P:beta blocker

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pChart

Pain Term
Category Drug class
Synonyms Beta Blockers, Beta-blocker, Beta-blockers
Pain Specific No
Documents 2844
Hot Single Events 200
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for beta blocker. They are ordered first by their pain relevance and then by number of times they were reported for beta blocker. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT335565 Binding of KDM5D and SPNS1 1 0.02 0 0.13 94.32
2 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 83.36
3 INT352385 MIR27A Regulation of Foxo1 1 0.45 0.48 0.04 83.36
4 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 82.24
5 INT352368 MIR20B Regulation of VEGFA 1 0.08 0.44 0.04 77.84
6 INT174892 Binding of ADRB3 and ENPP3 1 0.04 0.4 0.14 75.28
7 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36 74.92
8 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32 73.68
9 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32 73.68
10 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37 72.80
11 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 68.20
12 INT180980 UROD Positive_regulation of Pcts 1 0.04 0.55 0.1 65.76
13 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 61.92
14 INT191899 Binding of EXOSC10 and PNN 1 0.00 0.96 0.03 61.12
15 INT345289 CRS Regulation of REN 1 0.03 1.02 0.12 58.40
16 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05 55.12
17 INT353861 Binding of Mgp and Phdlc1 1 0.01 5.09 0.16 52.40
18 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03 51.60
19 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 51.60
20 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21 47.16
21 INT334894 Binding of CALCR and ARMC9 1 0.01 0.41 0 43.44
22 INT213160 AGT Positive_regulation of Gene_expression of LEP 1 0.08 1.29 0.03 26.08
23 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 23.68
24 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 21.32
25 INT229245 Positive_regulation of Binding of FAS and Tnf 1 0.25 0.92 0.17 20.16
26 INT229246 Binding of FAS and Tnf 1 0.19 0.91 0.17 20.16
27 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17 19.76
28 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17 19.76
29 INT352381 Mir21 Regulation of Ephb1 1 0.02 0 0.03 13.44
30 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 8.16
31 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 7.32
32 INT316371 Ang Negative_regulation of Ren1 1 0.16 0.64 0.05 6.24
33 INT349663 Binding of TFPI and PYCARD 1 0.04 0 0.04 5.40
34 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
35 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 5.00
36 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
37 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 5.00
38 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
39 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
40 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
41 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
42 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
43 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
44 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
45 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53 5.00
46 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
47 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
48 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
49 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43 5.00
50 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43 5.00
51 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
52 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37 5.00
53 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
54 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34 5.00
55 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
56 INT282202 Tcas1 Negative_regulation of NA 1 0.01 0.32 0.34 5.00
57 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
58 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
59 INT171678 PPY Regulation of CISD1 1 0.00 0.33 0.33 5.00
60 INT171679 PPY Regulation of PRKCA 1 0.08 0.33 0.33 5.00
61 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
62 INT171677 PRKCA Regulation of CISD1 1 0.00 0 0.33 5.00
63 INT171680 PPY Regulation of MAPK4 1 0.02 0.33 0.33 5.00
64 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32 5.00
65 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
66 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 5.00
67 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 5.00
68 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
69 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
70 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
71 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 5.00
72 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 5.00
73 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26 5.00
74 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24 5.00
75 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24 5.00
76 INT123462 Binding of TNF and Tnfrsf11b 3 0.21 3.52 0.24 5.00
77 INT316375 Ang Positive_regulation of Nfkb1 1 0.08 0.73 0.23 5.00
78 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
79 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
80 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22 5.00
81 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
82 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
83 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
84 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
85 INT349668 Binding of HRH1 and PYCARD 1 0.00 0.37 0.21 5.00
86 INT239236 Prkca Regulation of CYBB 1 0.00 0.98 0.2 5.00
87 INT239235 Prkca Positive_regulation of Prkca Regulation of Nos3 1 0.01 0.97 0.2 5.00
88 INT239227 Prkca Regulation of Nos3 1 0.02 0.97 0.2 5.00
89 INT316370 Ang Positive_regulation of Xdh 1 0.07 0.62 0.2 5.00
90 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19 5.00
91 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19 5.00
92 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
93 INT337762 Tnf Regulation of Gene_expression of Tlr4 1 0.49 1.16 0.18 5.00
94 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
95 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17 5.00
96 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17 5.00
97 INT316376 Binding of Ang and Atp6ap2 1 0.06 0.87 0.16 5.00
98 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15 5.00
99 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
100 INT272024 Gene_expression of GOPC Positive_regulation of Localization of COL7A1 1 0.10 0.86 0.14 5.00
101 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
102 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 5.00
103 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14 5.00
104 INT291967 INA Positive_regulation of NA 1 0.00 0.98 0.14 5.00
105 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
106 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
107 INT256020 Ace Negative_regulation of Gene_expression of Agtr2 1 0.03 0.37 0.13 5.00
108 INT256021 Ace Negative_regulation of Gene_expression of Agtrap 1 0.05 0.37 0.13 5.00
109 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 5.00
110 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13 5.00
111 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
112 INT313913 Binding of Il23a and Il23r 1 0.24 0.43 0.13 5.00
113 INT313914 Binding of Il12a and Il23r 1 0.14 0.44 0.13 5.00
114 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
115 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
116 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
117 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12 5.00
118 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
119 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 5.00
120 INT316372 Positive_regulation of Gopc Positive_regulation of Ren1 1 0.06 0.13 0.11 5.00
121 INT316374 Gopc Positive_regulation of Ren1 1 0.06 0.13 0.11 5.00
122 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 5.00
123 INT316377 Gopc Positive_regulation of Positive_regulation of Ren1 1 0.06 0.13 0.11 5.00
124 INT256023 Lnpep Regulation of Gene_expression of Agt 1 0.18 0.14 0.1 5.00
125 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
126 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
127 INT286432 Binding of ANTXR2 and Gtf3a 1 0.00 3.56 0.1 5.00
128 INT256022 Lnpep Regulation of Oxt 1 0.15 0.14 0.1 5.00
129 INT256029 Lnpep Regulation of Agt 1 0.18 0.14 0.1 5.00
130 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
131 INT256017 Lnpep Regulation of Avp 1 0.01 0.14 0.1 5.00
132 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 5.00
133 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09 5.00
134 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 5.00
135 INT256018 Agt Positive_regulation of Oxt 1 0.12 0.31 0.09 5.00
136 INT256030 Agt Negative_regulation of Lnpep Positive_regulation of Oxt 1 0.07 0.31 0.09 5.00
137 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 5.00
138 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08 5.00
139 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08 5.00
140 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
141 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
142 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07 5.00
143 INT221878 Binding of Ltp and Ctrcts 1 0.00 1.94 0.07 5.00
144 INT256026 Binding of Agt and Oxt 1 0.07 0.92 0.07 5.00
145 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07 5.00
146 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 5.00
147 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05 5.00
148 INT197741 Binding of Rdh5 and Positive_regulation of PPARA 1 0.27 0.95 0.05 5.00
149 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
150 INT229711 Positive_regulation of Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 5.00
151 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
152 INT256024 Binding of Agt and Slc1a5 1 0.01 0.36 0.05 5.00
153 INT349665 Positive_regulation of Binding of AR and TFPI 1 0.02 0 0.05 5.00
154 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
155 INT229712 Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 5.00
156 INT349667 Binding of AR and TFPI 1 0.02 0 0.05 5.00
157 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
158 INT266445 Binding of HEY1 and GOPC 1 0.00 2.92 0.04 5.00
159 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
160 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
161 INT266452 Binding of Acot1 and GOPC 1 0.02 1.23 0.04 5.00
162 INT266454 Binding of HEY1 and Acot1 1 0.00 1.19 0.04 5.00
163 INT283202 Gm4658 Positive_regulation of Gene_expression of DMD 1 0.01 0.33 0.03 5.00
164 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03 5.00
165 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 5.00
166 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03 5.00
167 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
168 INT353865 Binding of CHI3L1 and Lepr 1 0.00 1.88 0.03 5.00
169 INT349661 PYCARD Positive_regulation of AR 1 0.08 0 0.03 5.00
170 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03 5.00
171 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
172 INT321189 SPEF1 Regulation of Gene_expression of DSE 1 0.09 0.97 0.03 5.00
173 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03 5.00
174 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03 5.00
175 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03 5.00
176 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 5.00
177 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
178 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0 5.00
179 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 5.00
180 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 5.00
181 INT256016 Binding of Oxt and Lnpep 1 0.11 0.64 0 5.00
182 INT286433 Negative_regulation of Binding of Shbg and ANTXR2 1 0.06 1.29 0 5.00
183 INT229713 Binding of Agt and Ren 1 0.14 0 0 5.00
184 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0 5.00
185 INT278293 Binding of DBP and SHBG 2 0.02 1.34 0 5.00
186 INT345287 Binding of SCN10A and RAPGEF5 1 0.01 0.67 0 5.00
187 INT349666 Binding of AR and PYCARD 1 0.06 0 0 5.00
188 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 5.00
189 INT229714 Positive_regulation of Binding of Agt and Ren 1 0.18 0 0 5.00
190 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 5.00
191 INT285231 Binding of CHKB and TNNT1 1 0.15 0.05 0 5.00
192 INT316373 Binding of Ren1 and Gopc 1 0.05 0.44 0 5.00
193 INT266453 SNRNP70 Regulation of Acot1 1 0.00 0.53 0 5.00
194 INT286434 Binding of Shbg and ANTXR2 1 0.05 1.29 0 5.00
195 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0 5.00
196 INT191900 Binding of EXOSC10 and COPD 1 0.01 0.53 0 5.00
197 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0 5.00
198 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0 5.00
199 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0 5.00
200 INT273518 Binding of ALB and NBN 1 0.06 0.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for beta blocker. They are ordered first by their pain relevance and then by number of times they were reported in beta blocker. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22 100.00
2 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55 100.00
3 INT274178 Binding of BBS2 1 0.27 2.12 0.82 100.00
4 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06 100.00
5 INT28236 Localization of BBS2 2 0.54 1.9 0.83 100.00
6 INT274177 Positive_regulation of Gene_expression of BBS2 2 0.36 1.55 0.49 100.00
7 INT2140 Regulation of REN 104 0.62 28.24 24.49 100.00
8 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93 100.00
9 INT274176 Negative_regulation of Gene_expression of BBS2 1 0.31 0.94 0.29 100.00
10 INT272845 Transcription of BBS2 1 0.04 0.42 0.16 100.00
11 INT26477 Regulation of ACE 26 0.45 16.31 4.33 100.00
12 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29 100.00
13 INT96863 Transcription of ACE 3 0.69 0.38 0.29 100.00
14 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 100.00
15 INT163516 Negative_regulation of Positive_regulation of PRB1 1 0.15 0.08 0.45 100.00
16 INT308557 Gene_expression of VPS45 1 0.66 1.12 0.4 100.00
17 INT23884 Negative_regulation of Negative_regulation of Adrb1 7 0.38 2.3 1.83 100.00
18 INT28484 Regulation of Cog1 6 0.43 4.96 0.71 100.00
19 INT7459 Positive_regulation of Lpl 15 0.70 6.96 1.81 100.00
20 INT18773 Localization of ALB 117 0.80 69.18 13.8 100.00
21 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 100.00
22 INT17818 Gene_expression of Agtr2 24 0.56 12.96 4.41 100.00
23 INT68099 Positive_regulation of Agtr2 21 0.48 16.63 4.07 100.00
24 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 99.98
25 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 99.98
26 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1 99.98
27 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 99.98
28 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.96
29 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 99.96
30 INT35528 Negative_regulation of Eef1a2 7 0.38 2.6 1.34 99.96
31 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.92
32 INT12061 Negative_regulation of LNPEP 19 0.58 5.52 2.14 99.92
33 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56 99.88
34 INT97882 Positive_regulation of ANXA13 1 0.49 0.23 0.45 99.88
35 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 99.84
36 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 99.84
37 INT81972 Positive_regulation of Dse 20 0.57 16.5 2.99 99.84
38 INT66776 Negative_regulation of Kcne2 6 0.35 2.48 0.33 99.84
39 INT661 Gene_expression of REN 100 0.78 48.21 11.36 99.80
40 INT65135 Binding of CYP2C19 17 0.48 1.82 5.2 99.76
41 INT34154 Regulation of Gene_expression of Atp7b 1 0.00 0.28 0.44 99.74
42 INT25391 Negative_regulation of Localization of Pbk 1 0.31 0.17 0.54 99.74
43 INT18121 Binding of Maoa 20 0.48 2.4 9.3 99.72
44 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37 99.68
45 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 99.68
46 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 99.66
47 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53 99.64
48 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.62
49 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.54
50 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 99.52
51 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 99.52
52 INT15255 Negative_regulation of Positive_regulation of PLAT 3 0.46 0.87 0.2 99.52
53 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 99.50
54 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.48
55 INT3533 Binding of REN 24 0.37 10.84 2.16 99.48
56 INT25389 Localization of Pbk 2 0.51 0.17 1.22 99.46
57 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2 99.44
58 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93 99.44
59 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 99.34
60 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 99.30
61 INT251 Regulation of INS 398 0.62 232.47 55.04 99.28
62 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 99.28
63 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 99.28
64 INT75908 Regulation of LEP 77 0.60 60.16 15.19 99.22
65 INT34586 Positive_regulation of Negative_regulation of HSD11B1 6 0.49 4.39 1.05 99.18
66 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 99.14
67 INT178889 Negative_regulation of CHDH 38 0.48 36.69 1.53 99.10
68 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 99.04
69 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73 99.04
70 INT288847 Negative_regulation of Positive_regulation of CHDH 1 0.11 0.1 0.1 98.92
71 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78 98.88
72 INT83826 Negative_regulation of Binding of Adrb1 3 0.25 0.67 0.6 98.88
73 INT11897 Gene_expression of Atp7b 25 0.13 7.85 12.5 98.86
74 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 98.84
75 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 98.80
76 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 98.76
77 INT2613 Negative_regulation of Positive_regulation of Ren 16 0.59 8.2 5.62 98.76
78 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07 98.74
79 INT84978 Positive_regulation of CHDH 21 0.50 21.97 0.48 98.70
80 INT24029 Regulation of AFP 7 0.44 6.45 0.51 98.68
81 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 98.64
82 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96 98.64
83 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 98.60
84 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 98.56
85 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 98.56
86 INT15775 Positive_regulation of Ren1 50 0.69 22.38 6.19 98.56
87 INT63951 Negative_regulation of Localization of Rab8a 1 0.38 0.16 0.57 98.54
88 INT191904 Positive_regulation of EXOSC10 11 0.06 5.43 0.57 98.52
89 INT48 Positive_regulation of Localization of Ren 69 0.70 12.47 18.03 98.50
90 INT465 Binding of Adrb1 14 0.35 3.04 4.07 98.48
91 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 98.48
92 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 98.42
93 INT70496 Positive_regulation of EFS 3 0.29 0.2 0.84 98.42
94 INT10166 Localization of Tnf 237 0.81 153.95 88.64 98.40
95 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 98.40
96 INT41985 Regulation of Regulation of HSD11B1 2 0.44 1.6 0.17 98.40
97 INT191905 Binding of EXOSC10 19 0.04 11.24 0.57 98.38
98 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 98.34
99 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 98.32
100 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 98.32
101 INT164632 Positive_regulation of EGFL7 8 0.32 3.03 0.71 98.30
102 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 98.28
103 INT46 Localization of Ren 233 0.81 46.15 62.44 98.28
104 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12 98.28
105 INT45112 Positive_regulation of PRB1 20 0.60 6.49 2.85 98.24
106 INT4495 Gene_expression of Adrb1 7 0.66 2.43 2.29 98.22
107 INT241790 Negative_regulation of AVPR1A 6 0.57 4.62 0.35 98.22
108 INT107407 Regulation of KCNE1 3 0.39 2.18 0.88 98.20
109 INT22080 Regulation of ras 40 0.53 36.24 4.44 98.20
110 INT273525 Regulation of NBN 1 0.49 1.28 0.05 98.20
111 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 98.16
112 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21 98.16
113 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94 98.16
114 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 98.14
115 INT30870 Negative_regulation of Adra2b 8 0.44 4.5 2.8 98.08
116 INT7116 Localization of Rab8a 10 0.70 1.2 1.95 98.06
117 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 97.96
118 INT43091 Positive_regulation of Negative_regulation of Ace 3 0.30 1.51 0.48 97.94
119 INT106805 Localization of ACCS 15 0.53 15.22 3.98 97.84
120 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86 97.68
121 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 97.68
122 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34 97.68
123 INT3084 Negative_regulation of Negative_regulation of REN 6 0.42 2.2 1.68 97.66
124 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 97.66
125 INT41621 Negative_regulation of Positive_regulation of Ren1 2 0.43 0.6 0.18 97.64
126 INT233916 Positive_regulation of AGTR2 5 0.37 3.67 0.51 97.56
127 INT70970 Binding of COPD 144 0.42 180.34 18.29 97.52
128 INT20664 Binding of ACE 60 0.48 35.27 9.16 97.52
129 INT191908 Negative_regulation of Positive_regulation of EXOSC10 1 0.01 0.25 0.09 97.52
130 INT7346 Localization of Hrh2 15 0.69 5.78 4.79 97.52
131 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 97.50
132 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95 97.42
133 INT92245 Negative_regulation of Fgg 13 0.06 9.68 1.35 97.42
134 INT103852 Negative_regulation of Thbd 2 0.10 2.03 0.26 97.42
135 INT38479 Positive_regulation of Kcne2 4 0.40 1 0.63 97.40
136 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3 97.36
137 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44 97.28
138 INT97516 Binding of PYCARD 46 0.36 7.06 7.85 97.28
139 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 97.28
140 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 97.20
141 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 97.20
142 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 97.20
143 INT41984 Regulation of Gene_expression of HSD11B1 4 0.44 4.18 0.23 97.20
144 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 97.16
145 INT345973 Binding of EVL 1 0.07 1.4 0.14 97.16
146 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 97.12
147 INT158 Localization of Prl 2431 0.81 378.96 952.2 97.00
148 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31 96.92
149 INT44874 Regulation of LCAT 1 0.62 0.15 1 96.84
150 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 96.80
151 INT291813 Negative_regulation of HSD17B4 3 0.42 0.62 0.17 96.80
152 INT31326 Binding of TREH 7 0.17 2.29 1.14 96.72
153 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 96.68
154 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68 96.64
155 INT654 Localization of REN 250 0.81 75.12 47.86 96.58
156 INT7327 Regulation of Th 164 0.62 29.67 110.14 96.56
157 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69 96.56
158 INT15481 Positive_regulation of asa 13 0.39 6.12 8.24 96.56
159 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24 96.52
160 INT4450 Negative_regulation of KNCN 2 0.07 0.46 0.35 96.52
161 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15 96.48
162 INT192082 Localization of BMPR2 1 0.32 0.55 0.15 96.48
163 INT1473 Localization of Gcg 95 0.80 17.35 30.31 96.44
164 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 96.44
165 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.44
166 INT24907 Gene_expression of PAPPA 42 0.75 28.32 6.63 96.44
167 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 96.42
168 INT9347 Localization of Il1b 58 0.81 26.13 31.53 96.32
169 INT110 Regulation of Adrb3 33 0.60 8.09 13.84 96.28
170 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37 96.28
171 INT50061 Negative_regulation of Edn3 4 0.58 0.77 0.65 96.28
172 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 96.24
173 INT60478 Gene_expression of UGT1A6 26 0.78 1.57 5.98 96.20
174 INT59 Regulation of Adrb1 25 0.42 8.32 9.78 96.04
175 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 96.04
176 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 96.00
177 INT22272 Negative_regulation of HTR2A 28 0.57 7.62 13.87 96.00
178 INT39986 Regulation of Agtr2 13 0.45 10.39 3.55 96.00
179 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 95.92
180 INT20378 Localization of Hand1 53 0.71 41.96 13.31 95.88
181 INT285510 Regulation of Localization of Hand1 6 0.14 6.13 1.61 95.88
182 INT1114 Localization of Ins1 748 0.80 192.95 165.48 95.84
183 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 95.84
184 INT349671 Phosphorylation of PYCARD 1 0.33 0 0.35 95.56
185 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 95.36
186 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35 95.36
187 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 95.36
188 INT83607 Positive_regulation of CSAD 13 0.59 14.24 8.07 95.24
189 INT28174 Negative_regulation of CCHCR1 8 0.57 4.41 1.92 95.20
190 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 95.20
191 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 94.92
192 INT39369 Binding of NARFL 14 0.29 16.7 0.93 94.92
193 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42 94.92
194 INT126322 Negative_regulation of TGFBI 4 0.41 2.12 1.63 94.92
195 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39 94.80
196 INT171150 Negative_regulation of Binding of Ace 2 0.17 2.67 0.44 94.80
197 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42 94.80
198 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41 94.32
199 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 94.24
200 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 94.12
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