P:agonist

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pChart

Pain Term
Category Family
Synonyms Agonists
Pain Specific No
Documents 25045
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for agonist. They are ordered first by their pain relevance and then by number of times they were reported for agonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 100.00
2 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 100.00
3 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 100.00
4 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99 100.00
5 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18 100.00
6 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2 100.00
7 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63 100.00
8 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24 100.00
9 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75 100.00
10 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56 100.00
11 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 100.00
12 INT138777 Binding of Galr2 and Galr1 1 0.08 1.18 1.64 100.00
13 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 100.00
14 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91 100.00
15 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 100.00
16 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57 100.00
17 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58 100.00
18 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95 100.00
19 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32 100.00
20 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 100.00
21 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 100.00
22 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 100.00
23 INT81832 Binding of ADRA2C and CRYGS 1 0.06 0 0.66 100.00
24 INT264803 Binding of CNNM2 and ZNF343 1 0.00 0.18 0.31 100.00
25 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89 100.00
26 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 100.00
27 INT264804 Binding of CNNM2 and GOPC 1 0.00 0.18 0.3 100.00
28 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7 100.00
29 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33 100.00
30 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 100.00
31 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 100.00
32 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79 100.00
33 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4 100.00
34 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 100.00
35 INT139957 Binding of Man1b-rs and Gprasp1 1 0.00 0.08 0.85 100.00
36 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 0.00 0 1.25 100.00
37 INT69173 Avp Positive_regulation of Oxt 1 0.18 0 0.42 100.00
38 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53 100.00
39 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28 100.00
40 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23 100.00
41 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 100.00
42 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 100.00
43 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29 100.00
44 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29 100.00
45 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29 100.00
46 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77 100.00
47 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28 100.00
48 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24 100.00
49 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45 100.00
50 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12 100.00
51 INT26648 Binding of CEL and HP 1 0.04 0 0.58 100.00
52 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69 100.00
53 INT246688 exf Negative_regulation of Gene_expression of Ros1 1 0.01 0.43 0.25 100.00
54 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67 100.00
55 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23 100.00
56 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23 100.00
57 INT246684 exf Regulation of Gene_expression of Ros1 1 0.00 0.42 0.22 100.00
58 INT55564 Binding of Oprk1 and Pde6b 1 0.01 0 0.92 100.00
59 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71 100.00
60 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65 100.00
61 INT135500 Positive_regulation of YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52 100.00
62 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67 100.00
63 INT134287 PLD2 Regulation of Regulation of MRGPRX1 1 0.31 0 0.67 100.00
64 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27 100.00
65 INT246690 exf Regulation of Localization of Ide 1 0.00 0.17 0.3 100.00
66 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96 100.00
67 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96 100.00
68 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29 100.00
69 INT46645 Binding of Gabrg1 and Chrm5 1 0.29 0.09 1 100.00
70 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92 100.00
71 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92 100.00
72 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66 100.00
73 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54 100.00
74 INT96462 Pnoc Positive_regulation of Pag1 1 0.01 0.74 2.45 100.00
75 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39 100.00
76 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34 100.00
77 INT227566 NR3C1 Positive_regulation of RS1 1 0.01 0 0.4 100.00
78 INT227568 NR3C1 Positive_regulation of HTR1A 1 0.00 0 0.4 100.00
79 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93 100.00
80 INT34740 BID Regulation of Gene_expression of PLOD1 1 0.01 0 0.83 100.00
81 INT86960 ADRA1D Negative_regulation of Prl 1 0.00 0 0.97 100.00
82 INT34472 Penk Regulation of Slc3a1 2 0.03 0.42 1.74 100.00
83 INT188922 Binding of Pc and Nr1i2 1 0.11 0 0.19 100.00
84 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19 100.00
85 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92 100.00
86 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02 100.00
87 INT31808 Fam13a Negative_regulation of Oxt 1 0.07 0 0.6 100.00
88 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74 100.00
89 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74 100.00
90 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 0.08 0 0.41 100.00
91 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3 100.00
92 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86 100.00
93 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45 100.00
94 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 100.00
95 INT59396 Tead1 Negative_regulation of Negative_regulation of Man2a2 1 0.00 0 0.86 100.00
96 INT57824 Binding of Trim13 and Slc25a2 1 0.01 0.08 1.19 100.00
97 INT59395 Tead1 Negative_regulation of Man2a2 1 0.00 0 0.86 100.00
98 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84 100.00
99 INT57822 Binding of Slc25a2 and Atxn2l 1 0.00 0.08 1.17 100.00
100 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 100.00
101 INT115800 Positive_regulation of HRASLS Positive_regulation of Positive_regulation of OPRM1 1 0.11 0 0.49 100.00
102 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21 100.00
103 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96 100.00
104 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91 100.00
105 INT89529 OPRM1 Regulation of CALM1 1 0.27 0 0.81 100.00
106 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46 100.00
107 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89 100.00
108 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1 100.00
109 INT76196 Binding of HTR1A and EIF2B3 1 0.06 0 0.17 100.00
110 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13 100.00
111 INT83220 Gucy1a2 Positive_regulation of Positive_regulation of Glp1r 1 0.02 0 0.26 100.00
112 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16 100.00
113 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95 100.00
114 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37 100.00
115 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22 100.00
116 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9 100.00
117 INT60047 Oprl1 Negative_regulation of Phosphorylation of Syn1 1 0.05 0.17 1.05 100.00
118 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73 100.00
119 INT167484 Binding of CHRNE and GGNBP2 1 0.02 0 0.5 100.00
120 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52 100.00
121 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88 100.00
122 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88 100.00
123 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88 100.00
124 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57 100.00
125 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57 100.00
126 INT266036 Gpr30 Positive_regulation of Positive_regulation of Mapk1 1 0.19 0.24 0.15 100.00
127 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32 100.00
128 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15 100.00
129 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47 100.00
130 INT223556 Churc1 Regulation of Cnr2 1 0.00 0.8 0.54 100.00
131 INT111840 Binding of Cnr1 and sar 1 0.04 0.45 0.52 100.00
132 INT110342 Binding of CNR1 and TRPV1 1 0.33 0 0.63 100.00
133 INT231026 Ppidl1 Positive_regulation of Gene_expression of Fos 1 0.01 0 0.4 100.00
134 INT79537 Hrh3 Regulation of Localization of Prl 1 0.13 0.4 0.18 100.00
135 INT140892 Penk Negative_regulation of Mnp 1 0.13 0.55 1.75 100.00
136 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51 100.00
137 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63 100.00
138 INT246683 exf Regulation of Gopc 1 0.01 0.2 0.14 100.00
139 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38 100.00
140 INT180447 Binding of Rhoa and Car2 1 0.17 0.56 0.13 100.00
141 INT269326 PRKCA Positive_regulation of Localization of TMPO 1 0.01 0 0.13 100.00
142 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18 100.00
143 INT293204 Binding of CNR2 and SLC25A37 1 0.01 0 0.36 100.00
144 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3 100.00
145 INT70836 Positive_regulation of OPRK1 Positive_regulation of Binding of CRYGS 1 0.03 0.09 0.36 100.00
146 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17 100.00
147 INT98572 Binding of ABAT and CRYGS 1 0.01 0 0.75 100.00
148 INT224125 Adrbk2 Positive_regulation of Phosphorylation of Adora3 1 0.04 0 0.13 100.00
149 INT224127 Grk5 Positive_regulation of Phosphorylation of Adora3 1 0.06 0 0.13 100.00
150 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 100.00
151 INT232293 Abat Regulation of Binding of Fig4 1 0.11 0 0.43 100.00
152 INT45335 Mlst8 Positive_regulation of Localization of Abat 1 0.36 0 0.65 100.00
153 INT45334 Mlst8 Regulation of Localization of Abat 1 0.21 0 0.65 100.00
154 INT269336 PRKCA Regulation of Localization of TMPO 1 0.01 0.12 0.13 100.00
155 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 100.00
156 INT295434 BRD2 Positive_regulation of Gene_expression of GNRH1 1 0.02 0.07 0.2 100.00
157 INT231032 Ppidl1 Positive_regulation of Gene_expression of Bst1 1 0.00 0 0.46 100.00
158 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56 100.00
159 INT52817 Oprd1 Regulation of Gnrh1 1 0.11 0.17 0.61 100.00
160 INT291545 Binding of Dlat and St8sia2 1 0.14 0.44 0.37 100.00
161 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18 100.00
162 INT337894 Ins1 Regulation of Gene_expression of Nr2f2 1 0.07 0.22 0.15 100.00
163 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54 100.00
164 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54 100.00
165 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28 100.00
166 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24 100.00
167 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13 100.00
168 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13 100.00
169 INT6415 Binding of Cpe and Oprd1 1 0.00 0 1.07 100.00
170 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79 100.00
171 INT86264 OPRK1 Negative_regulation of Gene_expression of HIVEP1 1 0.33 1.76 0.51 100.00
172 INT51025 Klra3 Positive_regulation of Gene_expression of Tac1 1 0.11 0 0.42 100.00
173 INT51026 Klra3 Positive_regulation of Gene_expression of Tacr3 1 0.05 0 0.42 100.00
174 INT264189 HR Positive_regulation of Gene_expression of IL10 1 0.00 1.48 0.19 100.00
175 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36 100.00
176 INT94033 Binding of Adarb1 and SLAMF6 1 0.01 0 1.61 100.00
177 INT91545 Binding of HTR1B and CALCRL 1 0.01 0.09 0.41 100.00
178 INT74852 Chrm1 Positive_regulation of Localization of Abat 1 0.11 0 0.66 100.00
179 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 100.00
180 INT168131 Phosphorylation of Yy1 Positive_regulation of Gene_expression of Mir190 1 0.32 0 0.45 100.00
181 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48 100.00
182 INT110407 Htr1a Positive_regulation of Gene_expression of Fos 1 0.50 0.52 0.66 100.00
183 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93 100.00
184 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93 100.00
185 INT13428 Gabrd Regulation of Localization of Sstr2 1 0.31 0 0.79 100.00
186 INT144153 Socs6 Positive_regulation of Gene_expression of Gabrg1 1 0.07 0 1.16 100.00
187 INT21534 Binding of Oprd1 and Il1 1 0.00 0 0.84 100.00
188 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77 100.00
189 INT118136 Binding of HTR1A and HTR2A 1 0.36 0.77 0.45 100.00
190 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58 100.00
191 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57 100.00
192 INT153924 Msr1 Regulation of Adrb3 1 0.02 0.24 0.32 100.00
193 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95 100.00
194 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44 100.00
195 INT147891 Prokr1 Positive_regulation of Localization of Abat 1 0.05 0.36 0.6 100.00
196 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52 100.00
197 INT76508 Pnoc Regulation of Oprl1 1 0.47 0.25 1.32 100.00
198 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47 100.00
199 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16 100.00
200 INT242203 GLP1R Regulation of GCG 1 0.04 0.64 0.1 100.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for agonist. They are ordered first by their pain relevance and then by number of times they were reported in agonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 100.00
2 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
3 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
4 INT3439 Localization of Abat 1017 0.78 112.39 727.06 100.00
5 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 100.00
6 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
7 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 100.00
8 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
9 INT477 Localization of Avp 813 0.81 131.58 300.4 100.00
10 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
11 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 100.00
12 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
13 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 100.00
14 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
15 INT103094 Binding of PPARA 308 0.47 177.26 34.75 100.00
16 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 100.00
17 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
18 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
19 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 100.00
20 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
21 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
22 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
23 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
24 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
25 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 100.00
26 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
27 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 100.00
28 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 100.00
29 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
30 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 100.00
31 INT3579 Localization of Oxt 555 0.81 43.35 292.44 100.00
32 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
33 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 100.00
34 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
35 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
36 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 100.00
37 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
38 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 100.00
39 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
40 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
41 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 100.00
42 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 100.00
43 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
44 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
45 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 100.00
46 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 100.00
47 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
48 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 100.00
49 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 100.00
50 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 100.00
51 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 100.00
52 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 100.00
53 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 100.00
54 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
55 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 100.00
56 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 100.00
57 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 100.00
58 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 100.00
59 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 100.00
60 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 100.00
61 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 100.00
62 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6 100.00
63 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 100.00
64 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 100.00
65 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
66 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 100.00
67 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
68 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22 100.00
69 INT63383 Binding of Cnr1 77 0.48 22.28 44.61 100.00
70 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 100.00
71 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 100.00
72 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 100.00
73 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57 100.00
74 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 100.00
75 INT4153 Binding of Insrr 109 0.40 17.99 72.15 100.00
76 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 100.00
77 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
78 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 100.00
79 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 100.00
80 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
81 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 100.00
82 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
83 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 100.00
84 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 100.00
85 INT173159 Localization of PPARA 96 0.74 64.55 10.26 100.00
86 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17 100.00
87 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 100.00
88 INT255981 Localization of RAB5A 3 0.68 0.88 4.76 100.00
89 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 100.00
90 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 100.00
91 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 100.00
92 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 100.00
93 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07 100.00
94 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 100.00
95 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38 100.00
96 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 100.00
97 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
98 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 100.00
99 INT6437 Binding of YY1 154 0.47 26.3 90.46 100.00
100 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
101 INT122037 Regulation of Ppara 93 0.62 56.28 12.89 100.00
102 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
103 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 100.00
104 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 100.00
105 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 100.00
106 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
107 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
108 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69 100.00
109 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
110 INT1438 Localization of Pomc 360 0.81 101.26 116.47 100.00
111 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 100.00
112 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 100.00
113 INT114 Binding of Oprl1 139 0.48 23 103.35 100.00
114 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 100.00
115 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
116 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
117 INT287 Localization of Cck 518 0.81 86.84 364.04 100.00
118 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45 100.00
119 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 100.00
120 INT7787 Positive_regulation of Akr1d1 52 0.66 3.55 31.71 100.00
121 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 100.00
122 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 100.00
123 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
124 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 100.00
125 INT6385 Regulation of Man2a2 48 0.61 7.8 24.68 100.00
126 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 100.00
127 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 100.00
128 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
129 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 100.00
130 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35 100.00
131 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 100.00
132 INT18400 Localization of Glp1r 97 0.80 11.96 24.32 100.00
133 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5 100.00
134 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23 100.00
135 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 100.00
136 INT7474 Gene_expression of Man2a2 38 0.67 3.31 18.42 100.00
137 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
138 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 100.00
139 INT6107 Localization of Npy 180 0.81 26.76 81.67 100.00
140 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 100.00
141 INT21186 Negative_regulation of Binding of Ptprg 28 0.44 1.78 27.04 100.00
142 INT6177 Binding of Htr1a 65 0.47 17.65 30.59 100.00
143 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 100.00
144 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 100.00
145 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 100.00
146 INT170922 Binding of Ppara 59 0.45 28.45 6.7 100.00
147 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 100.00
148 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 100.00
149 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
150 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 100.00
151 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
152 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 100.00
153 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09 100.00
154 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 100.00
155 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
156 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45 100.00
157 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 100.00
158 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 100.00
159 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
160 INT6849 Localization of IL1B 229 0.81 112.56 69.63 100.00
161 INT2212 Binding of Abat 89 0.48 18.36 63.99 100.00
162 INT50308 Binding of Cnr1 61 0.48 14.41 33.52 100.00
163 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 100.00
164 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 100.00
165 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 100.00
166 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 100.00
167 INT27529 Phosphorylation of Oprd1 23 0.47 1.16 20.18 100.00
168 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 100.00
169 INT9039 Negative_regulation of Htr1a 69 0.57 9.56 41.84 100.00
170 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31 100.00
171 INT8037 Negative_regulation of Man2a2 39 0.42 5.15 17.44 100.00
172 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 100.00
173 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 100.00
174 INT16194 Binding of CNR1 82 0.48 20.75 39.59 100.00
175 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75 100.00
176 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 100.00
177 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 100.00
178 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 100.00
179 INT7828 Positive_regulation of Oprd1 55 0.69 14.11 42.86 100.00
180 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 100.00
181 INT12608 Regulation of CNR1 62 0.60 24.36 36.02 100.00
182 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 100.00
183 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22 100.00
184 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 100.00
185 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
186 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
187 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 100.00
188 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04 100.00
189 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41 100.00
190 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31 100.00
191 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 100.00
192 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 100.00
193 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 100.00
194 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 100.00
195 INT8122 Regulation of Htr1a 39 0.60 8.96 24.89 100.00
196 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 100.00
197 INT451 Regulation of Oxt 142 0.62 22.07 69.42 100.00
198 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 100.00
199 INT29107 Regulation of Oprk1 31 0.45 6.16 26.61 100.00
200 INT35366 Binding of AR 87 0.47 30.52 8.9 100.00
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