P:pruritus

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pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific No
Documents 2242
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for pruritus. They are ordered first by their pain relevance and then by number of times they were reported for pruritus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16163 Pth Regulation of Gene_expression of Plast4 1 0.00 0.65 0.25 99.80
2 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38 99.72
3 INT159538 SERPINB1 Regulation of Gene_expression of CALCA 1 0.01 0.8 0.45 97.72
4 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65 97.48
5 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48 96.56
6 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06 96.56
7 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94 96.24
8 INT154538 SF Regulation of Gene_expression of PPY 1 0.11 1 0.14 90.96
9 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23 87.20
10 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 81.24
11 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04 78.48
12 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 78.32
13 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1 77.32
14 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 75.08
15 INT154539 SF Regulation of Protein_catabolism of PPY 1 0.12 0.85 0.11 74.80
16 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 73.20
17 INT97430 Binding of B2M and HLA-B 1 0.00 0.66 0.04 71.52
18 INT154537 SF Positive_regulation of Gene_expression of PPY 1 0.15 0.81 0.11 71.24
19 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35 69.52
20 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 64.72
21 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82 62.40
22 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41 62.40
23 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 62.24
24 INT304010 Afw1 Negative_regulation of Gene_expression of ISYNA1 1 0.00 0.27 0.1 62.16
25 INT280007 Binding of CLTC and PAEP 1 0.06 0.8 0.08 61.36
26 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 56.68
27 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 56.68
28 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5 55.40
29 INT131162 Binding of CD58 and Cd2 1 0.01 1.21 0.18 53.92
30 INT131163 Negative_regulation of Binding of CD58 and Cd2 1 0.01 0.6 0.09 53.92
31 INT280004 Binding of IFNA1 and CDIPT 1 0.01 0.74 0.08 52.72
32 INT280005 Binding of PAEP and CDIPT 1 0.01 0.74 0.08 52.40
33 INT106487 Gene_expression of CD177 Negative_regulation of Gene_expression of Mpl 1 0.02 1.74 0.04 25.00
34 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04 25.00
35 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 12.84
36 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03 5.68
37 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
38 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
39 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
40 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
41 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 5.00
42 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 5.00
43 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
44 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
45 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
46 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88 5.00
47 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88 5.00
48 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
49 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55 5.00
50 INT243276 Hrh4 Positive_regulation of Hrh3 1 0.25 0.78 0.52 5.00
51 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
52 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 5.00
53 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 5.00
54 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
55 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44 5.00
56 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
57 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
58 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 5.00
59 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39 5.00
60 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
61 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38 5.00
62 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38 5.00
63 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37 5.00
64 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35 5.00
65 INT353010 Binding of GJA8 and TNF 1 0.02 0.24 0.33 5.00
66 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29 5.00
67 INT243273 Hrh1 Positive_regulation of Pla2g1b 1 0.10 0.3 0.29 5.00
68 INT243280 Hrh1 Positive_regulation of Pla2g5 1 0.22 0.3 0.29 5.00
69 INT243278 Positive_regulation of Hrh1 Positive_regulation of Pla2g1b 1 0.10 0.3 0.29 5.00
70 INT353009 Binding of GJA8 and VSIG1 1 0.00 0 0.29 5.00
71 INT243274 Positive_regulation of Hrh1 Positive_regulation of Pla2g5 1 0.22 0.3 0.29 5.00
72 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26 5.00
73 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25 5.00
74 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25 5.00
75 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24 5.00
76 INT277995 TNF Positive_regulation of Gene_expression of Tnfrsf1a 1 0.03 1.48 0.22 5.00
77 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 5.00
78 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22 5.00
79 INT277996 TNF Positive_regulation of Tnfrsf1a 1 0.03 1.48 0.22 5.00
80 INT306714 IL23A Positive_regulation of TNF 1 0.29 0.5 0.21 5.00
81 INT306746 Il12a Positive_regulation of TNF 1 0.24 0.5 0.21 5.00
82 INT295434 BRD2 Positive_regulation of Gene_expression of GNRH1 1 0.02 0.07 0.2 5.00
83 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2 5.00
84 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 5.00
85 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 5.00
86 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
87 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 5.00
88 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18 5.00
89 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17 5.00
90 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 5.00
91 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16 5.00
92 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16 5.00
93 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
94 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
95 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14 5.00
96 INT353011 GJA8 Regulation of USE1 1 0.00 0.35 0.13 5.00
97 INT341828 Binding of BTC and EGFR 1 0.22 0.95 0.12 5.00
98 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11 5.00
99 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11 5.00
100 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
101 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 5.00
102 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1 5.00
103 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1 5.00
104 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1 5.00
105 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 5.00
106 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09 5.00
107 INT351426 SEPT5 Regulation of HRAS 1 0.00 0.7 0.09 5.00
108 INT351425 HRAS Regulation of SEPT5 1 0.00 0.7 0.09 5.00
109 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09 5.00
110 INT297589 Binding of HAT1 and Il10 1 0.00 1.14 0.08 5.00
111 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08 5.00
112 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08 5.00
113 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 5.00
114 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08 5.00
115 INT275896 IFN1@ Positive_regulation of Gene_expression of TH1L 1 0.09 0.37 0.08 5.00
116 INT297559 Binding of IL6 and HAT1 1 0.00 1.13 0.08 5.00
117 INT352357 CPZ Positive_regulation of Gene_expression of HLA-DRA 1 0.12 0.13 0.07 5.00
118 INT352358 CD86 Positive_regulation of GOPC 1 0.30 0.13 0.07 5.00
119 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 5.00
120 INT205589 Binding of PPT2 and COQ2 1 0.04 1.02 0.07 5.00
121 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
122 INT283521 PREB Regulation of Fam89b 1 0.00 1.08 0.07 5.00
123 INT297562 TNF Positive_regulation of IFNA1 1 0.00 0.62 0.06 5.00
124 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06 5.00
125 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05 5.00
126 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 5.00
127 INT351010 ISG20 Positive_regulation of Transcription of IL2 1 0.31 0.46 0.05 5.00
128 INT351009 IL2RG Positive_regulation of Transcription of IL2 1 0.27 0.44 0.05 5.00
129 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 5.00
130 INT351012 IL2RB Positive_regulation of Gene_expression of IL15 1 0.10 0.42 0.05 5.00
131 INT351008 IL2RB Positive_regulation of Gene_expression of IL2 1 0.18 0.42 0.05 5.00
132 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 5.00
133 INT339020 SERPINA1 Negative_regulation of ELANE 1 0.07 0.59 0.05 5.00
134 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05 5.00
135 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 5.00
136 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04 5.00
137 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 5.00
138 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04 5.00
139 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
140 INT206685 IMPA1 Positive_regulation of HBS1L 1 0.00 0.24 0.04 5.00
141 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04 5.00
142 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 5.00
143 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 5.00
144 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 5.00
145 INT283462 Binding of DLAT and HLA-DRB1 1 0.07 1.06 0.03 5.00
146 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 5.00
147 INT351090 Phosphorylation of TXK Positive_regulation of EGFR 1 0.04 0.33 0 5.00
148 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0 5.00
149 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 5.00
150 INT266925 Regulation of Binding of EGFR and ERBB2 1 0.26 0.5 0 5.00
151 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0 5.00
152 INT241588 Binding of FAS and Fas 1 0.05 2.34 0 5.00
153 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0 5.00
154 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 5.00
155 INT274060 EGF Positive_regulation of EGFR Positive_regulation of TKT 1 0.08 1 0 5.00
156 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 5.00
157 INT297560 Binding of HSD11B1 and APOL1 1 0.04 0.88 0 5.00
158 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0 5.00
159 INT334498 Binding of IL13 and KLF1 1 0.00 0.63 0 5.00
160 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0 5.00
161 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 5.00
162 INT280006 Binding of CLTC and IFNA1 1 0.04 1.59 0 5.00
163 INT351013 PROK1 Regulation of ISG20 1 0.01 0.76 0 5.00
164 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0 5.00
165 INT352994 IPMK Regulation of VEGFA 1 0.00 0.66 0 5.00
166 INT294088 Binding of ERBB2 and ERBB4 2 0.13 0.88 0 5.00
167 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 5.00
168 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.00
169 INT205588 Binding of SNRNP70 and PPT2 1 0.03 0.26 0 5.00
170 INT229884 Gart Regulation of AKT1 1 0.02 0.4 0 5.00
171 INT331909 Binding of ALB and SPARC 1 0.06 2.01 0 5.00
172 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00
173 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0 5.00
174 INT274061 EGF Positive_regulation of EGFR Positive_regulation of TXK 1 0.06 1 0 5.00
175 INT284829 Binding of FCGR3A and Ighg1 1 0.00 0.13 0 5.00
176 INT284807 Binding of FCGR3A and IGHG3 1 0.01 0.08 0 5.00
177 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 5.00
178 INT327198 DBT Positive_regulation of Gene_expression of ESRRA 1 0.00 0.42 0 5.00
179 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0 5.00
180 INT297563 Binding of HSD11B1 and TBPL1 1 0.01 0.41 0 5.00
181 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0 5.00
182 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0 5.00
183 INT347225 Hck Regulation of Positive_regulation of Bcr 1 0.15 0.07 0 5.00
184 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 5.00
185 INT277897 EGF Positive_regulation of CALCRL 1 0.00 0.77 0 5.00
186 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0 5.00
187 INT318683 ARPP21 Negative_regulation of SET 1 0.00 0.1 0 5.00
188 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0 5.00
189 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0 5.00
190 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 5.00
191 INT277896 EGF Positive_regulation of TKT 1 0.02 0.76 0 5.00
192 INT277766 EGFR Regulation of Gene_expression of VEGFA 1 0.54 0.14 0 5.00
193 INT306764 Binding of Aes and ZMYND10 1 0.04 0.21 0 5.00
194 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 5.00
195 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 5.00
196 INT297558 Binding of APOL1 and SRA1 1 0.22 0.56 0 5.00
197 INT274062 EGF Positive_regulation of EGFR Positive_regulation of Positive_regulation of TXK 1 0.06 1 0 5.00
198 INT284184 Binding of Akt1 and Pdgfrb 1 0.00 0.14 0 5.00
199 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0 5.00
200 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for pruritus. They are ordered first by their pain relevance and then by number of times they were reported in pruritus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 100.00
2 INT182667 Binding of DLAT 11 0.31 40.75 2.8 99.98
3 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.96
4 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07 99.96
5 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.92
6 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 99.80
7 INT16161 Gene_expression of Plast4 1 0.00 0.64 0.25 99.80
8 INT41855 Localization of Grp 6 0.71 1.13 1.36 99.80
9 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.76
10 INT14884 Positive_regulation of Gene_expression of SFTPA1 32 0.25 20.37 26.09 99.70
11 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 99.70
12 INT8835 Localization of SFTPA1 65 0.68 32.81 38.65 99.70
13 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 99.68
14 INT69749 Binding of Tacr3 3 0.06 2.2 0.81 99.68
15 INT48877 Binding of Tacr1 16 0.43 5.26 8.04 99.68
16 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.64
17 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 99.64
18 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33 99.48
19 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 99.48
20 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 99.48
21 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.48
22 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59 99.48
23 INT15146 Regulation of Gene_expression of Vip 3 0.53 0.89 2.23 99.48
24 INT138018 Gene_expression of Il31 3 0.46 5.46 1.82 99.48
25 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.46
26 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.36
27 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.36
28 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.28
29 INT221844 Regulation of Binding of Il31 1 0.12 2.18 0.97 99.28
30 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 99.28
31 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 99.16
32 INT221846 Localization of NTF4 3 0.37 1.24 1.24 99.00
33 INT108932 Gene_expression of NTF4 4 0.40 1.65 1.58 99.00
34 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22 98.76
35 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 98.68
36 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 98.66
37 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 98.64
38 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.58
39 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 98.56
40 INT615 Regulation of Alb 66 0.62 33.43 15.33 98.50
41 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.48
42 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16 98.46
43 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 98.44
44 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 98.36
45 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 98.32
46 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 98.28
47 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.24
48 INT147606 Positive_regulation of TLR1 5 0.67 4.35 0.47 98.08
49 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 97.96
50 INT221845 Gene_expression of Klk7 2 0.04 1.71 0.82 97.88
51 INT221843 Positive_regulation of Gene_expression of Klk7 1 0.01 1.53 0.63 97.88
52 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69 97.80
53 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 97.72
54 INT48006 Negative_regulation of Oprk1 27 0.58 10.14 19.11 97.72
55 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 97.60
56 INT69572 Localization of Prnp 96 0.81 38.11 5.45 97.60
57 INT18843 Binding of H1 10 0.47 5.44 2.4 97.60
58 INT13752 Binding of Scn4a 24 0.36 5.68 14.16 97.52
59 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 97.52
60 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09 97.48
61 INT25991 Negative_regulation of Vip 11 0.53 6.76 4.64 97.44
62 INT77430 Negative_regulation of HTs 1 0.57 0.87 0.4 97.36
63 INT20210 Localization of Ngf 69 0.79 46.22 38.57 97.32
64 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35 97.28
65 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48 97.28
66 INT3167 Binding of KNG1 48 0.48 23.26 26.77 97.24
67 INT25353 Negative_regulation of F8 22 0.59 18.51 1.4 97.20
68 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33 97.12
69 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 97.12
70 INT26217 Binding of Calca 22 0.48 5.22 12.57 97.12
71 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 97.00
72 INT40084 Binding of HBS1L 8 0.36 9.15 0.69 96.96
73 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 96.84
74 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97 96.80
75 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06 96.76
76 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 96.68
77 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 96.58
78 INT92934 Gene_expression of GRPR 2 0.67 5.13 1.57 96.44
79 INT92935 Binding of GRPR 2 0.32 1.99 0.62 96.44
80 INT221842 Binding of Il31 1 0.10 2.09 0.94 96.40
81 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 96.40
82 INT72798 Binding of ADA 12 0.47 7.84 3.39 96.32
83 INT129015 Phosphorylation of Ngf 6 0.73 5.92 6.6 96.12
84 INT185181 Phosphorylation of Pth 2 0.64 1.51 0.3 96.08
85 INT115213 Regulation of SFTPA1 13 0.32 6.91 7.11 96.04
86 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 95.80
87 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 95.76
88 INT30312 Binding of Pdyn 30 0.37 4.2 18.23 95.68
89 INT201130 Localization of AES 31 0.63 25.45 5.12 95.68
90 INT11807 Gene_expression of Il2 266 0.78 112 64.97 95.60
91 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 95.60
92 INT170738 Binding of Icam1 23 0.37 25.49 4.09 95.60
93 INT14497 Gene_expression of GRP 82 0.78 17.67 32.27 95.60
94 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64 95.44
95 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 95.44
96 INT230 Positive_regulation of GGTLC1 14 0.68 11.78 1.55 95.44
97 INT39866 Gene_expression of RUNX1T1 2 0.65 1.75 0.1 95.44
98 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01 95.40
99 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 95.28
100 INT86446 Protein_catabolism of Lipg 9 0.50 3.52 1.25 95.10
101 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 94.88
102 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 94.88
103 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 94.84
104 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 94.68
105 INT1283 Positive_regulation of CD79B 1 0.67 0.69 0.14 94.68
106 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 94.52
107 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 94.48
108 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37 94.36
109 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 94.20
110 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 94.16
111 INT28894 Positive_regulation of PLK2 3 0.50 3.77 0.69 94.16
112 INT5320 Gene_expression of PTGFR 18 0.59 12.99 3.7 94.12
113 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 94.12
114 INT11657 Gene_expression of ALPI 11 0.71 5.13 0.74 94.12
115 INT39945 Binding of Dlat 27 0.32 14.95 3.88 94.08
116 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 93.98
117 INT1706 Negative_regulation of PCa 33 0.47 10.7 15.27 93.76
118 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 93.72
119 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 93.60
120 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 93.60
121 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16 93.52
122 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 93.44
123 INT60600 Binding of PSS 5 0.32 3.59 1.42 93.24
124 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 93.20
125 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 93.20
126 INT217393 Negative_regulation of Gene_expression of Mme 3 0.43 5.98 0.46 93.20
127 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 93.16
128 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 93.00
129 INT187528 Positive_regulation of Cq1 1 0.01 0.43 0.05 93.00
130 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 92.92
131 INT164975 Binding of ELN 6 0.35 6.38 0.64 92.88
132 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 92.88
133 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 92.88
134 INT64953 Negative_regulation of HLA-DRB1 9 0.58 5.15 0.56 92.64
135 INT8950 Gene_expression of Tacr3 12 0.76 0.97 4.07 92.56
136 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 92.32
137 INT83236 Localization of PGR 14 0.73 8.26 2.23 92.24
138 INT9378 Regulation of Positive_regulation of TRPV1 9 0.45 2.36 4.26 92.12
139 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12 91.92
140 INT335647 Gene_expression of OSMR 1 0.48 2.78 0.72 91.88
141 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 91.76
142 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 91.76
143 INT227416 Positive_regulation of DLAT 4 0.45 17.02 1.11 91.72
144 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 91.68
145 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 91.40
146 INT193154 Regulation of CRAMP1L 5 0.28 3.04 0.34 91.00
147 INT125711 Negative_regulation of TSS 6 0.51 3.64 0.12 90.88
148 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 90.84
149 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 90.80
150 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78 90.76
151 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 90.52
152 INT40638 Binding of HRH1 14 0.44 5.81 5.09 90.52
153 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 90.40
154 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 90.40
155 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 90.40
156 INT47674 Positive_regulation of Myoz1 21 0.54 4.37 3.57 90.24
157 INT134590 Localization of ADA 7 0.65 8.43 3.96 90.12
158 INT18853 Negative_regulation of APCS 13 0.57 4.51 2.3 89.80
159 INT347219 Positive_regulation of Dleu2 1 0.67 1.59 0.14 89.80
160 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 89.64
161 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 89.44
162 INT134326 Gene_expression of GSTT2 2 0.01 1.61 0.53 89.40
163 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 89.36
164 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 89.36
165 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 89.16
166 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81 89.04
167 INT172625 Regulation of HAT1 9 0.35 9.21 0.28 88.88
168 INT95924 Negative_regulation of Bczr1 1 0.00 1.5 0.47 88.72
169 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4 88.60
170 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 88.52
171 INT21782 Negative_regulation of B2M 11 0.46 5.49 1.92 88.40
172 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 87.80
173 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 87.52
174 INT8159 Binding of ELL 7 0.36 12.62 0.84 87.48
175 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 87.40
176 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 87.20
177 INT101693 Gene_expression of Ggt1 2 0.65 4.92 0.81 87.20
178 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 86.52
179 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 86.20
180 INT266627 Positive_regulation of Ugt1a2 3 0.04 5.54 0.56 86.20
181 INT84512 Binding of Myoz1 7 0.30 4.48 1.7 86.16
182 INT167882 Negative_regulation of Il31 1 0.07 1.35 0.34 86.04
183 INT283514 Localization of NR1I2 2 0.74 3.15 0.87 85.84
184 INT3034 Localization of Ngf 126 0.81 50.81 72.84 85.84
185 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41 85.84
186 INT105221 Gene_expression of NOL3 5 0.75 0.78 0.73 85.84
187 INT717 Regulation of F2 29 0.61 17.46 6.99 85.76
188 INT154541 Positive_regulation of SF 1 0.23 0.96 0.13 85.68
189 INT8668 Regulation of Positive_regulation of HSD11B1 6 0.44 6.36 0.35 85.52
190 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 85.44
191 INT20381 Localization of Il2 71 0.77 34.23 13.03 85.44
192 INT167883 Negative_regulation of Hrh4 1 0.03 1.35 0.34 85.44
193 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64 85.28
194 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 85.24
195 INT5008 Localization of Calca 204 0.81 80.35 125.16 85.24
196 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 84.88
197 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82 84.88
198 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25 84.88
199 INT74423 Localization of IL10 91 0.80 61.6 22.95 84.80
200 INT283508 Negative_regulation of Negative_regulation of DLAT 1 0.28 1.87 0.19 84.80
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