P:mu opioid receptor

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pChart

Pain Term
Category Molecule
Synonyms Mu Opioid Receptors, Mu-opioid Receptors
Pain Specific No
Documents 2145
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for mu opioid receptor. They are ordered first by their pain relevance and then by number of times they were reported for mu opioid receptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89 100.00
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65 100.00
3 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22 100.00
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15 100.00
5 INT259209 Binding of Glul and Flna 1 0.03 0 4.2 100.00
6 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7 100.00
7 INT259198 Oprm1 Negative_regulation of Binding of Oprm1 and Flna 1 0.00 0 2.64 100.00
8 INT259214 Oprm1 Negative_regulation of Binding of Flna and Flna 1 0.01 0 2.64 100.00
9 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66 100.00
10 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16 100.00
11 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67 100.00
12 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99 100.00
13 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26 100.00
14 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93 100.00
15 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31 100.00
16 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9 100.00
17 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03 100.00
18 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05 100.00
19 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05 100.00
20 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16 100.00
21 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55 100.00
22 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9 100.00
23 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33 100.00
24 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98 100.00
25 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65 100.00
26 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72 100.00
27 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12 100.00
28 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72 100.00
29 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63 100.00
30 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58 100.00
31 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08 100.00
32 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81 100.00
33 INT97012 Binding of CALM1 and OPRM1 1 0.18 0 0.82 100.00
34 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87 100.00
35 INT200325 Ahrr Regulation of Oprm1 1 0.00 0.09 0.49 100.00
36 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49 100.00
37 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45 100.00
38 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39 100.00
39 INT200329 Dbp Negative_regulation of Gene_expression of Oprm1 1 0.03 0.07 0.5 100.00
40 INT200345 Binding of Gtf3a and Negative_regulation of Gene_expression of Oprm1 1 0.01 0.05 0.46 100.00
41 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6 100.00
42 INT200336 Gtf3a Negative_regulation of Gene_expression of Oprm1 1 0.01 0 0.45 100.00
43 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7 100.00
44 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41 100.00
45 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41 100.00
46 INT200339 Preb Negative_regulation of Gene_expression of Oprm1 1 0.02 0.08 0.4 100.00
47 INT200303 Oprm1 Negative_regulation of Rorb 1 0.00 0.1 0.39 100.00
48 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39 100.00
49 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39 100.00
50 INT200356 Binding of Rest and Sp3 Regulation of Rorb 1 0.00 0.07 0.38 100.00
51 INT200355 Binding of Rest and Sp3 Regulation of Oprm1 1 0.22 0.07 0.38 100.00
52 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38 100.00
53 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38 100.00
54 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38 100.00
55 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 100.00
56 INT207545 U Regulation of Gene_expression of Oprm1 1 0.00 0.25 0.47 100.00
57 INT137139 ITIH4 Positive_regulation of OPRM1 1 0.37 0.67 0.72 100.00
58 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92 100.00
59 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53 100.00
60 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9 100.00
61 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94 100.00
62 INT95059 Binding of Oprm1 and Slc18a3 1 0.04 0 0.52 100.00
63 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23 100.00
64 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75 100.00
65 INT137138 ITIH4 Positive_regulation of Positive_regulation of OPRM1 1 0.42 0.55 0.59 100.00
66 INT65024 Binding of Oprm1 and Penk 1 0.03 0 0.93 100.00
67 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5 100.00
68 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19 100.00
69 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97 100.00
70 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97 100.00
71 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9 100.00
72 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59 100.00
73 INT137140 HIVEP1 Regulation of Gene_expression of OPRM1 1 0.25 0.69 0.66 100.00
74 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99 100.00
75 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64 100.00
76 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64 100.00
77 INT137143 HIVEP1 Positive_regulation of OPRM1 1 0.15 0.43 0.52 100.00
78 INT137145 HIVEP1 Regulation of OPRM1 1 0.10 0.7 0.64 100.00
79 INT200357 Binding of Oprm1 and Rest Negative_regulation of Rorb 1 0.00 0 0.64 100.00
80 INT200300 Binding of Nenf and Rorb 1 0.00 0 0.64 100.00
81 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64 100.00
82 INT200334 Binding of Oprm1 and Nenf 1 0.01 0 0.61 100.00
83 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57 100.00
84 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32 100.00
85 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06 100.00
86 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36 100.00
87 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7 100.00
88 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7 100.00
89 INT207544 Qsox1 Regulation of Oprm1 1 0.08 0.06 0.7 100.00
90 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 100.00
91 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6 100.00
92 INT200299 Binding of Rest and Rorb Negative_regulation of Rorb 1 0.00 0 0.23 100.00
93 INT207546 U Positive_regulation of Gene_expression of Oprm1 1 0.01 0.07 0.22 100.00
94 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24 100.00
95 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93 100.00
96 INT160794 Regulation of Binding of Pvalb and Mors1 1 0.02 0 0.52 100.00
97 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1 100.00
98 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08 100.00
99 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87 100.00
100 INT160795 Binding of Pvalb and Mors1 1 0.02 0 0.51 100.00
101 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81 100.00
102 INT160793 Regulation of Binding of Oprd1 and Pvalb 1 0.03 0 0.53 100.00
103 INT160792 Binding of Oprd1 and Pvalb 1 0.02 0 0.53 100.00
104 INT200340 Dbp Negative_regulation of Oprm1 1 0.03 0.06 0.2 100.00
105 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32 100.00
106 INT200343 Dbp Regulation of Gene_expression of Oprm1 1 0.02 0.07 0.18 100.00
107 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64 100.00
108 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35 100.00
109 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82 100.00
110 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07 100.00
111 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27 100.00
112 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26 100.00
113 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 100.00
114 INT96795 ITIH4 Positive_regulation of Gene_expression of OPRM1 1 0.49 0.17 0.76 100.00
115 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67 100.00
116 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71 100.00
117 INT200305 Rorb Positive_regulation of Gene_expression of Oprm1 1 0.00 0 0.13 100.00
118 INT200330 Gtf3a Positive_regulation of Gene_expression of Oprm1 1 0.01 0 0.13 100.00
119 INT200328 Sp3 Positive_regulation of Gene_expression of Oprm1 1 0.38 0 0.13 100.00
120 INT200338 Rest Positive_regulation of Gene_expression of Oprm1 1 0.36 0 0.13 100.00
121 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49 100.00
122 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15 100.00
123 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 1 0.01 0 1.1 100.00
124 INT200320 Binding of Sp3 and Negative_regulation of Gene_expression of Oprm1 1 0.35 0.4 0.1 100.00
125 INT200354 Binding of Rest and Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.34 0.4 0.1 100.00
126 INT104710 Em Positive_regulation of Rbm39 1 0.02 0.07 1.76 100.00
127 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76 100.00
128 INT63584 Oprm1 Positive_regulation of Hrasls 1 0.00 0 0.29 100.00
129 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44 100.00
130 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32 100.00
131 INT61052 Binding of Adarb1 and Negative_regulation of Gene_expression of Odc1 1 0.02 0 0.81 100.00
132 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76 100.00
133 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63 100.00
134 INT66890 Binding of PENK and Oprd1 1 0.05 0 0.45 100.00
135 INT30146 Binding of Adarb1 and Pdyn 1 0.01 0.17 1.91 100.00
136 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36 100.00
137 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31 100.00
138 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27 100.00
139 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27 100.00
140 INT134584 Arrb2 Regulation of Arrb2 Regulation of Oprm1 1 0.19 0.62 1.07 100.00
141 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06 100.00
142 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1 100.00
143 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99 100.00
144 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99 100.00
145 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96 100.00
146 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74 100.00
147 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7 100.00
148 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68 100.00
149 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64 100.00
150 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63 100.00
151 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59 100.00
152 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57 100.00
153 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55 100.00
154 INT73056 Binding of Hrh1 and Adarb1 1 0.00 0.25 0.49 100.00
155 INT31818 Negative_regulation of Binding of Sst and Oprm1 1 0.26 0.3 0.48 100.00
156 INT31817 Positive_regulation of Binding of Sst and Oprm1 1 0.30 0.3 0.48 100.00
157 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
158 INT31816 Binding of Sst and Oprm1 1 0.22 0.3 0.48 100.00
159 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48 100.00
160 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
161 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48 100.00
162 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48 100.00
163 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 0.02 0 0.42 100.00
164 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 0.00 0 0.42 100.00
165 INT93201 Positive_regulation of Binding of IGHG3 and OPRM1 1 0.02 0 0.35 100.00
166 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33 100.00
167 INT98379 Regulation of Binding of Pomc and Oprd1 1 0.01 0.35 0.23 100.00
168 INT98380 Binding of Pomc and Oprd1 1 0.02 0.35 0.23 100.00
169 INT104089 Vta1 Negative_regulation of Abat 1 0.14 0 1.03 99.98
170 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64 99.96
171 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74 99.96
172 INT75992 Binding of Pvalb and Lgals3 1 0.00 0 0.56 99.92
173 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5 99.90
174 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98 99.84
175 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1 99.82
176 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63 99.76
177 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67 99.68
178 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 0.03 0.35 0.57 99.68
179 INT299264 PTPN3 Negative_regulation of VEGFA Positive_regulation of PI3 1 0.03 0.12 0.05 99.68
180 INT141426 ANTXRL Negative_regulation of ADCY1 1 0.00 0.41 0.11 99.64
181 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33 99.60
182 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67 99.56
183 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67 99.56
184 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32 99.48
185 INT61051 Pomc Negative_regulation of Odc1 1 0.22 0 0.54 99.36
186 INT52478 Binding of Adarb1 and Ift172 1 0.00 0 0.62 99.32
187 INT29382 Positive_regulation of gp Regulation of Mme 1 0.02 0 0.65 99.24
188 INT29381 gp Regulation of Mme 1 0.01 0 0.65 99.24
189 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65 99.12
190 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96 99.08
191 INT67014 Penk Regulation of Regulation of Cfp 1 0.24 0 0.61 99.04
192 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42 99.02
193 INT34444 Binding of Oprl1 and Ptprg 4 0.03 0.18 4.58 99.00
194 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24 98.88
195 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1 98.80
196 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63 98.80
197 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2 98.78
198 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6 98.78
199 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 98.64
200 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75 98.64

Single Events

The table below shows the top 200 pain related interactions that have been reported for mu opioid receptor. They are ordered first by their pain relevance and then by number of times they were reported in mu opioid receptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
2 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
3 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
4 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
5 INT221172 Binding of Flna 32 0.42 1.37 51.59 100.00
6 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 100.00
7 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
8 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 100.00
9 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 100.00
10 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
11 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 100.00
12 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
13 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65 100.00
14 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 100.00
15 INT8733 Localization of Oprm1 61 0.75 7.55 64.61 100.00
16 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37 100.00
17 INT83419 Gene_expression of Mors1 57 0.68 12.11 63.66 100.00
18 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5 100.00
19 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
20 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75 100.00
21 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 100.00
22 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
23 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75 100.00
24 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 100.00
25 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27 100.00
26 INT1564 Localization of OPRM1 41 0.80 8.03 44.67 100.00
27 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
28 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
29 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
30 INT108726 Binding of Mors1 38 0.33 7.08 43.62 100.00
31 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25 100.00
32 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
33 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 100.00
34 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 100.00
35 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
36 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22 100.00
37 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95 100.00
38 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67 100.00
39 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
40 INT14137 Localization of Oprm1 56 0.81 2.88 36.09 100.00
41 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
42 INT88293 Localization of Mors1 25 0.39 2.18 28.72 100.00
43 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43 100.00
44 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67 100.00
45 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78 100.00
46 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 100.00
47 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95 100.00
48 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45 100.00
49 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
50 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
51 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15 100.00
52 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66 100.00
53 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
54 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07 100.00
55 INT87794 Positive_regulation of Mors1 19 0.38 4.74 20.23 100.00
56 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69 100.00
57 INT221168 Localization of Flna 1 0.58 0.05 4.05 100.00
58 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 100.00
59 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 100.00
60 INT18429 Localization of Hps4 8 0.31 1.23 9.01 100.00
61 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
62 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 100.00
63 INT104688 Positive_regulation of Gene_expression of Mors1 8 0.15 1.22 8.72 100.00
64 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11 100.00
65 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79 100.00
66 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29 100.00
67 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 100.00
68 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
69 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
70 INT5791 Positive_regulation of Positive_regulation of Rbm39 13 0.25 1.61 9.88 100.00
71 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 100.00
72 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67 100.00
73 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 100.00
74 INT103666 Regulation of Mors1 20 0.28 3.6 18.86 100.00
75 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 100.00
76 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66 100.00
77 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73 100.00
78 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 100.00
79 INT63383 Binding of Cnr1 77 0.48 22.28 44.61 100.00
80 INT124144 Negative_regulation of Mors1 21 0.41 2.87 24.71 100.00
81 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51 100.00
82 INT81608 Gene_expression of Col11a1 13 0.15 1.58 6.87 100.00
83 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21 100.00
84 INT8691 Localization of Insr 85 0.80 9.27 30.32 100.00
85 INT5770 Binding of Rbm39 88 0.41 13.23 55.5 100.00
86 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77 100.00
87 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9 100.00
88 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78 100.00
89 INT31905 Positive_regulation of Binding of Oprd1 21 0.66 3.31 18.44 100.00
90 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 100.00
91 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
92 INT129374 Negative_regulation of Regulation of Oprm1 3 0.43 0.58 1.18 100.00
93 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
94 INT25146 Negative_regulation of Positive_regulation of Glul 5 0.43 0.91 4.53 100.00
95 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38 100.00
96 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4 100.00
97 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96 100.00
98 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08 100.00
99 INT79955 Localization of Cnr1 26 0.81 8.44 19.06 100.00
100 INT13290 Binding of Atxn2l 34 0.18 1.86 28.16 100.00
101 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48 100.00
102 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 100.00
103 INT64671 Gene_expression of NISCH 10 0.69 2.19 6.9 100.00
104 INT91357 Regulation of Dnm2 5 0.61 0 11.06 100.00
105 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51 100.00
106 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
107 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 100.00
108 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 100.00
109 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35 100.00
110 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11 100.00
111 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54 100.00
112 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
113 INT21072 Localization of Adarb1 26 0.69 2.76 17.95 100.00
114 INT4153 Binding of Insrr 109 0.40 17.99 72.15 100.00
115 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22 100.00
116 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 100.00
117 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55 100.00
118 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
119 INT53134 Localization of Kcnj3 2 0.79 0 1.67 100.00
120 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57 100.00
121 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
122 INT97021 Gene_expression of PTPRH 2 0.02 0 0.86 100.00
123 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 100.00
124 INT39948 Binding of FLNA 45 0.42 58.05 4.27 100.00
125 INT5300 Regulation of Insr 54 0.60 11.33 29.26 100.00
126 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44 100.00
127 INT15777 Gene_expression of Pvalb 66 0.78 25.97 26.13 100.00
128 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 100.00
129 INT1295 Binding of Pomc 85 0.48 12.92 42.8 100.00
130 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 100.00
131 INT7565 Transcription of Pomc 69 0.72 14.46 27.41 100.00
132 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 100.00
133 INT22205 Gene_expression of CCT6A 7 0.29 0.86 6.63 100.00
134 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 100.00
135 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47 100.00
136 INT72216 Regulation of Positive_regulation of PRKCA 9 0.37 1.36 3.26 100.00
137 INT6765 Localization of Oprl1 49 0.81 5.11 28.87 100.00
138 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31 100.00
139 INT259222 Positive_regulation of Binding of Glul 1 0.05 0 1.39 100.00
140 INT25057 Positive_regulation of Hmmr 14 0.28 5.09 9.63 100.00
141 INT68812 Regulation of Regulation of Oprm1 5 0.40 0.16 3.28 100.00
142 INT19580 Binding of Pag1 24 0.30 15.13 20.88 100.00
143 INT127341 Gene_expression of Gpm6a 44 0.75 3.67 13.32 100.00
144 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78 100.00
145 INT200278 Gene_expression of Preb 2 0.51 0.08 0.86 100.00
146 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 100.00
147 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 100.00
148 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
149 INT8731 Regulation of Localization of Oprm1 3 0.43 0.25 3.4 100.00
150 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 100.00
151 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 100.00
152 INT6065 Localization of GRIN1 15 0.74 3.15 9.81 100.00
153 INT110676 Positive_regulation of Binding of Mors1 3 0.44 0.38 5.9 100.00
154 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71 100.00
155 INT105997 Positive_regulation of Protein_catabolism of Oprm1 2 0.66 0.41 1.45 100.00
156 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96 100.00
157 INT8363 Localization of Nts 135 0.81 14.29 61.71 100.00
158 INT128862 Positive_regulation of Gene_expression of KIR2DS2 1 0.03 0.35 0.86 100.00
159 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85 100.00
160 INT72219 Gene_expression of METTL3 45 0.24 9.58 7.61 100.00
161 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72 100.00
162 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94 100.00
163 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 100.00
164 INT46646 Localization of FLNA 19 0.73 18.83 2.53 100.00
165 INT79020 Regulation of Binding of Fos 3 0.45 1.2 2.1 100.00
166 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37 100.00
167 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 100.00
168 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95 100.00
169 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59 100.00
170 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
171 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 100.00
172 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 100.00
173 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
174 INT2366 Binding of Cck 192 0.48 30.64 163.46 100.00
175 INT35786 Negative_regulation of Negative_regulation of OPRM1 2 0.33 0.91 1.1 100.00
176 INT64712 Localization of Ngfr 4 0.78 1.19 1.91 100.00
177 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65 100.00
178 INT3034 Localization of Ngf 126 0.81 50.81 72.84 100.00
179 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92 100.00
180 INT79502 Gene_expression of Pvalb 26 0.78 2.83 7.46 100.00
181 INT21435 Positive_regulation of Negative_regulation of Adarb1 7 0.39 3.13 6.5 100.00
182 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 100.00
183 INT147700 Positive_regulation of Gene_expression of Col11a1 1 0.01 0 0.39 100.00
184 INT64775 Binding of Kcnj3 1 0.32 0 0.65 100.00
185 INT4803 Transcription of Penk 435 0.72 59.09 182.4 100.00
186 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27 100.00
187 INT7281 Binding of Sst 42 0.48 5.48 26.57 100.00
188 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49 100.00
189 INT26866 Gene_expression of U 4 0.59 0.59 4.25 100.00
190 INT111359 Localization of Cnr1 55 0.81 11.25 27.41 100.00
191 INT72215 Regulation of Gene_expression of METTL3 2 0.08 0.25 1.04 100.00
192 INT143186 Positive_regulation of Regulation of Mors1 2 0.19 0.36 2.28 100.00
193 INT68443 Positive_regulation of METTL3 9 0.12 3.54 2.39 100.00
194 INT72218 Regulation of METTL3 5 0.08 1.62 1.14 100.00
195 INT92123 Gene_expression of Ccr1 3 0.74 3.17 3.13 100.00
196 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65 100.00
197 INT6239 Regulation of Regulation of Oprd1 7 0.45 0.34 7.26 100.00
198 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31 100.00
199 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68 100.00
200 INT104687 Positive_regulation of Positive_regulation of Mors1 3 0.33 0 1.8 100.00
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