P:cingulotomy

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pChart

Pain Term
Category Treatment
Synonyms None
Pain Specific No
Documents 40
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for cingulotomy. They are ordered first by their pain relevance and then by number of times they were reported for cingulotomy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
2 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4 5.00
3 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27 5.00
4 INT282503 Binding of ocd and Dlgap3 1 0.28 1.58 0.03 5.00
5 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0 5.00
6 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0 5.00
7 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for cingulotomy. They are ordered first by their pain relevance and then by number of times they were reported in cingulotomy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.16
2 INT249718 Binding of MCF2L 6 0.16 3.52 2.36 98.64
3 INT169173 Gene_expression of ocd 9 0.50 4.49 1.28 65.20
4 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76 65.20
5 INT143612 Positive_regulation of AIC 13 0.70 2.95 6.15 55.44
6 INT151684 Gene_expression of MCF2L 7 0.54 6.25 3.76 39.80
7 INT316009 Binding of AHSG 1 0.15 0.18 0.32 27.36
8 INT97516 Binding of PYCARD 46 0.36 7.06 7.85 12.24
9 INT94545 Positive_regulation of C7orf49 37 0.69 12.91 11.19 11.60
10 INT131199 Positive_regulation of Positive_regulation of C7orf49 7 0.08 4.98 4.65 11.60
11 INT154229 Gene_expression of ARSD 22 0.57 12.5 6.19 10.96
12 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
13 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
14 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
15 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 5.00
16 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
17 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 5.00
18 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 5.00
19 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
20 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02 5.00
21 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
22 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 5.00
23 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
24 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
25 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31 5.00
26 INT32007 Gene_expression of ECT 56 0.62 18.94 11.13 5.00
27 INT145875 Gene_expression of Grm2 28 0.58 6.81 10.19 5.00
28 INT93490 Gene_expression of GPM6A 14 0.69 3.14 9.08 5.00
29 INT85651 Positive_regulation of ACACA 17 0.67 4.73 8.63 5.00
30 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27 5.00
31 INT69460 Positive_regulation of Grm2 12 0.49 6.54 8.18 5.00
32 INT112104 Binding of Grin2b 21 0.44 6.78 8.16 5.00
33 INT101121 Regulation of Comt 19 0.53 10.66 7.22 5.00
34 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76 5.00
35 INT22205 Gene_expression of CCT6A 7 0.29 0.86 6.63 5.00
36 INT137052 Positive_regulation of PYCARD 30 0.43 4.72 6.17 5.00
37 INT223568 Gene_expression of GYPE 21 0.65 5.83 6.12 5.00
38 INT57721 Localization of CCT6A 2 0.16 3.12 5.88 5.00
39 INT65150 Gene_expression of Drb1 10 0.44 12.97 5.82 5.00
40 INT166765 Localization of PYCARD 21 0.70 3.89 5.66 5.00
41 INT148968 Gene_expression of Gpbar1 29 0.56 11.9 5.66 5.00
42 INT102836 Binding of LRP2 12 0.38 11.27 5.58 5.00
43 INT232663 Positive_regulation of CCT6A 1 0.13 3.08 5.27 5.00
44 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 5.00
45 INT112458 Localization of Selenbp2 4 0.04 1.1 4.74 5.00
46 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44 5.00
47 INT85677 Positive_regulation of Gpbar1 24 0.68 8.41 4.09 5.00
48 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 5.00
49 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06 5.00
50 INT120810 Binding of Dlg4 38 0.41 3.55 4.03 5.00
51 INT269961 Gene_expression of Hoxb8 3 0.69 14.28 3.91 5.00
52 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6 5.00
53 INT9295 Regulation of MAOB 12 0.56 3.32 3.6 5.00
54 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56 5.00
55 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17 5.00
56 INT198076 Gene_expression of Slc1a1 13 0.73 2.41 3.07 5.00
57 INT108501 Binding of ARSD 14 0.32 11.5 2.93 5.00
58 INT162957 Positive_regulation of STON1 5 0.35 4.83 2.77 5.00
59 INT63112 Binding of Hrh1 6 0.17 3.83 2.76 5.00
60 INT316010 Binding of AIC 3 0.42 1.47 2.4 5.00
61 INT69020 Gene_expression of Htr2c 9 0.74 6.09 2.22 5.00
62 INT124051 Regulation of ACACA 4 0.60 1.1 1.98 5.00
63 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97 5.00
64 INT232662 Localization of MS 1 0.03 0.57 1.95 5.00
65 INT232666 Negative_regulation of AK1 1 0.02 2.52 1.88 5.00
66 INT149441 Positive_regulation of MCF2L 5 0.61 3.96 1.82 5.00
67 INT218827 Negative_regulation of Phosphorylation of Gria1 6 0.36 3.61 1.67 5.00
68 INT92774 Gene_expression of PVALB 3 0.37 3.47 1.63 5.00
69 INT77586 Positive_regulation of Gene_expression of HTR1A 6 0.46 3.54 1.51 5.00
70 INT65515 Binding of ocd 7 0.36 6.62 1.48 5.00
71 INT114808 Positive_regulation of Binding of SLC6A3 4 0.50 0.63 1.45 5.00
72 INT118267 Negative_regulation of ARSD 14 0.36 8.27 1.44 5.00
73 INT127670 Positive_regulation of ARSD 8 0.54 1.75 1.33 5.00
74 INT145874 Positive_regulation of Positive_regulation of Grm2 2 0.12 1.24 1.32 5.00
75 INT267652 Negative_regulation of Gene_expression of PYCARD 6 0.37 2.35 1.22 5.00
76 INT232661 Negative_regulation of Gene_expression of GPM6A 1 0.02 0.81 1.2 5.00
77 INT162831 Regulation of ARSD 13 0.35 6.17 1.19 5.00
78 INT232665 Gene_expression of WIPF3 1 0.06 1.85 1.14 5.00
79 INT171433 Gene_expression of AIC 7 0.59 3.06 1.11 5.00
80 INT9551 Regulation of AK1 2 0.03 1.38 1.03 5.00
81 INT151428 Localization of C7orf49 3 0.70 0.39 0.99 5.00
82 INT232664 Regulation of Positive_regulation of AK1 1 0.02 0.91 0.95 5.00
83 INT46369 Positive_regulation of AK1 3 0.09 1.24 0.94 5.00
84 INT92778 Negative_regulation of Gene_expression of PVALB 2 0.24 1.71 0.92 5.00
85 INT282479 Regulation of Protein_catabolism of Comt 2 0.45 1.17 0.85 5.00
86 INT195521 Regulation of Grm2 2 0.07 0.51 0.62 5.00
87 INT267651 Positive_regulation of CTSL1 1 0.09 0.96 0.55 5.00
88 INT282488 Negative_regulation of ocd 1 0.43 2.38 0.49 5.00
89 INT137556 Negative_regulation of Cyp19a1 3 0.35 1.53 0.48 5.00
90 INT316008 Negative_regulation of Positive_regulation of AIC 1 0.37 0.33 0.45 5.00
91 INT244273 Negative_regulation of Gene_expression of ECT 3 0.33 1.41 0.35 5.00
92 INT211023 Positive_regulation of Gene_expression of Htr2c 2 0.45 2.03 0.33 5.00
93 INT282487 Regulation of Negative_regulation of Cyp19a1 1 0.22 0.6 0.27 5.00
94 INT282482 Positive_regulation of ocd 1 0.37 0.95 0.26 5.00
95 INT282483 Regulation of ocd 1 0.33 2.43 0.24 5.00
96 INT282486 Gene_expression of Aaiq4 1 0.01 0.6 0.24 5.00
97 INT269960 Negative_regulation of Hoxb8 2 0.38 1.03 0.24 5.00
98 INT282485 Positive_regulation of Gene_expression of Gpbar1 1 0.17 0.94 0.24 5.00
99 INT282473 Gene_expression of Dlgap3 1 0.71 3.11 0.23 5.00
100 INT243500 Protein_catabolism of ARSD 1 0.69 0.67 0.17 5.00
101 INT243501 Positive_regulation of Positive_regulation of ACACA 1 0.01 0.09 0.16 5.00
102 INT154230 Regulation of Gene_expression of ARSD 2 0.35 1.01 0.14 5.00
103 INT198075 Binding of Slc1a1 2 0.35 1.02 0.14 5.00
104 INT282477 Gene_expression of D1Sta7 1 0.01 0.67 0.09 5.00
105 INT180484 Negative_regulation of SLITRK1 2 0.18 1.83 0.09 5.00
106 INT282484 Localization of Dlgap3 1 0.74 0.66 0.07 5.00
107 INT282478 Positive_regulation of Dlgap3 1 0.46 0.82 0.03 5.00
108 INT282475 Negative_regulation of Dlgap3 1 0.39 0.7 0 5.00
109 INT282476 Binding of Grik2 1 0.31 0.61 0 5.00
110 INT282480 Binding of Grik3 1 0.39 0.61 0 5.00
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