Y:1997

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 1997. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 1997. They are ordered first by their pain relevance and then by number of times they were reported in 1997. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 1997 Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 11 0.54 5.93 32.4
2 INT69872 Binding of MC1R and POMC 52 6 0.54 8.87 18.3
3 INT6078 Pomc Positive_regulation of Localization of Penk 13 4 0.51 0 15.49
4 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 3 0.64 2.12 14.2
5 INT69886 Ngf Positive_regulation of Calca 8 5 0.76 2.98 12.77
6 INT10161 Binding of Cck and Penk 6 3 0.53 0.97 11.15
7 INT68514 Pnoc Positive_regulation of Oprl1 10 4 0.59 3.56 9.57
8 INT6079 Pomc Positive_regulation of Penk 9 2 0.43 0 9.46
9 INT26468 Ghrh Positive_regulation of Localization of Gh 21 3 0.37 3.26 9.21
10 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 5 0.78 0.08 7.29
11 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 1 0.76 8.19 6.66
12 INT15842 Crh Positive_regulation of Localization of Pomc 15 1 0.73 5 5.05
13 INT69888 Ngf Positive_regulation of Localization of Calca 4 2 0.52 0.51 4.95
14 INT10844 Ghrh Regulation of Gh 13 3 0.13 4.77 4.71
15 INT64480 Binding of OPRL1 and PNOC 2 4 0.33 0.23 4.38
16 INT69032 IL18 Positive_regulation of IFNA1 12 4 0.23 7.87 3.83
17 INT11252 Cck Positive_regulation of Fos 6 2 0.78 0 3.79
18 INT69938 Cck Positive_regulation of Localization of Abat 2 1 0.29 0 3.78
19 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 2 0.03 0.13 3.64
20 INT29837 Gnrh1 Positive_regulation of LH 6 1 0.67 0 3.53
21 INT57985 Il1b Positive_regulation of Il6 5 1 0.59 1.66 3.53
22 INT69770 Penk Negative_regulation of Pscs 1 3 0.11 0.22 3.39
23 INT69823 Binding of GHR and RYBP 1 3 0.01 0 3.23
24 INT17456 Binding of CSF2 and POMC 3 3 0.32 4.06 3.15
25 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 1 0.31 0 3.14
26 INT28235 Binding of Cck and Gast 5 1 0.38 0.73 2.96
27 INT73821 CALCA Positive_regulation of Localization of IL8 1 4 0.25 2.37 2.91
28 INT69937 Cck Positive_regulation of Abat 2 1 0.31 0 2.88
29 INT69030 IL18 Positive_regulation of IL12A 3 2 0.31 5.57 2.72
30 INT67663 Ins1 Positive_regulation of Ntrk2 1 2 0.00 0.19 2.59
31 INT70757 Binding of Oprl1 and Pnoc 5 1 0.03 0.23 2.55
32 INT67905 Binding of Spn and Fosl1 1 2 0.24 2.1 2.54
33 INT69665 Binding of Oprd1 and Pnoc 5 1 0.35 0.4 2.5
34 INT69887 Ngf Regulation of Calca 2 1 0.49 0.1 2.19
35 INT49242 Binding of Mc1r and Pomc 10 1 0.38 3.79 2.15
36 INT66803 Oxt Regulation of Avp 7 4 0.16 0.19 2.15
37 INT70043 IL6 Regulation of IL10 3 1 0.18 3.59 2.01
38 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 2 0.57 0.18 2
39 INT69556 Slc7a11 Regulation of Cpe 2 1 0.06 0.46 1.95
40 INT68272 Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
41 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
42 INT51051 IL1B Positive_regulation of Localization of IL6 7 5 0.57 3.79 1.87
43 INT75069 Penk Regulation of Gene_expression of Pkhd1l1 1 2 0.09 0 1.85
44 INT72468 Negative_regulation of Binding of OPRL1 and PNOC 1 2 0.40 0 1.83
45 INT70225 oh Regulation of Oprd1 1 1 0.20 0.13 1.8
46 INT29715 Crh Negative_regulation of Localization of LH 5 1 0.43 0 1.78
47 INT34472 Penk Regulation of Slc3a1 2 1 0.03 0.42 1.74
48 INT31534 Binding of Sst and Oprl1 2 1 0.16 0.53 1.74
49 INT68709 Positive_regulation of Crh Regulation of Npr1 1 2 0.03 0 1.71
50 INT68710 Crh Regulation of Npr1 1 2 0.03 0 1.7
51 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 2 0.14 0 1.7
52 INT69666 Binding of OPRL1 and Pnoc 2 1 0.45 0.06 1.66
53 INT67966 Cck Positive_regulation of Adarb1 2 2 0.03 0 1.63
54 INT32482 Ghrh Positive_regulation of Prl 3 1 0.18 0.26 1.62
55 INT32412 Penk Regulation of Pomc 3 1 0.21 0.36 1.62
56 INT73016 PDYN Regulation of TAC1 1 1 0.29 0.34 1.54
57 INT69031 IL12A Positive_regulation of IFNA1 9 4 0.13 4.23 1.52
58 INT69709 NPL Positive_regulation of Localization of POMC 2 1 0.36 1.22 1.51
59 INT72666 Binding of ODT and Oprm1 1 1 0.03 0.53 1.5
60 INT69788 Binding of Gpr1 and Pnoc 2 2 0.09 0 1.49
61 INT72755 Tap1 Negative_regulation of TNF 1 2 0.43 2.45 1.46
62 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 1 0.10 0.1 1.44
63 INT69337 Oprm1 Positive_regulation of Atxn2l 1 1 0.01 0.27 1.43
64 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 2 0.12 0 1.41
65 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 2 0.20 0.19 1.4
66 INT52568 HTR1D Regulation of Localization of Gh 2 1 0.20 0.16 1.34
67 INT68071 Binding of Tic1 and Rbm39 1 3 0.01 2.54 1.33
68 INT71395 Ugt2a2 Regulation of Bcl2a1a 1 1 0.00 0.1 1.32
69 INT90221 Binding of CYP2D6 and Cyp1a2 1 1 0.03 0.09 1.31
70 INT73398 Binding of Pnoc and Nr1d2 1 2 0.10 0 1.27
71 INT71109 Binding of INSRR and MC1R 1 3 0.01 0 1.27
72 INT71989 Binding of Pdyn and Insrr 1 1 0.01 0 1.27
73 INT30744 Sst Regulation of Cck 1 1 0.28 0.43 1.27
74 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 1 0.01 0 1.27
75 INT70226 Binding of TAC1 and B3GAT1 4 1 0.24 4.5 1.26
76 INT70037 TNF Regulation of IL10 2 1 0.09 2.11 1.26
77 INT70181 PRCP Positive_regulation of FOS 1 4 0.58 0.36 1.26
78 INT69279 Regulation of Binding of TSPO and Gabrg1 1 2 0.00 2.05 1.26
79 INT67383 Binding of OPRK1 and Pdyn 2 1 0.00 0 1.25
80 INT71070 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Cck 1 1 0.26 0 1.24
81 INT70570 su Positive_regulation of Gh 1 2 0.01 0.15 1.24
82 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 1 0.01 0.19 1.24
83 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 1 0.58 0.81 1.23
84 INT70028 LTA Regulation of PRF1 1 1 0.02 1.42 1.21
85 INT70036 LTA Regulation of Negative_regulation of IL10 1 1 0.03 1.42 1.21
86 INT70046 IL12A Regulation of IL10 1 1 0.07 1.42 1.21
87 INT70035 TNF Regulation of Negative_regulation of PRF1 1 1 0.05 1.42 1.21
88 INT70039 IL1B Regulation of Negative_regulation of IL10 1 1 0.07 1.42 1.21
89 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 1 0.04 1.42 1.21
90 INT70032 TNF Regulation of PRF1 1 1 0.05 1.42 1.21
91 INT70042 LTA Regulation of Negative_regulation of PRF1 1 1 0.02 1.42 1.21
92 INT70040 TNF Regulation of Negative_regulation of IL10 1 1 0.09 1.42 1.21
93 INT70033 IL6 Regulation of PRF1 1 1 0.03 1.42 1.21
94 INT70038 IL1B Regulation of PRF1 1 1 0.05 1.42 1.21
95 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 1 0.05 1.42 1.21
96 INT70044 IL12A Regulation of PRF1 1 1 0.04 1.42 1.21
97 INT70030 IL1B Regulation of IL10 1 1 0.07 1.42 1.21
98 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 1 0.03 1.42 1.21
99 INT70041 LTA Regulation of IL10 1 1 0.03 1.42 1.21
100 INT70034 IL12A Regulation of Negative_regulation of IL10 1 1 0.07 1.42 1.21
101 INT70029 IL6 Regulation of Negative_regulation of IL10 1 1 0.05 1.42 1.21
102 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 1 0.02 0.3 1.19
103 INT70289 Atxn2l Positive_regulation of Racgap1 1 1 0.04 0.29 1.15
104 INT69824 Negative_regulation of Binding of GHR and RYBP 1 1 0.01 0 1.14
105 INT69504 Binding of Nos1 and Gatm 1 2 0.05 0 1.13
106 INT72754 Adamts7 Negative_regulation of TNF 1 1 0.28 1.64 1.13
107 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 1 0.22 0.26 1.12
108 INT69338 Binding of Oprd1 and Oprm1 1 1 0.24 0.26 1.11
109 INT70603 Penk Positive_regulation of Pdyn 1 1 0.13 0 1.11
110 INT74185 Cck Negative_regulation of Drd1a 1 1 0.30 0.1 1.1
111 INT70270 Binding of ADRA2B and Pnoc 2 1 0.02 0.15 1.08
112 INT70495 CALCA Positive_regulation of CALCB 2 1 0.40 0 1.08
113 INT69889 Ngf Regulation of Localization of Calca 1 1 0.49 0.1 1.08
114 INT71176 Binding of ICAM1 and ITGB2 4 1 0.21 4.93 1.07
115 INT69874 POMC Negative_regulation of TYRP1 1 2 0.13 0 1.07
116 INT69871 ASIP Negative_regulation of TYRP1 1 2 0.36 0 1.07
117 INT69340 Binding of Igh-6 and Ngf 2 1 0.06 1.04 1.06
118 INT57986 Il1b Regulation of Positive_regulation of Il6 2 1 0.39 0.23 1.05
119 INT52562 Lhb Positive_regulation of Prl 3 1 0.00 1.09 1.02
120 INT72794 Cea Positive_regulation of MUC16 1 2 0.43 2.78 1.01
121 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 1 0.48 0 1
122 INT71000 Positive_regulation of Adarb1 Positive_regulation of Odc1 1 1 0.01 0 1
123 INT70105 SCD Positive_regulation of Oprm1 1 1 0.01 0 1
124 INT71319 Binding of Penk and Fos 3 1 0.40 0.15 0.99
125 INT69307 Prkcq Negative_regulation of TH1L 1 1 0.00 0.98 0.98
126 INT69506 CA2 Positive_regulation of PRKCA 1 1 0.50 0.42 0.98
127 INT69767 Binding of Htr1a and Ptgdr 1 1 0.23 0 0.97
128 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 1 0.06 0.99 0.96
129 INT74184 Cck Regulation of Localization of Drd1a 1 1 0.32 0.06 0.95
130 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 1 0.21 0.98 0.95
131 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 1 0.29 0.97 0.94
132 INT70803 Ngf Regulation of Tac4 1 1 0.06 0.39 0.93
133 INT70802 Ngf Regulation of Ppt1 1 1 0.21 0.39 0.93
134 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 1 0.05 0.17 0.93
135 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 2 0.09 0.18 0.93
136 INT72463 NA Positive_regulation of Binding of OPRL1 and PNOC 1 1 0.04 0 0.91
137 INT68799 Cyp3a62 Negative_regulation of Cyp2d1 1 1 0.35 0 0.91
138 INT72464 Positive_regulation of Binding of OPRL1 and PNOC 1 1 0.34 0 0.91
139 INT69870 ASIP Negative_regulation of Binding of MC1R and POMC 1 2 0.37 0 0.9
140 INT71408 Binding of Rvm and Nts 2 1 0.27 1.21 0.87
141 INT73492 PTGER2 Positive_regulation of Gene_expression of IL4 1 2 0.08 1.11 0.87
142 INT72467 Regulation of Binding of OPRL1 and PNOC 1 1 0.18 0 0.86
143 INT70670 Scd1 Positive_regulation of Gene_expression of Penk 1 1 0.11 0.1 0.86
144 INT67909 Binding of Cck and Plxna3 Positive_regulation of Cck 1 1 0.04 0.54 0.84
145 INT69846 Gnrh1 Regulation of Gene_expression of ANTXRL 1 1 0.00 0.1 0.84
146 INT69424 Binding of Agt and Oprd1 1 1 0.14 0 0.84
147 INT67908 Binding of Cck and Plxna3 1 1 0.04 0.54 0.84
148 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 1 0.02 0.08 0.83
149 INT73462 PTPLA Regulation of Gene_expression of SART1 1 1 0.00 0.79 0.82
150 INT73032 Cck Negative_regulation of Localization of Oxt 1 1 0.44 0 0.82
151 INT70422 Binding of Htr1a and Adarb1 1 1 0.01 0.37 0.81
152 INT73775 Binding of GH1 and GHR 4 1 0.35 0.68 0.8
153 INT72418 Binding of Cnr1 and Cnr2 3 1 0.42 0.07 0.79
154 INT69225 Pnoc Negative_regulation of Car1 1 1 0.42 0 0.78
155 INT72017 Binding of Adora2a and Ptprg 2 1 0.07 0 0.77
156 INT70058 Binding of Pnoc and Insrr 1 1 0.01 0.09 0.77
157 INT73087 Adarb1 Positive_regulation of Fos 1 1 0.02 0 0.76
158 INT69692 Helt Regulation of Prkaca 1 1 0.00 0.33 0.76
159 INT73776 Regulation of Binding of GH1 and GHR 2 1 0.26 0.16 0.75
160 INT72229 Binding of NFKBIL1 and BTRC 1 3 0.00 0 0.73
161 INT11684 Binding of CSF2 and IL3 6 4 0.36 3.3 0.72
162 INT72318 Adarb1 Positive_regulation of Positive_regulation of Cck 1 1 0.04 0 0.72
163 INT70011 Binding of Hrh1 and Insrr 1 2 0.00 0.4 0.72
164 INT72689 Binding of Oprd1 and Ptprg 1 1 0.00 0.38 0.71
165 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 1 0.04 0.56 0.71
166 INT68211 Binding of Calca and Chat 1 1 0.37 0 0.71
167 INT73824 TFF2 Positive_regulation of Localization of IL1B 1 1 0.02 0.56 0.71
168 INT67887 SCN5A Negative_regulation of INA 1 1 0.02 0.13 0.71
169 INT70568 su Negative_regulation of Ghrh Regulation of Gh 1 1 0.01 0.07 0.7
170 INT67809 Ugt2b1 Negative_regulation of Ugt2b7 1 1 0.47 0 0.7
171 INT71815 Coq10a Regulation of Oprd1 1 1 0.00 0.15 0.7
172 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 1 0.04 0.59 0.69
173 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 2 0.04 0 0.69
174 INT71988 Drd1a Regulation of Npr1 1 1 0.10 0 0.68
175 INT68561 Binding of Gli3 and Ust 1 1 0.01 0.68 0.68
176 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 1 0.23 1.82 0.67
177 INT70998 IL1B Regulation of Gene_expression of Icam1 1 2 0.44 0.95 0.67
178 INT70819 Binding of GBE1 and CTRC 1 1 0.01 0.63 0.67
179 INT69206 Ntf3 Negative_regulation of Ntf3 Positive_regulation of Penk 1 1 0.05 0.06 0.66
180 INT69205 Ntf3 Positive_regulation of Penk 1 1 0.06 0.06 0.66
181 INT70833 Binding of PDYN and Pnoc 1 1 0.53 0 0.65
182 INT70161 Casp1 Regulation of Oprd1 1 1 0.03 0 0.65
183 INT72146 POMC Positive_regulation of Phosphorylation of MYOT 1 1 0.00 0.25 0.65
184 INT70162 Casp1 Regulation of Penk 1 1 0.03 0 0.64
185 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 1 0.00 1.03 0.63
186 INT69226 Regulation of Pnoc Positive_regulation of Oprl1 1 1 0.19 0 0.63
187 INT71526 Regulation of Il1b Positive_regulation of Il6 1 1 0.17 0.14 0.62
188 INT69278 Binding of TSPO and Gabrg1 1 1 0.00 1.01 0.62
189 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 1 0.00 0.07 0.62
190 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 1 0.00 0.15 0.62
191 INT73402 Binding of Oprl1 and Wdyhv1 1 1 0.00 0 0.61
192 INT71944 PTGS2 Negative_regulation of VN1R106P 1 1 0.00 0.07 0.61
193 INT73403 Binding of Pdyn and Oprl1 1 1 0.01 0 0.61
194 INT71525 Oprd1 Regulation of Il6 1 1 0.16 0.19 0.6
195 INT70811 Penk Negative_regulation of Binding of Tyr and 1 1 0.01 0 0.6
196 INT70254 Binding of Htr1a and Ca2 1 1 0.31 0.5 0.6
197 INT75040 Binding of GHSR and MC1R 1 2 0.02 0.34 0.6
198 INT74656 YY1 Positive_regulation of Localization of IL2 1 1 0.07 0.09 0.58
199 INT72416 Binding of PDYN and El2 1 1 0.45 0 0.58
200 INT71110 Binding of MC1R and NDP 1 1 0.10 0 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported in 1997. They are ordered first by their pain relevance and then by number of times they were reported in 1997. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 1997 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 186 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 56 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 106 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 59 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 31 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 22 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 33 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 49 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 80 1163 0.70 319.28 684
10 INT292 Localization of Penk 23 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 1 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 40 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 19 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 33 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 63 934 0.70 209.8 503.87
16 INT155 Positive_regulation of Prl 26 1233 0.70 317.93 457.82
17 INT1045 Localization of LH 26 1211 0.81 87.04 456.25
18 INT443 Localization of POMC 38 1020 0.81 284.52 443.17
19 INT50058 Negative_regulation of Cpox 16 907 0.58 426.28 428.29
20 INT9238 Gene_expression of IL6 30 1575 0.78 1135.66 424.22
21 INT4758 Positive_regulation of Localization of Calca 8 557 0.70 138.55 411.04
22 INT5895 Gene_expression of Oprm1 13 525 0.78 120.67 407.29
23 INT64202 Positive_regulation of Trpv1 1 643 0.70 249.66 397.42
24 INT467 Gene_expression of POMC 34 1048 0.78 332.8 394.16
25 INT1395 Negative_regulation of Penk 23 537 0.59 87.33 389.81
26 INT6056 Negative_regulation of Gene_expression of Fos 36 601 0.59 193.05 386.84
27 INT2540 Negative_regulation of Calca 24 538 0.59 172.11 384.38
28 INT6580 Negative_regulation of Ptgs1 27 929 0.59 381.53 376.26
29 INT157 Positive_regulation of Localization of Prl 29 790 0.70 104.54 374.78
30 INT287 Localization of Cck 27 518 0.81 86.84 364.04
31 INT439 Localization of Gnrh1 35 976 0.81 100.96 363.25
32 INT720 Positive_regulation of POMC 16 807 0.70 237.37 353.83
33 INT5660 Binding of Oprd1 24 477 0.48 71.86 342.06
34 INT876 Localization of Gh1 17 843 0.80 67.75 340.82
35 INT16260 Gene_expression of Bdnf 7 671 0.78 283.44 339.1
36 INT5235 Negative_regulation of TNF 4 924 0.59 772.91 331.98
37 INT2649 Regulation of Calca 23 433 0.62 146.05 330.95
38 INT5059 Positive_regulation of TNF 4 1050 0.70 896.51 322.81
39 INT162 Regulation of Prl 27 794 0.62 165.01 322.24
40 INT5979 Gene_expression of Oprd1 23 428 0.78 75.64 320.32
41 INT34869 Negative_regulation of PTGS2 41 778 0.59 366.76 319.85
42 INT5540 Positive_regulation of Oprm1 14 344 0.70 76.77 319.71
43 INT5680 Gene_expression of Ngf 17 530 0.78 264.29 310.56
44 INT4941 Positive_regulation of Oprd1 12 345 0.70 74.26 304.41
45 INT9131 Positive_regulation of Prkcg 5 431 0.70 130.8 302.41
46 INT477 Localization of Avp 34 813 0.81 131.58 300.4
47 INT161 Regulation of Localization of Prl 21 615 0.62 65.37 298.66
48 INT1352 Localization of Acot1 41 728 0.80 73.01 296.01
49 INT886 Gene_expression of Pomc 24 676 0.78 129.87 295.98
50 INT11624 Gene_expression of OPRM1 10 445 0.78 72.36 294.36
51 INT5379 Gene_expression of Fos 2 656 0.78 255.5 292.54
52 INT3579 Localization of Oxt 14 555 0.81 43.35 292.44
53 INT9158 Gene_expression of Tnf 23 722 0.78 522.01 277.68
54 INT2365 Positive_regulation of Cck 35 354 0.70 87.8 277.41
55 INT49750 Negative_regulation of CPOX 10 735 0.58 360.06 274.19
56 INT6852 Localization of TNF 5 883 0.81 705.95 270.84
57 INT10832 Gene_expression of IL8 5 1050 0.78 698.72 270
58 INT1396 Binding of Penk 5 355 0.48 22.79 269.65
59 INT5591 Regulation of Gene_expression of Fos 32 425 0.62 129.06 265.78
60 INT9659 Gene_expression of Il6 13 991 0.78 715.11 265.57
61 INT5972 Gene_expression of IL1B 23 948 0.78 510.91 263.97
62 INT68684 Gene_expression of VEGFA 7 2371 0.78 1742.52 259.2
63 INT1893 Localization of Gh 61 1041 0.79 340.23 256.58
64 INT16868 Gene_expression of Il6 19 807 0.78 499.48 256.57
65 INT2909 Positive_regulation of Abat 16 334 0.70 62.1 256.43
66 INT3948 Regulation of Cck 16 291 0.62 58.07 255.88
67 INT5501 Regulation of Oprd1 21 283 0.62 55.1 249.9
68 INT1005 Localization of Sst 3 385 0.81 26.31 244.56
69 INT738 Regulation of POMC 12 459 0.62 111.19 243.74
70 INT1902 Gene_expression of Cck 26 348 0.78 70.33 241.92
71 INT11377 Positive_regulation of Ngf 12 331 0.70 206.5 238
72 INT1562 Localization of Crh 9 499 0.81 126.74 236.68
73 INT5597 Gene_expression of Pdyn 31 433 0.78 62.97 235.47
74 INT1665 Positive_regulation of Pag1 4 270 0.68 186.63 229.87
75 INT4759 Negative_regulation of Localization of Calca 6 294 0.59 82.62 226.45
76 INT9987 Gene_expression of Abat 6 296 0.78 95.46 226.34
77 INT6406 Binding of Oprm1 16 280 0.48 40.54 226.26
78 INT1212 Binding of Oprl1 12 312 0.48 28.6 225.15
79 INT11009 Phosphorylation of Creb1 9 458 0.82 111.34 221.97
80 INT626 Localization of CALCA 5 289 0.81 125.39 221.15
81 INT6665 Gene_expression of FOS 27 520 0.77 165.31 217.66
82 INT1308 Localization of Pomc 5 457 0.81 66.83 217.5
83 INT6293 Gene_expression of Oprm1 21 312 0.78 48.73 215.61
84 INT767 Localization of Gnrhr 10 565 0.80 106.68 214.57
85 INT4893 Gene_expression of Tacr1 1 366 0.78 129.67 213.92
86 INT22548 Positive_regulation of Casp3 4 483 0.70 258.78 213.07
87 INT6482 Positive_regulation of Gene_expression of TNF 13 659 0.70 569.88 210
88 INT16259 Positive_regulation of Bdnf 2 336 0.70 183.48 209.82
89 INT48955 Gene_expression of Nos2 7 753 0.78 403.87 208.08
90 INT2651 Positive_regulation of Pomc 12 403 0.70 95.72 206.24
91 INT2391 Negative_regulation of PTGS1 26 501 0.59 207.62 205.6
92 INT798 Positive_regulation of Gene_expression of Penk 26 394 0.70 78.53 203.07
93 INT11313 Positive_regulation of Il6 18 526 0.70 331.27 201.59
94 INT2211 Negative_regulation of Abat 5 267 0.59 66.51 200.98
95 INT50670 Gene_expression of CPOX 7 763 0.76 442.13 195.02
96 INT156 Negative_regulation of Prl 14 542 0.59 131.97 192.24
97 INT528 Gene_expression of Prl 13 693 0.78 217.18 192.2
98 INT6488 Gene_expression of Tnf 25 484 0.78 339.61 191.58
99 INT2085 Positive_regulation of LH 13 441 0.70 60.15 191.02
100 INT6354 Localization of Gabrg1 12 321 0.74 41.41 186.74
101 INT1652 Regulation of Pomc 8 387 0.62 61.01 186.51
102 INT24326 Gene_expression of Ngf 4 346 0.78 218.67 184.71
103 INT10194 Positive_regulation of IL6 9 702 0.70 600.62 183.38
104 INT4803 Transcription of Penk 23 435 0.72 59.09 182.4
105 INT3440 Negative_regulation of Localization of Abat 8 221 0.57 33.94 180.36
106 INT12602 Negative_regulation of Oprm1 7 190 0.59 36.11 177.85
107 INT49441 Negative_regulation of Cpox 4 494 0.59 303.22 177.46
108 INT7506 Negative_regulation of Ltp 4 267 0.46 91.01 176.8
109 INT1429 Gene_expression of PDYN 10 308 0.78 61.33 175.65
110 INT19472 Gene_expression of Il1 3 554 0.76 419.75 175.35
111 INT943 Negative_regulation of Cck 15 205 0.59 38.42 174.78
112 INT26472 Regulation of Oprm1 12 191 0.62 35.84 173.1
113 INT15516 Gene_expression of Crp 6 711 0.77 615.33 173.09
114 INT5930 Positive_regulation of Oprm1 20 221 0.70 31.19 172.93
115 INT159 Negative_regulation of Localization of Prl 8 416 0.59 55.34 171.8
116 INT4937 Negative_regulation of Oprd1 9 224 0.59 44.51 171.11
117 INT438 Gene_expression of Crh 6 376 0.78 159.11 169.17
118 INT867 Gene_expression of IFNA1 9 930 0.78 594.85 168.03
119 INT739 Negative_regulation of POMC 8 358 0.59 102.28 166.77
120 INT1114 Localization of Ins1 2 748 0.80 192.95 165.48
121 INT4768 Positive_regulation of OPRM1 5 212 0.70 31.09 164.28
122 INT2366 Binding of Cck 13 192 0.48 30.64 163.46
123 INT5127 Localization of Lhb 9 488 0.80 50.48 162.66
124 INT3448 Positive_regulation of Gh 33 521 0.69 180.03 161.18
125 INT5513 Negative_regulation of Pomc 1 295 0.59 60.9 158.63
126 INT51921 Gene_expression of Cpox 8 501 0.73 229.81 157.81
127 INT21185 Binding of Ptprg 35 213 0.47 13.49 157.75
128 INT768 Positive_regulation of Oprl1 11 179 0.70 40.05 156.93
129 INT1303 Negative_regulation of Npr1 14 278 0.55 35.1 156.78
130 INT2640 Gene_expression of Pomc 7 424 0.78 120.72 155.37
131 INT6042 Binding of Oprm1 10 248 0.48 31.77 154.34
132 INT4740 Gene_expression of Th 4 298 0.78 61.27 154.03
133 INT2910 Regulation of Abat 8 169 0.62 36.95 153.53
134 INT1044 Negative_regulation of Localization of LH 12 358 0.59 25.95 151.31
135 INT4829 Positive_regulation of Localization of Abat 15 199 0.55 20.91 150.48
136 INT880 Positive_regulation of Localization of Gh1 2 304 0.70 14.79 150.23
137 INT15515 Positive_regulation of Crp 6 700 0.70 604.24 150.15
138 INT5050 Regulation of Localization of Calca 3 149 0.62 41.25 148.57
139 INT6108 Gene_expression of Npy 12 292 0.78 110.65 148.21
140 INT13353 Positive_regulation of Tnf 9 332 0.70 248.75 148.1
141 INT7628 Gene_expression of Ltp 4 273 0.77 70.21 147.87
142 INT2451 Positive_regulation of Avp 11 355 0.70 102.66 147.69
143 INT1033 Positive_regulation of Ca2 4 507 0.68 131.76 147.64
144 INT9852 Positive_regulation of Gpt 8 563 0.70 364.64 146.82
145 INT5116 Gene_expression of IL2 22 670 0.78 291.13 146.69
146 INT812 Localization of INS 8 1026 0.81 515.6 145.31
147 INT425 Localization of PRL 5 455 0.81 189.64 144.8
148 INT2379 Positive_regulation of Localization of LH 12 349 0.70 27.86 144.53
149 INT3300 Positive_regulation of Gene_expression of Calca 2 179 0.70 77.76 144.2
150 INT2780 Regulation of Gene_expression of Penk 14 265 0.62 32.45 143.88
151 INT60694 Gene_expression of Il10 8 567 0.78 369.48 143.69
152 INT1414 Regulation of Oprl1 16 169 0.62 32.05 139.99
153 INT1273 Gene_expression of Avp 7 356 0.78 90.56 138.7
154 INT48895 Gene_expression of Il10 3 333 0.78 221.2 138.52
155 INT2867 Gene_expression of CALCA 10 247 0.78 78.78 138.47
156 INT5061 Negative_regulation of Mme 9 306 0.59 51.97 136.9
157 INT4658 Binding of OPRM1 2 188 0.48 25.96 136.24
158 INT1047 Negative_regulation of LH 17 314 0.59 53.71 135.89
159 INT2541 Binding of Calca 2 200 0.48 67.14 134.62
160 INT11012 Positive_regulation of Creb1 1 258 0.70 84.4 132
161 INT48953 Positive_regulation of Nos2 18 486 0.70 239.85 131.87
162 INT5497 Positive_regulation of Crh 9 299 0.70 125.54 131.14
163 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
164 INT49439 Gene_expression of Cpox 2 508 0.73 326.97 130.17
165 INT5595 Positive_regulation of Pdyn 14 223 0.70 48.37 130.14
166 INT1614 Gene_expression of Oprl1 15 164 0.78 31.43 127.74
167 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
168 INT1878 Binding of HLA-B 11 440 0.48 321.16 127.36
169 INT695 Binding of POMC 11 304 0.48 56.66 126.85
170 INT65054 Positive_regulation of Nfkb1 5 285 0.70 149.33 126.73
171 INT5931 Regulation of Oprm1 11 149 0.62 18.15 125.93
172 INT6822 Gene_expression of Pdyn 9 215 0.78 35.99 125.76
173 INT416 Regulation of LH 6 253 0.62 31.48 125.55
174 INT5008 Localization of Calca 1 204 0.81 80.35 125.16
175 INT6323 Positive_regulation of Gabrg1 5 213 0.70 45.08 124.34
176 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
177 INT4259 Positive_regulation of Npr1 9 262 0.70 49.37 123.11
178 INT2106 Regulation of Localization of LH 7 279 0.62 22.37 122.77
179 INT252 Localization of GH1 13 529 0.80 227.4 122.05
180 INT6128 Positive_regulation of Localization of POMC 12 256 0.70 68.77 121.64
181 INT218 Positive_regulation of Th 5 245 0.70 40.5 120.1
182 INT2555 Positive_regulation of Localization of Penk 1 116 0.70 24.35 119.73
183 INT8243 Positive_regulation of Il6 1 451 0.70 358.24 119.28
184 INT1026 Binding of Lbp 1 207 0.48 150.96 119.16
185 INT12501 Positive_regulation of Adarb1 10 166 0.58 36.94 118.92
186 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
187 INT9235 Negative_regulation of Gene_expression of TNF 4 346 0.59 252.98 118.61
188 INT50674 Gene_expression of PTGS2 23 459 0.78 253.33 118.51
189 INT7395 Localization of GNRH1 15 399 0.81 62.88 117.68
190 INT12339 Localization of IL8 3 437 0.81 251.87 117.39
191 INT1438 Localization of Pomc 7 360 0.81 101.26 116.47
192 INT4207 Regulation of Avp 15 267 0.62 63.72 115.33
193 INT62124 Gene_expression of NOS1 5 444 0.78 218.08 114.85
194 INT48593 Positive_regulation of NOS1 3 420 0.68 226.15 114.71
195 INT1793 Localization of CGA 4 379 0.81 67.38 114.69
196 INT20374 Gene_expression of Il4 2 515 0.76 306.15 114.12
197 INT16253 Positive_regulation of Gene_expression of Bdnf 4 196 0.70 92.67 113.01
198 INT90 Localization of Gast 20 400 0.81 137.67 113
199 INT1530 Regulation of Gh 30 382 0.61 115.96 112.47
200 INT11011 Positive_regulation of Phosphorylation of Creb1 4 190 0.70 49.25 112.01
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