P:antiallodynic

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pChart

Pain Term
Category Drug class
Synonyms Anti Allodynic
Pain Specific No
Documents 252
Hot Single Events 175
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for antiallodynic. They are ordered first by their pain relevance and then by number of times they were reported for antiallodynic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 98.72
2 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39 90.08
3 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31 83.20
4 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95 75.00
5 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93 75.00
6 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93 75.00
7 INT138015 Binding of Paf and Positive_regulation of Mpo 1 0.23 0.53 0.33 75.00
8 INT138014 Gm2170 Negative_regulation of Positive_regulation of Mpo 1 0.01 0.53 0.32 75.00
9 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 75.00
10 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47 75.00
11 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47 75.00
12 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37 75.00
13 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53 75.00
14 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 75.00
15 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69 75.00
16 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68 75.00
17 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68 75.00
18 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54 43.52
19 INT311255 Binding of Gpi1 and Nt5e 1 0.05 0.16 0.13 39.44
20 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28 38.36
21 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28 38.36
22 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36 5.00
23 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86 5.00
24 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85 5.00
25 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71 5.00
26 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64 5.00
27 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51 5.00
28 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for antiallodynic. They are ordered first by their pain relevance and then by number of times they were reported in antiallodynic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT137665 Regulation of Gsta3 1 0.28 0.17 0.34 100.00
2 INT192967 Gene_expression of Hp 14 0.43 8.06 11.01 99.98
3 INT192964 Positive_regulation of Hp 7 0.28 2 2.75 99.98
4 INT273122 Positive_regulation of Positive_regulation of Hp 1 0.26 0.08 0.58 99.98
5 INT273126 Positive_regulation of Binding of Hp 1 0.26 0.08 0.58 99.98
6 INT9167 Binding of Adora1 6 0.40 0.53 6.9 99.98
7 INT103219 Regulation of Pde12 2 0.26 1.2 1.22 99.98
8 INT1864 Regulation of Bche 18 0.47 6.18 2.44 99.98
9 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08 99.96
10 INT124683 Gene_expression of Pia8 3 0.41 2.17 7.11 99.84
11 INT7044 Positive_regulation of Positive_regulation of Htr1a 17 0.67 3.5 10 99.84
12 INT244294 Regulation of Gene_expression of Pia8 1 0.24 0.53 0.7 99.84
13 INT273123 Binding of Hp 1 0.25 3.56 10.9 99.76
14 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.74
15 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 99.74
16 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 99.62
17 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.52
18 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62 99.48
19 INT88008 Positive_regulation of Gene_expression of GDNF 14 0.70 8.9 3.61 99.48
20 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.46
21 INT101699 Regulation of Adora1 14 0.61 3.7 7.59 99.44
22 INT8233 Positive_regulation of Gene_expression of Paf 5 0.49 3.76 2.24 99.44
23 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38 99.40
24 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31 99.32
25 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 99.24
26 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13 99.24
27 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84 99.16
28 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58 99.00
29 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 98.98
30 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 98.96
31 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 98.96
32 INT142530 Negative_regulation of Positive_regulation of Mt2A 1 0.43 0.36 1.23 98.92
33 INT142531 Positive_regulation of Mt2A 1 0.70 0.36 1.22 98.92
34 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 98.88
35 INT8122 Regulation of Htr1a 39 0.60 8.96 24.89 98.84
36 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 98.78
37 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 98.74
38 INT93463 Localization of Hcrt 13 0.78 1.58 3.51 98.72
39 INT113635 Positive_regulation of Localization of Hcrt 1 0.49 0.51 1.06 98.72
40 INT8232 Gene_expression of Paf 21 0.67 22.18 12.8 98.62
41 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65 98.52
42 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 98.40
43 INT32452 Binding of Ptafr 5 0.42 2.6 0.58 98.40
44 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86 98.36
45 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 98.30
46 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 98.28
47 INT106687 Positive_regulation of Cacna2d1 1 0.39 0.82 1.1 98.08
48 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 98.04
49 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 97.94
50 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 97.92
51 INT258165 Localization of Ino80b 1 0.03 0 0.37 97.92
52 INT165644 Regulation of Transcription of Pde5a 1 0.44 1.65 0.91 97.80
53 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 97.76
54 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 97.72
55 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 97.60
56 INT136675 Transcription of Pde5a 6 0.63 4.74 2.71 97.58
57 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 97.52
58 INT258168 Gene_expression of Ino80b 2 0.03 0.05 0.37 97.52
59 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 97.44
60 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 97.44
61 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 97.36
62 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 97.30
63 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 97.28
64 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85 97.22
65 INT78850 Localization of Asap1 15 0.68 5.83 5.28 97.20
66 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 97.08
67 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 97.04
68 INT110269 Binding of Gabbr1 2 0.36 2.1 2.18 96.96
69 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 96.96
70 INT240986 Regulation of Agtrap 4 0.45 2.21 0.88 96.96
71 INT292 Localization of Penk 876 0.81 88.44 669.14 96.92
72 INT51318 Binding of Pia8 2 0.26 1.38 5.39 96.80
73 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 96.72
74 INT113636 Positive_regulation of Hcrtr1 10 0.70 8.29 5.18 96.72
75 INT192970 Negative_regulation of Hp 7 0.22 6.99 4.06 96.60
76 INT98942 Gene_expression of Dtd1 1 0.52 0.36 0.3 96.56
77 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25 96.48
78 INT254145 Gene_expression of Ppap2a 9 0.10 2.66 4.33 96.44
79 INT244295 Positive_regulation of Pia8 1 0.37 0.47 1.02 96.44
80 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 96.28
81 INT21951 Negative_regulation of Gene_expression of GDNF 5 0.43 2.82 1.57 96.28
82 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 96.20
83 INT30377 Negative_regulation of Pia8 2 0.37 0.52 1.79 96.16
84 INT126500 Regulation of Gene_expression of GRIN1 2 0.44 0.12 2.01 96.16
85 INT10694 Binding of Bche 19 0.48 8.03 4.85 95.84
86 INT273125 Positive_regulation of Localization of Hp 1 0.26 0.45 0.78 95.76
87 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65 95.76
88 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98 95.76
89 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 95.36
90 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 95.32
91 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 95.24
92 INT35284 Positive_regulation of Chrm1 14 0.67 5.64 10.11 94.80
93 INT123306 Negative_regulation of Positive_regulation of Chrm1 3 0.32 0.72 2.63 94.80
94 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 94.76
95 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 94.76
96 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 94.76
97 INT148863 Positive_regulation of Localization of GAD1 1 0.38 1.41 1 94.76
98 INT273128 Protein_catabolism of Hp 3 0.47 2.2 1.39 94.48
99 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 94.40
100 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 94.40
101 INT149079 Binding of Pid1 2 0.33 1.3 1.58 94.20
102 INT119785 Localization of GAD1 7 0.63 5.99 4.34 93.84
103 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38 93.76
104 INT273127 Localization of Hp 1 0.39 0.45 0.77 93.60
105 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 93.60
106 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63 93.44
107 INT105294 Positive_regulation of Ctps2 1 0.08 0.74 0.84 93.44
108 INT99567 Positive_regulation of MC2R 1 0.01 0.72 1.13 93.40
109 INT19488 Localization of ABAT 56 0.69 21.51 50.56 93.20
110 INT148864 Localization of DRGX 11 0.17 7.67 8.36 93.00
111 INT85789 Gene_expression of Prlh 10 0.78 4.5 5.47 92.72
112 INT85787 Transcription of Prlh 4 0.53 1.77 2.7 92.72
113 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24 92.72
114 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71 92.72
115 INT81597 Transcription of Npff 10 0.69 5.52 8.53 92.36
116 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37 92.36
117 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 92.24
118 INT32910 Positive_regulation of Gene_expression of Oprl1 22 0.70 7.07 19.03 92.00
119 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 91.52
120 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13 91.52
121 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25 91.40
122 INT59662 Localization of Ugt1a6 4 0.71 0.44 3.52 91.40
123 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26 91.24
124 INT86790 Gene_expression of P2rx6 34 0.74 14.04 15.92 91.20
125 INT113633 Gene_expression of Nqo2 1 0.05 0.41 0.77 91.20
126 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 91.16
127 INT54177 Positive_regulation of Epha2 2 0.11 0.42 2.12 91.12
128 INT244293 Localization of Epha2 1 0.09 0.44 1.54 91.12
129 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 90.88
130 INT258162 Positive_regulation of Gene_expression of Ppap2a 3 0.09 1.4 1.88 90.52
131 INT13683 Regulation of Ugt1a6 9 0.28 2.5 6.33 90.52
132 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 90.32
133 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 90.28
134 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 90.08
135 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 89.84
136 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 89.84
137 INT135449 Transcription of Kcnj11 1 0.06 0.64 0.53 89.76
138 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 89.76
139 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 89.76
140 INT1487 Regulation of Cpe 68 0.62 10.24 52.91 89.52
141 INT135447 Transcription of Abcc8 5 0.63 1.55 1.64 89.44
142 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 89.32
143 INT14054 Positive_regulation of H2-Ab1 10 0.69 2.98 6.25 89.32
144 INT113634 Gene_expression of Hcrtr1 5 0.77 34.43 3.76 89.28
145 INT135448 Transcription of Abcc9 3 0.12 1.45 1.35 89.20
146 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84 89.04
147 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 88.64
148 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 88.64
149 INT81153 Gene_expression of Hcrt 31 0.77 6.04 8.16 88.56
150 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 88.56
151 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07 88.56
152 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25 88.24
153 INT71406 Regulation of Dll1 3 0.35 0.79 4.44 88.24
154 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73 88.24
155 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 87.92
156 INT177684 Binding of Ppap2a 5 0.05 0.16 0.43 87.76
157 INT53500 Negative_regulation of Ppap2a 11 0.45 3.31 1.92 87.52
158 INT258161 Negative_regulation of Negative_regulation of Ppap2a 1 0.05 0.35 0.75 87.52
159 INT127681 Binding of Ugt1a6 7 0.47 0.79 4 87.28
160 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 86.16
161 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78 84.56
162 INT241733 Negative_regulation of Nt5e 4 0.40 2.84 1.58 83.92
163 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 83.92
164 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 82.88
165 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 82.72
166 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 82.72
167 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 82.48
168 INT215575 Gene_expression of P2ry6 10 0.64 3.43 3.72 82.40
169 INT55792 Regulation of Negative_regulation of Bche 11 0.57 1.78 3.21 82.08
170 INT165648 Negative_regulation of Transcription of Pde5a 1 0.41 3.6 1.93 81.68
171 INT192968 Positive_regulation of Gene_expression of Hp 2 0.28 1.34 1.44 81.60
172 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 81.36
173 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08 81.24
174 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 81.04
175 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14 80.52
176 INT249754 Phosphorylation of Adp 2 0.10 1.2 2.1 79.68
177 INT21185 Binding of Ptprg 213 0.47 13.49 157.75 79.44
178 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76 79.04
179 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6 78.24
180 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 77.84
181 INT38189 Regulation of Svs4 6 0.24 2.68 3.35 77.68
182 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86 77.68
183 INT215595 Regulation of P2ry6 1 0.22 1.4 1.12 77.68
184 INT216650 Regulation of P2ry4 1 0.14 0.69 0.62 77.68
185 INT273124 Positive_regulation of Negative_regulation of Hp 1 0.26 0.54 0.91 77.60
186 INT85786 Localization of Prlh 3 0.75 0.87 1.57 77.44
187 INT33134 Negative_regulation of Aadac 5 0.37 0.46 2.43 77.32
188 INT258166 Phosphorylation of Ppap2a 1 0.10 0.97 2.1 77.04
189 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 76.56
190 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75 76.20
191 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 76.20
192 INT21435 Positive_regulation of Negative_regulation of Adarb1 7 0.39 3.13 6.5 76.08
193 INT162102 Gene_expression of Gch1 3 0.72 23.65 27.96 76.08
194 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 76.08
195 INT113638 Negative_regulation of Hcrt 5 0.57 0.9 2.63 75.68
196 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 75.60
197 INT94199 Regulation of DRGX 9 0.07 8.31 10.39 75.28
198 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17 75.20
199 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 75.12
200 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 75.12
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