P:Thermal hyperalgesia

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Pain Term
Category Pain type
Synonyms None
Pain Specific Yes
Documents 1334
Hot Single Events 200
Hot Interactions 161

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thermal hyperalgesia. They are ordered first by their pain relevance and then by number of times they were reported for Thermal hyperalgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4 100.00
2 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61 100.00
3 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93 100.00
4 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93 100.00
5 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 100.00
6 INT276865 Regulation of Trpv1 Regulation of Gene_expression of Gpr65 1 0.25 0.62 0.76 100.00
7 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68 99.82
8 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66 99.82
9 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37 99.68
10 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69 99.68
11 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 99.64
12 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13 99.26
13 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13 99.26
14 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13 99.26
15 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13 99.26
16 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13 99.26
17 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12 99.26
18 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12 99.26
19 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12 99.26
20 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12 99.26
21 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61 99.20
22 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61 99.20
23 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54 99.16
24 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93 99.14
25 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79 99.04
26 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12 99.02
27 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12 99.02
28 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12 99.02
29 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28 99.00
30 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46 98.96
31 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67 98.88
32 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16 98.88
33 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61 98.88
34 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01 98.84
35 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1 98.84
36 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1 98.84
37 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 98.84
38 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12 98.80
39 INT148448 Inhbe Positive_regulation of Trpv1 1 0.08 0.7 0.67 98.60
40 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1 98.48
41 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06 98.48
42 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75 98.48
43 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9 98.44
44 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9 98.32
45 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11 98.04
46 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42 98.04
47 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 97.60
48 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 97.56
49 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34 97.20
50 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25 97.20
51 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 96.88
52 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 96.76
53 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11 96.72
54 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06 96.72
55 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06 96.72
56 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05 96.72
57 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05 96.72
58 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05 96.72
59 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05 96.72
60 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 96.64
61 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58 96.64
62 INT335433 Cysltr2 Regulation of Trpv1 1 0.28 0.45 0.55 96.44
63 INT113743 Mc3r Regulation of Gene_expression of Agrp 1 0.05 0.9 0.98 96.36
64 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13 96.28
65 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39 96.08
66 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72 95.92
67 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59 95.80
68 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98 95.80
69 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 95.64
70 INT164287 Ltb4r Positive_regulation of Cysltr2 2 0.41 1.88 1.02 95.60
71 INT335438 Ltb4r2 Positive_regulation of Cysltr2 1 0.04 0.77 0.42 95.60
72 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98 95.44
73 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 95.36
74 INT287754 Lpar2 Positive_regulation of Gene_expression of Lpar1 1 0.44 0.48 0.39 95.20
75 INT287743 Lpar2 Positive_regulation of Positive_regulation of Lpar1 1 0.44 0.48 0.39 95.20
76 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38 95.00
77 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38 95.00
78 INT142226 Trpa1 Regulation of Trpv1 2 0.35 0.39 0.44 95.00
79 INT164281 Ltb4r Positive_regulation of Cysltr1 2 0.32 1.87 1.02 94.72
80 INT335437 Ltb4r2 Positive_regulation of Cysltr1 1 0.03 0.77 0.41 94.72
81 INT287751 Rbm39 Positive_regulation of Positive_regulation of Lpar1 1 0.01 0.48 0.39 94.64
82 INT287745 Rbm39 Positive_regulation of Gene_expression of Lpar1 1 0.01 0.48 0.39 94.64
83 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22 94.56
84 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4 94.28
85 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01 94.08
86 INT148449 Gene_expression of Inhbe Positive_regulation of Prkaca 1 0.05 0.68 0.71 94.08
87 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41 93.60
88 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4 93.24
89 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64 93.16
90 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35 93.08
91 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35 93.08
92 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35 93.08
93 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87 93.04
94 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83 92.88
95 INT251166 Clu Positive_regulation of Trpc3 1 0.09 0.75 0.67 92.84
96 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12 92.68
97 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54 92.64
98 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67 92.56
99 INT151460 Olr1745 Positive_regulation of Il4 1 0.04 0.83 0.59 92.52
100 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57 92.52
101 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57 92.52
102 INT335439 Ltb4r Positive_regulation of Ltb4r2 1 0.09 0.76 0.41 92.48
103 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98 91.36
104 INT118157 Binding of Prkca and Prkcz Positive_regulation of Binding of Prkca Prkcz 1 0.02 0.58 1.55 91.36
105 INT118159 Binding of Prkca and Prkcz Positive_regulation of Prkcz 1 0.02 0.58 1.54 91.36
106 INT118160 Binding of Prkca and Prkcz Positive_regulation of Prkca 1 0.11 0.58 1.54 91.36
107 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81 90.80
108 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01 90.80
109 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74 90.56
110 INT122966 FSCN1 Positive_regulation of FSCN1 Positive_regulation of Bdnf 1 0.02 1.14 1.79 90.36
111 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79 90.36
112 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26 90.32
113 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58 90.32
114 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9 90.20
115 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12 90.12
116 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 90.12
117 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96 90.08
118 INT209250 TRPV1 Positive_regulation of Localization of DRGX 1 0.06 0.82 0.68 90.08
119 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61 89.84
120 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49 89.76
121 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04 89.76
122 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 0.04 1.35 1.4 89.36
123 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32 88.92
124 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13 88.40
125 INT159774 Binding of GRM5 and TRPV1 1 0.40 0.5 0.51 88.40
126 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61 87.92
127 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61 87.92
128 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92 87.52
129 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33 86.96
130 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76 86.84
131 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76 86.84
132 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76 86.84
133 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39 86.72
134 INT114647 Fos Positive_regulation of Gene_expression of PDYN 1 0.48 0.52 0.52 86.64
135 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62 86.40
136 INT122773 Ngf Negative_regulation of Gene_expression of Trpv1 1 0.45 0.8 0.62 86.40
137 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73 85.72
138 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69 85.28
139 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72 84.88
140 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2 84.64
141 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75 84.56
142 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97 84.56
143 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66 84.40
144 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4 84.12
145 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.68 0.71 84.12
146 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46 83.92
147 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 82.60
148 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96 82.52
149 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 82.40
150 INT335436 Ltc4s Regulation of Gene_expression of Cysltr2 1 0.18 0.38 0.58 82.40
151 INT122778 Ngf Negative_regulation of Positive_regulation of Trpv1 1 0.40 0.78 0.61 82.28
152 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61 82.28
153 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8 81.76
154 INT335432 Ltc4s Regulation of Cysltr2 1 0.11 0.38 0.58 81.76
155 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76 81.40
156 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32 80.68
157 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65 80.48
158 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65 80.48
159 INT166303 Adrbk1 Positive_regulation of Binding of Mapk14 and Gpbar1 1 0.22 0.65 0.65 80.48
160 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74 80.24
161 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74 80.24
162 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38 79.88
163 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95 79.84
164 INT126384 Binding of Bdnf and Ntrk2 Positive_regulation of Prkca 1 0.49 0.63 0.85 79.72
165 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61 79.24
166 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75 79.16
167 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26 78.96
168 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68 78.72
169 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 78.48
170 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91 78.44
171 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37 77.80
172 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79 77.44
173 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16 77.20
174 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 77.04
175 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35 76.16
176 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69 75.92
177 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03 75.88
178 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07 75.84
179 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58 75.60
180 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 75.48
181 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91 75.48
182 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07 75.44
183 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8 75.28
184 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79 75.28
185 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 0.04 0.49 1.53 75.24
186 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04 75.20
187 INT96811 Nfkb1 Regulation of Gene_expression of IK 1 0.00 1.06 0.87 75.00
188 INT148541 ST3GAL4 Positive_regulation of Positive_regulation of Trpv1 1 0.08 0.96 0.56 75.00
189 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55 75.00
190 INT148542 ST3GAL4 Regulation of Gene_expression of Trpv1 1 0.05 0.97 0.51 75.00
191 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64 74.88
192 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84 74.76
193 INT114126 Binding of APLNR and OPRL1 1 0.01 0.47 2.85 74.20
194 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 74.08
195 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84 71.84
196 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84 71.56
197 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76 70.28
198 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99 70.12
199 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08 69.96
200 INT224463 TPSAB1 Positive_regulation of F2RL1 2 0.03 1.49 0.76 69.20

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thermal hyperalgesia. They are ordered first by their pain relevance and then by number of times they were reported in Thermal hyperalgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
2 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 100.00
3 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
4 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 100.00
5 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
6 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72 100.00
7 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 100.00
8 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 100.00
9 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
10 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81 100.00
11 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
12 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
13 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63 100.00
14 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 100.00
15 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 100.00
16 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06 100.00
17 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 100.00
18 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26 100.00
19 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 100.00
20 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
21 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
22 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95 100.00
23 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75 100.00
24 INT9347 Localization of Il1b 58 0.81 26.13 31.53 100.00
25 INT73155 Positive_regulation of Positive_regulation of Ngf 11 0.70 5.11 6.7 100.00
26 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 100.00
27 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55 100.00
28 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52 100.00
29 INT115238 Positive_regulation of Gene_expression of Casp1 5 0.68 1.78 0.88 100.00
30 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57 100.00
31 INT335363 Negative_regulation of Negative_regulation of Nmur2 1 0.18 2.31 1.44 100.00
32 INT113736 Negative_regulation of Positive_regulation of Mc4r 1 0.08 1.11 0.93 100.00
33 INT6913 Negative_regulation of Amelx 6 0.32 2.32 5.95 100.00
34 INT2828 Positive_regulation of Ptger3 26 0.68 8.01 9.63 100.00
35 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 100.00
36 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68 100.00
37 INT148237 Positive_regulation of Tbpl1 4 0.49 2.05 1.59 99.98
38 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 99.96
39 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.96
40 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08 99.96
41 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 99.96
42 INT95800 Positive_regulation of Positive_regulation of Ptger1 2 0.43 1.23 1.15 99.96
43 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49 99.96
44 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 99.96
45 INT49884 Negative_regulation of Gene_expression of Il4 18 0.55 14.06 8.9 99.96
46 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96 99.96
47 INT82070 Positive_regulation of Gene_expression of Ntf4 1 0.19 0.26 0.67 99.96
48 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.96
49 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.92
50 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.92
51 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 99.92
52 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71 99.92
53 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.92
54 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 99.92
55 INT71441 Positive_regulation of Pars2 12 0.69 5.75 4.13 99.92
56 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 99.92
57 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86 99.92
58 INT85017 Positive_regulation of Mc4r 13 0.67 7.56 10.86 99.92
59 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.92
60 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 99.92
61 INT25193 Negative_regulation of Pck1 20 0.57 5.66 6.05 99.92
62 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13 99.92
63 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.90
64 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.90
65 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 99.90
66 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.90
67 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28 99.90
68 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 99.90
69 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.90
70 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 99.90
71 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85 99.90
72 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 99.90
73 INT112969 Negative_regulation of Mcpt1 30 0.45 20.17 10.11 99.90
74 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 99.90
75 INT135410 Negative_regulation of Transcription of Mcpt1 2 0.19 1.45 1.22 99.90
76 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 99.88
77 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 99.88
78 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 99.86
79 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 99.86
80 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13 99.86
81 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 99.84
82 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.84
83 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 99.84
84 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21 99.84
85 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 99.84
86 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64 99.84
87 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14 99.84
88 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8 99.84
89 INT41099 Localization of Mdk 5 0.64 2.38 2.89 99.84
90 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.84
91 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22 99.84
92 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.82
93 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.82
94 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.82
95 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 99.82
96 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 99.82
97 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9 99.82
98 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4 99.82
99 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 99.82
100 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 99.82
101 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6 99.82
102 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8 99.82
103 INT157529 Positive_regulation of GRM5 3 0.48 0.59 2.07 99.82
104 INT43922 Gene_expression of Epgn 3 0.58 1.45 0.69 99.82
105 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13 99.82
106 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17 99.80
107 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.80
108 INT10706 Regulation of Il6 150 0.62 93.23 62.34 99.80
109 INT77902 Negative_regulation of Positive_regulation of TRPV1 30 0.59 9.36 19.2 99.80
110 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45 99.80
111 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.76
112 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36 99.76
113 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 99.76
114 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 99.76
115 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98 99.76
116 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25 99.76
117 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 99.76
118 INT269144 Gene_expression of Mia1 8 0.59 11.84 6.16 99.76
119 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 99.74
120 INT169113 Negative_regulation of Phosphorylation of Fos 1 0.42 2.17 3.12 99.74
121 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.72
122 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 99.72
123 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.72
124 INT120148 Positive_regulation of Ea1 2 0.18 2.24 4.7 99.72
125 INT133590 Gene_expression of Nrtn 17 0.55 6.1 3.64 99.72
126 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.70
127 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 99.70
128 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73 99.70
129 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78 99.70
130 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.66
131 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 99.66
132 INT212983 Positive_regulation of Positive_regulation of Nos3 9 0.51 7.08 1.23 99.66
133 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97 99.66
134 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.64
135 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.64
136 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63 99.64
137 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 99.64
138 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1 99.64
139 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13 99.64
140 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.64
141 INT110768 Transcription of Mcpt1 12 0.52 7.66 4.71 99.64
142 INT135409 Transcription of Ccl2 13 0.62 10.59 3.06 99.64
143 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58 99.64
144 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46 99.64
145 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84 99.64
146 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 99.62
147 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 99.62
148 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 99.60
149 INT108268 Negative_regulation of Ap3d1 1 0.02 0.76 0.92 99.60
150 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 99.58
151 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.58
152 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 99.58
153 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 99.58
154 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 99.58
155 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 99.58
156 INT332792 Positive_regulation of Gene_expression of HDAC9 5 0.45 4.61 1.44 99.58
157 INT103037 Transcription of Bdkrb1 8 0.70 4.76 4.33 99.58
158 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 99.56
159 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 99.54
160 INT103169 Negative_regulation of Slc12a5 38 0.58 27.75 20.81 99.54
161 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81 99.54
162 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 99.52
163 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36 99.52
164 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 99.52
165 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 99.52
166 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88 99.52
167 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81 99.52
168 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72 99.50
169 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.50
170 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 99.50
171 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38 99.48
172 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.46
173 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.46
174 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61 99.46
175 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 99.44
176 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 99.44
177 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 99.44
178 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.44
179 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8 99.44
180 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15 99.44
181 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 99.44
182 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 99.44
183 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.44
184 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 99.44
185 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 99.44
186 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31 99.44
187 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9 99.44
188 INT89048 Gene_expression of P2RX2 28 0.75 8.75 7.9 99.44
189 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 99.42
190 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 99.42
191 INT61312 Positive_regulation of Spdya 3 0.10 0.74 5.12 99.42
192 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 99.42
193 INT199387 Binding of Prok2 3 0.37 2.16 1.55 99.42
194 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 99.40
195 INT116428 Gene_expression of Cybb 68 0.76 35.81 7.07 99.40
196 INT153913 Positive_regulation of Lpar1 31 0.70 33.5 16.14 99.40
197 INT71350 Positive_regulation of Tpnr1 3 0.01 3.92 4.08 99.40
198 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93 99.38
199 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.36
200 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32 99.36
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