P:repetitive firing

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Pain Term
Category Process
Synonyms None
Pain Specific No
Documents 170
Hot Single Events 64
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for repetitive firing. They are ordered first by their pain relevance and then by number of times they were reported for repetitive firing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27 59.28
2 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 49.68
3 INT273791 Ntf3 Positive_regulation of Nfasc 1 0.01 0.18 0.09 36.28
4 INT273792 Cxcr2 Positive_regulation of Nfasc 1 0.08 0.29 0.17 30.04
5 INT88683 Pdyn Regulation of Pacsin1 1 0.00 0 0.31 25.16
6 INT251450 Binding of Dpp6 and Kcnc1 1 0.37 0.18 0.2 23.72
7 INT251451 Binding of Dpp6 and Dpp10 1 0.21 0.06 0 23.72
8 INT251453 Binding of Kcnc1 and Dpp10 1 0.20 0.18 0.18 23.36
9 INT243557 Binding of PSPH and SPECC1 1 0.01 1.19 0.12 7.04
10 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14 5.00
11 INT248184 Cxcl1 Positive_regulation of DRGX 1 0.02 1.25 0.97 5.00
12 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93 5.00
13 INT248187 Cxcl1 Regulation of NA 1 0.01 0.73 0.63 5.00
14 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47 5.00
15 INT292928 Olr717 Regulation of Grip2 1 0.00 0 0.37 5.00
16 INT251452 Binding of Car1 and Kcnc1 1 0.11 0 0.22 5.00
17 INT248182 Cxcl1 Regulation of Scn8a 1 0.05 0 0.22 5.00
18 INT230269 Negative_regulation of Binding of NA and Nav1 1 0.00 0 0.19 5.00
19 INT230270 Binding of NA and Nav1 1 0.00 0 0.19 5.00
20 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 5.00
21 INT287723 Oxt Regulation of Gene_expression of Plbd2 1 0.01 0.13 0.17 5.00
22 INT230604 OLIG2 Negative_regulation of IRX3 1 0.34 0.54 0.14 5.00
23 INT248185 Binding of Cxcr2 and DRGX 1 0.01 0 0.09 5.00
24 INT293471 Binding of Map2 and Fig4 1 0.03 0 0.08 5.00
25 INT193340 Binding of SHOX and LEFTY1 1 0.01 0 0 5.00
26 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0 5.00
27 INT193343 Binding of STAR and WASF1 1 0.04 0 0 5.00
28 INT193341 auditory Positive_regulation of CASP8AP2 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for repetitive firing. They are ordered first by their pain relevance and then by number of times they were reported in repetitive firing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT135032 Negative_regulation of SRF 1 0.49 0 1.03 100.00
2 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98 100.00
3 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63 100.00
4 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69 99.92
5 INT81207 Positive_regulation of Lth1 10 0.35 5.22 9.81 99.50
6 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77 98.92
7 INT223627 Negative_regulation of Positive_regulation of Mrgprd 1 0.55 0.69 0.71 98.88
8 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 98.68
9 INT248797 Positive_regulation of Mns1 2 0.09 0.4 0.76 98.56
10 INT148864 Localization of DRGX 11 0.17 7.67 8.36 98.54
11 INT23290 Negative_regulation of Slc12a6 5 0.05 1.4 1.46 98.48
12 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16 98.40
13 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49 98.40
14 INT143368 Positive_regulation of Mrgprd 6 0.65 2.88 3.1 98.32
15 INT16025 Gene_expression of Lth1 6 0.40 1.89 2.5 98.32
16 INT54234 Binding of Cd2 6 0.35 2.14 1.99 98.12
17 INT59671 Positive_regulation of Scn8a 7 0.39 1.88 5.92 98.00
18 INT97366 Regulation of Nav1 38 0.62 23.63 38.17 97.60
19 INT223618 Positive_regulation of Mrgpra1 1 0.64 1.04 1.07 97.16
20 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 97.12
21 INT166490 Localization of Msn 9 0.80 0.61 2.32 96.72
22 INT280862 Positive_regulation of Localization of Msn 1 0.35 0 0.3 96.72
23 INT223626 Gene_expression of Mrgpra1 1 0.56 1.08 1.09 96.60
24 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 96.52
25 INT106037 Gene_expression of PEPD 10 0.75 4.18 3.11 96.52
26 INT106039 Negative_regulation of Gene_expression of PEPD 5 0.56 1.37 1.18 96.52
27 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 96.16
28 INT11445 Positive_regulation of Slc12a6 11 0.31 3.29 3.6 96.04
29 INT110830 Negative_regulation of Mns1 2 0.34 0.91 1.64 96.00
30 INT106534 Gene_expression of Dock9 3 0.65 1.62 1.63 95.92
31 INT106533 Positive_regulation of Gene_expression of Dock9 1 0.49 0.33 0.65 95.92
32 INT195187 Positive_regulation of Msn 5 0.49 0.38 3.66 95.80
33 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 95.60
34 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 95.00
35 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2 95.00
36 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 94.84
37 INT4207 Regulation of Avp 267 0.62 63.72 115.33 94.80
38 INT8481 Regulation of PIAS1 4 0.45 0.47 3.44 94.64
39 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3 90.60
40 INT26054 Regulation of Gene_expression of Scn8a 7 0.08 2.86 4.49 90.60
41 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8 90.44
42 INT5430 Gene_expression of Scn8a 37 0.75 4.58 14.82 90.16
43 INT34425 Positive_regulation of Negative_regulation of NA 12 0.38 4.17 3.2 88.84
44 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 87.96
45 INT25738 Positive_regulation of Chrng 7 0.43 0.99 1.69 87.76
46 INT81208 Negative_regulation of Positive_regulation of Lth1 5 0.28 1.01 2.78 87.04
47 INT223620 Positive_regulation of Mrgprx2 1 0.02 0.54 0.53 86.80
48 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 86.52
49 INT81209 Negative_regulation of Lth1 3 0.28 0.97 1.94 86.40
50 INT67793 Binding of Pim3 1 0.03 0 0.4 85.52
51 INT71030 Binding of Mc1r 39 0.48 10.27 12.02 85.44
52 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 85.24
53 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9 84.80
54 INT30072 Positive_regulation of Clns1a 5 0.20 0.85 0.9 83.88
55 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37 83.36
56 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8 82.88
57 INT293463 Regulation of Kcnh1 1 0.45 0.06 0.26 82.52
58 INT78032 Regulation of Oxtr 12 0.62 0.72 1.09 82.48
59 INT287718 Gene_expression of Plbd2 1 0.03 0.36 1.38 81.24
60 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 81.20
61 INT247615 Binding of URI1 2 0.20 1.17 1.13 81.08
62 INT139546 Gene_expression of URI1 3 0.75 3 1.49 80.36
63 INT27132 Negative_regulation of Nfkbiz 8 0.59 0 2.22 80.24
64 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 80.08
65 INT28912 Positive_regulation of Cd2 3 0.50 0.48 0.41 80.00
66 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 79.44
67 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 79.00
68 INT164989 Positive_regulation of Mrgprx1 2 0.46 1.68 1.05 78.20
69 INT1539 Positive_regulation of MSMB 22 0.69 9.42 4.62 77.76
70 INT247619 Regulation of Positive_regulation of DRGX 1 0.03 1 0.97 77.40
71 INT451 Regulation of Oxt 142 0.62 22.07 69.42 76.60
72 INT95167 Positive_regulation of DRGX 33 0.22 26.72 21.04 76.56
73 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 76.56
74 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 75.44
75 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 75.40
76 INT47992 Gene_expression of Scn8a 14 0.78 4.15 3.83 73.44
77 INT195185 Regulation of Regulation of Msn 3 0.38 0.29 1.46 72.96
78 INT143370 Gene_expression of Mrgprd 10 0.72 6.91 8.87 72.72
79 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 72.56
80 INT193376 Gene_expression of WASF1 7 0.75 1.6 0.2 72.20
81 INT3439 Localization of Abat 1017 0.78 112.39 727.06 72.04
82 INT163052 Regulation of Msn 11 0.38 1.21 6.31 71.84
83 INT969 Negative_regulation of FASTK 5 0.38 4.03 1.14 70.96
84 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 70.88
85 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54 70.88
86 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24 70.88
87 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 70.72
88 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13 70.44
89 INT59139 Negative_regulation of Ctnnbl1 6 0.38 0.28 1.19 69.56
90 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 69.08
91 INT72294 Binding of CA3 3 0.32 0.54 0.55 69.00
92 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 68.96
93 INT69974 Positive_regulation of Oxtr 30 0.70 2.44 5.73 68.76
94 INT50535 Gene_expression of CA3 25 0.51 9.25 2.89 67.40
95 INT52132 Positive_regulation of Negative_regulation of Abat 9 0.50 0.53 7.03 67.24
96 INT72749 Regulation of Pth 4 0.62 1.39 1.14 67.04
97 INT1352 Localization of Acot1 728 0.80 73.01 296.01 67.00
98 INT287323 Positive_regulation of Localization of Dnah5 1 0.02 0 0.17 66.24
99 INT81210 Positive_regulation of PRKG1 71 0.70 26.83 19.89 66.16
100 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 65.40
101 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 65.40
102 INT123382 Gene_expression of Cxcr2 12 0.69 4.62 8.62 64.88
103 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86 64.12
104 INT59877 Regulation of Regulation of Prkcg 2 0.45 1.17 2.81 64.00
105 INT163054 Gene_expression of Msn 20 0.66 0.6 9.06 62.88
106 INT287320 Localization of Dnah5 1 0.04 0 0.14 62.16
107 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 61.28
108 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 60.76
109 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66 60.36
110 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 59.88
111 INT264027 Positive_regulation of Positive_regulation of Flvcr2 2 0.08 2.67 7.27 58.96
112 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 58.96
113 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 58.96
114 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65 58.96
115 INT248175 Positive_regulation of Cxcr2 1 0.35 0 0.27 58.96
116 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89 58.88
117 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 58.84
118 INT92017 Regulation of Gene_expression of Flvcr2 3 0.18 1.69 3.75 58.84
119 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44 57.16
120 INT117674 Regulation of Gene_expression of Nav1 16 0.62 11.5 22.01 56.88
121 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 56.20
122 INT111056 Negative_regulation of Gene_expression of Flvcr2 9 0.13 4.15 7.18 56.20
123 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 55.80
124 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14 55.80
125 INT32791 Gene_expression of Dpp6 5 0.76 2.51 4.04 55.60
126 INT103496 Gene_expression of Vps52 3 0.39 3.22 1.78 55.44
127 INT251446 Gene_expression of Dpp10 1 0.36 0.31 0.44 54.76
128 INT76845 Regulation of Gene_expression of Neurod1 2 0.44 0.28 0.44 53.60
129 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12 53.36
130 INT144524 Gene_expression of Mrgpra3 3 0.64 1.05 2.81 53.20
131 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 52.68
132 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77 52.64
133 INT49702 Negative_regulation of Negative_regulation of Grip2 9 0.43 1.77 3.54 52.60
134 INT164987 Gene_expression of Mrgprx1 5 0.64 4.26 3.47 52.48
135 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 52.24
136 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1 52.08
137 INT71629 Negative_regulation of Swd1 6 0.15 1.42 1.1 52.08
138 INT86488 Gene_expression of Kcnc1 34 0.66 3.58 4.72 52.04
139 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 52.00
140 INT59680 Binding of Lynx1 10 0.12 1.53 2.19 51.92
141 INT158 Localization of Prl 2431 0.81 378.96 952.2 50.40
142 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 49.84
143 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11 49.84
144 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54 49.56
145 INT2212 Binding of Abat 89 0.48 18.36 63.99 48.40
146 INT146339 Regulation of Cxcl1 6 0.43 3.76 3.65 46.08
147 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 45.00
148 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 44.32
149 INT293461 Binding of Kcnh1 1 0.48 0 0.03 41.92
150 INT247617 Positive_regulation of PAMR1 1 0.06 2.3 2.07 41.44
151 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 40.68
152 INT196192 Gene_expression of Mrgpre 21 0.77 14.87 6.53 40.64
153 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 37.84
154 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49 36.60
155 INT59489 Localization of Slc7a5 1 0.70 0 0.54 36.08
156 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59 35.28
157 INT5536 Regulation of NA 74 0.59 16.61 15.36 35.04
158 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33 34.92
159 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 34.60
160 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07 34.60
161 INT1540 Positive_regulation of SAFB 9 0.43 1.97 2.56 33.92
162 INT5743 Localization of NA 104 0.59 14.35 35.29 33.76
163 INT15027 Positive_regulation of Localization of NA 11 0.26 3.4 2.98 33.76
164 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 33.48
165 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 32.40
166 INT292922 Gene_expression of Olr717 1 0.01 0.12 0.19 32.40
167 INT38563 Negative_regulation of Gene_expression of Oxt 18 0.56 2.51 6.23 30.80
168 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69 28.32
169 INT230622 Negative_regulation of Gene_expression of MNX1 3 0.26 0.61 0.22 28.32
170 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26 28.16
171 INT7028 Localization of Pdyn 90 0.81 8.89 73.54 25.16
172 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28 25.00
173 INT27133 Gene_expression of Nfkbiz 5 0.60 0.74 1.5 25.00
174 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 24.64
175 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06 24.64
176 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 23.88
177 INT223628 Regulation of Gene_expression of Mrgpre 1 0.61 1.43 0.79 23.56
178 INT251443 Binding of Dpp10 1 0.19 0.18 0.03 23.36
179 INT193381 Gene_expression of PHLPP1 1 0.05 0.49 0.11 23.04
180 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 22.88
181 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 22.32
182 INT51259 Gene_expression of Zbtb38 17 0.05 5.63 9.51 21.60
183 INT135064 Gene_expression of Preb 2 0.38 0.18 0.54 20.72
184 INT230265 Binding of Cav3 2 0.42 0.74 0.44 19.52
185 INT241326 Gene_expression of Kcnn4 2 0.48 0.06 0.17 19.52
186 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 19.28
187 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 18.32
188 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 15.68
189 INT31125 Binding of Dpp6 10 0.36 0.22 8.26 15.08
190 INT251442 Binding of Kcnc1 3 0.22 0 0.08 15.08
191 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 15.04
192 INT150942 Regulation of Pik3c3 2 0.18 0.96 0.94 12.92
193 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 11.68
194 INT123419 Binding of NAV1 37 0.48 7.09 26.43 10.76
195 INT183057 Positive_regulation of Gene_expression of MNX1 2 0.38 0.75 0.1 9.52
196 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 8.28
197 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 7.44
198 INT211684 Regulation of Gene_expression of Cntnap1 1 0.04 0.54 2.38 7.36
199 INT211690 Gene_expression of Cntnap1 1 0.06 1.03 5.5 6.92
200 INT280864 Positive_regulation of Binding of Msn 1 0.35 0 0.15 5.20
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