P:tricyclic antidepressant

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Drug class
Synonyms Tricyclic Antidepressants
Pain Specific No
Documents 2029
Hot Single Events 200
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for tricyclic antidepressant. They are ordered first by their pain relevance and then by number of times they were reported for tricyclic antidepressant. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 100.00
2 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67 100.00
3 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92 84.28
4 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96 84.28
5 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96 84.28
6 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91 84.08
7 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81 76.24
8 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29 74.72
9 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29 74.72
10 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 71.12
11 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 71.12
12 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49 68.16
13 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 64.88
14 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 64.88
15 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53 64.40
16 INT149468 Avp Positive_regulation of Localization of Mc2r 1 0.07 0.26 0.21 64.40
17 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33 62.80
18 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 62.16
19 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78 60.92
20 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77 60.92
21 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53 57.84
22 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 57.60
23 INT97868 Binding of Chrna2 and Regulation of Acot1 1 0.09 0 0.23 57.32
24 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 56.24
25 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 53.92
26 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1 53.40
27 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 50.36
28 INT210551 Binding of KCNH2 and KCNE2 1 0.08 0 0.19 50.00
29 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27 48.56
30 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 48.40
31 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 42.16
32 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 39.84
33 INT277803 Regulation of GNRH1 Regulation of CGA 1 0.00 0.61 0 39.84
34 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 33.12
35 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45 31.04
36 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85 25.36
37 INT20482 POMC Positive_regulation of CCK 1 0.20 0 0.21 25.00
38 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 24.12
39 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 23.12
40 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29 14.00
41 INT237728 CDR1 Regulation of ADHD1 1 0.03 0.98 0 12.08
42 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
43 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
44 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 5.00
45 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
46 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
47 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73 5.00
48 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 5.00
49 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
50 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
51 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
52 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29 5.00
53 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
54 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
55 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27 5.00
56 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
57 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
58 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
59 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76 5.00
60 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76 5.00
61 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 5.00
62 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
63 INT195545 Rel Regulation of Gene_expression of Grm3 1 0.01 0.46 0.71 5.00
64 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71 5.00
65 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 5.00
66 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
67 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
68 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 5.00
69 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
70 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
71 INT192873 Binding of RS1 and Nktcn1 1 0.00 0.8 0.59 5.00
72 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 5.00
73 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 5.00
74 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54 5.00
75 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
76 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
77 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52 5.00
78 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52 5.00
79 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52 5.00
80 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51 5.00
81 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51 5.00
82 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45 5.00
83 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45 5.00
84 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45 5.00
85 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45 5.00
86 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
87 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43 5.00
88 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43 5.00
89 INT315333 Binding of Cflar and Fadd 1 0.01 0.49 0.42 5.00
90 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
91 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4 5.00
92 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4 5.00
93 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4 5.00
94 INT291449 Car2 Positive_regulation of SK 1 0.03 0 0.39 5.00
95 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
96 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
97 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36 5.00
98 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 5.00
99 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 5.00
100 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
101 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
102 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
103 INT290826 Binding of hpc and Cort Positive_regulation of hpc 1 0.00 0.79 0.32 5.00
104 INT290854 Binding of hpc and Cort 1 0.01 0.79 0.32 5.00
105 INT290853 Cort Positive_regulation of hpc 1 0.01 0.79 0.32 5.00
106 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
107 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
108 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28 5.00
109 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28 5.00
110 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
111 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27 5.00
112 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26 5.00
113 INT291446 Bdnf Positive_regulation of Positive_regulation of Ltp 1 0.02 0 0.26 5.00
114 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
115 INT264569 Binding of STS and ATF7IP 1 0.03 0.15 0.25 5.00
116 INT290847 Regulation of Binding of Stx1a and Fig4 1 0.05 0.26 0.24 5.00
117 INT195544 Lct Positive_regulation of Transcription of Grm2 1 0.01 0.06 0.24 5.00
118 INT195547 Lct Positive_regulation of Transcription of Grm3 1 0.00 0.06 0.24 5.00
119 INT195553 Lct Positive_regulation of Grm2 1 0.02 0.05 0.23 5.00
120 INT291448 Prkaca Regulation of Gene_expression of Kcnn2 1 0.04 0 0.23 5.00
121 INT195548 Lct Positive_regulation of Grm3 1 0.00 0.06 0.23 5.00
122 INT291447 Bdnf Positive_regulation of Prkaca 1 0.04 0 0.23 5.00
123 INT290846 Binding of Stx1a and Fig4 1 0.07 0.26 0.22 5.00
124 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 5.00
125 INT177477 Crh Positive_regulation of Crh Regulation of POMC 1 0.02 0.86 0.22 5.00
126 INT290857 PPR Regulation of Fig4 1 0.02 0.45 0.21 5.00
127 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21 5.00
128 INT290855 PPR Regulation of Ca2 1 0.01 0.45 0.2 5.00
129 INT184868 Binding of Slc6a3 and Lmo1 1 0.02 0.72 0.19 5.00
130 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18 5.00
131 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18 5.00
132 INT290858 Positive_regulation of Ca2 Regulation of PPR 1 0.01 0.5 0.18 5.00
133 INT290856 Ca2 Regulation of PPR 1 0.01 0.5 0.18 5.00
134 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 5.00
135 INT274353 DST Regulation of Gopc 1 0.00 0 0.17 5.00
136 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
137 INT177480 Positive_regulation of Crh Positive_regulation of Regulation of POMC 1 0.06 0.46 0.14 5.00
138 INT321181 Binding of Ntrk2 and Ntf5 1 0.09 0.08 0.14 5.00
139 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14 5.00
140 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 5.00
141 INT200099 OLR1 Negative_regulation of Gene_expression of VCAM1 1 0.01 0.85 0.13 5.00
142 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
143 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11 5.00
144 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 5.00
145 INT200213 PAH Positive_regulation of SDHD 1 0.21 2.43 0.1 5.00
146 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1 5.00
147 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09 5.00
148 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 5.00
149 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09 5.00
150 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09 5.00
151 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09 5.00
152 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09 5.00
153 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 5.00
154 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09 5.00
155 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09 5.00
156 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09 5.00
157 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09 5.00
158 INT208979 Binding of Itpr3 and Trpc3 1 0.00 0.33 0.09 5.00
159 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 5.00
160 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08 5.00
161 INT291450 Kcnn3 Negative_regulation of Gene_expression of SK 1 0.10 0.53 0.08 5.00
162 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 5.00
163 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
164 INT195549 Lct Positive_regulation of Rela 1 0.01 0 0.07 5.00
165 INT208989 Binding of CALM1 and Fig4 1 0.01 0 0.07 5.00
166 INT273947 Binding of Gabra1 and Mrvi1 1 0.00 0.94 0.07 5.00
167 INT273936 Binding of Crem and Mrvi1 1 0.00 0.94 0.07 5.00
168 INT273937 Binding of Crem and Gabra1 1 0.30 0.94 0.07 5.00
169 INT195556 Smc2 Regulation of Gene_expression of Grm3 1 0.01 0 0.06 5.00
170 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06 5.00
171 INT195550 Smc2 Regulation of Gene_expression of Grm2 1 0.02 0 0.06 5.00
172 INT195551 Lct Regulation of Gene_expression of Grm2 1 0.01 0 0.05 5.00
173 INT208988 Binding of CALM1 and Itpr3 1 0.01 0.15 0.05 5.00
174 INT291451 Binding of CALM1 and Car2 1 0.00 0 0.05 5.00
175 INT273944 Negative_regulation of Creb1 Positive_regulation of Positive_regulation of Crem 1 0.26 0.62 0.05 5.00
176 INT200212 Binding of EPAS1 and VHL 3 0.06 4.1 0.05 5.00
177 INT208982 Negative_regulation of Binding of Itpr3 and Trpc3 1 0.00 0.17 0.04 5.00
178 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04 5.00
179 INT195546 Smc2 Regulation of Transcription of Grm2 1 0.02 0 0.03 5.00
180 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03 5.00
181 INT282503 Binding of ocd and Dlgap3 1 0.28 1.58 0.03 5.00
182 INT195543 Smc2 Regulation of Transcription of Grm3 1 0.01 0 0.03 5.00
183 INT273946 Phosphorylation of Creb1 Positive_regulation of Gene_expression of Crem 1 0.29 0 0 5.00
184 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0 5.00
185 INT273938 Creb1 Positive_regulation of Transcription of Mirg 1 0.01 0.06 0 5.00
186 INT273948 Binding of Creb1 and Pmp2 1 0.04 0 0 5.00
187 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0 5.00
188 INT345505 E2f1 Positive_regulation of PMAIP1 1 0.18 0.62 0 5.00
189 INT336480 Binding of Pln and RLS 1 0.02 0.34 0 5.00
190 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0 5.00
191 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0 5.00
192 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0 5.00
193 INT273952 Creb1 Positive_regulation of Pmp2 1 0.09 0.06 0 5.00
194 INT345485 Binding of MCL1 and BBC3 1 0.01 0.79 0 5.00
195 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0 5.00
196 INT273949 Binding of Crem and Smarca4 1 0.01 0 0 5.00
197 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0 5.00
198 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0 5.00
199 INT321179 Negative_regulation of Binding of Bdnf and Ntrk2 1 0.38 0 0 5.00
200 INT273950 Binding of Crem and Cst8 1 0.10 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for tricyclic antidepressant. They are ordered first by their pain relevance and then by number of times they were reported in tricyclic antidepressant. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT56775 Binding of Htr2c 16 0.47 3.77 8.74 100.00
2 INT88571 Positive_regulation of Tcas1 4 0.34 2.08 4.42 100.00
3 INT242353 Binding of Tcas1 3 0.03 3.31 2.22 100.00
4 INT2415 Binding of MAOA 26 0.47 13.26 11.86 100.00
5 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
6 INT29280 Negative_regulation of Tcas1 2 0.03 0.77 1.78 100.00
7 INT120865 Regulation of Cyp3a62 5 0.62 0.07 3.4 100.00
8 INT92732 Gene_expression of Tcas1 2 0.05 0.34 1.83 100.00
9 INT922 Regulation of Positive_regulation of PRL 7 0.60 3.57 3.95 100.00
10 INT4616 Regulation of Maoa 40 0.62 6.09 15.94 100.00
11 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83 100.00
12 INT79699 Regulation of Cyp2a 1 0.55 0.46 1.62 100.00
13 INT163272 Gene_expression of SSR1 2 0.65 0.23 0.56 100.00
14 INT154727 Regulation of Cyp2b2 2 0.25 0 1.76 100.00
15 INT335 Binding of Adra1a 16 0.36 6.16 6 100.00
16 INT35366 Binding of AR 87 0.47 30.52 8.9 100.00
17 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56 100.00
18 INT27258 Regulation of Htr2a 18 0.60 6.37 11.06 100.00
19 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53 100.00
20 INT133835 Regulation of Cyp2c6 1 0.45 0 0.69 100.00
21 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 99.98
22 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 99.98
23 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 99.98
24 INT23229 Positive_regulation of H2-M3 11 0.04 1.87 8.56 99.96
25 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.96
26 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 99.96
27 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 99.92
28 INT6882 Binding of Adrb2 5 0.47 1.97 3.55 99.92
29 INT235710 Binding of SSR1 2 0.36 0.86 1.75 99.90
30 INT15348 Positive_regulation of Localization of Prl 6 0.70 1.16 4.31 99.90
31 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 99.88
32 INT146987 Negative_regulation of KIR2DS4 1 0.02 0 3.32 99.84
33 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 99.84
34 INT296914 Regulation of Pln 2 0.19 3.08 1.23 99.84
35 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 99.82
36 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 99.80
37 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 99.76
38 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93 99.76
39 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 99.76
40 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.76
41 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 99.76
42 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 99.76
43 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 99.76
44 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96 99.76
45 INT15350 Localization of Prl 22 0.81 6.86 10.74 99.76
46 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.66
47 INT26640 Regulation of Pigm 17 0.35 3.94 7.02 99.62
48 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 99.60
49 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.60
50 INT167456 Regulation of Gene_expression of Nr3c1 2 0.14 0.76 1.87 99.60
51 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73 99.60
52 INT240206 Negative_regulation of RBX1 1 0.08 0.15 0.51 99.60
53 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48 99.52
54 INT47914 Regulation of Il2ra 5 0.18 3.05 1.86 99.52
55 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14 99.48
56 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.46
57 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 99.44
58 INT40469 Negative_regulation of Olr1746 3 0.57 0.48 1.53 99.32
59 INT144364 Negative_regulation of Lmx1b 5 0.45 3.35 2.12 99.32
60 INT70069 Positive_regulation of KNCN 1 0.03 0.59 0.74 99.22
61 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 99.22
62 INT244600 Negative_regulation of POSTN 5 0.18 3.12 1.64 99.20
63 INT321199 Binding of POSTN 2 0.31 1.94 0.62 99.20
64 INT345502 Positive_regulation of Binding of POSTN 1 0.07 0.93 0.62 99.20
65 INT262366 Localization of Adh4 1 0.78 1.88 1 99.18
66 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 99.16
67 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 99.12
68 INT17668 Positive_regulation of MCKD1 5 0.02 1.56 3.91 99.10
69 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 99.08
70 INT141452 Negative_regulation of Binding of ABAT 4 0.37 1.41 3.17 99.08
71 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.06
72 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3 99.06
73 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 98.96
74 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 98.96
75 INT21185 Binding of Ptprg 213 0.47 13.49 157.75 98.92
76 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 98.92
77 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 98.92
78 INT55222 Negative_regulation of Gene_expression of Qrfp 5 0.24 1.01 2.72 98.92
79 INT151111 Gene_expression of Pain1 33 0.40 33.6 30.73 98.90
80 INT32903 Negative_regulation of PPAP2A 14 0.48 5.02 7.2 98.84
81 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 98.84
82 INT18621 Binding of ABAT 28 0.36 9.88 18.04 98.84
83 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 98.80
84 INT123419 Binding of NAV1 37 0.48 7.09 26.43 98.80
85 INT18332 Regulation of Glra2 3 0.25 0.13 1.87 98.80
86 INT29583 Positive_regulation of Agtr2 30 0.45 21.47 7.04 98.78
87 INT425 Localization of PRL 455 0.81 189.64 144.8 98.70
88 INT87794 Positive_regulation of Mors1 19 0.38 4.74 20.23 98.68
89 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05 98.60
90 INT61238 Negative_regulation of Cyp2d2 4 0.58 0 6.38 98.58
91 INT107396 Negative_regulation of Gene_expression of Cyp2d2 1 0.43 0 0.84 98.58
92 INT57721 Localization of CCT6A 2 0.16 3.12 5.88 98.56
93 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 98.48
94 INT94132 Binding of ACOT1 7 0.13 2.62 4.04 98.44
95 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 98.40
96 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 98.38
97 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 98.36
98 INT4148 Gene_expression of HRH1 11 0.77 2.71 4.22 98.36
99 INT49731 Transcription of Agtr2 4 0.44 0.95 2.06 98.34
100 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 98.32
101 INT70521 Regulation of Kcna1 2 0.50 0.54 1.11 98.32
102 INT58123 Gene_expression of Cyp2d2 4 0.62 0 2.43 98.30
103 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 98.28
104 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 98.28
105 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 98.20
106 INT1218 Negative_regulation of Maob 24 0.59 9.76 9.39 98.16
107 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97 98.16
108 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 98.12
109 INT129492 Gene_expression of Hpse 11 0.75 6.56 1.59 98.08
110 INT7716 Positive_regulation of Positive_regulation of Adra2a 9 0.68 0.8 4.69 98.08
111 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 98.08
112 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 98.08
113 INT105746 Regulation of ECT 22 0.39 7.6 7.47 98.06
114 INT546 Binding of ALB 311 0.48 85.98 60.14 98.04
115 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5 98.04
116 INT9842 Binding of F2 36 0.47 22.79 4.42 98.04
117 INT115 Negative_regulation of Maoa 65 0.59 16.27 38.66 97.98
118 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23 97.96
119 INT137673 Gene_expression of Fdx1 1 0.54 0.1 0.31 97.96
120 INT26116 Gene_expression of Gpr156 31 0.78 13.97 20.59 97.88
121 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17 97.84
122 INT44 Positive_regulation of Adra1a 30 0.68 7.09 12.73 97.84
123 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96 97.80
124 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77 97.80
125 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 97.76
126 INT92736 Positive_regulation of Positive_regulation of Slurp1 1 0.13 0.07 1.02 97.76
127 INT11246 Binding of Grin1 65 0.48 14.53 36.93 97.76
128 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 97.76
129 INT29086 Negative_regulation of Sert1 37 0.58 7.49 14.98 97.74
130 INT78817 Binding of Scnn1a 2 0.35 0 0.48 97.72
131 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 97.68
132 INT110549 Negative_regulation of CYP2C8 15 0.59 0.54 4.78 97.64
133 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 97.64
134 INT19488 Localization of ABAT 56 0.69 21.51 50.56 97.64
135 INT1530 Regulation of Gh 382 0.61 115.96 112.47 97.62
136 INT50580 Binding of PPIG 39 0.36 11.17 12.34 97.60
137 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 97.56
138 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 97.56
139 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78 97.52
140 INT32176 Negative_regulation of Negative_regulation of Adrb1 2 0.40 0.4 1.77 97.52
141 INT117893 Binding of Serpind1 15 0.41 24.59 2.41 97.52
142 INT112144 Negative_regulation of Nrg2 5 0.53 1.27 3.52 97.40
143 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 97.32
144 INT5324 Binding of Htr2a 23 0.47 7.14 14.66 97.28
145 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53 97.28
146 INT18778 Gene_expression of Ugt1a2 17 0.35 9.91 6.87 97.22
147 INT92189 Positive_regulation of Slurp1 4 0.18 1.84 3.01 97.20
148 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 97.16
149 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93 97.16
150 INT50290 Binding of Cpox 29 0.27 17.19 8.01 97.16
151 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 97.06
152 INT70816 Negative_regulation of Fos 32 0.58 13 11.18 97.04
153 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 96.92
154 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.88
155 INT70522 Binding of Kcna1 2 0.36 0.73 2.22 96.88
156 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 96.84
157 INT75908 Regulation of LEP 77 0.60 60.16 15.19 96.84
158 INT106583 Negative_regulation of Transcription of Rabif 1 0.42 0.2 1.59 96.80
159 INT151661 Regulation of Negative_regulation of gr 1 0.39 0.13 0.66 96.80
160 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 96.78
161 INT87822 Binding of Cyp1a2 8 0.47 0.84 2.72 96.78
162 INT10166 Localization of Tnf 237 0.81 153.95 88.64 96.72
163 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 96.72
164 INT11669 Gene_expression of Htr2a 17 0.75 6.78 10.75 96.72
165 INT49843 Positive_regulation of Gene_expression of Htr2a 3 0.49 1.53 2.84 96.72
166 INT49842 Regulation of Gene_expression of Htr2a 2 0.44 0.18 0.88 96.72
167 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61 96.68
168 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 96.64
169 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 96.60
170 INT16764 Transcription of Qrfp 39 0.69 6.29 21.61 96.60
171 INT58121 Binding of Cyp2d2 2 0.37 0 1.59 96.60
172 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 96.58
173 INT296661 Positive_regulation of Cds1 1 0.40 1.33 4.45 96.58
174 INT267806 Negative_regulation of Pln 8 0.40 4.01 1.63 96.58
175 INT81388 Localization of Xpr1 6 0.55 2.26 2.09 96.56
176 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64 96.56
177 INT9711 Binding of TOC 2 0.32 0 0.62 96.48
178 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 96.42
179 INT75421 Regulation of Binding of Ptprg 13 0.44 0.96 12.64 96.40
180 INT40034 Localization of Maoa 7 0.80 2.17 3.69 96.40
181 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58 96.40
182 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 96.36
183 INT75497 Regulation of JUN 28 0.61 11.04 7.09 96.36
184 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 96.28
185 INT93193 Positive_regulation of Accn2 16 0.69 7.2 6.37 96.24
186 INT12440 Regulation of Gpr156 11 0.45 3.2 6.07 96.24
187 INT118124 Binding of USE1 24 0.16 16.64 5.44 96.16
188 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 96.16
189 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84 96.16
190 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08 96.16
191 INT123705 Gene_expression of SMARCB1 40 0.73 19.47 2.2 96.10
192 INT55185 Binding of Sert1 26 0.48 4.43 7.57 96.08
193 INT9660 Regulation of TNF 363 0.62 312.94 139.99 96.00
194 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 96.00
195 INT53395 Positive_regulation of Cyp2c6 6 0.70 0.07 3.73 95.96
196 INT1782 Regulation of Gh1 125 0.62 22 55.74 95.88
197 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 95.84
198 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 95.84
199 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 95.84
200 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 95.64
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox