P:diclofenac

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 2987
Hot Single Events 200
Hot Interactions 60

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for diclofenac. They are ordered first by their pain relevance and then by number of times they were reported for diclofenac. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8 100.00
2 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76 100.00
3 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51 100.00
4 INT117483 SFXN3 Negative_regulation of THRB 1 0.15 0.15 0.51 100.00
5 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55 100.00
6 INT22820 ADRA1D Regulation of ELANE 1 0.21 0 0.15 100.00
7 INT138862 ABCC2 Negative_regulation of ABCC4 1 0.63 0.24 0.9 100.00
8 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37 99.58
9 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47 99.56
10 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89 99.44
11 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4 99.30
12 INT155220 ABCG2 Positive_regulation of Abcc2 1 0.23 0.54 0.76 99.24
13 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81 99.02
14 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 98.72
15 INT68557 ZNF697 Negative_regulation of PTGS1 1 0.02 0.59 0.33 98.36
16 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 98.20
17 INT121852 CASP8 Positive_regulation of Localization of CYCS 1 0.32 0.48 0.4 98.12
18 INT121849 CASP8 Positive_regulation of CYCS 1 0.35 0.48 0.4 98.12
19 INT121850 CASP8 Positive_regulation of Protein_catabolism of BID 2 0.21 1.81 0.43 98.12
20 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8 98.00
21 INT121856 BID Regulation of ROS1 1 0.05 0.52 0.41 97.76
22 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41 97.76
23 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41 97.76
24 INT121855 CASP8 Regulation of ROS1 1 0.05 0.52 0.41 97.76
25 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41 97.76
26 INT112661 Cpox Positive_regulation of Localization of TNF 1 0.01 0.79 0.52 96.88
27 INT118568 Binding of Ddit3 and Atf6 1 0.33 0.85 0.66 96.80
28 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74 96.64
29 INT112659 Cpox Positive_regulation of Gene_expression of TNF 1 0.01 0.79 0.52 95.92
30 INT65007 DAK Negative_regulation of CTSA 1 0.03 0.35 0.48 95.92
31 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14 95.52
32 INT65006 DAK Negative_regulation of ELANE 1 0.05 0.35 0.47 95.36
33 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36 94.24
34 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36 93.88
35 INT66129 Binding of Tia1 and Olfr927-ps1 1 0.16 0.16 0.56 92.84
36 INT161995 Binding of Ctu2 and Fbxo23 1 0.06 0.33 1.28 92.32
37 INT161993 Negative_regulation of Binding of Ctu2 and Fbxo23 1 0.07 0.16 0.66 92.32
38 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6 92.00
39 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23 91.80
40 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23 91.80
41 INT122315 Negative_regulation of Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56 91.20
42 INT122313 Nfkb1 Regulation of Gene_expression of Cpox 1 0.00 0.51 0.57 90.76
43 INT122314 Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56 90.76
44 INT331924 Binding of Arg1 and Actvty1 1 0.03 1.11 0.05 90.60
45 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44 90.36
46 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 90.08
47 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92 89.88
48 INT105917 Binding of SLC22A6 and SLC22A8 2 0.31 0.34 1.67 89.60
49 INT331927 Ptger2 Positive_regulation of Arg1 1 0.06 1.8 0.42 88.48
50 INT331925 Ptger2 Positive_regulation of Actvty1 1 0.01 0.77 0.38 88.48
51 INT114735 Mtx1 Regulation of Ptgs1 1 0.01 0.31 0.69 86.80
52 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27 86.16
53 INT159903 Binding of CYP2C8 and CYP2C9 1 0.42 0.22 0.35 85.36
54 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18 84.72
55 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22 84.48
56 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8 83.52
57 INT59189 Negative_regulation of GBE1 Negative_regulation of ALOX5 1 0.00 0.33 0.31 83.52
58 INT331923 Actvty1 Positive_regulation of Ptger2 1 0.01 0.99 0.04 83.44
59 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69 82.40
60 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3 81.92
61 INT156261 Negative_regulation of Binding of Oxt and Ca2 1 0.16 0.12 0.3 75.76
62 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26 75.60
63 INT97197 MSD Negative_regulation of SGCG 1 0.02 0.36 0.32 75.52
64 INT97198 MSD Positive_regulation of MSD Negative_regulation of SGCG 1 0.00 0.36 0.32 75.52
65 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 75.40
66 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5 75.40
67 INT156262 Binding of Oxt and Ca2 1 0.14 0.12 0.3 75.28
68 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89 75.16
69 INT161996 Binding of Gabbr2 and Fbxo23 1 0.29 0.15 0.33 75.00
70 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26 74.48
71 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2 73.80
72 INT312726 AASS Positive_regulation of FGD1 1 0.02 0.08 0.24 73.52
73 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54 69.44
74 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62 67.56
75 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61 67.00
76 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05 64.24
77 INT71940 VN1R106P Regulation of ZNF697 Negative_regulation of PTGS2 1 0.00 0.07 0.54 63.92
78 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54 63.92
79 INT71945 ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.53 63.92
80 INT207375 Negative_regulation of CPOX Negative_regulation of Gene_expression of Chol1 1 0.10 0.37 0.17 60.12
81 INT347301 AREG Positive_regulation of CCL16 1 0.01 0.86 0.16 59.60
82 INT69120 MOCS1 Regulation of PTGS2 1 0.00 0.39 0.26 58.48
83 INT12702 Regulation of Binding of FPR1 and GUSB 1 0.43 0.18 0.44 57.16
84 INT12703 Binding of FPR1 and GUSB 1 0.36 0.18 0.44 57.16
85 INT334379 Ros1 Regulation of Cat 1 0.04 0.08 0.21 51.00
86 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58 50.00
87 INT141576 Slc6a14 Positive_regulation of Gene_expression of Tnf 1 0.05 0.07 0 50.00
88 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65 46.56
89 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64 46.56
90 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64 46.08
91 INT347291 Binding of AKT1 and CCL16 1 0.06 0.99 0.04 44.92
92 INT347299 Binding of AKT1 and ITK 1 0.04 0.99 0.04 44.92
93 INT217760 Il1f5 Positive_regulation of Gene_expression of Cpox 1 0.00 0.27 0.47 43.36
94 INT217759 Il1f5 Positive_regulation of Cpox 1 0.00 0.27 0.47 43.36
95 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62 41.68
96 INT347300 Binding of ITK and CCL16 1 0.02 0.97 0.04 41.40
97 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 39.56
98 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61 37.92
99 INT88567 COL2A1 Positive_regulation of A1cf 1 0.09 0.36 0 37.20
100 INT63459 Binding of Calca and Phax 1 0.00 0.12 0.49 36.28
101 INT271780 Zfp560 Negative_regulation of Cpox 1 0.00 0.62 0.86 34.64
102 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0 33.04
103 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0 32.48
104 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55 28.80
105 INT112660 TNF Regulation of Tnf 1 0.02 0.94 0.08 26.16
106 INT224678 Binding of Mmp14 and Mmp23 1 0.00 0.85 0.69 25.92
107 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 25.20
108 INT63453 Positive_regulation of PTGS1 Positive_regulation of Gene_expression of PLEKHM1 1 0.05 0.09 0.16 25.00
109 INT347290 Positive_regulation of CCL16 Positive_regulation of PIK3CB 1 0.03 0.57 0 22.16
110 INT347303 Positive_regulation of CCL16 Positive_regulation of AKT1 1 0.08 0.57 0 22.16
111 INT224702 Timp2 Positive_regulation of Binding of Mmp14 and Mmp9 1 0.00 0.81 0.65 21.76
112 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65 21.76
113 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65 21.48
114 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64 20.96
115 INT302145 Positive_regulation of AKT1 Positive_regulation of Phosphorylation of BAD 1 0.07 0.9 0 9.68
116 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 7.56
117 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
118 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
119 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
120 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
121 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
122 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
123 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
124 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87 5.00
125 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
126 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
127 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
128 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
129 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 5.00
130 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
131 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 5.00
132 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9 5.00
133 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
134 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
135 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
136 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69 5.00
137 INT167505 Binding of CXCR3 and CXCL11 2 0.26 0.86 0.67 5.00
138 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67 5.00
139 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64 5.00
140 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62 5.00
141 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62 5.00
142 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59 5.00
143 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59 5.00
144 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58 5.00
145 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57 5.00
146 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56 5.00
147 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 5.00
148 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53 5.00
149 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 5.00
150 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 5.00
151 INT224675 S100a4 Positive_regulation of Mmp3 1 0.04 0.94 0.48 5.00
152 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46 5.00
153 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46 5.00
154 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46 5.00
155 INT224674 S100a4 Positive_regulation of Gene_expression of Mmp9 1 0.03 0.85 0.45 5.00
156 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 1 0.04 0.59 0.45 5.00
157 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45 5.00
158 INT224692 S100a4 Positive_regulation of Gene_expression of Mmp1a 1 0.02 0.85 0.45 5.00
159 INT222924 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il12a 1 0.01 0.59 0.45 5.00
160 INT222922 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il1 1 0.01 0.56 0.44 5.00
161 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 5.00
162 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 5.00
163 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 5.00
164 INT209918 Positive_regulation of Nlrp3 Positive_regulation of Localization of Il1 1 0.42 1.06 0.4 5.00
165 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38 5.00
166 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35 5.00
167 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
168 INT224701 Timp3 Negative_regulation of TNF 1 0.01 0.65 0.34 5.00
169 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34 5.00
170 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33 5.00
171 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33 5.00
172 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 5.00
173 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31 5.00
174 INT207355 ZNF398 Regulation of CYP27A1 1 0.00 0 0.31 5.00
175 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
176 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24 5.00
177 INT348364 PROC Negative_regulation of TNF 1 0.01 0.89 0.23 5.00
178 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 5.00
179 INT172083 TNF Regulation of Regulation of IFNA1 1 0.03 0.91 0.22 5.00
180 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 5.00
181 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 5.00
182 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21 5.00
183 INT348363 PCTP Positive_regulation of PROC 1 0.01 0.41 0.2 5.00
184 INT348372 Binding of PROC and Stard10 1 0.01 0.41 0.2 5.00
185 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2 5.00
186 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2 5.00
187 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19 5.00
188 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
189 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
190 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 5.00
191 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18 5.00
192 INT207339 TBXA2R Negative_regulation of Negative_regulation of CYP27A1 1 0.01 0 0.17 5.00
193 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17 5.00
194 INT207348 TBXA2R Negative_regulation of CPOX 1 0.03 0 0.17 5.00
195 INT207354 TBXA2R Regulation of Gene_expression of CYP27A1 1 0.01 0 0.17 5.00
196 INT207342 PTGDS Negative_regulation of Gene_expression of CYP27A1 1 0.02 0 0.17 5.00
197 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17 5.00
198 INT207351 ZNF398 Negative_regulation of CYP27A1 1 0.00 0 0.17 5.00
199 INT207340 PTGER2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0.17 5.00
200 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for diclofenac. They are ordered first by their pain relevance and then by number of times they were reported in diclofenac. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72 100.00
2 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
3 INT3765 Positive_regulation of Actvty1 8 0.06 23.53 7.37 100.00
4 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 100.00
5 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13 100.00
6 INT51458 Negative_regulation of Gene_expression of Selp 29 0.57 12.64 8.1 100.00
7 INT109334 Regulation of SOD2 13 0.60 7.48 2.14 100.00
8 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 100.00
9 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 100.00
10 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 100.00
11 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 100.00
12 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 100.00
13 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
14 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
15 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 100.00
16 INT23257 Regulation of CRP 127 0.62 100.05 21.87 100.00
17 INT340843 Binding of Cd24a 1 0.02 0.24 0.8 100.00
18 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
19 INT65630 Regulation of Kcna5 11 0.62 6.61 7.22 100.00
20 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 100.00
21 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53 100.00
22 INT67612 Binding of PPARG 38 0.48 22.67 8.94 100.00
23 INT67423 Regulation of Gene_expression of Selp 16 0.60 7.4 3.68 100.00
24 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 100.00
25 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2 100.00
26 INT114708 Regulation of Olr1 5 0.40 1.55 1.86 100.00
27 INT73902 Regulation of Gene_expression of IL1RN 6 0.61 4.59 6.14 100.00
28 INT155218 Binding of ABCB6 18 0.35 13.93 2.25 100.00
29 INT155236 Negative_regulation of TXN 5 0.53 0.66 0.46 100.00
30 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35 100.00
31 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58 100.00
32 INT71948 Negative_regulation of VN1R106P 1 0.01 0.79 4.43 100.00
33 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71 100.00
34 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77 100.00
35 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6 100.00
36 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 100.00
37 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96 100.00
38 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58 100.00
39 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
40 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53 100.00
41 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77 100.00
42 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
43 INT4486 Regulation of TSHB 5 0.28 0.99 1.42 100.00
44 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
45 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 100.00
46 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87 100.00
47 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 100.00
48 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 100.00
49 INT51686 Regulation of Gene_expression of LTB4R 10 0.26 5.02 2.99 100.00
50 INT51683 Regulation of Gene_expression of PTAFR 11 0.60 5.06 2.59 100.00
51 INT51684 Regulation of LTB4R 6 0.36 3.04 2.15 100.00
52 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 100.00
53 INT62980 Protein_catabolism of Ptgs1 3 0.59 0.93 0.97 100.00
54 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82 100.00
55 INT44122 Positive_regulation of AMPD1 4 0.44 1.88 0.92 100.00
56 INT47999 Positive_regulation of Zfp697 1 0.00 0.14 0.45 100.00
57 INT65502 Regulation of App 77 0.62 52.05 19.44 100.00
58 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41 100.00
59 INT51681 Regulation of Localization of LTB4R 1 0.16 0.17 0.6 100.00
60 INT16345 Regulation of Gene_expression of CASP4 3 0.26 0.42 1.08 100.00
61 INT113912 Positive_regulation of P4HTM 1 0.09 0.17 0.17 100.00
62 INT113911 Negative_regulation of P4HTM 1 0.08 0.17 0.17 100.00
63 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.98
64 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03 99.98
65 INT132568 Negative_regulation of Positive_regulation of RFFL 1 0.33 4.86 2.09 99.98
66 INT234 Binding of Alb 151 0.48 52.34 32.97 99.98
67 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41 99.98
68 INT116216 Negative_regulation of Gene_expression of Kcna5 4 0.43 3.11 2.64 99.98
69 INT22482 Negative_regulation of Gene_expression of CADM1 6 0.49 3.2 1.8 99.98
70 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 99.98
71 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12 99.98
72 INT91158 Regulation of Ros1 26 0.25 17 4.23 99.98
73 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 99.98
74 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02 99.98
75 INT50290 Binding of Cpox 29 0.27 17.19 8.01 99.98
76 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3 99.98
77 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85 99.98
78 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 99.98
79 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01 99.98
80 INT62828 Negative_regulation of Gene_expression of ESAM 3 0.57 0.4 0.34 99.98
81 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 99.98
82 INT123741 Negative_regulation of EIF4G3 1 0.17 0.15 0.6 99.98
83 INT93401 Positive_regulation of Protein_catabolism of Nfkbia 11 0.46 3.89 2.7 99.98
84 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 99.98
85 INT172808 Positive_regulation of Positive_regulation of ROS1 35 0.40 31.39 2.27 99.98
86 INT319182 Positive_regulation of Negative_regulation of SOD2 1 0.46 0.95 0.17 99.98
87 INT86901 Negative_regulation of Mia 3 0.37 2.11 1.67 99.98
88 INT105021 Binding of GOPC 187 0.40 60.39 20.38 99.98
89 INT94048 Positive_regulation of Positive_regulation of Arg1 2 0.44 1.91 0.32 99.98
90 INT22765 Negative_regulation of Localization of Ptger2 14 0.34 3 5.75 99.98
91 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 99.96
92 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.96
93 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 99.96
94 INT93288 Localization of Slc25a10 1 0.61 0.74 0.46 99.96
95 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56 99.96
96 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 99.94
97 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.92
98 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.92
99 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.92
100 INT102654 Positive_regulation of Pln 10 0.48 3.53 4.19 99.88
101 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6 99.88
102 INT60032 Negative_regulation of Pla2g2a 29 0.58 12.42 5.75 99.88
103 INT148985 Positive_regulation of Positive_regulation of BID 1 0.53 0.84 0.48 99.88
104 INT62823 Negative_regulation of Positive_regulation of VCAM1 2 0.43 0.48 1.08 99.88
105 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39 99.88
106 INT62831 Negative_regulation of Positive_regulation of SELE 3 0.36 1.63 0.69 99.88
107 INT109333 Negative_regulation of Gene_expression of SOD2 2 0.42 0.71 0.24 99.88
108 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 99.86
109 INT9643 Negative_regulation of Actvty1 7 0.07 5.54 3.31 99.84
110 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.84
111 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 99.84
112 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.84
113 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 99.84
114 INT65627 Negative_regulation of Kcna5 19 0.59 7.82 10.79 99.84
115 INT94050 Negative_regulation of Arg1 6 0.39 6.07 2.06 99.84
116 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88 99.84
117 INT6148 Gene_expression of Nrtim1 34 0.42 10.17 12.27 99.84
118 INT80559 Negative_regulation of Slc25a5 2 0.32 0.15 0.45 99.84
119 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52 99.84
120 INT162614 Positive_regulation of Mia 1 0.44 1.82 2.25 99.84
121 INT6544 Negative_regulation of Localization of Cck 67 0.59 8.05 47.23 99.84
122 INT34085 Negative_regulation of Gene_expression of PGE 16 0.35 4.9 3.76 99.84
123 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23 99.84
124 INT161991 Regulation of Binding of Fbxo23 1 0.20 0.14 0.59 99.84
125 INT78665 Gene_expression of Irgm1 12 0.65 3.17 1.83 99.84
126 INT20673 Binding of CDS1 18 0.31 1.96 5.72 99.82
127 INT22764 Localization of Ptger2 81 0.64 24.38 26.77 99.82
128 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37 99.80
129 INT5069 Negative_regulation of Mthfs 69 0.57 22.54 31.36 99.80
130 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 99.80
131 INT3768 Negative_regulation of ANPEP 16 0.59 4.96 5.52 99.80
132 INT130814 Binding of ANPEP 8 0.48 4.83 1.05 99.80
133 INT62825 Positive_regulation of Gene_expression of ESAM 2 0.40 0.81 0.53 99.80
134 INT62820 Gene_expression of ESAM 8 0.76 3.2 1.41 99.80
135 INT33781 Binding of Pebp1 11 0.44 1.76 6.61 99.80
136 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06 99.80
137 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 99.80
138 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 99.78
139 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07 99.78
140 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.78
141 INT104928 Positive_regulation of BID 10 0.67 6.9 3.41 99.78
142 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 99.78
143 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 99.78
144 INT100893 Positive_regulation of ABCC3 8 0.64 4.66 3.65 99.76
145 INT326696 Regulation of Cd24a 2 0.44 0 0.48 99.76
146 INT6891 Binding of TTR 72 0.48 22.81 6.51 99.76
147 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94 99.76
148 INT53388 Negative_regulation of Cyp2c11 18 0.53 2.66 3.11 99.74
149 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 99.74
150 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62 99.74
151 INT131619 Positive_regulation of Positive_regulation of Dgat1 1 0.13 0.41 0.21 99.74
152 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.72
153 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01 99.72
154 INT141166 Positive_regulation of Gene_expression of Ddit3 15 0.56 10.32 1.92 99.72
155 INT61804 Negative_regulation of Positive_regulation of Dpp4 1 0.37 0.24 0.42 99.72
156 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 99.72
157 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.70
158 INT40165 Binding of Fbxo23 7 0.30 1.18 3.26 99.70
159 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 99.70
160 INT73903 Positive_regulation of Transcription of IL1RN 2 0.69 1.15 0.87 99.70
161 INT312731 Negative_regulation of UGT2B15 1 0.36 0.38 0.94 99.70
162 INT312739 Negative_regulation of UGT2B17 1 0.59 0.22 0.5 99.70
163 INT76759 Positive_regulation of RFFL 31 0.35 29.15 9.9 99.68
164 INT76758 Positive_regulation of Positive_regulation of RFFL 6 0.35 6.29 3.34 99.68
165 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 99.68
166 INT113961 Regulation of PPT1 6 0.26 3.87 6.09 99.68
167 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 99.68
168 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 99.66
169 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73 99.66
170 INT72564 Localization of Il10 41 0.78 28.62 17.6 99.66
171 INT38303 Binding of Gpt 21 0.47 15.84 3.43 99.66
172 INT230018 Binding of Slc17a5 2 0.21 0.86 0.74 99.66
173 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.64
174 INT5966 Localization of Il1a 50 0.78 22.91 26.54 99.64
175 INT7499 Negative_regulation of Positive_regulation of Sst 9 0.59 0.42 6.9 99.64
176 INT10100 Binding of ELANE 22 0.47 15.32 5.19 99.62
177 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.62
178 INT27964 Negative_regulation of CBR1 12 0.58 5.48 3.74 99.62
179 INT53028 Negative_regulation of CYCS 6 0.57 2.65 1.11 99.62
180 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 99.60
181 INT340845 Regulation of Baat 1 0.08 0 0.47 99.60
182 INT102655 Positive_regulation of Positive_regulation of Ighm 2 0.32 0.74 0.67 99.60
183 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38 99.60
184 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99 99.60
185 INT16344 Gene_expression of CASP4 11 0.74 4.64 6.75 99.60
186 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.58
187 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 99.58
188 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.58
189 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 99.58
190 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.56
191 INT125447 Positive_regulation of CLDN4 14 0.70 4.71 4.45 99.56
192 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 99.56
193 INT173116 Regulation of VCAM1 14 0.33 11.85 1.92 99.56
194 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 99.54
195 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 99.54
196 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 99.54
197 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 99.54
198 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 99.54
199 INT25464 Binding of SAA1 11 0.42 6.89 3.72 99.54
200 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 99.54
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