P:rostroventromedial medulla

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Pain Term
Category Anatomy
Synonyms Rostral Ventromedial Medulla
Pain Specific No
Documents 42
Hot Single Events 46
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for rostroventromedial medulla. They are ordered first by their pain relevance and then by number of times they were reported for rostroventromedial medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 98.78
2 INT161412 Pag1 Positive_regulation of Gene_expression of Tens1 1 0.11 0.56 0.9 98.56
3 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 69.96
4 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 69.96
5 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 45.32
6 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23 5.00
7 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 5.00
8 INT285660 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
9 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
10 INT209593 Negative_regulation of Adcy1 Negative_regulation of Positive_regulation of Ltp 1 0.10 0 0.69 5.00
11 INT209591 Car2 Positive_regulation of Positive_regulation of Ltp 1 0.05 0 0.54 5.00
12 INT209592 Car2 Positive_regulation of Localization of Ltp 1 0.05 0 0.54 5.00
13 INT285661 Binding of Mgll and FAAH2 1 0.05 0.23 0.45 5.00
14 INT276511 Binding of Nts and Mir431 1 0.00 0 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for rostroventromedial medulla. They are ordered first by their pain relevance and then by number of times they were reported in rostroventromedial medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 100.00
2 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
3 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 100.00
4 INT19199 Negative_regulation of Rvm 16 0.37 10.07 21.73 100.00
5 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
6 INT10520 Regulation of Rvm 20 0.24 10.15 20.52 100.00
7 INT161734 Positive_regulation of Positive_regulation of Rvm 2 0.44 3.21 2.24 100.00
8 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
9 INT112338 Localization of Rvm 11 0.31 9.51 17.61 100.00
10 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37 100.00
11 INT71363 Binding of Rvm 9 0.31 3.23 10.83 100.00
12 INT13590 Negative_regulation of Localization of Nts 8 0.42 1.36 4.59 100.00
13 INT276500 Negative_regulation of Localization of Rvm 1 0.04 0.22 1.01 100.00
14 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.98
15 INT8363 Localization of Nts 135 0.81 14.29 61.71 99.96
16 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 99.84
17 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.68
18 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 99.68
19 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 99.68
20 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.68
21 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 99.66
22 INT98942 Gene_expression of Dtd1 1 0.52 0.36 0.3 99.54
23 INT62415 Binding of Htr7 6 0.47 1.76 2.26 99.36
24 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 99.30
25 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.08
26 INT9231 Binding of Htr3a 27 0.47 7.29 13.04 98.96
27 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 98.78
28 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 98.68
29 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 98.52
30 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 98.48
31 INT63628 Positive_regulation of Htr7 3 0.67 1.07 2.68 98.48
32 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81 98.32
33 INT140151 Gene_expression of Tens1 9 0.67 5.84 13.68 97.84
34 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 97.08
35 INT7327 Regulation of Th 164 0.62 29.67 110.14 96.80
36 INT1004 Regulation of Sst 140 0.62 18.52 94.84 96.80
37 INT11945 Regulation of Chat 38 0.62 7.75 14.97 96.80
38 INT18538 Regulation of Pnmt 11 0.60 1.03 3.84 96.80
39 INT24477 Regulation of Calb1 3 0.27 0.19 1.31 96.80
40 INT3948 Regulation of Cck 291 0.62 58.07 255.88 96.40
41 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 96.24
42 INT24958 Gene_expression of Nkx1-1 106 0.74 51.29 76.88 95.52
43 INT13593 Binding of Prss12 13 0.36 4.35 9.37 90.88
44 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 90.08
45 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83 82.52
46 INT287 Localization of Cck 518 0.81 86.84 364.04 82.00
47 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 78.72
48 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 75.68
49 INT1463 Binding of Pomc 129 0.48 15.89 56.27 73.88
50 INT1613 Binding of Nts 58 0.48 10.55 28.18 68.92
51 INT148901 Binding of Sort1 2 0.39 3.65 4.32 68.92
52 INT66881 Positive_regulation of Sort1 2 0.57 0.99 2.16 67.92
53 INT168396 Transcription of Cnr2 12 0.72 7.69 8.74 65.40
54 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 64.36
55 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 64.36
56 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 57.88
57 INT34398 Positive_regulation of Positive_regulation of Nts 13 0.49 1.13 5.28 54.16
58 INT276509 Positive_regulation of Positive_regulation of Sort1 1 0.41 0.22 0.76 53.44
59 INT187546 Gene_expression of Gtf2f2 2 0.58 1.13 0.95 53.08
60 INT10546 Positive_regulation of Prss12 12 0.44 4.57 10.05 48.56
61 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 43.92
62 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 43.64
63 INT521 Negative_regulation of Lrtomt 8 0.55 2.83 3.96 40.40
64 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 38.00
65 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
66 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 5.00
67 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
68 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
69 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
70 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
71 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
72 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
73 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 5.00
74 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 5.00
75 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
76 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
77 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 5.00
78 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 5.00
79 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 5.00
80 INT771 Regulation of Nts 93 0.61 13.13 53.57 5.00
81 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 5.00
82 INT122041 Binding of Ppara 308 0.48 189.17 51.48 5.00
83 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 5.00
84 INT63383 Binding of Cnr1 77 0.48 22.28 44.61 5.00
85 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78 5.00
86 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89 5.00
87 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 5.00
88 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
89 INT8362 Localization of Prss12 53 0.78 5.09 27 5.00
90 INT54467 Localization of Ltp 41 0.58 8.86 26.88 5.00
91 INT106720 Positive_regulation of Adcy1 30 0.50 22.05 22.68 5.00
92 INT153613 Gene_expression of Napepld 42 0.77 6.7 20.94 5.00
93 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 5.00
94 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 5.00
95 INT66004 Binding of Cnr2 35 0.48 12.82 18.63 5.00
96 INT8391 Positive_regulation of Gene_expression of Nts 23 0.67 5.05 14.59 5.00
97 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 5.00
98 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
99 INT130424 Negative_regulation of Adcy1 19 0.58 16.31 13.6 5.00
100 INT122037 Regulation of Ppara 93 0.62 56.28 12.89 5.00
101 INT107524 Gene_expression of Faah 17 0.78 7.93 11.91 5.00
102 INT116347 Positive_regulation of Positive_regulation of GRIN1 12 0.49 3.63 11.44 5.00
103 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9 5.00
104 INT29967 Positive_regulation of Positive_regulation of Car2 40 0.40 8.03 10.13 5.00
105 INT55038 Gene_expression of Adcy8 10 0.77 28.79 9.8 5.00
106 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41 5.00
107 INT8360 Positive_regulation of Localization of Prss12 14 0.26 1.72 9.38 5.00
108 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73 5.00
109 INT61264 Regulation of Jun 36 0.61 18.42 8.71 5.00
110 INT106719 Gene_expression of Adcy1 18 0.77 12.18 8.42 5.00
111 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 5.00
112 INT134864 Binding of Calm3 20 0.27 1.86 6.86 5.00
113 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6 5.00
114 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
115 INT134585 Negative_regulation of Cnr2 10 0.43 3.98 6.16 5.00
116 INT132682 Phosphorylation of Pag1 7 0.71 5.61 5.75 5.00
117 INT10547 Regulation of Prss12 11 0.41 3.11 5.74 5.00
118 INT65262 Gene_expression of Lox 47 0.74 36.59 5.65 5.00
119 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 5.00
120 INT130478 Localization of Grin2b 11 0.75 2.49 5.28 5.00
121 INT208108 Localization of Grin2a 19 0.70 1.5 5.22 5.00
122 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 5.00
123 INT106721 Regulation of Adcy1 6 0.45 2.32 4.17 5.00
124 INT148899 Regulation of Sort1 2 0.50 2.72 3.46 5.00
125 INT92151 Regulation of Faah 5 0.62 6.31 3.06 5.00
126 INT153616 Gene_expression of Mgll 5 0.50 2.72 3.03 5.00
127 INT150870 Regulation of Gene_expression of Faah 3 0.45 2.65 2.87 5.00
128 INT55036 Regulation of Adcy8 3 0.44 0.85 2.56 5.00
129 INT209594 Positive_regulation of Positive_regulation of GRIN3B 4 0.05 1.06 2.17 5.00
130 INT15243 Regulation of Egr1 19 0.61 7.6 2.13 5.00
131 INT278487 Positive_regulation of Gene_expression of Napepld 4 0.50 1.72 1.94 5.00
132 INT48787 Regulation of GRIA1 5 0.27 1.28 1.88 5.00
133 INT285646 Gene_expression of Naaa 4 0.28 1.01 1.84 5.00
134 INT209596 Gene_expression of GRIK1 2 0.65 0.35 1.69 5.00
135 INT189838 Regulation of Positive_regulation of Cnr2 1 0.41 1.19 1.51 5.00
136 INT221801 Localization of Lox 2 0.24 0.99 1.28 5.00
137 INT276507 Negative_regulation of Mir431 1 0.01 0.79 1.24 5.00
138 INT209595 Regulation of Positive_regulation of GRIN3B 1 0.01 0.37 1.18 5.00
139 INT58606 Negative_regulation of Binding of Prss12 4 0.20 0 1.01 5.00
140 INT209589 Positive_regulation of Grik4 1 0.01 0.34 0.85 5.00
141 INT285644 Binding of Gpr55 2 0.20 0.12 0.7 5.00
142 INT239014 Gene_expression of Ptpn22 2 0.37 1.58 0.52 5.00
143 INT189427 Gene_expression of FAAH2 3 0.16 0.23 0.42 5.00
144 INT285642 Negative_regulation of Napepld 3 0.21 0.78 0.25 5.00
145 INT285643 Positive_regulation of Napepld 1 0.15 0.35 0 5.00
146 INT276510 Gene_expression of Mir431 1 0.01 0 0 5.00
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