P:ketamine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 6126
Hot Single Events 200
Hot Interactions 34

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for ketamine. They are ordered first by their pain relevance and then by number of times they were reported for ketamine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT151961 Rbm39 Positive_regulation of Insrr 1 0.17 0.26 0.89 100.00
2 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37 100.00
3 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72 99.84
4 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66 99.68
5 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 99.66
6 INT167154 FPR1 Positive_regulation of ING1 1 0.18 0.18 0.44 99.58
7 INT293056 Binding of ANXA5 and GOPC 1 0.06 0.51 0.19 98.24
8 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66 98.20
9 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35 97.92
10 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66 97.84
11 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19 96.14
12 INT218062 Abat Negative_regulation of Ctse 1 0.03 0.25 0.89 96.00
13 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75 94.40
14 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92 92.96
15 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33 92.72
16 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68 92.60
17 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46 92.08
18 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43 91.60
19 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79 91.44
20 INT269064 Il6 Positive_regulation of Gene_expression of Cybb 1 0.75 0.79 0.31 88.20
21 INT269055 Il6 Positive_regulation of Gene_expression of Gopc 1 0.21 0.06 0.12 88.20
22 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39 88.16
23 INT15578 GNRH1 Regulation of Localization of Lhb 3 0.07 0 1.22 87.76
24 INT134324 Gh Regulation of Gene_expression of F8a 1 0.07 0 0.33 86.24
25 INT15577 Lhb Positive_regulation of GNRH1 1 0.14 0 0.88 85.44
26 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36 84.40
27 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81 83.60
28 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81 83.44
29 INT213815 Binding of Tfeb and Stub1 1 0.13 0.09 0.04 81.96
30 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61 81.48
31 INT59845 Negative_regulation of IFNA1 Positive_regulation of Gpi1 1 0.09 0 0.37 81.12
32 INT59844 IFNA1 Positive_regulation of Gpi1 1 0.10 0 0.37 80.44
33 INT59843 IFNA1 Positive_regulation of IFNA1 Positive_regulation of Gpi1 1 0.05 0 0.37 80.44
34 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42 80.08
35 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59 78.56
36 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49 77.64
37 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2 77.64
38 INT78558 Pomgnt1 Negative_regulation of Shisa9 1 0.00 0 0.35 77.28
39 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11 75.52
40 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27 72.48
41 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28 72.16
42 INT166145 Binding of Rrad and Rce1 1 0.04 0 0.14 71.04
43 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17 70.16
44 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12 69.44
45 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17 67.76
46 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17 67.76
47 INT308495 Pcsk5 Regulation of CFI 1 0.01 0.22 0.85 67.44
48 INT176549 Mtv7 Positive_regulation of Spp1 1 0.26 0.86 0.03 67.04
49 INT176540 Pik3cd Positive_regulation of Spp1 1 0.11 1.8 0.03 67.04
50 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 64.08
51 INT269060 Il6 Positive_regulation of Cybb 1 0.75 0.65 0.26 63.68
52 INT198536 Cox11 Negative_regulation of HK1 1 0.22 0.08 0.41 63.36
53 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15 62.24
54 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12 62.24
55 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12 61.28
56 INT10552 Penk Positive_regulation of Regulation of Cebpz 1 0.44 0.25 1.03 58.68
57 INT321917 1200011M11Rik Positive_regulation of DAO 1 0.01 0.9 0.27 56.44
58 INT198538 Binding of HK1 and Cox11 1 0.14 0 0.24 55.28
59 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2 55.28
60 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27 53.56
61 INT293055 Binding of ANXA5 and PRSS1 1 0.00 0.59 0 50.00
62 INT139032 Binding of Oprm1 and Tp63 1 0.25 0.05 0 50.00
63 INT139033 Positive_regulation of Binding of Oprm1 and Tp63 1 0.32 0.05 0 50.00
64 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 48.24
65 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41 45.92
66 INT269071 Binding of IL6 and Il6 1 0.40 0.73 0.19 45.20
67 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41 45.04
68 INT235693 Binding of Clcn1 and Gab2 1 0.19 2.96 0 44.68
69 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29 42.40
70 INT355220 Negative_regulation of Binding of Ocln and Tjp1 1 0.21 0.14 0 42.40
71 INT198523 Ranbp2 Negative_regulation of Cox11 1 0.42 0 0.17 41.92
72 INT198540 Ranbp2 Negative_regulation of HK1 1 0.19 0 0.17 41.48
73 INT194341 Binding of Trpv1 and Accn3 1 0.30 0.68 0.16 39.76
74 INT269069 Binding of Cyba and Cybb 1 0.18 0.18 0.09 32.32
75 INT269056 Positive_regulation of Binding of Cyba and Cybb 1 0.24 0.18 0.09 32.32
76 INT198530 Ranbp2 Negative_regulation of Ranbp2 Negative_regulation of HK1 1 0.22 0 0.05 30.32
77 INT170558 Binding of Myoc and Narf 1 0.04 3.03 0.63 29.36
78 INT198526 Ranbp2 Positive_regulation of Hk1 1 0.51 0 0 27.56
79 INT198529 Ranbp2 Positive_regulation of Cox11 1 0.68 0 0 27.56
80 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 25.28
81 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19 13.88
82 INT220388 Gh1 Regulation of Cish 1 0.03 0.29 0.28 13.84
83 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 12.12
84 INT187333 Binding of C4bpa and Car1 1 0.08 0 0.52 12.08
85 INT258636 Binding of Alb and Is(HSR;1)1Icg 1 0.05 0 0.44 11.12
86 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 10.40
87 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 10.08
88 INT340839 Binding of NOVA2 and Regulation of Cfp 1 0.02 0 0.32 9.92
89 INT269066 Binding of Hspa8 and Il6 1 0.00 0.74 0.23 9.52
90 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 8.96
91 INT201208 Positive_regulation of Binding of Crisp1 and Eddm3b 1 0.02 0 0 7.68
92 INT201209 Binding of Crisp1 and Eddm3b 1 0.02 0 0 7.68
93 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08 6.24
94 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 5.00
95 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 5.00
96 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
97 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
98 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
99 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 5.00
100 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
101 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
102 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51 5.00
103 INT231968 Binding of Cpn1 and Rvm 1 0.11 1.57 2.45 5.00
104 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44 5.00
105 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26 5.00
106 INT231967 Binding of Psmd1 and Cpn1 1 0.06 1.39 2.25 5.00
107 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25 5.00
108 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24 5.00
109 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
110 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 5.00
111 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 5.00
112 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
113 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
114 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76 5.00
115 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 5.00
116 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
117 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 5.00
118 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54 5.00
119 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
120 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
121 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42 5.00
122 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42 5.00
123 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42 5.00
124 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4 5.00
125 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
126 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 5.00
127 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31 5.00
128 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 5.00
129 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
130 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 5.00
131 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22 5.00
132 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 5.00
133 INT206766 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Nkx1-1 1 0.01 0.22 1.16 5.00
134 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
135 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15 5.00
136 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15 5.00
137 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14 5.00
138 INT289659 Tnfrsf1b Negative_regulation of Mcpt3 1 0.02 0.82 1.13 5.00
139 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 5.00
140 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12 5.00
141 INT161011 Binding of Cpe and St13 2 0.03 0.61 1.07 5.00
142 INT250777 Binding of Cxcl10 and Cxcr1 1 0.14 3.1 1.04 5.00
143 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 5.00
144 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01 5.00
145 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1 5.00
146 INT267886 Arl10 Positive_regulation of Insrr 1 0.00 0.07 0.98 5.00
147 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97 5.00
148 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
149 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94 5.00
150 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93 5.00
151 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92 5.00
152 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92 5.00
153 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
154 INT247759 Binding of Ccrl2 and Rarres2 1 0.26 1.19 0.9 5.00
155 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
156 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
157 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87 5.00
158 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87 5.00
159 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87 5.00
160 INT337899 Positive_regulation of MC3R Positive_regulation of Gene_expression of Bdnf 1 0.31 0 0.87 5.00
161 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85 5.00
162 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84 5.00
163 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 5.00
164 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
165 INT289658 Tnfrsf1a Positive_regulation of Mcpt1 1 0.02 0.76 0.81 5.00
166 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 5.00
167 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8 5.00
168 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
169 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 5.00
170 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
171 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
172 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
173 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76 5.00
174 INT343599 Gys1 Regulation of Tst 1 0.01 0 0.75 5.00
175 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74 5.00
176 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73 5.00
177 INT254030 Binding of Kcna6 and AIS 2 0.03 0 0.72 5.00
178 INT288323 Glyr1 Regulation of Sds 1 0.05 0.2 0.72 5.00
179 INT337157 Iqgap1 Regulation of Gene_expression of Ros1 1 0.07 1.91 0.72 5.00
180 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72 5.00
181 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.68 0.71 5.00
182 INT281857 Binding of Ltp and Cnnm1 1 0.00 0 0.71 5.00
183 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71 5.00
184 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00
185 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7 5.00
186 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69 5.00
187 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69 5.00
188 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69 5.00
189 INT282664 Binding of Aif1 and Gfap 1 0.06 0 0.69 5.00
190 INT288326 Sds Positive_regulation of Glyr1 1 0.10 0.12 0.68 5.00
191 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68 5.00
192 INT288324 Sds Positive_regulation of Gene_expression of Glyr1 1 0.10 0.12 0.68 5.00
193 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68 5.00
194 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66 5.00
195 INT267888 St13 Positive_regulation of Insrr 1 0.00 0.07 0.64 5.00
196 INT267891 Cpe Positive_regulation of Localization of Insrr 1 0.00 0 0.64 5.00
197 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 5.00
198 INT275562 Il1 Regulation of Gene_expression of Cxcl2 1 0.02 1.41 0.64 5.00
199 INT239488 Spna1 Negative_regulation of Gene_expression of Timp1 1 0.00 0.94 0.62 5.00
200 INT265707 Binding of NA and Cfp 1 0.01 0 0.62 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for ketamine. They are ordered first by their pain relevance and then by number of times they were reported in ketamine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT322474 Regulation of PGAP1 1 0.38 4.82 5.06 100.00
2 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
3 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 100.00
4 INT170444 Binding of Gopc 172 0.39 45.05 20.71 100.00
5 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 100.00
6 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 100.00
7 INT104527 Binding of FSCN1 18 0.23 14.75 19.6 100.00
8 INT36859 Positive_regulation of ACOT2 1 0.01 0.41 1.1 100.00
9 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 100.00
10 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82 100.00
11 INT104342 Regulation of FSCN1 4 0.15 3.18 4.84 100.00
12 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
13 INT847 Regulation of Lhb 131 0.61 22.08 46.54 100.00
14 INT1596 Negative_regulation of Oprl1 61 0.57 13.5 38.41 100.00
15 INT10088 Negative_regulation of Positive_regulation of TAOK3 1 0.57 0 1.33 100.00
16 INT10087 Positive_regulation of TAOK3 1 0.67 0 1.32 100.00
17 INT36858 Regulation of ACOT2 1 0.01 0.26 0.62 100.00
18 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93 100.00
19 INT73642 Positive_regulation of Ctse 12 0.44 5.57 6.79 100.00
20 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 100.00
21 INT8053 Regulation of Negative_regulation of MBD2 1 0.16 0 0.5 100.00
22 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 100.00
23 INT152 Negative_regulation of MBD2 31 0.38 3.95 11.31 100.00
24 INT245587 Regulation of Car1 13 0.27 4.68 5.72 100.00
25 INT54805 Regulation of Ahr 7 0.22 4.14 1.41 100.00
26 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 100.00
27 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
28 INT48 Positive_regulation of Localization of Ren 69 0.70 12.47 18.03 100.00
29 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 100.00
30 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 100.00
31 INT332775 Regulation of Phosphorylation of FSCN1 1 0.02 0.19 0.95 100.00
32 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
33 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08 100.00
34 INT134773 Regulation of SLC6A12 1 0.32 0.35 0.69 100.00
35 INT4629 Regulation of Fshb 12 0.49 1.93 5.95 100.00
36 INT9946 Regulation of Localization of LHB 27 0.52 2.47 11.08 100.00
37 INT2695 Regulation of DBH 5 0.45 1.09 2.48 100.00
38 INT7035 Regulation of CGA 87 0.45 29.04 28.45 100.00
39 INT2330 Regulation of CB 78 0.10 20.46 32.6 100.00
40 INT155215 Regulation of ACTN1 1 0.30 0.17 0.37 100.00
41 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 100.00
42 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
43 INT293061 Regulation of Binding of ANXA5 1 0.12 0.58 0.25 100.00
44 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67 100.00
45 INT208371 Localization of Ahr 2 0.50 1.9 0.66 100.00
46 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
47 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48 100.00
48 INT65538 Regulation of Positive_regulation of Nfkb1 17 0.51 8.31 6.5 100.00
49 INT2140 Regulation of REN 104 0.62 28.24 24.49 100.00
50 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 100.00
51 INT3958 Regulation of CNDP1 5 0.35 0.86 0.78 100.00
52 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 100.00
53 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89 100.00
54 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 100.00
55 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
56 INT165000 Positive_regulation of Negative_regulation of GRIN1 1 0.49 1.18 1.36 100.00
57 INT29290 Regulation of Gene_expression of PRL 13 0.49 6.46 5.23 100.00
58 INT1648 Regulation of LHB 21 0.61 3.32 9.6 100.00
59 INT113532 Binding of AP2M1 1 0.47 0.19 0.47 100.00
60 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 100.00
61 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 100.00
62 INT37915 Regulation of Positive_regulation of Mb 3 0.44 0.59 0.7 100.00
63 INT106083 Negative_regulation of Kcna1 4 0.21 0.92 1.92 100.00
64 INT166332 Positive_regulation of Negative_regulation of Kcna1 1 0.22 0 1.2 100.00
65 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 100.00
66 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31 100.00
67 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7 100.00
68 INT94925 Regulation of Gene_expression of Grip2 7 0.55 4.23 3.18 100.00
69 INT54057 Localization of 20T 5 0.08 1.12 2.64 100.00
70 INT20117 Regulation of Imacq 2 0.14 0 1 100.00
71 INT108351 Negative_regulation of Localization of 20T 1 0.01 0.1 0.38 100.00
72 INT45888 Regulation of Localization of Kitl 1 0.45 0 0.18 100.00
73 INT23035 Regulation of Il1a 6 0.60 5.69 4.25 100.00
74 INT78956 Regulation of Transcription of Ptgs1 3 0.35 1.42 1.7 100.00
75 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26 99.98
76 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.98
77 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84 99.98
78 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.98
79 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.98
80 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31 99.98
81 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.98
82 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.98
83 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 99.98
84 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.98
85 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 99.98
86 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 99.98
87 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85 99.98
88 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82 99.98
89 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 99.98
90 INT58861 Positive_regulation of Localization of Ldha 2 0.25 0.1 1.26 99.98
91 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 99.98
92 INT91374 Negative_regulation of Gene_expression of Nfkb1 12 0.58 5.06 1.75 99.98
93 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 99.98
94 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 99.98
95 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 99.96
96 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 99.96
97 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41 99.96
98 INT1045 Localization of LH 1211 0.81 87.04 456.25 99.92
99 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.92
100 INT109724 Phosphorylation of FSCN1 5 0.07 3.15 8.82 99.92
101 INT332774 Positive_regulation of Phosphorylation of FSCN1 1 0.02 0.69 2.63 99.92
102 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 99.92
103 INT2649 Regulation of Calca 433 0.62 146.05 330.95 99.92
104 INT48883 Negative_regulation of GRIN3B 19 0.54 14.53 11.5 99.90
105 INT5561 Negative_regulation of GRIN2D 10 0.50 2.46 4.88 99.90
106 INT41490 Regulation of Acot1 14 0.45 1.59 3.34 99.90
107 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.88
108 INT15993 Regulation of FPR1 8 0.40 1.24 2.42 99.88
109 INT115232 Negative_regulation of Ctse 2 0.36 1.29 3.37 99.88
110 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99 99.88
111 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 99.88
112 INT322475 Negative_regulation of PGAP1 9 0.36 4.78 4.69 99.86
113 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41 99.86
114 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37 99.86
115 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 99.84
116 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 99.84
117 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 99.84
118 INT96092 Binding of ANXA5 24 0.36 14.51 2.6 99.84
119 INT189177 Positive_regulation of Gene_expression of FSCN1 12 0.11 3.77 6.12 99.84
120 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08 99.84
121 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 99.84
122 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79 99.84
123 INT46797 Negative_regulation of Cyp3a62 27 0.59 7.06 13.97 99.84
124 INT14881 Gene_expression of Car3 49 0.73 14.89 9.94 99.84
125 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 99.84
126 INT12183 Negative_regulation of Cyp2d1 11 0.58 3.11 5.49 99.84
127 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 99.84
128 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32 99.84
129 INT33884 Gene_expression of Ptprg 3 0.59 0.83 1.07 99.84
130 INT261363 Negative_regulation of Gene_expression of Ptprg 1 0.01 0.84 0.31 99.84
131 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.82
132 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 99.82
133 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 99.82
134 INT167164 Negative_regulation of Phosphorylation of ING1 1 0.33 0.2 0.77 99.82
135 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15 99.82
136 INT17584 Regulation of tf 12 0.50 4.69 10.39 99.82
137 INT322476 Positive_regulation of Negative_regulation of PGAP1 1 0.29 0.46 0.28 99.82
138 INT1352 Localization of Acot1 728 0.80 73.01 296.01 99.80
139 INT11177 Localization of Ldha 17 0.81 5.74 6.13 99.80
140 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17 99.80
141 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 99.80
142 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.80
143 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 99.80
144 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 99.80
145 INT162835 Positive_regulation of Cybb 38 0.68 16.09 3.02 99.80
146 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 99.80
147 INT13501 Binding of Drd2 65 0.48 23.76 35.6 99.78
148 INT170548 Regulation of Narf 1 0.06 34.17 2.18 99.78
149 INT50311 Binding of Htas2 9 0.47 1.19 4.91 99.78
150 INT155214 Negative_regulation of ACTN1 1 0.28 0.16 0.51 99.78
151 INT18621 Binding of ABAT 28 0.36 9.88 18.04 99.76
152 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 99.76
153 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.76
154 INT1438 Localization of Pomc 360 0.81 101.26 116.47 99.76
155 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 99.76
156 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 99.76
157 INT3301 Positive_regulation of Slc43a3 26 0.55 5.48 10.81 99.76
158 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 99.76
159 INT119806 Negative_regulation of Cir1 2 0.23 0.18 0.5 99.76
160 INT17271 Positive_regulation of CDNF 11 0.28 2.69 5.03 99.76
161 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 99.74
162 INT138488 Negative_regulation of Il13 3 0.23 1.1 1.29 99.74
163 INT27316 Negative_regulation of TPO 7 0.38 7.26 4.42 99.74
164 INT132663 Negative_regulation of GRINA 1 0.27 0.55 0.53 99.74
165 INT27315 Positive_regulation of TPO 17 0.45 9.84 2.28 99.74
166 INT3276 Binding of LH 16 0.37 4.76 5.94 99.74
167 INT25590 Positive_regulation of Positive_regulation of Fuca2 1 0.22 0.15 0.76 99.74
168 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 99.72
169 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 99.72
170 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.70
171 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27 99.70
172 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 99.70
173 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53 99.70
174 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 99.70
175 INT49633 Positive_regulation of NBL1 9 0.37 0.38 4.13 99.70
176 INT23226 Positive_regulation of tf 23 0.43 15.55 14.37 99.70
177 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26 99.70
178 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 99.70
179 INT175535 Gene_expression of GPC3 5 0.29 4.17 1.74 99.70
180 INT15010 Negative_regulation of Positive_regulation of Gpi1 2 0.27 0 1.27 99.70
181 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.68
182 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.68
183 INT49089 Gene_expression of Rab38 22 0.45 6.79 13.76 99.68
184 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.68
185 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 99.68
186 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 99.68
187 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.66
188 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.66
189 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 99.66
190 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 99.66
191 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.64
192 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 99.64
193 INT100009 Phosphorylation of FPR1 3 0.38 1.02 1.9 99.62
194 INT16624 Localization of Grin1 38 0.79 8.46 17.15 99.62
195 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 99.62
196 INT84673 Localization of Nos1 19 0.80 5.01 5.62 99.62
197 INT2212 Binding of Abat 89 0.48 18.36 63.99 99.62
198 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 99.62
199 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 99.62
200 INT50559 Binding of A1cf 4 0.34 0.8 2.97 99.62
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