P:drug abuse

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pChart

Pain Term
Category Other
Synonyms Substance Abuse, Unhealthy Substance Use
Pain Specific No
Documents 3261
Hot Single Events 200
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for drug abuse. They are ordered first by their pain relevance and then by number of times they were reported for drug abuse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26 95.92
2 INT253637 TNF Regulation of Transcription of HIVEP1 1 0.07 1.72 0.26 92.40
3 INT296786 Gopc Regulation of Positive_regulation of Il1 1 0.02 1.37 0.77 89.44
4 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77 89.44
5 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17 89.36
6 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77 89.04
7 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77 89.04
8 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76 89.04
9 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31 88.48
10 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59 86.40
11 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82 86.12
12 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7 82.60
13 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7 82.20
14 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7 82.20
15 INT164458 Negative_regulation of Ngf Positive_regulation of NTRK1 1 0.14 0.57 0.58 81.68
16 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 81.12
17 INT164457 Ngf Positive_regulation of NTRK1 1 0.15 0.57 0.58 80.72
18 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04 80.00
19 INT217075 Binding of Acsm3 and Slc26a4 1 0.04 2.11 0.04 74.84
20 INT353848 Binding of SCLY and Ubash3a 1 0.30 0.47 0.04 74.48
21 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55 62.56
22 INT296291 Prkaca Regulation of Localization of Calm3 1 0.09 0.62 0.55 62.56
23 INT296273 Prkaca Regulation of Localization of Camk4 1 0.16 0.62 0.55 62.56
24 INT296302 Camk4 Regulation of Localization of Calm3 1 0.15 0.31 0.28 62.24
25 INT296287 Camk4 Regulation of Positive_regulation of Creb1 1 0.27 0.31 0.27 62.24
26 INT296284 Calm3 Regulation of Positive_regulation of Creb1 1 0.09 0.31 0.28 61.96
27 INT296281 Calm3 Regulation of Localization of Camk4 1 0.13 0.31 0.28 61.96
28 INT280451 IER5 Positive_regulation of Phc1 1 0.00 0.56 0.09 58.80
29 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43 52.08
30 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 51.84
31 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41 50.84
32 INT264835 Binding of Creb1 and Tpr 1 0.01 0.05 0.06 50.40
33 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 50.00
34 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 50.00
35 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06 49.56
36 INT223558 Dpcr1 Regulation of Cms1 1 0.00 0.79 0.51 49.44
37 INT210898 IGHD1-14 Regulation of SELE 1 0.22 1.51 0 49.44
38 INT296276 Binding of Preb and Kcnip3 1 0.02 0.06 0.16 44.04
39 INT296294 Binding of Kcnip3 and Dre 1 0.13 0.06 0.16 44.04
40 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 43.80
41 INT223556 Churc1 Regulation of Cnr2 1 0.00 0.8 0.54 42.00
42 INT78030 Binding of VEGFC and FCAMR 1 0.01 0.31 0.55 41.80
43 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 39.00
44 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68 32.28
45 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16 23.68
46 INT209130 Binding of Riok3 and Sugt1 1 0.00 0.44 0.4 23.68
47 INT209133 Binding of Bcl2a1a and Riok3 1 0.00 0.44 0.4 23.68
48 INT264839 Positive_regulation of Binding of Eno2 and Tpr 1 0.00 0.17 0.1 21.56
49 INT264838 Binding of Eno2 and Spp1 1 0.00 0.17 0.1 21.56
50 INT264836 Binding of Eno2 and Tpr 1 0.00 0.17 0.1 21.56
51 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08 21.28
52 INT290543 Binding of Crh and Pdyn 1 0.25 1.04 0.43 16.40
53 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 14.16
54 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 13.92
55 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2 13.80
56 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 13.52
57 INT202573 Binding of DIO2 and DRD4 1 0.07 0.09 0.03 8.68
58 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6 5.00
59 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
60 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 5.00
61 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
62 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 5.00
63 INT273120 NOVA2 Regulation of Gene_expression of MET 1 0.23 1.17 2.11 5.00
64 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01 5.00
65 INT189999 Binding of Vta1 and Cfp 2 0.08 1.25 1.97 5.00
66 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78 5.00
67 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71 5.00
68 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
69 INT245347 Binding of Penk and Vta1 1 0.05 0.14 1.53 5.00
70 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52 5.00
71 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51 5.00
72 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36 5.00
73 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 5.00
74 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26 5.00
75 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24 5.00
76 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 5.00
77 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 5.00
78 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 5.00
79 INT218840 Cysltr1 Positive_regulation of Ltp 2 0.02 1.04 1.06 5.00
80 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 5.00
81 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01 5.00
82 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01 5.00
83 INT245349 Binding of Abat and Gpr156 1 0.02 0.26 1 5.00
84 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
85 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96 5.00
86 INT296283 Kcnip3 Regulation of Positive_regulation of Cysltr1 1 0.01 0.85 0.94 5.00
87 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94 5.00
88 INT296278 Insrr Positive_regulation of Cysltr1 1 0.00 0.99 0.92 5.00
89 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
90 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83 5.00
91 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83 5.00
92 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8 5.00
93 INT296299 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Rbm39 1 0.00 0.59 0.79 5.00
94 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78 5.00
95 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78 5.00
96 INT296297 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Car2 1 0.01 0.59 0.77 5.00
97 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75 5.00
98 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75 5.00
99 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73 5.00
100 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72 5.00
101 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72 5.00
102 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 5.00
103 INT290553 Positive_regulation of Oprk1 Positive_regulation of Crh 1 0.33 0.39 0.72 5.00
104 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72 5.00
105 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72 5.00
106 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72 5.00
107 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72 5.00
108 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72 5.00
109 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71 5.00
110 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71 5.00
111 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71 5.00
112 INT290554 Pdyn Positive_regulation of Gpr3 Positive_regulation of Phosphorylation of Oprk1 1 0.17 0.47 0.7 5.00
113 INT290547 Pdyn Positive_regulation of Gpr3 1 0.21 0.42 0.7 5.00
114 INT290539 Positive_regulation of Pdyn Positive_regulation of Gpr3 1 0.21 0.42 0.7 5.00
115 INT290541 Gpr3 Positive_regulation of Phosphorylation of Oprk1 1 0.18 0.45 0.69 5.00
116 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65 5.00
117 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65 5.00
118 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65 5.00
119 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65 5.00
120 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65 5.00
121 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64 5.00
122 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64 5.00
123 INT233669 gr Positive_regulation of Transcription of Nfkbia 1 0.26 0.33 0.64 5.00
124 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64 5.00
125 INT233671 gr Positive_regulation of Transcription of Tsc22d3 1 0.44 0.33 0.64 5.00
126 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 5.00
127 INT209131 Binding of Bcl2a1a and Drd2 1 0.22 0.45 0.62 5.00
128 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
129 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55 5.00
130 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55 5.00
131 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 5.00
132 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
133 INT261497 Binding of PTGDR and LMOD1 1 0.00 0.51 0.54 5.00
134 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 5.00
135 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53 5.00
136 INT290546 Oprk1 Regulation of Positive_regulation of Anxty 1 0.02 0.42 0.52 5.00
137 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 5.00
138 INT261498 CBS Positive_regulation of DSE 1 0.00 0 0.5 5.00
139 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
140 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46 5.00
141 INT233668 Cebpd Negative_regulation of Cebpg 1 0.43 0.66 0.46 5.00
142 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45 5.00
143 INT317427 IFN1@ Positive_regulation of ISYNA1 1 0.12 0.49 0.45 5.00
144 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 5.00
145 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45 5.00
146 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44 5.00
147 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
148 INT322995 Binding of ABCC1 and SSD 1 0.00 0.42 0.41 5.00
149 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4 5.00
150 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4 5.00
151 INT296300 Binding of Grin1 and Kcnip3 1 0.18 0 0.4 5.00
152 INT296301 Binding of Grin2a and Kcnip3 1 0.27 0 0.4 5.00
153 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37 5.00
154 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37 5.00
155 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37 5.00
156 INT190003 Binding of MVD and Slc6a3 1 0.13 0.19 0.37 5.00
157 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 5.00
158 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36 5.00
159 INT352821 Tph2 Regulation of Tst 1 0.31 0.46 0.36 5.00
160 INT352822 SNRNP70 Regulation of Tst 1 0.34 0.46 0.36 5.00
161 INT273982 Ascc1 Regulation of Localization of Abat 1 0.04 0 0.35 5.00
162 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35 5.00
163 INT261499 CBS Positive_regulation of CNR1 1 0.01 0.48 0.35 5.00
164 INT273983 Abat Regulation of Gene_expression of Ascc1 1 0.07 0 0.34 5.00
165 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33 5.00
166 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33 5.00
167 INT311263 RENBP Regulation of TNF 1 0.01 1.59 0.33 5.00
168 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32 5.00
169 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
170 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31 5.00
171 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
172 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31 5.00
173 INT214371 Amph Positive_regulation of Ubqln1 1 0.01 0 0.3 5.00
174 INT290552 Crh Positive_regulation of Positive_regulation of Pdyn 1 0.38 0.23 0.3 5.00
175 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3 5.00
176 INT214373 Negative_regulation of Amph Positive_regulation of Ubqln1 1 0.01 0 0.3 5.00
177 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3 5.00
178 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29 5.00
179 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 5.00
180 INT286703 Mapk1 Positive_regulation of Phosphorylation of Hist1h3f 1 0.22 0.18 0.29 5.00
181 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29 5.00
182 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 5.00
183 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28 5.00
184 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28 5.00
185 INT286709 Mapk1 Positive_regulation of Rps6ka5 Positive_regulation of Rps6ka5 1 0.36 0.18 0.28 5.00
186 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28 5.00
187 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28 5.00
188 INT180194 CRH Positive_regulation of CRHR2 1 0.02 0.24 0.27 5.00
189 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27 5.00
190 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
191 INT180195 CRH Regulation of CRHR2 1 0.01 0.24 0.27 5.00
192 INT310402 Binding of CALM1 and Grin1 1 0.00 0 0.26 5.00
193 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26 5.00
194 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26 5.00
195 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26 5.00
196 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
197 INT214366 Ins1 Regulation of Slc6a3 1 0.11 0.09 0.25 5.00
198 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24 5.00
199 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23 5.00
200 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for drug abuse. They are ordered first by their pain relevance and then by number of times they were reported in drug abuse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT272768 Gene_expression of Nrxn3 5 0.78 4.73 3.31 100.00
2 INT3836 Gene_expression of su 8 0.46 2.8 2.32 100.00
3 INT205755 Binding of su 3 0.04 0.43 0.33 100.00
4 INT310381 Positive_regulation of Gene_expression of Nrxn3 1 0.03 1.19 1 100.00
5 INT210324 Localization of DDOST 3 0.65 1.78 2.4 100.00
6 INT38706 Positive_regulation of Positive_regulation of Alb 4 0.46 3.53 1.11 100.00
7 INT28728 Regulation of Cfp 49 0.46 13.15 21.43 99.98
8 INT118589 Regulation of OFC1 11 0.23 3.35 2.94 99.98
9 INT150698 Regulation of PTPRB 1 0.45 1.52 0.89 99.96
10 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 99.90
11 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 99.90
12 INT100520 Regulation of Grm1 8 0.44 1.3 4.48 99.88
13 INT293904 Regulation of TPH2 4 0.54 2.19 0.65 99.84
14 INT154607 Negative_regulation of DDOST 2 0.37 0.68 0.75 99.84
15 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 99.82
16 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88 99.80
17 INT148894 Binding of Cytl1 2 0.47 0.99 0.77 99.76
18 INT200963 Regulation of UPF1 10 0.01 2.18 2.67 99.68
19 INT200980 Transcription of APOL1 1 0.67 0.84 0.54 99.68
20 INT201021 Transcription of APOL2 1 0.56 0.45 0.38 99.68
21 INT100523 Regulation of GRM5 2 0.26 0.49 1.51 99.68
22 INT154944 Positive_regulation of APOL4 2 0.47 0.36 0.25 99.68
23 INT200948 Regulation of Transcription of APOL2 1 0.37 0.23 0.24 99.68
24 INT200997 Regulation of Transcription of APOL1 1 0.32 0.23 0.24 99.68
25 INT53482 Gene_expression of ITIH4 75 0.77 58.87 26.05 99.66
26 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 99.64
27 INT201004 Negative_regulation of Gene_expression of CALM2 1 0.46 1.58 0.55 99.56
28 INT200990 Gene_expression of CALM2 4 0.61 2.2 0.55 99.56
29 INT155878 Regulation of Gene_expression of Cnr2 4 0.62 7.57 7.25 99.56
30 INT290735 Regulation of Dbt 1 0.17 1.01 0.24 99.56
31 INT226221 Binding of Dusp1 1 0.04 0.92 0.68 99.50
32 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 99.46
33 INT84057 Positive_regulation of Gene_expression of ITIH4 12 0.50 10.5 4.92 99.44
34 INT304999 Localization of OPN1SW 1 0.57 0.36 0.22 99.40
35 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91 99.36
36 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 99.36
37 INT115322 Positive_regulation of Gene_expression of FCGR3A 2 0.37 4.22 0.53 99.36
38 INT42994 Binding of BDNF-AS 21 0.35 14.17 4 99.28
39 INT12484 Binding of Drd2 45 0.48 15.17 24.72 99.28
40 INT15237 Protein_catabolism of Mme 31 0.96 10.26 16.69 99.20
41 INT14114 Binding of Adra2a 30 0.48 4.24 18.53 99.20
42 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89 99.20
43 INT160280 Positive_regulation of ipv 14 0.44 15.73 1.02 99.18
44 INT67899 Localization of Arsi 1 0.60 0.28 0.38 99.16
45 INT304984 Binding of CODA 1 0.18 1.03 0.19 99.16
46 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 99.16
47 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 99.08
48 INT53468 Binding of Acsm3 26 0.24 20.87 2.95 99.06
49 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 99.00
50 INT126906 Positive_regulation of Gene_expression of H2 12 0.21 9.2 1.91 99.00
51 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 99.00
52 INT287528 Gene_expression of WFS1 1 0.75 2.74 1.55 99.00
53 INT287524 Regulation of WFS1 1 0.40 1.34 0.78 99.00
54 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 98.96
55 INT210326 Binding of DDOST 6 0.48 4.27 6.26 98.96
56 INT130117 Regulation of Per1 26 0.53 3.25 7.63 98.96
57 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 98.92
58 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23 98.92
59 INT177906 Gene_expression of Gpr182 9 0.17 1.66 1.61 98.88
60 INT11030 Binding of LPA 70 0.48 40.35 4.81 98.88
61 INT150497 Regulation of Bst1 2 0.24 0.99 0.47 98.88
62 INT201017 Gene_expression of APOL2 1 0.63 1.12 0.47 98.84
63 INT200969 Positive_regulation of Gene_expression of APOL2 1 0.57 0.97 0.43 98.84
64 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 98.80
65 INT168399 Localization of Cnr2 12 0.81 4.37 6.77 98.80
66 INT36428 Binding of Chdh 42 0.47 48.04 26.54 98.76
67 INT105425 Binding of BCAT1 5 0.42 0.78 1.17 98.68
68 INT162 Regulation of Prl 794 0.62 165.01 322.24 98.68
69 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 98.68
70 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9 98.68
71 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 98.64
72 INT138673 Regulation of Gene_expression of TPH2 3 0.62 1.23 1.42 98.64
73 INT50080 Binding of APOE 38 0.45 29.61 2.67 98.64
74 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 98.56
75 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 98.56
76 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 98.52
77 INT22068 Binding of CALCRL 53 0.41 6.14 17.32 98.48
78 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 98.44
79 INT102023 Regulation of Creb1 51 0.62 16.29 16.71 98.40
80 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 98.36
81 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 98.30
82 INT9295 Regulation of MAOB 12 0.56 3.32 3.6 98.26
83 INT217072 Negative_regulation of Acsm3 5 0.29 6.15 1.59 98.24
84 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 98.16
85 INT148456 Gene_expression of LY96 7 0.19 4.35 2.02 98.12
86 INT138671 Gene_expression of TPH2 35 0.78 7.34 6.03 98.08
87 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.08
88 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 98.00
89 INT610 Regulation of PENK 47 0.62 14.17 31.55 97.96
90 INT211051 Gene_expression of FITM1 2 0.28 0.55 0.15 97.90
91 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 97.88
92 INT255702 Positive_regulation of TPH2 4 0.50 1.43 1.37 97.88
93 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 97.84
94 INT196973 Regulation of Gene_expression of Clock 12 0.38 3.58 0.38 97.78
95 INT122924 Binding of ipv 27 0.42 31.81 1.99 97.72
96 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55 97.64
97 INT82983 Transcription of Cartpt 2 0.66 0.17 1.86 97.64
98 INT75497 Regulation of JUN 28 0.61 11.04 7.09 97.58
99 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04 97.58
100 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 97.56
101 INT129665 Regulation of Nrcam 1 0.54 1.13 0.63 97.48
102 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99 97.44
103 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 97.44
104 INT61753 Binding of HBN1 13 0.09 21.66 1.38 97.24
105 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 97.24
106 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38 97.24
107 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 97.20
108 INT182720 Binding of SHE 18 0.26 9.15 2.24 97.20
109 INT90751 Negative_regulation of Gene_expression of Nr4a1 3 0.59 0.75 1.69 97.16
110 INT47708 Gene_expression of Nr4a1 30 0.78 5.12 13.59 97.16
111 INT1893 Localization of Gh 1041 0.79 340.23 256.58 97.12
112 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 97.12
113 INT168396 Transcription of Cnr2 12 0.72 7.69 8.74 97.08
114 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 97.04
115 INT695 Binding of POMC 304 0.48 56.66 126.85 97.04
116 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 97.00
117 INT117245 Gene_expression of CRHR1 3 0.51 3.45 0.73 96.96
118 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3 96.88
119 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 96.84
120 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15 96.84
121 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22 96.84
122 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 96.84
123 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 96.84
124 INT12281 Negative_regulation of Gene_expression of Npy 23 0.59 7.45 13.41 96.72
125 INT70970 Binding of COPD 144 0.42 180.34 18.29 96.72
126 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 96.72
127 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11 96.72
128 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 96.68
129 INT353445 Positive_regulation of PSG5 1 0.26 0.65 0.14 96.64
130 INT156210 Regulation of Positive_regulation of Drd4 1 0.45 0.72 0.49 96.60
131 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03 96.56
132 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29 96.56
133 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35 96.56
134 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.52
135 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 96.52
136 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 96.52
137 INT28593 Gene_expression of Dbt 4 0.53 3.08 0.73 96.40
138 INT276 Regulation of Ache 83 0.62 16.75 25.99 96.36
139 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17 96.32
140 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36 96.32
141 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 96.32
142 INT149607 Gene_expression of Labx 1 0.58 0.29 0.1 96.20
143 INT149608 Binding of Labx 1 0.32 0.29 0.1 96.20
144 INT241467 Negative_regulation of Impdh1 1 0.01 1.45 0.27 96.12
145 INT300587 Negative_regulation of Gene_expression of Cartpt 3 0.36 0.58 2.19 96.08
146 INT76596 Gene_expression of BCAT1 5 0.58 0.73 1.32 95.96
147 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 95.96
148 INT7287 Positive_regulation of Transcription of Penk 103 0.70 19.81 50.37 95.96
149 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 95.92
150 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 95.88
151 INT738 Regulation of POMC 459 0.62 111.19 243.74 95.88
152 INT82284 Negative_regulation of Gene_expression of Arc 10 0.41 4.26 2.58 95.84
153 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 95.84
154 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44 95.84
155 INT20462 Binding of ESR1 210 0.44 102.7 26.34 95.84
156 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 95.80
157 INT8603 Binding of Mme 28 0.48 1.42 7.64 95.80
158 INT126907 Positive_regulation of Gene_expression of CD68 8 0.42 10.94 1.23 95.72
159 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 95.72
160 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 95.68
161 INT88274 Positive_regulation of Drd4 7 0.69 3.48 4.1 95.68
162 INT88273 Gene_expression of Drd4 6 0.54 1.84 3.01 95.64
163 INT138083 Positive_regulation of Gene_expression of Drd4 2 0.40 1.34 1.55 95.64
164 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 95.64
165 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 95.64
166 INT162831 Regulation of ARSD 13 0.35 6.17 1.19 95.60
167 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 95.60
168 INT69498 Positive_regulation of DRD4 3 0.50 0.95 1.3 95.56
169 INT79597 Positive_regulation of Negative_regulation of PDE5A 5 0.50 3.39 0.41 95.48
170 INT29556 Negative_regulation of CALM1 26 0.57 9.08 6.04 95.40
171 INT4803 Transcription of Penk 435 0.72 59.09 182.4 95.28
172 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 95.28
173 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 95.16
174 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 95.16
175 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 95.16
176 INT201010 Negative_regulation of CALM2 1 0.34 2.73 1.57 95.12
177 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 95.12
178 INT129666 Gene_expression of Nrcam 5 0.78 3.97 1.01 95.12
179 INT270 Regulation of MAOA 17 0.60 2.58 6.84 95.08
180 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 95.04
181 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 94.96
182 INT5854 Regulation of Gene_expression of Penk 22 0.61 6.91 10.03 94.96
183 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 94.96
184 INT50315 Positive_regulation of htr 20 0.61 1.96 11.22 94.88
185 INT292608 Positive_regulation of Regulation of GABRB3 1 0.05 1.58 0.45 94.88
186 INT261712 Regulation of GABRB3 6 0.09 3.03 3.14 94.88
187 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56 94.84
188 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 94.80
189 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 94.76
190 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 94.72
191 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 94.72
192 INT79298 Localization of NXT1 9 0.60 4.9 3.42 94.72
193 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 94.72
194 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 94.72
195 INT16569 Negative_regulation of HTR3A 14 0.57 6.91 4.42 94.52
196 INT65638 Negative_regulation of Gene_expression of Il1rl1 12 0.58 7.86 11.7 94.44
197 INT246706 Binding of Salc1 5 0.08 3.29 0.52 94.40
198 INT67308 Positive_regulation of NISCH 3 0.62 1.21 1.22 94.36
199 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22 94.20
200 INT200972 Positive_regulation of Gene_expression of UPF1 6 0.31 1.51 1.23 94.16
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