P:analgesia

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pChart

Pain Term
Category Pain type
Synonyms None
Pain Specific Yes
Documents 31983
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for analgesia. They are ordered first by their pain relevance and then by number of times they were reported for analgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7 100.00
2 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45 100.00
3 INT61675 Binding of Gpm6a and Man2a2 1 0.00 0.08 1.67 100.00
4 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19 100.00
5 INT151382 St8sia1 Positive_regulation of Cck Regulation of St8sia1 1 0.04 0.22 1.35 100.00
6 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91 100.00
7 INT41617 Sp5 Positive_regulation of Mlf1 1 0.02 0.25 0.94 100.00
8 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61 100.00
9 INT149741 Rf Negative_regulation of Qrfp 1 0.00 0.26 1.06 100.00
10 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63 100.00
11 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12 99.96
12 INT158473 Binding of El1 and El2 1 0.20 0.42 0.86 99.92
13 INT143492 OPRL1 Regulation of PNOC 1 0.05 0 0.99 99.84
14 INT96462 Pnoc Positive_regulation of Pag1 1 0.01 0.74 2.45 99.72
15 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39 99.72
16 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34 99.72
17 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 99.68
18 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 99.68
19 INT112097 Sstr1 Positive_regulation of Adarb1 1 0.02 0.15 1.29 99.66
20 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68 99.66
21 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91 99.64
22 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97 99.60
23 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 99.58
24 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 99.58
25 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89 99.58
26 INT153215 Htr5b Positive_regulation of Pag1 1 0.01 0.57 1.22 99.48
27 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 99.48
28 INT54599 Positive_regulation of Ascla2 Positive_regulation of Nrm 1 0.00 0.14 0.52 99.48
29 INT61674 Gpm6a Regulation of Oprd1 1 0.01 0.07 1.62 99.44
30 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 99.40
31 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 99.40
32 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44 99.40
33 INT128512 Regulation of Pnoc Regulation of Adarb1 1 0.01 0.46 1.58 99.38
34 INT87891 Agt Regulation of Cck 1 0.28 0 1.97 99.32
35 INT45736 Prl Positive_regulation of Gene_expression of Gnrhr 1 0.00 0.1 0.56 99.24
36 INT166863 Kcnj9 Regulation of Kcnj6 1 0.20 0 0.56 99.24
37 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 99.20
38 INT128513 Pnoc Regulation of Adarb1 1 0.01 0.92 3.14 99.18
39 INT37873 Pag1 Regulation of Nrm 2 0.04 1.1 2.41 99.16
40 INT57956 LOC365260 Negative_regulation of Cck 1 0.11 0 1.3 99.16
41 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2 99.08
42 INT69177 UBA7 Negative_regulation of Igk 1 0.00 0.15 0.54 99.08
43 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6 99.04
44 INT32326 Regulation of DBI Positive_regulation of GH1 1 0.02 0 0.21 99.04
45 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43 98.92
46 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54 98.86
47 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67 98.72
48 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27 98.68
49 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05 98.64
50 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05 98.64
51 INT12052 Xcl1 Negative_regulation of Rnpep 1 0.01 0 0.71 98.56
52 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58 98.44
53 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02 98.20
54 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02 98.20
55 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02 98.20
56 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21 98.12
57 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04 98.12
58 INT32325 DBI Positive_regulation of GHRH 1 0.02 0 0.21 97.88
59 INT32328 DBI Positive_regulation of GH1 1 0.03 0 0.21 97.88
60 INT32331 DBI Positive_regulation of Localization of GHRH 1 0.02 0 0.21 97.88
61 INT77330 Oprk1 Regulation of Localization of GRIN1 1 0.24 0 0.91 97.68
62 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65 97.68
63 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38 97.52
64 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03 97.44
65 INT88556 Lpo Negative_regulation of AOS 1 0.11 0 0.66 97.28
66 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88 97.20
67 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86 97.20
68 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41 96.80
69 INT29366 Mnt Positive_regulation of Localization of Penk 1 0.01 0 0.96 96.76
70 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93 96.64
71 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98 96.52
72 INT137308 sps Negative_regulation of Cstb 1 0.03 1.59 0.31 96.44
73 INT161412 Pag1 Positive_regulation of Gene_expression of Tens1 1 0.11 0.56 0.9 96.44
74 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 96.32
75 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41 96.20
76 INT14095 Binding of Vsig2 and Coq10a 2 0.33 1.98 4.55 96.12
77 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63 95.98
78 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52 95.96
79 INT51568 Acyp2-ps1 Positive_regulation of Positive_regulation of Fos 1 0.35 0.19 0.56 95.68
80 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91 95.64
81 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62 95.60
82 INT13756 Binding of Oprd1 and Scn4a 1 0.02 0 1.32 95.56
83 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95 95.56
84 INT253826 Cck Regulation of Nts 1 0.21 0.36 0.94 95.56
85 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32 95.46
86 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53 95.36
87 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51 95.36
88 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46 95.36
89 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36 95.36
90 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36 95.36
91 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07 95.20
92 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63 95.08
93 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79 95.08
94 INT81661 Binding of Nfkb1 and Pdyn 1 0.00 0 0.5 95.04
95 INT102316 Ugt1a6a Positive_regulation of Cyb5 1 0.16 0.08 0.64 94.88
96 INT110407 Htr1a Positive_regulation of Gene_expression of Fos 1 0.50 0.52 0.66 94.68
97 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07 94.60
98 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07 94.60
99 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 94.48
100 INT123987 RGS17 Positive_regulation of Rgs20 1 0.13 0 1.09 94.28
101 INT156971 Kcnip3 Negative_regulation of Creb1 1 0.48 0.46 0.17 94.20
102 INT153897 Binding of KCNJ3 and Snx27 1 0.03 0.28 0.5 94.16
103 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 94.16
104 INT122426 Binding of Hint1 and Ighm 1 0.00 0 0.5 93.88
105 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 93.68
106 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1 93.68
107 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1 93.68
108 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 93.68
109 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1 93.68
110 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1 93.68
111 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1 93.68
112 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06 93.60
113 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 1 0.13 0 0.54 93.52
114 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54 93.52
115 INT145577 Regulation of Binding of Adra2c and Hcn2 1 0.25 0.19 0.4 93.30
116 INT145574 Regulation of Binding of Adra2c and Hcn4 1 0.26 0.19 0.4 93.30
117 INT149632 Binding of HK1 and NCOR2 1 0.01 0.13 1.58 93.20
118 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71 93.20
119 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72 93.08
120 INT145576 Binding of Adra2c and Hcn4 1 0.21 0.19 0.4 93.06
121 INT145575 Binding of Adra2c and Hcn2 1 0.21 0.19 0.4 93.06
122 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66 92.96
123 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14 92.92
124 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81 92.76
125 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3 92.72
126 INT94366 Binding of ARRB1 and OPRD1 1 0.11 0 0.67 92.72
127 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 92.68
128 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 92.64
129 INT153896 Snx27 Regulation of KCNJ3 1 0.04 0.17 0.33 92.60
130 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29 92.52
131 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31 92.36
132 INT56205 Binding of Ap1m2 and Insrr 1 0.00 0.07 0.96 92.36
133 INT32327 POMC Positive_regulation of Localization of PRL 4 0.45 0 0.99 92.32
134 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01 92.12
135 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31 91.96
136 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33 91.92
137 INT106838 Lyar Regulation of Oprm1 1 0.04 0.28 0.8 91.92
138 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88 91.88
139 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29 91.80
140 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7 91.76
141 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 91.68
142 INT32330 POMC Positive_regulation of Localization of GHRH 1 0.12 0 0.24 91.48
143 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78 91.40
144 INT76237 Olr594 Positive_regulation of Gene_expression of Fos 1 0.05 0.09 0.59 91.32
145 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9 91.16
146 INT115049 Crem Regulation of Gene_expression of Pdyn 1 0.20 0.32 0.96 91.12
147 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81 90.88
148 INT6320 Binding of Rbm39 and Scq1 1 0.03 0 1.92 90.56
149 INT69178 Binding of SLC3A2 and Adarb1 1 0.00 0.16 0.53 90.56
150 INT69179 Binding of UBA7 and Adarb1 1 0.00 0.16 0.53 90.56
151 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05 90.48
152 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57 90.48
153 INT105771 CRH Negative_regulation of Localization of GNRH1 1 0.35 0.56 0.39 90.24
154 INT156970 Negative_regulation of Kcnip3 Positive_regulation of Transcription of Creb1 1 0.47 0.45 0.17 90.04
155 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94 89.92
156 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93 89.92
157 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93 89.92
158 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57 89.80
159 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 89.80
160 INT63519 Hrh1 Regulation of H2 1 0.02 0.36 0.39 89.60
161 INT45663 Fpr1 Positive_regulation of Penk 1 0.15 0 0.63 89.44
162 INT211744 Binding of Gopc and Mors1 1 0.10 0.2 1.48 89.08
163 INT81662 Pdyn Positive_regulation of Nfkb1 1 0.00 0 0.48 89.04
164 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93 89.04
165 INT144795 Binding of Cnr1 and Gm4113 1 0.00 0.22 0.38 88.96
166 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28 88.80
167 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95 88.76
168 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94 88.76
169 INT47956 Cck Positive_regulation of Gast 1 0.02 0.09 1.25 88.72
170 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67 88.52
171 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11 88.48
172 INT33314 Binding of Ap1m1 and Ap1m2 1 0.07 0.97 5.42 88.36
173 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61 88.16
174 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53 88.08
175 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58 88.00
176 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93 87.76
177 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 0.00 0.11 1.93 87.76
178 INT56132 CALCA Positive_regulation of Localization of POMC 1 0.51 0.16 0.44 87.52
179 INT118545 Binding of Agtr2 and Msr1 1 0.00 0.09 0.29 87.36
180 INT154111 POMC Positive_regulation of Localization of PENK 1 0.34 0.05 1.41 86.96
181 INT154110 PENK Positive_regulation of Localization of POMC 1 0.34 0.05 1.41 86.96
182 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38 86.92
183 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38 86.92
184 INT26997 SST Positive_regulation of Negative_regulation of Gnrhr 1 0.00 0.08 0.59 86.80
185 INT186150 Camk4 Regulation of Gene_expression of Oxt 1 0.20 1.24 0.2 86.64
186 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57 86.64
187 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49 86.56
188 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41 86.52
189 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 86.48
190 INT31243 Binding of Mme and Cpe 1 0.01 0 0.72 86.40
191 INT34837 Maob Regulation of Negative_regulation of Mme 1 0.48 0.15 0.92 86.08
192 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41 85.88
193 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98 85.88
194 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65 85.48
195 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24 85.24
196 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23 85.24
197 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5 85.04
198 INT75992 Binding of Pvalb and Lgals3 1 0.00 0 0.56 84.96
199 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3 84.92
200 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06 84.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for analgesia. They are ordered first by their pain relevance and then by number of times they were reported in analgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
2 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
4 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
5 INT6971 Regulation of St8sia1 9 0.44 3.25 10.04 100.00
6 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
7 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
8 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 100.00
9 INT6969 Negative_regulation of St8sia1 12 0.42 6.36 12.96 100.00
10 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
11 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
12 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
13 INT158 Localization of Prl 2431 0.81 378.96 952.2 100.00
14 INT6970 Gene_expression of St8sia1 13 0.52 4.94 9.27 100.00
15 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
16 INT79149 Gene_expression of CSE 26 0.58 11.76 14.16 100.00
17 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
18 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37 100.00
19 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
20 INT39967 Positive_regulation of VSPA 3 0.69 1.04 4.31 100.00
21 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
22 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
23 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 100.00
24 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
25 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
26 INT84769 Positive_regulation of St8sia1 10 0.41 7.56 9.86 100.00
27 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48 100.00
28 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 100.00
29 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 100.00
30 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 100.00
31 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 100.00
32 INT6968 Positive_regulation of Gene_expression of St8sia1 1 0.06 0.26 3.36 100.00
33 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
34 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 100.00
35 INT1703 Regulation of PCa 52 0.52 23.65 20.6 100.00
36 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
37 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
38 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 100.00
39 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
40 INT45440 Negative_regulation of VSPA 1 0.37 0.47 3.07 100.00
41 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
42 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4 100.00
43 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
44 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05 100.00
45 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 100.00
46 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 100.00
47 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
48 INT60142 Negative_regulation of Serpinb1a 2 0.42 0.59 2.46 100.00
49 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
50 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 100.00
51 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 100.00
52 INT87794 Positive_regulation of Mors1 19 0.38 4.74 20.23 100.00
53 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 100.00
54 INT109940 Negative_regulation of Siafq1 1 0.10 1.22 1.43 100.00
55 INT1706 Negative_regulation of PCa 33 0.47 10.7 15.27 100.00
56 INT3117 Regulation of Oxt 103 0.61 17.93 32.28 100.00
57 INT45179 Gene_expression of sea 8 0.58 3.4 2.99 100.00
58 INT77804 Regulation of Ednra 9 0.39 2.71 7.94 100.00
59 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
60 INT32072 Positive_regulation of sea 7 0.40 0.91 1.44 100.00
61 INT71760 Binding of CSE 9 0.48 2.84 5.42 100.00
62 INT30925 Gene_expression of Mif-ps1 6 0.73 1.63 4.74 100.00
63 INT1463 Binding of Pomc 129 0.48 15.89 56.27 100.00
64 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 100.00
65 INT38375 Gene_expression of Siafq1 4 0.51 1.5 3.98 100.00
66 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77 100.00
67 INT37668 Positive_regulation of TEAD2 3 0.28 0 1.5 100.00
68 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81 100.00
69 INT10869 Regulation of Npff 3 0.45 0.37 3.15 100.00
70 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83 100.00
71 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 100.00
72 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 100.00
73 INT5137 Binding of PCa 45 0.47 16.91 18.47 100.00
74 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47 100.00
75 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 100.00
76 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 100.00
77 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2 100.00
78 INT4430 Regulation of Eda 2 0.23 0.38 1.24 100.00
79 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
80 INT2947 Regulation of TFPI 10 0.44 5.81 4.86 100.00
81 INT79148 Regulation of CSE 1 0.14 0.19 1.74 100.00
82 INT58602 Gene_expression of HMI 34 0.65 25.26 3.74 100.00
83 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06 100.00
84 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
85 INT13351 Regulation of Gene_expression of St8sia1 1 0.12 0.74 1.5 100.00
86 INT73351 Negative_regulation of Pnoc 13 0.42 5.71 14.17 100.00
87 INT5598 Negative_regulation of Pdyn 95 0.59 14.4 55.43 100.00
88 INT13243 Gene_expression of Sqstm1 4 0.30 2.07 2.06 100.00
89 INT6239 Regulation of Regulation of Oprd1 7 0.45 0.34 7.26 100.00
90 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3 100.00
91 INT281144 Regulation of Gene_expression of Ccr2 2 0.44 2.38 3.29 100.00
92 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 100.00
93 INT72822 Negative_regulation of Gene_expression of Oxt 6 0.41 2.48 1.12 100.00
94 INT22877 Gene_expression of Nidd3k 1 0.46 0 4.34 100.00
95 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51 100.00
96 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 100.00
97 INT60863 Regulation of Gpm6a 6 0.36 1.62 4.48 100.00
98 INT61673 Regulation of LOC100360318 2 0.07 0.16 2.73 100.00
99 INT2066 Localization of Agt 56 0.80 9.95 16.25 100.00
100 INT50070 Negative_regulation of NFKBIL1 14 0.48 3.76 5.92 100.00
101 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 100.00
102 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37 100.00
103 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
104 INT32217 Positive_regulation of Cntn3 1 0.05 0.14 1.06 100.00
105 INT162193 Regulation of Regulation of PCA 1 0.23 0 0.82 100.00
106 INT26525 Positive_regulation of Siafq1 1 0.01 0 1.49 100.00
107 INT39968 Negative_regulation of Positive_regulation of VSPA 1 0.43 0.25 0.66 100.00
108 INT5996 Positive_regulation of NFKBIL1 4 0.12 1.24 4.1 100.00
109 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
110 INT128906 Gene_expression of Kcnj5 35 0.43 7.48 10.33 100.00
111 INT70420 Positive_regulation of Localization of ACOT1 11 0.30 1.26 2.25 100.00
112 INT39116 Regulation of Gene_expression of Ptger2 29 0.51 10.25 6.46 100.00
113 INT74286 Regulation of Il10 42 0.44 28.06 19.44 100.00
114 INT37667 Negative_regulation of Positive_regulation of TEAD2 1 0.15 0 0.69 100.00
115 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
116 INT42320 Positive_regulation of Regulation of Trh 1 0.50 0.15 0.74 100.00
117 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29 100.00
118 INT1149 Binding of ecs 19 0.37 13.67 3.9 100.00
119 INT118374 Negative_regulation of Npff 2 0.42 0.59 2.56 100.00
120 INT32909 Negative_regulation of A1cf 2 0.43 0.64 1.16 100.00
121 INT12734 Regulation of Binding of Oprl1 10 0.62 2.23 7.71 100.00
122 INT74394 Negative_regulation of Gad2 6 0.42 1.96 5.26 100.00
123 INT142042 Localization of Sec16a 1 0.10 1.04 1.27 100.00
124 INT19805 Negative_regulation of Avp 18 0.59 4.57 5.87 100.00
125 INT42319 Gene_expression of Hpd 5 0.44 11.25 0.9 100.00
126 INT42321 Regulation of Gene_expression of Hpd 1 0.20 0.1 0.54 100.00
127 INT2153 Negative_regulation of Positive_regulation of Oxt 9 0.42 1.14 1.52 100.00
128 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22 100.00
129 INT53520 Binding of Igh-Dex 4 0.28 0.47 3.25 100.00
130 INT29598 Binding of Cyp21a1 5 0.31 0.09 1.71 100.00
131 INT7030 Regulation of Gene_expression of Pdyn 23 0.61 5.77 14.18 100.00
132 INT921 Regulation of GH1 172 0.60 52.88 51.04 100.00
133 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 100.00
134 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24 100.00
135 INT198840 Transcription of EDA 1 0.58 0.97 1.26 100.00
136 INT86898 Negative_regulation of Gene_expression of Cnr1 13 0.55 3.33 7.25 100.00
137 INT92151 Regulation of Faah 5 0.62 6.31 3.06 100.00
138 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47 100.00
139 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21 100.00
140 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06 100.00
141 INT16205 Localization of ras 25 0.73 18.99 1.85 100.00
142 INT83581 Positive_regulation of Localization of ras 5 0.49 3.07 0.56 100.00
143 INT83582 Negative_regulation of Localization of ras 2 0.12 2.23 0.48 100.00
144 INT96969 Positive_regulation of Positive_regulation of CNR1 9 0.48 1.27 7.19 100.00
145 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
146 INT20408 Regulation of Negative_regulation of Pomc 3 0.45 0.38 3.51 100.00
147 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3 100.00
148 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 100.00
149 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11 100.00
150 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 100.00
151 INT54295 Negative_regulation of Localization of Spnb4 2 0.57 0 2.21 100.00
152 INT861 Negative_regulation of Ptger1 9 0.37 3.84 3.48 100.00
153 INT109378 Regulation of Phosphorylation of Fos 3 0.26 1.61 2.45 100.00
154 INT24420 Transcription of Pomc 13 0.69 3.32 4.54 100.00
155 INT131007 Positive_regulation of Transcription of Pomc 2 0.49 1.68 0.86 100.00
156 INT131005 Transcription of Mc2r 1 0.45 0.78 0.76 100.00
157 INT131006 Positive_regulation of Transcription of Mc2r 1 0.33 0.78 0.76 100.00
158 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83 100.00
159 INT12575 Regulation of Hpse 33 0.59 17.7 18.45 100.00
160 INT64192 Regulation of Gtf2a2 3 0.19 0.87 6.36 100.00
161 INT135087 Negative_regulation of Gene_expression of Phax 5 0.17 4.39 4.1 100.00
162 INT38681 Regulation of Positive_regulation of FAM49B 1 0.44 0 0.38 100.00
163 INT15307 Regulation of Mtor 27 0.48 4.7 9.34 100.00
164 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08 100.00
165 INT5402 Regulation of Bdh2 3 0.01 1.04 0.86 100.00
166 INT41703 Regulation of HBD 1 0.03 0.32 0.44 100.00
167 INT11275 Regulation of Fos 37 0.60 5.79 18.18 100.00
168 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 100.00
169 INT59493 Regulation of Transcription of HYAL1 1 0.00 0 0.5 100.00
170 INT4028 Regulation of HYAL1 8 0.54 1.55 1.8 100.00
171 INT28857 Negative_regulation of Positive_regulation of Pag1 11 0.30 8.46 10.19 100.00
172 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 100.00
173 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
174 INT160 Regulation of Positive_regulation of Prl 37 0.62 7.56 20.09 100.00
175 INT59 Regulation of Adrb1 25 0.42 8.32 9.78 100.00
176 INT51269 Gene_expression of HIST2H2AA3 16 0.56 10.16 6.55 100.00
177 INT26459 Regulation of Prl 14 0.62 7.27 4.92 100.00
178 INT6928 Regulation of Tfpi 4 0.26 1.06 2.61 100.00
179 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99 100.00
180 INT43165 Regulation of Positive_regulation of Gnrhr 3 0.27 0.1 1.86 100.00
181 INT51127 Regulation of Nsa2 2 0.23 0.51 1.84 100.00
182 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64 100.00
183 INT130891 Regulation of Gene_expression of Mdk 2 0.38 1.38 0.65 100.00
184 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 99.98
185 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.98
186 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.98
187 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 99.98
188 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 99.98
189 INT790 Gene_expression of Mastl 22 0.68 4.56 10.23 99.98
190 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.98
191 INT95323 Gene_expression of D2Mit212 3 0.18 1.16 7.12 99.98
192 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 99.98
193 INT66779 Binding of Pnoc 79 0.48 6.43 60.46 99.98
194 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 99.98
195 INT70729 Gene_expression of Zswim2 1 0.42 0.24 0.48 99.98
196 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 99.98
197 INT5596 Negative_regulation of Gene_expression of Pdyn 41 0.59 5.34 24.36 99.98
198 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 99.98
199 INT27691 Binding of PRSS3P2 1 0.33 0 0.36 99.98
200 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 99.98
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