P:local anesthetic

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Drug class
Synonyms Local Anesthetics
Pain Specific Yes
Documents 10589
Hot Single Events 200
Hot Interactions 46

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for local anesthetic. They are ordered first by their pain relevance and then by number of times they were reported for local anesthetic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT82767 Binding of HP and MLRG 1 0.00 0 0.71 100.00
2 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73 100.00
3 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72 100.00
4 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72 100.00
5 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45 100.00
6 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09 99.98
7 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1 99.84
8 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08 99.84
9 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09 99.78
10 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 99.78
11 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44 99.76
12 INT158473 Binding of El1 and El2 1 0.20 0.42 0.86 99.52
13 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13 98.64
14 INT111244 Binding of BRS3 and SCN5A 1 0.00 0.72 0.48 98.28
15 INT1211 Binding of Kitl and Cpz 1 0.27 0 0.58 98.20
16 INT1210 Negative_regulation of Binding of Kitl and Cpz 1 0.33 0 0.58 98.20
17 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7 98.10
18 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7 98.10
19 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71 97.86
20 INT47607 Psl1 Positive_regulation of Odc1 1 0.51 0.14 0.19 97.68
21 INT47610 Regulation of Psl1 Positive_regulation of Odc1 1 0.26 0.06 0.1 97.68
22 INT48382 CSF2 Positive_regulation of Gene_expression of ITGAM 1 0.23 0.25 0.49 97.60
23 INT59945 Binding of C2 and Srms 1 0.00 0 0.53 96.80
24 INT159720 Slc5a7 Regulation of Gene_expression of Acot1 1 0.12 0 0.19 96.72
25 INT159722 Slc5a7 Positive_regulation of Gene_expression of Acot1 1 0.12 0 0.19 96.72
26 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31 96.60
27 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92 95.44
28 INT47609 Positive_regulation of Psl1 Positive_regulation of Odc1 1 0.45 0 0.1 95.12
29 INT13192 FPR1 Positive_regulation of Localization of LRBA 1 0.47 0 0.53 95.08
30 INT13191 FPR1 Positive_regulation of Localization of GUSB 1 0.31 0 0.53 95.08
31 INT48379 CSF2 Negative_regulation of Gene_expression of SELL 1 0.22 0.2 0.48 94.40
32 INT68061 Binding of NA and Regulation of INA 1 0.09 0.08 0.46 92.16
33 INT156091 Afm Regulation of Epc1 1 0.01 0 0.09 89.00
34 INT48381 CSF2 Positive_regulation of ITGAM 2 0.30 0.38 0.95 88.36
35 INT48387 CSF2 Positive_regulation of SELL 1 0.18 0.24 0.71 88.36
36 INT48386 CSF2 Positive_regulation of Positive_regulation of ITGAM 1 0.16 0.24 0.7 88.36
37 INT48377 CSF2 Positive_regulation of CSF2 Positive_regulation of ITGAM 1 0.06 0.24 0.7 88.36
38 INT48383 CSF2 Regulation of Gene_expression of ITGB2 1 0.11 0.2 0.44 86.64
39 INT48389 CSF3 Regulation of Gene_expression of ITGB2 1 0.25 0.2 0.44 86.64
40 INT48385 CSF2 Regulation of Gene_expression of ITGAM 2 0.16 0.29 0.68 86.24
41 INT48388 CSF3 Regulation of Gene_expression of ITGAM 1 0.35 0.2 0.44 86.24
42 INT48384 CSF2 Regulation of Gene_expression of SELL 1 0.17 0.4 0.83 85.36
43 INT48380 CSF3 Regulation of Gene_expression of SELL 1 0.41 0.4 0.83 85.36
44 INT65909 LAMB1 Positive_regulation of GANAB 1 0.00 0 0.45 82.04
45 INT1233 Gcg Positive_regulation of Pdpk1 1 0.27 0 0.14 80.88
46 INT35963 Binding of ALB and MPG 1 0.40 0 0.3 80.28
47 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64 79.28
48 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55 78.96
49 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 78.32
50 INT193274 Phax Regulation of Brs3 1 0.00 0 0.8 78.32
51 INT159721 Hc3 Negative_regulation of Gene_expression of Acot1 1 0.04 0 0.19 77.52
52 INT113992 Binding of HRH1 and LIAS 1 0.00 0.09 0.38 77.24
53 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88 75.20
54 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86 75.20
55 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15 75.00
56 INT76662 MIR548K Negative_regulation of ZCWPW1 1 0.00 0 0.24 75.00
57 INT44759 Negative_regulation of PLAT Positive_regulation of ODC1 1 0.27 0 0.27 75.00
58 INT44760 PLAT Positive_regulation of ODC1 1 0.29 0 0.27 75.00
59 INT60794 Binding of TREH and Chrna9 1 0.00 0 1.04 73.44
60 INT60793 Negative_regulation of Binding of TREH and Chrna9 1 0.00 0 0.53 73.44
61 INT60788 Binding of TREH and BHLHE23 1 0.00 0 0.52 72.96
62 INT60051 Ptger1 Positive_regulation of STAB2 1 0.00 0.77 0.68 70.08
63 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06 64.40
64 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3 64.32
65 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27 63.36
66 INT167194 FPR1 Positive_regulation of Gene_expression of ITGAM 1 0.52 0.8 0.53 62.32
67 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 60.80
68 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24 59.84
69 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86 59.84
70 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06 58.96
71 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13 58.60
72 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88 54.56
73 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88 54.00
74 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16 53.60
75 INT34903 CALM1 Negative_regulation of Gene_expression of IL2 1 0.18 0 0.2 50.44
76 INT84499 Chrm3 Positive_regulation of Ephb1 1 0.40 0 0 50.00
77 INT97091 HSPG2 Regulation of PRKCA 1 0.04 0 0 50.00
78 INT165438 PTAFR Positive_regulation of Gene_expression of ITGAM 1 0.45 0 0 50.00
79 INT53286 Binding of CYP1A2 and OPN1LW 1 0.03 0 0 50.00
80 INT84498 Negative_regulation of Chrm3 Positive_regulation of Ephb1 1 0.34 0 0 50.00
81 INT169096 Hpcl1 Regulation of Gene_expression of Slc12a5 1 0.02 0.05 0.95 47.80
82 INT47608 Negative_regulation of Psl1 Positive_regulation of Odc1 1 0.47 0.08 0 40.96
83 INT193276 Brs3 Negative_regulation of Gene_expression of Trpv1 1 0.03 0.14 0.75 17.12
84 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 16.80
85 INT305407 Binding of ST8SIA2 and ANTXR1 1 0.00 0.09 0.38 13.32
86 INT305405 Binding of KCNMA1 and ANTXR1 1 0.00 0.09 0.38 13.16
87 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78 6.40
88 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68 6.40
89 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
90 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
91 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 5.00
92 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
93 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 5.00
94 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
95 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
96 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
97 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
98 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
99 INT240658 Ngf Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.33 1.67 1.99 5.00
100 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
101 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
102 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
103 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
104 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
105 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
106 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
107 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
108 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
109 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45 5.00
110 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
111 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
112 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
113 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31 5.00
114 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23 5.00
115 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23 5.00
116 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23 5.00
117 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14 5.00
118 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09 5.00
119 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
120 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99 5.00
121 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91 5.00
122 INT193277 Binding of Cfd and Brs3 1 0.01 0.13 0.91 5.00
123 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87 5.00
124 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 5.00
125 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 5.00
126 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 5.00
127 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86 5.00
128 INT193278 Brs3 Positive_regulation of Gene_expression of Trpv1 1 0.04 0.09 0.86 5.00
129 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85 5.00
130 INT193287 Phax Regulation of STH 1 0.00 0.16 0.81 5.00
131 INT193279 Phax Regulation of Fth1 1 0.01 0.16 0.81 5.00
132 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81 5.00
133 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79 5.00
134 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
135 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
136 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77 5.00
137 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
138 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73 5.00
139 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
140 INT343365 Acsf2 Negative_regulation of Gabrd 1 0.04 0 0.61 5.00
141 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6 5.00
142 INT193265 CAP1 Regulation of STH 1 0.00 0 0.6 5.00
143 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59 5.00
144 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
145 INT297689 Atn1 Regulation of Gene_expression of Il6 1 0.02 1.13 0.44 5.00
146 INT297694 Positive_regulation of Binding of Il10 and Il13ra1 1 0.01 1.12 0.44 5.00
147 INT297696 Binding of Il10 and Il13ra1 1 0.00 1.12 0.43 5.00
148 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4 5.00
149 INT181080 Binding of Cx3cr1 and Darc 1 0.00 1.09 0.39 5.00
150 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39 5.00
151 INT241614 CCNA2 Regulation of PRB3 1 0.06 0 0.37 5.00
152 INT245343 Prkd1 Regulation of Slc3a1 1 0.29 0.47 0.36 5.00
153 INT170773 Binding of P2RX3 and P2RX2 1 0.07 0.27 0.35 5.00
154 INT309192 Binding of Car2 and Rbms1 1 0.05 0 0.34 5.00
155 INT343366 Acsf2 Negative_regulation of Acot1 1 0.05 0 0.31 5.00
156 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
157 INT309298 Binding of NA and ST8SIA2 1 0.00 0 0.28 5.00
158 INT334379 Ros1 Regulation of Cat 1 0.04 0.08 0.21 5.00
159 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
160 INT257844 STS Positive_regulation of Negative_regulation of CST7 1 0.01 0.24 0.19 5.00
161 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19 5.00
162 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
163 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18 5.00
164 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
165 INT328484 Ptgs1 Positive_regulation of Ros1 1 0.00 0.58 0.16 5.00
166 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15 5.00
167 INT344135 Negative_regulation of Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
168 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
169 INT344134 Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
170 INT297695 Binding of Atn1 and Fut1 1 0.01 0.68 0.12 5.00
171 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11 5.00
172 INT181076 Map4k4 Positive_regulation of Mapk8 1 0.11 0.47 0.11 5.00
173 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
174 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
175 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
176 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08 5.00
177 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07 5.00
178 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07 5.00
179 INT304349 Binding of HBN1 and MIR133B 1 0.00 0.29 0.07 5.00
180 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07 5.00
181 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
182 INT273372 IL6 Regulation of Regulation of TWIST1 1 0.10 0.1 0.07 5.00
183 INT273366 IL6 Regulation of TWIST1 1 0.06 0.1 0.07 5.00
184 INT304346 MIR133B Regulation of Gene_expression of MIR206 1 0.05 0.78 0.07 5.00
185 INT273363 SOCS3 Regulation of Protein_catabolism of SOCS1 1 0.02 0 0.07 5.00
186 INT273364 SOCS3 Regulation of SOCS1 1 0.02 0 0.07 5.00
187 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06 5.00
188 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06 5.00
189 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
190 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
191 INT261110 Cir1 Positive_regulation of Car2 1 0.04 0 0.04 5.00
192 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
193 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03 5.00
194 INT181086 Binding of Akt1 and Cdc42ep3 1 0.00 0.79 0.03 5.00
195 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03 5.00
196 INT181079 Binding of Akt1 and Errfi1 1 0.00 0.8 0.03 5.00
197 INT279698 Hc Regulation of Trpv1 1 0.01 0 0 5.00
198 INT253085 NPPA Positive_regulation of INS 1 0.32 0 0 5.00
199 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0 5.00
200 INT350486 Cebpb Positive_regulation of IgG2a 1 0.00 0.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for local anesthetic. They are ordered first by their pain relevance and then by number of times they were reported in local anesthetic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT117543 Regulation of Gene_expression of CD14 21 0.59 6.66 7.67 100.00
2 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
3 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 100.00
4 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
5 INT4616 Regulation of Maoa 40 0.62 6.09 15.94 100.00
6 INT59555 Binding of RYR1 39 0.42 8.65 4.92 100.00
7 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
8 INT117544 Regulation of CD14 24 0.45 5.85 6.66 100.00
9 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 100.00
10 INT117545 Regulation of Gene_expression of HLA-A 2 0.33 2.3 1.99 100.00
11 INT90038 Negative_regulation of Ifnar2 4 0.35 1.69 2.58 100.00
12 INT13209 Regulation of Binding of Trh 19 0.62 2.84 16.26 100.00
13 INT51137 Negative_regulation of GSTM1 39 0.43 14.74 6.5 100.00
14 INT56364 Regulation of Gene_expression of ITGAM 19 0.61 9.82 5.09 100.00
15 INT52907 Regulation of Gene_expression of HLA-DRA 28 0.34 5.94 5.96 100.00
16 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
17 INT15133 Regulation of HLA-DRA 19 0.34 5.84 3.9 100.00
18 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 100.00
19 INT179261 Gene_expression of SERPINA6 12 0.14 3.53 3.82 100.00
20 INT143551 Binding of KCNA1 13 0.46 8.81 2.81 100.00
21 INT9895 Binding of GHR 18 0.36 4.8 5.65 100.00
22 INT83109 Binding of LIAS 4 0.28 0 0.93 100.00
23 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 100.00
24 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02 100.00
25 INT165404 Regulation of Negative_regulation of Aldoa 1 0.11 0 0.65 100.00
26 INT18121 Binding of Maoa 20 0.48 2.4 9.3 100.00
27 INT179262 Localization of SERPINA6 4 0.16 1.29 1.1 100.00
28 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 100.00
29 INT1842 Binding of Hrasls 3 0.46 0.81 0.95 100.00
30 INT3935 Regulation of Localization of Rbp4 1 0.53 0 0.51 100.00
31 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8 100.00
32 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 100.00
33 INT1849 Binding of SUPT7L 14 0.47 0.95 5.44 100.00
34 INT37863 Regulation of HBG2 11 0.61 3.95 4.34 100.00
35 INT64164 Regulation of Prkca 34 0.62 10.44 30.99 100.00
36 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 100.00
37 INT100994 Positive_regulation of KCNK5 1 0.50 0 0.46 100.00
38 INT54357 Binding of PGE 4 0.23 1.46 2.22 100.00
39 INT46729 Regulation of Positive_regulation of Odc1 2 0.45 0.06 0.27 100.00
40 INT123419 Binding of NAV1 37 0.48 7.09 26.43 100.00
41 INT40453 Regulation of ODC1 7 0.45 1.08 1.58 100.00
42 INT73017 Regulation of Gene_expression of TAC1 5 0.54 0.44 3.08 100.00
43 INT34460 Binding of MBTPS1 6 0.24 0.95 1.37 100.00
44 INT101000 Positive_regulation of Positive_regulation of KCNK5 1 0.50 0 0.33 100.00
45 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55 100.00
46 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89 100.00
47 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62 100.00
48 INT11275 Regulation of Fos 37 0.60 5.79 18.18 100.00
49 INT44762 Regulation of Positive_regulation of ODC1 1 0.45 0 0.54 100.00
50 INT30570 Regulation of Scd2 1 0.04 0 0.35 100.00
51 INT73286 Regulation of Top1 1 0.05 0 0.17 100.00
52 INT65911 Binding of P4ha2 1 0.00 0 0.41 100.00
53 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 100.00
54 INT8778 Regulation of Ache 17 0.62 3.7 3.57 100.00
55 INT36883 Binding of Nmb 3 0.31 0 0.46 100.00
56 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.98
57 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55 99.98
58 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 99.98
59 INT100998 Negative_regulation of KCNK5 2 0.58 0 2.72 99.98
60 INT130648 Negative_regulation of Positive_regulation of Cyba 1 0.05 0.05 2 99.98
61 INT6791 Binding of NA 55 0.46 5.36 17.59 99.98
62 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49 99.98
63 INT3877 Negative_regulation of MUC7 30 0.57 1.62 12.89 99.98
64 INT108555 Positive_regulation of HK2 5 0.29 4.91 2.62 99.98
65 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 99.98
66 INT70722 Negative_regulation of Binding of SRRT 1 0.12 0 0.8 99.98
67 INT86602 Binding of KCNH2 14 0.36 4.65 2.58 99.98
68 INT55634 Negative_regulation of Gene_expression of FLII 7 0.41 1.77 5.11 99.98
69 INT11490 Binding of KCNMA1 13 0.37 3.61 3.32 99.98
70 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.98
71 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 99.98
72 INT110539 Negative_regulation of KCNK18 6 0.51 0.75 2.8 99.98
73 INT121085 Negative_regulation of GPHA2 3 0.22 1.99 1.56 99.98
74 INT2758 Binding of Dbp 36 0.44 8.3 14.47 99.98
75 INT59674 Gene_expression of Chrna6 8 0.47 2.12 3.94 99.98
76 INT73287 Positive_regulation of Top1 1 0.08 0 0.19 99.98
77 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.98
78 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 99.98
79 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07 99.98
80 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 99.96
81 INT19639 Negative_regulation of Gene_expression of Tbxa2r 17 0.55 7.69 5.01 99.96
82 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 99.96
83 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.92
84 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.92
85 INT3938 Localization of Rbp4 5 0.79 0.39 2.15 99.92
86 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 99.92
87 INT6578 Regulation of Pla2g1b 11 0.49 3.94 3.19 99.92
88 INT8462 Binding of MUC7 11 0.36 1.79 2.11 99.90
89 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 99.90
90 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41 99.90
91 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.90
92 INT135908 Regulation of Negative_regulation of Ephb1 1 0.24 0.4 1.49 99.90
93 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14 99.90
94 INT108553 Negative_regulation of Gene_expression of MAPKAPK5 1 0.09 1.23 1.1 99.88
95 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19 99.88
96 INT108556 Negative_regulation of BCL2L10 8 0.32 7.77 1.49 99.88
97 INT108557 Negative_regulation of Gene_expression of BCL2L10 2 0.32 1.21 1.07 99.88
98 INT145539 Negative_regulation of KCNK3 3 0.59 0 2.07 99.88
99 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42 99.88
100 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 99.84
101 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74 99.84
102 INT1376 Binding of Trh 121 0.48 20 69.86 99.84
103 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 99.84
104 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 99.84
105 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.84
106 INT110608 Negative_regulation of KCNK2 10 0.59 0.91 3.26 99.84
107 INT165408 Negative_regulation of Aldoa 1 0.11 0 1.33 99.84
108 INT108551 Gene_expression of MAPKAPK5 1 0.15 1.23 1.1 99.84
109 INT9355 Binding of pcp 81 0.46 10.41 24.22 99.84
110 INT108552 Regulation of MAPKAPK5 1 0.10 1.19 1.08 99.84
111 INT28583 Positive_regulation of Gene_expression of Atp7b 4 0.06 0.34 3.24 99.84
112 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11 99.84
113 INT100999 Negative_regulation of Positive_regulation of KCNK5 1 0.43 0 0.33 99.84
114 INT73112 Negative_regulation of Kcnk3 7 0.58 1.2 1.55 99.84
115 INT28582 Positive_regulation of Positive_regulation of Atp7b 1 0.04 0.1 1 99.84
116 INT58060 Negative_regulation of HMI 30 0.44 11.9 5.06 99.84
117 INT109442 Negative_regulation of Kcnk2 2 0.53 0.18 0.95 99.84
118 INT7883 Binding of ADRB2 18 0.47 5.49 7.37 99.82
119 INT70723 Binding of SRRT 1 0.10 0 1.38 99.82
120 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6 99.82
121 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 99.82
122 INT42943 Positive_regulation of Atrn 9 0.18 2.68 3.43 99.82
123 INT83110 Binding of LYNX1 1 0.02 0 0.45 99.82
124 INT59673 Negative_regulation of Chrna6 8 0.30 2.31 2.16 99.82
125 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 99.80
126 INT130649 Positive_regulation of Cyba 4 0.36 0.38 2.08 99.80
127 INT19620 Binding of CD86 30 0.47 12.01 9.89 99.80
128 INT14503 Binding of BCHE 13 0.48 3.95 1.85 99.80
129 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 99.80
130 INT5998 Negative_regulation of Glyr1 4 0.32 0.47 2.2 99.80
131 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 99.78
132 INT48391 Negative_regulation of Positive_regulation of ITGAM 5 0.43 3.13 2.46 99.78
133 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72 99.78
134 INT403 Localization of Trh 241 0.81 28.55 81.45 99.78
135 INT15993 Regulation of FPR1 8 0.40 1.24 2.42 99.78
136 INT107207 Binding of FHL1 3 0.40 0.76 0.5 99.78
137 INT48394 Negative_regulation of Negative_regulation of SELL 1 0.40 0.49 1.38 99.78
138 INT14282 Regulation of INA 5 0.23 0.87 2.42 99.78
139 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.76
140 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79 99.76
141 INT37041 Positive_regulation of ODC1 8 0.70 4.04 1.9 99.76
142 INT45092 Positive_regulation of Localization of Ctsb 1 0.50 0 0.19 99.76
143 INT92397 Binding of Epc1 6 0.30 1.93 0.53 99.76
144 INT17103 Negative_regulation of Prep 15 0.38 4.95 4.71 99.76
145 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 99.74
146 INT4204 Positive_regulation of St8sia2 1 0.69 0.19 0.79 99.74
147 INT75497 Regulation of JUN 28 0.61 11.04 7.09 99.74
148 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 99.72
149 INT1843 Positive_regulation of Hrasls 16 0.69 2.16 5.08 99.72
150 INT1841 Negative_regulation of Hrasls 15 0.48 6.85 4.56 99.72
151 INT67274 Negative_regulation of Tes 2 0.38 0.09 0.82 99.72
152 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 99.70
153 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36 99.70
154 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 99.70
155 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 99.70
156 INT59559 Negative_regulation of Binding of Olr639 1 0.01 0 0.94 99.68
157 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35 99.66
158 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63 99.66
159 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 99.66
160 INT19646 Binding of KLRD1 9 0.04 4.27 2.35 99.64
161 INT129565 Negative_regulation of Cuzd1 5 0.43 0.65 1.24 99.64
162 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 99.64
163 INT110605 Gene_expression of KCNK2 24 0.78 5.71 6.85 99.64
164 INT10706 Regulation of Il6 150 0.62 93.23 62.34 99.64
165 INT35269 Localization of SGCG 38 0.78 14.68 9.01 99.64
166 INT168523 Localization of Cdh23 2 0.22 0.27 0.15 99.64
167 INT168525 Localization of GPR98 1 0.21 0.17 0.1 99.64
168 INT168524 Localization of Ush1g 1 0.22 0.17 0.1 99.64
169 INT168521 Localization of Myo7a 1 0.18 0.17 0.1 99.64
170 INT168526 Localization of USH2A 1 0.20 0.17 0.1 99.64
171 INT168522 Localization of Ush1c 1 0.21 0.17 0.1 99.64
172 INT82768 Binding of MLRG 5 0.23 0.54 2.22 99.60
173 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.60
174 INT108554 Gene_expression of BCL2L10 6 0.58 3.18 1.25 99.60
175 INT134460 Positive_regulation of CISD1 5 0.04 1.23 4.8 99.56
176 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.56
177 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24 99.56
178 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.56
179 INT132063 Negative_regulation of Negative_regulation of SCN11A 1 0.15 0 0.73 99.56
180 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 99.56
181 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32 99.56
182 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 99.54
183 INT2978 Gene_expression of Tbxa2r 76 0.77 28.4 21.27 99.54
184 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.54
185 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 99.54
186 INT309305 Regulation of Negative_regulation of NAV1 1 0.26 0 0.77 99.54
187 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.52
188 INT128 Negative_regulation of Localization of OXTR 7 0.59 2.92 2.86 99.52
189 INT129 Localization of OXTR 51 0.80 11.08 15.36 99.52
190 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2 99.52
191 INT14114 Binding of Adra2a 30 0.48 4.24 18.53 99.52
192 INT29009 Positive_regulation of Fgl2 4 0.41 0.96 0.36 99.52
193 INT165407 Regulation of Aldoa 1 0.11 0 0.53 99.50
194 INT11996 Gene_expression of Ina 34 0.67 4.8 13.82 99.50
195 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.48
196 INT46733 Positive_regulation of Odc1 16 0.70 2.1 1.71 99.48
197 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.48
198 INT27627 Binding of Rac1 41 0.41 22.88 13.68 99.48
199 INT23825 Negative_regulation of Binding of Trh 17 0.59 1.62 11.24 99.44
200 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64 99.44
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox