Y:2007

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 2007. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 2007. They are ordered first by their pain relevance and then by number of times they were reported in 2007. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 2007 Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 3 0.54 8.87 18.3
2 INT145775 Ngf Positive_regulation of Trpv1 11 1 0.72 7.71 11.25
3 INT206768 TP53 Positive_regulation of Ltp 2 1 0.01 5.83 10.21
4 INT149117 Binding of CD80 and CTLA4 31 5 0.52 12.7 7.73
5 INT106559 Binding of Bdnf and Ntrk2 23 2 0.43 11.09 7.33
6 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 2 0.76 8.19 6.66
7 INT140015 Avp Positive_regulation of Localization of Penk 3 2 0.63 3.48 6.63
8 INT131249 Binding of Bdnf and Ntrk2 11 4 0.41 4 6.25
9 INT84921 Binding of NGF and NTRK1 13 1 0.50 6.39 6.1
10 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 1 0.74 4.31 6.1
11 INT176477 Binding of CXCR3 and CXCL10 14 2 0.25 10.61 5.87
12 INT179502 Binding of Cd14 and Tlr4 29 3 0.39 13.77 5.73
13 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 8 0.78 3.57 5.71
14 INT140935 Binding of Cd40lg and Cd40 1 6 0.30 6.34 5.61
15 INT211710 Binding of Mc1r and a 7 4 0.44 0.37 4.78
16 INT182124 Binding of IRF6 and TLR4 14 2 0.10 16.11 4.65
17 INT139706 Tnf Positive_regulation of Ltp 1 4 0.03 2.61 4.63
18 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 1 0.59 9.37 4.48
19 INT143270 Binding of Cnr1 and Gprasp1 4 2 0.54 0.64 4.18
20 INT182194 Binding of IL8 and CXCR2 10 1 0.56 7.14 4.16
21 INT29240 Binding of POMC and YY1 5 1 0.40 0.17 4.06
22 INT127128 Binding of CNR1 and CNR2 8 1 0.39 3.98 3.97
23 INT61359 TNF Positive_regulation of NFKB1 11 2 0.63 6.66 3.89
24 INT143946 Binding of Pebp1 and Mastl 1 4 0.00 2.04 3.82
25 INT220623 Binding of Stat1 and Bace1 11 6 0.25 10.33 3.81
26 INT122349 Ngf Regulation of Trpv1 3 1 0.64 1.55 3.79
27 INT141254 Ngf Regulation of Transcription of Trpv1 1 3 0.53 1.37 3.74
28 INT132862 Ngf Positive_regulation of Bdnf 4 1 0.46 4.05 3.65
29 INT180984 IRF6 Positive_regulation of Localization of IL8 7 1 0.11 2.13 3.47
30 INT212658 KCNA1 Positive_regulation of Cort 1 4 0.00 2.58 3.36
31 INT215943 Binding of Mmp14 and Timp2 1 4 0.21 1.59 3.33
32 INT194647 Binding of CD28 and CD80 15 6 0.40 4.9 3.22
33 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 2 0.66 5.22 3.22
34 INT166134 Binding of Cxcl12 and Cxcr4 3 1 0.49 5.69 3.17
35 INT211694 Binding of Cntnap1 and Nav1 1 4 0.04 0 3.14
36 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 3 0.35 13.11 3.11
37 INT1151 Binding of CCK and GAST 7 1 0.49 0.73 3.08
38 INT208572 Binding of IL8 and CXCR1 6 2 0.33 5.2 3.08
39 INT102284 Binding of Grin1 and Grin2a 5 1 0.27 1.79 3.01
40 INT106837 Binding of Oprm1 and Arrb2 3 1 0.32 0.83 3.01
41 INT152699 Bdnf Positive_regulation of Ltp 5 3 0.05 1.22 2.95
42 INT221746 Ngf Positive_regulation of Ntrk1 1 2 0.02 0.92 2.88
43 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 1 0.06 2.01 2.85
44 INT206764 Binding of AQP4 and Nqo1 8 2 0.05 13.45 2.84
45 INT175329 Binding of ICAM1 and ITGAL 14 2 0.18 10.06 2.81
46 INT220062 Binding of NGF and TNFRSF1B 1 2 0.10 2.21 2.81
47 INT83169 Binding of Cck and Lep 7 1 0.42 1.58 2.78
48 INT140347 Binding of ATP1A2 and Cacna1a 1 2 0.11 2.88 2.73
49 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 4 0.49 0.67 2.69
50 INT220061 Binding of TRPV1 and TRPA1 1 2 0.15 1.7 2.69
51 INT212505 Binding of pr and Lbp 1 5 0.01 4.26 2.62
52 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 2 0.46 0.75 2.61
53 INT210696 Trpv1 Regulation of Slc12a2 1 2 0.25 1.97 2.58
54 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 2 0.78 0.16 2.53
55 INT147659 Prkce Positive_regulation of TRPV1 1 2 0.04 1.42 2.43
56 INT143272 Binding of CNR1 and Gprasp1 1 2 0.01 0.17 2.42
57 INT122163 Binding of TNF and TNFRSF1B 6 1 0.44 6.06 2.41
58 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 1 0.09 2.6 2.4
59 INT214144 Cck Positive_regulation of Pomc 1 3 0.15 0.94 2.39
60 INT115367 Binding of IL6 and IL6R 12 1 0.07 8.16 2.36
61 INT74840 Binding of Cacna1a and Cacna1a 5 1 0.00 4.24 2.36
62 INT214159 Cck Positive_regulation of Nts 1 3 0.03 0.93 2.34
63 INT139723 PROC Positive_regulation of MAPK8 1 2 0.01 2.98 2.33
64 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 2 0.03 1.19 2.3
65 INT103548 Binding of TRPV1 and TRPV3 3 2 0.37 1.82 2.28
66 INT106558 Binding of Ntrk2 and Ntrk3 3 1 0.52 2.51 2.28
67 INT211748 Binding of Pag1 and Mors1 2 1 0.07 0.2 2.26
68 INT275398 Binding of ITIH4 and Htatsf1 1 4 0.02 5.05 2.24
69 INT194646 Binding of CD28 and CD86 7 3 0.40 2.69 2.21
70 INT197379 Tbs1 Positive_regulation of Ltp 6 3 0.07 1.87 2.21
71 INT146930 CAP1 Regulation of ABCB1 1 2 0.29 0.3 2.19
72 INT140659 Phax Positive_regulation of Trpv1 3 1 0.49 0.68 2.18
73 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 2 0.69 0.5 2.18
74 INT86179 TNF Positive_regulation of Localization of IL6 5 1 0.35 1.66 2.17
75 INT209924 IL1B Negative_regulation of PPARA 1 15 0.20 4.38 2.17
76 INT49242 Binding of Mc1r and Pomc 10 4 0.38 3.79 2.15
77 INT229394 TPSD1 Positive_regulation of F2RL1 2 3 0.00 3.11 2.14
78 INT142527 Binding of Slc1a2 and Slc1a3 2 1 0.31 0.12 2.13
79 INT212301 NGF Regulation of Gene_expression of TRPV1 1 2 0.23 2.37 2.13
80 INT148704 Binding of TNF and TNFRSF1A 5 3 0.44 3.3 2.09
81 INT122660 Binding of CACNA1A and DNAH8 2 1 0.28 2.68 2.08
82 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 1 0.41 0 2.01
83 INT189999 Binding of Vta1 and Cfp 2 2 0.08 1.25 1.97
84 INT157767 Binding of TLR4 and LY96 8 1 0.54 4.05 1.95
85 INT217042 IRF6 Positive_regulation of TNF 4 1 0.27 3.03 1.95
86 INT146099 Binding of Oprm1 and Rgs9 1 2 0.48 0 1.95
87 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 2 0.05 0.18 1.92
88 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 2 0.06 0.18 1.92
89 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 1 0.08 1.33 1.89
90 INT183781 Binding of IL6 and INS 6 1 0.22 8.97 1.87
91 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 2 0.09 0 1.86
92 INT205152 Binding of CD44 and MMP9 23 21 0.35 17.13 1.85
93 INT207630 Binding of Calm3 and Nrgn 1 13 0.06 1.03 1.82
94 INT192161 Mmp14 Positive_regulation of Mmp2 2 1 0.19 1.23 1.81
95 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 10 0.13 5.83 1.8
96 INT100771 Binding of Itga1 and Vcam1 3 2 0.11 3.91 1.79
97 INT66504 Binding of Agt and Agtr1a 8 6 0.39 3.78 1.78
98 INT145940 Binding of Gad1 and Abat 2 1 0.14 1.44 1.78
99 INT211746 Binding of Oprm1 and Mors1 1 2 0.08 0 1.78
100 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 1 0.23 0 1.76
101 INT266764 TPSD1 Positive_regulation of F2RL1 Positive_regulation of Localization of SFTPA1 1 1 0.00 1.55 1.76
102 INT140892 Penk Negative_regulation of Mnp 1 1 0.13 0.55 1.75
103 INT139640 Jun Regulation of Gene_expression of Npy 1 2 0.21 1.98 1.75
104 INT204552 Sult2a2 Regulation of Cia1 1 2 0.01 2.75 1.75
105 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 1 0.01 1.07 1.75
106 INT142073 Binding of Helt and Nrm 1 2 0.00 0 1.74
107 INT139156 Binding of Gria1 and Gria2 1 1 0.23 0.64 1.72
108 INT139190 Binding of Fadd and Fas 4 3 0.38 2.65 1.71
109 INT137207 Tnf Positive_regulation of Nfkb1 3 1 0.23 2.69 1.71
110 INT215100 Binding of Hmgb1 and Tlr4 5 5 0.29 3.21 1.68
111 INT145098 NGF Positive_regulation of BDNF 1 1 0.66 1.33 1.67
112 INT142437 Urb1 Negative_regulation of Faah 3 1 0.41 2.12 1.66
113 INT144213 Nppa Positive_regulation of Localization of Calca 1 3 0.71 2.8 1.65
114 INT147258 Binding of Tac1 and Penk 1 2 0.35 0 1.64
115 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 2 0.47 1.01 1.63
116 INT147654 DYT10 Negative_regulation of Positive_regulation of TRPV1 1 1 0.27 0.93 1.62
117 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 1 0.27 0.92 1.62
118 INT215096 Binding of Hmgb1 and Tlr2 9 3 0.38 11.61 1.61
119 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 2 0.08 4.21 1.61
120 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 1 0.01 1.65 1.6
121 INT209853 TNF Regulation of Gene_expression of CD36 1 6 0.61 3.41 1.59
122 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 1 0.02 0.33 1.59
123 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 1 0.01 1.69 1.59
124 INT141907 F2r Regulation of Plat 1 1 0.46 0 1.59
125 INT136034 Edn1 Regulation of Trpv1 2 2 0.66 0.39 1.58
126 INT212287 ro Negative_regulation of Ltp 1 3 0.00 1.2 1.58
127 INT212660 Nr3c1 Regulation of KCNA1 1 2 0.00 1.25 1.57
128 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 2 0.37 0.78 1.56
129 INT208991 Binding of CALM1 and Ca2 10 4 0.06 1.34 1.55
130 INT74937 IL1B Positive_regulation of CPOX 5 1 0.18 1.13 1.55
131 INT208980 Binding of Ca2 and Trpv1 4 3 0.32 0.67 1.55
132 INT74843 Binding of Cacna1a and Ea2 3 1 0.13 3.29 1.55
133 INT209087 Crh Positive_regulation of Ceacam3 1 1 0.24 1.45 1.54
134 INT241750 Binding of CD4 and ITIH4 14 1 0.18 5.72 1.53
135 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 1 0.17 3.36 1.53
136 INT145072 ASIP Negative_regulation of MC1R 1 2 0.29 0 1.52
137 INT222335 Binding of Bdnf and Ngfr 3 2 0.05 2.66 1.48
138 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 1 0.12 1.31 1.48
139 INT211744 Binding of Gopc and Mors1 1 1 0.10 0.2 1.48
140 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 1 0.11 1.31 1.48
141 INT140332 RPL7AP5 Negative_regulation of Ltp 1 1 0.00 0.64 1.47
142 INT144452 Binding of GPM6A and GPM6B 1 2 0.28 0 1.46
143 INT140329 Grin1 Negative_regulation of Ltp 1 1 0.04 0.64 1.46
144 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 1 0.13 0 1.46
145 INT141676 OPRM1 Positive_regulation of Ltp 1 1 0.04 0 1.46
146 INT141674 Oprm1 Positive_regulation of Ltp 1 1 0.13 0 1.46
147 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 1 0.04 0 1.46
148 INT144454 Binding of DMPK and GPM6A 1 2 0.00 0 1.45
149 INT221242 Ros1 Positive_regulation of Prkca 1 3 0.02 0.39 1.44
150 INT266771 Binding of NGF and GOPC 1 2 0.05 3.23 1.43
151 INT214372 Ptprq Positive_regulation of Akt1 1 2 0.04 0.88 1.43
152 INT150069 Cnr1 Regulation of Cnr2 2 1 0.50 0.83 1.42
153 INT224404 Binding of GYPC and PYY 1 3 0.04 1.48 1.42
154 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 2 0.07 1.35 1.41
155 INT142852 Oprm1 Positive_regulation of Oprd1 1 1 0.41 0.06 1.41
156 INT214369 Pik3cb Positive_regulation of Akt1 1 2 0.56 0.87 1.41
157 INT144122 Binding of Calca and P2rx6 1 4 0.10 0 1.4
158 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 2 0.04 1.35 1.4
159 INT142490 Avp Regulation of Oxt 1 1 0.09 0.74 1.4
160 INT140314 PCSK7 Positive_regulation of LDHA 1 2 0.07 1.6 1.4
161 INT144123 Binding of P2rx6 and Trpv1 1 4 0.11 0 1.4
162 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 1 0.08 1.11 1.39
163 INT138099 Binding of Grin2a and Insrr 1 1 0.01 0.36 1.39
164 INT108727 Binding of ATP1A2 and CACNA1A 2 1 0.34 1.97 1.37
165 INT212662 KCNA1 Regulation of Localization of Cort 1 2 0.00 1.36 1.37
166 INT261483 Binding of Ephb1 and Trpv1 1 2 0.39 1.37 1.37
167 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 1 0.16 0.17 1.35
168 INT261463 Binding of Drd1a and Sftpd 1 3 0.12 0.13 1.35
169 INT106839 Arrb2 Regulation of Oprm1 2 1 0.21 0.44 1.33
170 INT145473 Mastl Positive_regulation of Dnahc8 1 3 0.07 0.06 1.33
171 INT143999 IK Regulation of Gene_expression of Penk 1 2 0.04 0 1.33
172 INT209409 Binding of CALM1 and NHS 2 4 0.27 0.58 1.32
173 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 1 0.49 1.2 1.3
174 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 5 0.07 0 1.3
175 INT186393 Binding of TNF and Tnfrsf1a 9 6 0.37 8.55 1.29
176 INT107858 PRSS1 Positive_regulation of F2RL1 6 2 0.12 4.23 1.29
177 INT95406 Trib3 Positive_regulation of Ephb1 2 1 0.08 0.96 1.29
178 INT208990 Binding of CALM1 and Trpv1 1 3 0.10 0.07 1.29
179 INT147653 TACR1 Positive_regulation of TRPV1 1 1 0.02 0.72 1.29
180 INT139722 PROC Positive_regulation of CDCP1 1 1 0.00 1.61 1.29
181 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 1 0.49 1.14 1.27
182 INT74841 Binding of Cacna1a and Ea2 2 1 0.01 2.33 1.27
183 INT70226 Binding of TAC1 and B3GAT1 4 2 0.24 4.5 1.26
184 INT142431 Cp Positive_regulation of Crh 1 2 0.31 1.49 1.26
185 INT143620 Ltp Positive_regulation of Npr1 1 1 0.01 0.16 1.26
186 INT219686 Binding of CEL and COPD 1 4 0.12 11.35 1.26
187 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 3 0.01 0.46 1.26
188 INT211743 Positive_regulation of Binding of Pag1 and Mors1 1 1 0.09 0.1 1.25
189 INT139724 PROC Positive_regulation of MAPK14 1 1 0.00 1.57 1.25
190 INT66205 TNF Positive_regulation of TNF Positive_regulation of NFKB1 4 1 0.41 2.74 1.24
191 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 1 0.05 0 1.24
192 INT145315 D2Mit212 Regulation of Casp3 1 1 0.00 0 1.24
193 INT141244 Fos Regulation of Prkaca 1 1 0.18 0.07 1.24
194 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 1 0.00 0 1.24
195 INT147033 Positive_regulation of Binding of Sds and Accn3 1 1 0.13 0.73 1.23
196 INT145317 D2Mit212 Positive_regulation of Casp3 1 1 0.01 0 1.22
197 INT139191 Binding of Fas and RFFL 1 2 0.00 0.61 1.22
198 INT197231 Grik1 Regulation of Gabrg1 1 1 0.19 0.13 1.22
199 INT147032 Binding of Sds and Accn3 1 1 0.09 0.73 1.22
200 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 2 0.22 0 1.21

Single Events

The table below shows the top 100 pain related interactions that have been reported in 2007. They are ordered first by their pain relevance and then by number of times they were reported in 2007. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 2007 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 191 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 87 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 69 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 22 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 506 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 198 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 65 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 42 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 72 1163 0.70 319.28 684
10 INT292 Localization of Penk 11 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 105 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 25 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 54 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 17 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 34 934 0.70 209.8 503.87
16 INT155 Positive_regulation of Prl 44 1233 0.70 317.93 457.82
17 INT1045 Localization of LH 1 1211 0.81 87.04 456.25
18 INT443 Localization of POMC 18 1020 0.81 284.52 443.17
19 INT50058 Negative_regulation of Cpox 67 907 0.58 426.28 428.29
20 INT9238 Gene_expression of IL6 174 1575 0.78 1135.66 424.22
21 INT4758 Positive_regulation of Localization of Calca 36 557 0.70 138.55 411.04
22 INT5895 Gene_expression of Oprm1 80 525 0.78 120.67 407.29
23 INT64202 Positive_regulation of Trpv1 75 643 0.70 249.66 397.42
24 INT467 Gene_expression of POMC 22 1048 0.78 332.8 394.16
25 INT1395 Negative_regulation of Penk 8 537 0.59 87.33 389.81
26 INT6056 Negative_regulation of Gene_expression of Fos 39 601 0.59 193.05 386.84
27 INT76660 Gene_expression of Trpv1 44 691 0.78 329.46 386.42
28 INT2540 Negative_regulation of Calca 23 538 0.59 172.11 384.38
29 INT18357 Gene_expression of TRPV1 158 825 0.78 307.11 382.81
30 INT6580 Negative_regulation of Ptgs1 48 929 0.59 381.53 376.26
31 INT157 Positive_regulation of Localization of Prl 3 790 0.70 104.54 374.78
32 INT287 Localization of Cck 16 518 0.81 86.84 364.04
33 INT439 Localization of Gnrh1 3 976 0.81 100.96 363.25
34 INT720 Positive_regulation of POMC 29 807 0.70 237.37 353.83
35 INT5660 Binding of Oprd1 19 477 0.48 71.86 342.06
36 INT876 Localization of Gh1 6 843 0.80 67.75 340.82
37 INT16260 Gene_expression of Bdnf 99 671 0.78 283.44 339.1
38 INT5235 Negative_regulation of TNF 121 924 0.59 772.91 331.98
39 INT2649 Regulation of Calca 17 433 0.62 146.05 330.95
40 INT5059 Positive_regulation of TNF 155 1050 0.70 896.51 322.81
41 INT162 Regulation of Prl 14 794 0.62 165.01 322.24
42 INT5979 Gene_expression of Oprd1 17 428 0.78 75.64 320.32
43 INT34869 Negative_regulation of PTGS2 67 778 0.59 366.76 319.85
44 INT5540 Positive_regulation of Oprm1 40 344 0.70 76.77 319.71
45 INT5680 Gene_expression of Ngf 57 530 0.78 264.29 310.56
46 INT46460 Gene_expression of NAV1 44 288 0.78 135.51 305.75
47 INT4941 Positive_regulation of Oprd1 13 345 0.70 74.26 304.41
48 INT9131 Positive_regulation of Prkcg 51 431 0.70 130.8 302.41
49 INT477 Localization of Avp 13 813 0.81 131.58 300.4
50 INT161 Regulation of Localization of Prl 5 615 0.62 65.37 298.66
51 INT63932 Positive_regulation of Ephb1 105 537 0.70 259.67 296.14
52 INT1352 Localization of Acot1 26 728 0.80 73.01 296.01
53 INT886 Gene_expression of Pomc 17 676 0.78 129.87 295.98
54 INT11624 Gene_expression of OPRM1 15 445 0.78 72.36 294.36
55 INT5379 Gene_expression of Fos 57 656 0.78 255.5 292.54
56 INT3579 Localization of Oxt 36 555 0.81 43.35 292.44
57 INT97367 Gene_expression of Nav1 43 243 0.78 132.97 286.66
58 INT9158 Gene_expression of Tnf 64 722 0.78 522.01 277.68
59 INT2365 Positive_regulation of Cck 14 354 0.70 87.8 277.41
60 INT9381 Positive_regulation of TRPV1 106 523 0.70 187.4 276.05
61 INT94450 Gene_expression of Nav1 30 359 0.78 131.85 275.46
62 INT49750 Negative_regulation of CPOX 95 735 0.58 360.06 274.19
63 INT6852 Localization of TNF 117 883 0.81 705.95 270.84
64 INT10832 Gene_expression of IL8 122 1050 0.78 698.72 270
65 INT1396 Binding of Penk 5 355 0.48 22.79 269.65
66 INT5591 Regulation of Gene_expression of Fos 28 425 0.62 129.06 265.78
67 INT9659 Gene_expression of Il6 99 991 0.78 715.11 265.57
68 INT5972 Gene_expression of IL1B 133 948 0.78 510.91 263.97
69 INT68684 Gene_expression of VEGFA 339 2371 0.78 1742.52 259.2
70 INT87687 Positive_regulation of Trpv1 32 409 0.70 210.24 257.59
71 INT1893 Localization of Gh 55 1041 0.79 340.23 256.58
72 INT16868 Gene_expression of Il6 42 807 0.78 499.48 256.57
73 INT2909 Positive_regulation of Abat 21 334 0.70 62.1 256.43
74 INT3948 Regulation of Cck 13 291 0.62 58.07 255.88
75 INT5501 Regulation of Oprd1 15 283 0.62 55.1 249.9
76 INT738 Regulation of POMC 4 459 0.62 111.19 243.74
77 INT1902 Gene_expression of Cck 9 348 0.78 70.33 241.92
78 INT11377 Positive_regulation of Ngf 25 331 0.70 206.5 238
79 INT1562 Localization of Crh 11 499 0.81 126.74 236.68
80 INT5597 Gene_expression of Pdyn 25 433 0.78 62.97 235.47
81 INT1665 Positive_regulation of Pag1 12 270 0.68 186.63 229.87
82 INT4759 Negative_regulation of Localization of Calca 12 294 0.59 82.62 226.45
83 INT9987 Gene_expression of Abat 28 296 0.78 95.46 226.34
84 INT6406 Binding of Oprm1 25 280 0.48 40.54 226.26
85 INT1212 Binding of Oprl1 3 312 0.48 28.6 225.15
86 INT11009 Phosphorylation of Creb1 35 458 0.82 111.34 221.97
87 INT626 Localization of CALCA 30 289 0.81 125.39 221.15
88 INT95787 Positive_regulation of Mapk1 63 568 0.70 226.51 220.94
89 INT6665 Gene_expression of FOS 27 520 0.77 165.31 217.66
90 INT1308 Localization of Pomc 4 457 0.81 66.83 217.5
91 INT6293 Gene_expression of Oprm1 12 312 0.78 48.73 215.61
92 INT6481 Binding of TNF 105 624 0.48 510.2 214.82
93 INT767 Localization of Gnrhr 7 565 0.80 106.68 214.57
94 INT4893 Gene_expression of Tacr1 87 366 0.78 129.67 213.92
95 INT22548 Positive_regulation of Casp3 58 483 0.70 258.78 213.07
96 INT6482 Positive_regulation of Gene_expression of TNF 97 659 0.70 569.88 210
97 INT16259 Positive_regulation of Bdnf 43 336 0.70 183.48 209.82
98 INT48955 Gene_expression of Nos2 82 753 0.78 403.87 208.08
99 INT2651 Positive_regulation of Pomc 12 403 0.70 95.72 206.24
100 INT2391 Negative_regulation of PTGS1 28 501 0.59 207.62 205.6
101 INT9132 Negative_regulation of Prkcg 39 279 0.59 88.05 203.47
102 INT798 Positive_regulation of Gene_expression of Penk 28 394 0.70 78.53 203.07
103 INT11313 Positive_regulation of Il6 35 526 0.70 331.27 201.59
104 INT2211 Negative_regulation of Abat 16 267 0.59 66.51 200.98
105 INT50670 Gene_expression of CPOX 108 763 0.76 442.13 195.02
106 INT156 Negative_regulation of Prl 4 542 0.59 131.97 192.24
107 INT528 Gene_expression of Prl 21 693 0.78 217.18 192.2
108 INT6488 Gene_expression of Tnf 51 484 0.78 339.61 191.58
109 INT63934 Phosphorylation of Ephb1 95 377 0.82 150.52 188.66
110 INT6354 Localization of Gabrg1 22 321 0.74 41.41 186.74
111 INT94952 Positive_regulation of Mapk14 54 305 0.70 197.83 186.61
112 INT1652 Regulation of Pomc 3 387 0.62 61.01 186.51
113 INT24326 Gene_expression of Ngf 13 346 0.78 218.67 184.71
114 INT10194 Positive_regulation of IL6 92 702 0.70 600.62 183.38
115 INT4803 Transcription of Penk 18 435 0.72 59.09 182.4
116 INT3440 Negative_regulation of Localization of Abat 13 221 0.57 33.94 180.36
117 INT12602 Negative_regulation of Oprm1 17 190 0.59 36.11 177.85
118 INT49441 Negative_regulation of Cpox 89 494 0.59 303.22 177.46
119 INT7506 Negative_regulation of Ltp 55 267 0.46 91.01 176.8
120 INT1429 Gene_expression of PDYN 9 308 0.78 61.33 175.65
121 INT19472 Gene_expression of Il1 69 554 0.76 419.75 175.35
122 INT943 Negative_regulation of Cck 3 205 0.59 38.42 174.78
123 INT26472 Regulation of Oprm1 20 191 0.62 35.84 173.1
124 INT15516 Gene_expression of Crp 73 711 0.77 615.33 173.09
125 INT5930 Positive_regulation of Oprm1 4 221 0.70 31.19 172.93
126 INT159 Negative_regulation of Localization of Prl 3 416 0.59 55.34 171.8
127 INT4937 Negative_regulation of Oprd1 8 224 0.59 44.51 171.11
128 INT438 Gene_expression of Crh 33 376 0.78 159.11 169.17
129 INT867 Gene_expression of IFNA1 47 930 0.78 594.85 168.03
130 INT739 Negative_regulation of POMC 4 358 0.59 102.28 166.77
131 INT55879 Gene_expression of CCL2 36 421 0.78 240.74 166.02
132 INT1114 Localization of Ins1 45 748 0.80 192.95 165.48
133 INT4768 Positive_regulation of OPRM1 7 212 0.70 31.09 164.28
134 INT2366 Binding of Cck 8 192 0.48 30.64 163.46
135 INT5127 Localization of Lhb 37 488 0.80 50.48 162.66
136 INT3448 Positive_regulation of Gh 21 521 0.69 180.03 161.18
137 INT5513 Negative_regulation of Pomc 1 295 0.59 60.9 158.63
138 INT51921 Gene_expression of Cpox 37 501 0.73 229.81 157.81
139 INT66280 Gene_expression of Nos2 89 534 0.78 330.78 157.07
140 INT768 Positive_regulation of Oprl1 10 179 0.70 40.05 156.93
141 INT1303 Negative_regulation of Npr1 9 278 0.55 35.1 156.78
142 INT2640 Gene_expression of Pomc 89 424 0.78 120.72 155.37
143 INT6042 Binding of Oprm1 11 248 0.48 31.77 154.34
144 INT4740 Gene_expression of Th 16 298 0.78 61.27 154.03
145 INT2910 Regulation of Abat 24 169 0.62 36.95 153.53
146 INT120811 Gene_expression of Gopc 113 1174 0.59 428.49 150.55
147 INT4829 Positive_regulation of Localization of Abat 8 199 0.55 20.91 150.48
148 INT880 Positive_regulation of Localization of Gh1 3 304 0.70 14.79 150.23
149 INT15515 Positive_regulation of Crp 74 700 0.70 604.24 150.15
150 INT49134 Gene_expression of Grin1 13 270 0.78 84.78 148.61
151 INT5050 Regulation of Localization of Calca 4 149 0.62 41.25 148.57
152 INT6108 Gene_expression of Npy 7 292 0.78 110.65 148.21
153 INT13353 Positive_regulation of Tnf 47 332 0.70 248.75 148.1
154 INT7628 Gene_expression of Ltp 45 273 0.77 70.21 147.87
155 INT2451 Positive_regulation of Avp 14 355 0.70 102.66 147.69
156 INT1033 Positive_regulation of Ca2 65 507 0.68 131.76 147.64
157 INT9852 Positive_regulation of Gpt 67 563 0.70 364.64 146.82
158 INT5116 Gene_expression of IL2 59 670 0.78 291.13 146.69
159 INT812 Localization of INS 148 1026 0.81 515.6 145.31
160 INT425 Localization of PRL 81 455 0.81 189.64 144.8
161 INT3300 Positive_regulation of Gene_expression of Calca 16 179 0.70 77.76 144.2
162 INT2780 Regulation of Gene_expression of Penk 8 265 0.62 32.45 143.88
163 INT60694 Gene_expression of Il10 74 567 0.78 369.48 143.69
164 INT9660 Regulation of TNF 52 363 0.62 312.94 139.99
165 INT1414 Regulation of Oprl1 9 169 0.62 32.05 139.99
166 INT90910 Phosphorylation of Grin1 12 150 0.82 68.23 139.24
167 INT14843 Gene_expression of Gabrg1 33 301 0.77 62.63 139.16
168 INT1273 Gene_expression of Avp 18 356 0.78 90.56 138.7
169 INT48895 Gene_expression of Il10 23 333 0.78 221.2 138.52
170 INT2867 Gene_expression of CALCA 18 247 0.78 78.78 138.47
171 INT5061 Negative_regulation of Mme 1 306 0.59 51.97 136.9
172 INT4658 Binding of OPRM1 8 188 0.48 25.96 136.24
173 INT1047 Negative_regulation of LH 4 314 0.59 53.71 135.89
174 INT2541 Binding of Calca 12 200 0.48 67.14 134.62
175 INT60126 Regulation of Trpv1 22 186 0.62 85.53 133.4
176 INT11012 Positive_regulation of Creb1 25 258 0.70 84.4 132
177 INT48953 Positive_regulation of Nos2 42 486 0.70 239.85 131.87
178 INT5497 Positive_regulation of Crh 27 299 0.70 125.54 131.14
179 INT5380 Positive_regulation of Gene_expression of Fos 21 243 0.70 105.65 131.05
180 INT49439 Gene_expression of Cpox 70 508 0.73 326.97 130.17
181 INT5595 Positive_regulation of Pdyn 3 223 0.70 48.37 130.14
182 INT64161 Positive_regulation of Prkca 25 213 0.70 85.06 129.91
183 INT115386 Gene_expression of Ppara 121 779 0.77 549.99 128.36
184 INT65600 Positive_regulation of Casp3 34 376 0.70 198.44 128.03
185 INT1614 Gene_expression of Oprl1 8 164 0.78 31.43 127.74
186 INT5842 Gene_expression of Gfap 32 372 0.78 153.71 127.71
187 INT1878 Binding of HLA-B 22 440 0.48 321.16 127.36
188 INT695 Binding of POMC 13 304 0.48 56.66 126.85
189 INT65054 Positive_regulation of Nfkb1 22 285 0.70 149.33 126.73
190 INT5931 Regulation of Oprm1 10 149 0.62 18.15 125.93
191 INT6822 Gene_expression of Pdyn 8 215 0.78 35.99 125.76
192 INT416 Regulation of LH 2 253 0.62 31.48 125.55
193 INT5008 Localization of Calca 21 204 0.81 80.35 125.16
194 INT6323 Positive_regulation of Gabrg1 21 213 0.70 45.08 124.34
195 INT4824 Positive_regulation of Tacr1 30 169 0.70 66.1 123.46
196 INT4259 Positive_regulation of Npr1 6 262 0.70 49.37 123.11
197 INT2106 Regulation of Localization of LH 1 279 0.62 22.37 122.77
198 INT252 Localization of GH1 35 529 0.80 227.4 122.05
199 INT6128 Positive_regulation of Localization of POMC 6 256 0.70 68.77 121.64
200 INT7533 Gene_expression of Tlr4 84 720 0.78 343.22 121.57
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