P:biopsychosocial

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Pain Term
Category Other
Synonyms None
Pain Specific No
Documents 682
Hot Single Events 23
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for biopsychosocial. They are ordered first by their pain relevance and then by number of times they were reported for biopsychosocial. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT267812 Binding of ATF7IP and RLS 1 0.35 2.01 0.21 50.00
2 INT327562 Binding of MCS and AKR1B10 1 0.00 0.5 0.41 29.80
3 INT304190 Binding of HP and ZFP91 1 0.00 2.74 0.03 6.32
4 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
5 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
6 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
7 INT304189 Binding of HP and ADHD1 1 0.02 2.59 0.07 5.00
8 INT198620 CRH Negative_regulation of GH1 1 0.05 0.47 0.05 5.00
9 INT198619 CRH Negative_regulation of TRH 1 0.18 0.47 0.05 5.00
10 INT198618 CRH Negative_regulation of Localization of SST 1 0.07 0.53 0.05 5.00
11 INT304191 Binding of SNRPD1 and ADHD1 1 0.01 0.99 0 5.00
12 INT262413 Binding of EPHB1 and ADHD1 1 0.17 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for biopsychosocial. They are ordered first by their pain relevance and then by number of times they were reported in biopsychosocial. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT85227 Positive_regulation of Gene_expression of JBS 1 0.30 0.45 0.5 99.76
2 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 99.40
3 INT85226 Gene_expression of JBS 2 0.38 0.94 0.97 98.94
4 INT75742 Binding of RLS 86 0.42 95.27 19.04 95.32
5 INT133038 Binding of DNMT3B 26 0.40 5.97 2.83 93.48
6 INT161856 Regulation of Mos 1 0.21 0.52 0.43 93.12
7 INT161855 Regulation of Regulation of Mos 1 0.21 0.26 0.22 93.12
8 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 89.32
9 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42 89.32
10 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 88.48
11 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 87.56
12 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 87.56
13 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 87.56
14 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 87.56
15 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 87.16
16 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 87.16
17 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 87.16
18 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 87.16
19 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 87.16
20 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 83.60
21 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 83.04
22 INT80926 Regulation of HTR4 4 0.60 1.85 2.36 82.64
23 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 82.40
24 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 77.84
25 INT54602 Regulation of MCS 22 0.24 10.41 5.75 77.76
26 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31 77.68
27 INT33517 Gene_expression of TSHR 20 0.71 14.65 1.45 76.88
28 INT263074 Positive_regulation of TAPVR1 2 0.43 2.73 1.97 76.80
29 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 76.00
30 INT97383 Positive_regulation of Positive_regulation of NOSTRIN 2 0.08 1.53 1.05 76.00
31 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 75.36
32 INT661 Gene_expression of REN 100 0.78 48.21 11.36 75.36
33 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 72.80
34 INT194979 Positive_regulation of DFNA5 1 0.06 0 0.04 71.44
35 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 70.84
36 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 69.68
37 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 68.84
38 INT181588 Regulation of OPN1SW 14 0.39 8.32 3.59 68.16
39 INT194986 Positive_regulation of IMPACT 4 0.33 0.63 0.18 64.24
40 INT65480 Gene_expression of Pts 15 0.66 7.53 6.46 64.08
41 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 63.84
42 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 63.84
43 INT6063 Positive_regulation of Bche 17 0.66 6.07 3.08 62.96
44 INT194987 Localization of INPP5J 1 0.44 0.07 0.03 58.44
45 INT11107 Binding of Lbp 12 0.42 4.42 3.41 58.20
46 INT154285 Positive_regulation of F8a1 1 0.00 0.08 0.1 56.48
47 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 50.36
48 INT1026 Binding of Lbp 207 0.48 150.96 119.16 50.00
49 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 50.00
50 INT9664 Binding of LBP 127 0.48 94.9 63.42 50.00
51 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 50.00
52 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71 50.00
53 INT14690 Localization of CSF2 124 0.80 85.17 27.26 50.00
54 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 50.00
55 INT142735 Regulation of RLS 33 0.53 45.83 11.35 50.00
56 INT14301 Binding of CSF2 82 0.48 67.95 8.98 50.00
57 INT125242 Localization of RLS 15 0.64 15.87 4.99 50.00
58 INT23366 Positive_regulation of Tshb 10 0.50 4.11 1.79 50.00
59 INT307060 Negative_regulation of AKTIP 6 0.01 2.79 0.08 50.00
60 INT132477 Negative_regulation of TSHB 5 0.45 3.24 0.05 50.00
61 INT346713 Positive_regulation of AKTIP 1 0.01 0.31 0.05 50.00
62 INT47375 Localization of Pts 4 0.59 2.7 0.44 49.68
63 INT351894 Negative_regulation of SHC1 1 0.12 0.69 0.14 45.52
64 INT225061 Regulation of CTTN 1 0.07 1.15 0.55 43.48
65 INT20628 Positive_regulation of EIF3K 2 0.07 0.23 0.15 42.60
66 INT62510 Positive_regulation of MCS 32 0.60 11.79 5.45 35.16
67 INT140978 Gene_expression of Impact 8 0.18 2.4 0.17 34.24
68 INT327565 Binding of AKR1B10 1 0.03 1.47 1.48 33.44
69 INT145520 Positive_regulation of Dss1 16 0.39 14.04 3.38 33.36
70 INT52980 Positive_regulation of Dlat 20 0.37 5.14 4.06 32.56
71 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7 30.24
72 INT162177 Binding of EBM 12 0.32 3.34 0.27 30.08
73 INT88868 Binding of MCS 45 0.40 37.43 7.98 29.80
74 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19 29.00
75 INT225060 Gene_expression of ITM2B 2 0.43 5.97 2.33 24.00
76 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 10.52
77 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
78 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
79 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
80 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 5.00
81 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
82 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
83 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 5.00
84 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 5.00
85 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 5.00
86 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
87 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
88 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 5.00
89 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
90 INT1793 Localization of CGA 379 0.81 67.38 114.69 5.00
91 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 5.00
92 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
93 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
94 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
95 INT214 Localization of AVP 370 0.81 208.51 91.09 5.00
96 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
97 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
98 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
99 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
100 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 5.00
101 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
102 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 5.00
103 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 5.00
104 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
105 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 5.00
106 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
107 INT2463 Localization of CCK 101 0.81 37.54 47.59 5.00
108 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 5.00
109 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55 5.00
110 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23 5.00
111 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
112 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
113 INT5793 Binding of CTS 110 0.48 63.91 40.62 5.00
114 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
115 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
116 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 5.00
117 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
118 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
119 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
120 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
121 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 5.00
122 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 5.00
123 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
124 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5 5.00
125 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
126 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 5.00
127 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
128 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
129 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89 5.00
130 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
131 INT96557 Binding of Bdnf 46 0.47 21.74 24.26 5.00
132 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
133 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 5.00
134 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 5.00
135 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 5.00
136 INT1156 Binding of CCK 27 0.48 8.71 20.58 5.00
137 INT11243 Localization of NPY 33 0.78 11.18 19.24 5.00
138 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19 5.00
139 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
140 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 5.00
141 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
142 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 5.00
143 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 5.00
144 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
145 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 5.00
146 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25 5.00
147 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94 5.00
148 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 5.00
149 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 5.00
150 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
151 INT2415 Binding of MAOA 26 0.47 13.26 11.86 5.00
152 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 5.00
153 INT987 Localization of TRH 37 0.78 10.53 11.1 5.00
154 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
155 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 5.00
156 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21 5.00
157 INT102698 Binding of ACCS 54 0.42 66.73 9.06 5.00
158 INT2885 Positive_regulation of Localization of CCK 19 0.70 9.92 8.94 5.00
159 INT684 Binding of AVP 38 0.48 13.9 8.85 5.00
160 INT150867 Regulation of COPD 54 0.48 71.38 8.8 5.00
161 INT32624 Regulation of LBP 15 0.60 11.48 8.71 5.00
162 INT14043 Binding of HP 52 0.30 26.56 7.76 5.00
163 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 5.00
164 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 5.00
165 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 5.00
166 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 5.00
167 INT3915 Gene_expression of SCD 25 0.57 13.94 6 5.00
168 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 5.00
169 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 5.00
170 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 5.00
171 INT134346 Binding of PCS 51 0.37 22.27 5.67 5.00
172 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 5.00
173 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18 5.00
174 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 5.00
175 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
176 INT78719 Binding of Ucp1 8 0.41 8.93 4.5 5.00
177 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
178 INT137239 Gene_expression of CASZ1 8 0.71 4.63 4.19 5.00
179 INT41791 Positive_regulation of NTS 12 0.49 5.69 4.15 5.00
180 INT164220 Gene_expression of OPN1SW 21 0.65 13.7 4.14 5.00
181 INT181589 Binding of OPN1SW 13 0.32 9.47 4.07 5.00
182 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 5.00
183 INT93911 Regulation of COX5A 11 0.60 4.94 4.05 5.00
184 INT106805 Localization of ACCS 15 0.53 15.22 3.98 5.00
185 INT68789 Regulation of CFP 17 0.51 4.76 3.98 5.00
186 INT24366 Positive_regulation of Localization of NPY 4 0.50 4.01 3.79 5.00
187 INT181922 Binding of RENBP 16 0.36 13.92 3.71 5.00
188 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 5.00
189 INT210946 Binding of Sqle 3 0.31 2.19 3.62 5.00
190 INT91070 Regulation of GSR 27 0.59 16.64 3.42 5.00
191 INT148892 Binding of HPS1 13 0.37 19.21 3.35 5.00
192 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33 5.00
193 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 5.00
194 INT65916 Gene_expression of LAMB1 13 0.55 3.09 3.06 5.00
195 INT121531 Negative_regulation of DNMT3B 13 0.36 3.46 3.05 5.00
196 INT61714 Binding of FGD1 12 0.35 7.72 2.91 5.00
197 INT47503 Gene_expression of HPS1 12 0.58 7.96 2.7 5.00
198 INT263073 Gene_expression of TAPVR1 6 0.58 4.66 2.61 5.00
199 INT185407 Binding of PER1 13 0.42 9.32 2.6 5.00
200 INT15606 Localization of FSHB 24 0.78 9.16 2.49 5.00
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