Y:1999

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 1999. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 1999. They are ordered first by their pain relevance and then by number of times they were reported in 1999. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 1999 Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 2 0.54 5.93 32.4
2 INT69872 Binding of MC1R and POMC 52 8 0.54 8.87 18.3
3 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 2 0.73 0.87 14.34
4 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 2 0.64 2.12 14.2
5 INT26468 Ghrh Positive_regulation of Localization of Gh 21 6 0.37 3.26 9.21
6 INT21276 Binding of Oprd1 and Penk 9 1 0.54 1.14 8.28
7 INT84921 Binding of NGF and NTRK1 13 2 0.50 6.39 6.1
8 INT15842 Crh Positive_regulation of Localization of Pomc 15 2 0.73 5 5.05
9 INT1310 Pomc Regulation of Localization of Prl 9 1 0.40 0.61 4.96
10 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 1 0.59 9.37 4.48
11 INT16221 Ghrh Positive_regulation of Gh 8 2 0.21 1.89 4.08
12 INT82023 Binding of Ntrk1 and Ngf 5 2 0.53 3.48 3.92
13 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 1 0.55 1.84 3.71
14 INT15984 Binding of Avp and Oxt 11 1 0.32 1.33 3.64
15 INT85743 Pdyn Positive_regulation of Oprk1 3 1 0.32 2.12 3.52
16 INT3434 Vip Positive_regulation of Localization of Prl 6 2 0.76 0.16 3.21
17 INT85042 Binding of CCT6A and MAX 1 3 0.00 0 3.13
18 INT81708 POMC Regulation of Gene_expression of ITGAM 1 4 0.53 0.72 3.1
19 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 1 0.06 2.01 2.85
20 INT83169 Binding of Cck and Lep 7 2 0.42 1.58 2.78
21 INT81657 Binding of CPOX and PTGS1 5 2 0.15 1.9 2.37
22 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 4 0.01 0 2.26
23 INT85251 Chi3l1 Positive_regulation of Casp3 1 4 0.01 0 2.25
24 INT86179 TNF Positive_regulation of Localization of IL6 5 1 0.35 1.66 2.17
25 INT66803 Oxt Regulation of Avp 7 1 0.16 0.19 2.15
26 INT79470 Mgat4a Regulation of Localization of Calca 1 3 0.08 1.72 2.1
27 INT83425 Binding of CD40LG and IGHG3 11 8 0.21 4.56 2.09
28 INT85041 Binding of IGHG3 and MAX 1 2 0.00 0 2.09
29 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 2 0.39 0.87 2.05
30 INT83170 Lep Regulation of Cck 5 1 0.43 0.68 1.96
31 INT83418 Binding of OPRL1 and Ntrk1 1 2 0.02 0 1.91
32 INT81920 Binding of IL1B and NFKB1 1 2 0.04 1.54 1.85
33 INT81914 Binding of HSF1 and NFKB1 1 2 0.05 1.54 1.85
34 INT82867 Cck Regulation of Localization of Pgc 1 3 0.05 0 1.83
35 INT16891 GHRH Regulation of GH1 5 1 0.37 1.94 1.82
36 INT80787 Negative_regulation of Binding of Pnoc and Oprl1 2 1 0.39 0.39 1.72
37 INT80199 Ngf Regulation of Transcription of Rab38 1 2 0.01 1.48 1.68
38 INT83093 IL1B Positive_regulation of BDKRB1 1 2 0.51 0.44 1.65
39 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 1 0.08 4.21 1.61
40 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 2 0.50 0.34 1.57
41 INT81709 POMC Regulation of Gene_expression of ITGB2 1 2 0.40 0.34 1.57
42 INT81719 POMC Regulation of Gene_expression of ITGAL 1 2 0.35 0.34 1.57
43 INT81712 POMC Regulation of FCGR3B 1 2 0.16 0.34 1.56
44 INT81715 POMC Regulation of ITGB2 1 2 0.40 0.34 1.55
45 INT81721 POMC Regulation of ITGAM 1 2 0.39 0.34 1.55
46 INT81714 POMC Regulation of ITGAL 1 2 0.15 0.34 1.54
47 INT62481 Penk Negative_regulation of Slc6a7 2 1 0.60 0 1.5
48 INT83416 Binding of OPRK1 and Ntrk1 1 2 0.02 0 1.45
49 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 1 0.06 0.19 1.44
50 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 2 0.33 2.19 1.41
51 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 2 0.09 0 1.4
52 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 2 0.47 0.64 1.37
53 INT83197 Binding of Ntrk1 and Gdnf 1 2 0.01 1.05 1.36
54 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 2 0.20 0 1.33
55 INT85742 Pdyn Positive_regulation of Rbm39 1 1 0.01 0.17 1.29
56 INT31008 Crh Positive_regulation of Pomc 3 2 0.49 2.31 1.28
57 INT83707 Acyp2-ps1 Regulation of Casp3 1 2 0.17 0 1.28
58 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 2 0.17 0 1.28
59 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 4 0.12 2.55 1.26
60 INT84886 APC Regulation of PPARD 1 3 0.51 1.57 1.26
61 INT83422 Binding of FANCB and IGHG3 3 2 0.12 5.09 1.22
62 INT15578 GNRH1 Regulation of Localization of Lhb 3 1 0.07 0 1.22
63 INT79471 Mgat4a Regulation of Calca 1 2 0.06 1.09 1.21
64 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 1 0.39 0.3 1.21
65 INT81097 Akr1d1 Regulation of Localization of Abat 1 1 0.00 0 1.2
66 INT88193 Binding of IL2 and IL4 1 4 0.13 1.7 1.2
67 INT83428 Binding of ADIPOQ and FRTS 3 4 0.18 2.02 1.19
68 INT85780 Prkaca Regulation of Prkcg 1 1 0.29 0.47 1.17
69 INT84488 Negative_regulation of Binding of Cpe and Mif-ps1 1 2 0.06 0 1.13
70 INT84487 Binding of Cpe and Mif-ps1 1 2 0.05 0 1.13
71 INT83427 Binding of IGHG3 and FRTS 3 4 0.03 1.92 1.12
72 INT85744 Binding of Pdyn and Rbm39 1 1 0.01 0.16 1.12
73 INT83616 Binding of IL6 and IL8 5 2 0.09 5.8 1.11
74 INT102421 POMC Regulation of Gene_expression of Fos 1 1 0.12 0.34 1.11
75 INT81788 Binding of AGRP and MC4R 4 3 0.51 0 1.09
76 INT70495 CALCA Positive_regulation of CALCB 2 1 0.40 0 1.08
77 INT79323 Abat Regulation of Vmn2r1 1 1 0.00 0 1.08
78 INT79322 Penk Regulation of Vmn2r1 1 1 0.00 0 1.08
79 INT81583 Cyp3a23/3a1 Positive_regulation of st 1 1 0.04 0 1.08
80 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 1 0.01 0 1.08
81 INT85718 pcp Regulation of Npy 1 1 0.03 0 1.07
82 INT79094 PDYN Positive_regulation of PRL 1 1 0.35 0.09 1.07
83 INT81582 Plec Positive_regulation of st 1 1 0.02 0 1.07
84 INT81581 Plec Positive_regulation of Nudt14 1 1 0.01 0 1.07
85 INT83936 Binding of Mtap2 and Penk 1 2 0.22 0.19 1.07
86 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 1 0.00 0 1.06
87 INT82024 Binding of Ngfr and Ngf 2 1 0.33 1.48 1.05
88 INT85039 Binding of GPM6A and MAX 1 1 0.00 0 1.05
89 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 3 0.11 1.59 1.02
90 INT81545 Tnf Positive_regulation of Gtf3a 2 1 0.03 1.41 1.02
91 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 1 0.48 0.59 1.02
92 INT83903 Penk Positive_regulation of Npff 1 1 0.49 0 1.02
93 INT79602 Binding of PSMA5 and Oprd1 2 2 0.19 1.05 1.01
94 INT83987 Ngf Regulation of Atf2 1 2 0.52 0.49 1
95 INT86181 SFTPA1 Positive_regulation of IL6 1 1 0.07 0.32 0.99
96 INT85320 Binding of Avp and Vas1 1 1 0.00 0.87 0.98
97 INT85322 Binding of Vas1 and Vax2os2 1 1 0.00 0.87 0.97
98 INT81127 Binding of Gabrd and Abat 3 1 0.25 0 0.96
99 INT83415 Binding of Oprm1 and Ntrk1 1 1 0.01 0 0.96
100 INT77142 Binding of IFNG and IL4 2 2 0.03 1.16 0.95
101 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 1 0.06 0 0.94
102 INT84091 Negative_regulation of Nka1 Regulation of Vip 1 1 0.00 0 0.93
103 INT81919 Binding of HSF1 and IL1B 1 1 0.42 0.77 0.93
104 INT81329 Binding of ARRB1 and OPRK1 1 2 0.05 0.1 0.93
105 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 1 0.00 0 0.93
106 INT82124 IK Positive_regulation of Gene_expression of Oprd1 1 1 0.00 0 0.92
107 INT84089 Nka1 Regulation of Localization of Vip 1 1 0.00 0 0.92
108 INT84088 Nka1 Regulation of Vip 1 1 0.01 0 0.92
109 INT80718 Trpv3 Negative_regulation of Chn1 1 1 0.01 0.7 0.92
110 INT82120 IK Positive_regulation of CEBPB 1 1 0.00 0 0.92
111 INT85783 PRKG1 Regulation of Prkcg 1 1 0.09 0.38 0.9
112 INT80132 Binding of HLA-B and TNF 1 1 0.04 1.15 0.89
113 INT83417 Binding of OPRL1 and Oprm1 1 1 0.01 0 0.89
114 INT84369 Ngf Positive_regulation of KNG1 1 1 0.04 0.29 0.89
115 INT82125 IK Regulation of Gene_expression of Oprd1 1 1 0.00 0 0.88
116 INT71408 Binding of Rvm and Nts 2 1 0.27 1.21 0.87
117 INT80792 Prkcg Regulation of Oprd1 1 1 0.19 0.2 0.86
118 INT84414 Folr2 Regulation of Binding of Oprd1 and 1 1 0.03 0.18 0.84
119 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 1 0.01 0.08 0.84
120 INT80878 PCDHB17 Negative_regulation of ADCY1 1 1 0.01 0.08 0.84
121 INT84087 B3GAT1 Positive_regulation of Localization of SST 1 1 0.06 0 0.83
122 INT80793 Prkcg Regulation of Pkm2 1 1 0.29 0.2 0.83
123 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 1 0.09 0 0.83
124 INT84717 Il1b Regulation of Cpox 1 1 0.00 0.37 0.83
125 INT79617 Htr1a Positive_regulation of Localization of POMC 1 2 0.38 0 0.83
126 INT84103 TACR1 Regulation of Nka1 1 1 0.00 0 0.81
127 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 1 0.09 0.61 0.81
128 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 1 0.45 0.2 0.81
129 INT84104 TACR1 Negative_regulation of TACR1 Regulation of Nka1 1 1 0.00 0 0.81
130 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 1 0.11 1.88 0.8
131 INT84040 EGF Positive_regulation of CPOX 2 1 0.07 1.91 0.8
132 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 1 0.01 0.68 0.8
133 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 1 0.51 0.6 0.8
134 INT85686 Binding of Arrb1 and Arrb2 1 1 0.14 0.09 0.79
135 INT79743 Nts Positive_regulation of Positive_regulation of Sst 1 1 0.25 0 0.79
136 INT79742 Positive_regulation of Nts Positive_regulation of Sst 1 1 0.25 0 0.79
137 INT81716 ITGAL Regulation of ITGB2 2 2 0.30 1.24 0.78
138 INT81717 ITGAL Regulation of Gene_expression of ITGAM 1 1 0.30 0.17 0.78
139 INT81718 ITGAL Regulation of Gene_expression of FCGR3B 1 1 0.28 0.17 0.78
140 INT79339 Phax Regulation of Gene_expression of Tacr1 1 1 0.07 0 0.78
141 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 1 0.30 0.17 0.78
142 INT84466 DPP4 Regulation of Localization of Naga 1 1 0.00 0.87 0.78
143 INT79741 Nts Positive_regulation of Sst 1 1 0.25 0 0.78
144 INT72017 Binding of Adora2a and Ptprg 2 2 0.07 0 0.77
145 INT81976 Binding of GNA15 and OPRL1 1 2 0.02 0 0.77
146 INT81977 Binding of OPRL1 and Galphaqo5 1 2 0.01 0 0.77
147 INT81713 ITGAL Regulation of ITGAM 1 1 0.30 0.17 0.77
148 INT79532 Crh Regulation of Ugt1a10 1 1 0.00 0 0.76
149 INT81975 Binding of OPRL1 and RASGRP1 1 2 0.03 0 0.76
150 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 4 0.52 0.75 0.76
151 INT170127 Binding of ITGAL and PECAM1 2 1 0.01 2.71 0.75
152 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 1 0.11 0 0.75
153 INT81520 Binding of PNOC and Oprl1 1 1 0.24 0.1 0.75
154 INT81011 CNR1 Positive_regulation of Gene_expression of PENK 1 1 0.54 0 0.75
155 INT83868 Oprd1 Positive_regulation of Gene_expression of Fos 1 1 0.01 0 0.75
156 INT84283 Binding of Adra2a and Htr1f 1 1 0.16 0.15 0.74
157 INT84090 Nka1 Positive_regulation of Localization of Vip 1 1 0.00 0 0.74
158 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 1 0.02 0 0.74
159 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 1 0.12 0 0.72
160 INT83714 Adarb1 Positive_regulation of Localization of Sst 1 1 0.00 0.9 0.72
161 INT83956 Binding of Cxcl2 and Cxcr1 1 1 0.19 0.98 0.71
162 INT81735 Binding of Ins1 and Pomc 1 2 0.20 2.24 0.71
163 INT82767 Binding of HP and MLRG 1 1 0.00 0 0.71
164 INT83838 Binding of CEACAM6 and Il1b 1 1 0.05 0 0.71
165 INT82759 Binding of IGHG3 and OPRM1 2 1 0.06 0 0.7
166 INT82378 Sst Regulation of Localization of Pomc 1 1 0.23 0.6 0.7
167 INT84605 Binding of Avp and Avp Regulation of Aqp2 1 2 0.07 0 0.7
168 INT83957 Binding of Cxcr2 and Cxcl2 1 1 0.33 0.97 0.7
169 INT79744 Gtf3a Positive_regulation of Sst 1 1 0.09 0 0.7
170 INT81968 Binding of PLEK and Adra2a 1 1 0.07 0.1 0.7
171 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 1 0.06 1.09 0.7
172 INT82497 Binding of CRX and Nts 1 2 0.05 1.54 0.7
173 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 1 0.15 1.08 0.69
174 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 1 0.29 0.32 0.69
175 INT81769 Binding of Chrna4 and Neurod1 1 1 0.35 0.07 0.69
176 INT81787 Binding of AGRP and MC1R 1 6 0.53 0 0.69
177 INT82022 Binding of Trib3 and Ngf 1 1 0.08 0.31 0.68
178 INT82311 Binding of HADHA and Gast 1 1 0.03 0.37 0.68
179 INT82312 Negative_regulation of Binding of HADHA and Gast 1 1 0.04 0.37 0.68
180 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 1 0.07 0.31 0.68
181 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 1 0.20 0.15 0.68
182 INT81631 Selenbp2 Negative_regulation of Fas 1 1 0.03 0.77 0.67
183 INT84213 Cck Regulation of Cckbr 1 1 0.41 0 0.67
184 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 1 0.03 0.77 0.67
185 INT81832 Binding of ADRA2C and CRYGS 1 4 0.06 0 0.66
186 INT81407 Binding of Oprl1 and Insrr 1 1 0.02 0.13 0.66
187 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 2 0.07 0.94 0.66
188 INT38057 Binding of Crp and Esr1 2 1 0.04 1.21 0.65
189 INT45369 IGF1 Regulation of GH1 1 1 0.04 1.12 0.65
190 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 1 0.68 0.64 0.65
191 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 1 0.02 0 0.64
192 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 1 0.30 0 0.64
193 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 1 0.28 0.58 0.64
194 INT83806 Binding of Trpv1 and DRGX 1 1 0.02 0.62 0.62
195 INT83804 Binding of EPHB3 and DRGX 1 1 0.00 0.62 0.62
196 INT82267 Lif Regulation of Gene_expression of Gal 1 3 0.40 2.76 0.62
197 INT84771 Positive_regulation of Binding of App and Pag1 1 1 0.17 0.9 0.62
198 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 1 0.11 0 0.61
199 INT82065 Negative_regulation of Gnrhr Negative_regulation of Localization of LH 1 1 0.45 0 0.61
200 INT82064 Negative_regulation of Gnrh1 Negative_regulation of Localization of LH 1 1 0.40 0 0.61

Single Events

The table below shows the top 100 pain related interactions that have been reported in 1999. They are ordered first by their pain relevance and then by number of times they were reported in 1999. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 1999 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 172 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 86 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 60 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 43 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 49 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 13 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 39 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 34 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 79 1163 0.70 319.28 684
10 INT292 Localization of Penk 10 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 12 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 22 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 32 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 16 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 56 934 0.70 209.8 503.87
16 INT155 Positive_regulation of Prl 26 1233 0.70 317.93 457.82
17 INT1045 Localization of LH 10 1211 0.81 87.04 456.25
18 INT443 Localization of POMC 24 1020 0.81 284.52 443.17
19 INT50058 Negative_regulation of Cpox 38 907 0.58 426.28 428.29
20 INT9238 Gene_expression of IL6 30 1575 0.78 1135.66 424.22
21 INT4758 Positive_regulation of Localization of Calca 21 557 0.70 138.55 411.04
22 INT5895 Gene_expression of Oprm1 7 525 0.78 120.67 407.29
23 INT64202 Positive_regulation of Trpv1 3 643 0.70 249.66 397.42
24 INT467 Gene_expression of POMC 26 1048 0.78 332.8 394.16
25 INT1395 Negative_regulation of Penk 8 537 0.59 87.33 389.81
26 INT6056 Negative_regulation of Gene_expression of Fos 41 601 0.59 193.05 386.84
27 INT2540 Negative_regulation of Calca 21 538 0.59 172.11 384.38
28 INT18357 Gene_expression of TRPV1 11 825 0.78 307.11 382.81
29 INT6580 Negative_regulation of Ptgs1 42 929 0.59 381.53 376.26
30 INT157 Positive_regulation of Localization of Prl 11 790 0.70 104.54 374.78
31 INT287 Localization of Cck 54 518 0.81 86.84 364.04
32 INT439 Localization of Gnrh1 7 976 0.81 100.96 363.25
33 INT720 Positive_regulation of POMC 19 807 0.70 237.37 353.83
34 INT5660 Binding of Oprd1 19 477 0.48 71.86 342.06
35 INT876 Localization of Gh1 4 843 0.80 67.75 340.82
36 INT16260 Gene_expression of Bdnf 10 671 0.78 283.44 339.1
37 INT5235 Negative_regulation of TNF 7 924 0.59 772.91 331.98
38 INT2649 Regulation of Calca 18 433 0.62 146.05 330.95
39 INT5059 Positive_regulation of TNF 21 1050 0.70 896.51 322.81
40 INT162 Regulation of Prl 16 794 0.62 165.01 322.24
41 INT5979 Gene_expression of Oprd1 22 428 0.78 75.64 320.32
42 INT34869 Negative_regulation of PTGS2 33 778 0.59 366.76 319.85
43 INT5540 Positive_regulation of Oprm1 8 344 0.70 76.77 319.71
44 INT5680 Gene_expression of Ngf 20 530 0.78 264.29 310.56
45 INT4941 Positive_regulation of Oprd1 18 345 0.70 74.26 304.41
46 INT9131 Positive_regulation of Prkcg 22 431 0.70 130.8 302.41
47 INT477 Localization of Avp 14 813 0.81 131.58 300.4
48 INT161 Regulation of Localization of Prl 20 615 0.62 65.37 298.66
49 INT63932 Positive_regulation of Ephb1 10 537 0.70 259.67 296.14
50 INT1352 Localization of Acot1 27 728 0.80 73.01 296.01
51 INT886 Gene_expression of Pomc 49 676 0.78 129.87 295.98
52 INT11624 Gene_expression of OPRM1 15 445 0.78 72.36 294.36
53 INT5379 Gene_expression of Fos 19 656 0.78 255.5 292.54
54 INT3579 Localization of Oxt 9 555 0.81 43.35 292.44
55 INT9158 Gene_expression of Tnf 30 722 0.78 522.01 277.68
56 INT2365 Positive_regulation of Cck 29 354 0.70 87.8 277.41
57 INT9381 Positive_regulation of TRPV1 6 523 0.70 187.4 276.05
58 INT49750 Negative_regulation of CPOX 48 735 0.58 360.06 274.19
59 INT6852 Localization of TNF 11 883 0.81 705.95 270.84
60 INT10832 Gene_expression of IL8 19 1050 0.78 698.72 270
61 INT1396 Binding of Penk 3 355 0.48 22.79 269.65
62 INT5591 Regulation of Gene_expression of Fos 36 425 0.62 129.06 265.78
63 INT9659 Gene_expression of Il6 4 991 0.78 715.11 265.57
64 INT5972 Gene_expression of IL1B 22 948 0.78 510.91 263.97
65 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
66 INT1893 Localization of Gh 49 1041 0.79 340.23 256.58
67 INT16868 Gene_expression of Il6 39 807 0.78 499.48 256.57
68 INT2909 Positive_regulation of Abat 9 334 0.70 62.1 256.43
69 INT3948 Regulation of Cck 26 291 0.62 58.07 255.88
70 INT5501 Regulation of Oprd1 25 283 0.62 55.1 249.9
71 INT1005 Localization of Sst 3 385 0.81 26.31 244.56
72 INT738 Regulation of POMC 4 459 0.62 111.19 243.74
73 INT1902 Gene_expression of Cck 15 348 0.78 70.33 241.92
74 INT11377 Positive_regulation of Ngf 20 331 0.70 206.5 238
75 INT1562 Localization of Crh 12 499 0.81 126.74 236.68
76 INT5597 Gene_expression of Pdyn 9 433 0.78 62.97 235.47
77 INT1665 Positive_regulation of Pag1 10 270 0.68 186.63 229.87
78 INT4759 Negative_regulation of Localization of Calca 11 294 0.59 82.62 226.45
79 INT9987 Gene_expression of Abat 7 296 0.78 95.46 226.34
80 INT6406 Binding of Oprm1 12 280 0.48 40.54 226.26
81 INT1212 Binding of Oprl1 15 312 0.48 28.6 225.15
82 INT11009 Phosphorylation of Creb1 2 458 0.82 111.34 221.97
83 INT626 Localization of CALCA 5 289 0.81 125.39 221.15
84 INT6665 Gene_expression of FOS 15 520 0.77 165.31 217.66
85 INT1308 Localization of Pomc 35 457 0.81 66.83 217.5
86 INT6293 Gene_expression of Oprm1 21 312 0.78 48.73 215.61
87 INT6481 Binding of TNF 3 624 0.48 510.2 214.82
88 INT767 Localization of Gnrhr 5 565 0.80 106.68 214.57
89 INT4893 Gene_expression of Tacr1 20 366 0.78 129.67 213.92
90 INT22548 Positive_regulation of Casp3 3 483 0.70 258.78 213.07
91 INT6482 Positive_regulation of Gene_expression of TNF 10 659 0.70 569.88 210
92 INT16259 Positive_regulation of Bdnf 4 336 0.70 183.48 209.82
93 INT48955 Gene_expression of Nos2 30 753 0.78 403.87 208.08
94 INT2651 Positive_regulation of Pomc 26 403 0.70 95.72 206.24
95 INT2391 Negative_regulation of PTGS1 28 501 0.59 207.62 205.6
96 INT9132 Negative_regulation of Prkcg 9 279 0.59 88.05 203.47
97 INT798 Positive_regulation of Gene_expression of Penk 12 394 0.70 78.53 203.07
98 INT11313 Positive_regulation of Il6 19 526 0.70 331.27 201.59
99 INT2211 Negative_regulation of Abat 6 267 0.59 66.51 200.98
100 INT50670 Gene_expression of CPOX 48 763 0.76 442.13 195.02
101 INT156 Negative_regulation of Prl 12 542 0.59 131.97 192.24
102 INT528 Gene_expression of Prl 17 693 0.78 217.18 192.2
103 INT6488 Gene_expression of Tnf 2 484 0.78 339.61 191.58
104 INT2085 Positive_regulation of LH 5 441 0.70 60.15 191.02
105 INT63934 Phosphorylation of Ephb1 4 377 0.82 150.52 188.66
106 INT6354 Localization of Gabrg1 4 321 0.74 41.41 186.74
107 INT1652 Regulation of Pomc 22 387 0.62 61.01 186.51
108 INT24326 Gene_expression of Ngf 12 346 0.78 218.67 184.71
109 INT10194 Positive_regulation of IL6 12 702 0.70 600.62 183.38
110 INT4803 Transcription of Penk 17 435 0.72 59.09 182.4
111 INT3440 Negative_regulation of Localization of Abat 13 221 0.57 33.94 180.36
112 INT12602 Negative_regulation of Oprm1 12 190 0.59 36.11 177.85
113 INT49441 Negative_regulation of Cpox 17 494 0.59 303.22 177.46
114 INT7506 Negative_regulation of Ltp 9 267 0.46 91.01 176.8
115 INT1429 Gene_expression of PDYN 14 308 0.78 61.33 175.65
116 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
117 INT943 Negative_regulation of Cck 16 205 0.59 38.42 174.78
118 INT26472 Regulation of Oprm1 8 191 0.62 35.84 173.1
119 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
120 INT5930 Positive_regulation of Oprm1 14 221 0.70 31.19 172.93
121 INT159 Negative_regulation of Localization of Prl 8 416 0.59 55.34 171.8
122 INT4937 Negative_regulation of Oprd1 8 224 0.59 44.51 171.11
123 INT438 Gene_expression of Crh 11 376 0.78 159.11 169.17
124 INT867 Gene_expression of IFNA1 2 930 0.78 594.85 168.03
125 INT739 Negative_regulation of POMC 7 358 0.59 102.28 166.77
126 INT55879 Gene_expression of CCL2 8 421 0.78 240.74 166.02
127 INT1114 Localization of Ins1 3 748 0.80 192.95 165.48
128 INT4768 Positive_regulation of OPRM1 3 212 0.70 31.09 164.28
129 INT2366 Binding of Cck 16 192 0.48 30.64 163.46
130 INT5127 Localization of Lhb 10 488 0.80 50.48 162.66
131 INT3448 Positive_regulation of Gh 21 521 0.69 180.03 161.18
132 INT5513 Negative_regulation of Pomc 6 295 0.59 60.9 158.63
133 INT51921 Gene_expression of Cpox 27 501 0.73 229.81 157.81
134 INT21185 Binding of Ptprg 37 213 0.47 13.49 157.75
135 INT66280 Gene_expression of Nos2 1 534 0.78 330.78 157.07
136 INT768 Positive_regulation of Oprl1 5 179 0.70 40.05 156.93
137 INT1303 Negative_regulation of Npr1 9 278 0.55 35.1 156.78
138 INT2640 Gene_expression of Pomc 6 424 0.78 120.72 155.37
139 INT6042 Binding of Oprm1 12 248 0.48 31.77 154.34
140 INT4740 Gene_expression of Th 6 298 0.78 61.27 154.03
141 INT2910 Regulation of Abat 6 169 0.62 36.95 153.53
142 INT1044 Negative_regulation of Localization of LH 7 358 0.59 25.95 151.31
143 INT4829 Positive_regulation of Localization of Abat 6 199 0.55 20.91 150.48
144 INT880 Positive_regulation of Localization of Gh1 2 304 0.70 14.79 150.23
145 INT15515 Positive_regulation of Crp 20 700 0.70 604.24 150.15
146 INT49134 Gene_expression of Grin1 9 270 0.78 84.78 148.61
147 INT5050 Regulation of Localization of Calca 9 149 0.62 41.25 148.57
148 INT6108 Gene_expression of Npy 19 292 0.78 110.65 148.21
149 INT13353 Positive_regulation of Tnf 16 332 0.70 248.75 148.1
150 INT7628 Gene_expression of Ltp 3 273 0.77 70.21 147.87
151 INT2451 Positive_regulation of Avp 9 355 0.70 102.66 147.69
152 INT1033 Positive_regulation of Ca2 14 507 0.68 131.76 147.64
153 INT9852 Positive_regulation of Gpt 11 563 0.70 364.64 146.82
154 INT5116 Gene_expression of IL2 11 670 0.78 291.13 146.69
155 INT812 Localization of INS 5 1026 0.81 515.6 145.31
156 INT425 Localization of PRL 9 455 0.81 189.64 144.8
157 INT2379 Positive_regulation of Localization of LH 1 349 0.70 27.86 144.53
158 INT3300 Positive_regulation of Gene_expression of Calca 3 179 0.70 77.76 144.2
159 INT2780 Regulation of Gene_expression of Penk 9 265 0.62 32.45 143.88
160 INT60694 Gene_expression of Il10 3 567 0.78 369.48 143.69
161 INT9660 Regulation of TNF 8 363 0.62 312.94 139.99
162 INT1414 Regulation of Oprl1 4 169 0.62 32.05 139.99
163 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
164 INT1273 Gene_expression of Avp 17 356 0.78 90.56 138.7
165 INT48895 Gene_expression of Il10 2 333 0.78 221.2 138.52
166 INT2867 Gene_expression of CALCA 11 247 0.78 78.78 138.47
167 INT5061 Negative_regulation of Mme 6 306 0.59 51.97 136.9
168 INT4658 Binding of OPRM1 8 188 0.48 25.96 136.24
169 INT1047 Negative_regulation of LH 1 314 0.59 53.71 135.89
170 INT2541 Binding of Calca 6 200 0.48 67.14 134.62
171 INT60126 Regulation of Trpv1 5 186 0.62 85.53 133.4
172 INT11012 Positive_regulation of Creb1 1 258 0.70 84.4 132
173 INT48953 Positive_regulation of Nos2 14 486 0.70 239.85 131.87
174 INT5497 Positive_regulation of Crh 8 299 0.70 125.54 131.14
175 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
176 INT49439 Gene_expression of Cpox 11 508 0.73 326.97 130.17
177 INT5595 Positive_regulation of Pdyn 6 223 0.70 48.37 130.14
178 INT64161 Positive_regulation of Prkca 3 213 0.70 85.06 129.91
179 INT65600 Positive_regulation of Casp3 5 376 0.70 198.44 128.03
180 INT1614 Gene_expression of Oprl1 8 164 0.78 31.43 127.74
181 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
182 INT1878 Binding of HLA-B 11 440 0.48 321.16 127.36
183 INT695 Binding of POMC 6 304 0.48 56.66 126.85
184 INT65054 Positive_regulation of Nfkb1 7 285 0.70 149.33 126.73
185 INT5931 Regulation of Oprm1 8 149 0.62 18.15 125.93
186 INT6822 Gene_expression of Pdyn 5 215 0.78 35.99 125.76
187 INT416 Regulation of LH 4 253 0.62 31.48 125.55
188 INT5008 Localization of Calca 3 204 0.81 80.35 125.16
189 INT6323 Positive_regulation of Gabrg1 4 213 0.70 45.08 124.34
190 INT4824 Positive_regulation of Tacr1 13 169 0.70 66.1 123.46
191 INT4259 Positive_regulation of Npr1 7 262 0.70 49.37 123.11
192 INT2106 Regulation of Localization of LH 2 279 0.62 22.37 122.77
193 INT252 Localization of GH1 18 529 0.80 227.4 122.05
194 INT6128 Positive_regulation of Localization of POMC 6 256 0.70 68.77 121.64
195 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
196 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
197 INT218 Positive_regulation of Th 9 245 0.70 40.5 120.1
198 INT64201 Negative_regulation of Trpv1 4 203 0.59 79.18 119.75
199 INT2555 Positive_regulation of Localization of Penk 2 116 0.70 24.35 119.73
200 INT8243 Positive_regulation of Il6 3 451 0.70 358.24 119.28
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