P:transcutaneous nerve stimulation

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Pain Term
Category Treatment
Synonyms Transcutaneous Electrical Nerve Stimulation
Pain Specific Yes
Documents 1127
Hot Single Events 107
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for transcutaneous nerve stimulation. They are ordered first by their pain relevance and then by number of times they were reported for transcutaneous nerve stimulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT45502 TNS1 Positive_regulation of VIP 1 0.47 0.52 1.5 100.00
2 INT117082 TNS3 Regulation of Ssr1 1 0.05 0 1.16 100.00
3 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2 100.00
4 INT40209 TNS3 Regulation of POMC 1 0.16 0.27 1.47 100.00
5 INT160399 Tns3 Regulation of Casr 1 0.30 0.1 0.22 99.78
6 INT160402 Tns3 Regulation of Positive_regulation of Casr 1 0.30 0.1 0.22 99.78
7 INT164665 Adarb1 Positive_regulation of Negative_regulation of Tens1 1 0.03 0.42 1.97 99.20
8 INT168445 Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn 1 0.14 0.66 0.46 96.56
9 INT65663 Tns1 Regulation of Vip 1 0.11 0.2 0.25 75.00
10 INT161412 Pag1 Positive_regulation of Gene_expression of Tens1 1 0.11 0.56 0.9 75.00
11 INT160400 Binding of Tns3 and Positive_regulation of Casr 1 0.38 0 0 50.00
12 INT160401 Tns3 Positive_regulation of Casr 1 0.38 0 0 50.00
13 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
14 INT332806 Positive_regulation of Ccl20 Regulation of Map3k8 1 0.05 0.05 0.1 5.00
15 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 5.00
16 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 5.00
17 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03 5.00
18 INT270780 BPs Positive_regulation of DMD 1 0.02 0 0 5.00
19 INT270778 Binding of TNFSF11 and CALCRL 1 0.00 0.44 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for transcutaneous nerve stimulation. They are ordered first by their pain relevance and then by number of times they were reported in transcutaneous nerve stimulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140151 Gene_expression of Tens1 9 0.67 5.84 13.68 100.00
2 INT163365 Positive_regulation of TNS3 2 0.41 0.96 4.18 100.00
3 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
4 INT109037 Regulation of Tens1 4 0.33 1.93 7.07 100.00
5 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
6 INT204557 Positive_regulation of Tens1 1 0.36 2.69 3.04 100.00
7 INT45050 Gene_expression of Tns1 5 0.66 1.09 3.02 100.00
8 INT60725 Negative_regulation of Tens1 4 0.42 2.49 4.87 100.00
9 INT38929 Positive_regulation of Tns1 5 0.43 1.11 3.24 100.00
10 INT150516 Regulation of Tns3 2 0.53 0.55 1.81 100.00
11 INT12370 Gene_expression of TNS1 6 0.67 1.7 1.37 100.00
12 INT164664 Localization of Tens1 1 0.61 0.37 2.67 100.00
13 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 100.00
14 INT150517 Positive_regulation of Tns3 1 0.44 0.06 0.72 100.00
15 INT210886 Localization of TNS3 2 0.62 1.26 2.1 100.00
16 INT275 Regulation of Tns1 2 0.28 0.47 1.37 100.00
17 INT109378 Regulation of Phosphorylation of Fos 3 0.26 1.61 2.45 100.00
18 INT3838 Regulation of FCGR3B 16 0.60 6.67 5.53 100.00
19 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
20 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 100.00
21 INT37179 Negative_regulation of TNS3 2 0.45 0.63 0.4 100.00
22 INT87064 Regulation of Regulation of FCGR3B 1 0.43 0.1 0.3 100.00
23 INT1975 Regulation of Regulation of Prl 32 0.59 5.78 18.53 100.00
24 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 100.00
25 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 100.00
26 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13 99.98
27 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 99.98
28 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 99.98
29 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 99.98
30 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 99.92
31 INT110077 Gene_expression of EMILIN1 3 0.58 0.6 0.38 99.92
32 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 99.90
33 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 99.88
34 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.88
35 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 99.86
36 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 99.86
37 INT287 Localization of Cck 518 0.81 86.84 364.04 99.84
38 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.78
39 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.74
40 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78 99.74
41 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92 99.72
42 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 99.72
43 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 99.70
44 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14 99.68
45 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64 99.58
46 INT2732 Gene_expression of VIP 74 0.78 24.57 33.72 99.56
47 INT127276 Gene_expression of Slurp1 12 0.59 4.99 5.73 99.44
48 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.40
49 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.36
50 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38 99.36
51 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44 99.36
52 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 99.36
53 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.32
54 INT5045 Regulation of VIP 26 0.62 7.15 11.61 99.32
55 INT31875 Regulation of CCBE1 8 0.04 4.18 2.64 99.32
56 INT43898 Regulation of Gene_expression of CCBE1 1 0.01 0.17 0.5 99.32
57 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91 99.20
58 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 99.20
59 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.18
60 INT610 Regulation of PENK 47 0.62 14.17 31.55 99.12
61 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 99.00
62 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 99.00
63 INT38014 Regulation of Casr 7 0.31 1.14 1.87 98.98
64 INT22949 Gene_expression of CCBE1 8 0.19 4.27 3.25 98.60
65 INT162 Regulation of Prl 794 0.62 165.01 322.24 98.58
66 INT9012 Localization of Vip 283 0.81 31.71 106.16 98.54
67 INT38249 Positive_regulation of VIPR1 9 0.40 2.58 3.96 98.52
68 INT169113 Negative_regulation of Phosphorylation of Fos 1 0.42 2.17 3.12 98.50
69 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05 98.44
70 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98 98.44
71 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1 98.44
72 INT121379 Positive_regulation of Casr 13 0.66 2.92 2.34 98.38
73 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 98.32
74 INT67274 Negative_regulation of Tes 2 0.38 0.09 0.82 97.44
75 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 97.28
76 INT168444 Positive_regulation of Positive_regulation of C2 2 0.43 0.93 0.85 96.56
77 INT74166 Positive_regulation of C2 10 0.55 2.83 1.05 96.56
78 INT443 Localization of POMC 1020 0.81 284.52 443.17 96.28
79 INT425 Localization of PRL 455 0.81 189.64 144.8 96.04
80 INT168443 Positive_regulation of Positive_regulation of Dcn 1 0.17 0.65 0.46 95.84
81 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13 95.76
82 INT249 Localization of GHRH 215 0.80 78.02 51.87 95.48
83 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74 95.48
84 INT3395 Negative_regulation of VIP 15 0.59 4.23 5.62 95.44
85 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 95.44
86 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 95.40
87 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 95.36
88 INT252 Localization of GH1 529 0.80 227.4 122.05 94.84
89 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 94.40
90 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 94.00
91 INT8725 Gene_expression of Mln 32 0.77 14.9 12.22 93.36
92 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 93.12
93 INT87837 Binding of Dcn 4 0.35 1.28 0.82 92.24
94 INT161574 Localization of CENPJ 7 0.73 6.11 1.54 91.40
95 INT164955 Positive_regulation of SDS 4 0.30 0.72 1.05 91.32
96 INT27303 Binding of FCGR3B 26 0.46 5.15 3.86 90.92
97 INT43899 Positive_regulation of Positive_regulation of VIP 4 0.57 1.71 1.42 90.60
98 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34 90.08
99 INT15161 Positive_regulation of Localization of VIP 12 0.50 3.3 7.87 89.56
100 INT7383 Localization of VIP 53 0.81 17.7 22.65 89.28
101 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 89.12
102 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36 88.88
103 INT30444 Negative_regulation of Protein_catabolism of POMC 4 0.51 2.11 4.53 88.88
104 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59 88.80
105 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 85.52
106 INT8824 Regulation of Vip 95 0.62 15.7 43.63 81.76
107 INT146182 Positive_regulation of CD96 3 0.49 2.56 2.81 81.28
108 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 79.08
109 INT93658 Transcription of Nos1 16 0.72 6.85 6.16 79.08
110 INT19689 Regulation of Tes 5 0.24 1.01 2.76 75.28
111 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 75.00
112 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 75.00
113 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 75.00
114 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 75.00
115 INT19203 Positive_regulation of Regulation of Vip 6 0.49 0.9 2.8 75.00
116 INT19202 Regulation of Positive_regulation of Vip 4 0.45 2.07 2.58 75.00
117 INT67096 Positive_regulation of CSDA 2 0.22 0.74 0.78 75.00
118 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 74.24
119 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 69.32
120 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 67.76
121 INT175904 Localization of RAC1 7 0.41 5.05 0.86 63.64
122 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86 57.48
123 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39 57.44
124 INT159262 Positive_regulation of EMILIN1 5 0.26 0.11 0.41 56.20
125 INT296899 Regulation of Gene_expression of CTNND2 1 0.44 1.13 0.49 55.28
126 INT159265 Regulation of EMILIN1 3 0.10 0.12 0.29 52.92
127 INT130343 Gene_expression of CTNND2 5 0.75 6.98 1.38 52.16
128 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 50.00
129 INT3840 Negative_regulation of FCGR3B 18 0.59 8.9 5.97 50.00
130 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09 50.00
131 INT73663 Negative_regulation of Gene_expression of FCGR3B 7 0.42 3.88 1 50.00
132 INT102794 Binding of Tns3 3 0.31 0.78 0.64 50.00
133 INT77562 Regulation of TNS3 5 0.39 1 0.55 50.00
134 INT160398 Gene_expression of Tns3 1 0.47 0 0 50.00
135 INT148408 Positive_regulation of HN1 1 0.30 0.17 0 50.00
136 INT1617 Positive_regulation of Binding of Oprl1 10 0.59 0.63 9.79 49.52
137 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 47.52
138 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38 44.24
139 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 43.12
140 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7 39.36
141 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 39.32
142 INT74688 Regulation of Nos1 55 0.62 22.16 25.3 39.04
143 INT256655 Positive_regulation of Psma1 1 0.20 0.8 1.45 33.24
144 INT9311 Regulation of Ssr1 13 0.60 6.41 6.58 32.24
145 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 25.00
146 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 25.00
147 INT69991 Negative_regulation of Gene_expression of Hmox2 3 0.04 2.05 2.51 25.00
148 INT76198 Positive_regulation of ADORA3 3 0.45 1.53 1.7 25.00
149 INT22022 Regulation of PPY 8 0.26 5.52 5.02 24.00
150 INT340382 Regulation of Regulation of PPY 1 0.12 0.94 0.94 24.00
151 INT153860 Positive_regulation of Ept1 2 0.14 0.27 0.7 15.28
152 INT197019 Negative_regulation of EMILIN1 1 0.10 0.3 0.2 11.32
153 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 5.00
154 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
155 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
156 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
157 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 5.00
158 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
159 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
160 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
161 INT1026 Binding of Lbp 207 0.48 150.96 119.16 5.00
162 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
163 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
164 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 5.00
165 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
166 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
167 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
168 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
169 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 5.00
170 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 5.00
171 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
172 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 5.00
173 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 5.00
174 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
175 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
176 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 5.00
177 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
178 INT52179 Regulation of Lbp 39 0.61 25.4 18.32 5.00
179 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
180 INT22068 Binding of CALCRL 53 0.41 6.14 17.32 5.00
181 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 5.00
182 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
183 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 5.00
184 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 5.00
185 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57 5.00
186 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 5.00
187 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19 5.00
188 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 5.00
189 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
190 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52 5.00
191 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 5.00
192 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 5.00
193 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 5.00
194 INT3180 Positive_regulation of PPY 39 0.63 25.57 10.15 5.00
195 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 5.00
196 INT1168 Binding of PROC 62 0.38 44.15 9.04 5.00
197 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 5.00
198 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
199 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 5.00
200 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 5.00
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