P:pregabalin

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific Yes
Documents 931
Hot Single Events 175
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for pregabalin. They are ordered first by their pain relevance and then by number of times they were reported for pregabalin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 99.92
2 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 98.74
3 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63 82.92
4 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 65.16
5 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 65.16
6 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 63.48
7 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73 46.48
8 INT97207 Binding of Gabrg1 and Ptar1 1 0.00 0.07 0.55 25.00
9 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 12.24
10 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
11 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
12 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
13 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
14 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34 5.00
15 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
16 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
17 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 5.00
18 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
19 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
20 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
21 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98 5.00
22 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88 5.00
23 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82 5.00
24 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 5.00
25 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 5.00
26 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 5.00
27 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 5.00
28 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61 5.00
29 INT334592 MRGPRD Positive_regulation of ABAT 1 0.03 0.32 0.54 5.00
30 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51 5.00
31 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48 5.00
32 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41 5.00
33 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35 5.00
34 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34 5.00
35 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
36 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
37 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
38 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
39 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 5.00
40 INT342688 Binding of Cap1 and Nav1 1 0.00 0.19 0.14 5.00
41 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14 5.00
42 INT352416 Ccl2 Positive_regulation of Ccr2 1 0.23 0.26 0.14 5.00
43 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 5.00
44 INT342692 Binding of Gopc and Nav1 1 0.02 0.15 0.1 5.00
45 INT342694 Binding of Pdzd2 and Gopc 1 0.03 0.15 0.1 5.00
46 INT342690 Binding of Sft2d3 and Pdzd2 1 0.00 0.15 0.09 5.00
47 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 5.00
48 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08 5.00
49 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 5.00
50 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 5.00
51 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05 5.00
52 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 5.00
53 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04 5.00
54 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for pregabalin. They are ordered first by their pain relevance and then by number of times they were reported in pregabalin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6437 Binding of YY1 154 0.47 26.3 90.46 100.00
2 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 100.00
3 INT351278 Regulation of FMOD 1 0.09 6.45 5.16 100.00
4 INT155988 Regulation of Localization of ABAT 5 0.24 2.19 6.59 100.00
5 INT100720 Gene_expression of CACNA2D2 2 0.46 0.68 2.08 100.00
6 INT164708 Regulation of Regulation of Scap 1 0.02 0.34 1.02 100.00
7 INT239103 Binding of PR@ 2 0.29 0.36 1.83 100.00
8 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 100.00
9 INT96071 Localization of PIAS1 6 0.71 4.44 3.79 100.00
10 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21 100.00
11 INT812 Localization of INS 1026 0.81 515.6 145.31 100.00
12 INT99339 Positive_regulation of Slc6a12 1 0.50 0.2 0.91 100.00
13 INT103875 Binding of Tmem132a 3 0.36 0 4.45 100.00
14 INT156763 Gene_expression of TMEM37 5 0.39 1.48 0.36 100.00
15 INT165737 Localization of RHD 1 0.01 0.08 0.26 100.00
16 INT165738 Localization of TRAPPC1 1 0.04 0.08 0.26 100.00
17 INT156762 Gene_expression of CLC 1 0.29 0.09 0.23 100.00
18 INT133375 Binding of Pdha1 1 0.07 3.09 7.07 99.98
19 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77 99.98
20 INT140201 Positive_regulation of Binding of Cacna2d3 1 0.69 0.62 1.07 99.98
21 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65 99.98
22 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65 99.92
23 INT73010 Gene_expression of Tmem132a 8 0.77 4.38 8.86 99.92
24 INT311488 Positive_regulation of Localization of RLS 1 0.29 0.79 2.38 99.90
25 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 99.84
26 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 99.84
27 INT178853 Regulation of LOC298116 1 0.00 0.34 1.68 99.84
28 INT164705 Regulation of Scap 1 0.02 0.33 0.95 99.84
29 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22 99.84
30 INT55148 Binding of Dll1 5 0.48 0.66 2.97 99.84
31 INT12444 Binding of Gabrd 26 0.48 4.7 11.23 99.82
32 INT99116 Binding of Cacna2d3 15 0.48 7.33 13.58 99.80
33 INT8724 Positive_regulation of Mln 21 0.66 14.12 6.17 99.80
34 INT8481 Regulation of PIAS1 4 0.45 0.47 3.44 99.80
35 INT264641 Binding of AES 25 0.42 18.56 6.98 99.76
36 INT25647 Negative_regulation of Binding of YY1 10 0.57 1.47 6.77 99.74
37 INT164707 Positive_regulation of Scap 1 0.04 0.41 1.15 99.72
38 INT164704 Positive_regulation of Calr 1 0.23 0.41 1.15 99.72
39 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28 99.72
40 INT261712 Regulation of GABRB3 6 0.09 3.03 3.14 99.72
41 INT19488 Localization of ABAT 56 0.69 21.51 50.56 99.68
42 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 99.68
43 INT152629 Positive_regulation of Bid 6 0.46 6.74 1.78 99.68
44 INT178851 Negative_regulation of Ica1l 1 0.02 0.34 1.73 99.66
45 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49 99.66
46 INT155989 Negative_regulation of Localization of ABAT 7 0.38 1.29 6.95 99.62
47 INT125242 Localization of RLS 15 0.64 15.87 4.99 99.60
48 INT262375 Binding of Fmod 1 0.20 12.37 10.1 99.58
49 INT140200 Regulation of Cacna2d3 4 0.45 1.48 2.53 99.56
50 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.54
51 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98 99.50
52 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49 99.48
53 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84 99.44
54 INT109124 Positive_regulation of TIMP3 8 0.61 5.57 5.72 99.40
55 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.36
56 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96 99.34
57 INT78316 Regulation of TGM6 3 0.16 3.09 0.95 99.32
58 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 99.28
59 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 99.26
60 INT81904 Positive_regulation of FDPS 5 0.67 2.83 0.85 99.26
61 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17 99.24
62 INT2212 Binding of Abat 89 0.48 18.36 63.99 99.20
63 INT2910 Regulation of Abat 169 0.62 36.95 153.53 99.20
64 INT4880 Regulation of MME 17 0.61 7.78 8.2 99.14
65 INT4822 Localization of Ca2 417 0.80 99.57 96.45 99.12
66 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.12
67 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 99.12
68 INT70193 Gene_expression of Slc6a12 10 0.78 3.73 5.39 99.12
69 INT12441 Positive_regulation of Gpr156 29 0.67 5.7 24.44 99.06
70 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 99.06
71 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72 99.02
72 INT222892 Binding of CACNA2D2 2 0.23 2.78 2.42 99.02
73 INT165736 Gene_expression of TRAPPC1 1 0.03 0.08 0.25 99.02
74 INT123787 Gene_expression of Bid 25 0.66 16 6.35 99.00
75 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 99.00
76 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.00
77 INT46112 Regulation of GAD1 15 0.52 11.09 8.37 98.96
78 INT334616 Positive_regulation of MRGPRD 1 0.63 0.26 0.81 98.96
79 INT334619 Positive_regulation of Gene_expression of MRGPRD 1 0.39 0.07 0.38 98.96
80 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 98.88
81 INT133374 Gene_expression of Pdha1 3 0.12 1.44 2.98 98.86
82 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 98.86
83 INT133373 Localization of Pdha1 1 0.12 0 1.02 98.72
84 INT148406 Binding of CAMK2D 1 0.03 0.09 1.19 98.72
85 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76 98.54
86 INT144689 Regulation of RCT 49 0.53 25.91 9.6 98.40
87 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 98.38
88 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56 98.38
89 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25 98.30
90 INT18621 Binding of ABAT 28 0.36 9.88 18.04 98.30
91 INT32178 Gene_expression of Sptbn1 2 0.16 0.9 1.46 98.16
92 INT334615 Gene_expression of MRGPRD 1 0.70 3.6 6.49 98.06
93 INT3439 Localization of Abat 1017 0.78 112.39 727.06 97.96
94 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 97.86
95 INT95167 Positive_regulation of DRGX 33 0.22 26.72 21.04 97.82
96 INT142688 Positive_regulation of SERBP1 1 0.14 0.9 1.1 97.82
97 INT61076 Gene_expression of RHD 9 0.65 3.52 1.39 97.82
98 INT189629 Negative_regulation of TIMP3 14 0.48 7.63 3.91 97.72
99 INT81415 Gene_expression of Gabrp 2 0.30 1.49 1.84 97.72
100 INT99342 Positive_regulation of Gene_expression of Gabrp 2 0.23 0.76 0.87 97.72
101 INT250978 Binding of FMOD 4 0.16 12.32 8.75 97.68
102 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 97.68
103 INT9906 Binding of CYP2E1 15 0.40 1.89 2.08 97.68
104 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 97.68
105 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 97.68
106 INT89701 Binding of CYP2A6 4 0.36 0.92 2.23 97.68
107 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73 97.68
108 INT258081 Protein_catabolism of ABAT 5 0.10 2.57 2.86 97.56
109 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 97.28
110 INT351296 Regulation of Maf 1 0.01 0.9 0.88 97.24
111 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 97.16
112 INT71406 Regulation of Dll1 3 0.35 0.79 4.44 97.04
113 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73 97.04
114 INT273132 Regulation of FDPS 1 0.31 1.28 0.33 96.80
115 INT45812 Protein_catabolism of Gabrg1 12 0.79 1.93 8.76 96.72
116 INT99343 Regulation of Slc6a12 3 0.62 1.01 2.41 96.72
117 INT5359 Protein_catabolism of Abat 12 0.62 5.11 8.54 96.66
118 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 96.60
119 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 96.48
120 INT281139 Phosphorylation of Ccr2 2 0.79 1.2 1.18 96.32
121 INT281141 Positive_regulation of Phosphorylation of Ccr2 2 0.49 1.2 1.18 96.32
122 INT280447 Negative_regulation of Positive_regulation of MOCS1 1 0.00 0.75 0.69 96.16
123 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 96.16
124 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 95.96
125 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 95.84
126 INT345378 Negative_regulation of Gene_expression of BPIFA4P 1 0.02 0.85 0.8 95.84
127 INT165841 Gene_expression of BPIFA4P 17 0.65 6.48 2.38 95.84
128 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 95.80
129 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 95.56
130 INT143218 Binding of Gpr156 6 0.48 0.41 4.5 95.48
131 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.20
132 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07 95.08
133 INT345377 Positive_regulation of Positive_regulation of TIMP3 1 0.37 0.09 1.29 94.68
134 INT99341 Negative_regulation of Slc6a12 6 0.57 1.15 2.27 94.24
135 INT151401 Localization of JAG1 4 0.65 1.88 0.58 94.20
136 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 93.60
137 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51 93.56
138 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 93.40
139 INT5489 Localization of CA2 172 0.80 39.46 33.56 93.40
140 INT164254 Gene_expression of Dnaja3 1 0.57 1.1 1.83 93.28
141 INT250980 Negative_regulation of FMOD 2 0.14 2.67 2.31 93.12
142 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77 93.04
143 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 91.72
144 INT142689 Positive_regulation of Transcription of DRGX 1 0.22 0.92 1.16 91.72
145 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47 91.56
146 INT134382 Positive_regulation of Transcription of Trpa1 2 0.46 2.48 1.71 91.56
147 INT142084 Positive_regulation of Kdm5d 22 0.29 5.88 3.17 91.48
148 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 91.32
149 INT134016 Transcription of DRGX 3 0.25 3.82 3 91.32
150 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 90.72
151 INT142691 Positive_regulation of Gene_expression of CACNA2D1 1 0.34 0.92 1.17 90.16
152 INT142687 Gene_expression of CACNA2D1 1 0.38 0.92 1.17 89.76
153 INT2886 Gene_expression of SCT 13 0.78 4.55 3.57 89.76
154 INT96132 Gene_expression of F10 10 0.58 6.99 1.24 89.24
155 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 89.20
156 INT35048 Localization of TNFSF14 5 0.68 3.12 0.66 88.24
157 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3 88.00
158 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 86.64
159 INT36148 Binding of GAD1 10 0.41 7.91 1.47 86.32
160 INT262373 Positive_regulation of Fmod 1 0.20 0.89 0.77 86.24
161 INT4786 Gene_expression of GHRL 7 0.78 7.94 1.76 86.20
162 INT64280 Positive_regulation of Ptger1 22 0.67 14.9 7.49 86.16
163 INT11246 Binding of Grin1 65 0.48 14.53 36.93 86.08
164 INT99340 Regulation of Regulation of Slc6a12 1 0.45 0.27 0.7 85.68
165 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 83.00
166 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 82.40
167 INT143886 Positive_regulation of SIRT6 1 0.00 0.17 0.25 82.40
168 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 81.80
169 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 81.36
170 INT49768 Positive_regulation of Kcnj5 58 0.41 11.89 16.02 81.28
171 INT132315 Positive_regulation of DLL1 6 0.67 3.4 2.45 80.88
172 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 80.80
173 INT250981 Gene_expression of FMOD 2 0.20 7.3 4.47 80.32
174 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 80.32
175 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 80.20
176 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 79.84
177 INT123784 Positive_regulation of Gene_expression of Bid 4 0.40 2.41 0.66 79.68
178 INT52180 Binding of Aes 38 0.42 23.16 6.7 79.36
179 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 79.20
180 INT94833 Gene_expression of FGF1 4 0.53 2.01 0.81 78.92
181 INT156373 Binding of Sv2a 4 0.39 1.54 2.3 78.04
182 INT134379 Binding of Trpa1 13 0.48 7.16 7.27 77.92
183 INT154825 Gene_expression of HBXIP 1 0.09 0.2 0.25 77.56
184 INT107074 Gene_expression of C5 14 0.75 9.87 3.64 76.56
185 INT282188 Positive_regulation of Transcription of Gapdh 1 0.09 0.06 0.15 76.36
186 INT36751 Gene_expression of ZMYND10 7 0.75 3.92 0.32 76.24
187 INT282187 Transcription of Gapdh 2 0.69 0.24 0.15 75.76
188 INT12608 Regulation of CNR1 62 0.60 24.36 36.02 75.56
189 INT111422 Positive_regulation of Regulation of CNR1 3 0.03 0.56 2.76 75.56
190 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 75.00
191 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 75.00
192 INT103874 Negative_regulation of Localization of Flvcr2 1 0.19 0 0.4 75.00
193 INT84284 Localization of Flvcr2 8 0.35 0.81 5.3 75.00
194 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 75.00
195 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 74.76
196 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5 74.32
197 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 74.04
198 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 74.04
199 INT6943 Positive_regulation of Gabrd 71 0.70 17.36 35.25 73.92
200 INT154565 Regulation of Positive_regulation of PIK3CD 2 0.09 1.59 0.45 73.32
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