P:aspirin

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pChart

Pain Term
Category Drug
Synonyms Acetylsalicylic Acid
Pain Specific No
Documents 10521
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for aspirin. They are ordered first by their pain relevance and then by number of times they were reported for aspirin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54 100.00
2 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76 100.00
3 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55 100.00
4 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4 100.00
5 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 100.00
6 INT271780 Zfp560 Negative_regulation of Cpox 1 0.00 0.62 0.86 100.00
7 INT296829 USE1 Regulation of CASP4 1 0.01 0.17 0.81 100.00
8 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55 100.00
9 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49 100.00
10 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51 100.00
11 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51 100.00
12 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57 100.00
13 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68 100.00
14 INT333165 Binding of asa and Col7a1 1 0.03 0.94 0.63 100.00
15 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68 100.00
16 INT296827 Binding of BGN and USE1 1 0.01 0 0.44 100.00
17 INT296831 Binding of CASP4 and USE1 1 0.01 0 0.43 100.00
18 INT273893 ARSA Positive_regulation of HSD11B1 1 0.00 0.61 0.4 100.00
19 INT197115 Binding of MCF2 and RETNLB 1 0.00 1.06 0.7 100.00
20 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 0.24 0 0.42 100.00
21 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45 100.00
22 INT333166 Tlx2 Positive_regulation of Gene_expression of Nos3 1 0.08 0.18 0.32 100.00
23 INT333155 Tlx2 Regulation of Gene_expression of Nos3 1 0.08 0.18 0.32 100.00
24 INT333152 Tlx2 Positive_regulation of Nos3 1 0.08 0.18 0.32 100.00
25 INT333167 Tlx2 Regulation of Nos3 1 0.08 0.18 0.32 100.00
26 INT333158 asa Positive_regulation of Nos3 1 0.11 0.18 0.32 100.00
27 INT333169 asa Positive_regulation of Gene_expression of Nos3 1 0.11 0.18 0.32 100.00
28 INT333164 asa Regulation of Nos3 1 0.11 0.18 0.32 100.00
29 INT333149 asa Regulation of Gene_expression of Nos3 1 0.11 0.18 0.32 100.00
30 INT333154 Tlx2 Regulation of Gene_expression of asa 1 0.07 0.18 0.32 100.00
31 INT333163 asa Regulation of Gene_expression of Tlx2 1 0.07 0.18 0.32 100.00
32 INT164263 TGM7 Negative_regulation of CCND3 1 0.04 1.08 0.54 100.00
33 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53 100.00
34 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53 100.00
35 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53 100.00
36 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58 100.00
37 INT333160 asa Negative_regulation of Gene_expression of Vcam1 1 0.19 0.71 0.5 100.00
38 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48 100.00
39 INT333151 asa Regulation of Gene_expression of Icam1 1 0.09 0.59 0.48 100.00
40 INT296828 USE1 Regulation of Gene_expression of BGN 1 0.01 0.17 0.37 100.00
41 INT296826 USE1 Regulation of Gene_expression of CASP4 1 0.02 0.17 0.37 100.00
42 INT296830 USE1 Regulation of BGN 1 0.00 0.17 0.37 100.00
43 INT333161 asa Negative_regulation of Positive_regulation of Vcam1 1 0.22 0.57 0.47 100.00
44 INT153796 NUBPL Negative_regulation of YWHAQ 1 0.02 0.69 0.64 100.00
45 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64 100.00
46 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38 100.00
47 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56 100.00
48 INT124742 ARSA Positive_regulation of Localization of CSF2 1 0.10 0.15 0.91 100.00
49 INT124743 ARSA Negative_regulation of PTGER2 1 0.03 0.15 0.85 100.00
50 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 0.03 0.15 0.85 100.00
51 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86 100.00
52 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52 100.00
53 INT157150 Positive_regulation of PTGIR Negative_regulation of Gene_expression of TNF 1 0.12 0.97 0.34 100.00
54 INT25113 RYBP Negative_regulation of Binding of PTGER2 1 0.05 0 1.02 100.00
55 INT243685 NDUFA2 Negative_regulation of Localization of RELA 1 0.07 0 0.09 100.00
56 INT106810 ZNF398 Positive_regulation of RECK 1 0.02 0.5 1.01 100.00
57 INT106809 ZNF398 Positive_regulation of Transcription of RECK 1 0.02 0.5 1.01 100.00
58 INT113560 Negative_regulation of Binding of FN1 and PLAUR 1 0.26 0.87 0.37 99.98
59 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37 99.98
60 INT113553 Negative_regulation of Binding of PLAU and PLAUR 1 0.36 0.87 0.37 99.98
61 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37 99.98
62 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37 99.98
63 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51 99.98
64 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53 99.98
65 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 0.02 1.37 0.38 99.98
66 INT94074 ARSA Regulation of Gene_expression of IK 1 0.01 0.06 0.27 99.96
67 INT108878 ZNF236 Regulation of Protein_catabolism of Nfkbia 1 0.00 0.38 0.26 99.96
68 INT108880 ZNF236 Regulation of Gene_expression of Nfkbia 1 0.00 0.38 0.26 99.96
69 INT108877 ZNF236 Regulation of Phosphorylation of Nfkbia 1 0.00 0.38 0.26 99.96
70 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79 99.92
71 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43 99.90
72 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38 99.90
73 INT273891 WDTC1 Positive_regulation of Gene_expression of SELP 1 0.00 0.45 0.15 99.84
74 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97 99.82
75 INT53470 Acsm3 Regulation of Ptgs1 1 0.15 0 0.42 99.80
76 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13 99.72
77 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6 99.72
78 INT25111 Binding of PTGDS and PLEKHM1 1 0.01 0 0.97 99.70
79 INT100681 Negative_regulation of IL13 Positive_regulation of STAT6 1 0.30 1.39 0.57 99.66
80 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41 99.66
81 INT139565 Negative_regulation of Binding of PLEK and Tbxa2r 1 0.01 0.57 0.19 99.64
82 INT25112 RYBP Negative_regulation of Binding of PLEKHM1 1 0.01 0 1.17 99.62
83 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25 99.60
84 INT243169 EGFL7 Positive_regulation of Gene_expression of PPBP 1 0.02 0.67 0.72 99.54
85 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57 99.50
86 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 99.46
87 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37 99.46
88 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08 99.42
89 INT100684 IL13 Positive_regulation of Positive_regulation of IL4 1 0.18 0.74 0.3 99.42
90 INT100675 IL13 Positive_regulation of IL4 1 0.18 0.73 0.3 99.42
91 INT243680 NDUFA2 Regulation of TNF 1 0.21 0.15 0.25 99.42
92 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41 99.40
93 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25 99.40
94 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25 99.40
95 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45 99.38
96 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48 99.36
97 INT139566 Binding of PLEK and Tbxa2r 1 0.01 1.14 0.38 99.36
98 INT25109 Negative_regulation of COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.16 99.36
99 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51 99.34
100 INT138925 Ifng Positive_regulation of Gene_expression of Cxcl9 1 0.25 0.32 0.25 99.34
101 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45 99.32
102 INT102380 Ptgs1 Negative_regulation of Binding of Tbxa2r 1 0.04 0.16 0.14 99.32
103 INT341816 Binding of CEP68 and Aia1 1 0.02 4.76 0.76 99.30
104 INT341794 Binding of SUGT1 and CEP68 1 0.00 1.1 0.33 99.30
105 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91 99.28
106 INT113556 Binding of FN1 and PLAUR 1 0.22 0.81 0.37 99.28
107 INT122502 TNF Positive_regulation of Localization of CAPN2 1 0.24 0.18 0.38 99.26
108 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77 99.24
109 INT100677 IL13 Positive_regulation of STAT6 1 0.36 1.95 0.81 99.22
110 INT100682 IL13 Positive_regulation of Positive_regulation of STAT6 1 0.26 0.74 0.3 99.22
111 INT100683 Negative_regulation of IL4 Positive_regulation of STAT6 1 0.30 0.65 0.27 99.18
112 INT53471 Binding of Ptgs1 and Acsm3 1 0.17 0 0.41 99.12
113 INT177784 PDCD2 Positive_regulation of ASNS 1 0.04 0.76 0.46 99.12
114 INT177791 PDCD2 Positive_regulation of ATF4 1 0.06 0.76 0.46 99.12
115 INT177782 PDCD2 Positive_regulation of MTHFD2 1 0.06 0.76 0.46 99.12
116 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64 99.12
117 INT319223 RS1 Regulation of Positive_regulation of FSIP1 1 0.05 0.42 0.05 99.12
118 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89 99.10
119 INT25114 COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.15 99.08
120 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31 99.08
121 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65 99.04
122 INT84861 Rps6ka3 Positive_regulation of Transcription of APRT 1 0.28 0.19 0.55 99.02
123 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48 98.92
124 INT243684 CXCL16 Negative_regulation of NDUFA2 1 0.01 0.07 0.1 98.92
125 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38 98.76
126 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26 98.76
127 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46 98.72
128 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46 98.72
129 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46 98.72
130 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46 98.72
131 INT168533 Binding of FSIP1 and Aia1 2 0.01 1.97 0.4 98.68
132 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24 98.68
133 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24 98.68
134 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6 98.56
135 INT319221 FSIP1 Regulation of ADAM33 1 0.31 1.47 0.29 98.40
136 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38 98.24
137 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 0.09 0.19 0.37 98.24
138 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16 98.24
139 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6 98.16
140 INT48162 RIMS3 Regulation of Localization of LTC4S 1 0.10 2.14 3.25 98.12
141 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 98.04
142 INT170585 PPARA Negative_regulation of DYM 1 0.03 0.07 0.14 98.04
143 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29 97.96
144 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61 97.92
145 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6 97.92
146 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 97.90
147 INT157147 LSS Positive_regulation of PTGIR 1 0.09 0.96 0.36 97.90
148 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46 97.84
149 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43 97.82
150 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76 97.76
151 INT110061 Binding of Alox5 and Cpox 1 0.28 0.37 0.23 97.56
152 INT108881 ZNF236 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.26 97.54
153 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95 97.24
154 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23 97.24
155 INT116293 Gm9662 Negative_regulation of Pparg Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.33 97.24
156 INT166841 ANXA1 Negative_regulation of Binding of ANXA1 and Nfkb1 1 0.33 0.85 0.48 97.24
157 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32 97.24
158 INT270996 TBXA2R Regulation of LTC4S 1 0.24 0.83 0.13 97.24
159 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38 97.12
160 INT134888 Negative_regulation of TNFRSF11A Negative_regulation of Gene_expression of CCL2 1 0.24 0.38 0.33 97.00
161 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37 96.96
162 INT243681 CXCL16 Negative_regulation of TNF 1 0.01 0.07 0.1 96.84
163 INT117309 HP Positive_regulation of Gast 1 0.00 0.9 0.51 96.64
164 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16 96.54
165 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42 96.48
166 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14 96.48
167 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96 96.48
168 INT76761 Kctd1 Negative_regulation of RFFL 1 0.00 0.5 0.63 96.40
169 INT197114 IL1B Regulation of Binding of MCF2 1 0.03 0.48 0.31 96.40
170 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07 96.36
171 INT168528 QRFP Regulation of FSIP1 2 0.07 1.32 0.93 96.36
172 INT157146 LSS Negative_regulation of Positive_regulation of TNF 1 0.25 1.08 0.21 96.36
173 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33 96.32
174 INT341813 Binding of SUGT1 and Aia1 1 0.00 0.48 0.16 96.26
175 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44 96.20
176 INT25110 RYBP Negative_regulation of MTHFS 1 0.02 0 0.92 96.20
177 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4 96.20
178 INT90750 Oprd1 Regulation of Positive_regulation of Gpd1 1 0.10 0.25 0.78 96.12
179 INT113558 Negative_regulation of NFKB1 Negative_regulation of Localization of PLAU 1 0.41 0.97 0.29 95.76
180 INT193215 Binding of CYSLTR1 and CYSLTR2 2 0.09 1.7 0.21 95.72
181 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01 95.68
182 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75 95.60
183 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49 95.52
184 INT193216 Binding of LTC4S and CYSLTR1 1 0.04 0.71 0.16 95.48
185 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 0.04 0.06 0.34 95.40
186 INT35666 MPZ Regulation of Gene_expression of TBXA2R 1 0.02 0.57 0.32 95.28
187 INT103869 Binding of IRF6 and Positive_regulation of Hmox1 1 0.10 0.27 0.21 95.20
188 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47 94.92
189 INT236147 Binding of Ins1 and Ptpn1 2 0.03 1.29 0.05 94.72
190 INT216711 P2RY1 Negative_regulation of P2RY12 1 0.28 0.09 0.16 94.60
191 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59 94.44
192 INT100679 IL4 Positive_regulation of Gene_expression of FCER2 1 0.34 0.61 0.26 94.40
193 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47 94.12
194 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47 94.12
195 INT195219 Binding of CPB2 and CSRP1 1 0.03 0.99 0.96 93.96
196 INT229041 Gene_expression of IL32 Negative_regulation of Gene_expression of PTGER2 1 0.01 1.17 0.38 93.96
197 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 93.72
198 INT56071 NFKB1 Positive_regulation of Gene_expression of IL1B 1 0.36 0.4 0.27 93.36
199 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3 93.24
200 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49 93.04

Single Events

The table below shows the top 200 pain related interactions that have been reported for aspirin. They are ordered first by their pain relevance and then by number of times they were reported in aspirin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
2 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 100.00
3 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 100.00
4 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 100.00
5 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 100.00
6 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52 100.00
7 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
8 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 100.00
9 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 100.00
10 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 100.00
11 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 100.00
12 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 100.00
13 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 100.00
14 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 100.00
15 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 100.00
16 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13 100.00
17 INT145888 Negative_regulation of Mthfd1 27 0.41 8.98 5.4 100.00
18 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29 100.00
19 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 100.00
20 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 100.00
21 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38 100.00
22 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 100.00
23 INT77852 Binding of Chd7 8 0.31 4.1 2.51 100.00
24 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 100.00
25 INT18412 Binding of PLEK 49 0.47 17.82 10.72 100.00
26 INT152779 Binding of Hdis 4 0.28 4.64 2.05 100.00
27 INT77290 Gene_expression of asa 15 0.33 10.17 4.97 100.00
28 INT20075 Negative_regulation of Cryz 2 0.38 0 3.11 100.00
29 INT302658 Binding of ARSA 1 0.07 0.92 1.53 100.00
30 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 100.00
31 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 100.00
32 INT118124 Binding of USE1 24 0.16 16.64 5.44 100.00
33 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77 100.00
34 INT37057 Gene_expression of Tlx2 12 0.76 7.98 2.38 100.00
35 INT15481 Positive_regulation of asa 13 0.39 6.12 8.24 100.00
36 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 100.00
37 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53 100.00
38 INT89104 Binding of TGFB1 29 0.44 13.67 5.12 100.00
39 INT55335 Binding of Cpox 49 0.34 15.48 18.46 100.00
40 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 100.00
41 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
42 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71 100.00
43 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 100.00
44 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 100.00
45 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 100.00
46 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 100.00
47 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
48 INT104298 Negative_regulation of ARSA 2 0.28 0.56 0.89 100.00
49 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17 100.00
50 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92 100.00
51 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 100.00
52 INT64806 Binding of asa 10 0.30 4.11 3.14 100.00
53 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 100.00
54 INT54102 Positive_regulation of Gene_expression of TFPI 14 0.49 6.67 3.54 100.00
55 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89 100.00
56 INT302660 Positive_regulation of Gene_expression of ARSA 1 0.10 0.88 0.77 100.00
57 INT96649 Gene_expression of ARSA 5 0.65 2.82 0.8 100.00
58 INT68592 Negative_regulation of asa 8 0.37 3.75 2.1 100.00
59 INT69966 Positive_regulation of Negative_regulation of CPOX 11 0.45 6.18 4.64 100.00
60 INT9077 Regulation of Tbxa2r 13 0.45 5.49 3.75 100.00
61 INT71230 Regulation of asa 11 0.55 4.75 5.97 100.00
62 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19 100.00
63 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27 100.00
64 INT164269 Gene_expression of TGM7 3 0.47 2.48 1.11 100.00
65 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 100.00
66 INT65538 Regulation of Positive_regulation of Nfkb1 17 0.51 8.31 6.5 100.00
67 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77 100.00
68 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2 100.00
69 INT105021 Binding of GOPC 187 0.40 60.39 20.38 100.00
70 INT99663 Negative_regulation of Negative_regulation of Cryz 1 0.28 0 0.87 100.00
71 INT45917 Regulation of Negative_regulation of MTHFS 1 0.44 0 1.02 100.00
72 INT336833 Binding of CACNG6 1 0.37 6.91 0.99 100.00
73 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
74 INT11894 Negative_regulation of Gene_expression of Ptger2 47 0.55 16.95 11.59 100.00
75 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05 100.00
76 INT102615 Positive_regulation of Gene_expression of Tgfa 5 0.44 3.93 1.17 100.00
77 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
78 INT51377 Localization of Hexb 10 0.80 3.02 2.8 100.00
79 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
80 INT302661 Negative_regulation of Negative_regulation of ARSA 1 0.08 0.13 0.44 100.00
81 INT53451 Regulation of TAT 6 0.44 3.07 1.61 100.00
82 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2 100.00
83 INT181152 Regulation of Tlx2 2 0.07 2.66 0.43 100.00
84 INT44305 Regulation of Klk1c12 1 0.44 0 0.66 100.00
85 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2 100.00
86 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 100.00
87 INT38160 Binding of Caf 6 0.37 3 5.1 100.00
88 INT166014 Negative_regulation of Negative_regulation of MCL1 1 0.33 0.63 0.61 100.00
89 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56 100.00
90 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7 100.00
91 INT237125 Protein_catabolism of exf 1 0.05 0 0.41 100.00
92 INT67653 Gene_expression of Om 46 0.36 15.28 13.32 100.00
93 INT30002 Negative_regulation of Negative_regulation of PLEK 3 0.42 0.76 1.12 100.00
94 INT93506 Negative_regulation of Gene_expression of Tyr 2 0.57 1.61 1.15 100.00
95 INT125542 Phosphorylation of Arsa 1 0.02 0.52 0.67 100.00
96 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 100.00
97 INT302663 Positive_regulation of ARSA 1 0.10 0.36 0.38 100.00
98 INT98595 Regulation of ILK 6 0.62 3.84 1.16 100.00
99 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 100.00
100 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1 100.00
101 INT99905 Negative_regulation of Negative_regulation of Cpox 11 0.35 7.01 4.37 100.00
102 INT74812 Negative_regulation of Positive_regulation of Cpox 17 0.34 10.1 9.94 100.00
103 INT5297 Regulation of IFNA2 20 0.56 10.81 5.13 100.00
104 INT289197 Localization of QPCT 3 0.15 0.53 0.62 100.00
105 INT5068 Binding of Mthfs 4 0.44 1.26 1.7 100.00
106 INT5592 Regulation of Regulation of Penk 36 0.62 4.37 24.02 100.00
107 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36 100.00
108 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01 100.00
109 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
110 INT29836 Regulation of MTHFS 6 0.33 1.43 1.67 100.00
111 INT76736 Localization of asa 2 0.24 0.48 1.22 100.00
112 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 100.00
113 INT53468 Binding of Acsm3 26 0.24 20.87 2.95 100.00
114 INT77295 Positive_regulation of Tgfa 2 0.34 0.05 0.8 100.00
115 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 100.00
116 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09 100.00
117 INT181267 Gene_expression of USE1 12 0.32 7.6 2.7 100.00
118 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66 100.00
119 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 100.00
120 INT60589 Positive_regulation of Positive_regulation of Gbf1 4 0.39 1.7 1.59 100.00
121 INT6484 Binding of IL1B 122 0.47 75.84 35.07 100.00
122 INT76737 Positive_regulation of Localization of asa 1 0.03 0 0.35 100.00
123 INT98208 Regulation of Vwf 3 0.08 1.14 0.63 100.00
124 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93 100.00
125 INT63284 Transcription of Ptgs1 5 0.66 1.34 0.97 100.00
126 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46 100.00
127 INT104297 Regulation of ARSA 1 0.18 1.05 0.49 100.00
128 INT68654 Negative_regulation of RASD1 1 0.04 0.69 0.43 100.00
129 INT3598 Regulation of Pla2g1b 12 0.44 3.45 3.9 100.00
130 INT160708 Regulation of Positive_regulation of CD63 1 0.56 0.19 0.38 100.00
131 INT160707 Regulation of Positive_regulation of Enpp3 1 0.13 0.19 0.38 100.00
132 INT160705 Positive_regulation of Enpp3 2 0.20 1.26 0.56 100.00
133 INT91319 Positive_regulation of CD63 6 0.63 3.86 2.76 100.00
134 INT27446 Negative_regulation of CTSA 11 0.57 5.58 3.08 100.00
135 INT45916 Regulation of Negative_regulation of PLEK 1 0.44 0 0.54 100.00
136 INT106813 Positive_regulation of RECK 1 0.69 2.39 5.38 100.00
137 INT243692 Regulation of Binding of LRRC23 1 0.13 0.19 0.39 100.00
138 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 100.00
139 INT46428 Binding of LRRC23 3 0.23 0.36 0.61 100.00
140 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 100.00
141 INT144061 Regulation of Binding of Caf 1 0.12 1.1 0.62 100.00
142 INT22655 Regulation of Hrasls 4 0.36 3.77 2.23 100.00
143 INT60541 Regulation of GSTK1 12 0.61 6.76 3.31 100.00
144 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02 100.00
145 INT284164 Localization of Chd7 3 0.25 1.32 0.41 100.00
146 INT44309 Regulation of Localization of Klk1c12 1 0.44 0 0.38 100.00
147 INT243698 Phosphorylation of LRRC23 1 0.23 0.22 0.36 100.00
148 INT243699 Phosphorylation of NDUFA2 1 0.29 0.22 0.36 100.00
149 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 100.00
150 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47 100.00
151 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27 100.00
152 INT114787 Negative_regulation of Negative_regulation of Hmox2 1 0.01 0.93 1.6 100.00
153 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 100.00
154 INT92130 Regulation of F3 3 0.44 1.31 0.62 100.00
155 INT69991 Negative_regulation of Gene_expression of Hmox2 3 0.04 2.05 2.51 100.00
156 INT144092 Localization of Nono 1 0.29 0.5 0.57 100.00
157 INT1924 Regulation of PLAT 11 0.60 6.3 3.16 100.00
158 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 100.00
159 INT344682 Positive_regulation of Localization of Niacr1 1 0.28 1.27 0.35 100.00
160 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 100.00
161 INT34591 Regulation of Localization of ALPP 5 0.53 1.81 2.86 100.00
162 INT98497 Regulation of PAPPA 5 0.44 3.18 1.74 100.00
163 INT131320 Negative_regulation of Regulation of asa 1 0.02 0.87 0.56 100.00
164 INT2638 Regulation of PON1 5 0.59 5.13 0.45 100.00
165 INT68496 Binding of PGR 26 0.48 16.36 2.09 100.00
166 INT20462 Binding of ESR1 210 0.44 102.7 26.34 100.00
167 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 100.00
168 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63 100.00
169 INT28424 Regulation of Cysltr1 17 0.41 7.33 6.34 100.00
170 INT39679 Regulation of Atrn 8 0.11 1.29 2.22 100.00
171 INT245945 Localization of CAP1 4 0.69 1.63 1.95 100.00
172 INT23606 Regulation of Atp2b4 10 0.25 3.33 1.63 100.00
173 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5 100.00
174 INT33740 Negative_regulation of Binding of ANGPTL5 12 0.39 2.36 1.34 100.00
175 INT135713 Regulation of MIA2 1 0.13 0.68 1.1 100.00
176 INT63423 Negative_regulation of Gene_expression of SELP 13 0.55 1.98 0.57 100.00
177 INT35528 Negative_regulation of Eef1a2 7 0.38 2.6 1.34 100.00
178 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57 100.00
179 INT44304 Regulation of Gene_expression of Klk1c12 1 0.44 0 0.28 100.00
180 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 100.00
181 INT44428 Negative_regulation of SPANXB2 1 0.37 0 0.44 100.00
182 INT21167 Regulation of NCF1 3 0.15 0.75 1.24 100.00
183 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78 100.00
184 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06 100.00
185 INT94030 Binding of Nefh 3 0.48 1.93 1.57 100.00
186 INT6599 Binding of ITGA2 4 0.35 3.6 1.16 100.00
187 INT101737 Binding of Ugt1a6a 2 0.32 0.81 1.22 100.00
188 INT157156 Negative_regulation of Positive_regulation of PTGIR 1 0.12 1.78 0.71 100.00
189 INT119346 Positive_regulation of PTGIR 9 0.58 6.2 1.61 100.00
190 INT1136 Regulation of Atp6v0a1 3 0.29 0.2 0.65 100.00
191 INT16345 Regulation of Gene_expression of CASP4 3 0.26 0.42 1.08 100.00
192 INT9076 Regulation of Gene_expression of Tbxa2r 7 0.61 1.16 1.92 100.00
193 INT5021 Regulation of Lgals3 7 0.58 2.08 1.86 100.00
194 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 100.00
195 INT44122 Positive_regulation of AMPD1 4 0.44 1.88 0.92 100.00
196 INT26640 Regulation of Pigm 17 0.35 3.94 7.02 100.00
197 INT74243 Regulation of Regulation of Pigm 1 0.03 0.25 0.27 100.00
198 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28 100.00
199 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29 100.00
200 INT96863 Transcription of ACE 3 0.69 0.38 0.29 100.00
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