P:fluoxetine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific Yes
Documents 7227
Hot Single Events 200
Hot Interactions 167

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for fluoxetine. They are ordered first by their pain relevance and then by number of times they were reported for fluoxetine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99 100.00
2 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31 100.00
3 INT192873 Binding of RS1 and Nktcn1 1 0.00 0.8 0.59 100.00
4 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76 100.00
5 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67 100.00
6 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67 100.00
7 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89 100.00
8 INT162288 Regulation of Binding of TUBA1A and Phospho2 1 0.24 1.28 0.4 100.00
9 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 100.00
10 INT137099 Dlst Regulation of Sec22b 1 0.05 0 0.64 99.92
11 INT137100 Dlst Regulation of Htr1a 1 0.18 0 0.64 99.92
12 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92 99.84
13 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91 99.84
14 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81 99.84
15 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96 99.84
16 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96 99.84
17 INT135364 Prr14 Positive_regulation of Mbd1 1 0.22 0.15 0.64 99.84
18 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64 99.84
19 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64 99.84
20 INT146087 Abcb1b Regulation of Binding of Abcb1a 1 0.49 0.09 0.34 99.46
21 INT146088 Abcb1b Regulation of Abcb1a 1 0.49 0.09 0.34 99.46
22 INT162289 Binding of TUBA1A and Phospho2 1 0.31 1.26 0.4 99.44
23 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79 99.40
24 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79 99.40
25 INT44502 Regulation of Mt1a Positive_regulation of Prl 1 0.14 0 0.74 99.32
26 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07 99.30
27 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81 99.24
28 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36 99.12
29 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36 99.12
30 INT69709 NPL Positive_regulation of Localization of POMC 2 0.36 1.22 1.51 99.00
31 INT44505 Mt1a Positive_regulation of Mt1a Positive_regulation of Prl 1 0.19 0 1.48 98.98
32 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48 98.98
33 INT141171 Ptz1a Positive_regulation of Gene_expression of Fos 1 0.07 0.5 0.69 98.84
34 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75 98.76
35 INT90959 PPIG Regulation of CYP2C9 1 0.43 0 0.75 98.72
36 INT137103 Sec22b Regulation of Htr1a 1 0.09 0 1.02 98.72
37 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02 98.72
38 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74 98.72
39 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76 98.68
40 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76 98.68
41 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4 98.66
42 INT111813 CREM Regulation of Regulation of CRH 1 0.12 0 0.3 98.64
43 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95 98.60
44 INT164135 Binding of Drd2 and Prl 1 0.04 0 0.22 98.52
45 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05 98.50
46 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9 98.50
47 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9 98.50
48 INT2000 ASNA1 Positive_regulation of Localization of PRL 1 0.07 0 0.79 98.40
49 INT129313 HTR2A Positive_regulation of Oxt 1 0.41 0.22 0.67 98.38
50 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69 98.28
51 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69 98.28
52 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69 98.28
53 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69 98.28
54 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69 98.28
55 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69 98.28
56 INT135203 Ighen Regulation of Gene_expression of Gmeb1 1 0.03 0.48 0.69 98.28
57 INT135215 Nfkb1 Regulation of Gene_expression of Gmeb1 1 0.01 0.48 0.69 98.28
58 INT135209 Gmeb1 Regulation of Gene_expression of Ighen 1 0.02 0.48 0.69 98.28
59 INT135214 Gmeb1 Regulation of Gene_expression of Nfkb1 1 0.01 0.48 0.69 98.28
60 INT135210 Ighen Regulation of Gene_expression of Nfkb1 1 0.01 0.47 0.68 98.28
61 INT135212 Nfkb1 Regulation of Gene_expression of Ighen 1 0.01 0.47 0.68 98.28
62 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14 98.12
63 INT296172 Fig4 Positive_regulation of Gene_expression of NOVA2 1 0.04 0 0.22 98.08
64 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41 98.04
65 INT161747 Positive_regulation of Binding of G6PD and HBG2 1 0.28 0.18 0.1 98.00
66 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 97.96
67 INT164136 Binding of DRD2 and Prl 1 0.09 0 0.22 97.64
68 INT79614 Negative_regulation of Htr1a Positive_regulation of Oxt 1 0.38 0 0.38 97.52
69 INT40855 GGH Regulation of PRL 1 0.10 0 0.32 97.46
70 INT161746 Binding of G6PD and HBG2 1 0.21 0.36 0.19 97.40
71 INT49716 PCA Negative_regulation of Nr3c2 1 0.02 0 0.41 97.28
72 INT79617 Htr1a Positive_regulation of Localization of POMC 1 0.38 0 0.83 97.16
73 INT79616 Htr1a Positive_regulation of Localization of Oxt 1 0.44 0 0.41 97.16
74 INT79618 Htr1a Positive_regulation of POMC 1 0.17 0 0.39 97.16
75 INT79615 Htr1a Positive_regulation of Oxt 1 0.44 0 0.38 97.16
76 INT46400 Negative_regulation of Drd3 Positive_regulation of Localization of Prl 1 0.15 0.09 0.22 97.00
77 INT46399 Negative_regulation of Drd3 Positive_regulation of Prl 1 0.15 0.09 0.22 97.00
78 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52 96.60
79 INT122873 SEMA6A Positive_regulation of SGSM3 1 0.54 0 0.26 96.60
80 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5 96.16
81 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95 96.12
82 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38 96.12
83 INT57674 ecs Regulation of htr 1 0.01 0.15 0.35 95.92
84 INT69767 Binding of Htr1a and Ptgdr 1 0.23 0 0.97 95.36
85 INT263090 Negative_regulation of Binding of FDX1 and LH 1 0.02 0.95 0.32 95.12
86 INT46432 Prl Negative_regulation of Prss12 1 0.16 0 0.3 94.88
87 INT45947 Nts Negative_regulation of Gene_expression of Prl 1 0.26 0 0.17 94.88
88 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56 94.84
89 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34 94.80
90 INT263091 Binding of FDX1 and LH 1 0.02 0.95 0.32 94.72
91 INT45946 Nts Negative_regulation of Prl 2 0.50 0 0.71 94.60
92 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29 94.48
93 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57 94.40
94 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57 94.40
95 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57 94.40
96 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56 94.40
97 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 94.34
98 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65 94.28
99 INT936 Spic Positive_regulation of Localization of Prl 1 0.09 0 0.31 93.88
100 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69 93.72
101 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69 93.72
102 INT160156 Tph2 Regulation of Htr1a 1 0.30 0.75 0.56 93.64
103 INT253165 SCN10A Positive_regulation of OVGP1 1 0.06 1.34 0.61 93.36
104 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 93.36
105 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14 92.88
106 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52 92.80
107 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12 92.72
108 INT134029 Olr696 Regulation of Ldha 1 0.00 0.15 0.68 92.64
109 INT134027 Olr696 Regulation of Drp2 1 0.01 0.15 0.68 92.64
110 INT134028 Olr696 Regulation of Trib3 1 0.00 0.15 0.68 92.64
111 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91 92.40
112 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 92.40
113 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 92.28
114 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51 91.48
115 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 91.40
116 INT775 Nts Positive_regulation of Gnrhr 2 0.18 0 1.02 91.32
117 INT45948 Nts Negative_regulation of LH 1 0.18 0 0.35 91.32
118 INT151895 Binding of CYP3A4 and GBE1 1 0.01 0.24 0.18 90.24
119 INT291568 Artles Regulation of Cstb 1 0.00 0.7 0.3 90.00
120 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33 89.68
121 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26 89.60
122 INT118210 Ghrl Negative_regulation of Prl 1 0.53 0 0.33 89.56
123 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66 89.20
124 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56 89.08
125 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51 88.96
126 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57 88.76
127 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57 88.76
128 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55 88.36
129 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 0.47 0.06 0.16 88.00
130 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89 87.84
131 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56 87.32
132 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 86.96
133 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 86.88
134 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7 86.32
135 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65 86.24
136 INT28032 TNIP3 Negative_regulation of Acot1 1 0.00 0 0.47 86.16
137 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53 86.08
138 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51 85.72
139 INT117483 SFXN3 Negative_regulation of THRB 1 0.15 0.15 0.51 85.72
140 INT84283 Binding of Adra2a and Htr1f 1 0.16 0.15 0.74 85.12
141 INT74395 Htr2b Negative_regulation of Pdyn 1 0.03 0 0.61 85.04
142 INT46434 Prss12 Negative_regulation of Prl 1 0.16 0 0.54 84.88
143 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 84.88
144 INT104325 Regulation of Fen1 Negative_regulation of Baat 1 0.19 0.75 0.12 84.88
145 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25 84.24
146 INT141315 Gs Regulation of Kcnk10 1 0.16 0.64 0.27 84.24
147 INT141314 Gs Regulation of Kcnk4 1 0.19 0.64 0.27 84.24
148 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88 84.16
149 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43 83.84
150 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57 83.72
151 INT143619 Bhlhe22 Positive_regulation of Regulation of Msr1 1 0.40 0.93 0.46 83.56
152 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94 83.52
153 INT104327 Fen1 Negative_regulation of Baat 1 0.31 0.75 0.12 83.44
154 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 83.36
155 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1 83.08
156 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61 82.72
157 INT46433 Nts Negative_regulation of Prss12 1 0.12 0 0.27 82.72
158 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49 82.48
159 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65 82.48
160 INT118208 Ghrl Negative_regulation of Localization of Prl 1 0.39 0 0.44 81.88
161 INT315333 Binding of Cflar and Fadd 1 0.01 0.49 0.42 81.36
162 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74 81.04
163 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67 80.60
164 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16 80.36
165 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67 80.32
166 INT113249 Olr1259 Negative_regulation of Sert1 1 0.01 0.15 0.4 80.24
167 INT45944 Nts Regulation of Localization of Cga 1 0.20 0 0.15 80.24
168 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37 79.88
169 INT49717 PCA Regulation of Nr3c2 1 0.01 0 0.27 79.72
170 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83 79.52
171 INT164476 Negative_regulation of Binding of Bche and Frl 1 0.02 0.48 0.51 79.28
172 INT164475 Binding of Bche and Frl 1 0.02 0.48 0.51 79.28
173 INT45945 Nts Positive_regulation of Localization of Prl 1 0.34 0 0.2 78.96
174 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 78.36
175 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24 77.96
176 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14 77.76
177 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85 77.48
178 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44 77.48
179 INT128432 HTR1B Regulation of S100A4 1 0.49 0.28 0.24 77.28
180 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 76.48
181 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 76.48
182 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53 76.48
183 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49 75.76
184 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51 75.60
185 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05 75.00
186 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5 75.00
187 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41 75.00
188 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19 75.00
189 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28 74.96
190 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63 74.56
191 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86 74.08
192 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6 74.08
193 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46 74.00
194 INT70422 Binding of Htr1a and Adarb1 1 0.01 0.37 0.81 73.72
195 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31 73.44
196 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31 72.20
197 INT167982 Mapk14 Negative_regulation of gr 1 0.02 0.45 0.29 71.80
198 INT334180 Tdo2 Negative_regulation of Tbpl1 1 0.10 0.16 0.45 71.12
199 INT16859 Maob Negative_regulation of Maoa 1 0.36 0 0.11 71.04
200 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 71.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for fluoxetine. They are ordered first by their pain relevance and then by number of times they were reported in fluoxetine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 100.00
3 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 100.00
4 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
5 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 100.00
6 INT116121 Binding of Nfx1 1 0.41 0 8.06 100.00
7 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 100.00
8 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 100.00
9 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 100.00
10 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 100.00
11 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 100.00
12 INT8122 Regulation of Htr1a 39 0.60 8.96 24.89 100.00
13 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
14 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 100.00
15 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
16 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
17 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28 100.00
18 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
19 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
20 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 100.00
21 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
22 INT116119 Gene_expression of Nfx1 1 0.75 0 3.72 100.00
23 INT16714 Regulation of Creb1 64 0.62 22.23 33.56 100.00
24 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55 100.00
25 INT56775 Binding of Htr2c 16 0.47 3.77 8.74 100.00
26 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 100.00
27 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
28 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 100.00
29 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 100.00
30 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2 100.00
31 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
32 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28 100.00
33 INT73641 Regulation of Lep 45 0.62 26.2 12.59 100.00
34 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 100.00
35 INT79396 Regulation of Gene_expression of Pde4a 6 0.59 1.45 4.12 100.00
36 INT137688 Regulation of Gene_expression of Ncam1 1 0.60 1.21 3.65 100.00
37 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81 100.00
38 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 100.00
39 INT72322 Positive_regulation of Localization of Htr1a 5 0.49 0 3.08 100.00
40 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 100.00
41 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08 100.00
42 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
43 INT27258 Regulation of Htr2a 18 0.60 6.37 11.06 100.00
44 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14 100.00
45 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17 100.00
46 INT6892 Regulation of Htr1b 9 0.60 1.32 7.24 100.00
47 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11 100.00
48 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 100.00
49 INT121946 Positive_regulation of Pld3 1 0.08 0.15 1.55 100.00
50 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46 100.00
51 INT118672 Regulation of Camkk1 2 0.56 1.37 2.23 100.00
52 INT132891 Gene_expression of CHUK 1 0.01 0.47 1.58 100.00
53 INT132890 Positive_regulation of Binding of CHUK 1 0.00 0.44 1.6 100.00
54 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
55 INT22713 Binding of FL 5 0.19 1.73 2.55 100.00
56 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 100.00
57 INT119524 Regulation of Camkk2 4 0.25 1.62 3.35 100.00
58 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 100.00
59 INT75746 Regulation of ZMYND10 3 0.44 0.5 1.31 100.00
60 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 100.00
61 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
62 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9 100.00
63 INT147283 Regulation of Gene_expression of Tph2 2 0.62 0.22 3.05 100.00
64 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 100.00
65 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79 100.00
66 INT27785 Regulation of HTR2A 11 0.44 8 8.18 100.00
67 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 100.00
68 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57 100.00
69 INT94132 Binding of ACOT1 7 0.13 2.62 4.04 100.00
70 INT33237 Regulation of Fst 10 0.39 1.3 3 100.00
71 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05 100.00
72 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37 100.00
73 INT130996 Positive_regulation of Regulation of CYP2C9 1 0.34 0 1 100.00
74 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01 100.00
75 INT136787 Regulation of Regulation of Eef2 1 0.45 0 1.18 100.00
76 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16 100.00
77 INT922 Regulation of Positive_regulation of PRL 7 0.60 3.57 3.95 100.00
78 INT138673 Regulation of Gene_expression of TPH2 3 0.62 1.23 1.42 100.00
79 INT91646 Regulation of HTR5BP 1 0.23 0 1.6 100.00
80 INT65948 Binding of DNASE1L3 8 0.31 1.38 2.21 100.00
81 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56 100.00
82 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 100.00
83 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 100.00
84 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
85 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23 100.00
86 INT173754 Regulation of Mki67 4 0.06 1.04 1.61 100.00
87 INT192868 Binding of Nktcn1 1 0.00 0.33 0.7 100.00
88 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 100.00
89 INT121948 Negative_regulation of Positive_regulation of Pld3 1 0.06 0.07 0.77 100.00
90 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 0.20 0.07 0.76 100.00
91 INT75908 Regulation of LEP 77 0.60 60.16 15.19 100.00
92 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 100.00
93 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 100.00
94 INT5997 Regulation of Glyr1 3 0.38 0.34 1.38 100.00
95 INT102541 Binding of Tia1 3 0.26 0.68 1.64 100.00
96 INT78581 Positive_regulation of Binding of Nfkb1 13 0.66 7.37 2.79 100.00
97 INT3530 Regulation of BCHE 18 0.60 5.47 4.12 100.00
98 INT49842 Regulation of Gene_expression of Htr2a 2 0.44 0.18 0.88 100.00
99 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04 100.00
100 INT35325 Regulation of Localization of CA2 10 0.32 1.13 1.69 100.00
101 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 100.00
102 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51 100.00
103 INT91354 Regulation of HCL1 1 0.00 0 0.71 100.00
104 INT55236 Regulation of Htr2c 6 0.44 3.31 3.36 100.00
105 INT72321 Regulation of Negative_regulation of Adarb1 2 0.07 0.15 1.22 100.00
106 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32 100.00
107 INT61706 Regulation of Gene_expression of Gal 17 0.62 10.09 11.96 100.00
108 INT140449 Positive_regulation of Tap1 5 0.68 1.84 0.74 100.00
109 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
110 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
111 INT119751 Positive_regulation of Gene_expression of Fbgl1 1 0.49 0.42 0.58 100.00
112 INT153120 Gene_expression of Gnmt 2 0.02 0.17 0.78 100.00
113 INT131219 Gene_expression of Nmi 2 0.52 0.64 1.15 100.00
114 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17 100.00
115 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
116 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 100.00
117 INT96318 Regulation of Transcription of gr 1 0.59 2.35 0.96 100.00
118 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
119 INT128320 Regulation of Gene_expression of Npas2 1 0.43 0.18 1.38 100.00
120 INT29772 Positive_regulation of Positive_regulation of Ache 3 0.50 0.09 1.18 100.00
121 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18 100.00
122 INT9311 Regulation of Ssr1 13 0.60 6.41 6.58 100.00
123 INT146300 Binding of RS1 31 0.22 29.55 3.04 100.00
124 INT7577 Regulation of Nr3c2 16 0.56 7.7 10.1 100.00
125 INT133836 Regulation of Positive_regulation of Cyp2c6 1 0.27 0 0.64 100.00
126 INT79699 Regulation of Cyp2a 1 0.55 0.46 1.62 100.00
127 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01 100.00
128 INT137689 Regulation of Gene_expression of Cfp 4 0.23 0.91 1.7 100.00
129 INT140286 Binding of CGF1 3 0.07 7.78 0.97 100.00
130 INT12333 Regulation of CYP3A 18 0.62 2.25 6.74 100.00
131 INT156213 Regulation of Cort 6 0.39 7.5 1.54 100.00
132 INT2842 Positive_regulation of Binding of Prl 3 0.50 0 0.59 100.00
133 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26 100.00
134 INT89101 Negative_regulation of Negative_regulation of HTR7 1 0.42 0 0.5 100.00
135 INT89102 Positive_regulation of Localization of HTR7 1 0.49 0 0.5 100.00
136 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51 100.00
137 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 100.00
138 INT11605 Regulation of Positive_regulation of Gh 10 0.45 2.08 3.85 100.00
139 INT119609 Regulation of CHRNE 1 0.05 0.36 0.46 100.00
140 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45 100.00
141 INT45392 Regulation of CHRM1 3 0.26 0.52 2.25 100.00
142 INT13705 Regulation of Pebp1 2 0.26 0.85 1.3 100.00
143 INT128318 Regulation of Gene_expression of Aanat 1 0.33 0.09 0.76 100.00
144 INT84059 Negative_regulation of Negative_regulation of Avpr1a 1 0.41 0.64 0.46 100.00
145 INT168658 Regulation of Gene_expression of HTR1B 2 0.44 2.11 2.44 100.00
146 INT5515 Negative_regulation of Positive_regulation of Pomc 25 0.58 8.73 11.88 100.00
147 INT167456 Regulation of Gene_expression of Nr3c1 2 0.14 0.76 1.87 100.00
148 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
149 INT48931 Regulation of Regulation of Trib3 2 0.04 0.06 0.89 100.00
150 INT116221 Positive_regulation of Localization of HTR1B 1 0.49 0.07 0.56 100.00
151 INT91598 Positive_regulation of Localization of HTR1A 3 0.49 0.51 1.03 100.00
152 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 100.00
153 INT57673 Regulation of Positive_regulation of htr 2 0.24 0.27 1.76 100.00
154 INT160105 Binding of Tst 6 0.31 1.23 1.56 100.00
155 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59 100.00
156 INT118492 Regulation of Pde4a 7 0.61 6.32 6.04 100.00
157 INT167140 Negative_regulation of Es3 1 0.00 0 0.33 100.00
158 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68 100.00
159 INT128321 Regulation of Gene_expression of Cry1 2 0.34 0.09 1.38 100.00
160 INT128316 Regulation of Gene_expression of Arntl 6 0.43 0.68 1.43 100.00
161 INT128323 Regulation of Gene_expression of Per3 1 0.21 0.09 0.69 100.00
162 INT128327 Regulation of Gene_expression of Per2 9 0.45 1.11 1.66 100.00
163 INT128324 Regulation of Gene_expression of Per1 11 0.61 1.95 5.22 100.00
164 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41 100.00
165 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4 100.00
166 INT161744 Negative_regulation of Negative_regulation of Slc18a2 1 0.40 2.82 0.9 100.00
167 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
168 INT50312 Positive_regulation of Positive_regulation of htr 2 0.58 0.09 0.67 100.00
169 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06 100.00
170 INT315328 Negative_regulation of Gene_expression of Cflar 1 0.03 0.49 0.39 100.00
171 INT315330 Negative_regulation of Positive_regulation of Cflar 1 0.03 0.49 0.38 100.00
172 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59 100.00
173 INT137955 Regulation of MTG1 1 0.44 0.19 0.37 100.00
174 INT45012 Negative_regulation of Azi1 1 0.37 0.18 0.43 100.00
175 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 100.00
176 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
177 INT1511 Negative_regulation of Binding of Prl 7 0.59 1.64 2.19 100.00
178 INT133526 Regulation of Transcription of HTR1B 1 0.26 0 0.55 100.00
179 INT921 Regulation of GH1 172 0.60 52.88 51.04 100.00
180 INT250 Regulation of GHRH 65 0.61 17.46 23.19 100.00
181 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76 100.00
182 INT133835 Regulation of Cyp2c6 1 0.45 0 0.69 100.00
183 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 100.00
184 INT122041 Binding of Ppara 308 0.48 189.17 51.48 100.00
185 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1 100.00
186 INT7138 Regulation of Regulation of Avp 10 0.36 1.99 6.37 100.00
187 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15 100.00
188 INT7139 Regulation of Regulation of Oxt 3 0.44 0.09 1.34 100.00
189 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8 100.00
190 INT120699 Negative_regulation of Negative_regulation of MAOB 1 0.43 0.26 0.54 100.00
191 INT109573 Regulation of Ncl-ps1 1 0.08 0 0.25 100.00
192 INT9039 Negative_regulation of Htr1a 69 0.57 9.56 41.84 99.98
193 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.98
194 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 99.98
195 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 99.98
196 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.98
197 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 99.98
198 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 99.98
199 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 99.98
200 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.98
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