P:hyperexcitability

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Pain Term
Category Process
Synonyms None
Pain Specific No
Documents 947
Hot Single Events 200
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for hyperexcitability. They are ordered first by their pain relevance and then by number of times they were reported for hyperexcitability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68 99.68
2 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08 96.00
3 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18 94.48
4 INT120834 Binding of CNTN1 and SCN3A 1 0.01 0.41 0.49 94.12
5 INT150333 4930519F16Rik Positive_regulation of F2rl1 1 0.00 0.67 0.38 93.12
6 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61 91.84
7 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82 90.08
8 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44 89.76
9 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9 89.72
10 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73 87.84
11 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65 87.60
12 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45 85.00
13 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45 85.00
14 INT151252 CSAD Positive_regulation of Positive_regulation of Ltp 1 0.06 0.81 0.67 84.72
15 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01 83.00
16 INT61345 Iapp Regulation of GAL 2 0.08 0.35 0.41 80.52
17 INT273983 Abat Regulation of Gene_expression of Ascc1 1 0.07 0 0.34 79.52
18 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 78.96
19 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 78.96
20 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86 78.56
21 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97 77.44
22 INT273982 Ascc1 Regulation of Localization of Abat 1 0.04 0 0.35 75.72
23 INT157709 CRX Positive_regulation of Mpo 1 0.08 1.11 0.5 75.00
24 INT352060 SLC22A12 Negative_regulation of CASZ1 1 0.07 0.62 0.12 72.88
25 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47 71.60
26 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 71.28
27 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 71.28
28 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 71.28
29 INT227544 Hspa9 Regulation of Gene_expression of Prep 1 0.15 0.57 0.61 71.28
30 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25 71.24
31 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72 70.56
32 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38 69.80
33 INT151251 CSAD Regulation of Positive_regulation of Ltp 1 0.04 0.82 0.65 68.16
34 INT166222 Gene_expression of Fos Positive_regulation of Col6a6 1 0.01 0.57 0.77 65.32
35 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 63.60
36 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 63.60
37 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15 63.28
38 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 62.80
39 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14 61.44
40 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44 60.00
41 INT276688 Positive_regulation of Prkcg Positive_regulation of Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.46 59.96
42 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37 59.96
43 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43 54.84
44 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45 53.60
45 INT276675 Binding of Nkx1-1 and Nav1 1 0.09 0.21 1.46 53.36
46 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3 52.96
47 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 52.08
48 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31 49.08
49 INT276678 Nkx1-1 Regulation of Nav1 1 0.15 0.88 3.31 42.80
50 INT114811 Kcna7 Regulation of KCNQ2 1 0.00 0.69 0.13 40.72
51 INT114810 KCNQ3 Regulation of KCNQ2 1 0.05 0.35 0.06 40.32
52 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19 40.20
53 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55 39.12
54 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12 38.24
55 INT257220 Binding of Nos1 and Flvcr2 1 0.00 0.17 0.47 36.72
56 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 31.28
57 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 31.28
58 INT149346 Negative_regulation of Kcnab1 Positive_regulation of Kcna1 1 0.01 0.08 0.18 29.04
59 INT149345 Kcnab1 Negative_regulation of Kcna1 1 0.01 0.08 0.18 29.04
60 INT149344 Kcnab1 Positive_regulation of Kcna1 1 0.01 0.08 0.18 29.04
61 INT149343 Negative_regulation of Kcnab1 Negative_regulation of Kcna1 1 0.01 0.08 0.18 29.04
62 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91 20.20
63 INT273985 Ascc1 Negative_regulation of Localization of Abat 1 0.07 0 0.14 19.40
64 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1 8.40
65 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22 7.84
66 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55 7.44
67 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55 7.44
68 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9 5.72
69 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55 5.52
70 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55 5.12
71 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
72 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
73 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
74 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
75 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
76 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29 5.00
77 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
78 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08 5.00
79 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84 5.00
80 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
81 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
82 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
83 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46 5.00
84 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46 5.00
85 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
86 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27 5.00
87 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
88 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
89 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
90 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98 5.00
91 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92 5.00
92 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92 5.00
93 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85 5.00
94 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82 5.00
95 INT276674 Negative_regulation of Nkx1-1 Regulation of Nav1 1 0.11 0.68 1.81 5.00
96 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67 5.00
97 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66 5.00
98 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6 5.00
99 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
100 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54 5.00
101 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49 5.00
102 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
103 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
104 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47 5.00
105 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45 5.00
106 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42 5.00
107 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4 5.00
108 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
109 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33 5.00
110 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31 5.00
111 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3 5.00
112 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
113 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 5.00
114 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 5.00
115 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 5.00
116 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2 5.00
117 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 5.00
118 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
119 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19 5.00
120 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19 5.00
121 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
122 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15 5.00
123 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12 5.00
124 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
125 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06 5.00
126 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04 5.00
127 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 5.00
128 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01 5.00
129 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99 5.00
130 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98 5.00
131 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97 5.00
132 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96 5.00
133 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96 5.00
134 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93 5.00
135 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88 5.00
136 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87 5.00
137 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86 5.00
138 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85 5.00
139 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
140 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
141 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
142 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78 5.00
143 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77 5.00
144 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
145 INT344974 Lpar1 Regulation of Gene_expression of Mag 1 0.25 0.98 0.76 5.00
146 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75 5.00
147 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75 5.00
148 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73 5.00
149 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.68 0.71 5.00
150 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68 5.00
151 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66 5.00
152 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66 5.00
153 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65 5.00
154 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65 5.00
155 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65 5.00
156 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64 5.00
157 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64 5.00
158 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64 5.00
159 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63 5.00
160 INT266065 Positive_regulation of Binding of Ceacam3 and PAG1 1 0.03 1.44 0.63 5.00
161 INT266062 Binding of Ceacam3 and PAG1 1 0.02 1.44 0.63 5.00
162 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62 5.00
163 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62 5.00
164 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61 5.00
165 INT281132 Binding of Ccr3 and Cxcl10 1 0.00 0.25 0.6 5.00
166 INT213727 Ngf Regulation of Gene_expression of Fos 1 0.21 0.27 0.58 5.00
167 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58 5.00
168 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57 5.00
169 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 5.00
170 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56 5.00
171 INT333967 Binding of Osm and Sgp158 1 0.00 0.92 0.56 5.00
172 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55 5.00
173 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54 5.00
174 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54 5.00
175 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54 5.00
176 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54 5.00
177 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54 5.00
178 INT249499 Ephb1 Positive_regulation of Efnb2 1 0.04 0.95 0.54 5.00
179 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54 5.00
180 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53 5.00
181 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52 5.00
182 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52 5.00
183 INT249536 Binding of EPHA1 and Efnb2 1 0.02 0.28 0.52 5.00
184 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51 5.00
185 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51 5.00
186 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51 5.00
187 INT205733 Gphn Regulation of Gene_expression of Gabrd 1 0.03 0.18 0.51 5.00
188 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5 5.00
189 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49 5.00
190 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49 5.00
191 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48 5.00
192 INT217760 Il1f5 Positive_regulation of Gene_expression of Cpox 1 0.00 0.27 0.47 5.00
193 INT217759 Il1f5 Positive_regulation of Cpox 1 0.00 0.27 0.47 5.00
194 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46 5.00
195 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46 5.00
196 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46 5.00
197 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46 5.00
198 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46 5.00
199 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46 5.00
200 INT354235 Aif1 Regulation of P2ry12 1 0.20 0.49 0.45 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for hyperexcitability. They are ordered first by their pain relevance and then by number of times they were reported in hyperexcitability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT81207 Positive_regulation of Lth1 10 0.35 5.22 9.81 100.00
2 INT81208 Negative_regulation of Positive_regulation of Lth1 5 0.28 1.01 2.78 100.00
3 INT16025 Gene_expression of Lth1 6 0.40 1.89 2.5 100.00
4 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 100.00
5 INT81209 Negative_regulation of Lth1 3 0.28 0.97 1.94 100.00
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
7 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 100.00
8 INT123170 Negative_regulation of Gene_expression of Lth1 1 0.09 0.39 0.41 100.00
9 INT123169 Localization of Lth1 1 0.14 0.38 0.4 100.00
10 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 100.00
11 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 100.00
12 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 100.00
13 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57 100.00
14 INT148864 Localization of DRGX 11 0.17 7.67 8.36 100.00
15 INT81226 Gene_expression of Adk 9 0.64 9.28 4.81 100.00
16 INT91043 Regulation of NDRG1 7 0.25 2.66 1.65 100.00
17 INT226597 Regulation of Localization of DRGX 1 0.08 0.32 0.21 100.00
18 INT152352 Negative_regulation of Localization of DRGX 2 0.07 0.87 2.14 100.00
19 INT198059 Positive_regulation of CACNA1I 1 0.34 2.46 1.15 100.00
20 INT319919 Localization of SCN9A 1 0.51 0.31 0.92 100.00
21 INT319920 Negative_regulation of Localization of SCN9A 1 0.29 0.31 0.92 100.00
22 INT222727 Positive_regulation of RANGAP1 2 0.41 1.62 0.83 99.98
23 INT95167 Positive_regulation of DRGX 33 0.22 26.72 21.04 99.96
24 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 99.96
25 INT82882 Localization of Ccl2 61 0.80 41.96 28 99.96
26 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57 99.96
27 INT9039 Negative_regulation of Htr1a 69 0.57 9.56 41.84 99.96
28 INT12369 Negative_regulation of Htr3a 28 0.59 8.78 12.62 99.96
29 INT247619 Regulation of Positive_regulation of DRGX 1 0.03 1 0.97 99.96
30 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.92
31 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66 99.92
32 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 99.92
33 INT115270 Positive_regulation of P2rx6 9 0.48 6.37 5.06 99.90
34 INT144051 Positive_regulation of Gene_expression of PTGER1 11 0.12 4.46 3.97 99.90
35 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.84
36 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.80
37 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 99.76
38 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.68
39 INT94199 Regulation of DRGX 9 0.07 8.31 10.39 99.68
40 INT27018 Gene_expression of PTGER1 68 0.75 31.76 20.12 99.66
41 INT94563 Gene_expression of H2-Q10 7 0.42 7 0.88 99.64
42 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27 99.60
43 INT119498 Positive_regulation of Pde6b 11 0.43 18.75 4.22 99.60
44 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 99.58
45 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 99.52
46 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66 99.52
47 INT105866 Negative_regulation of Positive_regulation of PRKG1 3 0.12 0.98 0.64 99.52
48 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67 99.52
49 INT23886 Positive_regulation of Gene_expression of NA 15 0.40 3.69 3.59 99.52
50 INT256286 Negative_regulation of Gene_expression of Ephb1 1 0.43 3.36 2.78 99.48
51 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72 99.48
52 INT259774 Negative_regulation of Positive_regulation of P2ry1 1 0.33 1.11 0.54 99.48
53 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25 99.46
54 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 99.44
55 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32 99.44
56 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.44
57 INT339304 Negative_regulation of Gene_expression of Kcnj12 1 0.04 2.05 1.39 99.44
58 INT81314 Regulation of Gene_expression of NA 10 0.27 4.53 2.45 99.44
59 INT50535 Gene_expression of CA3 25 0.51 9.25 2.89 99.44
60 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4 99.40
61 INT149518 Regulation of Gene_expression of NAV1 7 0.62 6.73 9.62 99.40
62 INT51694 Negative_regulation of Positive_regulation of Es2 2 0.37 0.67 0.77 99.38
63 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 99.34
64 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 99.28
65 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08 99.28
66 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38 99.26
67 INT81210 Positive_regulation of PRKG1 71 0.70 26.83 19.89 99.24
68 INT48035 Positive_regulation of NT5C2 5 0.67 2.42 1.91 99.24
69 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.24
70 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 99.22
71 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 99.20
72 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 99.20
73 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 99.20
74 INT103496 Gene_expression of Vps52 3 0.39 3.22 1.78 99.12
75 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.04
76 INT12726 Gene_expression of Rtcd1 17 0.32 2.55 4.76 99.04
77 INT116707 Positive_regulation of Mapk4 8 0.21 9.83 7.96 99.00
78 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76 99.00
79 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95 98.96
80 INT96140 Gene_expression of Gimap1 3 0.22 12.87 28.9 98.96
81 INT19078 Binding of Ngf 78 0.48 31.03 44.33 98.92
82 INT1148 Positive_regulation of ecs 38 0.48 25.27 13.1 98.88
83 INT195521 Regulation of Grm2 2 0.07 0.51 0.62 98.88
84 INT102429 Negative_regulation of Gene_expression of Nav1 19 0.59 20.09 28.09 98.84
85 INT169873 Gene_expression of Kcnt1 1 0.07 1.21 1.19 98.84
86 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13 98.84
87 INT198058 Binding of CACNA1I 1 0.16 1.35 0.71 98.80
88 INT76434 Negative_regulation of PRKG1 25 0.58 10.36 10.81 98.76
89 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01 98.76
90 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 98.76
91 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 98.76
92 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19 98.76
93 INT14439 Regulation of GAL 12 0.61 2.25 4.02 98.68
94 INT66394 Regulation of Pdc 6 0.32 1.27 3.99 98.68
95 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 98.64
96 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13 98.64
97 INT165182 Gene_expression of P2ry12 4 0.65 4.29 4.08 98.64
98 INT145971 Localization of Nav1 20 0.81 10.3 18.11 98.60
99 INT76433 Regulation of PRKG1 13 0.34 4.27 4.57 98.60
100 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 98.56
101 INT131892 Localization of Kcna6 28 0.69 5.09 4.53 98.56
102 INT131895 Regulation of Localization of Kcna6 1 0.38 1.03 0.46 98.56
103 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 98.56
104 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2 98.52
105 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8 98.52
106 INT154773 Regulation of Accn3 7 0.62 7.09 6.63 98.52
107 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86 98.48
108 INT65832 Positive_regulation of PIRT 4 0.07 0.83 1.42 98.48
109 INT11705 Positive_regulation of Es2 4 0.60 1.86 2.79 98.46
110 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54 98.40
111 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06 98.40
112 INT126115 Binding of Kcna7 1 0.10 1.51 0.4 98.40
113 INT131899 Gene_expression of Kcnj12 3 0.07 11.85 8.35 98.36
114 INT40478 Negative_regulation of NCOR2 23 0.48 12.77 14.56 98.36
115 INT162305 Positive_regulation of Gene_expression of Mapk4 1 0.21 1.69 2.01 98.34
116 INT266567 Regulation of Localization of Nav1 1 0.21 1.89 0.83 98.32
117 INT287 Localization of Cck 518 0.81 86.84 364.04 98.24
118 INT150285 Positive_regulation of Efnb1 6 0.29 10.22 11.44 98.24
119 INT145921 Localization of CCL21 4 0.73 2.41 1.58 98.24
120 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 98.24
121 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59 98.22
122 INT109015 Positive_regulation of Positive_regulation of PRKG1 5 0.38 2.04 1.87 98.22
123 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 98.20
124 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 98.20
125 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 51 0.53 15.32 5.86 98.20
126 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49 98.20
127 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 98.16
128 INT162307 Gene_expression of Mapk4 2 0.23 2.89 3.44 98.14
129 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 98.12
130 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63 98.12
131 INT103236 Positive_regulation of Positive_regulation of P2ry1 5 0.54 2.39 1.92 98.12
132 INT92734 Binding of Ephb1 5 0.37 3.86 7.02 98.08
133 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95 98.08
134 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 98.00
135 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 97.96
136 INT160134 Regulation of Hcn1 2 0.38 0.54 0.7 97.96
137 INT4189 Negative_regulation of Localization of PGE 3 0.37 0.6 1.62 97.88
138 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 97.84
139 INT153220 Negative_regulation of Positive_regulation of Rela 1 0.09 0.31 1.31 97.80
140 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 97.72
141 INT271481 Regulation of Regulation of Gad2 1 0.21 0.59 0.65 97.68
142 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 97.64
143 INT4190 Localization of PGE 19 0.60 4.97 7.9 97.56
144 INT164558 Binding of PERP 3 0.14 1.55 1.67 97.56
145 INT70705 Regulation of Regulation of Gabrg1 3 0.15 0.29 1.69 97.52
146 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34 97.44
147 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76 97.44
148 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14 97.44
149 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 97.42
150 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51 97.36
151 INT73322 Transcription of Scn10a 8 0.69 5.35 4.99 97.32
152 INT179213 Gene_expression of Aqp3 10 0.63 5.13 0.77 97.32
153 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34 97.32
154 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54 97.32
155 INT89714 Regulation of Transcription of Scn10a 3 0.60 2.43 1.9 97.32
156 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 97.32
157 INT167311 Gene_expression of Aqp5 8 0.61 1.77 2.75 97.32
158 INT89715 Regulation of Scn10a 3 0.60 1.81 1.61 97.32
159 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6 97.32
160 INT247883 Negative_regulation of Gene_expression of Aqp3 1 0.34 0.56 0.05 97.32
161 INT28314 Negative_regulation of Gene_expression of Gabrg1 29 0.44 12.56 13.8 97.28
162 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 97.28
163 INT165514 Regulation of Gad2 7 0.45 3.15 2.76 97.28
164 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 97.24
165 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 97.20
166 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72 97.20
167 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 97.16
168 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 97.16
169 INT142274 Gene_expression of TRPM2 7 0.78 2.29 1.31 97.12
170 INT339307 Positive_regulation of Gene_expression of Kcnj12 1 0.04 3.6 2.47 97.12
171 INT142276 Positive_regulation of Gene_expression of TRPM2 1 0.70 1.26 0.74 97.12
172 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17 97.12
173 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74 97.12
174 INT3877 Negative_regulation of MUC7 30 0.57 1.62 12.89 97.08
175 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 97.04
176 INT19511 Localization of Il6 212 0.81 118.17 67.67 97.04
177 INT333963 Localization of Il6r 1 0.10 0.75 0.83 97.04
178 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 97.00
179 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 97.00
180 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46 97.00
181 INT233423 Negative_regulation of Kcnq2 1 0.32 0.16 0.37 97.00
182 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 96.96
183 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 96.92
184 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 96.92
185 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13 96.92
186 INT27627 Binding of Rac1 41 0.41 22.88 13.68 96.92
187 INT291558 Protein_catabolism of NMS 1 0.39 0.39 0.12 96.92
188 INT16226 Negative_regulation of Rit2 10 0.59 1.42 2.1 96.80
189 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 96.80
190 INT21611 Negative_regulation of RASGRP1 20 0.35 11.76 2.15 96.76
191 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 96.76
192 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 96.72
193 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33 96.72
194 INT8087 Regulation of Localization of Npy 16 0.45 2.41 6.81 96.72
195 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 96.68
196 INT142941 Negative_regulation of Scn11a 14 0.43 12.2 13.38 96.64
197 INT259775 Positive_regulation of Positive_regulation of Rs1 1 0.00 1.07 0.53 96.64
198 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 96.64
199 INT151436 Regulation of Ccr2 4 0.44 2.81 2.82 96.64
200 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5 96.56
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