P:trk B

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pChart

Pain Term
Category Molecule
Synonyms None
Pain Specific No
Documents 6
Hot Single Events 28
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for trk B. They are ordered first by their pain relevance and then by number of times they were reported for trk B. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT300876 Bdnf Positive_regulation of NTRK2 1 0.01 0.27 0.15 100.00
2 INT300875 Ngf Positive_regulation of NTRK2 1 0.01 0.27 0.15 100.00
3 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 99.78
4 INT300861 Ngf Positive_regulation of Ntrk2 1 0.29 0.27 0.15 99.78
5 INT300853 Ngf Positive_regulation of Fgf2 1 0.14 0.18 0.12 79.04
6 INT300858 Ngf Positive_regulation of Il6 1 0.17 0.24 0.12 79.04
7 INT300860 Bdnf Positive_regulation of Fgf2 1 0.08 0.18 0.12 78.40
8 INT300872 Bdnf Positive_regulation of Il6 1 0.09 0.24 0.12 78.40
9 INT300857 Il6 Positive_regulation of Bdnf 1 0.09 0.3 0.12 63.84
10 INT300859 Il6 Positive_regulation of Ngf 1 0.18 0.3 0.12 63.12
11 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74 62.32
12 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
13 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
14 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42 5.00
15 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42 5.00
16 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 5.00
17 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
18 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
19 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
20 INT300855 Il1 Regulation of Il6 1 0.01 0.81 0.3 5.00
21 INT318620 Mog Regulation of Mbp 1 0.05 0.85 0.23 5.00
22 INT321181 Binding of Ntrk2 and Ntf5 1 0.09 0.08 0.14 5.00
23 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14 5.00
24 INT300867 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of Il6 1 0.02 0.42 0.08 5.00
25 INT300869 Ntrk2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.16 0.08 5.00
26 INT300870 Bdnf Positive_regulation of Gene_expression of Il6 1 0.10 0 0.05 5.00
27 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03 5.00
28 INT300874 Ngf Positive_regulation of NTRK1 1 0.07 0 0 5.00
29 INT300854 Ngf Positive_regulation of Positive_regulation of Il6 1 0.18 0.06 0 5.00
30 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0 5.00
31 INT300862 Bdnf Positive_regulation of Mapk14 1 0.02 0.11 0 5.00
32 INT321179 Negative_regulation of Binding of Bdnf and Ntrk2 1 0.38 0 0 5.00
33 INT300863 Bdnf Positive_regulation of Mapk1 1 0.02 0.11 0 5.00
34 INT300877 Negative_regulation of AKT1 Negative_regulation of Il6 1 0.04 0.16 0 5.00
35 INT300866 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of Ngf 1 0.03 0 0 5.00
36 INT300856 Bdnf Positive_regulation of Positive_regulation of Il6 1 0.09 0.06 0 5.00
37 INT300873 Positive_regulation of Ngf Positive_regulation of NTRK1 1 0.07 0 0 5.00
38 INT300865 Ngf Positive_regulation of Gene_expression of Il6 1 0.17 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for trk B. They are ordered first by their pain relevance and then by number of times they were reported in trk B. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT101147 Gene_expression of Uchl1 31 0.76 14.73 13.22 100.00
2 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 100.00
3 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37 100.00
4 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14 100.00
5 INT67116 Gene_expression of Ntrk3 20 0.59 7.64 8.94 100.00
6 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.80
7 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 99.36
8 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 98.68
9 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 98.56
10 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75 97.68
11 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 97.48
12 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 96.56
13 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64 96.20
14 INT129157 Positive_regulation of Atf3 48 0.69 35.42 22.87 96.20
15 INT36549 Gene_expression of Ociad1 6 0.59 1.42 1.29 93.36
16 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 92.80
17 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45 91.68
18 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 89.84
19 INT300848 Negative_regulation of Cxcl12 3 0.40 2.29 0.69 87.92
20 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63 87.36
21 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71 86.72
22 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43 86.16
23 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 84.28
24 INT300851 Negative_regulation of Positive_regulation of Fgf2 3 0.42 1.01 0.4 84.00
25 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18 83.20
26 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29 82.88
27 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84 82.88
28 INT120603 Negative_regulation of Cntf 6 0.35 3.57 0.78 82.88
29 INT8423 Gene_expression of Cntf 29 0.69 11.69 8.4 78.88
30 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7 78.88
31 INT202906 Negative_regulation of Atf3 2 0.43 5.65 1.17 75.76
32 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 73.68
33 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 71.12
34 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 69.84
35 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 67.68
36 INT81458 Positive_regulation of Cntf 11 0.47 4.18 3.18 63.04
37 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9 63.04
38 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 60.96
39 INT8422 Binding of Cntf 8 0.37 4.54 1.72 56.24
40 INT299519 Binding of Lif 2 0.21 0.67 0.29 54.08
41 INT318610 Positive_regulation of Binding of Lif 1 0.28 0.67 0.19 54.08
42 INT22499 Regulation of Calca 42 0.62 17.32 28.02 50.84
43 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 43.92
44 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 41.84
45 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 41.84
46 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 41.84
47 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42 41.84
48 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76 37.52
49 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2 37.52
50 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 37.12
51 INT8690 Localization of Tac1 71 0.80 22.98 50.75 36.56
52 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 35.44
53 INT50392 Regulation of Ret 6 0.54 3.51 2.22 29.12
54 INT20586 Regulation of Gfra1 20 0.51 9.43 3.41 28.48
55 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43 27.92
56 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 23.88
57 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 23.88
58 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 23.88
59 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 21.96
60 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75 21.96
61 INT202907 Localization of Atf3 3 0.75 1.26 1.03 21.96
62 INT159728 Localization of Uchl1 2 0.73 0.54 0.8 21.96
63 INT20422 Regulation of Gap43 10 0.61 5.24 3.73 19.60
64 INT202908 Binding of Uchl1 1 0.08 0.27 0.4 18.72
65 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62 18.24
66 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
67 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
68 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
69 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 5.00
70 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 5.00
71 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
72 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 5.00
73 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
74 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 5.00
75 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
76 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 5.00
77 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 5.00
78 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 5.00
79 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
80 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 5.00
81 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 5.00
82 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
83 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 5.00
84 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
85 INT19511 Localization of Il6 212 0.81 118.17 67.67 5.00
86 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 5.00
87 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
88 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
89 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 5.00
90 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 5.00
91 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
92 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
93 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 5.00
94 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
95 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98 5.00
96 INT20210 Localization of Ngf 69 0.79 46.22 38.57 5.00
97 INT223416 Gene_expression of Trhde 2 0.48 64.16 34.21 5.00
98 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 5.00
99 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
100 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
101 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18 5.00
102 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 5.00
103 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 5.00
104 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 5.00
105 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83 5.00
106 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 5.00
107 INT20585 Gene_expression of Gfra1 39 0.77 26.94 26.69 5.00
108 INT63769 Regulation of Ngf 44 0.62 21.82 25.84 5.00
109 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
110 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 5.00
111 INT113925 Localization of Bdnf 59 0.79 24.03 22.76 5.00
112 INT310853 Positive_regulation of Gene_expression of Trhde 1 0.43 42.95 22.75 5.00
113 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 5.00
114 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77 5.00
115 INT49985 Transcription of Il6 62 0.72 40.13 20.29 5.00
116 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8 5.00
117 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
118 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
119 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15 5.00
120 INT8392 Regulation of Gene_expression of Qrfp 37 0.54 6.9 19.02 5.00
121 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 5.00
122 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64 5.00
123 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29 5.00
124 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23 5.00
125 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11 5.00
126 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 5.00
127 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94 5.00
128 INT86790 Gene_expression of P2rx6 34 0.74 14.04 15.92 5.00
129 INT93482 Localization of Rela 56 0.78 24.52 14.82 5.00
130 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 5.00
131 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
132 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67 5.00
133 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 5.00
134 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37 5.00
135 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25 5.00
136 INT310842 Gene_expression of Pgpep1 1 0.32 28.03 11.64 5.00
137 INT27687 Regulation of Cp 20 0.53 9.75 10.8 5.00
138 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17 5.00
139 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 5.00
140 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1 5.00
141 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09 5.00
142 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69 5.00
143 INT10241 Positive_regulation of Gap43 26 0.70 9.89 8.54 5.00
144 INT27050 Positive_regulation of Trhde 2 0.43 14.07 8.23 5.00
145 INT75684 Regulation of Aif1 32 0.47 8.03 7.89 5.00
146 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 5.00
147 INT20423 Positive_regulation of Gene_expression of Gap43 16 0.70 6.63 6.8 5.00
148 INT73155 Positive_regulation of Positive_regulation of Ngf 11 0.70 5.11 6.7 5.00
149 INT129015 Phosphorylation of Ngf 6 0.73 5.92 6.6 5.00
150 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3 5.00
151 INT19995 Gene_expression of Prph 16 0.75 8.11 5.52 5.00
152 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51 5.00
153 INT163913 Gene_expression of Il11ra1 18 0.69 12.62 5.34 5.00
154 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28 5.00
155 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05 5.00
156 INT126505 Positive_regulation of Ntf3 26 0.70 9.17 4.92 5.00
157 INT118476 Positive_regulation of Rpl3 6 0.37 5.93 4.79 5.00
158 INT479 Positive_regulation of Gfra1 25 0.69 10.71 4.76 5.00
159 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52 5.00
160 INT106778 Regulation of Gene_expression of P2rx6 5 0.34 4.3 4.38 5.00
161 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3 5.00
162 INT310855 Positive_regulation of Gene_expression of Pgpep1 1 0.29 10.67 4.25 5.00
163 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 5.00
164 INT158416 Localization of Mapk1 19 0.67 5.32 4.18 5.00
165 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07 5.00
166 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06 5.00
167 INT50295 Regulation of Mtpn 13 0.26 7.54 3.77 5.00
168 INT80550 Positive_regulation of Gene_expression of Asap1 8 0.42 5.8 3.09 5.00
169 INT255307 Phosphorylation of Mgst1 5 0.14 0.12 3.05 5.00
170 INT298246 Positive_regulation of Ntrk3 7 0.48 3.81 3.01 5.00
171 INT16287 Positive_regulation of NOVA2 25 0.49 6.62 3.01 5.00
172 INT310844 Localization of Trhde 1 0.47 4.78 2.82 5.00
173 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82 5.00
174 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 5.00
175 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77 5.00
176 INT143841 Positive_regulation of Mtpn 17 0.17 5.46 2.68 5.00
177 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61 5.00
178 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52 5.00
179 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41 5.00
180 INT86426 Gene_expression of Hspb1 16 0.78 10.86 2.26 5.00
181 INT107102 Negative_regulation of Positive_regulation of Ntrk2 6 0.54 1.61 2.21 5.00
182 INT310848 Positive_regulation of Pgpep1 1 0.29 4.42 2.09 5.00
183 INT310837 Regulation of Gene_expression of Pgpep1 1 0.19 3.59 2.07 5.00
184 INT310841 Regulation of Gene_expression of Trhde 1 0.28 3.43 1.95 5.00
185 INT51368 Regulation of Sub1 1 0.09 1.95 1.86 5.00
186 INT57663 Gene_expression of Rpl3 3 0.50 2.05 1.83 5.00
187 INT101476 Binding of P2rx6 4 0.24 1.04 1.78 5.00
188 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74 5.00
189 INT69026 Gene_expression of Mog 4 0.45 6.9 1.68 5.00
190 INT105200 Binding of Ntf3 6 0.31 2.46 1.67 5.00
191 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64 5.00
192 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64 5.00
193 INT89167 Positive_regulation of Gene_expression of Mgst1 11 0.69 2.09 1.53 5.00
194 INT27045 Protein_catabolism of Trhde 2 0.61 2.44 1.46 5.00
195 INT207005 Regulation of Localization of Bdnf 6 0.45 3.85 1.45 5.00
196 INT142241 Positive_regulation of Positive_regulation of Ntrk2 3 0.66 0.87 1.43 5.00
197 INT155699 Phosphorylation of Bdnf 5 0.81 1.49 1.37 5.00
198 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15 5.00
199 INT101950 Gene_expression of Crhq1 3 0.68 1.26 1.1 5.00
200 INT3414 Positive_regulation of Negative_regulation of Alb 4 0.44 1.91 1.09 5.00
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