P:antiepileptic Drug

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pChart

Pain Term
Category Drug class
Synonyms Antiepileptic Drugs
Pain Specific No
Documents 937
Hot Single Events 156
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for antiepileptic Drug. They are ordered first by their pain relevance and then by number of times they were reported for antiepileptic Drug. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 99.12
2 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92 98.80
3 INT326460 NR1I2 Regulation of Cyp4f18 1 0.01 0.72 0.18 92.84
4 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38 92.32
5 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15 82.32
6 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12 81.56
7 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08 76.68
8 INT244280 Binding of Tspo and Ptz1a 1 0.02 0.49 0.41 75.00
9 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23 72.72
10 INT262145 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.45 0.06 63.76
11 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 62.96
12 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 62.96
13 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 61.92
14 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 61.28
15 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 61.04
16 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 60.40
17 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09 59.68
18 INT197647 DPH1 Negative_regulation of VDR 1 0.02 0.58 0.18 50.00
19 INT197645 DPH1 Positive_regulation of SHBG 1 0.02 0.06 0.14 50.00
20 INT197644 NR1I2 Negative_regulation of Positive_regulation of CYP3A 1 0.02 0.47 0.08 50.00
21 INT197650 NR1I2 Negative_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 50.00
22 INT197652 NR1I2 Positive_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 50.00
23 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07 50.00
24 INT197648 ESRRB Positive_regulation of VDR 1 0.03 0.54 0.07 50.00
25 INT197646 DPH1 Negative_regulation of Localization of BGLAP 1 0.01 0.26 0.04 50.00
26 INT197651 TNF Regulation of PTH 1 0.05 1.67 0 50.00
27 INT197643 TNF Regulation of VDR 1 0.04 1.67 0 50.00
28 INT137647 PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15 48.16
29 INT137646 Negative_regulation of PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15 48.16
30 INT262170 Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.4 0 45.60
31 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08 30.48
32 INT264210 Binding of Aes and Igh-Lev 1 0.07 0.41 0 24.80
33 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27 14.80
34 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0 12.36
35 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
36 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98 5.00
37 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98 5.00
38 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
39 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92 5.00
40 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67 5.00
41 INT179237 Binding of SERPINA6 and POMC 1 0.03 1.15 0.49 5.00
42 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45 5.00
43 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44 5.00
44 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4 5.00
45 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38 5.00
46 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 5.00
47 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36 5.00
48 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36 5.00
49 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35 5.00
50 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34 5.00
51 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
52 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 5.00
53 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27 5.00
54 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27 5.00
55 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26 5.00
56 INT179233 IRF6 Negative_regulation of Binding of GSR 1 0.03 0.83 0.25 5.00
57 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25 5.00
58 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25 5.00
59 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25 5.00
60 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25 5.00
61 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25 5.00
62 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24 5.00
63 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24 5.00
64 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
65 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
66 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23 5.00
67 INT179229 Binding of GSR and NR3C2 1 0.03 0.37 0.23 5.00
68 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21 5.00
69 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
70 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2 5.00
71 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2 5.00
72 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14 5.00
73 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14 5.00
74 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13 5.00
75 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13 5.00
76 INT311111 Binding of Pcp4 and Calm2 1 0.11 0.57 0.13 5.00
77 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12 5.00
78 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12 5.00
79 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12 5.00
80 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12 5.00
81 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12 5.00
82 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11 5.00
83 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11 5.00
84 INT262141 Edcs1 Positive_regulation of Nr1i2 1 0.02 0 0.1 5.00
85 INT262163 Positive_regulation of Binding of Nr1i2 and Plec 1 0.04 0.31 0.09 5.00
86 INT262142 Edcs1 Regulation of Nr1i2 1 0.01 0 0.09 5.00
87 INT262157 Binding of Nr1i2 and Plec 1 0.03 0.3 0.09 5.00
88 INT262176 Nr1i2 Regulation of Regulation of Casr 1 0.11 0.17 0.07 5.00
89 INT262219 Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07 5.00
90 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07 5.00
91 INT262168 Nr1i2 Regulation of Casr 1 0.07 0.17 0.07 5.00
92 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 5.00
93 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07 5.00
94 INT262147 Nr1i2 Regulation of Gene_expression of Cyp2j8 1 0.00 0.07 0.07 5.00
95 INT262143 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07 5.00
96 INT179232 Binding of CREM and GSR 1 0.00 0 0.06 5.00
97 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06 5.00
98 INT262190 Foxo1 Positive_regulation of Pck1 1 0.04 0.15 0.06 5.00
99 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06 5.00
100 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06 5.00
101 INT262209 Positive_regulation of Nr1i2 Positive_regulation of Transcription of Ppig 1 0.03 0 0.06 5.00
102 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06 5.00
103 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05 5.00
104 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05 5.00
105 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05 5.00
106 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04 5.00
107 INT262221 Nr1i2 Negative_regulation of Cyp24a1 1 0.27 0.15 0.04 5.00
108 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04 5.00
109 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04 5.00
110 INT262162 Nr1i2 Regulation of Cyp2b9 1 0.14 0.14 0.03 5.00
111 INT262195 Nr1i2 Positive_regulation of Srebf1 1 0.08 0.18 0.03 5.00
112 INT262198 Foxo1 Positive_regulation of Igfbp1 1 0.11 0.08 0.03 5.00
113 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03 5.00
114 INT262171 Binding of Cyp3a11 and Rare1 1 0.02 0.15 0.03 5.00
115 INT262217 Casr Regulation of Cyp3a11 1 0.05 0.13 0.03 5.00
116 INT262149 Binding of Nfe2l2 and Rare1 1 0.03 0.32 0.03 5.00
117 INT262150 Binding of Rare1 and Sfn 1 0.01 0.33 0.03 5.00
118 INT262184 Binding of Nr1i2 and Rare1 1 0.03 0.15 0.03 5.00
119 INT203400 Olfm1 Negative_regulation of Bex1 1 0.09 0.58 0 5.00
120 INT203402 Enc1 Negative_regulation of Rtn1 1 0.07 0.58 0 5.00
121 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0 5.00
122 INT203405 Vsnl1 Negative_regulation of Bex1 1 0.19 0.58 0 5.00
123 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0 5.00
124 INT262203 Nr1i2 Positive_regulation of Gene_expression of Hmgcs2 1 0.23 0.22 0 5.00
125 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0 5.00
126 INT203411 Mllt11 Negative_regulation of Nptn 1 0.08 0.58 0 5.00
127 INT203418 Enc1 Negative_regulation of Rtn4 1 0.08 0.58 0 5.00
128 INT353189 Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0 5.00
129 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
130 INT354919 Uvbs1 Positive_regulation of Binding of VDR and Uvbs1 1 0.00 0.13 0 5.00
131 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0 5.00
132 INT203406 Cap2 Negative_regulation of Rtn4 1 0.07 0.59 0 5.00
133 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0 5.00
134 INT203414 Vsnl1 Negative_regulation of Nptn 1 0.16 0.58 0 5.00
135 INT262204 Nr1i2 Positive_regulation of Cyp3a11 1 0.33 0.08 0 5.00
136 INT203394 Vsnl1 Negative_regulation of Chn1 1 0.17 0.58 0 5.00
137 INT203410 Vsnl1 Negative_regulation of Rtn4 1 0.18 0.58 0 5.00
138 INT262225 Binding of CYP3A4 and Nr1i2 1 0.13 0 0 5.00
139 INT203398 Enc1 Negative_regulation of Nptn 1 0.07 0.59 0 5.00
140 INT203409 Cap2 Negative_regulation of Bex1 1 0.07 0.58 0 5.00
141 INT353197 ARNTL Regulation of Hlf 1 0.29 0.33 0 5.00
142 INT203417 Mllt11 Negative_regulation of Rtn1 1 0.08 0.58 0 5.00
143 INT353188 Ggh Regulation of Cux2 1 0.11 0.08 0 5.00
144 INT262213 Plec Positive_regulation of Cyp3a11 1 0.02 0 0 5.00
145 INT203415 Olfm1 Negative_regulation of Chn1 1 0.08 0.58 0 5.00
146 INT353191 Renbp Regulation of Gene_expression of Yif1 1 0.00 0.55 0 5.00
147 INT203408 Vsnl1 Negative_regulation of Cap2 1 0.15 0.58 0 5.00
148 INT353195 ARNTL Regulation of Gene_expression of Tef 1 0.22 0.33 0 5.00
149 INT203397 Enc1 Negative_regulation of Chn1 1 0.08 0.58 0 5.00
150 INT203416 Mllt11 Negative_regulation of Chn1 1 0.09 0.58 0 5.00
151 INT203393 Mllt11 Negative_regulation of Bex1 1 0.09 0.58 0 5.00
152 INT262215 Binding of Nr1i2 and Dnajc7 1 0.08 0.26 0 5.00
153 INT203392 Olfm1 Negative_regulation of Nptn 1 0.08 0.58 0 5.00
154 INT320848 Binding of Npc1 and Npc2 1 0.39 0 0 5.00
155 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 5.00
156 INT353199 Cux2 Regulation of Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0 5.00
157 INT203401 Vsnl1 Negative_regulation of Rtn1 1 0.17 0.58 0 5.00
158 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
159 INT353187 Ggh Regulation of Hoxa2 1 0.01 0.08 0 5.00
160 INT203407 Cap2 Negative_regulation of Nptn 1 0.06 0.59 0 5.00
161 INT262191 Binding of Nr1i2 and Foxo1 1 0.22 0.09 0 5.00
162 INT353196 ARNTL Regulation of Tef 1 0.36 0.32 0 5.00
163 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0 5.00
164 INT203403 Enc1 Negative_regulation of Bex1 1 0.08 0.58 0 5.00
165 INT353190 Stat5a Positive_regulation of Cyp2c11 1 0.31 0 0 5.00
166 INT203396 Mllt11 Negative_regulation of Rtn4 1 0.09 0.58 0 5.00
167 INT203399 Olfm1 Negative_regulation of Rtn4 1 0.09 0.58 0 5.00
168 INT203391 Olfm1 Negative_regulation of Rtn1 1 0.08 0.58 0 5.00
169 INT262156 Nr1i2 Negative_regulation of Gene_expression of Hmgcs2 1 0.22 0.22 0 5.00
170 INT262174 Binding of Casr and Foxo1 1 0.05 0.09 0 5.00
171 INT262192 Nr1i2 Regulation of Positive_regulation of Cyp3a11 1 0.32 0 0 5.00
172 INT262199 Binding of Cyp2b9 and Rare1 1 0.01 0.15 0 5.00
173 INT353198 ARNTL Regulation of Dbp 1 0.32 0.32 0 5.00
174 INT203413 Cap2 Negative_regulation of Rtn1 1 0.06 0.59 0 5.00
175 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0 5.00
176 INT203404 Cap2 Negative_regulation of Chn1 1 0.06 0.58 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for antiepileptic Drug. They are ordered first by their pain relevance and then by number of times they were reported in antiepileptic Drug. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2513 Binding of Napa 80 0.42 4.29 6.51 100.00
2 INT107057 Binding of Vti1b 1 0.24 0.16 1.18 100.00
3 INT78797 Regulation of Tmem132a 8 0.45 3.61 12.73 100.00
4 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22 99.98
5 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 99.98
6 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 99.86
7 INT12334 Positive_regulation of CYP3A 34 0.70 6.77 7.85 99.86
8 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 99.80
9 INT262332 Gene_expression of ruf 1 0.07 0.99 0.21 99.60
10 INT262348 Gene_expression of Lgsn 12 0.58 12.64 2.08 99.54
11 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 99.54
12 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 99.54
13 INT264207 Binding of Igh-Lev 1 0.25 4.13 1.07 99.52
14 INT128563 Binding of Mllt1 8 0.41 6.7 5.63 99.52
15 INT104909 Binding of Pias1 11 0.37 3.67 6.72 99.48
16 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.42
17 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38 99.34
18 INT151940 Positive_regulation of Igh-Lev 2 0.41 4.51 0.41 99.28
19 INT70785 Negative_regulation of Ubc 1 0.06 0.79 1.14 99.26
20 INT311479 Gene_expression of Mllt1 4 0.58 4.92 2.39 99.20
21 INT248253 Positive_regulation of Gene_expression of HSPG2 3 0.44 4.61 1.65 99.16
22 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98 99.14
23 INT79149 Gene_expression of CSE 26 0.58 11.76 14.16 99.12
24 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 99.12
25 INT264035 Regulation of Lgsn 5 0.39 6.2 0.86 99.12
26 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 99.10
27 INT3755 Positive_regulation of GBE1 29 0.40 8.99 8.91 99.08
28 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 99.04
29 INT251522 Positive_regulation of MED13L 1 0.35 0.82 0.11 99.04
30 INT251521 Positive_regulation of GDF1 1 0.14 0.82 0.1 99.04
31 INT97876 Gene_expression of Pias1 4 0.59 1.62 2.18 99.00
32 INT262343 Binding of Lgsn 6 0.32 10.1 1.65 98.96
33 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 98.88
34 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 98.82
35 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 98.76
36 INT8101 Binding of INCENP 42 0.31 16.2 6.68 98.76
37 INT262352 Localization of Lgsn 3 0.60 1.49 0.6 98.64
38 INT20499 Positive_regulation of EPHA8 1 0.41 0.54 0.27 98.64
39 INT311475 Regulation of Localization of Mllt1 1 0.39 1.1 0.94 98.42
40 INT542 Gene_expression of Fshb 14 0.75 5.22 3.24 98.24
41 INT117799 Positive_regulation of Glyr1 4 0.46 0.42 1.98 98.12
42 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 98.08
43 INT20999 Negative_regulation of Binding of Insrr 17 0.47 3.53 8.93 98.02
44 INT146340 Localization of Mllt1 10 0.69 4.6 5.45 97.96
45 INT546 Binding of ALB 311 0.48 85.98 60.14 97.96
46 INT4153 Binding of Insrr 109 0.40 17.99 72.15 97.86
47 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78 97.36
48 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 96.96
49 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 96.88
50 INT53460 Gene_expression of tn 13 0.66 7.97 5.2 96.56
51 INT53459 Negative_regulation of Gene_expression of tn 2 0.42 0.85 1.13 96.56
52 INT49813 Gene_expression of Ptz1a 5 0.49 2.8 2.39 96.00
53 INT13033 Regulation of Negative_regulation of Abat 4 0.27 0.61 2.97 95.98
54 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 95.92
55 INT173090 Regulation of INCENP 24 0.09 9.45 2.16 95.88
56 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 95.80
57 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 95.80
58 INT5359 Protein_catabolism of Abat 12 0.62 5.11 8.54 95.80
59 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 95.80
60 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 95.72
61 INT174925 Binding of Hspg2 3 0.05 1.11 0.24 95.60
62 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 95.56
63 INT299153 Negative_regulation of Tnc 2 0.42 8.14 0.98 95.56
64 INT27220 Binding of CYP3A5 4 0.47 0.53 0.73 95.52
65 INT313252 Gene_expression of Best1 1 0.05 0.39 0.42 95.48
66 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 95.36
67 INT20331 Positive_regulation of CYP1A2 31 0.69 8.6 5.92 95.24
68 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 95.12
69 INT2910 Regulation of Abat 169 0.62 36.95 153.53 95.12
70 INT215091 Regulation of Localization of Gopc 6 0.27 1.18 1.2 95.04
71 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29 94.96
72 INT12812 Regulation of Hrh3 10 0.51 1.07 2.95 94.96
73 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 94.50
74 INT139845 Negative_regulation of Cyp4f18 4 0.28 0.95 0.78 94.40
75 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 94.24
76 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 94.24
77 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01 94.20
78 INT67089 Positive_regulation of Ugt1a6a 4 0.27 0.34 1.9 93.64
79 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 93.36
80 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 93.36
81 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21 93.36
82 INT344061 Regulation of Esl1 1 0.04 0.9 0.82 92.84
83 INT311481 Positive_regulation of Positive_regulation of Ugt1a@ 1 0.03 0.38 0.77 92.80
84 INT311473 Positive_regulation of Ugt1a@ 1 0.04 0.38 0.7 92.80
85 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45 92.32
86 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 92.20
87 INT129695 Binding of Sv2a 6 0.47 4.96 2.51 92.16
88 INT6750 Positive_regulation of Klkb1 6 0.28 2.01 2.09 92.04
89 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 91.76
90 INT264206 Gene_expression of Igh-Lev 1 0.30 5.68 0.87 91.56
91 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 91.44
92 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27 91.32
93 INT311482 Negative_regulation of Positive_regulation of Mllt1 1 0.37 0.66 1.55 91.28
94 INT173693 Localization of Gopc 249 0.65 70.49 38.81 91.24
95 INT7035 Regulation of CGA 87 0.45 29.04 28.45 91.16
96 INT69471 Localization of CYP3A 6 0.73 0.07 1.69 91.12
97 INT311478 Positive_regulation of Mllt1 4 0.60 2.38 2.34 90.68
98 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 90.48
99 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53 89.96
100 INT38255 Localization of Chkb 32 0.80 10.98 11.07 89.96
101 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97 89.72
102 INT262340 Binding of TRIP10 6 0.36 1.45 0.96 89.20
103 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4 88.96
104 INT70595 Regulation of Pias1 1 0.53 0.34 1.66 88.88
105 INT253081 Positive_regulation of CYP2C18 1 0.16 0.08 0.16 88.84
106 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 88.36
107 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 88.36
108 INT282384 Negative_regulation of Gene_expression of Pain1 3 0.42 2.7 1.59 88.36
109 INT147873 Negative_regulation of Gene_expression of GRIN1 8 0.58 2.3 1.46 88.36
110 INT74688 Regulation of Nos1 55 0.62 22.16 25.3 88.24
111 INT17561 Localization of Car2 303 0.79 60.95 44.52 88.16
112 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63 88.00
113 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 88.00
114 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 88.00
115 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02 88.00
116 INT262344 Negative_regulation of Lgsn 4 0.37 3.6 0.67 87.88
117 INT262123 Gene_expression of Cyp24a1 17 0.67 6.67 1.38 87.76
118 INT136164 Positive_regulation of Ccbl1 1 0.27 0 0.76 87.68
119 INT154497 Gene_expression of Ptprq 3 0.04 0.91 1.31 87.40
120 INT244278 Protein_catabolism of Ptz1a 1 0.27 0.71 0.51 87.40
121 INT344060 Gene_expression of Esl1 1 0.06 3.65 1.09 87.28
122 INT344064 Localization of Esl1 1 0.06 1.25 0.35 87.28
123 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39 86.76
124 INT194380 Negative_regulation of Gene_expression of IL5 22 0.42 15.78 4.1 86.72
125 INT171021 Negative_regulation of IL5 18 0.41 14.74 3.39 86.72
126 INT311477 Positive_regulation of Negative_regulation of Mllt1 1 0.43 0.3 0.75 86.24
127 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 86.20
128 INT6315 Regulation of Rbfox2 3 0.01 1.45 2.5 85.76
129 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66 85.68
130 INT27627 Binding of Rac1 41 0.41 22.88 13.68 85.60
131 INT275877 Positive_regulation of Positive_regulation of Chkb 1 0.07 0.35 0.68 85.48
132 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 85.36
133 INT17312 Binding of HSPG2 30 0.41 33.01 4.88 85.36
134 INT311480 Negative_regulation of Mllt1 1 0.50 0.55 1.31 84.96
135 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 84.96
136 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 84.96
137 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 84.96
138 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 84.68
139 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 84.16
140 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 83.56
141 INT160642 Positive_regulation of Gene_expression of Vdr 5 0.62 1.61 0.42 83.44
142 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73 83.44
143 INT262040 Negative_regulation of Gene_expression of Vdr 1 0.25 0.26 0.21 83.44
144 INT230410 Negative_regulation of Gene_expression of TNFAIP1 3 0.16 3.67 0.63 83.36
145 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 83.08
146 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56 82.92
147 INT142488 Positive_regulation of Gene_expression of Chkb 7 0.23 4.09 4.54 82.32
148 INT254045 Gene_expression of TRIP10 4 0.29 3.04 1.67 82.24
149 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 82.16
150 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 81.96
151 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 81.92
152 INT263678 Negative_regulation of Igh-Lev 2 0.19 0.81 0.58 81.28
153 INT16851 Regulation of Localization of Gabrg1 34 0.39 4.34 22.29 81.00
154 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 80.56
155 INT262095 Positive_regulation of Gene_expression of Cyp24a1 1 0.40 2.58 0.44 80.48
156 INT171820 Localization of Fig4 144 0.65 27.38 20.88 80.28
157 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 79.68
158 INT311476 Positive_regulation of Positive_regulation of Mllt1 1 0.40 0.16 0.72 79.44
159 INT22532 Positive_regulation of Bsp 9 0.70 1.59 8.73 79.44
160 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61 79.36
161 INT177628 Protein_catabolism of SERPINA6 2 0.96 1.2 0.42 79.24
162 INT262063 Localization of Vdr 3 0.75 1.76 0.33 78.16
163 INT344063 Binding of Esl1 1 0.04 3.16 0.8 78.08
164 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1 77.88
165 INT311472 Negative_regulation of Localization of Mllt1 1 0.37 0.9 1.45 77.68
166 INT136168 Negative_regulation of Binding of Kat2a 1 0.29 0 0.4 77.44
167 INT136167 Negative_regulation of Binding of Ccbl1 1 0.25 0 0.39 77.44
168 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 77.00
169 INT136169 Binding of Ccbl1 1 0.22 0 0.39 76.76
170 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89 76.68
171 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 76.48
172 INT109559 Localization of Napa 16 0.61 1.3 2.42 76.08
173 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 75.92
174 INT143623 Binding of Dpysl2 7 0.48 3.18 3.93 75.20
175 INT221573 Gene_expression of Dpysl2 9 0.78 4.32 1.88 75.20
176 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05 75.12
177 INT57431 Binding of PIAS1 4 0.30 4.35 1.94 75.00
178 INT222892 Binding of CACNA2D2 2 0.23 2.78 2.42 75.00
179 INT164254 Gene_expression of Dnaja3 1 0.57 1.1 1.83 75.00
180 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 75.00
181 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 75.00
182 INT6881 Binding of Tspo 12 0.46 5.03 4.38 75.00
183 INT50581 Regulation of PPIG 26 0.55 8.96 4.32 75.00
184 INT115911 Negative_regulation of Hsd17b12 3 0.51 1.19 1.08 75.00
185 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 75.00
186 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 75.00
187 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 75.00
188 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 75.00
189 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 75.00
190 INT8481 Regulation of PIAS1 4 0.45 0.47 3.44 75.00
191 INT28188 Regulation of CYP2E1 11 0.62 0.48 2.03 75.00
192 INT72558 Regulation of CYP2C19 6 0.54 1.97 1.14 75.00
193 INT125781 Negative_regulation of Binding of Tspo 2 0.41 1.21 0.74 75.00
194 INT192679 Positive_regulation of Localization of Pain1 3 0.49 1.94 1.41 74.64
195 INT263713 Positive_regulation of Localization of GRIN1 2 0.49 0.41 0.31 74.64
196 INT116813 Gene_expression of Ppbp 5 0.66 2.28 1.84 74.48
197 INT6065 Localization of GRIN1 15 0.74 3.15 9.81 74.36
198 INT192680 Localization of Pain1 6 0.73 5.01 4.42 74.36
199 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 73.64
200 INT2212 Binding of Abat 89 0.48 18.36 63.99 73.40
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