Y:1998

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 1998. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 1998. They are ordered first by their pain relevance and then by number of times they were reported in 1998. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 1998 Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 4 0.54 5.93 32.4
2 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 1 0.64 2.12 14.2
3 INT68514 Pnoc Positive_regulation of Oprl1 10 3 0.59 3.56 9.57
4 INT77646 Binding of Ngf and Ntrk1 23 2 0.40 7.85 9.26
5 INT65724 Binding of Pnoc and Oprl1 8 1 0.33 2.94 8.82
6 INT79759 Ngf Regulation of Il6 1 4 0.60 4.62 5.62
7 INT20133 Trh Positive_regulation of Localization of Prl 23 1 0.78 2.04 5.44
8 INT1392 Trh Regulation of Prl 15 1 0.29 2.47 4.29
9 INT40114 Binding of OPRD1 and Oprm1 2 2 0.00 0 4.29
10 INT11613 Cck Positive_regulation of Localization of Oxt 3 2 0.53 0 4.17
11 INT73539 Binding of Ngf and Ngfr 5 1 0.45 3.99 4
12 INT61359 TNF Positive_regulation of NFKB1 11 1 0.63 6.66 3.89
13 INT17317 Binding of Jun and Fos 7 1 0.42 1.03 3.5
14 INT73071 Binding of Cpe and Insrr 3 2 0.01 0.33 3.38
15 INT17300 Prss12 Positive_regulation of Localization of Acot1 4 2 0.11 0 3.28
16 INT74159 Ngf Regulation of Gene_expression of Calca 2 1 0.60 1.66 3.22
17 INT13729 GHRH Positive_regulation of Localization of GH1 13 1 0.62 0.59 3.2
18 INT70757 Binding of Oprl1 and Pnoc 5 1 0.03 0.23 2.55
19 INT74840 Binding of Cacna1a and Cacna1a 5 1 0.00 4.24 2.36
20 INT54489 Binding of Jun and Rabep2 4 3 0.16 1.48 2.3
21 INT76776 Binding of Pnoc and Ptprg 2 1 0.02 0 2.29
22 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 3 0.33 0.53 2.1
23 INT17299 Prss12 Regulation of Localization of Acot1 3 2 0.05 0 2.07
24 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 1 0.57 0.18 2
25 INT13430 Abat Positive_regulation of Localization of Sst 2 1 0.33 0 1.94
26 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 2 0.00 0 1.94
27 INT79365 Pnoc Negative_regulation of Oprl1 2 1 0.41 0.16 1.72
28 INT69666 Binding of OPRL1 and Pnoc 2 1 0.45 0.06 1.66
29 INT73116 TYMS Negative_regulation of DNMT3B 1 1 0.24 0 1.6
30 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 1 0.24 0 1.6
31 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 2 0.08 0 1.56
32 INT74937 IL1B Positive_regulation of CPOX 5 2 0.18 1.13 1.55
33 INT74843 Binding of Cacna1a and Ea2 3 1 0.13 3.29 1.55
34 INT69709 NPL Positive_regulation of Localization of POMC 2 1 0.36 1.22 1.51
35 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 2 0.03 0 1.51
36 INT79021 Regulation of Binding of Jun and Fos 2 1 0.50 0.66 1.5
37 INT73650 Binding of Pim3 and Creb1 1 5 0.03 2.48 1.47
38 INT10548 Nts Regulation of Localization of Abat 2 1 0.14 0 1.42
39 INT76770 Binding of HTR1E and Gs 1 2 0.00 0.87 1.42
40 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 1 0.00 0.56 1.41
41 INT78974 Binding of Prkcg and Prkaca 2 1 0.31 0.35 1.4
42 INT75371 Binding of Hrh1 and RGD735065 1 1 0.00 0.55 1.4
43 INT73377 Npy Regulation of Adarb1 2 2 0.03 0.15 1.38
44 INT55837 Binding of HLA-B and PHB2 3 1 0.20 3.52 1.37
45 INT75807 Gpm6a Positive_regulation of Localization of Penk 1 1 0.04 0 1.35
46 INT76508 Pnoc Regulation of Oprl1 1 1 0.47 0.25 1.32
47 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 1 0.06 0.69 1.28
48 INT74841 Binding of Cacna1a and Ea2 2 1 0.01 2.33 1.27
49 INT73598 BAX Positive_regulation of Casp1 1 1 0.06 0.63 1.27
50 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 2 0.02 0 1.26
51 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 4 0.03 0.76 1.25
52 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 4 0.37 0 1.25
53 INT66205 TNF Positive_regulation of TNF Positive_regulation of NFKB1 4 1 0.41 2.74 1.24
54 INT20530 Nts Regulation of Prss12 5 1 0.24 0.74 1.23
55 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 1 0.00 0.08 1.22
56 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 1 0.44 0 1.22
57 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 1 0.02 0.08 1.22
58 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 2 0.29 1.24 1.22
59 INT75483 Binding of SGCG and TGFB1 1 3 0.52 2.27 1.19
60 INT75126 Pnoc Regulation of Localization of Avp 2 1 0.26 0.24 1.18
61 INT73075 Adarb1 Regulation of Fos 1 1 0.01 0.07 1.18
62 INT76256 Binding of Slc6a3 and Sigmar1 1 2 0.20 0 1.16
63 INT25026 PLOD1 Regulation of FSHR 4 1 0.19 0.38 1.15
64 INT76378 Binding of Cit and Flvcr2 1 2 0.09 0.17 1.15
65 INT76199 CASP1 Positive_regulation of CEL 1 2 0.06 0.32 1.14
66 INT39040 LH Positive_regulation of Localization of Gnrh1 3 1 0.51 0.41 1.12
67 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 2 0.05 0 1.12
68 INT25036 TRH Regulation of Prl 4 1 0.27 1.75 1.09
69 INT75806 Cyp2a5 Negative_regulation of Cyp2g1 1 1 0.48 0.08 1.09
70 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 3 0.58 0.72 1.09
71 INT70270 Binding of ADRA2B and Pnoc 2 1 0.02 0.15 1.08
72 INT76396 Il10 Negative_regulation of Il1b 2 1 0.65 1.89 1.08
73 INT172757 Rnpep Positive_regulation of Hps4 1 1 0.00 0 1.08
74 INT74460 GTS Negative_regulation of Casp3 1 1 0.04 0.37 1.08
75 INT17414 TRH Positive_regulation of Prl 4 1 0.47 0 1.07
76 INT77737 Pnoc Positive_regulation of Localization of Prl 3 1 0.55 0 1.07
77 INT79372 Calca Regulation of Pnoc 1 1 0.34 0 1.07
78 INT77982 Binding of YY1 and Oprm1 2 1 0.17 0.17 1.06
79 INT77083 Das Negative_regulation of Cyp2e1 1 1 0.20 0.59 1.06
80 INT73311 Binding of Oprm1 and Pdpn 1 3 0.08 0.71 1.06
81 INT76001 Ngf Positive_regulation of Ngfr 1 2 0.16 0.93 1.05
82 INT75247 Abat Regulation of Gene_expression of Tacr1 1 1 0.23 0.41 1.03
83 INT95378 Binding of Jun and Jund 5 4 0.20 2.06 1.02
84 INT74027 Creb1 Regulation of Jun 4 1 0.27 1.04 1.02
85 INT52562 Lhb Positive_regulation of Prl 3 1 0.00 1.09 1.02
86 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 1 0.01 0.52 1.02
87 INT75486 Binding of Tgfbr1 and Tgfbr2 1 2 0.10 1.94 1.02
88 INT74933 IRF6 Positive_regulation of Nfkb1 1 1 0.02 0.52 1.01
89 INT32327 POMC Positive_regulation of Localization of PRL 4 1 0.45 0 0.99
90 INT35157 GH1 Regulation of GHRH 3 1 0.17 0.5 0.99
91 INT71319 Binding of Penk and Fos 3 1 0.40 0.15 0.99
92 INT76150 Das Negative_regulation of Gpi1 1 1 0.03 0 0.99
93 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 1 0.30 0.38 0.99
94 INT73680 KNG1 Positive_regulation of ALB 1 1 0.51 0.38 0.98
95 INT78171 Pigm Regulation of Penk 1 2 0.02 1.04 0.97
96 INT75283 SST Negative_regulation of Localization of INS 2 1 0.47 1.45 0.96
97 INT77142 Binding of IFNG and IL4 2 1 0.03 1.16 0.95
98 INT77859 EDN1 Positive_regulation of MC1R 2 1 0.64 0.34 0.94
99 INT78976 Prkcg Regulation of Ina 1 2 0.13 0.16 0.93
100 INT75200 Umod Positive_regulation of Transcription of Psma4 1 1 0.02 1.04 0.92
101 INT72917 Binding of Crh and Crhr1 4 1 0.32 0.73 0.91
102 INT79123 Binding of Pnoc and Oprm1 3 2 0.14 0 0.91
103 INT77330 Oprk1 Regulation of Localization of GRIN1 1 1 0.24 0 0.91
104 INT78062 Il1a Positive_regulation of Localization of Il6 3 2 0.24 0.48 0.9
105 INT77253 Binding of gr and Creb1 1 1 0.03 0.4 0.9
106 INT77254 Binding of gr and Sp1 1 1 0.04 0.4 0.9
107 INT76062 Gnrhr Positive_regulation of Localization of LH 1 4 0.10 0 0.9
108 INT78449 Abat Positive_regulation of Localization of Vip 1 1 0.23 0 0.89
109 INT75920 Slc8a1 Negative_regulation of Cpox 1 2 0.03 0.85 0.89
110 INT74872 Igh-Dex Positive_regulation of Chd7 1 1 0.01 0.5 0.89
111 INT73653 Binding of Creb1 and Fos 1 3 0.40 1.49 0.87
112 INT76652 Cpe Positive_regulation of Il6 1 1 0.08 0 0.87
113 INT73538 Ngf Positive_regulation of Ngfr 2 1 0.41 1.05 0.85
114 INT65011 IL1B Positive_regulation of PTGER2 4 1 0.08 0.92 0.82
115 INT74383 Sst Positive_regulation of GEM 1 1 0.01 0.09 0.82
116 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 1 0.00 0.09 0.82
117 INT78972 Prkaca Regulation of Ina 1 2 0.11 0.09 0.82
118 INT77393 Binding of ARRB1 and OPRM1 1 1 0.15 0 0.82
119 INT74384 Regulation of Sst Positive_regulation of GEM 1 1 0.00 0.09 0.82
120 INT78348 Binding of GALR1 and GAL 4 1 0.41 1.47 0.8
121 INT78714 Ntrk1 Positive_regulation of Ngf 2 1 0.50 0.63 0.78
122 INT21543 Binding of Oprd1 and Cish 2 1 0.09 0.15 0.78
123 INT77526 Oprd1 Regulation of Positive_regulation of Odc1 1 2 0.01 0.12 0.78
124 INT76498 Binding of Tacr1 and Adora2a 1 1 0.09 0 0.77
125 INT74829 Oprd1 Regulation of Slc1a2 1 1 0.17 0 0.76
126 INT76499 Binding of Insr and Adora2a 1 1 0.08 0 0.76
127 INT28620 Penk Regulation of Crh 2 1 0.40 0.25 0.75
128 INT74252 Binding of Penk and Set 1 1 0.03 0 0.75
129 INT75399 Regulation of Binding of Dll1 and Oprd1 1 1 0.08 0 0.74
130 INT75937 MLXIPL Regulation of Csf2 1 1 0.01 0.68 0.74
131 INT75398 Binding of Dll1 and Oprd1 1 1 0.11 0 0.74
132 INT13344 Binding of Npy and Adarb1 2 1 0.02 0.41 0.73
133 INT76069 Binding of Oprl1 and Oprm1 1 1 0.07 0 0.73
134 INT76769 Negative_regulation of Binding of HTR1E and Gs 1 1 0.00 0.44 0.72
135 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 2 0.08 0.48 0.72
136 INT73838 IGHD4-4 Positive_regulation of CDC42BPG 1 2 0.00 0 0.71
137 INT77689 Binding of Ace and Tenc1 1 2 0.28 0.65 0.7
138 INT75405 Pdyn Positive_regulation of Localization of Pomc 1 1 0.06 0 0.7
139 INT74727 Binding of Slc6a4 and Hpic1 1 2 0.00 0.49 0.68
140 INT76655 POMC Positive_regulation of Transcription of Il6 1 1 0.01 0 0.68
141 INT76654 Cpe Positive_regulation of Transcription of Il6 1 1 0.05 0 0.68
142 INT74728 Binding of Slc6a4 and Ptprj 1 2 0.01 0.48 0.68
143 INT74599 YY1 Negative_regulation of ADCY1 2 1 0.36 0.31 0.67
144 INT74468 Adcyap1 Positive_regulation of Localization of Gnrhr 1 2 0.27 0 0.67
145 INT75936 Csf2 Positive_regulation of Oprk1 1 1 0.25 0.78 0.67
146 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 2 0.10 0 0.66
147 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 2 0.15 0 0.66
148 INT74729 Binding of Mpz and Ptprj 1 1 0.06 0.15 0.66
149 INT74852 Chrm1 Positive_regulation of Localization of Abat 1 1 0.11 0 0.66
150 INT56669 Nts Regulation of Localization of Acot1 2 1 0.12 0 0.65
151 INT75764 Positive_regulation of DYT10 Positive_regulation of Phosphorylation of Plcb3 1 1 0.04 0.11 0.65
152 INT76089 IFNA1 Negative_regulation of Positive_regulation of ISYNA1 1 1 0.27 0.05 0.65
153 INT78663 Dlst Regulation of Nos1 1 2 0.19 0.91 0.65
154 INT82383 Penk Positive_regulation of Gene_expression of Il1f5 1 2 0.04 0 0.65
155 INT82385 Penk Positive_regulation of Gene_expression of Il1 1 2 0.07 0 0.65
156 INT76877 Binding of Slc3a1 and Slc8a1 1 1 0.02 0 0.64
157 INT102863 Prkaca Regulation of Srgn 1 1 0.50 0.05 0.64
158 INT76026 Binding of Cyp2e1 and Cyp3a11 1 1 0.28 0.42 0.64
159 INT76688 Binding of CALCA and SNRPB 1 1 0.30 0 0.63
160 INT76761 Kctd1 Negative_regulation of RFFL 1 1 0.00 0.5 0.63
161 INT73381 Npy5r Positive_regulation of Positive_regulation of Npy 1 1 0.12 0 0.63
162 INT77529 PDYN Positive_regulation of Odc1 1 2 0.02 0 0.63
163 INT76087 IFNA1 Negative_regulation of ISYNA1 1 1 0.27 0.06 0.63
164 INT79210 Hps4 Negative_regulation of Mme 1 1 0.00 0 0.62
165 INT77120 Pomc Regulation of HYAL1 1 1 0.01 0 0.61
166 INT74395 Htr2b Negative_regulation of Pdyn 1 1 0.03 0 0.61
167 INT76458 Binding of Oprd1 and Coq10a 1 1 0.01 0.08 0.6
168 INT81228 Negative_regulation of Adk Positive_regulation of Ado 1 1 0.04 0.26 0.59
169 INT75092 Cck Regulation of Localization of Sst 1 1 0.01 0 0.59
170 INT77376 Tmie Negative_regulation of Mastl 1 1 0.01 0 0.59
171 INT75093 Gast Regulation of Localization of Sst 1 1 0.00 0 0.59
172 INT76237 Olr594 Positive_regulation of Gene_expression of Fos 1 1 0.05 0.09 0.59
173 INT77379 Tmie Negative_regulation of Ebp 1 1 0.03 0 0.59
174 INT77380 Tmie Negative_regulation of Fbln5 1 1 0.01 0 0.59
175 INT73073 Binding of Cd3e and Oprk1 1 1 0.28 0.06 0.59
176 INT73654 Binding of Jun and Pim3 1 2 0.02 0.99 0.58
177 INT102864 Prkaca Regulation of Twist1 1 1 0.48 0.05 0.58
178 INT76379 Negative_regulation of Binding of Cit and Flvcr2 1 1 0.11 0.08 0.58
179 INT73707 Ngf Regulation of Scgb1a1 1 1 0.25 0.61 0.58
180 INT78580 Binding of Adra2b and Oprd1 1 1 0.01 0.07 0.57
181 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 1 0.05 0.76 0.57
182 INT75128 Pnoc Regulation of Localization of Oxt 1 1 0.19 0 0.57
183 INT75490 LEPRE1 Positive_regulation of Gene_expression of COL7A1 1 1 0.03 0.52 0.57
184 INT76377 Regulation of Binding of Cit and Flvcr2 1 1 0.07 0.09 0.57
185 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 1 0.01 0.33 0.56
186 INT76248 Tac1 Positive_regulation of Gene_expression of Fos 1 1 0.34 0.34 0.56
187 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 2 0.42 0.97 0.56
188 INT75992 Binding of Pvalb and Lgals3 1 1 0.00 0 0.56
189 INT73368 Ang1 Negative_regulation of Fabp6 1 1 0.00 0.44 0.56
190 INT73920 Binding of CCNT1 and CYP2B6 1 1 0.19 0.17 0.56
191 INT77394 Binding of ARRB1 and GIPC1 1 1 0.01 0 0.56
192 INT78973 Prkcg Positive_regulation of Positive_regulation of Ina 1 1 0.10 0.07 0.55
193 INT78030 Binding of VEGFC and FCAMR 1 1 0.01 0.31 0.55
194 INT78587 Binding of Nfkb1 and Nos2 1 1 0.01 0.33 0.55
195 INT54584 GNRH1 Positive_regulation of FSHR 3 1 0.48 2.02 0.54
196 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 1 0.05 0.16 0.54
197 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 1 0.09 0.5 0.54
198 INT73367 Agt Negative_regulation of Localization of Calca 1 1 0.43 0.26 0.54
199 INT75129 Pnoc Negative_regulation of Avp 1 1 0.13 0 0.54
200 INT75127 Pnoc Negative_regulation of Oxt 1 1 0.15 0 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported in 1998. They are ordered first by their pain relevance and then by number of times they were reported in 1998. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 1998 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 155 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 48 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 93 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 31 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 28 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 35 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 36 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 41 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 66 1163 0.70 319.28 684
10 INT292 Localization of Penk 17 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 1 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 45 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 34 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 48 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 54 934 0.70 209.8 503.87
16 INT155 Positive_regulation of Prl 23 1233 0.70 317.93 457.82
17 INT1045 Localization of LH 29 1211 0.81 87.04 456.25
18 INT443 Localization of POMC 26 1020 0.81 284.52 443.17
19 INT50058 Negative_regulation of Cpox 42 907 0.58 426.28 428.29
20 INT9238 Gene_expression of IL6 30 1575 0.78 1135.66 424.22
21 INT4758 Positive_regulation of Localization of Calca 18 557 0.70 138.55 411.04
22 INT5895 Gene_expression of Oprm1 11 525 0.78 120.67 407.29
23 INT64202 Positive_regulation of Trpv1 2 643 0.70 249.66 397.42
24 INT467 Gene_expression of POMC 34 1048 0.78 332.8 394.16
25 INT1395 Negative_regulation of Penk 33 537 0.59 87.33 389.81
26 INT6056 Negative_regulation of Gene_expression of Fos 31 601 0.59 193.05 386.84
27 INT76660 Gene_expression of Trpv1 1 691 0.78 329.46 386.42
28 INT2540 Negative_regulation of Calca 27 538 0.59 172.11 384.38
29 INT6580 Negative_regulation of Ptgs1 46 929 0.59 381.53 376.26
30 INT157 Positive_regulation of Localization of Prl 4 790 0.70 104.54 374.78
31 INT287 Localization of Cck 32 518 0.81 86.84 364.04
32 INT439 Localization of Gnrh1 41 976 0.81 100.96 363.25
33 INT720 Positive_regulation of POMC 24 807 0.70 237.37 353.83
34 INT5660 Binding of Oprd1 23 477 0.48 71.86 342.06
35 INT876 Localization of Gh1 9 843 0.80 67.75 340.82
36 INT16260 Gene_expression of Bdnf 10 671 0.78 283.44 339.1
37 INT5235 Negative_regulation of TNF 10 924 0.59 772.91 331.98
38 INT2649 Regulation of Calca 12 433 0.62 146.05 330.95
39 INT5059 Positive_regulation of TNF 13 1050 0.70 896.51 322.81
40 INT162 Regulation of Prl 25 794 0.62 165.01 322.24
41 INT5979 Gene_expression of Oprd1 38 428 0.78 75.64 320.32
42 INT34869 Negative_regulation of PTGS2 16 778 0.59 366.76 319.85
43 INT5540 Positive_regulation of Oprm1 10 344 0.70 76.77 319.71
44 INT5680 Gene_expression of Ngf 8 530 0.78 264.29 310.56
45 INT4941 Positive_regulation of Oprd1 17 345 0.70 74.26 304.41
46 INT9131 Positive_regulation of Prkcg 10 431 0.70 130.8 302.41
47 INT477 Localization of Avp 24 813 0.81 131.58 300.4
48 INT161 Regulation of Localization of Prl 9 615 0.62 65.37 298.66
49 INT1352 Localization of Acot1 45 728 0.80 73.01 296.01
50 INT886 Gene_expression of Pomc 14 676 0.78 129.87 295.98
51 INT11624 Gene_expression of OPRM1 8 445 0.78 72.36 294.36
52 INT5379 Gene_expression of Fos 1 656 0.78 255.5 292.54
53 INT3579 Localization of Oxt 26 555 0.81 43.35 292.44
54 INT9158 Gene_expression of Tnf 16 722 0.78 522.01 277.68
55 INT2365 Positive_regulation of Cck 19 354 0.70 87.8 277.41
56 INT9381 Positive_regulation of TRPV1 3 523 0.70 187.4 276.05
57 INT49750 Negative_regulation of CPOX 38 735 0.58 360.06 274.19
58 INT6852 Localization of TNF 7 883 0.81 705.95 270.84
59 INT10832 Gene_expression of IL8 9 1050 0.78 698.72 270
60 INT1396 Binding of Penk 4 355 0.48 22.79 269.65
61 INT5591 Regulation of Gene_expression of Fos 31 425 0.62 129.06 265.78
62 INT9659 Gene_expression of Il6 8 991 0.78 715.11 265.57
63 INT5972 Gene_expression of IL1B 10 948 0.78 510.91 263.97
64 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
65 INT1893 Localization of Gh 12 1041 0.79 340.23 256.58
66 INT16868 Gene_expression of Il6 25 807 0.78 499.48 256.57
67 INT2909 Positive_regulation of Abat 17 334 0.70 62.1 256.43
68 INT3948 Regulation of Cck 18 291 0.62 58.07 255.88
69 INT5501 Regulation of Oprd1 18 283 0.62 55.1 249.9
70 INT1005 Localization of Sst 4 385 0.81 26.31 244.56
71 INT738 Regulation of POMC 10 459 0.62 111.19 243.74
72 INT1902 Gene_expression of Cck 22 348 0.78 70.33 241.92
73 INT11377 Positive_regulation of Ngf 18 331 0.70 206.5 238
74 INT1562 Localization of Crh 10 499 0.81 126.74 236.68
75 INT5597 Gene_expression of Pdyn 33 433 0.78 62.97 235.47
76 INT1665 Positive_regulation of Pag1 9 270 0.68 186.63 229.87
77 INT4759 Negative_regulation of Localization of Calca 11 294 0.59 82.62 226.45
78 INT9987 Gene_expression of Abat 6 296 0.78 95.46 226.34
79 INT6406 Binding of Oprm1 10 280 0.48 40.54 226.26
80 INT1212 Binding of Oprl1 10 312 0.48 28.6 225.15
81 INT11009 Phosphorylation of Creb1 11 458 0.82 111.34 221.97
82 INT626 Localization of CALCA 2 289 0.81 125.39 221.15
83 INT6665 Gene_expression of FOS 11 520 0.77 165.31 217.66
84 INT1308 Localization of Pomc 9 457 0.81 66.83 217.5
85 INT6293 Gene_expression of Oprm1 38 312 0.78 48.73 215.61
86 INT767 Localization of Gnrhr 27 565 0.80 106.68 214.57
87 INT4893 Gene_expression of Tacr1 8 366 0.78 129.67 213.92
88 INT22548 Positive_regulation of Casp3 6 483 0.70 258.78 213.07
89 INT6482 Positive_regulation of Gene_expression of TNF 11 659 0.70 569.88 210
90 INT16259 Positive_regulation of Bdnf 6 336 0.70 183.48 209.82
91 INT48955 Gene_expression of Nos2 9 753 0.78 403.87 208.08
92 INT2651 Positive_regulation of Pomc 4 403 0.70 95.72 206.24
93 INT2391 Negative_regulation of PTGS1 20 501 0.59 207.62 205.6
94 INT9132 Negative_regulation of Prkcg 10 279 0.59 88.05 203.47
95 INT798 Positive_regulation of Gene_expression of Penk 20 394 0.70 78.53 203.07
96 INT11313 Positive_regulation of Il6 24 526 0.70 331.27 201.59
97 INT2211 Negative_regulation of Abat 6 267 0.59 66.51 200.98
98 INT50670 Gene_expression of CPOX 39 763 0.76 442.13 195.02
99 INT156 Negative_regulation of Prl 13 542 0.59 131.97 192.24
100 INT528 Gene_expression of Prl 13 693 0.78 217.18 192.2
101 INT6488 Gene_expression of Tnf 18 484 0.78 339.61 191.58
102 INT2085 Positive_regulation of LH 7 441 0.70 60.15 191.02
103 INT6354 Localization of Gabrg1 11 321 0.74 41.41 186.74
104 INT1652 Regulation of Pomc 8 387 0.62 61.01 186.51
105 INT24326 Gene_expression of Ngf 22 346 0.78 218.67 184.71
106 INT10194 Positive_regulation of IL6 9 702 0.70 600.62 183.38
107 INT4803 Transcription of Penk 49 435 0.72 59.09 182.4
108 INT3440 Negative_regulation of Localization of Abat 10 221 0.57 33.94 180.36
109 INT12602 Negative_regulation of Oprm1 9 190 0.59 36.11 177.85
110 INT49441 Negative_regulation of Cpox 4 494 0.59 303.22 177.46
111 INT7506 Negative_regulation of Ltp 5 267 0.46 91.01 176.8
112 INT1429 Gene_expression of PDYN 11 308 0.78 61.33 175.65
113 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
114 INT943 Negative_regulation of Cck 6 205 0.59 38.42 174.78
115 INT26472 Regulation of Oprm1 9 191 0.62 35.84 173.1
116 INT15516 Gene_expression of Crp 9 711 0.77 615.33 173.09
117 INT5930 Positive_regulation of Oprm1 12 221 0.70 31.19 172.93
118 INT159 Negative_regulation of Localization of Prl 2 416 0.59 55.34 171.8
119 INT4937 Negative_regulation of Oprd1 12 224 0.59 44.51 171.11
120 INT438 Gene_expression of Crh 20 376 0.78 159.11 169.17
121 INT867 Gene_expression of IFNA1 3 930 0.78 594.85 168.03
122 INT739 Negative_regulation of POMC 12 358 0.59 102.28 166.77
123 INT55879 Gene_expression of CCL2 3 421 0.78 240.74 166.02
124 INT1114 Localization of Ins1 7 748 0.80 192.95 165.48
125 INT4768 Positive_regulation of OPRM1 4 212 0.70 31.09 164.28
126 INT2366 Binding of Cck 6 192 0.48 30.64 163.46
127 INT5127 Localization of Lhb 19 488 0.80 50.48 162.66
128 INT3448 Positive_regulation of Gh 11 521 0.69 180.03 161.18
129 INT5513 Negative_regulation of Pomc 10 295 0.59 60.9 158.63
130 INT51921 Gene_expression of Cpox 23 501 0.73 229.81 157.81
131 INT21185 Binding of Ptprg 34 213 0.47 13.49 157.75
132 INT66280 Gene_expression of Nos2 2 534 0.78 330.78 157.07
133 INT768 Positive_regulation of Oprl1 23 179 0.70 40.05 156.93
134 INT1303 Negative_regulation of Npr1 11 278 0.55 35.1 156.78
135 INT2640 Gene_expression of Pomc 15 424 0.78 120.72 155.37
136 INT6042 Binding of Oprm1 25 248 0.48 31.77 154.34
137 INT4740 Gene_expression of Th 5 298 0.78 61.27 154.03
138 INT2910 Regulation of Abat 5 169 0.62 36.95 153.53
139 INT1044 Negative_regulation of Localization of LH 10 358 0.59 25.95 151.31
140 INT4829 Positive_regulation of Localization of Abat 8 199 0.55 20.91 150.48
141 INT880 Positive_regulation of Localization of Gh1 2 304 0.70 14.79 150.23
142 INT15515 Positive_regulation of Crp 13 700 0.70 604.24 150.15
143 INT49134 Gene_expression of Grin1 7 270 0.78 84.78 148.61
144 INT5050 Regulation of Localization of Calca 2 149 0.62 41.25 148.57
145 INT6108 Gene_expression of Npy 18 292 0.78 110.65 148.21
146 INT13353 Positive_regulation of Tnf 9 332 0.70 248.75 148.1
147 INT7628 Gene_expression of Ltp 3 273 0.77 70.21 147.87
148 INT2451 Positive_regulation of Avp 5 355 0.70 102.66 147.69
149 INT1033 Positive_regulation of Ca2 3 507 0.68 131.76 147.64
150 INT9852 Positive_regulation of Gpt 7 563 0.70 364.64 146.82
151 INT5116 Gene_expression of IL2 7 670 0.78 291.13 146.69
152 INT812 Localization of INS 30 1026 0.81 515.6 145.31
153 INT425 Localization of PRL 6 455 0.81 189.64 144.8
154 INT2379 Positive_regulation of Localization of LH 11 349 0.70 27.86 144.53
155 INT3300 Positive_regulation of Gene_expression of Calca 1 179 0.70 77.76 144.2
156 INT2780 Regulation of Gene_expression of Penk 22 265 0.62 32.45 143.88
157 INT9660 Regulation of TNF 9 363 0.62 312.94 139.99
158 INT1414 Regulation of Oprl1 11 169 0.62 32.05 139.99
159 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
160 INT1273 Gene_expression of Avp 10 356 0.78 90.56 138.7
161 INT48895 Gene_expression of Il10 5 333 0.78 221.2 138.52
162 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
163 INT5061 Negative_regulation of Mme 7 306 0.59 51.97 136.9
164 INT4658 Binding of OPRM1 4 188 0.48 25.96 136.24
165 INT1047 Negative_regulation of LH 4 314 0.59 53.71 135.89
166 INT2541 Binding of Calca 13 200 0.48 67.14 134.62
167 INT11012 Positive_regulation of Creb1 3 258 0.70 84.4 132
168 INT48953 Positive_regulation of Nos2 6 486 0.70 239.85 131.87
169 INT5497 Positive_regulation of Crh 15 299 0.70 125.54 131.14
170 INT49439 Gene_expression of Cpox 4 508 0.73 326.97 130.17
171 INT5595 Positive_regulation of Pdyn 11 223 0.70 48.37 130.14
172 INT64161 Positive_regulation of Prkca 9 213 0.70 85.06 129.91
173 INT65600 Positive_regulation of Casp3 5 376 0.70 198.44 128.03
174 INT1614 Gene_expression of Oprl1 19 164 0.78 31.43 127.74
175 INT5842 Gene_expression of Gfap 2 372 0.78 153.71 127.71
176 INT1878 Binding of HLA-B 23 440 0.48 321.16 127.36
177 INT695 Binding of POMC 6 304 0.48 56.66 126.85
178 INT65054 Positive_regulation of Nfkb1 9 285 0.70 149.33 126.73
179 INT5931 Regulation of Oprm1 9 149 0.62 18.15 125.93
180 INT6822 Gene_expression of Pdyn 14 215 0.78 35.99 125.76
181 INT416 Regulation of LH 12 253 0.62 31.48 125.55
182 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
183 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
184 INT4259 Positive_regulation of Npr1 16 262 0.70 49.37 123.11
185 INT2106 Regulation of Localization of LH 8 279 0.62 22.37 122.77
186 INT252 Localization of GH1 19 529 0.80 227.4 122.05
187 INT6128 Positive_regulation of Localization of POMC 10 256 0.70 68.77 121.64
188 INT14151 Gene_expression of Casp3 2 311 0.78 140.26 120.68
189 INT218 Positive_regulation of Th 5 245 0.70 40.5 120.1
190 INT2555 Positive_regulation of Localization of Penk 9 116 0.70 24.35 119.73
191 INT8243 Positive_regulation of Il6 4 451 0.70 358.24 119.28
192 INT17612 Gene_expression of CRP 1 676 0.78 580.61 119.03
193 INT12501 Positive_regulation of Adarb1 9 166 0.58 36.94 118.92
194 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
195 INT9235 Negative_regulation of Gene_expression of TNF 7 346 0.59 252.98 118.61
196 INT50674 Gene_expression of PTGS2 19 459 0.78 253.33 118.51
197 INT7341 Positive_regulation of Grin1 3 169 0.70 65.86 118.38
198 INT7395 Localization of GNRH1 17 399 0.81 62.88 117.68
199 INT12339 Localization of IL8 3 437 0.81 251.87 117.39
200 INT1438 Localization of Pomc 11 360 0.81 101.26 116.47
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