P:isoflurane

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 4758
Hot Single Events 200
Hot Interactions 29

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for isoflurane. They are ordered first by their pain relevance and then by number of times they were reported for isoflurane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17774 Alb Negative_regulation of Dnase1 1 0.02 0 0.46 99.56
2 INT121081 Negative_regulation of NOS1 Negative_regulation of Slep1 1 0.00 0 0.52 99.56
3 INT62849 TUBE1 Positive_regulation of Rmp1 1 0.02 0 0.65 99.12
4 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94 98.96
5 INT310564 Positive_regulation of Ephb1 Regulation of Stat3 1 0.03 0.17 0.08 98.80
6 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66 97.36
7 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79 97.20
8 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58 96.88
9 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35 94.48
10 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34 94.48
11 INT153879 Gast Positive_regulation of Positive_regulation of TRPV1 1 0.09 0.35 0.76 94.24
12 INT149191 TNF Positive_regulation of Gene_expression of ESAM 1 0.47 0.68 0.33 94.00
13 INT151558 ERLEC1 Regulation of Atp2a1 1 0.00 0.64 0.53 93.96
14 INT151557 NARG2 Regulation of Atp2a1 1 0.01 0.64 0.53 93.96
15 INT151552 NARG2 Regulation of DNAH8 1 0.00 0.64 0.5 93.96
16 INT151553 ERLEC1 Regulation of DNAH8 1 0.00 0.64 0.5 93.96
17 INT284564 Binding of Itgax and Mthfd1 1 0.08 0.09 0.05 93.20
18 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23 91.04
19 INT326473 Positive_regulation of PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.41 90.36
20 INT326470 PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.4 90.04
21 INT131357 Agtr2 Regulation of Ren 1 0.04 0.88 0.27 89.12
22 INT332411 Akt1 Positive_regulation of Phosphorylation of Met 1 0.31 0.05 0.04 86.88
23 INT332410 Mapk1 Positive_regulation of Phosphorylation of Met 1 0.32 0.05 0.04 86.24
24 INT134324 Gh Regulation of Gene_expression of F8a 1 0.07 0 0.33 84.48
25 INT149730 LOC500077 Regulation of Cebpz 1 0.34 1.23 0.77 84.24
26 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4 84.16
27 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16 81.84
28 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16 81.84
29 INT59845 Negative_regulation of IFNA1 Positive_regulation of Gpi1 1 0.09 0 0.37 80.32
30 INT59844 IFNA1 Positive_regulation of Gpi1 1 0.10 0 0.37 79.64
31 INT59843 IFNA1 Positive_regulation of IFNA1 Positive_regulation of Gpi1 1 0.05 0 0.37 79.64
32 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49 79.40
33 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2 79.40
34 INT149929 Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.12 0 0.61 78.56
35 INT158466 FECH Negative_regulation of Fech 1 0.23 0.57 0.2 78.00
36 INT65946 Ins1 Positive_regulation of Atp2b4 1 0.20 0.46 0.25 76.96
37 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75 75.60
38 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 72.56
39 INT127206 Negative_regulation of Cftr Negative_regulation of Positive_regulation of Mcf2l 1 0.16 0.62 0.16 70.40
40 INT196584 Binding of Mapk14 and NeuN 1 0.02 0.39 0.27 70.32
41 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11 69.72
42 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62 69.68
43 INT239398 Atp7b Regulation of OAP 1 0.03 1.1 0.35 68.88
44 INT132897 Binding of ABCB1 and Slco1c1 1 0.03 0 0.2 65.92
45 INT313374 Cnr1 Regulation of Gene_expression of Cnr2 1 0.36 0 0.3 64.80
46 INT326472 AGXT Negative_regulation of PGAP1 1 0.00 0.05 0.39 63.60
47 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22 63.20
48 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22 62.56
49 INT245144 Binding of Hbb-ar and hIL 1 0.40 0.41 0.17 58.72
50 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24 57.28
51 INT22320 Binding of Cys1 and sch 1 0.02 0.45 0.15 56.32
52 INT315435 Negative_regulation of Binding of IGHG3 and SEMA4B 1 0.22 0.12 0.03 55.52
53 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 55.28
54 INT315437 Binding of IGHG3 and SEMA4B 1 0.19 0.12 0.03 55.24
55 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4 54.48
56 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4 54.48
57 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67 50.92
58 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 50.00
59 INT149193 TNF Positive_regulation of Gene_expression of NFKB2 1 0.11 0.07 0 50.00
60 INT149194 TNF Positive_regulation of NFKB2 1 0.16 0.05 0 50.00
61 INT70122 NAGLU Positive_regulation of Localization of Anpep 1 0.10 0 0 50.00
62 INT149189 Negative_regulation of TNF Positive_regulation of NFKB2 1 0.13 0.05 0 50.00
63 INT92824 AGT Regulation of Gene_expression of REN 1 0.05 0 0 50.00
64 INT149190 TNF Positive_regulation of Transcription of NFKB2 1 0.11 0.13 0 50.00
65 INT341294 DRG1 Positive_regulation of Atf3 1 0.01 0 0.1 48.08
66 INT350342 Tbp Positive_regulation of Ltp 1 0.25 0.48 0.64 46.32
67 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06 40.44
68 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31 39.92
69 INT297229 Binding of Kcnj8 and Abcc8 1 0.03 0 0.42 37.12
70 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14 35.92
71 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14 35.92
72 INT336924 Aggf1 Positive_regulation of Gopc 1 0.00 0 0 34.56
73 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22 34.24
74 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69 33.04
75 INT282664 Binding of Aif1 and Gfap 1 0.06 0 0.69 33.04
76 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09 32.88
77 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27 32.40
78 INT293125 Agt Regulation of Avp Regulation of Aqp2 1 0.04 0.36 0.14 32.40
79 INT293126 Agtr1a Regulation of Avp Regulation of Aqp2 1 0.03 0.36 0.14 32.40
80 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14 31.92
81 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14 31.92
82 INT298729 PROC Positive_regulation of Set 1 0.00 0.76 0.55 30.84
83 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08 28.84
84 INT244322 Negative_regulation of Binding of Csf2 and Tlr4 1 0.19 0 0.03 28.76
85 INT244321 Binding of Csf2 and Tlr4 1 0.17 0 0.03 28.20
86 INT336925 Aggf1 Positive_regulation of Mir341 1 0.00 0.8 0.21 27.36
87 INT340277 Tnfsf11 Positive_regulation of TRAP 1 0.03 0.76 0 25.80
88 INT340238 Tnfsf11 Positive_regulation of Gene_expression of Fig4 1 0.02 0.4 0 25.80
89 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14 22.80
90 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09 22.72
91 INT194264 Tnnc1 Regulation of Mb 1 0.00 0.16 0 22.04
92 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02 15.84
93 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93 15.76
94 INT308004 Rsph1 Positive_regulation of Mapk14 1 0.02 0.61 0.12 13.72
95 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 13.28
96 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8 10.72
97 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41 9.44
98 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56 6.56
99 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57 6.40
100 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 5.00
101 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
102 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
103 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 5.00
104 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
105 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
106 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 5.00
107 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
108 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
109 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
110 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01 5.00
111 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 5.00
112 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 5.00
113 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 5.00
114 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6 5.00
115 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6 5.00
116 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 5.00
117 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35 5.00
118 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 5.00
119 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 5.00
120 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19 5.00
121 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 5.00
122 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
123 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06 5.00
124 INT240658 Ngf Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.33 1.67 1.99 5.00
125 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96 5.00
126 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95 5.00
127 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89 5.00
128 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89 5.00
129 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88 5.00
130 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86 5.00
131 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86 5.00
132 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85 5.00
133 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 5.00
134 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83 5.00
135 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8 5.00
136 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 5.00
137 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76 5.00
138 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 5.00
139 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74 5.00
140 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71 5.00
141 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68 5.00
142 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 5.00
143 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61 5.00
144 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61 5.00
145 INT212287 ro Negative_regulation of Ltp 1 0.00 1.2 1.58 5.00
146 INT237286 Dlat Regulation of Prep 1 0.01 0 1.57 5.00
147 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55 5.00
148 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
149 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 5.00
150 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48 5.00
151 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48 5.00
152 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
153 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45 5.00
154 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43 5.00
155 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42 5.00
156 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41 5.00
157 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4 5.00
158 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4 5.00
159 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39 5.00
160 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38 5.00
161 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36 5.00
162 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 5.00
163 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26 5.00
164 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25 5.00
165 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23 5.00
166 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23 5.00
167 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 5.00
168 INT310066 Negative_regulation of Pain1 Positive_regulation of Faah 1 0.03 1.32 1.23 5.00
169 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23 5.00
170 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23 5.00
171 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22 5.00
172 INT310068 Pain1 Positive_regulation of Faah 1 0.03 1.3 1.22 5.00
173 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22 5.00
174 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21 5.00
175 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 5.00
176 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
177 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 5.00
178 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
179 INT206766 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Nkx1-1 1 0.01 0.22 1.16 5.00
180 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
181 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15 5.00
182 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 5.00
183 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 5.00
184 INT212280 Vsnl1 Negative_regulation of Ltp 1 0.00 0.72 1.11 5.00
185 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09 5.00
186 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08 5.00
187 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08 5.00
188 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08 5.00
189 INT212281 Vsnl1 Regulation of Ltp 1 0.00 1.32 1.07 5.00
190 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06 5.00
191 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05 5.00
192 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05 5.00
193 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04 5.00
194 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03 5.00
195 INT197241 Kars Regulation of Localization of Gabrg1 1 0.23 0 1.02 5.00
196 INT230594 Binding of Hrh1 and Hrh2 1 0.24 0.99 1.02 5.00
197 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01 5.00
198 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01 5.00
199 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01 5.00
200 INT250085 Coq7 Positive_regulation of Ltp 1 0.00 0.52 1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for isoflurane. They are ordered first by their pain relevance and then by number of times they were reported in isoflurane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2330 Regulation of CB 78 0.10 20.46 32.6 100.00
2 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 100.00
3 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95 100.00
4 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93 100.00
5 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
6 INT3301 Positive_regulation of Slc43a3 26 0.55 5.48 10.81 100.00
7 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 100.00
8 INT5592 Regulation of Regulation of Penk 36 0.62 4.37 24.02 100.00
9 INT15470 Regulation of CPP 42 0.48 26.1 18.25 100.00
10 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
11 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61 100.00
12 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
13 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94 100.00
14 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
15 INT17772 Regulation of Dnase1 1 0.48 0 0.63 100.00
16 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 100.00
17 INT81827 Positive_regulation of Kcnk2 7 0.70 0.42 1.79 100.00
18 INT3794 Regulation of CDNF 16 0.16 2.99 5.59 100.00
19 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
20 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
21 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
22 INT10299 Regulation of Localization of Fglu 1 0.01 0.37 1.03 100.00
23 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41 100.00
24 INT37621 Gene_expression of Des 6 0.65 2.17 2.48 100.00
25 INT605 Regulation of Acot1 61 0.62 10.7 26.34 100.00
26 INT145919 Regulation of KCNK3 5 0.62 0.09 1.22 100.00
27 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 100.00
28 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
29 INT166331 Localization of Kcna1 2 0.33 0.4 1.58 100.00
30 INT166333 Positive_regulation of Kcna1 3 0.21 1.11 1.81 100.00
31 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07 100.00
32 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08 100.00
33 INT102734 Gene_expression of Atp6v0a2 18 0.50 6.28 2.76 100.00
34 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48 100.00
35 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52 100.00
36 INT110075 Binding of FTH1 10 0.36 1.12 1.13 100.00
37 INT106083 Negative_regulation of Kcna1 4 0.21 0.92 1.92 100.00
38 INT166332 Positive_regulation of Negative_regulation of Kcna1 1 0.22 0 1.2 100.00
39 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28 100.00
40 INT71568 Regulation of Protein_catabolism of Map2 1 0.45 0.8 0.58 100.00
41 INT12444 Binding of Gabrd 26 0.48 4.7 11.23 100.00
42 INT120042 Regulation of Binding of Naa15 1 0.15 0.19 0.57 100.00
43 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
44 INT45824 Regulation of Positive_regulation of Abat 6 0.24 1.2 5.16 100.00
45 INT68667 Regulation of Fosl1 4 0.19 0.89 0.98 100.00
46 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97 100.00
47 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18 100.00
48 INT117358 Positive_regulation of Pnmt 1 0.40 0.1 0.49 100.00
49 INT86617 Negative_regulation of Positive_regulation of Prkg1 1 0.24 0 0.33 100.00
50 INT138107 Regulation of Gtpc 1 0.00 0.15 0.21 100.00
51 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 99.98
52 INT116164 Positive_regulation of Gene_expression of S1pr1 5 0.66 4.72 2.42 99.98
53 INT142694 Positive_regulation of PGAP1 3 0.08 2.78 8.68 99.98
54 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86 99.98
55 INT36365 Positive_regulation of SK 15 0.41 4.13 3.56 99.98
56 INT157076 Gene_expression of Acsf2 23 0.56 0.84 5.39 99.98
57 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1 99.98
58 INT228036 Negative_regulation of Cfl1 1 0.09 1.1 1.34 99.98
59 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49 99.98
60 INT102733 Gene_expression of Ubr5 1 0.31 0.31 0.91 99.98
61 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.98
62 INT142984 Positive_regulation of S1pr1 13 0.70 7.9 3.84 99.98
63 INT158461 Positive_regulation of Localization of Alas1 1 0.04 1.48 0.52 99.98
64 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 99.98
65 INT40216 Positive_regulation of Alas1 11 0.65 6.08 1.8 99.98
66 INT81828 Positive_regulation of Kcnk3 7 0.45 1.43 1.54 99.98
67 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 99.98
68 INT15158 Positive_regulation of Vegfc 6 0.68 1.07 6.52 99.98
69 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18 99.98
70 INT144395 Positive_regulation of Itfg1 1 0.15 0.56 0.33 99.98
71 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4 99.98
72 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28 99.98
73 INT66462 Positive_regulation of Negative_regulation of Phex 1 0.01 0.16 0.32 99.98
74 INT122578 Regulation of Gene_expression of SLC6A3 3 0.34 0.2 0.75 99.98
75 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09 99.98
76 INT165277 Negative_regulation of Acsf2 8 0.36 1.99 3.79 99.96
77 INT3483 Regulation of Fglu 3 0.01 0.52 1.11 99.94
78 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 99.92
79 INT38345 Positive_regulation of Nfyb 13 0.60 2.61 8.77 99.92
80 INT71569 Protein_catabolism of Map2 4 1.00 2.8 1.92 99.92
81 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.92
82 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 99.90
83 INT102732 Positive_regulation of Bicc1 1 0.07 0.5 0.48 99.90
84 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38 99.90
85 INT6807 Regulation of Gabrd 39 0.62 9.22 18.74 99.88
86 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.84
87 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 99.84
88 INT251 Regulation of INS 398 0.62 232.47 55.04 99.84
89 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.84
90 INT79709 Regulation of M1 13 0.24 4.8 4.9 99.84
91 INT148579 Regulation of rs 2 0.15 1.68 0.72 99.84
92 INT102735 Positive_regulation of Ubr5 1 0.24 0.16 0.45 99.84
93 INT58250 Negative_regulation of Imacq 1 0.06 0 0.97 99.84
94 INT58934 Negative_regulation of Srn1 3 0.16 0.19 0.84 99.84
95 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 99.84
96 INT95883 Regulation of IGES 2 0.11 0.7 1.18 99.84
97 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 99.82
98 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 99.82
99 INT158460 Localization of Alas1 1 0.06 0.74 0.26 99.82
100 INT17769 Positive_regulation of Dnase1 5 0.69 4.21 2.86 99.80
101 INT33419 Positive_regulation of Gene_expression of YY1 10 0.67 4.15 7.08 99.80
102 INT148578 Positive_regulation of Gene_expression of rs 1 0.29 0.45 1.01 99.80
103 INT148577 Positive_regulation of rs 2 0.29 0.44 1.01 99.80
104 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 99.80
105 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 99.80
106 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 99.78
107 INT19277 Gene_expression of Thra 4 0.58 0.68 1.1 99.78
108 INT228053 Positive_regulation of Binding of Sh3 1 0.15 0.57 0.82 99.78
109 INT228044 Positive_regulation of Sh3 1 0.15 0.57 0.82 99.78
110 INT228049 Positive_regulation of Sh3bgrl 1 0.27 0.65 0.58 99.78
111 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61 99.76
112 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.76
113 INT146661 Positive_regulation of D230030E09Rik 1 0.40 0.92 0.73 99.76
114 INT11580 Binding of Cebpz 8 0.40 7.16 2.19 99.72
115 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 99.72
116 INT114189 Positive_regulation of Cort 12 0.69 4.39 4.33 99.70
117 INT116163 Gene_expression of S1pr1 29 0.78 14.11 7.27 99.70
118 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.70
119 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.70
120 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.70
121 INT3484 Localization of Fglu 5 0.02 0.55 1.36 99.70
122 INT234 Binding of Alb 151 0.48 52.34 32.97 99.70
123 INT76056 Binding of Aspt1 1 0.01 0 0.38 99.70
124 INT45433 Positive_regulation of Localization of Acot1 18 0.45 1.9 4.32 99.70
125 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.68
126 INT812 Localization of INS 1026 0.81 515.6 145.31 99.68
127 INT3244 Negative_regulation of eCB 37 0.03 16.69 12.61 99.68
128 INT45437 Localization of Acot1 84 0.79 17.37 22.18 99.68
129 INT115227 Regulation of Localization of Acot1 12 0.60 0.15 3.51 99.68
130 INT49631 Gene_expression of Slc43a3 14 0.59 4.15 2.15 99.68
131 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 99.68
132 INT3214 Localization of Ins1 527 0.80 196.9 79.26 99.68
133 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59 99.68
134 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75 99.68
135 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87 99.68
136 INT69368 Positive_regulation of Binding of Tdo2 2 0.44 0 0.28 99.68
137 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.66
138 INT326485 Negative_regulation of Positive_regulation of PGAP1 1 0.01 0.08 0.49 99.66
139 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 99.66
140 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 99.66
141 INT116802 Regulation of Camk4 4 0.20 1.77 3.29 99.66
142 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67 99.64
143 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 99.62
144 INT51084 Binding of Insr 13 0.30 4.25 4.23 99.62
145 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 99.60
146 INT4651 Gene_expression of Cebpz 39 0.00 20.19 8.5 99.60
147 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73 99.60
148 INT81247 Gene_expression of Tnnt2 9 0.31 2.06 2.37 99.60
149 INT2407 Regulation of GAST 26 0.62 5.31 10.04 99.60
150 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.58
151 INT28782 Negative_regulation of Slc43a3 13 0.35 5.02 5.01 99.58
152 INT206995 Binding of Sh3 5 0.16 0.68 0.82 99.58
153 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 99.56
154 INT17770 Negative_regulation of Dnase1 1 0.46 0 0.81 99.56
155 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48 99.54
156 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 99.52
157 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 99.52
158 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84 99.52
159 INT7901 Positive_regulation of Ppidl1 14 0.15 1.58 8.8 99.52
160 INT322475 Negative_regulation of PGAP1 9 0.36 4.78 4.69 99.50
161 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48 99.48
162 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62 99.48
163 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08 99.48
164 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.48
165 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46 99.48
166 INT23606 Regulation of Atp2b4 10 0.25 3.33 1.63 99.46
167 INT217875 Gene_expression of AD5 41 0.40 19.85 2.28 99.46
168 INT1352 Localization of Acot1 728 0.80 73.01 296.01 99.44
169 INT228051 Negative_regulation of Camp 1 0.32 0.96 0.98 99.44
170 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 99.42
171 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 99.42
172 INT3978 Regulation of Regulation of cerebral blood flow 2 0.00 0.57 1.16 99.42
173 INT39503 Positive_regulation of KCNK3 3 0.47 0.09 1.29 99.42
174 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.40
175 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 99.40
176 INT123402 Positive_regulation of KCNK18 2 0.70 0 0.66 99.40
177 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14 99.40
178 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.38
179 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.38
180 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74 99.38
181 INT141750 Positive_regulation of Localization of Syt1 10 0.67 5.53 5.28 99.38
182 INT178799 Positive_regulation of Camp 8 0.43 4.37 2.1 99.38
183 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 99.38
184 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 99.38
185 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97 99.36
186 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.36
187 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68 99.36
188 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.36
189 INT228035 Binding of Sh3bgrl 1 0.24 0.58 0.83 99.36
190 INT104527 Binding of FSCN1 18 0.23 14.75 19.6 99.36
191 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 99.36
192 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 99.36
193 INT2140 Regulation of REN 104 0.62 28.24 24.49 99.36
194 INT38344 Regulation of Nfyb 1 0.18 0 0.41 99.34
195 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.32
196 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 99.32
197 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 99.30
198 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 99.30
199 INT78323 Negative_regulation of PSME1 1 0.37 0.5 0.78 99.28
200 INT22723 Negative_regulation of Hrtrt1 6 0.21 1.52 3.73 99.28
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