P:antidepressant

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pChart

Pain Term
Category Drug class
Synonyms Antidepressants
Pain Specific No
Documents 6332
Hot Single Events 200
Hot Interactions 166

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for antidepressant. They are ordered first by their pain relevance and then by number of times they were reported for antidepressant. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57 100.00
2 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 100.00
3 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 100.00
4 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46 100.00
5 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45 100.00
6 INT305731 Binding of Bdnf and Creb1 Positive_regulation of BDNF 1 0.11 0.49 0.47 100.00
7 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47 100.00
8 INT305747 Binding of Bdnf and Creb1 Positive_regulation of Bdnf 1 0.03 0.49 0.47 100.00
9 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47 100.00
10 INT305745 Binding of Bdnf and Positive_regulation of BDNF 1 0.17 0.44 0.44 100.00
11 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63 100.00
12 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67 100.00
13 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67 100.00
14 INT137099 Dlst Regulation of Sec22b 1 0.05 0 0.64 100.00
15 INT137100 Dlst Regulation of Htr1a 1 0.18 0 0.64 100.00
16 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05 100.00
17 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05 100.00
18 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49 100.00
19 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35 100.00
20 INT273020 Binding of FGF9 and PDE11A 1 0.22 0.3 0.11 100.00
21 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11 100.00
22 INT273017 Binding of PDE1B and PDE11A 1 0.08 0.35 0.14 100.00
23 INT273019 Binding of PDE1A and MDD1 1 0.30 0.69 0.12 99.84
24 INT47694 sps Regulation of Ntrk2 1 0.00 0.98 0.2 99.80
25 INT47695 sps Regulation of Bdnf 1 0.00 0.98 0.2 99.80
26 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65 99.78
27 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67 99.76
28 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66 99.76
29 INT327562 Binding of MCS and AKR1B10 1 0.00 0.5 0.41 99.76
30 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47 99.68
31 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 99.66
32 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67 99.62
33 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65 99.58
34 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34 99.54
35 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14 99.46
36 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46 99.44
37 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25 99.40
38 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 99.36
39 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31 99.36
40 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53 99.24
41 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6 99.20
42 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6 99.20
43 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57 99.16
44 INT266811 Binding of HRH1 and HTR2C 1 0.23 2.06 1.4 99.06
45 INT94665 Nisch Negative_regulation of Maoa 1 0.07 0 0.83 99.04
46 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57 99.00
47 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5 98.98
48 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4 98.96
49 INT167982 Mapk14 Negative_regulation of gr 1 0.02 0.45 0.29 98.96
50 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66 98.86
51 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84 98.84
52 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84 98.84
53 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84 98.84
54 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66 98.74
55 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1 98.40
56 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74 98.40
57 INT137103 Sec22b Regulation of Htr1a 1 0.09 0 1.02 98.32
58 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 97.96
59 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 97.96
60 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89 97.80
61 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52 97.72
62 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52 97.72
63 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95 97.66
64 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31 97.56
65 INT304458 Binding of P2rx4 and P2rx6 1 0.14 0 0.17 97.56
66 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 97.52
67 INT343599 Gys1 Regulation of Tst 1 0.01 0 0.75 97.48
68 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43 97.48
69 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 97.40
70 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56 97.36
71 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57 96.96
72 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57 96.96
73 INT290857 PPR Regulation of Fig4 1 0.02 0.45 0.21 96.88
74 INT290855 PPR Regulation of Ca2 1 0.01 0.45 0.2 96.88
75 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52 96.72
76 INT153924 Msr1 Regulation of Adrb3 1 0.02 0.24 0.32 96.32
77 INT70422 Binding of Htr1a and Adarb1 1 0.01 0.37 0.81 96.28
78 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4 96.24
79 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56 96.00
80 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07 95.74
81 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 95.72
82 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5 95.68
83 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09 95.68
84 INT63519 Hrh1 Regulation of H2 1 0.02 0.36 0.39 95.48
85 INT315333 Binding of Cflar and Fadd 1 0.01 0.49 0.42 95.32
86 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49 95.24
87 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 95.24
88 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46 94.96
89 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 94.96
90 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62 94.00
91 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 94.00
92 INT57674 ecs Regulation of htr 1 0.01 0.15 0.35 93.76
93 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95 93.44
94 INT335565 Binding of KDM5D and SPNS1 1 0.02 0 0.13 93.44
95 INT305739 Binding of nt and Trpv1 1 0.00 0.24 0.29 93.40
96 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43 93.36
97 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47 93.08
98 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38 93.08
99 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8 92.80
100 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08 92.80
101 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53 92.72
102 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64 92.36
103 INT186152 Camk4 Regulation of Phosphorylation of Creb1 3 0.27 0.44 0.29 92.36
104 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34 91.92
105 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29 91.56
106 INT134029 Olr696 Regulation of Ldha 1 0.00 0.15 0.68 91.20
107 INT134028 Olr696 Regulation of Trib3 1 0.00 0.15 0.68 90.80
108 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 90.68
109 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 90.64
110 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 90.56
111 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02 89.84
112 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5 89.84
113 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7 89.80
114 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61 89.80
115 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32 89.68
116 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 89.68
117 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45 89.56
118 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63 89.56
119 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57 89.56
120 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57 89.56
121 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57 89.56
122 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56 89.56
123 INT151895 Binding of CYP3A4 and GBE1 1 0.01 0.24 0.18 89.56
124 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 89.52
125 INT134027 Olr696 Regulation of Drp2 1 0.01 0.15 0.68 89.44
126 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24 89.28
127 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51 89.04
128 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41 89.04
129 INT290847 Regulation of Binding of Stx1a and Fig4 1 0.05 0.26 0.24 88.84
130 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22 88.76
131 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22 88.76
132 INT280490 Binding of Bdnf and Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.15 0.94 0.22 88.76
133 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 88.72
134 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56 88.60
135 INT317705 Gad2 Regulation of Gene_expression of Gabrg1 1 0.28 0.53 0.8 88.40
136 INT290846 Binding of Stx1a and Fig4 1 0.07 0.26 0.22 88.24
137 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55 87.88
138 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28 87.68
139 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27 87.68
140 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29 86.96
141 INT91119 ecs Regulation of Glra2 1 0.02 0.62 0.13 86.64
142 INT223927 Maoa Regulation of Positive_regulation of Cux1 1 0.24 0.1 0.27 86.40
143 INT141315 Gs Regulation of Kcnk10 1 0.16 0.64 0.27 86.16
144 INT141314 Gs Regulation of Kcnk4 1 0.19 0.64 0.27 86.16
145 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51 86.00
146 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88 85.92
147 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 85.84
148 INT40854 Man2a2 Regulation of Regulation of Eef1a1 1 0.03 0 0.25 85.20
149 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26 85.12
150 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26 85.12
151 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12 85.08
152 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79 84.92
153 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11 84.76
154 INT97868 Binding of Chrna2 and Regulation of Acot1 1 0.09 0 0.23 84.64
155 INT264569 Binding of STS and ATF7IP 1 0.03 0.15 0.25 84.56
156 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38 84.24
157 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79 83.96
158 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82 83.60
159 INT152111 IL1B Negative_regulation of Ltp 1 0.03 0.85 0.66 83.20
160 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6 82.64
161 INT111813 CREM Regulation of Regulation of CRH 1 0.12 0 0.3 82.48
162 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75 82.12
163 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37 81.80
164 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9 81.68
165 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9 81.04
166 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33 80.88
167 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16 79.68
168 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36 79.48
169 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37 79.00
170 INT290858 Positive_regulation of Ca2 Regulation of PPR 1 0.01 0.5 0.18 77.84
171 INT290856 Ca2 Regulation of PPR 1 0.01 0.5 0.18 77.32
172 INT143619 Bhlhe22 Positive_regulation of Regulation of Msr1 1 0.40 0.93 0.46 77.04
173 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 77.04
174 INT106691 Ngf Positive_regulation of SIGMAR1 1 0.04 0 0.74 76.84
175 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 76.60
176 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 76.60
177 INT286683 Gopc Positive_regulation of MBD2 1 0.01 1.07 0.11 76.40
178 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28 76.32
179 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49 75.76
180 INT235875 Bdnf Positive_regulation of Phosphorylation of Mapk1 1 0.09 0.38 0.17 75.24
181 INT192873 Binding of RS1 and Nktcn1 1 0.00 0.8 0.59 75.24
182 INT160156 Tph2 Regulation of Htr1a 1 0.30 0.75 0.56 75.04
183 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92 75.00
184 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91 75.00
185 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96 75.00
186 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96 75.00
187 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99 75.00
188 INT40855 GGH Regulation of PRL 1 0.10 0 0.32 75.00
189 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59 75.00
190 INT98726 Binding of Msr1 and Tacr2 1 0.00 0.06 0.42 75.00
191 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 75.00
192 INT108020 Binding of Adrb1 and Clec4d 1 0.00 1.19 0.61 75.00
193 INT108018 Binding of Slc37a4 and Clec4d 1 0.00 1.18 0.6 75.00
194 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 75.00
195 INT108021 Binding of Pomc and Mc4r 1 0.00 0.97 0.55 75.00
196 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89 75.00
197 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81 75.00
198 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53 75.00
199 INT37157 Pir Positive_regulation of Kncn 1 0.01 0.38 0.3 75.00
200 INT108019 Clec4d Negative_regulation of Binding of Pomc 1 0.00 0.44 0.28 75.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for antidepressant. They are ordered first by their pain relevance and then by number of times they were reported in antidepressant. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 100.00
2 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 100.00
3 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83 100.00
4 INT163479 Binding of Bdnf 36 0.48 25.77 14.83 100.00
5 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 100.00
6 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64 100.00
7 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 100.00
8 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 100.00
9 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 100.00
10 INT102023 Regulation of Creb1 51 0.62 16.29 16.71 100.00
11 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2 100.00
12 INT119411 Negative_regulation of Tst 22 0.38 7.84 7.63 100.00
13 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65 100.00
14 INT6177 Binding of Htr1a 65 0.47 17.65 30.59 100.00
15 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 100.00
16 INT144702 Gene_expression of Tst 19 0.68 12.87 4.04 100.00
17 INT16714 Regulation of Creb1 64 0.62 22.23 33.56 100.00
18 INT91475 Binding of NDOR1 3 0.27 0.61 4.97 100.00
19 INT40638 Binding of HRH1 14 0.44 5.81 5.09 100.00
20 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
21 INT57724 Regulation of Cux1 10 0.39 1.81 3.92 100.00
22 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
23 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 100.00
24 INT5452 Regulation of CRH 56 0.62 15.32 12.42 100.00
25 INT79396 Regulation of Gene_expression of Pde4a 6 0.59 1.45 4.12 100.00
26 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
27 INT150001 Positive_regulation of Agps 3 0.43 1.71 1.56 100.00
28 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 100.00
29 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23 100.00
30 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07 100.00
31 INT118492 Regulation of Pde4a 7 0.61 6.32 6.04 100.00
32 INT92971 Binding of Creb1 31 0.47 11.3 6.22 100.00
33 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
34 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78 100.00
35 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08 100.00
36 INT223920 Regulation of Gene_expression of Serpina1 1 0.05 0.4 1.57 100.00
37 INT79401 Regulation of Gene_expression of Pde4b 4 0.59 1.26 1.8 100.00
38 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93 100.00
39 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 100.00
40 INT228437 Regulation of Transcription of Mtpn 1 0.03 0.08 1.02 100.00
41 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 100.00
42 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13 100.00
43 INT29368 Binding of ECT 25 0.41 11.65 5.81 100.00
44 INT120865 Regulation of Cyp3a62 5 0.62 0.07 3.4 100.00
45 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76 100.00
46 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 100.00
47 INT160105 Binding of Tst 6 0.31 1.23 1.56 100.00
48 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05 100.00
49 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55 100.00
50 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56 100.00
51 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 100.00
52 INT61264 Regulation of Jun 36 0.61 18.42 8.71 100.00
53 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 100.00
54 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 100.00
55 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
56 INT180300 Positive_regulation of Positive_regulation of S100B 3 0.50 2.07 0.79 100.00
57 INT32176 Negative_regulation of Negative_regulation of Adrb1 2 0.40 0.4 1.77 100.00
58 INT296659 Regulation of Cds1 1 0.41 0.54 1.08 100.00
59 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
60 INT128273 Regulation of Gene_expression of Slc17a7 3 0.62 0.82 1.72 100.00
61 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
62 INT53639 Positive_regulation of Gene_expression of Ads1 1 0.40 1.85 0.93 100.00
63 INT22434 Gene_expression of Ads1 10 0.75 9.16 1.4 100.00
64 INT86680 Regulation of Pde4a 5 0.62 1.34 2.29 100.00
65 INT106582 Negative_regulation of Rabif 1 0.57 0.25 1.68 100.00
66 INT200979 Regulation of Gene_expression of UPF1 4 0.28 2.19 1.31 100.00
67 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 100.00
68 INT154727 Regulation of Cyp2b2 2 0.25 0 1.76 100.00
69 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
70 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25 100.00
71 INT343581 Negative_regulation of Gys1 1 0.03 0.23 0.81 100.00
72 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21 100.00
73 INT98310 Regulation of gr 21 0.39 15.04 6.68 100.00
74 INT79699 Regulation of Cyp2a 1 0.55 0.46 1.62 100.00
75 INT160521 Regulation of Enpp1 3 0.26 0.75 0.72 100.00
76 INT4616 Regulation of Maoa 40 0.62 6.09 15.94 100.00
77 INT242353 Binding of Tcas1 3 0.03 3.31 2.22 100.00
78 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
79 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8 100.00
80 INT63440 Regulation of Transcription of Npy 5 0.39 1.53 2.25 100.00
81 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15 100.00
82 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53 100.00
83 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13 100.00
84 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
85 INT64505 Localization of Htr2c 3 0.78 0.87 2.24 100.00
86 INT288625 Localization of MT2A 1 0.46 0.46 0.95 100.00
87 INT101340 Localization of MTNR1A 3 0.55 2.07 1.04 100.00
88 INT83073 Negative_regulation of Tyrp1 10 0.23 4.4 2.65 100.00
89 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 100.00
90 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
91 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8 100.00
92 INT3530 Regulation of BCHE 18 0.60 5.47 4.12 100.00
93 INT91994 Regulation of Gene_expression of Gfra1 5 0.42 6 3.6 100.00
94 INT15854 Regulation of Artles 4 0.01 2.52 2.35 100.00
95 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 100.00
96 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
97 INT6005 Gene_expression of Serpini1 5 0.58 1.62 4.74 100.00
98 INT223915 Positive_regulation of Regulation of Cux1 1 0.35 0 0.49 100.00
99 INT119757 Negative_regulation of SSR1 3 0.42 0.38 1.18 100.00
100 INT115578 Regulation of Gene_expression of Cux1 2 0.19 0.08 0.45 100.00
101 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06 100.00
102 INT98649 Regulation of Regulation of Ntf3 1 0.06 0.15 0.41 100.00
103 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55 100.00
104 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56 100.00
105 INT141173 Negative_regulation of Gene_expression of Nenf 1 0.25 0.09 0.67 100.00
106 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28 100.00
107 INT109344 Binding of PGP 4 0.37 0.35 0.54 100.00
108 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
109 INT89265 Regulation of Smpd4 2 0.44 1.56 1.28 100.00
110 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11 100.00
111 INT32124 Negative_regulation of ecs 10 0.37 6.53 3.81 100.00
112 INT24746 Negative_regulation of Binding of Abat 4 0.42 0.1 3.51 100.00
113 INT59679 Binding of Cyp2c6 3 0.48 0.2 1.14 100.00
114 INT133835 Regulation of Cyp2c6 1 0.45 0 0.69 100.00
115 INT128320 Regulation of Gene_expression of Npas2 1 0.43 0.18 1.38 100.00
116 INT139236 Regulation of Sgk1 2 0.37 0.84 1.14 100.00
117 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17 100.00
118 INT91993 Regulation of Gene_expression of Ret 3 0.42 2.42 0.55 100.00
119 INT6807 Regulation of Gabrd 39 0.62 9.22 18.74 100.00
120 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44 100.00
121 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65 100.00
122 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 100.00
123 INT75421 Regulation of Binding of Ptprg 13 0.44 0.96 12.64 100.00
124 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 100.00
125 INT83700 Regulation of Regulation of Htr7 1 0.60 0 0.3 100.00
126 INT115678 Regulation of Transcription of Semg1 1 0.12 0.09 0.65 100.00
127 INT115676 Regulation of Semg1 1 0.27 0.09 0.64 100.00
128 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45 100.00
129 INT57673 Regulation of Positive_regulation of htr 2 0.24 0.27 1.76 100.00
130 INT27258 Regulation of Htr2a 18 0.60 6.37 11.06 100.00
131 INT207172 Negative_regulation of Gene_expression of TM9SF2 1 0.41 0.95 0.33 100.00
132 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19 100.00
133 INT151777 Regulation of Gene_expression of P2rx1 3 0.60 1.97 1.48 100.00
134 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82 100.00
135 INT50571 Regulation of Gene_expression of Akr1d1 3 0.33 0.33 2.4 100.00
136 INT30590 Regulation of Phosphorylation of TNFSF14 1 0.44 0 0.47 100.00
137 INT97516 Binding of PYCARD 46 0.36 7.06 7.85 100.00
138 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24 100.00
139 INT93061 Binding of gr 31 0.48 10.93 6.45 100.00
140 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65 100.00
141 INT35910 Binding of Mme 8 0.37 4.79 3.16 100.00
142 INT31252 Gene_expression of Slc25a1 3 0.62 0.62 1.42 100.00
143 INT254289 Regulation of Ads1 2 0.26 1.14 0.38 100.00
144 INT29819 Regulation of Cdipt 1 0.03 0 0.25 100.00
145 INT79080 Regulation of Positive_regulation of Htr1a 4 0.44 0.08 2.56 100.00
146 INT79775 Binding of HCL1 2 0.03 0.98 1.59 100.00
147 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 100.00
148 INT128324 Regulation of Gene_expression of Per1 11 0.61 1.95 5.22 100.00
149 INT128327 Regulation of Gene_expression of Per2 9 0.45 1.11 1.66 100.00
150 INT128316 Regulation of Gene_expression of Arntl 6 0.43 0.68 1.43 100.00
151 INT128321 Regulation of Gene_expression of Cry1 2 0.34 0.09 1.38 100.00
152 INT128318 Regulation of Gene_expression of Aanat 1 0.33 0.09 0.76 100.00
153 INT128323 Regulation of Gene_expression of Per3 1 0.21 0.09 0.69 100.00
154 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68 100.00
155 INT129747 Regulation of Transcription of Nr3c1 1 0.22 0.53 0.48 100.00
156 INT15190 Regulation of Npy 17 0.61 5.33 5.84 100.00
157 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14 100.00
158 INT41495 Regulation of Sp1 7 0.42 2.96 2.05 100.00
159 INT151660 Regulation of Positive_regulation of gr 1 0.39 0.1 0.2 100.00
160 INT151659 Regulation of Positive_regulation of Nr3c1 1 0.03 0.1 0.2 100.00
161 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 100.00
162 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 100.00
163 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 100.00
164 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 100.00
165 INT164220 Gene_expression of OPN1SW 21 0.65 13.7 4.14 100.00
166 INT109573 Regulation of Ncl-ps1 1 0.08 0 0.25 100.00
167 INT91997 Regulation of Gene_expression of Gsk3a 1 0.03 0.56 0.1 100.00
168 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 99.98
169 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 99.98
170 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 99.98
171 INT43063 Positive_regulation of Cux1 3 0.49 1.57 7.13 99.98
172 INT115 Negative_regulation of Maoa 65 0.59 16.27 38.66 99.98
173 INT296660 Positive_regulation of Gene_expression of Cds1 1 0.40 2.1 6.55 99.98
174 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83 99.98
175 INT296661 Positive_regulation of Cds1 1 0.40 1.33 4.45 99.98
176 INT61238 Negative_regulation of Cyp2d2 4 0.58 0 6.38 99.98
177 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.98
178 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 99.98
179 INT145681 Regulation of P2rx4 4 0.61 3.41 5.09 99.98
180 INT223921 Positive_regulation of Gene_expression of Cux1 1 0.49 0.83 2.36 99.98
181 INT96557 Binding of Bdnf 46 0.47 21.74 24.26 99.98
182 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 99.98
183 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 99.98
184 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36 99.98
185 INT53395 Positive_regulation of Cyp2c6 6 0.70 0.07 3.73 99.98
186 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24 99.98
187 INT99438 Positive_regulation of Atf6b 12 0.49 4.28 5.97 99.98
188 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.98
189 INT142241 Positive_regulation of Positive_regulation of Ntrk2 3 0.66 0.87 1.43 99.98
190 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 99.98
191 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 99.98
192 INT135929 Positive_regulation of Pde4b 3 0.47 0.09 1.7 99.98
193 INT152743 Positive_regulation of Localization of BDNF 7 0.56 4.04 3.74 99.98
194 INT135927 Positive_regulation of Pde4a 1 0.68 0 1.6 99.98
195 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.98
196 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.98
197 INT10480 Positive_regulation of Ppp1r1b 15 0.70 2.82 9.97 99.98
198 INT223908 Positive_regulation of Positive_regulation of Cux1 1 0.40 0.07 0.67 99.98
199 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 99.98
200 INT223906 Positive_regulation of Gene_expression of Dgkb 1 0.45 0.54 1.2 99.98
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