P:syringomyelia

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pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific No
Documents 434
Hot Single Events 14
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for syringomyelia. They are ordered first by their pain relevance and then by number of times they were reported for syringomyelia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT147232 Binding of tn and Cpe 1 0.03 1.55 0.95 95.16
2 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 66.80
3 INT239572 DPF1 Positive_regulation of AIS 1 0.02 0.71 0.24 63.32
4 INT36306 HADH Positive_regulation of NKG7 1 0.07 1.07 0.28 59.60
5 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26 26.64
6 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
7 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
8 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
9 INT239573 Binding of DPF1 and AIS 1 0.02 0.74 0.31 5.00
10 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 5.00
11 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
12 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
13 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
14 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
15 INT239571 Binding of PDGFC and IGSF10 1 0.00 0.34 0.08 5.00
16 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
17 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
18 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
19 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for syringomyelia. They are ordered first by their pain relevance and then by number of times they were reported in syringomyelia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT13607 Binding of Ack 11 0.36 5.77 6.01 100.00
2 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 100.00
3 INT76057 Regulation of sar 9 0.23 2.05 0.96 99.80
4 INT64824 Negative_regulation of sar 11 0.42 18.7 5.6 99.60
5 INT155002 Binding of SHFM1 2 0.26 1.07 0.22 99.52
6 INT100746 Localization of sar 2 0.62 13.88 2.61 99.40
7 INT9749 Positive_regulation of sar 25 0.50 9.96 2.09 98.86
8 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 98.04
9 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 97.84
10 INT17938 Binding of Cpe 28 0.48 11.17 13.62 95.16
11 INT131044 Binding of tn 2 0.30 2.58 1.93 95.16
12 INT111008 Transcription of ITPA 1 0.67 0.55 0.39 89.40
13 INT37649 Gene_expression of Fbp1 4 0.49 3.16 1.84 88.96
14 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 88.08
15 INT38564 Binding of AIS 36 0.38 27.77 9.31 79.76
16 INT81328 Gene_expression of sar 7 0.66 2.86 1.85 78.16
17 INT189130 Regulation of AIS 11 0.39 7.64 0.99 76.40
18 INT239575 Regulation of PDGFC 1 0.07 4.93 1.3 75.84
19 INT331605 Negative_regulation of Localization of sar 1 0.35 0.88 0.13 75.68
20 INT193576 Positive_regulation of Gene_expression of AIS 4 0.39 1.94 0.46 75.24
21 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 75.00
22 INT48944 Binding of Pts 8 0.41 3.23 1.03 75.00
23 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 74.36
24 INT171057 Gene_expression of PDGFC 7 0.15 5.84 1.22 71.36
25 INT69904 Binding of Hc 11 0.35 7.79 3.69 69.04
26 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 66.80
27 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 66.80
28 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 65.80
29 INT3521 Regulation of Csf2 38 0.54 11.09 12.73 64.00
30 INT239574 Binding of PDGFC 1 0.04 3.29 0.79 59.32
31 INT72126 Positive_regulation of HIST2H2AA3 16 0.38 3.94 2.89 50.00
32 INT17807 Positive_regulation of PDGFC 4 0.06 3.28 0.86 49.48
33 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 44.64
34 INT239579 Negative_regulation of GLC2A 1 0.02 0.85 0.15 42.32
35 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 36.88
36 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 35.64
37 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 35.64
38 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 34.16
39 INT239582 Gene_expression of LHX2 1 0.03 0.39 0 14.32
40 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 8.32
41 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
42 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
43 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 5.00
44 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
45 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
46 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
47 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
48 INT5008 Localization of Calca 204 0.81 80.35 125.16 5.00
49 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
50 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
51 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
52 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
53 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
54 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 5.00
55 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
56 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 5.00
57 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
58 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
59 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 5.00
60 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 5.00
61 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 5.00
62 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 5.00
63 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 5.00
64 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
65 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 5.00
66 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 5.00
67 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
68 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
69 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
70 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 5.00
71 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2 5.00
72 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
73 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 5.00
74 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
75 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84 5.00
76 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 5.00
77 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 5.00
78 INT66004 Binding of Cnr2 35 0.48 12.82 18.63 5.00
79 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
80 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 5.00
81 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
82 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 5.00
83 INT127022 Gene_expression of Lts1 43 0.23 28.29 12.64 5.00
84 INT50933 Transcription of Il6 38 0.72 24.31 11.58 5.00
85 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74 5.00
86 INT72579 Localization of BDNF 56 0.80 14.84 10.65 5.00
87 INT85048 Regulation of NGF 19 0.62 11.61 10.5 5.00
88 INT50196 Transcription of Il1b 25 0.69 19.08 10.43 5.00
89 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 5.00
90 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86 5.00
91 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57 5.00
92 INT77795 Localization of Gdnf 26 0.81 6.29 8.55 5.00
93 INT168399 Localization of Cnr2 12 0.81 4.37 6.77 5.00
94 INT134585 Negative_regulation of Cnr2 10 0.43 3.98 6.16 5.00
95 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 5.00
96 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65 5.00
97 INT91338 Binding of Lep 31 0.48 26.86 5.39 5.00
98 INT147584 Localization of AIS 38 0.63 12.83 5.27 5.00
99 INT58079 Localization of Tenc1 13 0.68 5.9 4.75 5.00
100 INT189842 Negative_regulation of Gene_expression of Cnr2 8 0.59 4.21 4.67 5.00
101 INT229788 Negative_regulation of SPTLC1 1 0.38 4.82 3.53 5.00
102 INT102516 Gene_expression of Map2 29 0.69 6.73 3.41 5.00
103 INT11107 Binding of Lbp 12 0.42 4.42 3.41 5.00
104 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 5.00
105 INT203154 Positive_regulation of Gene_expression of Lts1 6 0.17 3.68 2.67 5.00
106 INT96199 Negative_regulation of PGP 15 0.59 1.07 2.35 5.00
107 INT228442 Localization of Cntf 8 0.63 4.2 2.12 5.00
108 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09 5.00
109 INT72870 Negative_regulation of SPTLC2 7 0.57 1.82 1.73 5.00
110 INT19747 Regulation of Egf 14 0.46 4.67 1.68 5.00
111 INT96200 Gene_expression of PGP 9 0.76 0.79 1.63 5.00
112 INT211853 Phosphorylation of Tenc1 2 0.61 2.53 1.59 5.00
113 INT302990 Protein_catabolism of MBP 5 0.88 3.75 1.42 5.00
114 INT4928 Binding of Mag 9 0.26 7.62 1.42 5.00
115 INT351303 Regulation of Binding of Cnr2 1 0.10 0.66 1.39 5.00
116 INT351302 Regulation of Regulation of Cnr1 1 0.10 0.78 1.39 5.00
117 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31 5.00
118 INT110838 Regulation of AGXT 5 0.46 2.21 1.28 5.00
119 INT229791 Gene_expression of RAB7A 2 0.73 6.48 1.21 5.00
120 INT86670 Negative_regulation of AGXT 6 0.57 2.24 1.18 5.00
121 INT229792 Negative_regulation of Positive_regulation of RAB7A 1 0.40 1.49 1.17 5.00
122 INT229793 Negative_regulation of Positive_regulation of SPTLC1 1 0.43 1.49 1.17 5.00
123 INT66043 Regulation of SPTLC2 3 0.44 1.62 1.09 5.00
124 INT229787 Gene_expression of AGXT 4 0.16 0.94 1.08 5.00
125 INT229789 Regulation of RAB7A 4 0.42 7.09 0.72 5.00
126 INT229786 Transcription of SPTLC1 1 0.60 0.78 0.71 5.00
127 INT73815 Localization of Fgf1 10 0.80 1.73 0.69 5.00
128 INT66042 Positive_regulation of SPTLC2 2 0.68 0.97 0.66 5.00
129 INT355015 Protein_catabolism of Mbp 1 0.21 2.47 0.61 5.00
130 INT239577 Gene_expression of GLIPR1 1 0.03 2.34 0.5 5.00
131 INT241549 Negative_regulation of Gene_expression of AIS 5 0.37 3.72 0.48 5.00
132 INT196697 Binding of Srr 13 0.22 8.01 0.45 5.00
133 INT132516 Gene_expression of NEURL 8 0.35 5.96 0.44 5.00
134 INT144683 Regulation of Rtn4r 3 0.26 0.88 0.36 5.00
135 INT110837 Binding of SPTLC2 1 0.36 0.7 0.35 5.00
136 INT83237 Negative_regulation of SHFM1 2 0.42 0.66 0.26 5.00
137 INT292918 Binding of Jsr 4 0.17 1.19 0.24 5.00
138 INT229790 Regulation of Gene_expression of AGXT 1 0.11 0.47 0.24 5.00
139 INT239580 Regulation of GLIPR1 1 0.01 0.61 0.15 5.00
140 INT355012 Negative_regulation of Binding of Mag 1 0.09 0.38 0.11 5.00
141 INT355016 Phosphorylation of Rtn4r 1 0.11 0.37 0.11 5.00
142 INT355014 Positive_regulation of Phosphorylation of Rtn4r 1 0.08 0.37 0.11 5.00
143 INT239581 Positive_regulation of MYH16 1 0.46 0.25 0.1 5.00
144 INT217951 Gene_expression of MYH16 3 0.62 0.25 0.1 5.00
145 INT84653 Gene_expression of DPF1 2 0.30 1.3 0.1 5.00
146 INT239578 Positive_regulation of Gene_expression of CD52 2 0.16 1.37 0.03 5.00
147 INT239576 Regulation of Localization of AIS 1 0.35 0.65 0.03 5.00
148 INT212303 Positive_regulation of FANCE 1 0.04 0.06 0.03 5.00
149 INT212304 Regulation of Positive_regulation of FANCE 1 0.04 0.06 0.03 5.00
150 INT292917 Positive_regulation of Jsr 1 0.01 0.36 0 5.00
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