P:tonic descending inhibition

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pChart

Pain Term
Category Process
Synonyms None
Pain Specific Yes
Documents 44
Hot Single Events 10
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for tonic descending inhibition. They are ordered first by their pain relevance and then by number of times they were reported for tonic descending inhibition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 87.64
2 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 25.00
3 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for tonic descending inhibition. They are ordered first by their pain relevance and then by number of times they were reported in tonic descending inhibition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT15158 Positive_regulation of Vegfc 6 0.68 1.07 6.52 98.96
2 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 97.88
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 94.32
4 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 89.24
5 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52 89.24
6 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97 86.36
7 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 80.40
8 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 80.24
9 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 80.24
10 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37 80.24
11 INT17199 Negative_regulation of Cspg5 7 0.56 3.07 11.26 71.20
12 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 69.48
13 INT14054 Positive_regulation of H2-Ab1 10 0.69 2.98 6.25 53.32
14 INT22984 Positive_regulation of FRTS 12 0.67 5.24 2.25 47.76
15 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 25.00
16 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 25.00
17 INT66779 Binding of Pnoc 79 0.48 6.43 60.46 25.00
18 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 25.00
19 INT9705 Negative_regulation of Tal2 11 0.36 4.45 8.71 25.00
20 INT12787 Positive_regulation of Mott1 6 0.05 1.95 1.55 25.00
21 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 5.00
22 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 5.00
23 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
24 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
25 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 5.00
26 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 5.00
27 INT4822 Localization of Ca2 417 0.80 99.57 96.45 5.00
28 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 5.00
29 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
30 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
31 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 5.00
32 INT5048 Binding of Edn1 55 0.47 18.86 19.16 5.00
33 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72 5.00
34 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 5.00
35 INT19799 Binding of Ca2 71 0.48 13.69 12.92 5.00
36 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 5.00
37 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 5.00
38 INT49205 Positive_regulation of B3GAT1 20 0.67 10.28 8.71 5.00
39 INT114171 Phosphorylation of Grip2 11 0.49 5.75 8.31 5.00
40 INT31761 Positive_regulation of Itpr3 32 0.58 5.95 8.22 5.00
41 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 5.00
42 INT218698 Negative_regulation of Positive_regulation of Fig4 11 0.20 6.01 6.32 5.00
43 INT107771 Localization of HSPG2 10 0.78 8.47 4.3 5.00
44 INT48786 Phosphorylation of GRIA1 7 0.80 1.89 3.91 5.00
45 INT67474 Negative_regulation of B3GAT1 9 0.57 5.43 3.73 5.00
46 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56 5.00
47 INT125998 Binding of Camk2a 3 0.36 0.89 2.67 5.00
48 INT81242 Positive_regulation of Cacna1i 2 0.07 0.35 0.84 5.00
49 INT235561 Localization of GRIA1 2 0.06 0.37 0.68 5.00
50 INT235562 Positive_regulation of Localization of GRIA1 1 0.01 0.37 0.46 5.00
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