P:Versed

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pChart

Pain Term
Category Drug
Synonyms Dormicum, Hypnovel, Midazolam
Pain Specific No
Documents 3838
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Versed. They are ordered first by their pain relevance and then by number of times they were reported for Versed. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92 100.00
2 INT83749 Gnrhr Positive_regulation of Gene_expression of Fos 2 0.21 0.14 0.39 99.68
3 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14 99.60
4 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14 99.60
5 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13 91.20
6 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4 90.04
7 INT131357 Agtr2 Regulation of Ren 1 0.04 0.88 0.27 89.84
8 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2 85.76
9 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13 85.76
10 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51 81.76
11 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 78.44
12 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12 74.48
13 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94 67.32
14 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22 63.92
15 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22 63.28
16 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4 55.20
17 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4 55.20
18 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 53.76
19 INT199787 gr Regulation of gr Regulation of CYP2C9 1 0.03 0.63 0 35.20
20 INT199801 gr Regulation of CYP2C9 1 0.08 0.63 0 35.20
21 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02 34.72
22 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01 34.40
23 INT262149 Binding of Nfe2l2 and Rare1 1 0.03 0.32 0.03 25.28
24 INT262150 Binding of Rare1 and Sfn 1 0.01 0.33 0.03 25.28
25 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 25.00
26 INT109502 GBE1 Negative_regulation of HIVEP1 1 0.00 1.85 0 25.00
27 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 19.52
28 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
29 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
30 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08 5.00
31 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5 5.00
32 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
33 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88 5.00
34 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86 5.00
35 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
36 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
37 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
38 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49 5.00
39 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49 5.00
40 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44 5.00
41 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42 5.00
42 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 5.00
43 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26 5.00
44 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26 5.00
45 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
46 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17 5.00
47 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16 5.00
48 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
49 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
50 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04 5.00
51 INT318490 IRF6 Positive_regulation of LTB4R 1 0.01 4.39 1.03 5.00
52 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02 5.00
53 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99 5.00
54 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94 5.00
55 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94 5.00
56 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94 5.00
57 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92 5.00
58 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 5.00
59 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84 5.00
60 INT299987 SPANXB1 Positive_regulation of TRPV1 1 0.20 0.71 0.82 5.00
61 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81 5.00
62 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79 5.00
63 INT224403 Binding of CCK and GYPC 1 0.04 0.83 0.77 5.00
64 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67 5.00
65 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67 5.00
66 INT318476 IRF6 Positive_regulation of Localization of RETNLB 1 0.00 1.42 0.65 5.00
67 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 5.00
68 INT274167 Il13 Regulation of Il5 2 0.09 2.05 0.59 5.00
69 INT318481 IRF6 Positive_regulation of Gene_expression of FPR2 1 0.14 5.09 0.59 5.00
70 INT318487 Negative_regulation of IRF6 Positive_regulation of FPR2 1 0.09 1.39 0.59 5.00
71 INT318488 LTB4R Regulation of FPR2 1 0.01 1.07 0.58 5.00
72 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57 5.00
73 INT313223 Binding of Cx3cr1 and Mcpt1 1 0.06 0.99 0.56 5.00
74 INT313224 Negative_regulation of Binding of Cx3cr1 and Mcpt1 1 0.07 0.99 0.56 5.00
75 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56 5.00
76 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55 5.00
77 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55 5.00
78 INT221783 Nlrp1a Negative_regulation of Camk4 1 0.08 1.39 0.55 5.00
79 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 5.00
80 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53 5.00
81 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53 5.00
82 INT318478 Negative_regulation of IRF6 Positive_regulation of LTB4R 1 0.01 2.38 0.53 5.00
83 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52 5.00
84 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 5.00
85 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48 5.00
86 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 5.00
87 INT237810 Itpr3 Positive_regulation of Localization of Car2 2 0.08 0.68 0.45 5.00
88 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45 5.00
89 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44 5.00
90 INT318483 Binding of LTB4R and FPR2 1 0.02 0.98 0.42 5.00
91 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42 5.00
92 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42 5.00
93 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41 5.00
94 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 5.00
95 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4 5.00
96 INT221027 ELANE Positive_regulation of IL8 2 0.14 1.3 0.4 5.00
97 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39 5.00
98 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38 5.00
99 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38 5.00
100 INT318489 Positive_regulation of IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38 5.00
101 INT318482 IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38 5.00
102 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 5.00
103 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 5.00
104 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36 5.00
105 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36 5.00
106 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 5.00
107 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 5.00
108 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 5.00
109 INT318484 IRF6 Positive_regulation of Positive_regulation of LTB4R 1 0.01 1.38 0.35 5.00
110 INT288537 Binding of Ccr3 and Ccl11 1 0.17 2.92 0.35 5.00
111 INT318486 IRF6 Positive_regulation of Negative_regulation of FPR2 1 0.10 1.39 0.35 5.00
112 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34 5.00
113 INT353128 Negative_regulation of Binding of TAC1 and B3GAT1 1 0.29 1.95 0.33 5.00
114 INT304320 Binding of Ptger2 and Ptger4 2 0.26 0.06 0.33 5.00
115 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
116 INT226716 Binding of Cxcr4 and Sdf2l1 2 0.30 1.42 0.32 5.00
117 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32 5.00
118 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32 5.00
119 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 5.00
120 INT318480 IRF6 Positive_regulation of Gene_expression of LTB4R 1 0.01 1.63 0.29 5.00
121 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 5.00
122 INT274172 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of TNF 1 0.02 0.72 0.28 5.00
123 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27 5.00
124 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27 5.00
125 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27 5.00
126 INT318477 Regulation of IRF6 Positive_regulation of LTB4R 1 0.00 1 0.27 5.00
127 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27 5.00
128 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27 5.00
129 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27 5.00
130 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27 5.00
131 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26 5.00
132 INT282646 Binding of PROC and PROCR 1 0.40 0.99 0.26 5.00
133 INT282649 Binding of THBD and PROCR 1 0.40 0.97 0.26 5.00
134 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
135 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
136 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
137 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
138 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26 5.00
139 INT186151 Camk4 Regulation of Creb1 2 0.27 1.06 0.25 5.00
140 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25 5.00
141 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25 5.00
142 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25 5.00
143 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25 5.00
144 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25 5.00
145 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25 5.00
146 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24 5.00
147 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24 5.00
148 INT336738 S100a8 Regulation of Gene_expression of Ambp 1 0.02 2.15 0.24 5.00
149 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24 5.00
150 INT202422 IL8 Positive_regulation of Localization of ELANE 1 0.02 0.91 0.24 5.00
151 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
152 INT336893 Epo Regulation of Epc2 1 0.00 0.69 0.23 5.00
153 INT318485 Positive_regulation of IRF6 Positive_regulation of LTB4R 1 0.00 1.03 0.23 5.00
154 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
155 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23 5.00
156 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23 5.00
157 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23 5.00
158 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23 5.00
159 INT208084 Tlr4 Positive_regulation of Eps8l1 1 0.00 0.5 0.23 5.00
160 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 5.00
161 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
162 INT221784 Nlrp1a Positive_regulation of Gene_expression of Crem 1 0.05 0.61 0.22 5.00
163 INT221781 Camk4 Positive_regulation of Mef2d 1 0.28 0.14 0.22 5.00
164 INT328059 IL4 Regulation of FAAH 1 0.25 4.57 0.21 5.00
165 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
166 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21 5.00
167 INT237824 Stim1 Positive_regulation of soc 1 0.26 1.25 0.21 5.00
168 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21 5.00
169 INT318357 Binding of Pmp2 and Adcy3 1 0.06 0.26 0.2 5.00
170 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2 5.00
171 INT318356 Positive_regulation of Binding of Slc10a7 and Adcy3 1 0.17 0.26 0.2 5.00
172 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 5.00
173 INT318358 Positive_regulation of Binding of Pmp2 and Adcy3 1 0.08 0.26 0.2 5.00
174 INT318359 Binding of Slc10a7 and Adcy3 1 0.12 0.26 0.2 5.00
175 INT336739 Binding of S100a8 and Tlr4 1 0.19 1.28 0.2 5.00
176 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2 5.00
177 INT195423 COMT Negative_regulation of GBE1 1 0.00 0.22 0.19 5.00
178 INT244093 Binding of C2 and Arhgap4 3 0.23 0.38 0.19 5.00
179 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19 5.00
180 INT195424 SNRNP70 Negative_regulation of GBE1 1 0.00 0.22 0.19 5.00
181 INT221785 Camk4 Positive_regulation of Atf1 1 0.12 0.14 0.19 5.00
182 INT336892 Positive_regulation of Epc2 Positive_regulation of Localization of Spp1 1 0.00 0.62 0.19 5.00
183 INT336890 Positive_regulation of Epc2 Positive_regulation of Spp1 1 0.00 0.62 0.19 5.00
184 INT304325 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of VEGFA 1 0.25 0.23 0.19 5.00
185 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18 5.00
186 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
187 INT316129 Binding of HLA-DRA and IL10 1 0.12 3.1 0.17 5.00
188 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17 5.00
189 INT274169 Mapk1 Regulation of Pde4a 1 0.05 0.62 0.17 5.00
190 INT316132 IL10 Regulation of MARCH1 1 0.11 2.12 0.17 5.00
191 INT316122 IL10 Regulation of Gene_expression of MARCH1 1 0.19 2.12 0.17 5.00
192 INT326048 Gtf3a Positive_regulation of Positive_regulation of Csf2 1 0.04 0.5 0.16 5.00
193 INT316123 Binding of HLA-DRA and BCAR1 1 0.02 0.48 0.16 5.00
194 INT208083 Binding of Arid3b and Eps8l1 1 0.01 0.4 0.16 5.00
195 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
196 INT316124 TLR2 Positive_regulation of Gene_expression of HLA-DRA 1 0.14 0.34 0.16 5.00
197 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16 5.00
198 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
199 INT312572 AMBP Negative_regulation of Gene_expression of IL6 1 0.11 0.66 0.14 5.00
200 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Versed. They are ordered first by their pain relevance and then by number of times they were reported in Versed. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
2 INT10835 Regulation of IL8 79 0.49 53.04 24.14 100.00
3 INT132314 Positive_regulation of Gabra5 9 0.65 1.45 4.4 100.00
4 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 100.00
5 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
7 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
8 INT163859 Negative_regulation of Gene_expression of Tspo 1 0.41 0.17 0.64 100.00
9 INT163853 Negative_regulation of Gene_expression of Cyp11a1 1 0.32 0.17 0.64 100.00
10 INT163851 Negative_regulation of Gene_expression of Hsd3b1 1 0.41 0.17 0.64 100.00
11 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47 100.00
12 INT12333 Regulation of CYP3A 18 0.62 2.25 6.74 100.00
13 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 100.00
14 INT135983 Positive_regulation of Gene_expression of Gabra5 1 0.43 0 1.81 100.00
15 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 100.00
16 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
17 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 100.00
18 INT46055 Regulation of Gene_expression of Decr1 5 0.06 1.91 3.4 100.00
19 INT69943 Regulation of Gene_expression of Nqo1 3 0.26 0.98 3.56 100.00
20 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
21 INT123740 Localization of Pbr 1 0.27 0.18 0.69 100.00
22 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
23 INT2791 Regulation of Mb 53 0.61 23.03 10.73 100.00
24 INT14258 Regulation of TSPO 32 0.60 10.16 6.24 100.00
25 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
26 INT49538 Binding of Gria1 22 0.47 2.66 13.35 100.00
27 INT94925 Regulation of Gene_expression of Grip2 7 0.55 4.23 3.18 100.00
28 INT27590 Negative_regulation of Phex 5 0.36 2.38 2.26 100.00
29 INT9578 Regulation of Binding of Adarb1 4 0.09 0.21 3.37 100.00
30 INT14257 Localization of TSPO 9 0.73 1.48 1.87 100.00
31 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02 100.00
32 INT17145 Binding of Cyp2c22 19 0.42 1.39 6.8 100.00
33 INT165277 Negative_regulation of Acsf2 8 0.36 1.99 3.79 100.00
34 INT153865 Gene_expression of Cyp2d 5 0.51 1.56 2.28 100.00
35 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 100.00
36 INT36199 Regulation of SERPINA7 1 0.12 0 0.86 100.00
37 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 100.00
38 INT73802 Regulation of Selp 17 0.60 8.72 3.51 100.00
39 INT54295 Negative_regulation of Localization of Spnb4 2 0.57 0 2.21 100.00
40 INT31096 Binding of HRH2 7 0.37 2 2 100.00
41 INT124623 Binding of GDF15 4 0.35 2.06 1.09 100.00
42 INT149758 Binding of Coro1a 2 0.36 0.61 0.05 100.00
43 INT4651 Gene_expression of Cebpz 39 0.00 20.19 8.5 99.98
44 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99 99.98
45 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 99.98
46 INT51281 Gene_expression of Cyp2c29 4 0.54 0.96 0.74 99.96
47 INT46057 Gene_expression of Cyb5 2 0.55 0.16 1.26 99.94
48 INT251917 Negative_regulation of Gene_expression of Cyb5 1 0.34 0 0.17 99.94
49 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.92
50 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.92
51 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.92
52 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 99.92
53 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 99.92
54 INT53217 Positive_regulation of Gene_expression of Decr1 5 0.06 1.85 3.51 99.92
55 INT89229 Positive_regulation of Gene_expression of Nqo1 2 0.06 0.1 2.81 99.92
56 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48 99.92
57 INT83490 Regulation of Binding of Htr5b 1 0.20 0.13 0.83 99.92
58 INT25745 Regulation of Tspo 6 0.45 0.25 3.1 99.92
59 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 99.90
60 INT59793 Regulation of Gene_expression of STH 2 0.44 0.88 0.51 99.90
61 INT1782 Regulation of Gh1 125 0.62 22 55.74 99.90
62 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98 99.90
63 INT18505 Negative_regulation of Coro1a 4 0.57 0.9 0.26 99.88
64 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.86
65 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49 99.84
66 INT163861 Positive_regulation of Gene_expression of Cyp11a1 2 0.38 0.64 1.53 99.84
67 INT163850 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0.17 0.61 99.84
68 INT46640 Negative_regulation of Cebpz 9 0.37 2.67 1.52 99.82
69 INT4806 Localization of TPSAB1 29 0.80 5.05 10.52 99.82
70 INT96724 Gene_expression of Cyp3a11 10 0.77 4.82 7.76 99.82
71 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 99.78
72 INT234 Binding of Alb 151 0.48 52.34 32.97 99.78
73 INT54294 Localization of Spnb4 9 0.78 0 18.64 99.76
74 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.76
75 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 99.76
76 INT15357 Positive_regulation of STH 7 0.49 4.55 1.6 99.76
77 INT161252 Positive_regulation of GAD2 2 0.49 0.08 0.63 99.76
78 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.74
79 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.70
80 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 99.68
81 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.68
82 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 99.68
83 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.68
84 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.66
85 INT28782 Negative_regulation of Slc43a3 13 0.35 5.02 5.01 99.66
86 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 99.62
87 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23 99.62
88 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 99.60
89 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.58
90 INT46054 Gene_expression of Decr1 39 0.65 12.82 9.48 99.58
91 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 99.58
92 INT41627 Gene_expression of Nqo1 33 0.65 4.58 10.48 99.58
93 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 99.56
94 INT2613 Negative_regulation of Positive_regulation of Ren 16 0.59 8.2 5.62 99.56
95 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 99.56
96 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01 99.56
97 INT200873 Positive_regulation of Negative_regulation of Gopc 4 0.36 0.81 1.59 99.54
98 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54 99.52
99 INT155983 Gene_expression of Cyp11a1 7 0.58 2.6 3.38 99.52
100 INT163852 Gene_expression of Hsd3b1 1 0.75 0.45 1.36 99.52
101 INT163857 Gene_expression of Dlc1 1 0.03 0.17 0.6 99.52
102 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 99.48
103 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 99.46
104 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.46
105 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65 99.46
106 INT12334 Positive_regulation of CYP3A 34 0.70 6.77 7.85 99.46
107 INT12563 Localization of Mpo 33 0.81 20.99 9.58 99.44
108 INT2790 Regulation of Gene_expression of Mb 7 0.61 1.61 1.39 99.40
109 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.40
110 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.40
111 INT83489 Binding of Htr5b 3 0.36 0.48 1.88 99.36
112 INT251915 Positive_regulation of Igkv4-69 1 0.09 0 0.17 99.36
113 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45 99.36
114 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31 99.36
115 INT182106 Localization of PDLIM4 1 0.73 0.26 0.09 99.36
116 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.34
117 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 99.32
118 INT48 Positive_regulation of Localization of Ren 69 0.70 12.47 18.03 99.32
119 INT3579 Localization of Oxt 555 0.81 43.35 292.44 99.30
120 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 99.28
121 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33 99.28
122 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.28
123 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05 99.28
124 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.26
125 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 99.26
126 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 99.26
127 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.24
128 INT5573 Negative_regulation of Gene_expression of Penk 113 0.59 21.83 64.66 99.24
129 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 99.24
130 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44 99.22
131 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67 99.22
132 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 99.20
133 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.18
134 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04 99.16
135 INT46 Localization of Ren 233 0.81 46.15 62.44 99.16
136 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 99.16
137 INT112267 Positive_regulation of Rgc32 10 0.39 8.1 2.09 99.14
138 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.10
139 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 99.08
140 INT96536 Protein_catabolism of Gip 1 0.64 0 0.15 99.06
141 INT73434 Negative_regulation of Nppa 8 0.35 3.86 4.31 99.04
142 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 99.04
143 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.04
144 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 99.04
145 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.04
146 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3 99.02
147 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98 99.00
148 INT52107 Transcription of IL8 63 0.72 41.66 16.06 99.00
149 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13 98.98
150 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 98.96
151 INT50580 Binding of PPIG 39 0.36 11.17 12.34 98.92
152 INT7028 Localization of Pdyn 90 0.81 8.89 73.54 98.90
153 INT2212 Binding of Abat 89 0.48 18.36 63.99 98.90
154 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 98.88
155 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 98.86
156 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96 98.86
157 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42 98.86
158 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 98.82
159 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 98.78
160 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 98.74
161 INT102083 Gene_expression of Gabra5 10 0.72 0.31 4.63 98.68
162 INT12770 Negative_regulation of Positive_regulation of IKBKG 7 0.56 0.34 3.02 98.68
163 INT19109 Positive_regulation of CYP3A5 7 0.67 1.48 1.51 98.68
164 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 98.66
165 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59 98.64
166 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 98.64
167 INT49189 Regulation of Chrna6 4 0.45 1.23 2.63 98.60
168 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 98.56
169 INT6437 Binding of YY1 154 0.47 26.3 90.46 98.54
170 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 98.52
171 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.50
172 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.50
173 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02 98.46
174 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 98.44
175 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 98.44
176 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 98.38
177 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 98.34
178 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52 98.28
179 INT22579 Localization of Efs 35 0.65 2.77 16.05 98.24
180 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51 98.08
181 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 98.08
182 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 98.08
183 INT9210 Regulation of IL6 166 0.62 125.61 49.95 97.96
184 INT182105 Gene_expression of PDLIM4 1 0.65 0.26 0.09 97.88
185 INT5489 Localization of CA2 172 0.80 39.46 33.56 97.80
186 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 97.80
187 INT3439 Localization of Abat 1017 0.78 112.39 727.06 97.78
188 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 97.76
189 INT135982 Positive_regulation of Positive_regulation of Gabra5 1 0.47 0 1.35 97.60
190 INT163858 Regulation of Gene_expression of Cyp11a1 1 0.46 0.55 1.53 97.56
191 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 97.52
192 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27 97.44
193 INT163860 Regulation of Gene_expression of Hsd3b1 1 0.44 0.28 0.76 97.42
194 INT18088 Binding of Tspo 26 0.48 9.12 10.2 97.28
195 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12 97.24
196 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 97.12
197 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 97.04
198 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 96.96
199 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 96.96
200 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 96.96
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