P:intrathecal

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pChart

Pain Term
Category Anatomy
Synonyms None
Pain Specific No
Documents 6801
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for intrathecal. They are ordered first by their pain relevance and then by number of times they were reported for intrathecal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78 100.00
2 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78 100.00
3 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77 100.00
4 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3 100.00
5 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 100.00
6 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25 100.00
7 INT144608 Mapk7 Negative_regulation of Gene_expression of Fos 2 0.65 0.43 0.42 100.00
8 INT61345 Iapp Regulation of GAL 2 0.08 0.35 0.41 100.00
9 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63 100.00
10 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83 100.00
11 INT61343 Iapp Regulation of Gal 1 0.09 0.17 0.15 100.00
12 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72 100.00
13 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92 99.98
14 INT154989 Phax Positive_regulation of Positive_regulation of Ephb1 1 0.22 0.92 0.69 99.98
15 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41 99.98
16 INT120323 Slc5a7 Negative_regulation of Flvcr2 1 0.02 0.43 1.1 99.98
17 INT172508 Binding of Cnnm1 and Mir343 1 0.01 0.15 1.08 99.98
18 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58 99.98
19 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42 99.98
20 INT127076 Gene_expression of Bdnf Positive_regulation of Gene_expression of IER3 1 0.03 0.26 0.42 99.98
21 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86 99.92
22 INT104016 RPGR Positive_regulation of Gene_expression of FOS 1 0.16 0 0.43 99.90
23 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79 99.84
24 INT287744 Lpar3 Positive_regulation of Positive_regulation of Lpar1 1 0.46 0.39 0.58 99.84
25 INT287753 Lpar3 Positive_regulation of Gene_expression of Lpar1 1 0.46 0.39 0.58 99.84
26 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61 99.84
27 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57 99.84
28 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42 99.72
29 INT122832 AP1B1 Negative_regulation of Gene_expression of FLII 1 0.01 0 0.47 99.68
30 INT120324 Hc3 Negative_regulation of Flvcr2 1 0.06 0.42 1.09 99.64
31 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86 99.56
32 INT127078 Bdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42 99.54
33 INT79365 Pnoc Negative_regulation of Oprl1 2 0.41 0.16 1.72 99.48
34 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93 99.40
35 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74 99.28
36 INT172515 Mir343 Positive_regulation of Positive_regulation of ECT 1 0.03 0.09 0.42 99.24
37 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53 99.16
38 INT22109 Positive_regulation of Pomc Positive_regulation of Penk 1 0.35 0 0.99 99.16
39 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1 99.12
40 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49 99.08
41 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46 99.08
42 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74 99.02
43 INT149006 RPL7AP5 Negative_regulation of Phosphorylation of Ephb1 1 0.00 0.22 0.45 98.98
44 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 98.98
45 INT149005 RPL7AP5 Negative_regulation of Ephb1 1 0.00 0.21 0.44 98.98
46 INT178821 TNF Negative_regulation of Il18 1 0.29 0.64 0.08 98.94
47 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87 98.72
48 INT108073 Pnoc Negative_regulation of Gene_expression of Fos 1 0.32 0.25 0.76 98.56
49 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 98.44
50 INT95783 Negative_regulation of Dnajc13 Positive_regulation of P9Ehs1 1 0.00 0 0.56 98.42
51 INT62018 CSF2 Regulation of ACOT1 1 0.12 0.47 1.21 98.28
52 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21 98.28
53 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 98.24
54 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07 98.22
55 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12 98.12
56 INT287752 Dmbx1 Positive_regulation of Positive_regulation of Lpar1 1 0.41 0.39 0.58 98.08
57 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16 98.08
58 INT95782 Dnajc13 Positive_regulation of P9Ehs1 1 0.01 0 0.56 98.04
59 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55 98.04
60 INT31861 Cd79b Regulation of Sst 1 0.49 0.31 0.56 98.04
61 INT31862 Pdyn Regulation of Sst 1 0.45 0.31 0.56 98.04
62 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61 97.92
63 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32 97.90
64 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77 97.84
65 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77 97.84
66 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9 97.76
67 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9 97.76
68 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32 97.74
69 INT153330 Binding of PTGER3 and Cm9 1 0.36 0.15 0.48 97.64
70 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54 97.52
71 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98 97.44
72 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61 97.36
73 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58 97.36
74 INT77377 Binding of Cnr1 and Fbln5 1 0.02 0 0.48 97.28
75 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87 97.20
76 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68 97.14
77 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66 97.14
78 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9 97.04
79 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42 96.96
80 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 96.84
81 INT172511 Mir343 Positive_regulation of ECT 1 0.04 0.08 0.6 96.80
82 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 96.64
83 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02 96.56
84 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63 96.44
85 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89 96.44
86 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91 96.40
87 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84 96.40
88 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98 96.32
89 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46 96.16
90 INT128515 Binding of PNOC and Pnoc 1 0.12 0.38 1.14 96.16
91 INT336388 Binding of IL2 and ALPK1 1 0.06 0.73 0.05 96.08
92 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93 95.88
93 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23 95.68
94 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71 95.64
95 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71 95.64
96 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19 95.56
97 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2 95.56
98 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89 95.44
99 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14 95.44
100 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73 95.24
101 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83 95.04
102 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88 94.96
103 INT124353 Prkcg Positive_regulation of Positive_regulation of Gorasp2 1 0.02 1.19 0.73 94.88
104 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 94.64
105 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75 94.64
106 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97 94.64
107 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96 94.60
108 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06 94.48
109 INT128512 Regulation of Pnoc Regulation of Adarb1 1 0.01 0.46 1.58 94.48
110 INT128513 Pnoc Regulation of Adarb1 1 0.01 0.92 3.14 94.08
111 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32 94.00
112 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46 93.92
113 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76 93.60
114 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01 93.44
115 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1 93.44
116 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1 93.44
117 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 93.28
118 INT57956 LOC365260 Negative_regulation of Cck 1 0.11 0 1.3 93.12
119 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46 93.08
120 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29 93.00
121 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88 92.80
122 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61 92.80
123 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61 92.80
124 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29 92.72
125 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58 92.56
126 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14 92.48
127 INT32241 Pomc Negative_regulation of Pomc Positive_regulation of Penk 1 0.23 0 0.63 92.48
128 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55 92.40
129 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63 92.24
130 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67 92.24
131 INT155462 Tnfrsf1a Positive_regulation of Nfkb1 Regulation of Gene_expression of Il6 1 0.20 1.17 0.67 92.24
132 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91 92.16
133 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75 92.00
134 INT157297 Npy Regulation of Npy1r 1 0.18 0.19 0.82 92.00
135 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63 92.00
136 INT113610 Binding of Nsf and Grip2 1 0.24 0.6 0.63 92.00
137 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31 91.96
138 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14 91.96
139 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 91.76
140 INT249499 Ephb1 Positive_regulation of Efnb2 1 0.04 0.95 0.54 91.64
141 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9 91.60
142 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37 91.60
143 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 91.56
144 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64 91.36
145 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63 91.36
146 INT81520 Binding of PNOC and Oprl1 1 0.24 0.1 0.75 91.20
147 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88 91.12
148 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31 91.12
149 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17 90.96
150 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36 90.96
151 INT213727 Ngf Regulation of Gene_expression of Fos 1 0.21 0.27 0.58 90.84
152 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2 90.80
153 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2 90.80
154 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34 90.72
155 INT349850 Gfra1 Negative_regulation of Adcyap1r1 1 0.15 0.36 0.15 90.72
156 INT349851 Gfra3 Negative_regulation of Adcyap1r1 1 0.28 0.31 0.15 90.72
157 INT349849 Gfra2 Negative_regulation of Adcyap1r1 1 0.33 0.31 0.15 90.72
158 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55 90.64
159 INT281649 Negative_regulation of Binding of Calca and Trpv1 1 0.13 0.67 0.54 90.64
160 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36 90.56
161 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 90.40
162 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 90.36
163 INT76378 Binding of Cit and Flvcr2 1 0.09 0.17 1.15 90.24
164 INT76377 Regulation of Binding of Cit and Flvcr2 1 0.07 0.09 0.57 90.24
165 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2 90.08
166 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2 90.08
167 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2 90.08
168 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 89.84
169 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75 89.80
170 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79 89.80
171 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 89.76
172 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55 89.60
173 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 89.52
174 INT127254 Binding of Gpr176 and Npbwr1 1 0.02 0.49 0.72 89.44
175 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6 89.24
176 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35 89.24
177 INT349861 Gfra1 Negative_regulation of Ntrk1 1 0.01 0.36 0.15 89.20
178 INT349859 Gfra2 Negative_regulation of Ntrk1 1 0.02 0.3 0.15 89.20
179 INT349862 Gfra3 Negative_regulation of Ntrk1 1 0.02 0.3 0.15 89.20
180 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22 89.08
181 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 0.01 0 1.58 89.00
182 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63 88.88
183 INT88971 Binding of Sult4a1 and Atrn 1 0.02 0.54 1.03 88.76
184 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15 88.72
185 INT349852 Gfra2 Negative_regulation of Ntrk1 1 0.27 0.3 0.15 88.72
186 INT349856 Gfra3 Negative_regulation of Ntrk1 1 0.23 0.3 0.15 88.72
187 INT349854 Gfra1 Negative_regulation of Ntrk1 1 0.12 0.36 0.15 88.72
188 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19 88.40
189 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98 88.24
190 INT118157 Binding of Prkca and Prkcz Positive_regulation of Binding of Prkca Prkcz 1 0.02 0.58 1.55 88.24
191 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2 88.16
192 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66 88.08
193 INT349857 Gfra2 Negative_regulation of Gfra3 1 0.20 0.3 0.15 88.00
194 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82 87.88
195 INT325807 CXCL13 Positive_regulation of CISH 1 0.16 3.65 0.89 87.68
196 INT118159 Binding of Prkca and Prkcz Positive_regulation of Prkcz 1 0.02 0.58 1.54 87.48
197 INT118160 Binding of Prkca and Prkcz Positive_regulation of Prkca 1 0.11 0.58 1.54 87.48
198 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92 87.20
199 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99 87.20
200 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 87.16

Single Events

The table below shows the top 200 pain related interactions that have been reported for intrathecal. They are ordered first by their pain relevance and then by number of times they were reported in intrathecal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 100.00
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
3 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
4 INT12820 Gene_expression of LOC683257 3 0.35 14.85 5.27 100.00
5 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 100.00
6 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
7 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
8 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
9 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
10 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 100.00
11 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
12 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
13 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 100.00
14 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
15 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 100.00
16 INT66416 Regulation of Pnoc 66 0.61 17.32 68.91 100.00
17 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
18 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 100.00
19 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68 100.00
20 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
21 INT1004 Regulation of Sst 140 0.62 18.52 94.84 100.00
22 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 100.00
23 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
24 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 100.00
25 INT5040 Regulation of Gal 42 0.60 12.72 21.18 100.00
26 INT8824 Regulation of Vip 95 0.62 15.7 43.63 100.00
27 INT24655 Negative_regulation of Neo1 4 0.35 0.32 2.42 100.00
28 INT55637 Negative_regulation of Upb1 1 0.22 0.32 0.94 100.00
29 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 100.00
30 INT144607 Positive_regulation of Gene_expression of Mapk7 8 0.61 2.09 2.82 100.00
31 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 100.00
32 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 100.00
33 INT5156 Regulation of ZC3H12D 7 0.27 2.64 5.53 100.00
34 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
35 INT92572 Gene_expression of Mapk7 17 0.78 3.71 4.76 100.00
36 INT2976 Regulation of Bche 29 0.45 8.56 9.42 100.00
37 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
38 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14 100.00
39 INT236842 Positive_regulation of Gene_expression of CXCL13 6 0.32 3.91 2.55 100.00
40 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
41 INT64440 Gene_expression of Pnoc 66 0.78 13.61 41.76 100.00
42 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 100.00
43 INT451 Regulation of Oxt 142 0.62 22.07 69.42 100.00
44 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19 100.00
45 INT128941 Gene_expression of Mir343 2 0.42 0.46 2.27 100.00
46 INT156427 Localization of FOXC1 2 0.73 1.36 1.07 100.00
47 INT7029 Regulation of Pdyn 51 0.61 12.89 40.34 100.00
48 INT7039 Regulation of Nkx1-1 22 0.44 10.51 20.89 100.00
49 INT9988 Regulation of Hrh1 22 0.46 12.87 22.13 100.00
50 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 100.00
51 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 100.00
52 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52 100.00
53 INT5186 Regulation of Ifng 11 0.45 8.78 5.9 100.00
54 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 100.00
55 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 100.00
56 INT9167 Binding of Adora1 6 0.40 0.53 6.9 100.00
57 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84 100.00
58 INT15796 Regulation of IL2 66 0.61 25.43 20.62 100.00
59 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95 100.00
60 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31 100.00
61 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 100.00
62 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62 100.00
63 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 100.00
64 INT49538 Binding of Gria1 22 0.47 2.66 13.35 100.00
65 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95 100.00
66 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37 100.00
67 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 100.00
68 INT148899 Regulation of Sort1 2 0.50 2.72 3.46 100.00
69 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
70 INT14506 Regulation of Sst 46 0.62 15.02 22.66 100.00
71 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 100.00
72 INT14439 Regulation of GAL 12 0.61 2.25 4.02 100.00
73 INT21650 Regulation of OXTR 29 0.61 5.99 4.91 100.00
74 INT1120 Gene_expression of C3 33 0.67 22.86 7.56 100.00
75 INT83505 Binding of AP-5 2 0.10 0.35 1.19 100.00
76 INT53007 Regulation of Gene_expression of Fosl1 6 0.27 1.28 5.06 100.00
77 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 100.00
78 INT615 Regulation of Alb 66 0.62 33.43 15.33 100.00
79 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 100.00
80 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 100.00
81 INT78797 Regulation of Tmem132a 8 0.45 3.61 12.73 100.00
82 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 100.00
83 INT73169 Localization of Mir343 2 0.46 0 0.65 100.00
84 INT21463 Binding of Epha1 5 0.46 1.44 3.25 100.00
85 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43 100.00
86 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 100.00
87 INT187293 Negative_regulation of Gene_expression of CD79A 3 0.08 0.81 0.51 100.00
88 INT105938 Negative_regulation of Gene_expression of Igh-6 7 0.30 4.7 1.36 100.00
89 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46 100.00
90 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02 100.00
91 INT259185 Regulation of CFM2 1 0.04 1.11 1.03 100.00
92 INT92811 Regulation of RPL7AP5 1 0.24 0.33 0.51 100.00
93 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41 100.00
94 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88 100.00
95 INT295469 Localization of Tlr4 3 0.75 2.22 1.88 100.00
96 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62 100.00
97 INT89281 Negative_regulation of Gene_expression of HLA-DRB1 10 0.30 5.9 2.55 100.00
98 INT22270 Regulation of IGKV1-5 13 0.39 3.56 3.54 100.00
99 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
100 INT8393 Regulation of Gene_expression of Nts 11 0.48 1.02 6.83 100.00
101 INT60546 Regulation of Iapp 2 0.45 0.36 0.56 100.00
102 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
103 INT26218 Gene_expression of Gt(pU21)50Imeg 3 0.02 0.26 4.63 100.00
104 INT190644 Regulation of Negative_regulation of Mdk 6 0.26 2.49 1.98 100.00
105 INT62861 Regulation of Gria2 45 0.60 13.35 16.07 100.00
106 INT47894 Regulation of Npy1r 5 0.33 3.08 4.27 100.00
107 INT21464 Positive_regulation of Binding of Epha1 2 0.58 0.44 1.06 100.00
108 INT143092 Negative_regulation of Negative_regulation of Grin2b 1 0.27 0.33 0.83 100.00
109 INT326192 Negative_regulation of Binding of Ntrk2 1 0.10 1 1.47 100.00
110 INT50633 Regulation of Gene_expression of Glul 12 0.60 1.64 6.59 100.00
111 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98 100.00
112 INT129096 Regulation of Scn11a 1 0.05 0.77 1.35 100.00
113 INT1616 Regulation of Gad1 46 0.61 10.2 28.64 100.00
114 INT16194 Binding of CNR1 82 0.48 20.75 39.59 100.00
115 INT85075 Phosphorylation of Mdk 22 0.61 10.29 5.55 100.00
116 INT131572 Negative_regulation of Phosphorylation of Mdk 4 0.15 1.67 1.71 100.00
117 INT25393 Positive_regulation of Localization of Ptger2 19 0.32 9.69 3.23 100.00
118 INT9197 Binding of PTGS1 44 0.48 18.48 16.26 100.00
119 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 100.00
120 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79 100.00
121 INT10808 Negative_regulation of Negative_regulation of Fos 3 0.57 1.08 3.92 100.00
122 INT84473 Gene_expression of SARDH 5 0.77 1.21 3.37 100.00
123 INT124921 Negative_regulation of Negative_regulation of Slc1a1 3 0.56 0.67 3.36 100.00
124 INT9229 Negative_regulation of Gene_expression of Htr3a 5 0.41 0.83 3.13 100.00
125 INT124922 Negative_regulation of Negative_regulation of Slc1a2 2 0.35 0.07 2.79 100.00
126 INT31451 Negative_regulation of Gene_expression of Adra2a 4 0.43 1.03 2.72 100.00
127 INT265529 Regulation of Phosphorylation of Myrip 1 0.00 0.54 1.22 100.00
128 INT50409 Regulation of Localization of Fos 3 0.44 0.2 1.07 100.00
129 INT112082 Regulation of Vsig2 13 0.40 1.89 0.98 100.00
130 INT47841 Regulation of Cpa6 1 0.03 0 0.86 100.00
131 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.98
132 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.98
133 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 99.98
134 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07 99.98
135 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.98
136 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.98
137 INT14726 Gene_expression of Mag 8 0.42 8.23 5 99.98
138 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.98
139 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.98
140 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72 99.98
141 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.98
142 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 99.98
143 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 99.98
144 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 99.98
145 INT14867 Gene_expression of Igh-6 47 0.67 30.05 11.75 99.98
146 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 99.98
147 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 99.98
148 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 99.98
149 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 99.98
150 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 99.98
151 INT2366 Binding of Cck 192 0.48 30.64 163.46 99.98
152 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06 99.98
153 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.98
154 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.98
155 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 99.98
156 INT24141 Negative_regulation of Apcs 24 0.59 16.82 8.29 99.98
157 INT24965 Gene_expression of Igkv4-59 4 0.33 0.26 5.8 99.98
158 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 99.98
159 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 99.98
160 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.98
161 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.98
162 INT15312 Negative_regulation of Gene_expression of Gal 8 0.57 2.77 4.55 99.98
163 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.98
164 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.98
165 INT25915 Negative_regulation of RPL7AP5 9 0.38 3.56 8.5 99.98
166 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 99.98
167 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 99.98
168 INT53482 Gene_expression of ITIH4 75 0.77 58.87 26.05 99.98
169 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 99.98
170 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 99.98
171 INT1139 Gene_expression of IgG-2a 35 0.65 19.19 12 99.98
172 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73 99.98
173 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.98
174 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 99.98
175 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 99.98
176 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21 99.98
177 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.98
178 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.98
179 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 99.98
180 INT45914 Gene_expression of Apcs 22 0.65 24.25 8.48 99.98
181 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 99.98
182 INT135087 Negative_regulation of Gene_expression of Phax 5 0.17 4.39 4.1 99.98
183 INT84057 Positive_regulation of Gene_expression of ITIH4 12 0.50 10.5 4.92 99.98
184 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 99.98
185 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 99.98
186 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 99.98
187 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 99.98
188 INT5586 Binding of Fos 47 0.48 12.7 21.33 99.98
189 INT1376 Binding of Trh 121 0.48 20 69.86 99.98
190 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35 99.98
191 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14 99.98
192 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 99.98
193 INT28774 Localization of LAMC2 6 0.73 3.2 0.76 99.98
194 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05 99.98
195 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22 99.98
196 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 99.98
197 INT254145 Gene_expression of Ppap2a 9 0.10 2.66 4.33 99.98
198 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29 99.98
199 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63 99.98
200 INT10763 Localization of IL2 157 0.80 81.11 33.21 99.98
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