P:ergotamine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 641
Hot Single Events 30
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for ergotamine. They are ordered first by their pain relevance and then by number of times they were reported for ergotamine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21 61.44
2 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for ergotamine. They are ordered first by their pain relevance and then by number of times they were reported in ergotamine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT77371 Regulation of Regulation of Cebpz 4 0.45 0.45 2.42 100.00
2 INT12333 Regulation of CYP3A 18 0.62 2.25 6.74 99.80
3 INT2330 Regulation of CB 78 0.10 20.46 32.6 99.52
4 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 99.10
5 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94 99.04
6 INT6520 Regulation of Gene_expression of ADRA1D 5 0.44 1.15 1.18 98.90
7 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52 98.90
8 INT6594 Gene_expression of HTR1D 60 0.75 10.15 27.13 98.82
9 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 98.68
10 INT9782 Binding of HTR1B 43 0.47 12.08 19.83 98.64
11 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 98.64
12 INT11703 Regulation of Es2 7 0.39 3.23 4.91 98.04
13 INT13501 Binding of Drd2 65 0.48 23.76 35.6 97.60
14 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 97.58
15 INT116220 Localization of HTR1B 5 0.78 1.86 3.75 96.48
16 INT2893 Localization of Oxt 219 0.80 28.96 79.43 95.40
17 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 94.36
18 INT59790 Binding of BCR 16 0.36 15.34 1.75 94.20
19 INT270 Regulation of MAOA 17 0.60 2.58 6.84 92.72
20 INT60821 Negative_regulation of HTR1D 15 0.57 0.69 5.27 92.64
21 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43 92.24
22 INT20071 Positive_regulation of HTR2A 33 0.67 10.89 14 92.16
23 INT31809 Gene_expression of HTR2B 5 0.75 2.3 2.44 91.96
24 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8 88.60
25 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74 88.60
26 INT626 Localization of CALCA 289 0.81 125.39 221.15 88.32
27 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 87.04
28 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 86.08
29 INT158 Localization of Prl 2431 0.81 378.96 952.2 85.28
30 INT9358 Positive_regulation of HTR1B 26 0.67 11 17.51 80.24
31 INT83313 Gene_expression of Htr1b 4 0.75 5.1 5.73 79.12
32 INT139613 Binding of pr 16 0.47 5.52 8.46 77.52
33 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 76.96
34 INT691 Binding of SST 67 0.48 24.66 32.67 73.92
35 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8 73.24
36 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 72.72
37 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 72.56
38 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 72.12
39 INT47886 Binding of Cc2d1a 1 0.02 0.57 0.44 70.08
40 INT2065 Binding of BTG3 15 0.36 10.9 4.65 69.08
41 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36 64.16
42 INT10059 Binding of CSH1 17 0.35 5.28 3.37 61.84
43 INT1448 Binding of Adra1a 23 0.48 1.41 8.01 61.44
44 INT59969 Positive_regulation of Htr1a 12 0.67 5.07 5.73 60.68
45 INT78493 Negative_regulation of F3 11 0.27 8.35 3.76 60.52
46 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 55.44
47 INT127777 Positive_regulation of Mthfr 4 0.38 3.8 2.09 50.64
48 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 50.56
49 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13 50.56
50 INT1645 Negative_regulation of CSH1 20 0.42 1.71 3.7 49.76
51 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 47.96
52 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 45.12
53 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 37.84
54 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 25.00
55 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 25.00
56 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 25.00
57 INT8766 Positive_regulation of Positive_regulation of CYP2B6 5 0.49 3.41 1.97 25.00
58 INT18771 Positive_regulation of Positive_regulation of CSH1 1 0.36 0 0 25.00
59 INT22187 Localization of HTR1D 6 0.78 5.26 5.97 21.68
60 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 19.00
61 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 18.48
62 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 15.96
63 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66 15.64
64 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 14.68
65 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 11.88
66 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 10.56
67 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
68 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
69 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
70 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
71 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 5.00
72 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
73 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
74 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
75 INT6761 Binding of CALCA 100 0.48 26.71 62.05 5.00
76 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
77 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 5.00
78 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
79 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 5.00
80 INT4776 Localization of TAC1 82 0.78 16.89 45.21 5.00
81 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
82 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
83 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
84 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 5.00
85 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
86 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 5.00
87 INT36428 Binding of Chdh 42 0.47 48.04 26.54 5.00
88 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
89 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01 5.00
90 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
91 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
92 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 5.00
93 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
94 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
95 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 5.00
96 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
97 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
98 INT99058 Regulation of PAG1 18 0.45 21.62 18.5 5.00
99 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
100 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 5.00
101 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
102 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
103 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
104 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
105 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
106 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
107 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
108 INT50580 Binding of PPIG 39 0.36 11.17 12.34 5.00
109 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22 5.00
110 INT5464 Regulation of CALCRL 24 0.16 4.2 11.19 5.00
111 INT4804 Positive_regulation of Gene_expression of PTGDS 10 0.68 21.43 11.14 5.00
112 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
113 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
114 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
115 INT32581 Positive_regulation of C4B 9 0.45 11.17 9.05 5.00
116 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 5.00
117 INT83607 Positive_regulation of CSAD 13 0.59 14.24 8.07 5.00
118 INT6884 Negative_regulation of pr 20 0.42 13.18 7.97 5.00
119 INT32579 Binding of C4B 14 0.36 14.99 7.79 5.00
120 INT32580 Gene_expression of C4B 24 0.75 17.95 7.75 5.00
121 INT96619 Negative_regulation of CSAD 7 0.36 8.96 7.47 5.00
122 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17 5.00
123 INT264641 Binding of AES 25 0.42 18.56 6.98 5.00
124 INT4810 Localization of PTGDS 20 0.81 4.19 6.97 5.00
125 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 5.00
126 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61 5.00
127 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87 5.00
128 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
129 INT180035 Positive_regulation of Gene_expression of Chdh 2 0.22 8.21 5.78 5.00
130 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6 5.00
131 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
132 INT106131 Negative_regulation of Abcc3 8 0.58 3.17 4.86 5.00
133 INT98613 Gene_expression of CSAD 7 0.53 7.86 4.8 5.00
134 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76 5.00
135 INT33466 Negative_regulation of C4B 14 0.43 9.06 4.64 5.00
136 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5 5.00
137 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62 5.00
138 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 5.00
139 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 5.00
140 INT4488 Gene_expression of TSHB 10 0.41 4.69 3.09 5.00
141 INT39344 Gene_expression of DNASE1L3 12 0.54 2.25 2.88 5.00
142 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63 5.00
143 INT122557 Localization of Chdh 6 0.74 4.44 2.6 5.00
144 INT65948 Binding of DNASE1L3 8 0.31 1.38 2.21 5.00
145 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18 5.00
146 INT66117 Negative_regulation of MILR1 4 0.37 1.34 2.12 5.00
147 INT216065 Localization of C4B 2 0.21 2.86 2.01 5.00
148 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93 5.00
149 INT180907 Positive_regulation of COQ10A 21 0.60 3.26 1.88 5.00
150 INT64378 Gene_expression of DMRT1 9 0.54 1.72 1.71 5.00
151 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 5.00
152 INT160553 Regulation of C4B 3 0.14 1.54 1.16 5.00
153 INT37679 Positive_regulation of HLA-DRB4 12 0.34 11.93 1.16 5.00
154 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06 5.00
155 INT264642 Gene_expression of SEC14L2 1 0.35 0.46 1 5.00
156 INT115845 Positive_regulation of Gene_expression of DNASE1L3 2 0.40 0.58 0.9 5.00
157 INT137276 Binding of Acads 3 0.32 1.82 0.84 5.00
158 INT243845 Localization of MAOA 4 0.55 1.52 0.77 5.00
159 INT169880 Gene_expression of MILR1 2 0.03 0.41 0.66 5.00
160 INT242745 Regulation of FANCE 2 0.28 1.98 0.66 5.00
161 INT312653 Negative_regulation of GOLPH3 1 0.06 1.08 0.59 5.00
162 INT120591 Positive_regulation of Acads 2 0.40 1.25 0.56 5.00
163 INT312652 Protein_catabolism of GOLPH3 1 0.09 0.9 0.56 5.00
164 INT232494 Localization of RANGAP1 5 0.11 1.5 0.49 5.00
165 INT224010 Negative_regulation of ENTPD1 4 0.16 1.27 0.41 5.00
166 INT233109 Regulation of Positive_regulation of CALCA 1 0.30 0.23 0.36 5.00
167 INT125798 Localization of MILR1 2 0.14 0.77 0.33 5.00
168 INT219198 Gene_expression of RANGAP1 3 0.30 0.94 0.2 5.00
169 INT233110 Regulation of Localization of MILR1 1 0.02 0.32 0.19 5.00
170 INT264065 Protein_catabolism of Lrtomt 1 0.01 0.63 0.14 5.00
171 INT232495 Gene_expression of VDAC1 1 0.06 0.64 0.06 5.00
172 INT282818 Negative_regulation of DNASE1L3 1 0.13 0.1 0.06 5.00
173 INT183819 Negative_regulation of Positive_regulation of BCAR1 1 0.38 2.04 0.05 5.00
174 INT183818 Positive_regulation of MKKS 1 0.01 1.82 0.05 5.00
175 INT282816 Localization of DMRT1 1 0.05 0 0 5.00
176 INT282819 Localization of DNASE1L3 1 0.24 0 0 5.00
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