P:pain insensitivity

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pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific Yes
Documents 56
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for pain insensitivity. They are ordered first by their pain relevance and then by number of times they were reported for pain insensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65 5.00
2 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
3 INT236489 Gtf3a Regulation of Pain1 1 0.00 0.52 0.56 5.00
4 INT236492 Gtf3a Regulation of SNRNP70 1 0.00 0.52 0.56 5.00
5 INT253929 Binding of Vcam1 and Cd99l2 1 0.00 0.61 0.13 5.00
6 INT253930 IFNA1 Positive_regulation of Cdc42ep3 1 0.00 0.65 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for pain insensitivity. They are ordered first by their pain relevance and then by number of times they were reported in pain insensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 95.88
2 INT48008 Negative_regulation of Pde6b 9 0.15 6.12 4.11 95.80
3 INT49701 Negative_regulation of Localization of Ngf 9 0.58 3.01 5.75 90.64
4 INT3034 Localization of Ngf 126 0.81 50.81 72.84 90.32
5 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 88.92
6 INT44608 Gene_expression of C2 45 0.75 15.84 5.05 87.52
7 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 85.44
8 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 80.32
9 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 79.60
10 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04 78.00
11 INT35407 Positive_regulation of C2 25 0.69 7.74 2.59 71.76
12 INT116655 Binding of NAA50 3 0.36 1.93 0.78 67.52
13 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 67.16
14 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 58.40
15 INT253922 Gene_expression of Otc 13 0.17 1.21 0.73 37.64
16 INT85767 Gene_expression of Scn9a 11 0.76 9.27 2.74 31.20
17 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
18 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 5.00
19 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
20 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 5.00
21 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 5.00
22 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 5.00
23 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
24 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
25 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 5.00
26 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
27 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
28 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 5.00
29 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
30 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 5.00
31 INT8534 Localization of Pax3 85 0.59 28.71 82.82 5.00
32 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 5.00
33 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 5.00
34 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 5.00
35 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
36 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
37 INT21737 Binding of MC1R 129 0.48 45.45 56.54 5.00
38 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 5.00
39 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 5.00
40 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 5.00
41 INT1564 Localization of OPRM1 41 0.80 8.03 44.67 5.00
42 INT19078 Binding of Ngf 78 0.48 31.03 44.33 5.00
43 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 5.00
44 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97 5.00
45 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27 5.00
46 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 5.00
47 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 5.00
48 INT103262 Localization of Nav1 53 0.81 19.23 34.44 5.00
49 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
50 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
51 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 5.00
52 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
53 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97 5.00
54 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
55 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 5.00
56 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2 5.00
57 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 5.00
58 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 5.00
59 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83 5.00
60 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 5.00
61 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53 5.00
62 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06 5.00
63 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 5.00
64 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 5.00
65 INT112207 Binding of Nav1 27 0.47 7.1 15.43 5.00
66 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 5.00
67 INT69311 Gene_expression of Scn10a 31 0.78 15.54 14.64 5.00
68 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
69 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35 5.00
70 INT113490 Gene_expression of SCN9A 22 0.77 5.45 12.27 5.00
71 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11 5.00
72 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
73 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 5.00
74 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 5.00
75 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 5.00
76 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 5.00
77 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14 5.00
78 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09 5.00
79 INT13432 Positive_regulation of Klkb1 23 0.57 5.36 8.65 5.00
80 INT186273 Negative_regulation of Il13 33 0.46 22.88 8.65 5.00
81 INT79693 Regulation of Il4 30 0.51 21.96 8.6 5.00
82 INT156396 Localization of Tg(CAG-EGFP)D4Nagy 61 0.55 13.63 8.17 5.00
83 INT193663 Binding of Pain1 9 0.36 8.84 8.04 5.00
84 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45 5.00
85 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2 5.00
86 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 5.00
87 INT116229 Gene_expression of C1qa 28 0.77 18.53 5.35 5.00
88 INT97693 Gene_expression of REST 29 0.75 5.51 5.26 5.00
89 INT14126 Gene_expression of Grina 13 0.67 4.63 4.57 5.00
90 INT181395 Gene_expression of Ccl8 11 0.67 13.88 4.56 5.00
91 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3 5.00
92 INT186270 Regulation of Il13 13 0.43 11.58 4.19 5.00
93 INT82876 Regulation of IFNAR1 6 0.26 6.69 3.73 5.00
94 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68 5.00
95 INT134914 Binding of Gfap 21 0.37 8.25 3.67 5.00
96 INT111053 Positive_regulation of Positive_regulation of Nav1 4 0.46 2.97 3.53 5.00
97 INT46208 Negative_regulation of Scn10a 6 0.58 7.16 3.46 5.00
98 INT46691 Negative_regulation of SCN9A 5 0.50 1.37 3.44 5.00
99 INT96150 Gene_expression of H2-D1 44 0.27 16.23 3.4 5.00
100 INT28359 Gene_expression of Pdcd1 39 0.57 34.09 3.4 5.00
101 INT69313 Regulation of Scn10a 5 0.60 4.45 3.14 5.00
102 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77 5.00
103 INT179428 Binding of FANCE 5 0.34 3.65 2.74 5.00
104 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 5.00
105 INT236490 Positive_regulation of SCN11A 2 0.48 0.91 2.37 5.00
106 INT163063 Positive_regulation of C1qa 10 0.67 6.06 2.29 5.00
107 INT163064 Positive_regulation of Gene_expression of C1qa 9 0.67 6.51 2.29 5.00
108 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14 5.00
109 INT64075 Positive_regulation of Positive_regulation of Kcnma1 2 0.02 0.55 1.96 5.00
110 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94 5.00
111 INT184031 Gene_expression of Cish 14 0.49 9.82 1.86 5.00
112 INT299114 Localization of FANCE 5 0.53 3.37 1.49 5.00
113 INT113377 Positive_regulation of Localization of Nav1 2 0.70 0.23 1.46 5.00
114 INT236487 Positive_regulation of Gene_expression of Grina 2 0.08 1.77 1.45 5.00
115 INT179309 Regulation of Gene_expression of KCNMA1 8 0.39 2.36 1.36 5.00
116 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3 5.00
117 INT236488 Regulation of Regulation of Pain1 1 0.01 0.76 1.23 5.00
118 INT236485 Negative_regulation of Regulation of Pain1 1 0.01 0.76 1.23 5.00
119 INT253925 Positive_regulation of Gene_expression of Pdcd1 5 0.06 5.03 1.08 5.00
120 INT279821 Regulation of Scn9a 2 0.44 2.79 0.83 5.00
121 INT150108 Positive_regulation of Gene_expression of Slc37a4 5 0.35 2.09 0.83 5.00
122 INT284844 Regulation of Localization of Nav1 2 0.59 0.18 0.83 5.00
123 INT203035 Gene_expression of Pdcd1lg2 4 0.58 1.97 0.74 5.00
124 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69 5.00
125 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68 5.00
126 INT236356 Positive_regulation of Binding of Gfap 4 0.44 3.2 0.67 5.00
127 INT247954 Positive_regulation of Pdcd1 5 0.16 4.97 0.65 5.00
128 INT224635 Positive_regulation of Lgals3bp 3 0.07 2.31 0.58 5.00
129 INT221391 Localization of Sub1 1 0.06 0.18 0.49 5.00
130 INT341334 Negative_regulation of Localization of Nav1 1 0.41 0.22 0.42 5.00
131 INT210831 Gene_expression of Abca4 7 0.67 1.69 0.32 5.00
132 INT253917 Gene_expression of Rnf123 3 0.08 1.98 0.3 5.00
133 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29 5.00
134 INT253918 Positive_regulation of Gene_expression of Rnf123 1 0.07 1.61 0.25 5.00
135 INT253924 Positive_regulation of Gene_expression of Cish 2 0.22 1.67 0.25 5.00
136 INT226826 Gene_expression of Scn1b 5 0.57 0.52 0.22 5.00
137 INT341335 Gene_expression of Scn2b 1 0.41 0 0.22 5.00
138 INT253916 Binding of Cd99l2 1 0.02 0.61 0.12 5.00
139 INT253923 Binding of Trex1 1 0.29 1.59 0.1 5.00
140 INT184448 Binding of Furin 2 0.36 0.81 0.09 5.00
141 INT253928 Negative_regulation of Binding of Furin 1 0.41 0.82 0.09 5.00
142 INT253921 Positive_regulation of C4a 1 0.32 0.59 0.07 5.00
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