P:low threshold mechanoreceptor

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pChart

Pain Term
Category Anatomy
Synonyms Low Threshold Mechanoreceptors
Pain Specific Yes
Documents 43
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for low threshold mechanoreceptor. They are ordered first by their pain relevance and then by number of times they were reported for low threshold mechanoreceptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8 67.28
2 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12 58.36
3 INT208623 Nmbr Positive_regulation of Prph 1 0.04 0.15 0.36 58.36
4 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 43.04
5 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11 42.64
6 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 5.00
7 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
8 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
9 INT228679 Binding of Rps6kb1 and Fig4 1 0.08 0.08 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for low threshold mechanoreceptor. They are ordered first by their pain relevance and then by number of times they were reported in low threshold mechanoreceptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
2 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 97.52
3 INT93195 Negative_regulation of Accn2 14 0.59 7.23 6.31 96.36
4 INT5587 Regulation of Fos 191 0.62 40.81 99.7 92.08
5 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 90.72
6 INT11331 Positive_regulation of FANCB 5 0.49 2.23 1.09 85.44
7 INT104538 Positive_regulation of DLK1 3 0.40 2.79 0.17 85.44
8 INT107846 Transcription of P2ry2 6 0.46 2.06 2.52 83.16
9 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 81.12
10 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 79.76
11 INT208617 Binding of Nmbr 1 0.25 1.57 2.84 79.52
12 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 79.20
13 INT208607 Gene_expression of Nmbr 1 0.41 0.44 0.89 78.48
14 INT208613 Localization of Nmbr 1 0.40 0.2 0.46 75.60
15 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 73.64
16 INT2466 Positive_regulation of SGOL1 1 0.07 0.1 0.52 70.48
17 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6 70.40
18 INT19995 Gene_expression of Prph 16 0.75 8.11 5.52 69.12
19 INT15307 Regulation of Mtor 27 0.48 4.7 9.34 68.00
20 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 66.96
21 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 58.52
22 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64 58.04
23 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 55.56
24 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 55.56
25 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 52.92
26 INT3439 Localization of Abat 1017 0.78 112.39 727.06 52.52
27 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11 48.88
28 INT208618 Positive_regulation of Nmb 2 0.18 0.71 0.22 46.44
29 INT112038 Positive_regulation of P2ry2 8 0.45 2.41 4.4 44.80
30 INT208615 Positive_regulation of Nmbr 1 0.27 0.06 0.2 43.80
31 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 43.44
32 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 43.44
33 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 43.44
34 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 40.12
35 INT15777 Gene_expression of Pvalb 66 0.78 25.97 26.13 40.12
36 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81 40.12
37 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02 39.36
38 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 36.08
39 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 36.00
40 INT174844 Binding of Fig4 81 0.41 18.03 12.87 35.04
41 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49 34.20
42 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 34.12
43 INT208611 Negative_regulation of Nmbr 1 0.23 0.59 1.44 33.36
44 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63 31.92
45 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 26.36
46 INT228676 Gene_expression of Rptor 1 0.29 0.32 0.41 25.28
47 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 25.00
48 INT74688 Regulation of Nos1 55 0.62 22.16 25.3 25.00
49 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9 24.80
50 INT208610 Regulation of Nmbr 1 0.24 0.1 0.03 22.44
51 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25 19.00
52 INT208614 Positive_regulation of Gene_expression of Nmbr 1 0.27 0.06 0.25 17.36
53 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 17.28
54 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 15.00
55 INT215091 Regulation of Localization of Gopc 6 0.27 1.18 1.2 14.20
56 INT173693 Localization of Gopc 249 0.65 70.49 38.81 13.72
57 INT243133 Positive_regulation of Positive_regulation of P2ry2 2 0.24 0.31 0.54 13.04
58 INT233482 Positive_regulation of Gene_expression of P2ry2 4 0.43 0.76 0.92 11.40
59 INT111680 Gene_expression of P2ry2 20 0.58 9.23 7.39 10.40
60 INT175834 Localization of SARS 6 0.39 6.23 0.17 8.28
61 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 8.12
62 INT233112 Gene_expression of Kcnk2 15 0.78 0.9 2.01 8.12
63 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
64 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
65 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
66 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 5.00
67 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
68 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
69 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
70 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 5.00
71 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 5.00
72 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
73 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
74 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 5.00
75 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 5.00
76 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 5.00
77 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
78 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 5.00
79 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
80 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85 5.00
81 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
82 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 5.00
83 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 5.00
84 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11 5.00
85 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83 5.00
86 INT7281 Binding of Sst 42 0.48 5.48 26.57 5.00
87 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01 5.00
88 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46 5.00
89 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
90 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86 5.00
91 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59 5.00
92 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 5.00
93 INT112207 Binding of Nav1 27 0.47 7.1 15.43 5.00
94 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01 5.00
95 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17 5.00
96 INT173272 Phosphorylation of Fig4 45 0.48 13.85 11.42 5.00
97 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84 5.00
98 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83 5.00
99 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52 5.00
100 INT80717 Gene_expression of Trpv3 20 0.72 10.05 9.96 5.00
101 INT134597 Binding of Trpa1 21 0.48 9.41 9.74 5.00
102 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62 5.00
103 INT9167 Binding of Adora1 6 0.40 0.53 6.9 5.00
104 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87 5.00
105 INT69499 Binding of Nos1 15 0.36 2.56 6.23 5.00
106 INT111683 Gene_expression of P2ry1 22 0.74 7.96 5.59 5.00
107 INT105216 Positive_regulation of Trpv2 9 0.61 4.12 4.93 5.00
108 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86 5.00
109 INT10694 Binding of Bche 19 0.48 8.03 4.85 5.00
110 INT130203 Gene_expression of P2ry4 14 0.50 8.79 4.82 5.00
111 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46 5.00
112 INT4739 Gene_expression of Calb1 16 0.78 2.83 4.08 5.00
113 INT55862 Negative_regulation of Calb1 7 0.57 1.4 3.85 5.00
114 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71 5.00
115 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43 5.00
116 INT55792 Regulation of Negative_regulation of Bche 11 0.57 1.78 3.21 5.00
117 INT85542 Negative_regulation of Calb2 5 0.38 5.4 3.18 5.00
118 INT99270 Negative_regulation of Gene_expression of Pvalb 5 0.08 5.74 3.15 5.00
119 INT106919 Regulation of Slc17a6 8 0.42 0.88 3.02 5.00
120 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97 5.00
121 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76 5.00
122 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55 5.00
123 INT96199 Negative_regulation of PGP 15 0.59 1.07 2.35 5.00
124 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28 5.00
125 INT15779 Negative_regulation of Pvalb 6 0.59 1.86 2.23 5.00
126 INT92542 Negative_regulation of Trpv2 8 0.59 1.54 2.15 5.00
127 INT129505 Regulation of Slc17a7 5 0.37 1.09 2.11 5.00
128 INT135258 Gene_expression of Pgp 4 0.47 1.28 1.96 5.00
129 INT81827 Positive_regulation of Kcnk2 7 0.70 0.42 1.79 5.00
130 INT102541 Binding of Tia1 3 0.26 0.68 1.64 5.00
131 INT96200 Gene_expression of PGP 9 0.76 0.79 1.63 5.00
132 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46 5.00
133 INT166764 Localization of Mtor 2 0.75 1.28 1.42 5.00
134 INT57524 Gene_expression of Sars 5 0.43 2.09 1.41 5.00
135 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21 5.00
136 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2 5.00
137 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16 5.00
138 INT233456 Gene_expression of P2ry6 5 0.66 1.74 1.04 5.00
139 INT228673 Negative_regulation of Fmr1 1 0.12 0.69 1.02 5.00
140 INT187635 Positive_regulation of SARDH 3 0.12 0.63 0.88 5.00
141 INT13543 Positive_regulation of LTC4S 5 0.58 2.26 0.88 5.00
142 INT233474 Positive_regulation of P2ry6 4 0.40 2.04 0.84 5.00
143 INT190958 Negative_regulation of Gene_expression of Calb1 5 0.41 2.15 0.77 5.00
144 INT228672 Binding of Fmr1 1 0.11 0.26 0.71 5.00
145 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71 5.00
146 INT166120 Gene_expression of Pla2g5 3 0.43 1.54 0.64 5.00
147 INT163777 Negative_regulation of Gene_expression of Calb2 2 0.34 1.39 0.58 5.00
148 INT143768 Negative_regulation of Positive_regulation of Trpm8 3 0.43 0.57 0.57 5.00
149 INT208612 Binding of Prph 2 0.12 0.54 0.57 5.00
150 INT166698 Localization of Vim 3 0.18 1.13 0.4 5.00
151 INT208608 Localization of Tia1 2 0.05 0.91 0.39 5.00
152 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38 5.00
153 INT141313 Positive_regulation of Kcnk10 2 0.41 0.69 0.37 5.00
154 INT228674 Protein_catabolism of Pgp 1 0.14 0.14 0.35 5.00
155 INT228660 Negative_regulation of Eif4ebp1 2 0.41 1.19 0.32 5.00
156 INT117786 Localization of Slc17a7 2 0.17 0 0.28 5.00
157 INT228662 Gene_expression of Eif4ebp1 2 0.65 0.91 0.26 5.00
158 INT83237 Negative_regulation of SHFM1 2 0.42 0.66 0.26 5.00
159 INT282054 Negative_regulation of Gene_expression of P2ry2 1 0.18 0.54 0.15 5.00
160 INT253783 Negative_regulation of Slc17a7 2 0.18 0 0.08 5.00
161 INT228669 Positive_regulation of Localization of Vim 1 0.12 0.34 0.07 5.00
162 INT208616 Positive_regulation of Binding of Prph 1 0.08 0 0.06 5.00
163 INT208619 Positive_regulation of Binding of Nmbr 1 0.27 0 0.06 5.00
164 INT212303 Positive_regulation of FANCE 1 0.04 0.06 0.03 5.00
165 INT212304 Regulation of Positive_regulation of FANCE 1 0.04 0.06 0.03 5.00
166 INT253781 Binding of Slc17a6 1 0.03 0 0 5.00
167 INT253782 Negative_regulation of Localization of Slc17a7 1 0.03 0 0 5.00
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