P:tail-flick

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pChart

Pain Term
Category Other
Synonyms Analgesimetric Procedure, Tail Flick
Pain Specific No
Documents 3872
Hot Single Events 200
Hot Interactions 94

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for tail-flick. They are ordered first by their pain relevance and then by number of times they were reported for tail-flick. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT113714 Em Positive_regulation of tf 1 0.32 0 2.5 100.00
2 INT113715 Msh3 Positive_regulation of tf 1 0.11 0 2.47 100.00
3 INT35982 LH Negative_regulation of tf 1 0.03 0.18 0.77 100.00
4 INT6077 Cck Negative_regulation of Localization of Penk 1 0.06 0 0.99 100.00
5 INT128513 Pnoc Regulation of Adarb1 1 0.01 0.92 3.14 99.84
6 INT128512 Regulation of Pnoc Regulation of Adarb1 1 0.01 0.46 1.58 99.84
7 INT26222 Calca Positive_regulation of Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02 99.72
8 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02 99.72
9 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49 99.64
10 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46 99.42
11 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35 98.80
12 INT120323 Slc5a7 Negative_regulation of Flvcr2 1 0.02 0.43 1.1 98.32
13 INT120324 Hc3 Negative_regulation of Flvcr2 1 0.06 0.42 1.09 98.32
14 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29 97.88
15 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79 97.68
16 INT144062 Grm8 Regulation of Localization of Pag1 1 0.21 0.63 0.79 97.08
17 INT66488 Binding of Oprl1 and Cbm4 1 0.01 0 1.17 96.88
18 INT153215 Htr5b Positive_regulation of Pag1 1 0.01 0.57 1.22 96.72
19 INT13756 Binding of Oprd1 and Scn4a 1 0.02 0 1.32 95.92
20 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32 95.82
21 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69 95.24
22 INT22109 Positive_regulation of Pomc Positive_regulation of Penk 1 0.35 0 0.99 95.00
23 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19 94.08
24 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2 94.08
25 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97 93.92
26 INT44312 Binding of Trh and Pag1 1 0.05 0.36 0.41 93.84
27 INT88971 Binding of Sult4a1 and Atrn 1 0.02 0.54 1.03 93.52
28 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92 93.16
29 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41 92.56
30 INT77377 Binding of Cnr1 and Fbln5 1 0.02 0 0.48 92.52
31 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81 92.40
32 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82 91.84
33 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52 91.72
34 INT9169 Pomc Positive_regulation of Localization of Cck 1 0.29 0 0.5 91.68
35 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 91.40
36 INT158809 Pag1 Regulation of Rvm 1 0.02 1.28 2.33 91.12
37 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55 91.04
38 INT43321 Oprd1 Regulation of Ap2m1 1 0.20 0 0.63 91.00
39 INT13349 Binding of Gabrg1 and Mastl 1 0.08 0.24 0.54 90.72
40 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55 90.64
41 INT90045 Oprd1 Positive_regulation of P9Ehs1 1 0.19 0.92 0.64 90.48
42 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14 89.84
43 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31 89.64
44 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44 89.60
45 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 89.56
46 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 89.56
47 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49 89.52
48 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49 89.52
49 INT150995 Sfpq Positive_regulation of Gene_expression of Il4 1 0.06 0.71 0.74 89.52
50 INT150997 Sfpq Positive_regulation of Gene_expression of Il10 1 0.09 0.71 0.74 89.52
51 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72 89.52
52 INT150993 Sfpq Positive_regulation of Gene_expression of Il1b 1 0.04 0.7 0.72 89.52
53 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72 89.52
54 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69 89.52
55 INT150994 Sfpq Negative_regulation of Gene_expression of Il1b 1 0.03 0.69 0.66 89.52
56 INT31861 Cd79b Regulation of Sst 1 0.49 0.31 0.56 88.72
57 INT31862 Pdyn Regulation of Sst 1 0.45 0.31 0.56 88.72
58 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28 88.56
59 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63 88.40
60 INT42001 Cck Regulation of Vip 1 0.28 0 1.51 87.88
61 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72 87.36
62 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28 86.56
63 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39 85.80
64 INT308892 Adp Positive_regulation of P2ry1 1 0.11 0.44 0.47 85.68
65 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54 85.60
66 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26 85.56
67 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26 85.56
68 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61 84.80
69 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8 84.68
70 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43 84.60
71 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35 84.32
72 INT31243 Binding of Mme and Cpe 1 0.01 0 0.72 83.20
73 INT30146 Binding of Adarb1 and Pdyn 1 0.01 0.17 1.91 82.56
74 INT119918 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 1.64 82.48
75 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67 82.48
76 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96 81.92
77 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21 81.88
78 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96 81.84
79 INT218844 Cysltr1 Regulation of Car1 1 0.01 1.42 0.55 81.76
80 INT218839 Ppp1r9a Regulation of Car1 1 0.12 1.42 0.55 81.76
81 INT218841 Ltp Regulation of Car1 1 0.15 1.42 0.55 81.76
82 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25 81.68
83 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11 81.52
84 INT77376 Tmie Negative_regulation of Mastl 1 0.01 0 0.59 81.24
85 INT77379 Tmie Negative_regulation of Ebp 1 0.03 0 0.59 81.24
86 INT77380 Tmie Negative_regulation of Fbln5 1 0.01 0 0.59 81.24
87 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73 80.72
88 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33 80.68
89 INT54199 Binding of Pag1 and Agp2 1 0.04 0.18 0.91 80.40
90 INT54198 Agp2 Negative_regulation of Pag1 1 0.05 0.18 0.91 80.40
91 INT54188 Agp2 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.91 80.40
92 INT54196 Binding of Oprd1 and Agp2 1 0.00 0.18 0.91 80.40
93 INT54202 Gnai1 Negative_regulation of Binding of Pag1 and Agp2 1 0.01 0.18 0.91 80.40
94 INT44143 Negative_regulation of Thop1 Negative_regulation of Protein_catabolism of Penk 1 0.46 0 0.99 80.20
95 INT59482 Cpe Positive_regulation of Rbm39 1 0.02 0 0.89 79.84
96 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 79.76
97 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11 79.12
98 INT51705 Binding of Penk and Naga 1 0.19 0.08 0.69 78.80
99 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9 78.64
100 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9 78.64
101 INT54187 Gnai1 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.9 78.64
102 INT67733 Binding of Tac1 and SLAMF6 1 0.00 0.17 0.45 78.20
103 INT67734 SLAMF6 Negative_regulation of Binding of Tac1 and SLAMF6 1 0.00 0.17 0.45 78.20
104 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66 78.00
105 INT43453 Pomc Negative_regulation of Localization of Avp 1 0.38 0.82 0.45 77.76
106 INT54194 Binding of Oprd1 and Pag1 1 0.01 0.18 0.89 77.16
107 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 77.04
108 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 76.52
109 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98 76.32
110 INT64480 Binding of OPRL1 and PNOC 2 0.33 0.23 4.38 75.20
111 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11 75.00
112 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1 75.00
113 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44 74.88
114 INT147890 Prok2 Positive_regulation of Localization of Abat 1 0.18 0.36 0.6 74.60
115 INT147891 Prokr1 Positive_regulation of Localization of Abat 1 0.05 0.36 0.6 74.60
116 INT125301 Nts Positive_regulation of Unc5c 1 0.00 0 1.03 74.56
117 INT56205 Binding of Ap1m2 and Insrr 1 0.00 0.07 0.96 74.48
118 INT149741 Rf Negative_regulation of Qrfp 1 0.00 0.26 1.06 74.40
119 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63 74.00
120 INT128515 Binding of PNOC and Pnoc 1 0.12 0.38 1.14 73.84
121 INT130607 Hcrt Positive_regulation of H1 1 0.59 0.39 1.02 73.80
122 INT121000 Binding of PAG1 and Nrm 1 0.13 0.67 1.25 73.60
123 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12 73.08
124 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 72.92
125 INT243772 Safb Negative_regulation of Gria1 1 0.23 0.84 0.17 72.48
126 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 0.01 0 1.58 71.88
127 INT51568 Acyp2-ps1 Positive_regulation of Positive_regulation of Fos 1 0.35 0.19 0.56 71.72
128 INT21331 Binding of Adarb1 and Gm5195 1 0.00 0.26 1.08 71.68
129 INT21329 Binding of Man2a2 and Gm5195 1 0.00 0.26 1.06 71.68
130 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1 71.68
131 INT21330 Binding of Htr1f and Gm5195 1 0.00 0.26 0.99 71.68
132 INT125300 Nts Positive_regulation of Ntsr1 1 0.04 0 0.99 71.36
133 INT9572 Binding of Nts and Trpv3 1 0.02 0.07 0.21 71.36
134 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48 71.00
135 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41 70.88
136 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84 70.36
137 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67 70.16
138 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76 69.68
139 INT137958 Asprv1 Positive_regulation of Localization of Pdyn 1 0.21 0 1.43 68.88
140 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2 67.84
141 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63 67.80
142 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24 66.76
143 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23 66.76
144 INT70225 oh Regulation of Oprd1 1 0.20 0.13 1.8 66.16
145 INT102841 Pdcl Regulation of Oprd1 1 0.02 0.12 0.77 65.08
146 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2 64.04
147 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51 63.36
148 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91 63.20
149 INT6320 Binding of Rbm39 and Scq1 1 0.03 0 1.92 62.24
150 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94 61.92
151 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07 60.76
152 INT85760 Binding of Pnoc and Noc3l 1 0.01 0 0.21 59.68
153 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6 58.32
154 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24 57.68
155 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41 56.84
156 INT152628 Mvk Negative_regulation of Cysltr1 1 0.46 0 0.13 55.68
157 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35 55.56
158 INT71395 Ugt2a2 Regulation of Bcl2a1a 1 0.00 0.1 1.32 55.28
159 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41 51.64
160 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4 51.08
161 INT57956 LOC365260 Negative_regulation of Cck 1 0.11 0 1.3 50.96
162 INT104710 Em Positive_regulation of Rbm39 1 0.02 0.07 1.76 50.24
163 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76 50.24
164 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66 50.16
165 INT85485 Phax Regulation of Gene_expression of Cck 1 0.07 0.61 0.91 48.84
166 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03 48.40
167 INT66569 Pomc Positive_regulation of Atxn2l 1 0.03 0 1.36 47.24
168 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49 45.60
169 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71 44.20
170 INT345180 Binding of Lpar4 and Gpr87 1 0.06 0.69 0.59 42.36
171 INT345192 Binding of Gpr87 and Lpar5 1 0.07 0.69 0.59 42.36
172 INT30525 Acyp2-ps1 Regulation of Oprl1 1 0.04 0.15 0.33 40.52
173 INT317529 Binding of Hint1 and Rgs17 1 0.32 0.07 0.98 40.40
174 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33 39.96
175 INT30523 Pomc Regulation of Oprl1 1 0.06 0.15 0.33 39.76
176 INT317550 Binding of Hint1 and Rgs20 1 0.32 0.07 0.98 39.60
177 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38 38.56
178 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94 35.84
179 INT239079 D0H4S114 Positive_regulation of Gene_expression of Cpa1 1 0.11 0.3 0.32 35.44
180 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03 35.04
181 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59 34.48
182 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59 34.48
183 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51 29.40
184 INT153289 Binding of Lpar1 and Gpr87 2 0.29 1.19 0.67 26.72
185 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78 25.00
186 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78 25.00
187 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59 25.00
188 INT168926 Binding of Om and Imraq2 1 0.01 0.07 0.91 25.00
189 INT168927 Positive_regulation of Binding of Om and Imraq2 1 0.02 0.07 0.91 25.00
190 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85 18.96
191 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 18.96
192 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96 18.08
193 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 16.08
194 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 16.08
195 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46 13.72
196 INT172512 Mir343 Regulation of ECT 1 0.03 0.08 0.45 11.92
197 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
198 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18 5.00
199 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
200 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for tail-flick. They are ordered first by their pain relevance and then by number of times they were reported in tail-flick. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5033 Negative_regulation of tf 39 0.54 13.37 48.62 100.00
2 INT9705 Negative_regulation of Tal2 11 0.36 4.45 8.71 100.00
3 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
4 INT17584 Regulation of tf 12 0.50 4.69 10.39 100.00
5 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
6 INT23224 Gene_expression of tf 99 0.56 60.22 22.03 100.00
7 INT9704 Negative_regulation of Negative_regulation of tf 8 0.49 1.75 15.4 100.00
8 INT9706 Gene_expression of Tal2 11 0.18 3.22 6.47 100.00
9 INT23226 Positive_regulation of tf 23 0.43 15.55 14.37 100.00
10 INT16110 Positive_regulation of ZC3H12D 30 0.46 6.27 18.72 100.00
11 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
12 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
13 INT13083 Regulation of Tal2 7 0.23 1.73 4.71 100.00
14 INT7320 Positive_regulation of Tal2 9 0.58 2.05 4.94 100.00
15 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
16 INT23225 Negative_regulation of Gene_expression of tf 7 0.34 3.66 4.87 100.00
17 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
18 INT18664 Regulation of Cspg5 1 0.45 0.11 1.1 100.00
19 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
20 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
21 INT6073 Negative_regulation of Localization of Penk 63 0.59 8.67 53.95 100.00
22 INT9703 Regulation of Negative_regulation of tf 2 0.41 1.16 2.1 100.00
23 INT18760 Negative_regulation of Positive_regulation of Cspg5 3 0.41 0.12 1.57 100.00
24 INT12913 Positive_regulation of LOC680436 5 0.58 0.47 3.09 100.00
25 INT10670 Negative_regulation of Gene_expression of Tal2 2 0.01 1.49 1.3 100.00
26 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68 100.00
27 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
28 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 100.00
29 INT68797 Negative_regulation of Em 5 0.55 0 2.96 100.00
30 INT3387 Negative_regulation of Gene_expression of LH 23 0.43 3.14 12.37 100.00
31 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77 100.00
32 INT44730 Gene_expression of Hc3 3 0.64 1.66 2.75 100.00
33 INT18656 Binding of Tal2 2 0.30 0 2.45 100.00
34 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68 100.00
35 INT112597 Positive_regulation of Msh3 2 0.25 0 1.42 100.00
36 INT44724 Negative_regulation of tk 5 0.26 2.54 1.3 100.00
37 INT16785 Negative_regulation of LOC680436 2 0.36 0.2 0.98 100.00
38 INT13294 Negative_regulation of Regulation of Pomc 5 0.38 2.83 2.01 100.00
39 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3 100.00
40 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
41 INT76426 Positive_regulation of Negative_regulation of Cpox 18 0.35 6.84 9.95 100.00
42 INT33374 Regulation of Htr5b 3 0.22 0.74 1.69 100.00
43 INT54577 Gene_expression of ZC3H12D 4 0.58 1.72 3.9 100.00
44 INT6246 Negative_regulation of Negative_regulation of Pomc 3 0.43 1.34 1.78 100.00
45 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61 100.00
46 INT34227 Positive_regulation of Negative_regulation of tf 1 0.04 0.27 0.75 100.00
47 INT35851 Negative_regulation of Positive_regulation of LOC680436 1 0.35 0.1 0.49 100.00
48 INT44731 Gene_expression of Slc5a7 4 0.76 0.83 1.58 100.00
49 INT35850 Negative_regulation of Gene_expression of LOC680436 1 0.36 0.08 0.48 100.00
50 INT7612 Positive_regulation of Positive_regulation of Cspg5 3 0.50 0.83 0.83 100.00
51 INT10627 Positive_regulation of Lnpep 24 0.69 3.36 7.85 100.00
52 INT103950 Positive_regulation of Negative_regulation of TF 1 0.14 0.17 0.63 100.00
53 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 100.00
54 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 100.00
55 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 100.00
56 INT9387 Positive_regulation of Cpe 27 0.70 3.99 8.87 100.00
57 INT39226 Positive_regulation of Negative_regulation of Cpe 2 0.45 0.17 0.93 100.00
58 INT33921 Positive_regulation of Catys1 1 0.01 0.54 0.49 100.00
59 INT33922 Gene_expression of Catys1 1 0.02 0.54 0.49 100.00
60 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.98
61 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.98
62 INT126812 Gene_expression of Cttn 9 0.57 0.81 1.23 99.86
63 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 99.84
64 INT83493 Negative_regulation of Htr5b 3 0.34 1.22 3.12 99.84
65 INT167 Regulation of Ebp 3 0.44 0.77 1.03 99.84
66 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22 99.84
67 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.80
68 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.80
69 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97 99.80
70 INT2165 Localization of Cga 41 0.80 4.02 19.53 99.80
71 INT13095 Positive_regulation of Localization of Cga 6 0.69 0.69 2.96 99.80
72 INT7611 Positive_regulation of Cspg5 17 0.67 2.97 12.2 99.78
73 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 99.78
74 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.76
75 INT68970 Positive_regulation of Pnoc 33 0.67 9.29 19.08 99.76
76 INT206593 Negative_regulation of Gene_expression of Comt 3 0.56 1.68 2.52 99.76
77 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93 99.76
78 INT230378 Negative_regulation of Gene_expression of Cnr2 5 0.43 1.08 2.1 99.76
79 INT292 Localization of Penk 876 0.81 88.44 669.14 99.72
80 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.72
81 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.72
82 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.72
83 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94 99.72
84 INT3770 Negative_regulation of Nrm 13 0.43 3.55 12.83 99.68
85 INT20408 Regulation of Negative_regulation of Pomc 3 0.45 0.38 3.51 99.68
86 INT153818 Negative_regulation of Gene_expression of GTS 3 0.16 0.3 4.14 99.68
87 INT37831 Negative_regulation of Negative_regulation of Nrm 1 0.43 0.23 1.2 99.68
88 INT1139 Gene_expression of IgG-2a 35 0.65 19.19 12 99.68
89 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 99.66
90 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 99.64
91 INT1728 Negative_regulation of Cndp2 36 0.57 3.76 25.39 99.64
92 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 99.64
93 INT3835 Positive_regulation of su 10 0.62 4.04 6.19 99.60
94 INT477 Localization of Avp 813 0.81 131.58 300.4 99.60
95 INT25242 Positive_regulation of Sigmar1 17 0.66 3.93 5.65 99.60
96 INT64192 Regulation of Gtf2a2 3 0.19 0.87 6.36 99.60
97 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 99.60
98 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 99.60
99 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.58
100 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 99.58
101 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 99.58
102 INT1295 Binding of Pomc 85 0.48 12.92 42.8 99.58
103 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 99.56
104 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 99.56
105 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2 99.56
106 INT54294 Localization of Spnb4 9 0.78 0 18.64 99.52
107 INT1396 Binding of Penk 355 0.48 22.79 269.65 99.52
108 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 99.50
109 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 99.50
110 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 99.48
111 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 99.48
112 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.48
113 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 99.48
114 INT22354 Positive_regulation of Lhb 13 0.63 2.15 3.74 99.48
115 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.48
116 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28 99.48
117 INT17197 Gene_expression of Cspg5 9 0.78 1.21 8.85 99.46
118 INT12914 Gene_expression of LOC680436 4 0.50 0.15 2.46 99.46
119 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44 99.46
120 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 99.44
121 INT45199 Protein_catabolism of Cndp2 7 0.86 0.31 3.15 99.44
122 INT2366 Binding of Cck 192 0.48 30.64 163.46 99.40
123 INT136934 Negative_regulation of Urb1 6 0.36 2.53 2.38 99.40
124 INT28893 Positive_regulation of Atp5o 3 0.43 0.27 2.9 99.40
125 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48 99.40
126 INT152970 Positive_regulation of Negative_regulation of Urb1 1 0.18 0.49 0.62 99.40
127 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 99.40
128 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 99.38
129 INT10520 Regulation of Rvm 20 0.24 10.15 20.52 99.38
130 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 99.38
131 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 99.38
132 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.36
133 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.36
134 INT10659 Regulation of Syt17 3 0.39 2.16 4.53 99.36
135 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 99.36
136 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 99.36
137 INT29893 Negative_regulation of Prkacb 4 0.37 1.14 5.04 99.36
138 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 99.36
139 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52 99.36
140 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 99.34
141 INT90072 Regulation of Regulation of Oprd1 1 0.41 0 0.9 99.34
142 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 99.32
143 INT164010 Gene_expression of CNBP 7 0.53 9.13 1.71 99.32
144 INT25381 Localization of Csf2 62 0.76 47.48 9.03 99.30
145 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 99.28
146 INT797 Regulation of Penk 812 0.62 111.13 542.24 99.28
147 INT12858 Negative_regulation of Localization of Insrr 2 0.18 0.26 0.92 99.24
148 INT6301 Positive_regulation of Trpc6 8 0.67 4.15 1.59 99.22
149 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.20
150 INT97665 Negative_regulation of Regulation of Pnoc 3 0.43 0.72 2.29 99.20
151 INT128511 Negative_regulation of Positive_regulation of Pnoc 2 0.42 0.45 2.26 99.20
152 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 99.18
153 INT1319 Gene_expression of Oprl1 65 0.78 9.34 42.41 99.16
154 INT21223 Positive_regulation of Gene_expression of Oprl1 10 0.70 2.21 9.24 99.16
155 INT51654 Regulation of Bad 21 0.40 12.18 4.06 99.16
156 INT30008 Binding of Hrh1 17 0.45 6.8 11.41 99.12
157 INT64326 Negative_regulation of Binding of Hrh1 4 0.15 1.41 3.65 99.12
158 INT112338 Localization of Rvm 11 0.31 9.51 17.61 99.12
159 INT2649 Regulation of Calca 433 0.62 146.05 330.95 99.12
160 INT161352 Gene_expression of Map3k12 3 0.24 0.59 6.16 99.12
161 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86 99.12
162 INT13484 Negative_regulation of Morph1 2 0.31 0 2.17 99.10
163 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 99.08
164 INT2158 Negative_regulation of Positive_regulation of LH 41 0.58 4.52 17.75 99.08
165 INT7553 Negative_regulation of Pih1d2 1 0.15 1.67 2.68 99.06
166 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 99.04
167 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 99.04
168 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 99.04
169 INT95617 Regulation of Msx1 2 0.56 1.05 0.73 99.04
170 INT5791 Positive_regulation of Positive_regulation of Rbm39 13 0.25 1.61 9.88 99.00
171 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 99.00
172 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74 99.00
173 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95 99.00
174 INT1158 Regulation of Agt 106 0.61 29.4 30.29 98.96
175 INT7827 Binding of Cck 32 0.48 4.66 23.73 98.96
176 INT26289 Positive_regulation of Map3k12 2 0.11 0 0.79 98.96
177 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54 98.92
178 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09 98.92
179 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 98.92
180 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 98.88
181 INT20459 Regulation of Ripk2 5 0.44 0 4.53 98.88
182 INT462 Regulation of Pomc 157 0.62 41.67 67.27 98.88
183 INT120873 Gene_expression of Fhl1 3 0.08 0.45 1.9 98.88
184 INT120322 Negative_regulation of Gene_expression of Hc3 1 0.34 0.43 1.16 98.88
185 INT28001 Gene_expression of Gpm6a 23 0.66 16.66 21.09 98.88
186 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52 98.88
187 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 98.86
188 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 98.84
189 INT54297 Regulation of Localization of Spnb4 3 0.44 0 4.36 98.84
190 INT2758 Binding of Dbp 36 0.44 8.3 14.47 98.84
191 INT109507 Regulation of Map3k12 2 0.54 0 1.43 98.84
192 INT287 Localization of Cck 518 0.81 86.84 364.04 98.82
193 INT134315 Gene_expression of RT1-Hb-ps1 3 0.35 3.35 1.34 98.82
194 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 98.80
195 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 98.80
196 INT12575 Regulation of Hpse 33 0.59 17.7 18.45 98.80
197 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 98.76
198 INT1116 Regulation of Ren 103 0.62 27.66 33.26 98.76
199 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82 98.74
200 INT114 Binding of Oprl1 139 0.48 23 103.35 98.74
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