36 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
37 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
38 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
39 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 5.00
40 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54 5.00
41 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 5.00
42 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 5.00
43 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48 5.00
44 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
45 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
46 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45 5.00
47 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44 5.00
48 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4 5.00
49 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38 5.00
50 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 5.00
51 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36 5.00
52 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36 5.00
53 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34 5.00
54 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33 5.00
55 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 5.00
56 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28 5.00
57 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27 5.00
58 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27 5.00
59 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27 5.00
60 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27 5.00
61 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26 5.00
62 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26 5.00
63 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25 5.00
64 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25 5.00
65 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25 5.00
66 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25 5.00
67 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25 5.00
68 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24 5.00
69 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24 5.00
70 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
71 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
72 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
73 INT339570 Gene_expression of Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.5 0.23 5.00
74 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23 5.00
75 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23 5.00
76 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22 5.00
77 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22 5.00
78 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21 5.00
79 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21 5.00
80 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2 5.00
81 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18 5.00
82 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18 5.00
83 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15 5.00
84 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14 5.00
85 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14 5.00
86 INT178446 Binding of Egfr and ras 1 0.04 0.13 0.13 5.00
87 INT178431 Positive_regulation of Binding of Egfr and ras 1 0.05 0.13 0.13 5.00
88 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13 5.00
89 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13 5.00
90 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12 5.00
91 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12 5.00
92 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12 5.00
93 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11 5.00
94 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11 5.00
95 INT262141 Edcs1 Positive_regulation of Nr1i2 1 0.02 0 0.1 5.00
96 INT339533 VEGFA Positive_regulation of Gene_expression of CYP2C8 1 0.09 0.57 0.09 5.00
97 INT262163 Positive_regulation of Binding of Nr1i2 and Plec 1 0.04 0.31 0.09 5.00
98 INT262142 Edcs1 Regulation of Nr1i2 1 0.01 0 0.09 5.00
99 INT262157 Binding of Nr1i2 and Plec 1 0.03 0.3 0.09 5.00
100 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 5.00
101 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08 5.00
102 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08 5.00
103 INT339534 VEGFA Positive_regulation of CYP2C18 1 0.04 0.57 0.08 5.00
104 INT262176 Nr1i2 Regulation of Regulation of Casr 1 0.11 0.17 0.07 5.00
105 INT262219 Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07 5.00
106 INT250662 FNTA Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.79 0.07 5.00
107 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07 5.00
108 INT262168 Nr1i2 Regulation of Casr 1 0.07 0.17 0.07 5.00
109 INT262143 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07 5.00
110 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06 5.00
111 INT262190 Foxo1 Positive_regulation of Pck1 1 0.04 0.15 0.06 5.00
112 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06 5.00
113 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06 5.00
114 INT262145 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.45 0.06 5.00
115 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06 5.00
116 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06 5.00
117 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05 5.00
118 INT178430 Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05 5.00
119 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05 5.00
120 INT178447 Negative_regulation of Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05 5.00
121 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04 5.00
122 INT339569 VEGFA Positive_regulation of Litaf 1 0.18 0.6 0.04 5.00
123 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04 5.00
124 INT262221 Nr1i2 Negative_regulation of Cyp24a1 1 0.27 0.15 0.04 5.00
125 INT219875 Binding of KRT7 and Krt20 1 0.01 1.32 0.04 5.00
126 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 0.03 0.49 0.04 5.00
127 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04 5.00
128 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
129 INT178436 Mapk14 Positive_regulation of Gene_expression of Hist1h1a 1 0.17 0.2 0.04 5.00
130 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04 5.00
131 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04 5.00
132 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04 5.00
133 INT219857 Binding of Krt20 and Nbr1 1 0.00 1.31 0.04 5.00
134 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04 5.00
135 INT262162 Nr1i2 Regulation of Cyp2b9 1 0.14 0.14 0.03 5.00
136 INT262195 Nr1i2 Positive_regulation of Srebf1 1 0.08 0.18 0.03 5.00
137 INT262198 Foxo1 Positive_regulation of Igfbp1 1 0.11 0.08 0.03 5.00
138 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03 5.00
139 INT262171 Binding of Cyp3a11 and Rare1 1 0.02 0.15 0.03 5.00
140 INT262217 Casr Regulation of Cyp3a11 1 0.05 0.13 0.03 5.00
141 INT262149 Binding of Nfe2l2 and Rare1 1 0.03 0.32 0.03 5.00
142 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03 5.00
143 INT262150 Binding of Rare1 and Sfn 1 0.01 0.33 0.03 5.00
144 INT178442 Mapk1 Regulation of Gene_expression of Il6 1 0.03 0.59 0.03 5.00
145 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03 5.00
146 INT262184 Binding of Nr1i2 and Rare1 1 0.03 0.15 0.03 5.00
147 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0 5.00
148 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0 5.00
149 INT262203 Nr1i2 Positive_regulation of Gene_expression of Hmgcs2 1 0.23 0.22 0 5.00
150 INT293615 Nmnat2 Positive_regulation of Nmnat1 1 0.19 0.79 0 5.00
151 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0 5.00
152 INT250656 ELK1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
153 INT322126 Binding of Trpv4 and Fig4 1 0.02 0 0 5.00
154 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0 5.00
155 INT178440 Map2k4 Positive_regulation of Mapk14 1 0.04 0.13 0 5.00
156 INT262170 Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.4 0 5.00
157 INT178448 Mapk1 Regulation of Localization of VEGFA 1 0.01 0.51 0 5.00
158 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0 5.00
159 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
160 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0 5.00
161 INT262204 Nr1i2 Positive_regulation of Cyp3a11 1 0.33 0.08 0 5.00
162 INT262225 Binding of CYP3A4 and Nr1i2 1 0.13 0 0 5.00
163 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0 5.00
164 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0 5.00
165 INT250667 KLF1 Regulation of ERBB2 1 0.00 1.16 0 5.00
166 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
167 INT293613 Wld Positive_regulation of Nmnat1 1 0.42 0.79 0 5.00
168 INT262213 Plec Positive_regulation of Cyp3a11 1 0.02 0 0 5.00
169 INT178433 Fgf1 Positive_regulation of Mapk14 1 0.02 0.65 0 5.00
170 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0 5.00
171 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0 5.00
172 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0 5.00
173 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0 5.00
174 INT178445 Map2k4 Positive_regulation of Mapk8 1 0.11 0.13 0 5.00
175 INT250657 STAT3 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
176 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0 5.00
177 INT262215 Binding of Nr1i2 and Dnajc7 1 0.08 0.26 0 5.00
178 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0 5.00
179 INT293617 Wld Positive_regulation of Nmnat2 1 0.65 1.9 0 5.00
180 INT262191 Binding of Nr1i2 and Foxo1 1 0.22 0.09 0 5.00
181 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0 5.00
182 INT178432 Map2k7 Positive_regulation of Mapk8 1 0.11 0.13 0 5.00
183 INT187640 Binding of EGFR and KLF1 3 0.01 2.54 0 5.00
184 INT261844 Lyn Positive_regulation of Lyn Regulation of Trpv4 1 0.01 0.19 0 5.00
185 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0 5.00
186 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0 5.00
187 INT178429 Negative_regulation of Mapk1 Negative_regulation of Positive_regulation of Eno2 1 0.02 0.73 0 5.00
188 INT262156 Nr1i2 Negative_regulation of Gene_expression of Hmgcs2 1 0.22 0.22 0 5.00
189 INT262174 Binding of Casr and Foxo1 1 0.05 0.09 0 5.00
190 INT262192 Nr1i2 Regulation of Positive_regulation of Cyp3a11 1 0.32 0 0 5.00
191 INT262199 Binding of Cyp2b9 and Rare1 1 0.01 0.15 0 5.00
192 INT250669 Binding of TP53 and ST8SIA4 1 0.02 0.51 0 5.00
193 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Taxol. They are ordered first by their pain relevance and then by number of times they were reported in Taxol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17143 Regulation of Cyp2c22 18 0.60 3.02 6.7 100.00
2 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16 100.00
3 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 99.98
4 INT53393 Positive_regulation of Cyp3a62 25 0.70 7.56 17.69 99.98
5 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2 99.98
6 INT158547 Negative_regulation of Positive_regulation of Trpv4 2 0.57 0.47 0.77 99.98
7 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35 99.84
8 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 99.82
9 INT223898 Regulation of Ifi35 11 0.59 15.02 0.6 99.80
10 INT288108 Regulation of Regulation of Ifi35 1 0.02 0.97 0.53 99.80
11 INT149152 Negative_regulation of Trpv4 5 0.58 1.8 1.52 99.80
12 INT110852 Binding of Pkia 1 0.12 1.04 0.3 99.76
13 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 99.76
14 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.74
15 INT156175 Positive_regulation of Positive_regulation of Trpv4 5 0.50 0.86 0.8 99.58
16 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.44
17 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39 99.40
18 INT61237 Positive_regulation of Cyp3a2 4 0.63 1.01 0.96 99.32
19 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 99.32
20 INT4340 Positive_regulation of Localization of Ldha 46 0.70 14.52 15.66 99.24
21 INT116775 Negative_regulation of Itgb1 2 0.07 1.43 1.27 99.22
22 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 99.18
23 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88 99.10
24 INT29695 Regulation of Positive_regulation of Cyp2c22 2 0.15 0.56 1.14 99.10
25 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 99.06
26 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 98.98
27 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12 98.84
28 INT3920 Localization of Ldha 241 0.81 83.08 58.72 98.84
29 INT169402 Binding of Trpv4 8 0.47 5.13 2.78 98.60
30 INT67549 Positive_regulation of Positive_regulation of Cyp3a62 1 0.50 0.61 1.14 98.52
31 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94 98.32
32 INT250672 Negative_regulation of jd 1 0.01 1.09 0.05 98.28
33 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 98.24
34 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 98.16
35 INT31759 Negative_regulation of Gene_expression of Egf 6 0.53 5.33 0.77 97.80
36 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84 97.52
37 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31 97.52
38 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13 97.44
39 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91 97.44
40 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 97.24
41 INT293584 Positive_regulation of Wld 1 0.66 2.71 0.31 97.24
42 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97 97.16
43 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 97.12
44 INT46797 Negative_regulation of Cyp3a62 27 0.59 7.06 13.97 97.12
45 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04 97.12
46 INT250670 Negative_regulation of Phosphorylation of Birc5 2 0.57 1.17 0.09 97.00
47 INT110854 Phosphorylation of Egf 8 0.75 5.62 0.67 96.68
48 INT193106 Phosphorylation of Birc5 3 0.80 2.13 0.09 96.44
49 INT115199 Localization of Trpv4 12 0.79 3.65 2.5 95.76
50 INT261816 Positive_regulation of Localization of Trpv4 2 0.47 1.16 1.07 95.76
51 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64 95.08
52 INT49460 Positive_regulation of TPPP3 1 0.67 0 0.59 94.80
53 INT49461 Positive_regulation of Positive_regulation of TPPP3 1 0.45 0 0.59 94.80
54 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 94.56
55 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74 94.32
56 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 94.08
57 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9 94.08
58 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 93.72
59 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 93.44
60 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 93.36
61 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 93.08
62 INT691 Binding of SST 67 0.48 24.66 32.67 92.32
63 INT199652 Negative_regulation of Fxn 3 0.54 12.37 0.11 92.32
64 INT4929 Binding of Mbp 25 0.48 18.01 9.41 92.08
65 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 92.08
66 INT223901 Negative_regulation of Ifi35 3 0.49 8.03 0.81 92.04
67 INT187017 Positive_regulation of Bcar1 2 0.44 2.02 0.27 91.36
68 INT60585 Regulation of TP53 59 0.59 54.55 5.21 90.24
69 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 90.16
70 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 89.60
71 INT127406 Negative_regulation of ENOX2 2 0.57 1.5 0.89 89.20
72 INT106017 Positive_regulation of Dbt 3 0.40 1.67 0.39 88.76
73 INT223897 Localization of Ifi35 3 0.72 3.9 0.22 88.72
74 INT293581 Positive_regulation of Nmnat2 1 0.59 4.33 0.86 88.00
75 INT242561 Positive_regulation of Kpnb1 2 0.05 1.96 0.29 88.00
76 INT124090 Gene_expression of Gadd45a 9 0.63 3.25 0.99 87.36
77 INT124093 Negative_regulation of Gene_expression of Gadd45a 2 0.35 1.52 0.71 87.36
78 INT291510 Gene_expression of Pmaip1 1 0.29 0.5 0.04 87.36
79 INT291517 Gene_expression of Sesn1 1 0.31 0.5 0.04 87.36
80 INT288109 Localization of Kdr 4 0.46 2.84 0.33 87.08
81 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 86.72
82 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 86.72
83 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68 86.68
84 INT110550 Regulation of CYP2C8 3 0.45 1.59 1.34 86.60
85 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 86.40
86 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 86.16
87 INT58919 Localization of Gap43 10 0.78 3.53 4.61 86.16
88 INT122014 Positive_regulation of Trpc3 3 0.67 0.36 0.79 85.88
89 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 85.64
90 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 85.56
91 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77 85.36
92 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89 85.36
93 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 85.28
94 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 84.32
95 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 84.16
96 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 83.16
97 INT100195 Negative_regulation of SPANXB1 5 0.48 2.7 0.82 83.16
98 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 82.96
99 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 82.96
100 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 82.08
101 INT108173 Gene_expression of Abcb1b 14 0.75 8.61 4.26 81.84
102 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 81.36
103 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 80.76
104 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04 80.76
105 INT62272 Negative_regulation of CDK1 9 0.57 6.46 0.46 80.76
106 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 80.20
107 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45 80.16
108 INT293582 Negative_regulation of Positive_regulation of Nmnat2 1 0.36 0.78 0.26 80.00
109 INT149153 Positive_regulation of Gene_expression of Trpv4 12 0.70 3.37 1.72 77.84
110 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 77.76
111 INT262131 Gene_expression of Cyp2j8 1 0.01 0.07 0.07 77.52
112 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02 77.36
113 INT288107 Localization of Taf1 1 0.10 0.49 0.09 77.32
114 INT250676 Gene_expression of jd 1 0.01 1.01 0.04 77.28
115 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 77.04
116 INT57923 Gene_expression of CYP3A 12 0.71 2.62 2 77.04
117 INT148937 Positive_regulation of Csk 2 0.13 2.25 1.63 76.64
118 INT262129 Gene_expression of Cyp2b6l 1 0.01 0.07 0.07 76.64
119 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 76.48
120 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 76.36
121 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65 76.32
122 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11 76.32
123 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 76.00
124 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 75.92
125 INT283191 Negative_regulation of Gene_expression of FDFT1 1 0.02 0.34 0.07 74.68
126 INT200942 Gene_expression of FDFT1 3 0.35 0.5 0.15 74.68
127 INT116776 Gene_expression of Itgb1 2 0.12 1.93 1.66 74.64
128 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 74.16
129 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39 73.92
130 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 72.08
131 INT92139 Binding of MLH1 12 0.42 15.62 1 72.08
132 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 71.68
133 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 71.36
134 INT283190 Negative_regulation of ATP2A1 1 0.42 0.43 0.07 71.36
135 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 71.36
136 INT128498 Regulation of CCND1 17 0.39 12.51 0.58 71.36
137 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45 71.36
138 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 70.52
139 INT158644 Negative_regulation of CDC25A 2 0.23 2.63 1.55 70.24
140 INT158645 Regulation of CDC25A 2 0.39 1.34 0.36 70.24
141 INT96200 Gene_expression of PGP 9 0.76 0.79 1.63 69.92
142 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 69.68
143 INT262138 Positive_regulation of Regulation of CYP3A4 1 0.15 0.06 0.07 69.68
144 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 69.48
145 INT158642 Regulation of Positive_regulation of CHEK2 1 0.07 1.27 0.25 69.44
146 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 69.28
147 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 69.28
148 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 69.28
149 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98 68.92
150 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89 68.68
151 INT346446 Negative_regulation of Regulation of Atf3 1 0.38 0.58 0.39 68.36
152 INT149349 Regulation of Atf3 8 0.45 10 3.85 67.96
153 INT158641 Positive_regulation of CHEK2 5 0.35 4.15 0.37 67.76
154 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 66.76
155 INT4822 Localization of Ca2 417 0.80 99.57 96.45 66.64
156 INT171820 Localization of Fig4 144 0.65 27.38 20.88 66.64
157 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31 66.48
158 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68 66.48
159 INT211527 Negative_regulation of Stip1 2 0.01 0.91 0.09 66.20
160 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 65.84
161 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15 65.84
162 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 65.28
163 INT178400 Negative_regulation of Gene_expression of Dusp1 4 0.40 3.61 0.31 65.28
164 INT96199 Negative_regulation of PGP 15 0.59 1.07 2.35 65.12
165 INT254367 Transcription of TEK 1 0.14 1.08 0.36 64.32
166 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 63.68
167 INT288116 Gene_expression of Stip1 1 0.01 0.79 0.09 63.64
168 INT323284 Negative_regulation of EPHX2 4 0.14 8.25 0.54 63.28
169 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66 63.04
170 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 62.36
171 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63 61.84
172 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31 61.24
173 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91 60.72
174 INT262035 Positive_regulation of Transcription of Ppig 1 0.03 0.05 0.06 60.72
175 INT199785 Transcription of Ppig 2 0.15 0.6 0.06 60.08
176 INT250708 Negative_regulation of PIK3CB 17 0.30 3.09 0.94 59.28
177 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 58.92
178 INT9908 Negative_regulation of IAPP 29 0.57 19.37 2.12 58.92
179 INT158327 Negative_regulation of Mcl1 5 0.42 4.08 0.55 58.92
180 INT293588 Gene_expression of Nmnat2 1 0.76 8.52 0.21 58.48
181 INT293606 Negative_regulation of Gene_expression of Nmnat2 1 0.42 0.54 0.09 58.48
182 INT69968 Negative_regulation of BCO2 2 0.04 0.95 0.63 57.68
183 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 57.28
184 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 57.08
185 INT250714 Positive_regulation of STK25 2 0.26 2.14 0.13 57.08
186 INT219963 Positive_regulation of SPAG9 2 0.15 2.38 0.03 57.08
187 INT35380 Binding of Fn1 8 0.35 4.84 2.23 56.08
188 INT114718 Positive_regulation of Gene_expression of CYP3A4 17 0.49 4.69 4.69 55.56
189 INT322158 Phosphorylation of Csk 2 0.10 1.49 0.52 55.44
190 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55 54.72
191 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7 54.72
192 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71 54.72
193 INT7464 Regulation of Mbp 25 0.62 6.62 6.43 54.40
194 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 54.16
195 INT173159 Localization of PPARA 96 0.74 64.55 10.26 54.16
196 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68 54.16
197 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74 54.16
198 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 53.64
199 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 53.64
200 INT159809 Localization of Trpv4 6 0.78 3.67 2.46 52.76
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