P:withdrawal

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pChart

Pain Term
Category Condition
Synonyms None
Pain Specific No
Documents 12421
Hot Single Events 200
Hot Interactions 191

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for withdrawal. They are ordered first by their pain relevance and then by number of times they were reported for withdrawal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63 100.00
2 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58 100.00
3 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58 100.00
4 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5 100.00
5 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3 100.00
6 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3 100.00
7 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21 100.00
8 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52 100.00
9 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96 100.00
10 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 100.00
11 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11 99.98
12 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62 99.98
13 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88 99.96
14 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61 99.82
15 INT44838 Pitpnm1 Negative_regulation of Th 1 0.02 0 1.09 99.72
16 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24 99.64
17 INT152111 IL1B Negative_regulation of Ltp 1 0.03 0.85 0.66 99.62
18 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38 99.52
19 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64 99.04
20 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65 98.84
21 INT127437 deltaFosB Negative_regulation of Vta1 1 0.01 0.09 1.06 98.64
22 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23 98.56
23 INT148563 Ngf Positive_regulation of GNAS 1 0.06 0.07 0.16 98.56
24 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2 98.40
25 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11 98.20
26 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58 98.20
27 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06 98.20
28 INT107933 Oprm1 Positive_regulation of Gene_expression of Mastl 1 0.33 0.61 0.71 98.16
29 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89 98.00
30 INT142129 Nrgn Regulation of Camk2a 1 0.48 0.25 0.89 98.00
31 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12 97.96
32 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87 97.92
33 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85 97.80
34 INT52632 Binding of TSPO and CCK 1 0.15 0.53 0.37 97.68
35 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9 97.44
36 INT137535 Prl Positive_regulation of Phosphorylation of Trpv1 1 0.56 0.11 0.57 97.44
37 INT137534 Prl Positive_regulation of Trpv1 1 0.78 0.11 0.57 97.44
38 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11 97.40
39 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52 97.24
40 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31 97.16
41 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28 97.08
42 INT212661 KCNA1 Positive_regulation of Scort1 1 0.00 0.91 1.03 97.00
43 INT222557 Gal Positive_regulation of Gene_expression of Vip 1 0.06 0.07 0.25 96.92
44 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 96.88
45 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64 96.64
46 INT291545 Binding of Dlat and St8sia2 1 0.14 0.44 0.37 96.52
47 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58 96.48
48 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57 96.48
49 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57 96.48
50 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 96.28
51 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13 96.24
52 INT59379 Calca Negative_regulation of Vip 1 0.12 0.67 0.12 96.24
53 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18 96.04
54 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85 96.04
55 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85 96.04
56 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08 95.88
57 INT238397 EID1 Regulation of E2F2 1 0.00 0.36 0.08 95.88
58 INT316371 Ang Negative_regulation of Ren1 1 0.16 0.64 0.05 95.84
59 INT140332 RPL7AP5 Negative_regulation of Ltp 1 0.00 0.64 1.47 95.60
60 INT43647 Binding of Eef1a1 and Man2a2 1 0.16 0.23 0.7 95.36
61 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14 95.36
62 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12 95.36
63 INT117199 Rgs1 Regulation of Rgs19 1 0.02 0.16 0.56 95.04
64 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78 94.84
65 INT231796 Binding of Fcr and Sle1 1 0.01 1.62 0.33 94.76
66 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54 94.72
67 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83 94.68
68 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 94.56
69 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53 94.40
70 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46 94.32
71 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13 94.12
72 INT161412 Pag1 Positive_regulation of Gene_expression of Tens1 1 0.11 0.56 0.9 93.92
73 INT203101 Binding of Aes and Mtx1 2 0.25 0.24 0.88 93.68
74 INT313377 Trib3 Regulation of Gene_expression of Gfap 1 0.01 0.37 0.44 93.48
75 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44 93.48
76 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97 93.32
77 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51 92.96
78 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57 92.88
79 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 92.40
80 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2 92.40
81 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45 92.24
82 INT75200 Umod Positive_regulation of Transcription of Psma4 1 0.02 1.04 0.92 92.08
83 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57 91.96
84 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27 91.92
85 INT257988 PTGER2 Regulation of Gene_expression of PTGER1 1 0.15 0.4 0.05 91.84
86 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43 91.80
87 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43 91.80
88 INT39299 Binding of Prl and Dlst 1 0.20 0 0.27 91.52
89 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57 91.44
90 INT329473 SLC7A7 Regulation of Ca2 1 0.04 0.1 0.13 91.44
91 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27 91.20
92 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16 91.00
93 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17 90.68
94 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22 90.52
95 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23 90.48
96 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17 90.36
97 INT284587 Binding of Sele and Aecp 1 0.00 0.3 0.07 90.28
98 INT284586 Positive_regulation of Binding of Sele and Aecp 1 0.00 0.3 0.07 90.28
99 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75 90.24
100 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83 90.20
101 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16 90.20
102 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 90.08
103 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 90.08
104 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46 90.00
105 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83 89.92
106 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 89.84
107 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 89.84
108 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7 89.76
109 INT247271 Tlr4 Negative_regulation of SLC43A3 1 0.00 0.34 0.19 89.76
110 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57 89.68
111 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28 89.64
112 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83 89.48
113 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67 89.20
114 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24 89.04
115 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 89.04
116 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78 89.00
117 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41 88.56
118 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24 88.36
119 INT121843 HLA-DRB5 Negative_regulation of Accn4 1 0.00 0.54 0.73 88.24
120 INT51859 Pim1 Positive_regulation of Positive_regulation of Pdyn 1 0.02 0 0.31 88.08
121 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43 88.04
122 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43 88.04
123 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43 88.04
124 INT73381 Npy5r Positive_regulation of Positive_regulation of Npy 1 0.12 0 0.63 87.92
125 INT185270 Binding of Fgf2 and Ifaprc2 1 0.08 0.4 0.04 87.76
126 INT247270 Tlr4 Negative_regulation of Cebpz 1 0.04 0.33 0.19 87.68
127 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5 87.64
128 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57 87.52
129 INT79365 Pnoc Negative_regulation of Oprl1 2 0.41 0.16 1.72 87.52
130 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46 87.32
131 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19 87.28
132 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04 87.28
133 INT125389 Regulation of Flvcr2 Positive_regulation of Fbxo23 1 0.03 0.27 0.44 87.24
134 INT125388 Flvcr2 Positive_regulation of Fbxo23 1 0.05 0.27 0.42 87.24
135 INT136257 Tff3 Regulation of SGCG 1 0.00 0.18 1.24 87.12
136 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24 87.12
137 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23 87.12
138 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96 87.00
139 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95 87.00
140 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73 86.92
141 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91 86.88
142 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23 86.64
143 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23 86.40
144 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46 86.36
145 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46 86.36
146 INT40728 SST Regulation of IRG1 1 0.11 0.36 0.38 86.32
147 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43 86.24
148 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86 86.24
149 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86 86.24
150 INT249959 Cpa1 Regulation of NOS1 1 0.00 0.08 0.04 86.12
151 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13 86.04
152 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28 85.76
153 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67 85.68
154 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46 85.56
155 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46 85.56
156 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14 85.44
157 INT222527 Gal Regulation of Vip 1 0.03 0.05 0.22 85.44
158 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22 85.16
159 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7 84.96
160 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85 84.84
161 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 84.80
162 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87 84.68
163 INT273658 Dss1 Positive_regulation of Mpo 1 0.16 0.98 0.19 84.40
164 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77 84.24
165 INT162995 Positive_regulation of Binding of Ephb1 and Ppm1e 1 0.04 0.06 0.74 84.24
166 INT140892 Penk Negative_regulation of Mnp 1 0.13 0.55 1.75 84.20
167 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87 84.20
168 INT76769 Negative_regulation of Binding of HTR1E and Gs 1 0.00 0.44 0.72 84.12
169 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29 83.80
170 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95 83.52
171 INT119548 Fos Regulation of Gene_expression of Nfe2l2 1 0.48 0.47 0.25 83.52
172 INT76770 Binding of HTR1E and Gs 1 0.00 0.87 1.42 83.08
173 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25 83.00
174 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63 82.72
175 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09 82.08
176 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35 82.00
177 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6 81.68
178 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54 81.60
179 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5 81.56
180 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64 81.16
181 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29 81.16
182 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89 81.12
183 INT216040 Binding of Comt and Prodh 1 0.30 1.71 0.26 80.84
184 INT216039 Binding of Prodh and Zdhhc8 1 0.30 0.85 0.13 80.84
185 INT284857 S100a10 Positive_regulation of Gene_expression of Nav1 1 0.16 0.3 0.17 80.76
186 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 80.72
187 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08 80.52
188 INT220812 Tert Positive_regulation of Gene_expression of hl 1 0.01 0.14 0.04 80.48
189 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 0.41 0.14 0.04 80.48
190 INT220808 Tert Positive_regulation of Gene_expression of Krt31 1 0.43 0.14 0.04 80.48
191 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91 80.08
192 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 79.84
193 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54 79.80
194 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11 79.72
195 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54 79.52
196 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63 79.32
197 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74 79.32
198 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01 79.32
199 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01 79.32
200 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 79.28

Single Events

The table below shows the top 200 pain related interactions that have been reported for withdrawal. They are ordered first by their pain relevance and then by number of times they were reported in withdrawal. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
2 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 100.00
3 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
4 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
5 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
6 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
7 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
8 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 100.00
9 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
10 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
11 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
12 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
13 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
14 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
15 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 100.00
16 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 100.00
17 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17 100.00
18 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 100.00
19 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
20 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 100.00
21 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 100.00
22 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
23 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29 100.00
24 INT16714 Regulation of Creb1 64 0.62 22.23 33.56 100.00
25 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
26 INT17593 Regulation of Jun 37 0.60 5.5 14.35 100.00
27 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
28 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 100.00
29 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05 100.00
30 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
31 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 100.00
32 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 100.00
33 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
34 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93 100.00
35 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
36 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 100.00
37 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46 100.00
38 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 100.00
39 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 100.00
40 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04 100.00
41 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
42 INT81885 Regulation of Gene_expression of Naa15 5 0.40 1.56 4.59 100.00
43 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33 100.00
44 INT142793 Positive_regulation of Ccdc88a 7 0.41 0.93 5.98 100.00
45 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 100.00
46 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
47 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 100.00
48 INT5040 Regulation of Gal 42 0.60 12.72 21.18 100.00
49 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
50 INT11807 Gene_expression of Il2 266 0.78 112 64.97 100.00
51 INT164558 Binding of PERP 3 0.14 1.55 1.67 100.00
52 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 100.00
53 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 100.00
54 INT233010 Gene_expression of PERP 5 0.26 6.04 1.66 100.00
55 INT312933 Localization of Hes3 1 0.63 7.94 0.53 100.00
56 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93 100.00
57 INT281889 Localization of PERP 2 0.35 1.34 0.47 100.00
58 INT11275 Regulation of Fos 37 0.60 5.79 18.18 100.00
59 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82 100.00
60 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 100.00
61 INT169561 Negative_regulation of Dss1 8 0.28 4.92 1.01 100.00
62 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36 100.00
63 INT110866 Regulation of Gene_expression of Narp 2 0.41 3.2 1.28 100.00
64 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 100.00
65 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 100.00
66 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 100.00
67 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
68 INT12575 Regulation of Hpse 33 0.59 17.7 18.45 100.00
69 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26 100.00
70 INT97218 Regulation of Gene_expression of Grm8 3 0.24 2.26 2.97 100.00
71 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23 100.00
72 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71 100.00
73 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45 100.00
74 INT7801 Positive_regulation of Localization of Pag1 7 0.32 5.96 8.67 100.00
75 INT316075 Negative_regulation of Negative_regulation of Kitl 1 0.06 0.42 1.41 100.00
76 INT157067 Regulation of Regulation of Cpb2 2 0.22 1.29 1.39 100.00
77 INT281885 Negative_regulation of PERP 2 0.20 0.69 0.28 100.00
78 INT929 Positive_regulation of Oprl1 64 0.70 14.67 52.84 100.00
79 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19 100.00
80 INT20028 Positive_regulation of Gene_expression of Ghrh 9 0.50 1.52 2.62 100.00
81 INT118909 Positive_regulation of S100a10 1 0.32 0.95 2.81 100.00
82 INT5338 Regulation of Npy 92 0.62 25.54 51.24 100.00
83 INT8782 Regulation of Gpi 5 0.28 1.63 2.51 100.00
84 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 100.00
85 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65 100.00
86 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 100.00
87 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
88 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 100.00
89 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33 100.00
90 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26 100.00
91 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26 100.00
92 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
93 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 100.00
94 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47 100.00
95 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09 100.00
96 INT105837 Regulation of Gene_expression of Grk5 1 0.44 0.16 2.68 100.00
97 INT161158 Positive_regulation of Phosphorylation of Nts 1 0.30 0.18 0.85 100.00
98 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66 100.00
99 INT27694 Positive_regulation of Positive_regulation of ADRA1D 10 0.70 1.52 3.57 100.00
100 INT7974 Regulation of Gene_expression of PLOD1 6 0.42 0.41 1.99 100.00
101 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83 100.00
102 INT48367 Positive_regulation of Xpnpep3 6 0.11 1.76 4.76 100.00
103 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 100.00
104 INT80442 Positive_regulation of POLE3 2 0.31 0.64 1.93 100.00
105 INT61025 Negative_regulation of Negative_regulation of Il6 3 0.43 1.15 0.56 100.00
106 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 100.00
107 INT175278 Gene_expression of SLC10A4 1 0.15 0.32 0.3 100.00
108 INT175277 Negative_regulation of Gene_expression of SLC10A4 1 0.10 0.19 0.27 100.00
109 INT119401 Negative_regulation of Phosphorylation of Camk2n2 1 0.17 0.24 1.59 100.00
110 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64 100.00
111 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72 100.00
112 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06 100.00
113 INT273657 Negative_regulation of Negative_regulation of Dss1 2 0.13 0.91 0.29 100.00
114 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65 100.00
115 INT1617 Positive_regulation of Binding of Oprl1 10 0.59 0.63 9.79 100.00
116 INT24619 Regulation of Thop1 11 0.44 1.24 4.5 100.00
117 INT13742 Gene_expression of Son 45 0.58 2.98 4.19 100.00
118 INT142785 Positive_regulation of Positive_regulation of Ccdc88a 1 0.27 0.14 1.04 100.00
119 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 100.00
120 INT44316 Protein_catabolism of Dpa 2 0.16 0.15 1.37 100.00
121 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 100.00
122 INT53710 Regulation of Negative_regulation of Arhgdia 1 0.18 0 0.92 100.00
123 INT114200 Negative_regulation of Gene_expression of Slc6a1 1 0.38 0.41 1.18 100.00
124 INT23525 Regulation of FEM1B 5 0.44 1.26 1.22 100.00
125 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 100.00
126 INT265696 Negative_regulation of Transcription of Oxt 2 0.39 0.57 1.11 100.00
127 INT312930 Positive_regulation of Gene_expression of Hes3 1 0.54 0.22 0.12 100.00
128 INT347253 Positive_regulation of Localization of PERP 1 0.19 0.45 0.1 100.00
129 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67 100.00
130 INT1357 Positive_regulation of Pde11a 1 0.46 0 0.36 100.00
131 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 100.00
132 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 100.00
133 INT27459 Negative_regulation of Plbd2 2 0.06 0.08 1.38 100.00
134 INT5340 Negative_regulation of Positive_regulation of Npy 12 0.55 3.83 8.23 100.00
135 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72 100.00
136 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61 100.00
137 INT281886 Positive_regulation of PERP 1 0.22 0.29 0.08 100.00
138 INT158663 Negative_regulation of Gene_expression of Sgpl1 3 0.11 0.91 2.17 100.00
139 INT5476 Regulation of Gabbr1 21 0.45 4.01 10.26 100.00
140 INT10006 Regulation of Mtr 9 0.23 3.56 5.42 100.00
141 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 100.00
142 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 100.00
143 INT15166 Positive_regulation of Mme 40 0.70 13.01 16.24 100.00
144 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 100.00
145 INT191669 Localization of Igh-Dex 8 0.26 4.35 3.54 100.00
146 INT259086 Binding of Trpc1 3 0.22 1.27 1.37 100.00
147 INT259087 Negative_regulation of Binding of Trpc1 1 0.17 1.04 1.05 100.00
148 INT96482 Positive_regulation of Hal 1 0.36 0 0.9 100.00
149 INT44841 Positive_regulation of Regulation of Oxt 1 0.50 0 0.9 100.00
150 INT75549 Protein_catabolism of Ngf 3 0.88 1.59 0.88 100.00
151 INT129967 Binding of Cnot4 3 0.03 2.61 0.75 100.00
152 INT91274 Negative_regulation of Positive_regulation of Il2 2 0.42 1.12 0.74 100.00
153 INT251551 Negative_regulation of Gene_expression of Tnfrsf1b 1 0.30 0.85 0.32 100.00
154 INT254763 Localization of DNMT1 1 0.05 0.2 0.29 100.00
155 INT178487 Gene_expression of Cnot4 3 0.05 1.87 0.2 100.00
156 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.98
157 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 99.98
158 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.98
159 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.98
160 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.98
161 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 99.98
162 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 99.98
163 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29 99.98
164 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63 99.98
165 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.98
166 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7 99.98
167 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 99.98
168 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.98
169 INT65078 Negative_regulation of Pnoc 64 0.59 15.48 59.81 99.98
170 INT110862 Positive_regulation of Narp 10 0.40 2.8 7.13 99.98
171 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 99.98
172 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68 99.98
173 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 99.98
174 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 99.98
175 INT78033 Positive_regulation of Gene_expression of Oxtr 10 0.70 2.5 4.15 99.98
176 INT102508 Positive_regulation of Gene_expression of B3galt6 1 0.47 1.02 4.64 99.98
177 INT114181 Negative_regulation of Positive_regulation of Il12a 7 0.34 3.65 2.82 99.98
178 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08 99.98
179 INT7032 Positive_regulation of Pdyn 94 0.66 26.51 58.83 99.98
180 INT23738 Regulation of Transcription of Oprd1 6 0.26 0.48 4.3 99.98
181 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.98
182 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 99.98
183 INT6229 Positive_regulation of Gene_expression of Sult1b1 18 0.22 2.21 6.04 99.98
184 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38 99.98
185 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 99.98
186 INT84496 Regulation of Positive_regulation of Ephb1 18 0.61 10.16 13.92 99.98
187 INT135000 Positive_regulation of Gene_expression of GRM2 1 0.49 1.27 2.62 99.98
188 INT103456 Positive_regulation of SMPD2 4 0.49 1.85 0.55 99.98
189 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18 99.98
190 INT9932 Positive_regulation of Positive_regulation of Trh 13 0.50 1.8 7.63 99.98
191 INT164439 Positive_regulation of Nacc1 1 0.04 1.04 1.44 99.98
192 INT98527 Positive_regulation of Transcription of Chrne 1 0.03 0.36 1.62 99.98
193 INT52915 Positive_regulation of Positive_regulation of Prkca 4 0.64 0.31 5.21 99.98
194 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 99.98
195 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57 99.98
196 INT135001 Regulation of Gene_expression of GRM2 1 0.26 0.1 0.63 99.98
197 INT123827 Positive_regulation of Phosphorylation of Mapk3 10 0.67 5.22 3.82 99.98
198 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96 99.98
199 INT168597 Positive_regulation of Phosphorylation of Ndor1 1 0.41 0.3 1.32 99.98
200 INT168603 Negative_regulation of Positive_regulation of Mmp9 3 0.37 2.32 2.42 99.98
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