P:nMDA receptor antagonist

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pChart

Pain Term
Category Drug class
Synonyms NMDA Receptor Antagonists
Pain Specific No
Documents 1087
Hot Single Events 200
Hot Interactions 42

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for nMDA receptor antagonist. They are ordered first by their pain relevance and then by number of times they were reported for nMDA receptor antagonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37 100.00
2 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11 100.00
3 INT149006 RPL7AP5 Negative_regulation of Phosphorylation of Ephb1 1 0.00 0.22 0.45 100.00
4 INT149005 RPL7AP5 Negative_regulation of Ephb1 1 0.00 0.21 0.44 100.00
5 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 99.60
6 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63 99.60
7 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35 99.60
8 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08 99.60
9 INT146590 Positive_regulation of Ppp1r1b Regulation of Pdyn 1 0.45 0.43 0.09 99.38
10 INT146589 Ppp1r1b Regulation of Pdyn 1 0.26 0.43 0.09 99.22
11 INT146591 Negative_regulation of Ppp1r1b Regulation of Pdyn 1 0.42 0.43 0.09 99.22
12 INT104016 RPGR Positive_regulation of Gene_expression of FOS 1 0.16 0 0.43 98.84
13 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21 98.64
14 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45 97.20
15 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 97.04
16 INT242763 Olr1746 Negative_regulation of Nos1 1 0.02 0.97 0.26 96.20
17 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4 96.18
18 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13 96.08
19 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 96.08
20 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 94.84
21 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12 94.84
22 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42 94.56
23 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02 93.92
24 INT146375 Sds Negative_regulation of Positive_regulation of Cysltr1 1 0.02 0.32 0.67 92.92
25 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39 92.28
26 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85 91.28
27 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19 90.96
28 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3 89.84
29 INT54491 Positive_regulation of Akr1d1 Positive_regulation of Binding of Jun and Rabep2 1 0.00 0 0.53 89.84
30 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 88.68
31 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53 88.48
32 INT193784 ITIH4 Positive_regulation of YWHAZ 1 0.04 1.21 0.34 88.08
33 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24 87.96
34 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16 86.16
35 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83 85.40
36 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87 85.28
37 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83 84.64
38 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79 82.92
39 INT142571 Pnoc Positive_regulation of Nos1 1 0.52 0.06 0.57 82.64
40 INT75823 Penk Positive_regulation of Gene_expression of Ddx5 1 0.03 0 0.92 81.80
41 INT75825 Ddx5 Positive_regulation of Gene_expression of Penk 1 0.03 0 0.92 81.80
42 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78 81.20
43 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35 79.92
44 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84 79.28
45 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28 79.28
46 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21 75.12
47 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36 75.00
48 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18 75.00
49 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 75.00
50 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54 71.36
51 INT121172 pcp Positive_regulation of Cfp 1 0.03 0.17 0.22 66.32
52 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5 64.88
53 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92 64.24
54 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19 64.16
55 INT86264 OPRK1 Negative_regulation of Gene_expression of HIVEP1 1 0.33 1.76 0.51 63.76
56 INT321917 1200011M11Rik Positive_regulation of DAO 1 0.01 0.9 0.27 63.32
57 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8 62.92
58 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95 62.80
59 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42 59.20
60 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28 59.00
61 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41 58.72
62 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54 58.12
63 INT274935 Ltp Positive_regulation of Localization of Ephb6 1 0.33 0 0.52 56.44
64 INT274938 Ltp Positive_regulation of Localization of Ephb2 1 0.25 0 0.52 56.44
65 INT111904 Binding of Gabrg1 and Insrr 1 0.02 0 0.74 55.76
66 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98 55.04
67 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61 55.04
68 INT329278 Vta1 Positive_regulation of Gene_expression of Fos 1 0.22 0 0.82 54.32
69 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09 51.76
70 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05 51.72
71 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02 50.84
72 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11 49.20
73 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49 43.32
74 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 42.80
75 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41 42.56
76 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92 41.60
77 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 40.96
78 INT295546 Ghrl Positive_regulation of Ghsr 3 0.39 0.09 0.77 38.36
79 INT353716 Ghrl Positive_regulation of Vta1 1 0.33 0 0.74 38.36
80 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 35.16
81 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06 35.04
82 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 34.16
83 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9 33.44
84 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 33.00
85 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 33.00
86 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 33.00
87 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76 32.32
88 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76 31.72
89 INT353718 Binding of Rbm39 and Ghsr 1 0.01 0 0.76 31.72
90 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85 25.64
91 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 25.00
92 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01 25.00
93 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09 25.00
94 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09 25.00
95 INT150350 Oprk1 Regulation of Pat 1 0.22 0.38 0.81 25.00
96 INT150348 Oprd1 Regulation of Pat 1 0.01 0.38 0.81 25.00
97 INT334358 Rvm Positive_regulation of Ephb1 1 0.17 0.98 0.82 24.56
98 INT334359 Negative_regulation of Rvm Positive_regulation of Ephb1 1 0.16 0.99 0.82 24.56
99 INT274936 Ephb2 Regulation of Gene_expression of Fos 1 0.15 0 0.36 22.00
100 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36 22.00
101 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36 22.00
102 INT274933 Ephb2 Regulation of Phosphorylation of Camk2a 1 0.29 0 0.36 22.00
103 INT255999 Binding of Ang and H7 1 0.00 0.38 0.54 15.60
104 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63 15.16
105 INT255997 Binding of Il1rn and H7 1 0.01 1.21 0.63 14.72
106 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72 11.92
107 INT340839 Binding of NOVA2 and Regulation of Cfp 1 0.02 0 0.32 9.08
108 INT256001 Ang Negative_regulation of Il1rn 1 0.11 0.25 0.27 9.04
109 INT256000 H7 Negative_regulation of Rnpep 1 0.00 0.26 0.27 8.60
110 INT255995 Binding of H7 and Negative_regulation of Rnpep 1 0.00 0.26 0.27 8.60
111 INT255996 H7 Negative_regulation of Il1rn 1 0.01 0.25 0.27 8.60
112 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 5.00
113 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 5.00
114 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
115 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 5.00
116 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 5.00
117 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6 5.00
118 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35 5.00
119 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24 5.00
120 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
121 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
122 INT240658 Ngf Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.33 1.67 1.99 5.00
123 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85 5.00
124 INT334343 GRP Regulation of Binding of GRP and Helt 1 0.02 0 1.81 5.00
125 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81 5.00
126 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 5.00
127 INT334345 Binding of GRP and Helt 1 0.02 0 1.79 5.00
128 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74 5.00
129 INT353717 Binding of Ghrl and Vta1 1 0.15 0 1.68 5.00
130 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 5.00
131 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 5.00
132 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 0.04 0.49 1.53 5.00
133 INT334347 GRP Positive_regulation of Localization of Gabrg1 1 0.19 0 1.5 5.00
134 INT356233 Slc32a1 Positive_regulation of Gabrg1 1 0.17 1.6 1.44 5.00
135 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42 5.00
136 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42 5.00
137 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4 5.00
138 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4 5.00
139 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34 5.00
140 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31 5.00
141 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
142 INT239640 Sst Positive_regulation of Ltp 1 0.04 0.23 1.26 5.00
143 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23 5.00
144 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23 5.00
145 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23 5.00
146 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 5.00
147 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 5.00
148 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 5.00
149 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 5.00
150 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 5.00
151 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
152 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 5.00
153 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12 5.00
154 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12 5.00
155 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1 5.00
156 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09 5.00
157 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 5.00
158 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06 5.00
159 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06 5.00
160 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06 5.00
161 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 5.00
162 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04 5.00
163 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01 5.00
164 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01 5.00
165 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01 5.00
166 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97 5.00
167 INT240457 Binding of Ppyr1 and Grina 1 0.06 0.42 0.96 5.00
168 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
169 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
170 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
171 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 5.00
172 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93 5.00
173 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92 5.00
174 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92 5.00
175 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91 5.00
176 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89 5.00
177 INT218062 Abat Negative_regulation of Ctse 1 0.03 0.25 0.89 5.00
178 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88 5.00
179 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
180 INT184916 Binding of da and Th 1 0.09 1.22 0.87 5.00
181 INT353719 Rbm39 Regulation of Localization of Vta1 1 0.01 0 0.84 5.00
182 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
183 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83 5.00
184 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 5.00
185 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81 5.00
186 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79 5.00
187 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79 5.00
188 INT239638 Sst Regulation of Fig4 1 0.12 0.39 0.78 5.00
189 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77 5.00
190 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77 5.00
191 INT184918 da Positive_regulation of Negative_regulation of Th 1 0.14 0.14 0.77 5.00
192 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77 5.00
193 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77 5.00
194 INT170369 Binding of Car2 and Nono 1 0.01 0 0.76 5.00
195 INT343599 Gys1 Regulation of Tst 1 0.01 0 0.75 5.00
196 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73 5.00
197 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72 5.00
198 INT334348 GRP Regulation of Helt 1 0.01 0 0.72 5.00
199 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.68 0.71 5.00
200 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for nMDA receptor antagonist. They are ordered first by their pain relevance and then by number of times they were reported in nMDA receptor antagonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
2 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 100.00
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 100.00
4 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 100.00
5 INT48883 Negative_regulation of GRIN3B 19 0.54 14.53 11.5 100.00
6 INT25915 Negative_regulation of RPL7AP5 9 0.38 3.56 8.5 100.00
7 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 100.00
8 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36 100.00
9 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75 100.00
10 INT341244 Gene_expression of Gm1330 2 0.15 0 2.87 100.00
11 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95 100.00
12 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78 100.00
13 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66 100.00
14 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 100.00
15 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
16 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
17 INT341245 Negative_regulation of Gene_expression of Gm1330 2 0.09 0 1.98 100.00
18 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
19 INT68467 Regulation of Regulation of Pdpk1 1 0.05 0.09 0.96 100.00
20 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 100.00
21 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 100.00
22 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 100.00
23 INT97891 Gene_expression of Ghrl 108 0.77 24.85 9.7 100.00
24 INT323462 Regulation of Gene_expression of Ghrl 2 0.27 0.15 1 100.00
25 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38 100.00
26 INT36726 Regulation of Gene_expression of Ltp 14 0.46 4.81 7.05 100.00
27 INT83505 Binding of AP-5 2 0.10 0.35 1.19 100.00
28 INT7777 Gene_expression of AP-5 3 0.22 0.08 1 100.00
29 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 100.00
30 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 100.00
31 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11 100.00
32 INT137532 Negative_regulation of HEY2 1 0.31 1.69 3.18 100.00
33 INT123978 Binding of GRIA1 3 0.41 3.5 2.62 100.00
34 INT121435 Negative_regulation of Gene_expression of P2rx1 3 0.43 1.82 2.21 100.00
35 INT121433 Gene_expression of Olfr801 1 0.03 1.28 1.8 100.00
36 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 99.98
37 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13 99.98
38 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99 99.96
39 INT88212 Negative_regulation of AP-5 2 0.09 0.28 2.57 99.96
40 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4 99.96
41 INT121436 Regulation of Olfr801 1 0.02 1.27 1.81 99.96
42 INT121437 Negative_regulation of Olfr801 1 0.04 1.26 1.8 99.96
43 INT263568 Negative_regulation of Positive_regulation of Ddit3 1 0.47 0.98 0.08 99.96
44 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.92
45 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 99.92
46 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78 99.92
47 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.90
48 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 99.90
49 INT104432 Binding of RPL7AP5 1 0.19 1.18 1.27 99.88
50 INT169454 Binding of ATD 2 0.21 2.51 0.86 99.88
51 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 99.86
52 INT1045 Localization of LH 1211 0.81 87.04 456.25 99.84
53 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 99.84
54 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 99.84
55 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 99.84
56 INT2379 Positive_regulation of Localization of LH 349 0.70 27.86 144.53 99.84
57 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45 99.84
58 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04 99.84
59 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72 99.84
60 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.84
61 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17 99.84
62 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 99.84
63 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89 99.84
64 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 99.80
65 INT416 Regulation of LH 253 0.62 31.48 125.55 99.80
66 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 99.80
67 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05 99.80
68 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.78
69 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17 99.78
70 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.76
71 INT101537 Gene_expression of Vta1 19 0.50 1.88 20.76 99.76
72 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 99.76
73 INT6869 Positive_regulation of Car3 34 0.61 5.15 14.21 99.76
74 INT31111 Negative_regulation of Positive_regulation of Car3 4 0.38 0.52 2.91 99.76
75 INT245999 Regulation of Gene_expression of Vta1 2 0.27 0.1 2.06 99.76
76 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 99.76
77 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17 99.74
78 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49 99.74
79 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 99.72
80 INT353713 Negative_regulation of Gene_expression of Vta1 1 0.26 0 2.83 99.72
81 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59 99.68
82 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16 99.68
83 INT141166 Positive_regulation of Gene_expression of Ddit3 15 0.56 10.32 1.92 99.68
84 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01 99.68
85 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 99.68
86 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08 99.64
87 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.62
88 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 99.58
89 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 99.56
90 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 99.56
91 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 99.52
92 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 99.52
93 INT126575 Negative_regulation of Ppi-rs 21 0.14 12.94 3.2 99.52
94 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 99.52
95 INT2158 Negative_regulation of Positive_regulation of LH 41 0.58 4.52 17.75 99.52
96 INT148070 Positive_regulation of Ppi-rs 14 0.08 9.46 1.67 99.52
97 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91 99.50
98 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 99.48
99 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82 99.48
100 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.44
101 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 99.44
102 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 99.44
103 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.44
104 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 99.42
105 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 99.38
106 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 99.38
107 INT218698 Negative_regulation of Positive_regulation of Fig4 11 0.20 6.01 6.32 99.36
108 INT5426 Negative_regulation of RTCA 58 0.51 12.34 25.74 99.34
109 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 99.28
110 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 99.28
111 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 99.24
112 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77 99.24
113 INT4738 Regulation of Ppp1r1b 14 0.49 2.41 7.08 99.22
114 INT146588 Negative_regulation of Regulation of Ppp1r1b 1 0.36 0.85 0.18 99.22
115 INT129978 Negative_regulation of Gene_expression of NDOR1 1 0.05 0.96 1.17 99.22
116 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 99.22
117 INT67002 Negative_regulation of Regulation of Pdyn 2 0.43 0.43 2.2 99.22
118 INT111422 Positive_regulation of Regulation of CNR1 3 0.03 0.56 2.76 99.20
119 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 99.16
120 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 99.10
121 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6 99.06
122 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6 99.06
123 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7 99.06
124 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57 99.06
125 INT129989 Negative_regulation of Positive_regulation of Gria1 2 0.35 0.82 1.21 99.06
126 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.04
127 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.04
128 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 99.04
129 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.04
130 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 99.00
131 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 98.98
132 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 98.98
133 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68 98.92
134 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 98.92
135 INT131689 Localization of Vta1 8 0.48 0.57 7.64 98.92
136 INT78695 Regulation of Casp3 24 0.44 9.43 10.48 98.88
137 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2 98.88
138 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 98.88
139 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 98.88
140 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81 98.88
141 INT54477 Gene_expression of Rabep2 13 0.75 0.56 1.95 98.86
142 INT226106 Negative_regulation of Ghrl 12 0.40 3.98 5.39 98.84
143 INT65102 Regulation of Ntf4 3 0.43 0.05 3.42 98.84
144 INT323469 Negative_regulation of Localization of Ghrl 4 0.29 0.4 2.49 98.84
145 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 98.80
146 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6 98.76
147 INT129979 Regulation of Gene_expression of NDOR1 1 0.08 0.96 1.16 98.74
148 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 98.72
149 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 98.72
150 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14 98.70
151 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 98.64
152 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 98.64
153 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39 98.64
154 INT12030 Positive_regulation of Gene_expression of Car1 15 0.50 3.98 5.27 98.64
155 INT169711 Positive_regulation of Gpr35 10 0.50 5.63 0.87 98.64
156 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23 98.58
157 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 98.52
158 INT7032 Positive_regulation of Pdyn 94 0.66 26.51 58.83 98.52
159 INT26408 Negative_regulation of da 36 0.18 13.46 20.32 98.48
160 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 98.42
161 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69 98.42
162 INT16850 Negative_regulation of Localization of Gabrg1 73 0.51 8.28 47.89 98.40
163 INT101477 Binding of ADORA1 8 0.31 0.42 3.07 98.40
164 INT95341 Gene_expression of NDOR1 17 0.75 4.27 10.98 98.38
165 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 98.38
166 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 98.32
167 INT7920 Binding of Akr1d1 26 0.27 3.64 19.73 98.32
168 INT50420 Transcription of Grin1 30 0.71 13.21 18.28 98.28
169 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5 98.28
170 INT74592 Regulation of Transcription of Grin1 2 0.60 1.05 1.51 98.28
171 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92 98.28
172 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 98.26
173 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 98.24
174 INT224964 Localization of Ghrl 30 0.59 7.71 8.77 98.20
175 INT224947 Positive_regulation of Localization of Ghrl 3 0.34 0.48 1.4 98.20
176 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 98.16
177 INT66391 Negative_regulation of Ddx5 2 0.04 0 2.17 98.16
178 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89 98.16
179 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2 98.16
180 INT56439 Regulation of Positive_regulation of Slc1a1 3 0.32 1.65 1.47 98.16
181 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 98.12
182 INT49315 Localization of Gabrd 17 0.63 2.32 7.95 98.12
183 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 98.12
184 INT200873 Positive_regulation of Negative_regulation of Gopc 4 0.36 0.81 1.59 98.12
185 INT14506 Regulation of Sst 46 0.62 15.02 22.66 98.08
186 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 98.08
187 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 98.06
188 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 98.06
189 INT3439 Localization of Abat 1017 0.78 112.39 727.06 98.04
190 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1 98.04
191 INT20840 Negative_regulation of Car3 14 0.47 4.35 6.83 98.04
192 INT29845 Positive_regulation of Sds 11 0.62 3.69 6.63 97.96
193 INT60768 Negative_regulation of Pdc 5 0.48 1.5 2.67 97.96
194 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 97.96
195 INT85630 Positive_regulation of Tyr 11 0.56 3.07 2.31 97.96
196 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 97.92
197 INT6179 Binding of Oprk1 37 0.48 9.24 24.83 97.88
198 INT26248 Positive_regulation of Ptprg 12 0.40 1.42 9.48 97.86
199 INT20585 Gene_expression of Gfra1 39 0.77 26.94 26.69 97.84
200 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 97.84
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