Y:2002

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 2002. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 2002. They are ordered first by their pain relevance and then by number of times they were reported in 2002. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 2002 Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 1 0.54 5.93 32.4
2 INT69872 Binding of MC1R and POMC 52 10 0.54 8.87 18.3
3 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 1 0.73 0.87 14.34
4 INT106676 Binding of Trpv1 and Phax 18 1 0.34 4.19 12.36
5 INT68514 Pnoc Positive_regulation of Oprl1 10 1 0.59 3.56 9.57
6 INT26468 Ghrh Positive_regulation of Localization of Gh 21 4 0.37 3.26 9.21
7 INT21276 Binding of Oprd1 and Penk 9 1 0.54 1.14 8.28
8 INT106559 Binding of Bdnf and Ntrk2 23 2 0.43 11.09 7.33
9 INT91538 Pomc Positive_regulation of P9Ehs1 6 3 0.11 1.47 6.23
10 INT102122 Binding of Calca and RT1-M4 7 1 0.29 5.83 4.94
11 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 6 0.59 9.37 4.48
12 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 2 0.30 0.91 4.18
13 INT16221 Ghrh Positive_regulation of Gh 8 4 0.21 1.89 4.08
14 INT101942 Binding of CD40 and CD40LG 16 2 0.23 15.24 4.01
15 INT61359 TNF Positive_regulation of NFKB1 11 1 0.63 6.66 3.89
16 INT104977 MITF Regulation of Gene_expression of MC1R 1 5 0.69 0.91 3.71
17 INT17317 Binding of Jun and Fos 7 1 0.42 1.03 3.5
18 INT152035 Binding of HLA-A and MRAP 2 4 0.31 6.95 3.4
19 INT64719 IL1B Positive_regulation of IL6 7 1 0.41 6.84 3.14
20 INT101408 Binding of Grin1 and Olr1469 1 4 0.03 0.86 3.1
21 INT101407 Binding of Grin1 and Spr 1 4 0.14 0.86 3.09
22 INT1151 Binding of CCK and GAST 7 4 0.49 0.73 3.08
23 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 4 0.34 0 3.01
24 INT102284 Binding of Grin1 and Grin2a 5 1 0.27 1.79 3.01
25 INT106837 Binding of Oprm1 and Arrb2 3 2 0.32 0.83 3.01
26 INT100835 Binding of Calca and Akap12 1 6 0.07 0.41 2.92
27 INT106560 Binding of Ntf3 and Ntrk2 3 2 0.14 2.47 2.84
28 INT103669 Hps4 Positive_regulation of Mors1 1 2 0.01 0 2.7
29 INT104219 SCD Positive_regulation of Cnr1 1 2 0.00 2.67 2.54
30 INT104218 SCD Positive_regulation of CNR2 1 2 0.01 2.67 2.54
31 INT103330 Ngf Positive_regulation of Gdnf 2 1 0.28 1.27 2.45
32 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 1 0.09 2.6 2.4
33 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 1 0.23 0 2.35
34 INT103548 Binding of TRPV1 and TRPV3 3 1 0.37 1.82 2.28
35 INT106558 Binding of Ntrk2 and Ntrk3 3 2 0.52 2.51 2.28
36 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 1 0.12 0 2.19
37 INT64750 Binding of Oprm1 and Pck1 2 2 0.41 0.51 2.07
38 INT107268 Binding of ITGAL and NCR3 1 2 0.01 2.76 2.07
39 INT83170 Lep Regulation of Cck 5 2 0.43 0.68 1.96
40 INT104855 Prkaca Regulation of TRPV1 3 1 0.06 1.52 1.92
41 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 1 0.05 7.39 1.91
42 INT105716 Vta1 Regulation of Nfasc 1 3 0.14 0 1.89
43 INT100771 Binding of Itga1 and Vcam1 3 2 0.11 3.91 1.79
44 INT104710 Em Positive_regulation of Rbm39 1 1 0.02 0.07 1.76
45 INT104709 Msh3 Positive_regulation of Rbm39 1 1 0.01 0.07 1.76
46 INT102160 Binding of Mmp2 and Mmp9 3 1 0.28 2.87 1.75
47 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 2 0.50 4.37 1.69
48 INT56134 CALCA Positive_regulation of POMC 2 1 0.71 0.72 1.68
49 INT102447 Binding of CALCA and CALCRL 2 1 0.26 0.33 1.67
50 INT105917 Binding of SLC22A6 and SLC22A8 2 1 0.31 0.34 1.67
51 INT101926 Binding of Dio1 and Drd2 4 2 0.28 0.39 1.66
52 INT108066 Binding of NTRK1 and Ngf 3 2 0.33 2.56 1.66
53 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 1 0.17 0.38 1.65
54 INT172047 Binding of HLA-A and LRRC23 1 2 0.22 3.32 1.64
55 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 2 0.19 1.52 1.64
56 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 1 0.10 0.38 1.64
57 INT172206 Binding of Slc6a3 and ADHD1 2 1 0.03 2.76 1.61
58 INT107965 Binding of HLA-B and Mefv 2 1 0.34 3.91 1.61
59 INT105112 Plat Positive_regulation of JUN 1 3 0.01 1.55 1.58
60 INT106751 Pes1 Negative_regulation of Casp3 2 1 0.23 0 1.54
61 INT100784 RYBP Positive_regulation of CYP3A4 1 2 0.44 0 1.54
62 INT79021 Regulation of Binding of Jun and Fos 2 1 0.50 0.66 1.5
63 INT104975 MITF Regulation of Transcription of PRSS1 1 2 0.68 0.35 1.46
64 INT104972 MITF Regulation of Transcription of TYR 1 2 0.20 0.35 1.45
65 INT172203 Binding of Comt and Maoa 1 2 0.31 0.98 1.43
66 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 2 0.05 0 1.41
67 INT172834 Binding of IL6 and T2dm2 1 3 0.00 6.4 1.4
68 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 1 0.49 0.73 1.36
69 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 1 0.13 0.15 1.36
70 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 1 0.13 0.16 1.35
71 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 1 0.12 0.16 1.34
72 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 1 0.42 1.86 1.34
73 INT106839 Arrb2 Regulation of Oprm1 2 1 0.21 0.44 1.33
74 INT66428 Dcc Positive_regulation of Fos 2 1 0.05 0.39 1.29
75 INT108386 IL1B Positive_regulation of MMP1 3 1 0.27 1.56 1.28
76 INT100816 PPP1R14C Regulation of Ppp1cc 1 2 0.08 0 1.27
77 INT105295 WAS Regulation of PTGS1 1 1 0.02 0.13 1.27
78 INT104348 Pnoc Negative_regulation of Localization of Gnrh1 1 3 0.45 0 1.24
79 INT103031 Calca Positive_regulation of Ptgs1 2 1 0.46 0.98 1.22
80 INT105918 Binding of FUT1 and SLC9A3R2 1 1 0.00 0.14 1.2
81 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 2 0.01 2.38 1.2
82 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 2 0.06 2.38 1.2
83 INT172500 Ednra Positive_regulation of Coc 1 2 0.01 1 1.2
84 INT108064 Binding of Ngf and IgG-2a 1 2 0.01 2.36 1.19
85 INT55162 Binding of NFKB1 and RELA 10 1 0.30 2.82 1.18
86 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 2 0.07 1.18 1.16
87 INT106069 TH Positive_regulation of Th 1 1 0.07 0.16 1.14
88 INT102570 Abat Regulation of Gene_expression of Penk 3 2 0.13 0 1.12
89 INT104320 Binding of Adk and Ado 1 1 0.33 0.3 1.12
90 INT107269 Binding of HLA-A and NCR3 1 1 0.35 1.42 1.1
91 INT107264 Binding of TNF and NCR3 1 1 0.30 1.42 1.1
92 INT107266 Binding of HLA-DRB1 and TNF 1 1 0.29 1.41 1.1
93 INT107265 Binding of HLA-DRB1 and ITGAL 1 1 0.01 1.41 1.1
94 INT107263 Binding of HLA-DRB1 and NCR3 1 1 0.40 1.42 1.1
95 INT107267 Binding of HLA-A and TNF 1 1 0.34 1.41 1.1
96 INT101715 PLAT Positive_regulation of NFKB1 2 1 0.11 0.99 1.09
97 INT107562 Penk Positive_regulation of Localization of Il1b 1 1 0.20 0.09 1.09
98 INT107561 Mtr Positive_regulation of Localization of Il1b 1 1 0.04 0.09 1.09
99 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 2 0.43 0 1.09
100 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 1 0.01 0.09 1.08
101 INT172508 Binding of Cnnm1 and Mir343 1 1 0.01 0.15 1.08
102 INT105690 Ngf Positive_regulation of TRPV1 1 1 0.05 1.43 1.08
103 INT100678 IL4 Positive_regulation of STAT6 1 4 0.49 2.63 1.08
104 INT77737 Pnoc Positive_regulation of Localization of Prl 3 1 0.55 0 1.07
105 INT107564 Hps4 Regulation of Localization of Il1b 1 1 0.01 0.1 1.07
106 INT107560 Penk Regulation of Localization of Il1b 1 1 0.18 0.1 1.07
107 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 1 0.38 0.97 1.06
108 INT105113 Plat Positive_regulation of NFKB1 1 2 0.03 1.06 1.06
109 INT100564 CRX Positive_regulation of Fos 1 2 0.04 0.89 1.06
110 INT105109 Cxcl12 Positive_regulation of JUN 1 2 0.01 1.07 1.05
111 INT107566 Penk Regulation of Hps4 1 1 0.00 0.1 1.04
112 INT107563 Penk Regulation of Mtr 1 1 0.00 0.1 1.04
113 INT107565 Hps4 Regulation of Mtr 1 1 0.00 0.1 1.04
114 INT101066 MAP3K15 Positive_regulation of CDCP1 1 1 0.03 0.46 1.03
115 INT104089 Vta1 Negative_regulation of Abat 1 1 0.14 0 1.03
116 INT101067 MAP3K15 Positive_regulation of MAPK1 1 1 0.21 0.47 1.03
117 INT74027 Creb1 Regulation of Jun 4 1 0.27 1.04 1.02
118 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 1 0.11 1.13 1.02
119 INT105101 Pdyn Regulation of Samd10 1 1 0.00 0 1.02
120 INT101381 POMC Regulation of Localization of IL8 1 2 0.28 1.49 1.02
121 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 2 0.08 0.54 1.02
122 INT101065 MAP3K15 Positive_regulation of JUN 1 1 0.43 0.46 1.02
123 INT106345 Igf1 Regulation of Localization of Acot1 1 2 0.06 0 1.02
124 INT106706 POMC Negative_regulation of Binding of FN1 and 1 1 0.19 0.79 1.02
125 INT101317 Binding of Selplg and Selp 1 4 0.02 3.72 1.01
126 INT106810 ZNF398 Positive_regulation of RECK 1 1 0.02 0.5 1.01
127 INT106809 ZNF398 Positive_regulation of Transcription of RECK 1 1 0.02 0.5 1.01
128 INT102690 IL1B Positive_regulation of ITGAL 1 2 0.05 0.87 0.99
129 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 4 0.78 1.23 0.98
130 INT103928 Binding of Cd28 and Trav6-3 3 2 0.03 0.55 0.98
131 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 1 0.08 1 0.98
132 INT106248 Binding of CCR5 and YY1 1 2 0.54 0.19 0.98
133 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 1 0.48 1.26 0.96
134 INT103833 Sp5 Positive_regulation of Fos 1 2 0.51 0 0.96
135 INT171264 TNF Positive_regulation of MMP1 2 1 0.10 2.05 0.95
136 INT105668 Binding of AAVS1 and BDNF 1 1 0.08 0.94 0.95
137 INT100018 TNF Positive_regulation of MAPK1 3 1 0.24 1.56 0.94
138 INT77859 EDN1 Positive_regulation of MC1R 2 1 0.64 0.34 0.94
139 INT106707 POMC Regulation of Binding of LAMB2 and 1 1 0.03 0.7 0.94
140 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 2 0.21 0.93 0.94
141 INT103933 Cps1 Negative_regulation of Gene_expression of Cd69 1 2 0.03 0.25 0.93
142 INT103930 Cps1 Negative_regulation of Gene_expression of Il2ra 1 2 0.02 0.25 0.93
143 INT107001 F2 Positive_regulation of PAR1 4 1 0.05 2.15 0.92
144 INT111078 Binding of Cnr1 and Cnr2 2 1 0.05 0 0.92
145 INT79123 Binding of Pnoc and Oprm1 3 1 0.14 0 0.91
146 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 1 0.42 0.67 0.89
147 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 1 0.01 0.28 0.88
148 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 1 0.42 0.65 0.87
149 INT104126 STAT3 Regulation of Phospho1 1 1 0.00 0.06 0.86
150 INT105282 Thop1 Positive_regulation of Protein_catabolism of Pnoc 1 1 0.17 0.1 0.85
151 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 1 0.47 0.74 0.85
152 INT105281 Negative_regulation of Thop1 Negative_regulation of Protein_catabolism of Pnoc 1 1 0.16 0.09 0.84
153 INT105970 GH1 Regulation of Ghsr 1 3 0.04 1.16 0.84
154 INT106457 SPOP Positive_regulation of Negative_regulation of ADRA1D 1 1 0.02 0.56 0.84
155 INT105435 TNF Positive_regulation of IL6 5 2 0.25 4.45 0.83
156 INT105280 Negative_regulation of Thop1 Negative_regulation of Positive_regulation of Pnoc 1 1 0.14 0.09 0.83
157 INT106808 RECK Negative_regulation of MMP2 1 1 0.40 0.5 0.83
158 INT102931 Nos3 Positive_regulation of Nos2 1 2 0.43 1.63 0.83
159 INT106312 NFKB1 Regulation of S100A4 1 2 0.14 1.1 0.83
160 INT65011 IL1B Positive_regulation of PTGER2 4 1 0.08 0.92 0.82
161 INT94331 IFNG Positive_regulation of CXCL10 4 1 0.11 1.31 0.82
162 INT102201 Tnf Regulation of Il1b 3 1 0.39 2.57 0.82
163 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 1 0.22 0 0.82
164 INT102932 Nos3 Positive_regulation of NOS1 1 2 0.03 1.63 0.82
165 INT103178 Mastl Positive_regulation of Localization of Calca 1 1 0.13 0.36 0.81
166 INT107246 Ngf Regulation of Transcription of ASIC1 1 1 0.01 0.57 0.81
167 INT100677 IL13 Positive_regulation of STAT6 1 3 0.36 1.95 0.81
168 INT103331 Ngf Positive_regulation of Gdnf 1 1 0.01 0.57 0.8
169 INT100559 Binding of Grin1 and LOC502940 1 1 0.13 0.61 0.8
170 INT104831 Binding of GLI2 and NFKB1 1 5 0.08 0 0.8
171 INT106838 Lyar Regulation of Oprm1 1 1 0.04 0.28 0.8
172 INT101439 Cck Positive_regulation of Agtr2 1 1 0.24 0.33 0.8
173 INT105249 Cyb5b Positive_regulation of Localization of Prl 1 1 0.04 0 0.79
174 INT105250 Cyb5b Regulation of Localization of Gh1 1 1 0.00 0 0.79
175 INT103277 MGAT5B Positive_regulation of Gene_expression of IFNA1 1 1 0.01 0.87 0.78
176 INT102163 Binding of TNF and Mmp9 1 1 0.12 0.88 0.78
177 INT102161 Binding of TNF and Mmp2 1 1 0.10 0.88 0.78
178 INT102162 Binding of TNF and Adam17 1 1 0.14 0.88 0.78
179 INT100783 Binding of CYP2B6 and CYP3A4 2 1 0.17 2 0.77
180 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 1 0.02 0.53 0.77
181 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 1 0.00 0.07 0.77
182 INT102841 Pdcl Regulation of Oprd1 1 1 0.02 0.12 0.77
183 INT103333 Gdnf Regulation of TRPV1 1 1 0.02 0.53 0.77
184 INT103335 Ngf Regulation of TRPV1 1 1 0.05 0.53 0.77
185 INT104748 Ugt1a1 Regulation of Positive_regulation of LOC100359830 1 1 0.01 0.07 0.77
186 INT102159 Binding of Adam17 and Mmp2 1 1 0.18 0.87 0.77
187 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 1 0.57 1.4 0.76
188 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 1 0.43 1.34 0.76
189 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 5 0.03 0 0.76
190 INT107028 KNG1 Regulation of Des 1 1 0.01 1.7 0.76
191 INT104347 Pnoc Regulation of Localization of Gnrh1 1 2 0.57 0 0.75
192 INT106691 Ngf Positive_regulation of SIGMAR1 1 1 0.04 0 0.74
193 INT102086 TRNAI1 Negative_regulation of Positive_regulation of P2rx3 1 1 0.00 0.47 0.74
194 INT104974 MITF Positive_regulation of MC1R 1 1 0.52 0.16 0.74
195 INT170992 Binding of FN1 and MMRN1 3 1 0.01 2.13 0.73
196 INT111080 Binding of CA1 and CA2 2 1 0.02 1.62 0.73
197 INT106999 F2 Positive_regulation of PAR4 3 1 0.06 1.83 0.72
198 INT106992 F2 Positive_regulation of PARD3 3 1 0.05 1.83 0.72
199 INT103985 Binding of Gabrg1 and Cea 1 1 0.01 0 0.72
200 INT101676 Sst Negative_regulation of Localization of Gcg 1 1 0.03 0 0.72

Single Events

The table below shows the top 100 pain related interactions that have been reported in 2002. They are ordered first by their pain relevance and then by number of times they were reported in 2002. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 2002 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 180 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 72 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 67 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 45 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 60 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 23 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 57 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 43 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 65 1163 0.70 319.28 684
10 INT292 Localization of Penk 10 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 42 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 21 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 36 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 28 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 52 934 0.70 209.8 503.87
16 INT155 Positive_regulation of Prl 28 1233 0.70 317.93 457.82
17 INT1045 Localization of LH 15 1211 0.81 87.04 456.25
18 INT443 Localization of POMC 16 1020 0.81 284.52 443.17
19 INT50058 Negative_regulation of Cpox 137 907 0.58 426.28 428.29
20 INT9238 Gene_expression of IL6 60 1575 0.78 1135.66 424.22
21 INT4758 Positive_regulation of Localization of Calca 25 557 0.70 138.55 411.04
22 INT5895 Gene_expression of Oprm1 11 525 0.78 120.67 407.29
23 INT64202 Positive_regulation of Trpv1 17 643 0.70 249.66 397.42
24 INT467 Gene_expression of POMC 23 1048 0.78 332.8 394.16
25 INT1395 Negative_regulation of Penk 7 537 0.59 87.33 389.81
26 INT6056 Negative_regulation of Gene_expression of Fos 42 601 0.59 193.05 386.84
27 INT76660 Gene_expression of Trpv1 6 691 0.78 329.46 386.42
28 INT2540 Negative_regulation of Calca 21 538 0.59 172.11 384.38
29 INT18357 Gene_expression of TRPV1 38 825 0.78 307.11 382.81
30 INT6580 Negative_regulation of Ptgs1 70 929 0.59 381.53 376.26
31 INT157 Positive_regulation of Localization of Prl 20 790 0.70 104.54 374.78
32 INT287 Localization of Cck 7 518 0.81 86.84 364.04
33 INT439 Localization of Gnrh1 10 976 0.81 100.96 363.25
34 INT720 Positive_regulation of POMC 14 807 0.70 237.37 353.83
35 INT5660 Binding of Oprd1 19 477 0.48 71.86 342.06
36 INT876 Localization of Gh1 9 843 0.80 67.75 340.82
37 INT16260 Gene_expression of Bdnf 11 671 0.78 283.44 339.1
38 INT5235 Negative_regulation of TNF 18 924 0.59 772.91 331.98
39 INT2649 Regulation of Calca 11 433 0.62 146.05 330.95
40 INT5059 Positive_regulation of TNF 27 1050 0.70 896.51 322.81
41 INT162 Regulation of Prl 11 794 0.62 165.01 322.24
42 INT5979 Gene_expression of Oprd1 24 428 0.78 75.64 320.32
43 INT34869 Negative_regulation of PTGS2 97 778 0.59 366.76 319.85
44 INT5540 Positive_regulation of Oprm1 14 344 0.70 76.77 319.71
45 INT5680 Gene_expression of Ngf 29 530 0.78 264.29 310.56
46 INT46460 Gene_expression of NAV1 3 288 0.78 135.51 305.75
47 INT4941 Positive_regulation of Oprd1 19 345 0.70 74.26 304.41
48 INT9131 Positive_regulation of Prkcg 10 431 0.70 130.8 302.41
49 INT477 Localization of Avp 6 813 0.81 131.58 300.4
50 INT161 Regulation of Localization of Prl 16 615 0.62 65.37 298.66
51 INT63932 Positive_regulation of Ephb1 8 537 0.70 259.67 296.14
52 INT1352 Localization of Acot1 62 728 0.80 73.01 296.01
53 INT886 Gene_expression of Pomc 29 676 0.78 129.87 295.98
54 INT11624 Gene_expression of OPRM1 18 445 0.78 72.36 294.36
55 INT5379 Gene_expression of Fos 7 656 0.78 255.5 292.54
56 INT3579 Localization of Oxt 17 555 0.81 43.35 292.44
57 INT97367 Gene_expression of Nav1 4 243 0.78 132.97 286.66
58 INT9158 Gene_expression of Tnf 31 722 0.78 522.01 277.68
59 INT2365 Positive_regulation of Cck 5 354 0.70 87.8 277.41
60 INT9381 Positive_regulation of TRPV1 30 523 0.70 187.4 276.05
61 INT94450 Gene_expression of Nav1 1 359 0.78 131.85 275.46
62 INT49750 Negative_regulation of CPOX 19 735 0.58 360.06 274.19
63 INT6852 Localization of TNF 21 883 0.81 705.95 270.84
64 INT10832 Gene_expression of IL8 47 1050 0.78 698.72 270
65 INT1396 Binding of Penk 8 355 0.48 22.79 269.65
66 INT5591 Regulation of Gene_expression of Fos 28 425 0.62 129.06 265.78
67 INT9659 Gene_expression of Il6 15 991 0.78 715.11 265.57
68 INT5972 Gene_expression of IL1B 40 948 0.78 510.91 263.97
69 INT68684 Gene_expression of VEGFA 39 2371 0.78 1742.52 259.2
70 INT87687 Positive_regulation of Trpv1 8 409 0.70 210.24 257.59
71 INT1893 Localization of Gh 16 1041 0.79 340.23 256.58
72 INT16868 Gene_expression of Il6 26 807 0.78 499.48 256.57
73 INT2909 Positive_regulation of Abat 5 334 0.70 62.1 256.43
74 INT3948 Regulation of Cck 10 291 0.62 58.07 255.88
75 INT5501 Regulation of Oprd1 18 283 0.62 55.1 249.9
76 INT1005 Localization of Sst 9 385 0.81 26.31 244.56
77 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
78 INT1902 Gene_expression of Cck 10 348 0.78 70.33 241.92
79 INT11377 Positive_regulation of Ngf 12 331 0.70 206.5 238
80 INT1562 Localization of Crh 9 499 0.81 126.74 236.68
81 INT5597 Gene_expression of Pdyn 15 433 0.78 62.97 235.47
82 INT1665 Positive_regulation of Pag1 7 270 0.68 186.63 229.87
83 INT4759 Negative_regulation of Localization of Calca 12 294 0.59 82.62 226.45
84 INT9987 Gene_expression of Abat 6 296 0.78 95.46 226.34
85 INT6406 Binding of Oprm1 3 280 0.48 40.54 226.26
86 INT1212 Binding of Oprl1 5 312 0.48 28.6 225.15
87 INT11009 Phosphorylation of Creb1 37 458 0.82 111.34 221.97
88 INT626 Localization of CALCA 20 289 0.81 125.39 221.15
89 INT95787 Positive_regulation of Mapk1 24 568 0.70 226.51 220.94
90 INT6665 Gene_expression of FOS 22 520 0.77 165.31 217.66
91 INT1308 Localization of Pomc 10 457 0.81 66.83 217.5
92 INT6293 Gene_expression of Oprm1 13 312 0.78 48.73 215.61
93 INT6481 Binding of TNF 16 624 0.48 510.2 214.82
94 INT767 Localization of Gnrhr 6 565 0.80 106.68 214.57
95 INT4893 Gene_expression of Tacr1 18 366 0.78 129.67 213.92
96 INT22548 Positive_regulation of Casp3 16 483 0.70 258.78 213.07
97 INT6482 Positive_regulation of Gene_expression of TNF 10 659 0.70 569.88 210
98 INT16259 Positive_regulation of Bdnf 6 336 0.70 183.48 209.82
99 INT48955 Gene_expression of Nos2 42 753 0.78 403.87 208.08
100 INT2651 Positive_regulation of Pomc 10 403 0.70 95.72 206.24
101 INT2391 Negative_regulation of PTGS1 20 501 0.59 207.62 205.6
102 INT9132 Negative_regulation of Prkcg 7 279 0.59 88.05 203.47
103 INT798 Positive_regulation of Gene_expression of Penk 16 394 0.70 78.53 203.07
104 INT11313 Positive_regulation of Il6 38 526 0.70 331.27 201.59
105 INT2211 Negative_regulation of Abat 12 267 0.59 66.51 200.98
106 INT50670 Gene_expression of CPOX 51 763 0.76 442.13 195.02
107 INT156 Negative_regulation of Prl 8 542 0.59 131.97 192.24
108 INT528 Gene_expression of Prl 12 693 0.78 217.18 192.2
109 INT6488 Gene_expression of Tnf 29 484 0.78 339.61 191.58
110 INT2085 Positive_regulation of LH 6 441 0.70 60.15 191.02
111 INT63934 Phosphorylation of Ephb1 3 377 0.82 150.52 188.66
112 INT6354 Localization of Gabrg1 4 321 0.74 41.41 186.74
113 INT94952 Positive_regulation of Mapk14 9 305 0.70 197.83 186.61
114 INT1652 Regulation of Pomc 6 387 0.62 61.01 186.51
115 INT24326 Gene_expression of Ngf 15 346 0.78 218.67 184.71
116 INT10194 Positive_regulation of IL6 22 702 0.70 600.62 183.38
117 INT4803 Transcription of Penk 15 435 0.72 59.09 182.4
118 INT3440 Negative_regulation of Localization of Abat 11 221 0.57 33.94 180.36
119 INT12602 Negative_regulation of Oprm1 15 190 0.59 36.11 177.85
120 INT49441 Negative_regulation of Cpox 20 494 0.59 303.22 177.46
121 INT7506 Negative_regulation of Ltp 3 267 0.46 91.01 176.8
122 INT1429 Gene_expression of PDYN 10 308 0.78 61.33 175.65
123 INT19472 Gene_expression of Il1 6 554 0.76 419.75 175.35
124 INT943 Negative_regulation of Cck 7 205 0.59 38.42 174.78
125 INT26472 Regulation of Oprm1 7 191 0.62 35.84 173.1
126 INT15516 Gene_expression of Crp 38 711 0.77 615.33 173.09
127 INT5930 Positive_regulation of Oprm1 15 221 0.70 31.19 172.93
128 INT159 Negative_regulation of Localization of Prl 7 416 0.59 55.34 171.8
129 INT4937 Negative_regulation of Oprd1 7 224 0.59 44.51 171.11
130 INT438 Gene_expression of Crh 22 376 0.78 159.11 169.17
131 INT867 Gene_expression of IFNA1 25 930 0.78 594.85 168.03
132 INT739 Negative_regulation of POMC 9 358 0.59 102.28 166.77
133 INT55879 Gene_expression of CCL2 13 421 0.78 240.74 166.02
134 INT1114 Localization of Ins1 5 748 0.80 192.95 165.48
135 INT4768 Positive_regulation of OPRM1 10 212 0.70 31.09 164.28
136 INT2366 Binding of Cck 2 192 0.48 30.64 163.46
137 INT5127 Localization of Lhb 6 488 0.80 50.48 162.66
138 INT3448 Positive_regulation of Gh 12 521 0.69 180.03 161.18
139 INT5513 Negative_regulation of Pomc 5 295 0.59 60.9 158.63
140 INT51921 Gene_expression of Cpox 54 501 0.73 229.81 157.81
141 INT21185 Binding of Ptprg 15 213 0.47 13.49 157.75
142 INT66280 Gene_expression of Nos2 3 534 0.78 330.78 157.07
143 INT768 Positive_regulation of Oprl1 12 179 0.70 40.05 156.93
144 INT1303 Negative_regulation of Npr1 6 278 0.55 35.1 156.78
145 INT2640 Gene_expression of Pomc 1 424 0.78 120.72 155.37
146 INT6042 Binding of Oprm1 13 248 0.48 31.77 154.34
147 INT4740 Gene_expression of Th 9 298 0.78 61.27 154.03
148 INT2910 Regulation of Abat 9 169 0.62 36.95 153.53
149 INT1044 Negative_regulation of Localization of LH 5 358 0.59 25.95 151.31
150 INT120811 Gene_expression of Gopc 7 1174 0.59 428.49 150.55
151 INT4829 Positive_regulation of Localization of Abat 6 199 0.55 20.91 150.48
152 INT880 Positive_regulation of Localization of Gh1 5 304 0.70 14.79 150.23
153 INT15515 Positive_regulation of Crp 45 700 0.70 604.24 150.15
154 INT49134 Gene_expression of Grin1 11 270 0.78 84.78 148.61
155 INT5050 Regulation of Localization of Calca 7 149 0.62 41.25 148.57
156 INT6108 Gene_expression of Npy 8 292 0.78 110.65 148.21
157 INT13353 Positive_regulation of Tnf 25 332 0.70 248.75 148.1
158 INT1033 Positive_regulation of Ca2 3 507 0.68 131.76 147.64
159 INT9852 Positive_regulation of Gpt 10 563 0.70 364.64 146.82
160 INT5116 Gene_expression of IL2 16 670 0.78 291.13 146.69
161 INT812 Localization of INS 18 1026 0.81 515.6 145.31
162 INT425 Localization of PRL 1 455 0.81 189.64 144.8
163 INT2379 Positive_regulation of Localization of LH 3 349 0.70 27.86 144.53
164 INT3300 Positive_regulation of Gene_expression of Calca 12 179 0.70 77.76 144.2
165 INT2780 Regulation of Gene_expression of Penk 14 265 0.62 32.45 143.88
166 INT60694 Gene_expression of Il10 11 567 0.78 369.48 143.69
167 INT9660 Regulation of TNF 10 363 0.62 312.94 139.99
168 INT1414 Regulation of Oprl1 5 169 0.62 32.05 139.99
169 INT90910 Phosphorylation of Grin1 5 150 0.82 68.23 139.24
170 INT14843 Gene_expression of Gabrg1 4 301 0.77 62.63 139.16
171 INT1273 Gene_expression of Avp 6 356 0.78 90.56 138.7
172 INT48895 Gene_expression of Il10 14 333 0.78 221.2 138.52
173 INT2867 Gene_expression of CALCA 23 247 0.78 78.78 138.47
174 INT4658 Binding of OPRM1 5 188 0.48 25.96 136.24
175 INT1047 Negative_regulation of LH 8 314 0.59 53.71 135.89
176 INT2541 Binding of Calca 12 200 0.48 67.14 134.62
177 INT60126 Regulation of Trpv1 11 186 0.62 85.53 133.4
178 INT11012 Positive_regulation of Creb1 20 258 0.70 84.4 132
179 INT48953 Positive_regulation of Nos2 26 486 0.70 239.85 131.87
180 INT5497 Positive_regulation of Crh 12 299 0.70 125.54 131.14
181 INT5380 Positive_regulation of Gene_expression of Fos 4 243 0.70 105.65 131.05
182 INT49439 Gene_expression of Cpox 15 508 0.73 326.97 130.17
183 INT5595 Positive_regulation of Pdyn 14 223 0.70 48.37 130.14
184 INT64161 Positive_regulation of Prkca 4 213 0.70 85.06 129.91
185 INT115386 Gene_expression of Ppara 4 779 0.77 549.99 128.36
186 INT65600 Positive_regulation of Casp3 13 376 0.70 198.44 128.03
187 INT1614 Gene_expression of Oprl1 12 164 0.78 31.43 127.74
188 INT5842 Gene_expression of Gfap 8 372 0.78 153.71 127.71
189 INT1878 Binding of HLA-B 20 440 0.48 321.16 127.36
190 INT695 Binding of POMC 3 304 0.48 56.66 126.85
191 INT65054 Positive_regulation of Nfkb1 30 285 0.70 149.33 126.73
192 INT5931 Regulation of Oprm1 10 149 0.62 18.15 125.93
193 INT6822 Gene_expression of Pdyn 7 215 0.78 35.99 125.76
194 INT416 Regulation of LH 5 253 0.62 31.48 125.55
195 INT5008 Localization of Calca 4 204 0.81 80.35 125.16
196 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
197 INT4824 Positive_regulation of Tacr1 18 169 0.70 66.1 123.46
198 INT4259 Positive_regulation of Npr1 4 262 0.70 49.37 123.11
199 INT2106 Regulation of Localization of LH 5 279 0.62 22.37 122.77
200 INT252 Localization of GH1 13 529 0.80 227.4 122.05
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