Y:2011

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 2011. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 2011. They are ordered first by their pain relevance and then by number of times they were reported in 2011. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 2011 Documents TM Confidence Disease Relevance Pain Relevance
1 INT356313 Crh Positive_regulation of Localization of Helt 1 4 0.02 0 2.11
2 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 1 0.01 0.06 1.86
3 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 1 0.04 0.06 1.86
4 INT353717 Binding of Ghrl and Vta1 1 2 0.15 0 1.68
5 INT355254 Ltp Regulation of Cacna1a 1 1 0.04 0 1.58
6 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 3 0.17 0 1.58
7 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 3 0.08 1.68 1.49
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 1 0.04 0 1.39
9 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 1 0.51 0 1.35
10 INT355253 Ltp Positive_regulation of Cacna1a 1 1 0.05 0 1.34
11 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 2 0.18 0.65 1.33
12 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 2 0.01 0.65 1.32
13 INT355252 Binding of Cacna1a and Cnr1 1 1 0.04 0 1.31
14 INT356316 Crh Positive_regulation of Localization of Cea 1 2 0.34 0 1.06
15 INT353741 Binding of IGHE and Aia1 1 2 0.00 1.16 1.06
16 INT154778 Cldn11 Positive_regulation of Eae1 4 1 0.12 3.24 1.03
17 INT336017 Vip Regulation of Tlr4 1 1 0.22 1.23 0.93
18 INT72917 Binding of Crh and Crhr1 4 1 0.32 0.73 0.91
19 INT120147 Tlr4 Positive_regulation of Tnf 3 1 0.39 2.14 0.89
20 INT354522 Binding of HBG2 and Wipi1 1 2 0.00 2.64 0.87
21 INT353719 Rbm39 Regulation of Localization of Vta1 1 1 0.01 0 0.84
22 INT340294 Ea1 Positive_regulation of Sirt1 1 2 0.06 0.53 0.83
23 INT237379 Binding of Ebi3 and Il27 2 2 0.05 1.71 0.82
24 INT339291 Casp1 Positive_regulation of Il1 2 1 0.12 1.63 0.8
25 INT295546 Ghrl Positive_regulation of Ghsr 3 1 0.39 0.09 0.77
26 INT355704 Binding of Cia1 and Aia1 1 1 0.00 1.85 0.77
27 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 1 0.16 0 0.76
28 INT353720 Binding of Drd1a and Ghsr 1 1 0.18 0 0.76
29 INT353718 Binding of Rbm39 and Ghsr 1 1 0.01 0 0.76
30 INT356324 ORF61 Regulation of Localization of Gabrg1 1 2 0.00 0.19 0.76
31 INT353630 Binding of Psmd1 and Shbdp1 1 2 0.02 0 0.76
32 INT353716 Ghrl Positive_regulation of Vta1 1 1 0.33 0 0.74
33 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 1 0.31 1.21 0.74
34 INT353722 Rbm39 Positive_regulation of Localization of Ghrl 1 1 0.01 0 0.65
35 INT340298 Ea1 Positive_regulation of Ppargc1a 1 1 0.05 1.03 0.64
36 INT356329 Crhr1 Regulation of Cea 1 1 0.09 0.31 0.64
37 INT356314 Binding of Crhr1 and ORF61 1 2 0.00 0 0.63
38 INT122096 Binding of HLA-B and SFTPA1 2 1 0.04 1.81 0.6
39 INT356328 Crh Positive_regulation of Cea 1 1 0.26 0.28 0.6
40 INT339967 Binding of Mog and Eae1 1 1 0.02 1.67 0.6
41 INT352496 AVP Regulation of Gene_expression of CRS 1 2 0.27 2.47 0.59
42 INT345303 MMP15 Positive_regulation of MMP13 1 1 0.00 1.18 0.58
43 INT356315 Crh Regulation of Cea 1 1 0.16 0.08 0.58
44 INT350699 Binding of Casp8 and Stat3 1 1 0.04 1.81 0.58
45 INT350716 Binding of CD58 and Casp8 1 1 0.03 1.81 0.58
46 INT356311 Crh Regulation of Gabrg1 1 1 0.08 0.08 0.57
47 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 1 0.01 0.05 0.57
48 INT345302 MMP15 Positive_regulation of MMP2 1 1 0.06 1.17 0.57
49 INT149473 Avp Positive_regulation of Localization of Pomc 4 1 0.48 2.64 0.56
50 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 1 0.19 0.37 0.56
51 INT112025 Binding of Hand1 and Il10 2 1 0.15 0.56 0.55
52 INT355881 Il17a Regulation of Gene_expression of Hand1 1 1 0.18 1.51 0.54
53 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 1 0.00 0 0.54
54 INT355878 Il17a Regulation of Eae1 1 1 0.06 1.52 0.54
55 INT355880 Il17a Regulation of Abi3 1 1 0.00 1.52 0.54
56 INT353978 Lmx1b Regulation of Gene_expression of Pet1 1 2 0.31 0.21 0.53
57 INT356351 Binding of CALM1 and TNC 1 1 0.02 0 0.52
58 INT345308 Binding of ABCA1 and TIMP2 1 1 0.00 0.21 0.52
59 INT205030 Crh Positive_regulation of Crhr1 2 1 0.54 1.33 0.51
60 INT345306 Binding of MMP14 and TIMP2 1 1 0.04 0.21 0.48
61 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 1 0.02 0.21 0.48
62 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 1 0.02 1.01 0.48
63 INT338426 Binding of Hand1 and Hand2 2 1 0.06 2 0.46
64 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 1 0.08 0.15 0.46
65 INT340291 Ea1 Regulation of Gene_expression of Ins1 1 1 0.03 0.62 0.46
66 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 1 0.03 1.25 0.46
67 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 1 0.05 1.24 0.45
68 INT354395 TNFSF12 Regulation of Gene_expression of IL18 1 5 0.47 0.79 0.45
69 INT345305 MMP14 Positive_regulation of MMP13 1 1 0.00 0.33 0.45
70 INT345304 MMP14 Positive_regulation of MMP2 1 1 0.08 0.2 0.45
71 INT353631 Oas1a Positive_regulation of Klkb1 1 1 0.00 0 0.44
72 INT339648 Binding of IL23A and Il23a 1 1 0.04 0.13 0.44
73 INT340292 Ea1 Positive_regulation of Ins1 1 1 0.04 0.6 0.43
74 INT345288 AGT Positive_regulation of Localization of CCL2 1 2 0.01 1.5 0.43
75 INT345291 AGT Positive_regulation of CCL2 1 2 0.01 1.39 0.43
76 INT353730 Binding of FCGR2A and FCGR3A 1 1 0.33 0.5 0.41
77 INT350693 Mir326 Positive_regulation of Regulation of thd 1 1 0.00 1.32 0.41
78 INT349289 Binding of SPATA19 and SFTPA1 1 1 0.03 1.2 0.4
79 INT340301 Ea1 Positive_regulation of Gene_expression of ACOX1 1 1 0.01 0.72 0.4
80 INT350698 Mir326 Regulation of Ets1 1 1 0.01 1.27 0.4
81 INT349290 Binding of HLA-B and SPATA19 1 1 0.00 1.25 0.4
82 INT340297 Ea1 Positive_regulation of Negative_regulation of Peg10 1 1 0.00 0 0.39
83 INT356330 ORF61 Regulation of ORF61 Regulation of Crh 1 1 0.00 0.1 0.38
84 INT354062 Avp Regulation of Lyz2 1 1 0.00 0.12 0.38
85 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 1 0.03 0.59 0.38
86 INT356319 ORF61 Regulation of Crh 1 1 0.00 0.1 0.38
87 INT353391 Binding of DRD4 and GRB2 1 1 0.37 0.62 0.37
88 INT353392 Binding of DRD4 and NCK1 1 1 0.37 0.62 0.37
89 INT353390 Binding of DRD4 and SRC 1 1 0.25 0.62 0.37
90 INT353669 Binding of SNRNP70 and CD209 1 4 0.04 6.08 0.35
91 INT352547 Binding of CFTR and DMD 1 1 0.01 1.42 0.35
92 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 2 0.17 2.18 0.34
93 INT346915 Il12a Positive_regulation of Positive_regulation of IFN1@ 1 1 0.20 1.26 0.34
94 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 1 0.03 1.46 0.33
95 INT356323 Binding of ac and Crhr1 1 1 0.01 0 0.32
96 INT356312 Binding of ac and ORF61 1 1 0.00 0 0.32
97 INT336021 EBM Regulation of Regulation of CALM1 1 1 0.18 0 0.32
98 INT313915 Binding of Il12a and Il23a 2 1 0.16 0.44 0.31
99 INT355984 PDC Positive_regulation of Gene_expression of IL17A 1 1 0.06 1.57 0.31
100 INT339645 Binding of Cdk5r1 and Ebi3 1 1 0.01 0.78 0.31
101 INT355979 Negative_regulation of PDC Positive_regulation of Gene_expression of IL17A 1 1 0.06 1.57 0.31
102 INT345421 IFNA1 Positive_regulation of Eif2ak2 2 1 0.03 1.25 0.3
103 INT354821 Nos2 Positive_regulation of Eif2ak2 1 1 0.06 0.64 0.3
104 INT340177 Binding of Oxt and Avpr1a 6 1 0.15 2.24 0.29
105 INT288911 AGT Positive_regulation of CYBB 3 2 0.07 2.96 0.28
106 INT353632 Binding of Shbdp1 and Kncn 1 2 0.05 0 0.28
107 INT333246 Binding of Cxcr4 and Cxcl12 3 1 0.34 0.99 0.27
108 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 1 0.22 0.8 0.26
109 INT356114 Prkca Positive_regulation of Binding of App and Tg 1 1 0.02 0.12 0.26
110 INT356094 Binding of App and Tg 1 1 0.08 0.12 0.26
111 INT353979 Ddc Positive_regulation of Pet1 1 1 0.49 0 0.26
112 INT355982 Binding of HLA-DQA2 and DCPS 1 1 0.00 1.33 0.26
113 INT350835 Binding of SELS and Sels 1 1 0.16 1.24 0.26
114 INT354394 TNFSF12 Regulation of Localization of UNK 1 1 0.21 0 0.25
115 INT355983 CSF2 Regulation of Gene_expression of DCPS 1 1 0.02 0.84 0.25
116 INT354393 NCR1 Regulation of Localization of UNK 1 1 0.17 0 0.25
117 INT198926 Binding of Apbb1 and Lrp1 5 2 0.12 2.18 0.24
118 INT340295 Nrf1 Regulation of Ppargc1a 1 1 0.25 0 0.24
119 INT346912 Il6 Positive_regulation of Gene_expression of Il4 1 1 0.07 0.62 0.24
120 INT356098 Prkca Regulation of Prkaca 1 1 0.01 0.11 0.24
121 INT353981 Gene_expression of Pet1 Positive_regulation of Lmx1b 1 1 0.53 0 0.23
122 INT355981 IFNAR2 Positive_regulation of IDO1 1 1 0.01 1.13 0.23
123 INT355985 IDO1 Positive_regulation of Gene_expression of DCPS 1 1 0.02 1.21 0.23
124 INT354544 Avp Positive_regulation of ADCY1 1 2 0.24 2.23 0.22
125 INT339644 Il27 Regulation of Cd4 1 1 0.03 0.26 0.22
126 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 1 0.17 1.32 0.22
127 INT355877 Binding of Hand1 and Il4 1 1 0.14 0.25 0.22
128 INT356089 Positive_regulation of Binding of Tg and Rab11a 1 1 0.00 0.07 0.21
129 INT356099 Binding of Tg and Rab11a 1 1 0.00 0.07 0.21
130 INT354519 Cacna1c Regulation of Mri1 1 1 0.00 1.15 0.21
131 INT339647 Binding of IFN1@ and Carg1 1 1 0.01 0.75 0.2
132 INT352518 Binding of FAT1 and Adipoq 1 2 0.01 2.79 0.2
133 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 1 0.07 0.5 0.2
134 INT336379 TIMP1 Negative_regulation of FADS1 1 1 0.01 0.52 0.2
135 INT340179 Binding of Oxt and Oxtr 10 2 0.31 2.53 0.19
136 INT256629 Binding of Ptch1 and Shh 7 2 0.42 4.22 0.19
137 INT126944 Binding of PKD2 and Pkd1 2 1 0.08 2.09 0.19
138 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 1 0.04 1.51 0.19
139 INT355363 PTHLH Positive_regulation of Tnfsf11 1 1 0.04 1.47 0.19
140 INT355365 CSF1 Positive_regulation of Tnfsf11 1 1 0.03 1.49 0.19
141 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 1 0.02 1.5 0.19
142 INT355305 Use1 Positive_regulation of Gene_expression of Clec2i 1 2 0.01 3 0.18
143 INT350718 Mir106b Regulation of TGFB1 1 1 0.00 0.42 0.18
144 INT350603 MIR25 Regulation of TGFB1 1 1 0.01 0.42 0.18
145 INT355504 ANGPT2 Positive_regulation of CYBB 1 1 0.01 0.81 0.18
146 INT355304 Use1 Positive_regulation of Clec2i 1 2 0.01 3 0.18
147 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 2 0.35 1.56 0.18
148 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 1 0.03 0.21 0.18
149 INT355307 Use1 Positive_regulation of Gene_expression of Clec5a 1 2 0.02 2.97 0.17
150 INT354400 IL18 Regulation of Gene_expression of TNFSF12 1 3 0.35 0.55 0.17
151 INT355303 Use1 Positive_regulation of Clec5a 1 2 0.02 2.97 0.17
152 INT350717 MIR219-1 Negative_regulation of Zfp238 1 1 0.01 0.4 0.16
153 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 1 0.07 0.57 0.16
154 INT354819 Binding of Cpox and Ptgs2 1 1 0.02 0.45 0.16
155 INT340299 Ea1 Regulation of Ppargc1a 1 1 0.03 0.41 0.16
156 INT350719 MIR219-1 Negative_regulation of Foxj3 1 1 0.01 0.4 0.15
157 INT354823 IFNA1 Positive_regulation of Racgap1 1 1 0.00 1.4 0.15
158 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 1 0.00 0.4 0.15
159 INT350723 MIR219-1 Negative_regulation of Sox6 1 1 0.01 0.4 0.15
160 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 1 0.03 0.15 0.14
161 INT355867 Binding of Afp and HCC 1 1 0.01 2.25 0.14
162 INT355408 Ins1 Regulation of Dbi 1 1 0.07 0.58 0.14
163 INT139849 Binding of App and Bace1 7 1 0.41 0.85 0.13
164 INT354888 Amy1 Regulation of Il10 1 1 0.02 1.41 0.13
165 INT354398 Binding of TNF and TNFSF12 1 1 0.16 0.64 0.13
166 INT354403 IL18 Regulation of TNFSF12 1 2 0.35 0.11 0.13
167 INT354885 Amy1 Regulation of Gene_expression of Il10 1 1 0.03 1.41 0.13
168 INT342309 Apaf1 Positive_regulation of Casp9 1 1 0.02 1.1 0.13
169 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 1 0.17 0.33 0.13
170 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 1 0.08 1.25 0.13
171 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 2 0.09 2.3 0.13
172 INT354065 Pomc Regulation of Cort 1 3 0.07 1.69 0.12
173 INT345289 CRS Regulation of REN 1 1 0.03 1.02 0.12
174 INT355330 Regulation of Gtf3a Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 1 0.00 0.9 0.12
175 INT352501 PRKAB1 Positive_regulation of INS 1 1 0.04 1.36 0.12
176 INT345290 AGT Positive_regulation of NOX1 1 1 0.00 1.11 0.12
177 INT284309 Tlr4 Positive_regulation of Mir155 3 1 0.18 0.51 0.11
178 INT350164 Binding of DURS1 and ELOVL1 1 1 0.00 1.47 0.11
179 INT352497 AGT Positive_regulation of Binding of CRS and 1 1 0.14 0.87 0.11
180 INT350163 Regulation of Binding of DURS1 and ELOVL1 1 1 0.00 1.48 0.11
181 INT354073 Oxt Positive_regulation of Localization of Avp 1 1 0.18 0.37 0.11
182 INT355579 VEGFA Positive_regulation of Gene_expression of IL8 1 1 0.04 1.22 0.1
183 INT352500 Binding of FAT1 and INS 1 1 0.01 1.38 0.1
184 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 1 0.05 0.79 0.1
185 INT355590 VEGFA Positive_regulation of Gene_expression of CCL2 1 1 0.07 1.35 0.1
186 INT355578 VEGFA Positive_regulation of Positive_regulation of IL8 1 1 0.03 1.42 0.1
187 INT350820 INS Regulation of SELS 1 1 0.13 1.11 0.1
188 INT354070 Avpr1b Positive_regulation of Localization of Avp 1 1 0.43 0.06 0.1
189 INT354401 TNFSF12 Regulation of IL18 1 1 0.47 0 0.1
190 INT355581 VEGFA Positive_regulation of CCR4 1 1 0.00 1.36 0.1
191 INT352555 DKK1 Positive_regulation of Wnt2 1 1 0.01 0.25 0.1
192 INT350695 Mir101a Positive_regulation of Protein_catabolism of Icos 1 1 0.05 0.8 0.1
193 INT354077 Avpr1b Positive_regulation of Localization of Gcg 1 1 0.12 0.05 0.1
194 INT355585 VEGFA Positive_regulation of Positive_regulation of CCL2 1 1 0.07 1.35 0.1
195 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 1 0.06 1.35 0.09
196 INT355580 VEGFA Positive_regulation of ICAM1 1 1 0.09 1.39 0.09
197 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 1 0.02 0.17 0.09
198 INT356112 Binding of App and Apba1 1 3 0.24 0.29 0.09
199 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 2 0.23 1.2 0.09
200 INT354753 Ren Regulation of Agt 1 2 0.14 0.98 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in 2011. They are ordered first by their pain relevance and then by number of times they were reported in 2011. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 2011 Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 38 3152 0.78 2515.62 929.82
2 INT7114 Positive_regulation of Ltp 15 1192 0.62 290.76 755.77
3 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
4 INT9238 Gene_expression of IL6 5 1575 0.78 1135.66 424.22
5 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
6 INT76660 Gene_expression of Trpv1 8 691 0.78 329.46 386.42
7 INT18357 Gene_expression of TRPV1 1 825 0.78 307.11 382.81
8 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
9 INT439 Localization of Gnrh1 3 976 0.81 100.96 363.25
10 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
11 INT16260 Gene_expression of Bdnf 9 671 0.78 283.44 339.1
12 INT5235 Negative_regulation of TNF 5 924 0.59 772.91 331.98
13 INT5059 Positive_regulation of TNF 3 1050 0.70 896.51 322.81
14 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
15 INT5680 Gene_expression of Ngf 5 530 0.78 264.29 310.56
16 INT63932 Positive_regulation of Ephb1 2 537 0.70 259.67 296.14
17 INT5379 Gene_expression of Fos 4 656 0.78 255.5 292.54
18 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
19 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
20 INT6852 Localization of TNF 6 883 0.81 705.95 270.84
21 INT10832 Gene_expression of IL8 5 1050 0.78 698.72 270
22 INT9659 Gene_expression of Il6 19 991 0.78 715.11 265.57
23 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
24 INT68684 Gene_expression of VEGFA 13 2371 0.78 1742.52 259.2
25 INT87687 Positive_regulation of Trpv1 12 409 0.70 210.24 257.59
26 INT16868 Gene_expression of Il6 5 807 0.78 499.48 256.57
27 INT11377 Positive_regulation of Ngf 7 331 0.70 206.5 238
28 INT1562 Localization of Crh 2 499 0.81 126.74 236.68
29 INT626 Localization of CALCA 2 289 0.81 125.39 221.15
30 INT6481 Binding of TNF 7 624 0.48 510.2 214.82
31 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
32 INT6482 Positive_regulation of Gene_expression of TNF 6 659 0.70 569.88 210
33 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
34 INT48955 Gene_expression of Nos2 22 753 0.78 403.87 208.08
35 INT6488 Gene_expression of Tnf 5 484 0.78 339.61 191.58
36 INT63934 Phosphorylation of Ephb1 1 377 0.82 150.52 188.66
37 INT6354 Localization of Gabrg1 17 321 0.74 41.41 186.74
38 INT94952 Positive_regulation of Mapk14 2 305 0.70 197.83 186.61
39 INT24326 Gene_expression of Ngf 5 346 0.78 218.67 184.71
40 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
41 INT49441 Negative_regulation of Cpox 5 494 0.59 303.22 177.46
42 INT7506 Negative_regulation of Ltp 12 267 0.46 91.01 176.8
43 INT19472 Gene_expression of Il1 9 554 0.76 419.75 175.35
44 INT15516 Gene_expression of Crp 4 711 0.77 615.33 173.09
45 INT867 Gene_expression of IFNA1 10 930 0.78 594.85 168.03
46 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
47 INT55879 Gene_expression of CCL2 6 421 0.78 240.74 166.02
48 INT1114 Localization of Ins1 9 748 0.80 192.95 165.48
49 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
50 INT66280 Gene_expression of Nos2 7 534 0.78 330.78 157.07
51 INT2640 Gene_expression of Pomc 7 424 0.78 120.72 155.37
52 INT120811 Gene_expression of Gopc 10 1174 0.59 428.49 150.55
53 INT15515 Positive_regulation of Crp 8 700 0.70 604.24 150.15
54 INT7628 Gene_expression of Ltp 7 273 0.77 70.21 147.87
55 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
56 INT9852 Positive_regulation of Gpt 3 563 0.70 364.64 146.82
57 INT812 Localization of INS 13 1026 0.81 515.6 145.31
58 INT60694 Gene_expression of Il10 21 567 0.78 369.48 143.69
59 INT9660 Regulation of TNF 4 363 0.62 312.94 139.99
60 INT14843 Gene_expression of Gabrg1 4 301 0.77 62.63 139.16
61 INT48895 Gene_expression of Il10 2 333 0.78 221.2 138.52
62 INT2867 Gene_expression of CALCA 6 247 0.78 78.78 138.47
63 INT5061 Negative_regulation of Mme 17 306 0.59 51.97 136.9
64 INT48953 Positive_regulation of Nos2 7 486 0.70 239.85 131.87
65 INT5497 Positive_regulation of Crh 2 299 0.70 125.54 131.14
66 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
67 INT49439 Gene_expression of Cpox 22 508 0.73 326.97 130.17
68 INT64161 Positive_regulation of Prkca 3 213 0.70 85.06 129.91
69 INT115386 Gene_expression of Ppara 2 779 0.77 549.99 128.36
70 INT5842 Gene_expression of Gfap 2 372 0.78 153.71 127.71
71 INT1878 Binding of HLA-B 1 440 0.48 321.16 127.36
72 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
73 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
74 INT4259 Positive_regulation of Npr1 1 262 0.70 49.37 123.11
75 INT7533 Gene_expression of Tlr4 2 720 0.78 343.22 121.57
76 INT14151 Gene_expression of Casp3 3 311 0.78 140.26 120.68
77 INT8243 Positive_regulation of Il6 24 451 0.70 358.24 119.28
78 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 21 1138 0.72 311.58 119.18
79 INT17612 Gene_expression of CRP 6 676 0.78 580.61 119.03
80 INT5010 Gene_expression of Calca 3 197 0.78 85.76 118.75
81 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
82 INT12339 Localization of IL8 3 437 0.81 251.87 117.39
83 INT92669 Gene_expression of Bdnf 3 309 0.78 178.26 116.68
84 INT1438 Localization of Pomc 29 360 0.81 101.26 116.47
85 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
86 INT20374 Gene_expression of Il4 9 515 0.76 306.15 114.12
87 INT16253 Positive_regulation of Gene_expression of Bdnf 1 196 0.70 92.67 113.01
88 INT118381 Gene_expression of Il17a 17 405 0.76 306.97 112.06
89 INT7362 Gene_expression of Sst 1 185 0.78 41.73 111.37
90 INT48923 Gene_expression of Ephb1 3 211 0.77 106.23 109.9
91 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
92 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
93 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
94 INT4936 Localization of Tacr1 1 125 0.80 35.7 107.7
95 INT3038 Gene_expression of INS 34 1583 0.78 1174.16 107.01
96 INT9012 Localization of Vip 2 283 0.81 31.71 106.16
97 INT12082 Localization of IL6 2 365 0.81 241.78 105.78
98 INT49171 Gene_expression of Nos1 2 241 0.78 140.7 104.76
99 INT69440 Gene_expression of ROS1 13 752 0.78 477.64 103.83
100 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
101 INT90091 Gene_expression of GOPC 4 967 0.67 366.22 103.6
102 INT10272 Gene_expression of Il1b 3 194 0.78 121.02 103.03
103 INT10838 Positive_regulation of IL8 1 381 0.70 295.51 101.62
104 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
105 INT97701 Phosphorylation of Mapk14 3 191 0.82 115.33 100.46
106 INT65500 Gene_expression of App 28 605 0.78 429.94 98.31
107 INT7944 Positive_regulation of Fos 2 193 0.70 60.69 98.31
108 INT4860 Positive_regulation of CALCA 5 148 0.00 73.35 97.61
109 INT56130 Gene_expression of MC1R 2 259 0.78 62.7 97.55
110 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
111 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
112 INT203 Positive_regulation of Pomc 5 257 0.70 90.56 92.84
113 INT94953 Negative_regulation of Mapk14 1 156 0.59 104.77 91.51
114 INT77435 Positive_regulation of Nos2 2 343 0.70 208.49 91.43
115 INT86024 Gene_expression of PPARA 2 736 0.78 497.93 91.14
116 INT214 Localization of AVP 5 370 0.81 208.51 91.09
117 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
118 INT48767 Negative_regulation of NOS1 6 312 0.59 154.25 90.32
119 INT71789 Positive_regulation of MAPK1 2 396 0.70 234.44 89.27
120 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
121 INT64158 Negative_regulation of Prkca 1 121 0.59 29.8 88.66
122 INT48408 Gene_expression of ICAM1 2 494 0.78 340.08 88.6
123 INT1635 Gene_expression of Vip 12 245 0.78 53.36 88.13
124 INT7180 Negative_regulation of Trib3 2 180 0.51 68.48 88.01
125 INT15898 Positive_regulation of Prkaca 3 199 0.70 50.89 87.54
126 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
127 INT1472 Positive_regulation of Ins1 9 349 0.69 146.2 86.36
128 INT21793 Positive_regulation of Ngf 1 154 0.70 94.78 85.27
129 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
130 INT82448 Gene_expression of S100a8 9 246 0.77 236.72 84.02
131 INT84546 Positive_regulation of Ppara 4 481 0.70 334.21 83.45
132 INT75999 Gene_expression of BDNF 2 344 0.78 114.19 83.12
133 INT16254 Positive_regulation of Gene_expression of Ngf 1 144 0.70 80.61 82.08
134 INT48406 Gene_expression of Icam1 2 277 0.78 238.28 81.71
135 INT68682 Positive_regulation of VEGFA 1 640 0.70 454.14 81.65
136 INT56291 Gene_expression of Ros1 7 503 0.63 274.12 81.5
137 INT148 Positive_regulation of Gnrhr 3 182 0.70 47.44 79.64
138 INT99070 Gene_expression of Mapk14 3 147 0.78 103.99 79.59
139 INT64636 Positive_regulation of Gene_expression of Nos2 12 242 0.70 147.52 79.53
140 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
141 INT3214 Localization of Ins1 20 527 0.80 196.9 79.26
142 INT2431 Positive_regulation of Mpo 5 275 0.70 211.99 78.47
143 INT13036 Positive_regulation of Positive_regulation of Ltp 2 105 0.51 23.71 77.66
144 INT17546 Negative_regulation of Ngf 5 135 0.59 60.28 77.19
145 INT60691 Gene_expression of Il12a 19 331 0.78 208.03 75.96
146 INT3657 Gene_expression of Ins1 11 514 0.78 321.69 75.76
147 INT25363 Negative_regulation of Trpv1 4 144 0.59 64.78 75.7
148 INT16654 Gene_expression of Insrr 1 138 0.46 58.96 75.68
149 INT98621 Regulation of Trpv1 7 121 0.62 79.24 75.23
150 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
151 INT1724 Negative_regulation of ACE 15 437 0.59 315.64 74.48
152 INT48244 Gene_expression of Il4 2 172 0.76 132.38 73.42
153 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
154 INT3034 Localization of Ngf 1 126 0.81 50.81 72.84
155 INT39565 Gene_expression of Ptger2 1 424 0.75 229.28 72.68
156 INT1080 Negative_regulation of Ache 2 343 0.59 108.51 72.4
157 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
158 INT12720 Positive_regulation of Il1 4 246 0.70 195.97 72.05
159 INT14049 Positive_regulation of GRIN1 1 102 0.70 48.31 71.06
160 INT10837 Positive_regulation of Gene_expression of IL8 2 294 0.70 190.08 70.34
161 INT5843 Positive_regulation of Gfap 3 184 0.70 108.2 70.21
162 INT171145 Positive_regulation of Fig4 1 274 0.59 93.55 69.81
163 INT79494 Positive_regulation of Gene_expression of VEGFA 2 577 0.70 442.94 69.73
164 INT170332 Gene_expression of IFN1@ 9 477 0.75 275.21 69.65
165 INT6849 Localization of IL1B 2 229 0.81 112.56 69.63
166 INT13276 Regulation of Ltp 1 107 0.53 30.78 69.13
167 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
168 INT7534 Gene_expression of Ifng 1 193 0.78 111.02 68.6
169 INT9484 Gene_expression of Jun 1 175 0.78 34.89 68.54
170 INT1988 Positive_regulation of Localization of Ins1 4 254 0.69 59.25 68.37
171 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
172 INT19511 Localization of Il6 1 212 0.81 118.17 67.67
173 INT8388 Positive_regulation of Vip 1 142 0.70 39.72 67.61
174 INT102546 Gene_expression of Ccl2 5 197 0.78 192.8 67.41
175 INT5374 Gene_expression of Esr1 4 412 0.77 263.89 67.34
176 INT65733 Positive_regulation of Cnr1 2 125 0.70 40.27 67.33
177 INT462 Regulation of Pomc 3 157 0.62 41.67 67.27
178 INT9489 Gene_expression of SFTPA1 10 112 0.66 55.38 66.45
179 INT4960 Positive_regulation of CSF2 3 285 0.70 256.73 65.73
180 INT1425 Gene_expression of Rbm39 1 143 0.58 51.32 65.44
181 INT11807 Gene_expression of Il2 3 266 0.78 112 64.97
182 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
183 INT11937 Localization of Il6 7 228 0.81 139.83 64.39
184 INT822 Gene_expression of ESR1 1 529 0.78 302.16 63.64
185 INT9657 Positive_regulation of Gene_expression of Il6 5 237 0.70 180.45 63.6
186 INT96622 Localization of Trpv1 3 110 0.81 59.82 63.25
187 INT65730 Gene_expression of Cnr2 1 129 0.78 60.15 63.1
188 INT6894 Gene_expression of CNR1 1 168 0.78 74.07 62.84
189 INT46 Localization of Ren 1 233 0.81 46.15 62.44
190 INT1951 Positive_regulation of Tlr4 6 345 0.70 176.99 62.42
191 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
192 INT1437 Negative_regulation of Pomc 3 132 0.59 35.22 60.97
193 INT11318 Gene_expression of Gtf3a 7 274 0.52 183.82 60.89
194 INT5058 Positive_regulation of IFNA1 6 356 0.70 245.75 60.52
195 INT2761 Regulation of Gabrg1 3 119 0.61 18.8 60.52
196 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
197 INT17564 Gene_expression of Gpt 2 322 0.75 208.51 60.36
198 INT103924 Positive_regulation of Akt1 2 359 0.69 158.94 60.34
199 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
200 INT546 Binding of ALB 1 311 0.48 85.98 60.14
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