P:transdermal

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pChart

Pain Term
Category Treatment
Synonyms None
Pain Specific No
Documents 1885
Hot Single Events 200
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for transdermal. They are ordered first by their pain relevance and then by number of times they were reported for transdermal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT19879 Regulation of GNRH1 Regulation of Lhb 1 0.05 0 0.53 97.12
2 INT5132 GNRH1 Regulation of Lhb 2 0.08 0 0.52 97.12
3 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87 95.84
4 INT264569 Binding of STS and ATF7IP 1 0.03 0.15 0.25 95.40
5 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 94.36
6 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 93.72
7 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 78.56
8 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13 75.00
9 INT151409 Binding of Cp and Cd8b 1 0.16 0 0.84 75.00
10 INT166802 PEG10 Regulation of Gene_expression of LAMC2 1 0.08 0 0.12 75.00
11 INT327188 Gnat3 Regulation of PAEP 1 0.25 1.38 0.11 71.76
12 INT160445 Tpsab1 Positive_regulation of Gene_expression of SPG21 1 0.48 0.96 0.48 69.04
13 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48 69.04
14 INT352488 Binding of EPO and TNFRSF1A 1 0.14 0.18 0.12 64.08
15 INT327189 Gnat3 Regulation of Positive_regulation of PAEP 1 0.25 0.72 0.07 63.52
16 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33 50.00
17 INT112018 Binding of Hand1 and IgG2a 2 0.22 0.84 0.32 50.00
18 INT263495 Hand1 Regulation of Localization of Hand2 1 0.12 0.5 0.09 50.00
19 INT263496 Hand2 Regulation of Localization of Hand1 1 0.12 0.5 0.09 50.00
20 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06 50.00
21 INT263497 Hand1 Regulation of Binding of IFN1@ 1 0.28 0.16 0 50.00
22 INT302311 PTH Negative_regulation of Gene_expression of SOST 1 0.29 0.59 0 34.88
23 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
24 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
25 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
26 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
27 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78 5.00
28 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
29 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
30 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
31 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
32 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
33 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 5.00
34 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 5.00
35 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 5.00
36 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 5.00
37 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 5.00
38 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5 5.00
39 INT203150 Binding of Ighg2b and IgG2a 1 0.11 1.35 0.47 5.00
40 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
41 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
42 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38 5.00
43 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 5.00
44 INT203151 Binding of Rnase1 and Trav6-3 1 0.03 1.51 0.36 5.00
45 INT267644 Binding of Das and RLS 1 0.06 1.04 0.35 5.00
46 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 5.00
47 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 5.00
48 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
49 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 5.00
50 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 5.00
51 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 5.00
52 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26 5.00
53 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
54 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
55 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22 5.00
56 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 5.00
57 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
58 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18 5.00
59 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18 5.00
60 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18 5.00
61 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17 5.00
62 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
63 INT234113 COL18A1 Negative_regulation of Phosphorylation of VEGFA 1 0.26 0.17 0.16 5.00
64 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
65 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
66 INT234112 Binding of VEGFA and COL18A1 1 0.21 0.16 0.15 5.00
67 INT330467 IL12A Positive_regulation of Localization of TH1L 1 0.16 0.3 0.14 5.00
68 INT196436 Cdk4 Negative_regulation of Ccnd1 Positive_regulation of Ccnd1 1 0.04 1.18 0.13 5.00
69 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
70 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
71 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13 5.00
72 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
73 INT325056 Binding of E2f1 and Ang 1 0.06 1.3 0.12 5.00
74 INT325057 Binding of Hand1 and Ang 1 0.01 1.29 0.12 5.00
75 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 5.00
76 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
77 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
78 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
79 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
80 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
81 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
82 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1 5.00
83 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
84 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
85 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1 5.00
86 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
87 INT280451 IER5 Positive_regulation of Phc1 1 0.00 0.56 0.09 5.00
88 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 5.00
89 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
90 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08 5.00
91 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08 5.00
92 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08 5.00
93 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 5.00
94 INT325058 Igf1 Positive_regulation of Ang 1 0.04 1.4 0.08 5.00
95 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
96 INT271493 Ctbs Negative_regulation of Hand1 1 0.04 0.63 0.07 5.00
97 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
98 INT355879 Binding of Sry and Eae1 1 0.05 1.34 0.07 5.00
99 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
100 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07 5.00
101 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
102 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 5.00
103 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
104 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
105 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
106 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
107 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
108 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
109 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
110 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
111 INT325060 Binding of Insr and Hand1 1 0.00 0.16 0.05 5.00
112 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
113 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
114 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
115 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 5.00
116 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
117 INT196435 Lhb Positive_regulation of Mapk1 1 0.12 0.77 0.04 5.00
118 INT266445 Binding of HEY1 and GOPC 1 0.00 2.92 0.04 5.00
119 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 5.00
120 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 5.00
121 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
122 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 5.00
123 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.00
124 INT266452 Binding of Acot1 and GOPC 1 0.02 1.23 0.04 5.00
125 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 5.00
126 INT266454 Binding of HEY1 and Acot1 1 0.00 1.19 0.04 5.00
127 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
128 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 5.00
129 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
130 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
131 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03 5.00
132 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
133 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
134 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 5.00
135 INT350486 Cebpb Positive_regulation of IgG2a 1 0.00 0.42 0 5.00
136 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 5.00
137 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00
138 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
139 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 5.00
140 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0 5.00
141 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0 5.00
142 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0 5.00
143 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 5.00
144 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
145 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0 5.00
146 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
147 INT266453 SNRNP70 Regulation of Acot1 1 0.00 0.53 0 5.00
148 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0 5.00
149 INT196434 Binding of Ccne2 and Cdc25a 1 0.01 0.48 0 5.00
150 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0 5.00
151 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0 5.00
152 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 5.00
153 INT271982 Binding of Skp2 and Psmd9 1 0.01 0.68 0 5.00
154 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0 5.00
155 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0 5.00
156 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0 5.00
157 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0 5.00
158 INT272000 Binding of Skp2 and Hecw1 1 0.01 0.11 0 5.00
159 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0 5.00
160 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0 5.00
161 INT331909 Binding of ALB and SPARC 1 0.06 2.01 0 5.00
162 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 5.00
163 INT271979 Skp2 Positive_regulation of Protein_catabolism of Psmd9 1 0.01 0.35 0 5.00
164 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 5.00
165 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0 5.00
166 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0 5.00
167 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0 5.00
168 INT267136 Binding of CD44 and FN1 2 0.04 0.56 0 5.00
169 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0 5.00
170 INT211067 Pth Regulation of DMD 1 0.01 0.12 0 5.00
171 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0 5.00
172 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0 5.00
173 INT327198 DBT Positive_regulation of Gene_expression of ESRRA 1 0.00 0.42 0 5.00
174 INT350487 Cebpb Positive_regulation of Cebpb Positive_regulation of IgG2a 1 0.00 0.42 0 5.00
175 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0 5.00
176 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0 5.00
177 INT271984 Binding of Tsc2 and Skp2 1 0.06 0.34 0 5.00
178 INT272011 Binding of RAB5A and Tsc2 1 0.02 0.16 0 5.00
179 INT272004 Binding of Hspa1b and Tsc2 1 0.01 0.45 0 5.00
180 INT271983 Binding of Tsc2 and Rap1a 1 0.02 0.16 0 5.00
181 INT262716 Binding of ACHE and BCHE 1 0.09 0.11 0 5.00
182 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0 5.00
183 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 5.00
184 INT272005 Phosphorylation of Tsc1 Regulation of Binding of Cdk1 and Plk1 1 0.02 0.3 0 5.00
185 INT271989 Binding of Tsc2 and Psmd9 1 0.02 0.47 0 5.00
186 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0 5.00
187 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0 5.00
188 INT334920 GNRH1 Positive_regulation of Gene_expression of PLOD1 1 0.16 0.52 0 5.00
189 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0 5.00
190 INT271987 Tsc2 Regulation of Skp2 1 0.10 0.28 0 5.00
191 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0 5.00
192 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for transdermal. They are ordered first by their pain relevance and then by number of times they were reported in transdermal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT185520 Regulation of Binding of Vms1 2 0.09 0.86 0.57 100.00
2 INT26863 Regulation of Vms1 7 0.09 2.67 2.23 100.00
3 INT2893 Localization of Oxt 219 0.80 28.96 79.43 100.00
4 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65 100.00
5 INT146402 Regulation of Gnat3 6 0.31 1.52 0.44 100.00
6 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 100.00
7 INT82214 Transcription of PTH 6 0.54 3.33 1.11 100.00
8 INT2140 Regulation of REN 104 0.62 28.24 24.49 100.00
9 INT53451 Regulation of TAT 6 0.44 3.07 1.61 100.00
10 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 100.00
11 INT180588 Gene_expression of HEYL 13 0.52 8.37 1.19 99.98
12 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 99.92
13 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44 99.84
14 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.84
15 INT104168 Protein_catabolism of Nfasc 4 0.89 1.31 0.52 99.84
16 INT33854 Localization of OPA1 19 0.65 10.55 5.04 99.82
17 INT25136 Localization of Gnat3 23 0.75 5.01 3.65 99.82
18 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 99.82
19 INT114162 Localization of Srms 5 0.60 2.22 4.14 99.80
20 INT66002 Binding of LAMC2 9 0.47 4.5 2.54 99.80
21 INT19993 Negative_regulation of Ren1 43 0.58 20.89 5.04 99.78
22 INT304232 Protein_catabolism of TDD 1 0.64 0 0.1 99.68
23 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 99.62
24 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66 99.60
25 INT35744 Binding of MAOB 13 0.46 7.52 4.26 99.60
26 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 99.58
27 INT4609 Gene_expression of Klkb1 5 0.47 0.81 1.03 99.52
28 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.48
29 INT3889 Regulation of Serpinc1 13 0.61 8.6 3.46 99.42
30 INT38207 Positive_regulation of Tes 7 0.40 3.47 1.7 99.40
31 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.38
32 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.34
33 INT229207 Positive_regulation of HI 2 0.03 0.41 0.33 99.32
34 INT185519 Binding of Vms1 5 0.12 4.58 1.37 99.20
35 INT2038 Localization of Esr1 104 0.79 40.12 13.27 99.20
36 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 99.10
37 INT114412 Localization of HCL1 18 0.56 3.69 2.96 99.06
38 INT1703 Regulation of PCa 52 0.52 23.65 20.6 99.00
39 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 98.88
40 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 98.76
41 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58 98.76
42 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 98.76
43 INT176500 Negative_regulation of KLK5 3 0.26 0.41 0.24 98.72
44 INT4643 Negative_regulation of GHR 10 0.45 3.01 2 98.68
45 INT28299 Negative_regulation of Gene_expression of GHR 1 0.03 0.1 0.35 98.68
46 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 98.68
47 INT26860 Positive_regulation of Vms1 7 0.41 3.21 1.18 98.64
48 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 98.56
49 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 98.54
50 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 98.52
51 INT268834 Protein_catabolism of KLK5 1 0.15 0.08 0.35 98.50
52 INT56594 Positive_regulation of Localization of Il4 17 0.48 10.17 4.15 98.16
53 INT16165 Regulation of DMD 114 0.60 35.13 3.64 98.10
54 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66 98.08
55 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 98.00
56 INT20379 Localization of Il4 85 0.73 51.22 20.55 97.96
57 INT192686 Positive_regulation of Positive_regulation of DMD 8 0.41 4.66 0.93 97.88
58 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5 97.82
59 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 97.60
60 INT184803 Localization of TSC1 5 0.37 6.13 0.32 97.56
61 INT338126 Transcription of GET4 1 0.30 0.22 0.2 97.52
62 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94 97.48
63 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07 97.24
64 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34 97.24
65 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82 97.08
66 INT142735 Regulation of RLS 33 0.53 45.83 11.35 96.98
67 INT32688 Positive_regulation of Gene_expression of Shbg 14 0.45 7.01 1.6 96.96
68 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 96.96
69 INT22454 Regulation of Crp 213 0.62 160.67 49.24 96.88
70 INT11244 Transcription of CALCA 21 0.69 3.61 12.27 96.76
71 INT183046 Transcription of INS 25 0.70 11.14 1.13 96.76
72 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14 96.64
73 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 96.56
74 INT176497 Regulation of KLK5 2 0.28 0.45 0.22 96.52
75 INT695 Binding of POMC 304 0.48 56.66 126.85 96.48
76 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 96.32
77 INT26859 Negative_regulation of Vms1 10 0.29 3.05 1.37 96.30
78 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 96.28
79 INT7057 Binding of FAIM3 19 0.48 4.02 13.78 96.16
80 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31 96.12
81 INT82331 Positive_regulation of Positive_regulation of GHR 1 0.00 0.06 0.4 96.12
82 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 96.10
83 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 95.96
84 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4 95.96
85 INT40857 Positive_regulation of MAOA 6 0.49 2.51 1.71 95.92
86 INT264574 Positive_regulation of Negative_regulation of MAOA 1 0.37 0.05 0.41 95.92
87 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 95.80
88 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 95.76
89 INT82660 Negative_regulation of OTOR 3 0.38 1.6 0.69 95.76
90 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 95.72
91 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 95.52
92 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 95.52
93 INT289947 Binding of Git1 1 0.02 0 0.12 95.48
94 INT114 Binding of Oprl1 139 0.48 23 103.35 95.04
95 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67 94.84
96 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 94.72
97 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06 94.32
98 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 94.28
99 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 94.24
100 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 94.24
101 INT35406 Localization of Tnf 94 0.81 64.63 31.65 94.16
102 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44 94.16
103 INT282833 Regulation of Binding of TRH 1 0.22 0.13 0.11 93.76
104 INT108579 Localization of Nfasc 18 0.72 3.47 4 93.64
105 INT2774 Binding of Crp 241 0.48 195.89 44.39 93.48
106 INT847 Regulation of Lhb 131 0.61 22.08 46.54 93.40
107 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 93.32
108 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 93.28
109 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 93.24
110 INT147607 Binding of TERT 16 0.48 12.36 1.31 93.24
111 INT60977 Localization of CHN1 2 0.57 1.9 0.35 93.00
112 INT252 Localization of GH1 529 0.80 227.4 122.05 92.80
113 INT327200 Positive_regulation of Gene_expression of ESRRA 3 0.23 0.94 0.16 92.64
114 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 92.48
115 INT30683 Binding of TRH 4 0.36 0.96 1.55 92.40
116 INT68865 Gene_expression of ACOX1 13 0.52 5.49 2.09 92.12
117 INT50618 Gene_expression of Dio1 48 0.74 17.37 15.91 92.00
118 INT145888 Negative_regulation of Mthfd1 27 0.41 8.98 5.4 92.00
119 INT269719 Positive_regulation of Localization of FAIM3 1 0.17 0.22 2.36 91.92
120 INT269718 Localization of FAIM3 1 0.25 0.22 2.35 91.92
121 INT65661 Positive_regulation of Ado 13 0.52 4.75 8.54 91.88
122 INT184934 Positive_regulation of Sry 1 0.39 0.46 1.39 91.76
123 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45 91.56
124 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 91.52
125 INT1114 Localization of Ins1 748 0.80 192.95 165.48 91.40
126 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 91.12
127 INT152967 Localization of Ptz1b 1 0.55 0 0.66 91.08
128 INT180580 Binding of HEYL 7 0.17 4.49 1.15 91.04
129 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 90.90
130 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25 90.90
131 INT3546 Binding of Oxt 54 0.48 9.75 10.81 90.68
132 INT11807 Gene_expression of Il2 266 0.78 112 64.97 90.60
133 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95 90.48
134 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 90.32
135 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 90.32
136 INT75742 Binding of RLS 86 0.42 95.27 19.04 90.16
137 INT351213 Negative_regulation of Gene_expression of Commd3 1 0.17 0.46 0.43 90.00
138 INT93887 Gene_expression of ESRRA 4 0.40 2.63 0.36 89.92
139 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 89.88
140 INT114501 Transcription of MCPH1 4 0.43 0.71 0.79 89.84
141 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 89.84
142 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 89.64
143 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 89.52
144 INT132467 Transcription of SLCO1A2 1 0.69 0 0.69 89.44
145 INT10870 Regulation of IgG 67 0.59 43.27 12.74 89.32
146 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 89.04
147 INT122419 Transcription of ABCC1 10 0.70 4.45 4.61 88.96
148 INT135990 Positive_regulation of Gene_expression of Cd86 34 0.69 12.02 4.53 88.92
149 INT135991 Positive_regulation of Gene_expression of Cd80 19 0.54 6.9 1.71 88.92
150 INT116131 Gene_expression of Commd3 2 0.53 0.68 1.21 88.92
151 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 88.88
152 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 88.56
153 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 88.36
154 INT96157 Gene_expression of Cd80 74 0.77 31.19 9.78 88.36
155 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14 88.00
156 INT39394 Regulation of Ren1 13 0.45 4.83 2.4 87.96
157 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 87.44
158 INT338125 Gene_expression of GET4 1 0.29 2.74 0.32 87.40
159 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 87.40
160 INT83734 Negative_regulation of RLS 24 0.50 35.75 5.66 87.28
161 INT4148 Gene_expression of HRH1 11 0.77 2.71 4.22 87.24
162 INT2415 Binding of MAOA 26 0.47 13.26 11.86 87.12
163 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 87.04
164 INT5913 Binding of OPA1 12 0.41 9.33 2.92 86.96
165 INT14513 Localization of Ghrl 52 0.78 29.26 11.63 86.88
166 INT10284 Binding of ORM1 16 0.48 0.98 7.73 86.80
167 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 86.44
168 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 86.40
169 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 86.40
170 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 86.28
171 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 86.08
172 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 85.80
173 INT179656 Gene_expression of Elane 12 0.32 9.44 3.53 85.44
174 INT203132 Negative_regulation of Gene_expression of Elane 1 0.20 1.5 0.86 85.44
175 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 85.40
176 INT84812 Negative_regulation of Positive_regulation of Ado 1 0.33 0.55 1.81 85.32
177 INT84810 Positive_regulation of Positive_regulation of Ado 2 0.35 0.36 0.9 85.32
178 INT101889 Negative_regulation of DSP 3 0.42 1.61 1.05 85.20
179 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84 85.08
180 INT39632 Regulation of Localization of NA 8 0.20 1.52 1.81 85.08
181 INT5743 Localization of NA 104 0.59 14.35 35.29 85.08
182 INT81881 Negative_regulation of SPG21 1 0.41 0.41 0.13 84.40
183 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 84.24
184 INT35254 Negative_regulation of SERPINB1 22 0.48 11.42 4.7 83.80
185 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 83.72
186 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 83.56
187 INT58643 Positive_regulation of HMI 10 0.50 6.59 3.5 83.52
188 INT304233 Binding of TDD 1 0.27 0 0.08 83.20
189 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 83.20
190 INT9729 Negative_regulation of LHB 14 0.42 1.86 4.63 82.92
191 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 82.92
192 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 82.76
193 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 82.60
194 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 82.60
195 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 82.60
196 INT81904 Positive_regulation of FDPS 5 0.67 2.83 0.85 82.56
197 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 82.48
198 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 82.32
199 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 82.28
200 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 82.24
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