P:adenocard

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pChart

Pain Term
Category Drug
Synonyms Adenosine
Pain Specific No
Documents 4106
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for adenocard. They are ordered first by their pain relevance and then by number of times they were reported for adenocard. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT81228 Negative_regulation of Adk Positive_regulation of Ado 1 0.04 0.26 0.59 100.00
2 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62 100.00
3 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 100.00
4 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79 100.00
5 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93 100.00
6 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82 100.00
7 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82 100.00
8 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12 100.00
9 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92 100.00
10 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64 100.00
11 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9 100.00
12 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9 100.00
13 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21 100.00
14 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89 100.00
15 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89 100.00
16 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77 100.00
17 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54 100.00
18 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32 100.00
19 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32 100.00
20 INT252426 Binding of SLURP1 and Negative_regulation of Gene_expression of TNF 1 0.01 1.13 0.49 100.00
21 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83 100.00
22 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23 100.00
23 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47 100.00
24 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64 100.00
25 INT353698 NA Positive_regulation of Atp6v0a1 1 0.00 0.67 0.44 100.00
26 INT149358 Binding of Oprm1 and Positive_regulation of Positive_regulation of Npr1 1 0.00 0.09 0.26 100.00
27 INT346526 Binding of ADORA1 and PTH1R 1 0.01 0 0.1 100.00
28 INT31942 Binding of FCGR1A and Oprd1 1 0.00 0 0.62 100.00
29 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4 100.00
30 INT216737 Binding of ADORA2B and TCFL5 1 0.03 0.05 0.39 100.00
31 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88 100.00
32 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86 100.00
33 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5 100.00
34 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31 100.00
35 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25 100.00
36 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2 100.00
37 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2 100.00
38 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2 100.00
39 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13 100.00
40 INT270664 Ensa Positive_regulation of Localization of Ins1 1 0.02 0.89 0.05 100.00
41 INT346529 Binding of PTH1R and TACR1 1 0.00 0 0.05 100.00
42 INT172698 Ugt1a6 Negative_regulation of Localization of Acot1 1 0.01 0 0.68 99.98
43 INT54543 DBP Regulation of PENK 1 0.28 0 0.12 99.98
44 INT71395 Ugt2a2 Regulation of Bcl2a1a 1 0.00 0.1 1.32 99.96
45 INT102086 TRNAI1 Negative_regulation of Positive_regulation of P2rx3 1 0.00 0.47 0.74 99.90
46 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12 99.88
47 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47 99.78
48 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 99.76
49 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42 99.76
50 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24 99.76
51 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37 99.74
52 INT143662 Rere Regulation of Gpx1 1 0.69 0.56 0.12 99.72
53 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05 99.72
54 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55 99.64
55 INT56700 Penk Regulation of FER 1 0.00 0 0.59 99.58
56 INT346523 Binding of PTH1R and RHO 1 0.01 0 0.05 99.52
57 INT9824 Binding of Agtr2 and Bcl2a1a 1 0.16 0.24 0.64 99.48
58 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22 99.28
59 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78 99.24
60 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56 99.22
61 INT54544 CREB1 Regulation of PENK 1 0.59 0 0.12 99.20
62 INT54545 Binding of CREB1 and PENK 1 0.35 0 0.12 99.20
63 INT112796 IL4I1 Positive_regulation of Gene_expression of CCL2 1 0.07 0 0.23 99.08
64 INT112801 IL4I1 Positive_regulation of CCL2 1 0.03 0 0.23 99.08
65 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 99.08
66 INT35690 Dpp6 Regulation of Jmjd1c 1 0.17 0 0.33 99.04
67 INT171678 PPY Regulation of CISD1 1 0.00 0.33 0.33 99.04
68 INT171679 PPY Regulation of PRKCA 1 0.08 0.33 0.33 99.04
69 INT171680 PPY Regulation of MAPK4 1 0.02 0.33 0.33 99.04
70 INT342887 Binding of IFNG and IFNGR1 1 0.02 0.65 0.05 99.02
71 INT252455 Binding of Adora2b and SLURP1 1 0.02 0.6 0.81 98.88
72 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35 98.88
73 INT92182 Mir702 Negative_regulation of Adk 1 0.07 1.29 2.47 98.68
74 INT165171 Tpsab1 Positive_regulation of Gene_expression of P2RX4 1 0.02 0.47 0.28 98.68
75 INT215630 Fig4 Regulation of Npy 1 0.01 0.26 0.76 98.48
76 INT215655 Fig4 Regulation of REG1A 1 0.00 0.13 0.38 98.48
77 INT216738 Binding of ATP6V0A1 and TCFL5 1 0.01 0.06 0.38 98.44
78 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5 98.40
79 INT32782 Binding of Vip and Elane 1 0.17 0 0.61 98.36
80 INT174892 Binding of ADRB3 and ENPP3 1 0.04 0.4 0.14 98.32
81 INT112660 TNF Regulation of Tnf 1 0.02 0.94 0.08 98.28
82 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 98.24
83 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18 97.88
84 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18 97.88
85 INT254121 Binding of Tbce and Aliq1 1 0.00 0.69 0.2 97.40
86 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68 97.40
87 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 97.36
88 INT254123 Binding of Adora2b and Rai1 1 0.24 0.75 0.35 97.24
89 INT112804 IL4I1 Positive_regulation of Positive_regulation of MAPK1 1 0.03 0 0.22 97.24
90 INT112793 IL4I1 Positive_regulation of Positive_regulation of MAPK14 1 0.04 0 0.22 97.24
91 INT112802 IL4I1 Positive_regulation of Positive_regulation of MAPK8 1 0.04 0 0.22 97.24
92 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85 97.20
93 INT239500 Binding of Aes and Atic 1 0.20 0.4 0.56 97.16
94 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8 96.96
95 INT193562 Nr1i3 Positive_regulation of Hspg2 1 0.00 0 0.17 96.76
96 INT78368 IGKV2D-29 Positive_regulation of PKIB 1 0.07 0.26 0.35 96.56
97 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16 96.52
98 INT226373 IL19 Positive_regulation of Gene_expression of IL5 1 0.02 0.56 0.2 96.24
99 INT226336 IL19 Positive_regulation of Gene_expression of IL13 1 0.01 0.56 0.2 96.24
100 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2 96.24
101 INT226353 IL19 Positive_regulation of Gene_expression of IL4 1 0.03 0.56 0.2 96.24
102 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43 96.00
103 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67 95.80
104 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14 95.80
105 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99 95.76
106 INT149357 Trib3 Negative_regulation of Raf1 1 0.01 0.08 0.25 95.60
107 INT75989 Regulation of RICTOR Positive_regulation of IK 1 0.00 0.15 0.27 95.48
108 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31 95.48
109 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 95.44
110 INT113992 Binding of HRH1 and LIAS 1 0.00 0.09 0.38 95.40
111 INT226377 IL19 Positive_regulation of IL13 1 0.01 0.56 0.2 95.36
112 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1 95.34
113 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46 95.20
114 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3 95.20
115 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3 95.20
116 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3 95.20
117 INT149356 Prkaca Negative_regulation of Raf1 1 0.10 0.08 0.25 95.20
118 INT76761 Kctd1 Negative_regulation of RFFL 1 0.00 0.5 0.63 95.20
119 INT75988 RICTOR Positive_regulation of IK 1 0.00 0.15 0.27 95.04
120 INT113500 IL1B Positive_regulation of Gene_expression of BHLHE23 1 0.18 0.1 0.71 94.96
121 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71 94.96
122 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05 94.92
123 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55 94.84
124 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62 94.64
125 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2 94.60
126 INT309725 Gene_expression of CALM3 Negative_regulation of Positive_regulation of TRPC6 1 0.07 0 0.1 94.60
127 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85 94.48
128 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2 94.48
129 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29 94.32
130 INT226379 IL19 Positive_regulation of IL5 1 0.02 0.55 0.2 93.92
131 INT63490 Negative_regulation of Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51 93.80
132 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29 93.64
133 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33 93.64
134 INT309743 Binding of CA2 and CALM3 1 0.04 0 0.13 93.60
135 INT63489 Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51 93.48
136 INT226369 IL19 Positive_regulation of IL4 1 0.03 0.55 0.2 93.44
137 INT326472 AGXT Negative_regulation of PGAP1 1 0.00 0.05 0.39 93.40
138 INT105809 ATP8A2 Positive_regulation of P2RX2 1 0.13 0.11 0.7 93.36
139 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19 93.12
140 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43 93.08
141 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84 92.92
142 INT299460 Foxl2 Positive_regulation of Tpr 1 0.01 0.56 0.05 92.88
143 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19 92.80
144 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 92.68
145 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18 92.64
146 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18 92.64
147 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02 92.24
148 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29 92.24
149 INT215629 Binding of Kcnj5 and Fig4 1 0.00 0.37 0.39 91.84
150 INT299457 Foxl2 Positive_regulation of Gnrhr 1 0.42 0.56 0.05 91.76
151 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43 91.64
152 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92 91.48
153 INT106893 Ptpn2 Positive_regulation of Tac1 1 0.02 2.02 0.29 91.04
154 INT271002 Binding of LTC4S and Aia1 1 0.00 0.98 0.12 90.96
155 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76 90.68
156 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61 89.88
157 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51 89.56
158 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75 89.48
159 INT309751 Binding of CA2 and TRPV4 1 0.08 0 0.23 89.48
160 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 89.42
161 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 89.42
162 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27 89.20
163 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 89.12
164 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67 88.48
165 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75 88.48
166 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18 88.24
167 INT112659 Cpox Positive_regulation of Gene_expression of TNF 1 0.01 0.79 0.52 88.04
168 INT112661 Cpox Positive_regulation of Localization of TNF 1 0.01 0.79 0.52 88.04
169 INT216841 TCIRG1 Negative_regulation of ADCY1 1 0.01 0.35 0.18 87.96
170 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.74 87.92
171 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23 87.76
172 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 87.52
173 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86 87.36
174 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41 87.36
175 INT326473 Positive_regulation of PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.41 87.12
176 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22 86.96
177 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 86.92
178 INT32662 Hps1 Negative_regulation of Localization of CGB 1 0.00 0 0.46 86.88
179 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28 86.84
180 INT326470 PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.4 86.80
181 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23 86.64
182 INT43543 SH3RF3 Negative_regulation of DNAH8 1 0.03 0.27 0.14 86.64
183 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78 86.08
184 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.64 85.84
185 INT50826 RLN1 Positive_regulation of PIRT 1 0.01 0.1 0.22 85.84
186 INT52702 Capza2 Positive_regulation of Ptgs2 1 0.00 0.27 0.11 85.84
187 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48 85.80
188 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11 85.60
189 INT52701 Slc3a1 Positive_regulation of Ptgs2 1 0.06 0.27 0.11 85.28
190 INT50827 RLN1 Positive_regulation of CSN3 1 0.28 0.1 0.22 85.12
191 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 85.04
192 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15 84.60
193 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44 84.56
194 INT138332 Binding of P2rx3 and F2rl1 1 0.35 0.25 0.59 84.44
195 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11 84.24
196 INT125550 FGFR1 Negative_regulation of Cyp2e1 1 0.02 0.06 0.18 83.80
197 INT25721 Negative_regulation of Npy Negative_regulation of Avp 1 0.48 0.1 0.21 83.80
198 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 83.44
199 INT25720 Npy Negative_regulation of Avp 1 0.48 0.1 0.21 83.40
200 INT163760 Ifng Positive_regulation of Phosphorylation of Stat1 1 0.12 0.08 0.23 83.28

Single Events

The table below shows the top 200 pain related interactions that have been reported for adenocard. They are ordered first by their pain relevance and then by number of times they were reported in adenocard. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38 100.00
2 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6 100.00
3 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 100.00
4 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87 100.00
5 INT11568 Gene_expression of ADORA2A 14 0.73 1.51 7.79 100.00
6 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17 100.00
7 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89 100.00
8 INT35307 Regulation of Adk 11 0.35 3.21 7.79 100.00
9 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36 100.00
10 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07 100.00
11 INT142694 Positive_regulation of PGAP1 3 0.08 2.78 8.68 100.00
12 INT65661 Positive_regulation of Ado 13 0.52 4.75 8.54 100.00
13 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93 100.00
14 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01 100.00
15 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 100.00
16 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78 100.00
17 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85 100.00
18 INT19155 Binding of Adora1 25 0.47 6.41 10.72 100.00
19 INT74161 Positive_regulation of Negative_regulation of Adk 10 0.50 3.3 6.77 100.00
20 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 100.00
21 INT63781 Regulation of Ado 8 0.34 3.78 5.19 100.00
22 INT78371 Gene_expression of IGKV2D-29 29 0.75 6.95 7.66 100.00
23 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25 100.00
24 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63 100.00
25 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24 100.00
26 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 100.00
27 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75 100.00
28 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13 100.00
29 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 100.00
30 INT81226 Gene_expression of Adk 9 0.64 9.28 4.81 100.00
31 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47 100.00
32 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36 100.00
33 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79 100.00
34 INT70252 Gene_expression of Ugt1a6 20 0.77 3.89 7.45 100.00
35 INT36256 Regulation of Ada 9 0.62 4.99 5.07 100.00
36 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69 100.00
37 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7 100.00
38 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 100.00
39 INT23209 Binding of Adora2a 17 0.38 2.04 8.35 100.00
40 INT92186 Binding of SLURP1 13 0.36 4.21 5.77 100.00
41 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13 100.00
42 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 100.00
43 INT216754 Binding of ATP6V0A1 5 0.11 0.71 4.98 100.00
44 INT63779 Localization of Ado 6 0.64 4.8 3.81 100.00
45 INT101699 Regulation of Adora1 14 0.61 3.7 7.59 100.00
46 INT77213 Transcription of ADORA2A 1 0.69 0 2.55 100.00
47 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 100.00
48 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
49 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06 100.00
50 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75 100.00
51 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 100.00
52 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73 100.00
53 INT216840 Binding of Adora2b 3 0.47 5.23 4.85 100.00
54 INT2066 Localization of Agt 56 0.80 9.95 16.25 100.00
55 INT83014 Binding of Adora2a 13 0.48 5.57 5.33 100.00
56 INT9167 Binding of Adora1 6 0.40 0.53 6.9 100.00
57 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17 100.00
58 INT216851 Binding of IGKV2D-29 8 0.36 1.56 3.93 100.00
59 INT52878 Positive_regulation of ATP6V0A1 9 0.54 1.35 2.92 100.00
60 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71 100.00
61 INT21465 Positive_regulation of Epha1 5 0.48 0.69 4.4 100.00
62 INT6943 Positive_regulation of Gabrd 71 0.70 17.36 35.25 100.00
63 INT63780 Positive_regulation of Localization of Ado 3 0.32 2.79 2.29 100.00
64 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66 100.00
65 INT84811 Gene_expression of Ado 6 0.51 2.65 2.74 100.00
66 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
67 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
68 INT4850 Binding of Tac1 57 0.47 14.25 42.17 100.00
69 INT29229 Regulation of NCOR2 20 0.42 5.75 8.08 100.00
70 INT7134 Localization of KNG1 127 0.79 65.73 67.97 100.00
71 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64 100.00
72 INT101477 Binding of ADORA1 8 0.31 0.42 3.07 100.00
73 INT9765 Positive_regulation of Adk 2 0.48 0.35 4.07 100.00
74 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41 100.00
75 INT34604 Binding of Ada 11 0.31 4.15 3.1 100.00
76 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09 100.00
77 INT54178 Regulation of Adora1 5 0.39 0.29 2.85 100.00
78 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67 100.00
79 INT92181 Negative_regulation of Mir702 1 0.10 1.14 2.48 100.00
80 INT13664 Positive_regulation of Localization of Adk 1 0.40 1.87 1.39 100.00
81 INT12632 Negative_regulation of Binding of INSRR 13 0.38 6.54 6.39 100.00
82 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
83 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84 100.00
84 INT13665 Localization of Adk 1 0.61 2.16 1.37 100.00
85 INT49768 Positive_regulation of Kcnj5 58 0.41 11.89 16.02 100.00
86 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 100.00
87 INT34605 Localization of Ada 7 0.80 0.13 1.61 100.00
88 INT224046 Negative_regulation of Adora2b 9 0.43 4 3.6 100.00
89 INT81224 Negative_regulation of Ado 3 0.29 1.28 1.46 100.00
90 INT78808 Regulation of ADK 1 0.30 0 1.19 100.00
91 INT9822 Binding of Agtr2 9 0.36 3 3.93 100.00
92 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
93 INT84812 Negative_regulation of Positive_regulation of Ado 1 0.33 0.55 1.81 100.00
94 INT45065 Gene_expression of Ado 3 0.54 2.34 1.55 100.00
95 INT1251 Positive_regulation of Dut 9 0.13 0.73 2.48 100.00
96 INT54181 Regulation of Epha2 2 0.09 0.36 2.06 100.00
97 INT56122 Positive_regulation of Abcc3 7 0.47 2.25 4.9 100.00
98 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89 100.00
99 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95 100.00
100 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 100.00
101 INT52523 Positive_regulation of Adora3 2 0.49 1.39 1.79 100.00
102 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 100.00
103 INT92180 Positive_regulation of Negative_regulation of Adk 1 0.33 0.73 1.49 100.00
104 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16 100.00
105 INT134590 Localization of ADA 7 0.65 8.43 3.96 100.00
106 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75 100.00
107 INT216850 Binding of TCIRG1 3 0.10 0.44 1.37 100.00
108 INT45067 Negative_regulation of Ado 4 0.34 1.51 1.15 100.00
109 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
110 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33 100.00
111 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07 100.00
112 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 100.00
113 INT48747 Positive_regulation of Dbp 7 0.24 1.28 4.69 100.00
114 INT29046 Positive_regulation of Etf1 32 0.12 12.03 21.06 100.00
115 INT111385 Negative_regulation of Adora3 7 0.43 3.91 2.8 100.00
116 INT80550 Positive_regulation of Gene_expression of Asap1 8 0.42 5.8 3.09 100.00
117 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
118 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82 100.00
119 INT131494 Regulation of ADA 8 0.52 7.37 2.97 100.00
120 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66 100.00
121 INT14357 Positive_regulation of FCGR1A 10 0.44 7.14 5.4 100.00
122 INT119125 Regulation of ADORA2A 2 0.31 0 1.01 100.00
123 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 100.00
124 INT26579 Regulation of RICTOR 2 0.23 0.09 1.51 100.00
125 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18 100.00
126 INT34413 Negative_regulation of Pia1 4 0.12 0.24 2.17 100.00
127 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67 100.00
128 INT124683 Gene_expression of Pia8 3 0.41 2.17 7.11 100.00
129 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99 100.00
130 INT84814 Positive_regulation of Gene_expression of Ado 1 0.38 0.34 0.96 100.00
131 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 100.00
132 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69 100.00
133 INT17561 Localization of Car2 303 0.79 60.95 44.52 100.00
134 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 100.00
135 INT173693 Localization of Gopc 249 0.65 70.49 38.81 100.00
136 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 100.00
137 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73 100.00
138 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08 100.00
139 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02 100.00
140 INT1250 Positive_regulation of Positive_regulation of Dut 6 0.09 0.41 1.7 100.00
141 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
142 INT216749 Positive_regulation of ADORA2B 6 0.37 0.89 1.72 100.00
143 INT68200 Protein_catabolism of Ada 2 0.44 0.68 0.83 100.00
144 INT89048 Gene_expression of P2RX2 28 0.75 8.75 7.9 100.00
145 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37 100.00
146 INT30277 Protein_catabolism of Ada 3 0.52 0.9 1.42 100.00
147 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26 100.00
148 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86 100.00
149 INT137927 Positive_regulation of Positive_regulation of Ada 1 0.03 1.31 1.47 100.00
150 INT92880 Localization of ADORA1 2 0.80 0.09 0.84 100.00
151 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
152 INT59 Regulation of Adrb1 25 0.42 8.32 9.78 100.00
153 INT78823 Negative_regulation of SLURP1 6 0.24 2.22 1.79 100.00
154 INT167716 Negative_regulation of Gene_expression of Gnrhr 2 0.35 6.64 0.93 100.00
155 INT299420 Negative_regulation of Gene_expression of Star 1 0.33 6.66 0.5 100.00
156 INT216849 Binding of ADORA2A 2 0.05 0 1.11 100.00
157 INT21464 Positive_regulation of Binding of Epha1 2 0.58 0.44 1.06 100.00
158 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 100.00
159 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14 100.00
160 INT54435 Binding of Sptan1 8 0.36 4.7 2.44 100.00
161 INT134717 Positive_regulation of Rs1 2 0.07 3.71 2.31 100.00
162 INT216735 Gene_expression of Matn1 2 0.65 1.68 0.72 100.00
163 INT291035 Regulation of Gene_expression of Ado 1 0.08 1.35 0.74 100.00
164 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
165 INT64878 Positive_regulation of Lpar6 3 0.20 0.89 1.9 100.00
166 INT84810 Positive_regulation of Positive_regulation of Ado 2 0.35 0.36 0.9 100.00
167 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55 100.00
168 INT61924 Binding of Adk 1 0.17 0.1 0.72 100.00
169 INT12849 Negative_regulation of Atp6v0a1 5 0.51 0.64 1.89 100.00
170 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16 100.00
171 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64 100.00
172 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 100.00
173 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17 100.00
174 INT119124 Positive_regulation of ADORA2A 4 0.35 0.96 1.14 100.00
175 INT143682 Negative_regulation of Gene_expression of Ada 2 0.54 0.28 0.44 100.00
176 INT143683 Negative_regulation of Gene_expression of ADA 1 0.09 0.28 0.44 100.00
177 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96 100.00
178 INT216750 Positive_regulation of Gene_expression of ADORA2B 1 0.34 0 0.64 100.00
179 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4 100.00
180 INT216761 Positive_regulation of Binding of ADORA2B 1 0.34 0 0.63 100.00
181 INT194851 Protein_catabolism of Adora2b 1 0.17 0.6 0.75 100.00
182 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75 100.00
183 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 100.00
184 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04 100.00
185 INT92189 Positive_regulation of Slurp1 4 0.18 1.84 3.01 100.00
186 INT52524 Regulation of Adora3 3 0.44 1.17 0.96 100.00
187 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 100.00
188 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06 100.00
189 INT11490 Binding of KCNMA1 13 0.37 3.61 3.32 100.00
190 INT2212 Binding of Abat 89 0.48 18.36 63.99 100.00
191 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 100.00
192 INT89008 Gene_expression of Lepr 2 0.65 5.39 1.66 100.00
193 INT81225 Binding of Ado 1 0.25 0.26 0.44 100.00
194 INT92183 Negative_regulation of Olr702 1 0.26 2.31 2.71 100.00
195 INT76198 Positive_regulation of ADORA3 3 0.45 1.53 1.7 100.00
196 INT88518 Negative_regulation of Positive_regulation of INSRR 4 0.27 2.26 1.86 100.00
197 INT274341 Positive_regulation of Gene_expression of Epha1 1 0.01 0 0.46 100.00
198 INT99844 Localization of P2ry1 7 0.74 4.05 2.19 100.00
199 INT9012 Localization of Vip 283 0.81 31.71 106.16 100.00
200 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 100.00
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