D:Alagille Syndrome

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Disease Term
Synonyms AGS, Ahd, Alagille Syndromes, ALAGILLE WATSON SYNDROME, Arteriohepatic Dysplasia, Arteriohepatic Dysplasia Disorder, Arteriohepatic Dysplasias, Aws, Cardiovertebral Syndrome, CHOLESTASIS WITH PERIPHERAL PULMONARY STENOSIS, Ductular Hypoplasia
Documents 191
Hot Single Events 200
Hot Interactions 15

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alagille Syndrome. They are ordered first by their relevance to Alagille Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227218 Binding of JAG1 and CD8A 1 0.05 0.5 0 100.00
2 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0 99.40
3 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 97.66
4 INT141257 Binding of S100A8 and VCL 1 0.36 0.97 0.09 97.00
5 INT227250 Rtl1 Positive_regulation of CD8A 1 0.20 0.4 0 96.56
6 INT130288 POMC Regulation of Gene_expression of VTCN1 1 0.01 0.1 0.59 95.28
7 INT130287 POMC Regulation of Localization of IL10 1 0.12 0.1 0.59 95.28
8 INT152049 Scd1 Negative_regulation of Trav6-3 1 0.00 0.19 0 89.84
9 INT235077 Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.07 0.53 0 87.92
10 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 84.16
11 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 84.16
12 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 84.16
13 INT238004 Positive_regulation of Binding of Cxcr3 and Cxcl11 1 0.30 1.86 0.51 84.16
14 INT106724 ALAD Regulation of IFI27 1 0.17 0.21 0 81.88
15 INT106725 ALAD Regulation of CIB1 1 0.10 0.21 0 81.88
16 INT141256 S100A8 Positive_regulation of VCL 1 0.50 0.99 0.06 74.72
17 INT141258 S100A8 Negative_regulation of VCL 1 0.43 0.99 0.06 74.72
18 INT335239 Binding of HLA-DOA and PMEL 1 0.04 0.68 0 73.56
19 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 71.04
20 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04 71.04
21 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04 71.04
22 INT130286 MC1R Positive_regulation of Localization of IL10 1 0.24 0.07 0.79 69.60
23 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19 68.24
24 INT71642 Binding of HLA-A and PMEL 2 0.20 1.05 0.26 66.68
25 INT179872 Binding of HGF and MET 7 0.09 4.69 0.07 64.72
26 INT352503 POMT1 Negative_regulation of FAT1 1 0.00 0.73 0 63.76
27 INT145150 Positive_regulation of Binding of EGFR and JUN 1 0.24 0.11 0 57.44
28 INT145149 Binding of EGFR and JUN 1 0.16 0.11 0 57.44
29 INT145148 Positive_regulation of Binding of EGFR and FOS 1 0.50 0.05 0 53.96
30 INT145151 Binding of EGFR and FOS 1 0.48 0.05 0 53.96
31 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0 30.92
32 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0 24.56
33 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 23.72
34 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0 20.00
35 INT350113 GNRHR Negative_regulation of Localization of PLOD1 1 0.01 1.06 0 20.00
36 INT350115 GNRH1 Negative_regulation of Localization of PLOD1 1 0.04 0.99 0 18.72
37 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0 18.72
38 INT350119 Positive_regulation of GNRH1 Positive_regulation of PLOD1 1 0.04 0.86 0.03 15.84
39 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03 15.84
40 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 15.44
41 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 15.00
42 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 15.00
43 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01 5.00
44 INT245347 Binding of Penk and Vta1 1 0.05 0.14 1.53 5.00
45 INT245349 Binding of Abat and Gpr156 1 0.02 0.26 1 5.00
46 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8 5.00
47 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3 5.00
48 INT316713 Binding of Ddx41 and Pain1 1 0.00 0.94 0.28 5.00
49 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23 5.00
50 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21 5.00
51 INT238000 Cxcl10 Positive_regulation of Cd4 1 0.21 0.91 0.21 5.00
52 INT238006 Cxcl10 Positive_regulation of Gene_expression of Cd28 1 0.24 0.91 0.21 5.00
53 INT238002 Cxcl10 Positive_regulation of Positive_regulation of Cd4 1 0.21 0.91 0.21 5.00
54 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2 5.00
55 INT238010 Binding of Cxcr3 and Hand1 1 0.12 1.55 0.19 5.00
56 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19 5.00
57 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
58 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15 5.00
59 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14 5.00
60 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
61 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
62 INT352501 PRKAB1 Positive_regulation of INS 1 0.04 1.36 0.12 5.00
63 INT238007 Binding of Cxcr3 and Saa 1 0.14 0.95 0.11 5.00
64 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1 5.00
65 INT145153 JUN Positive_regulation of EGFR 1 0.24 0.94 0.09 5.00
66 INT145154 Positive_regulation of JUN Positive_regulation of EGFR 1 0.24 0.95 0.09 5.00
67 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
68 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
69 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
70 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 5.00
71 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07 5.00
72 INT212442 HGF Positive_regulation of MET 2 0.21 1.25 0.04 5.00
73 INT329102 Binding of CD4 and HLA-DQA2 2 0.04 0.92 0.04 5.00
74 INT238008 Myd88 Regulation of Hand1 1 0.03 0.82 0.04 5.00
75 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03 5.00
76 INT238003 Aif1 Regulation of IgG 1 0.00 0.21 0.03 5.00
77 INT225898 Positive_regulation of RAC1 Positive_regulation of PAK1 1 0.01 0.08 0 5.00
78 INT183248 LPA Positive_regulation of NOS3 1 0.02 0 0 5.00
79 INT313077 Cd180 Regulation of Tlr2 1 0.01 0.09 0 5.00
80 INT329680 BMI1 Negative_regulation of Gene_expression of CDKN2A 1 0.15 1.14 0 5.00
81 INT329676 CBX7 Regulation of Localization of CDKN2A 1 0.51 2.4 0 5.00
82 INT225909 Binding of GRB2 and SOS1 1 0.01 0.11 0 5.00
83 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 5.00
84 INT282879 Binding of MUC5AC and RHCE 1 0.00 0.36 0 5.00
85 INT235075 Ptger2 Positive_regulation of Positive_regulation of Nos2 1 0.00 0.43 0 5.00
86 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0 5.00
87 INT225889 Binding of MET and SHC1 1 0.01 0 0 5.00
88 INT313073 Cd180 Regulation of Tlr4 1 0.02 0.09 0 5.00
89 INT335240 Binding of CD8A and PMEL 1 0.28 0.81 0 5.00
90 INT225887 HGF Positive_regulation of ATF2 1 0.01 0 0 5.00
91 INT225905 Binding of GRB2 and SHC1 1 0.00 0 0 5.00
92 INT313076 Tlr2 Positive_regulation of Gene_expression of Il10 1 0.02 0.14 0 5.00
93 INT225870 Binding of CRKL and Cbl 1 0.00 0 0 5.00
94 INT352516 Binding of POMT1 and Adipoq 1 0.01 0.4 0 5.00
95 INT225906 Binding of GAB1 and GRB2 1 0.01 0.27 0 5.00
96 INT273886 Binding of Dll1 and Trip12 1 0.34 0.1 0 5.00
97 INT225908 Binding of RAC1 and IQGAP1 1 0.00 0.09 0 5.00
98 INT225890 Binding of RAC1 and STAT3 1 0.01 0 0 5.00
99 INT225873 Ilk Positive_regulation of AKT1 1 0.00 0.07 0 5.00
100 INT225903 Binding of GAB1 and PIK3CG 1 0.01 0.13 0 5.00
101 INT225896 HGF Positive_regulation of STAT3 1 0.01 0 0 5.00
102 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0 5.00
103 INT282880 MMP14 Regulation of MUC1 1 0.02 0.17 0 5.00
104 INT225902 Binding of CRKL and GAB1 1 0.01 0.1 0 5.00
105 INT232079 Regulation of Binding of CTBS and TF 1 0.00 0.25 0 5.00
106 INT225874 Positive_regulation of ras Positive_regulation of RAF1 1 0.00 0 0 5.00
107 INT313080 ST2 Regulation of Tlr2 1 0.02 0.09 0 5.00
108 INT313079 SIGIRR Regulation of Tlr2 1 0.18 0.09 0 5.00
109 INT282881 MUC1 Positive_regulation of Gene_expression of MMP14 1 0.04 0.17 0 5.00
110 INT313075 Lgals3 Regulation of Tlr4 1 0.01 0.09 0 5.00
111 INT273885 Binding of Mul1 and Cul2 1 0.06 0 0 5.00
112 INT225871 RAF1 Positive_regulation of Mdk 1 0.00 0 0 5.00
113 INT313081 SIGIRR Regulation of Tlr4 1 0.41 0.09 0 5.00
114 INT225895 Binding of CRK and GAB1 1 0.01 0.1 0 5.00
115 INT329677 CDKN2A Regulation of CBX7 1 0.31 2.23 0 5.00
116 INT225897 PDPK1 Positive_regulation of AKT1 1 0.01 0.07 0 5.00
117 INT225891 DOCK1 Positive_regulation of RAC1 1 0.01 0 0 5.00
118 INT225872 Binding of CRK and Cbl 1 0.00 0 0 5.00
119 INT232078 Binding of CTBS and TF 1 0.00 0.49 0 5.00
120 INT225875 ras Positive_regulation of RAF1 1 0.00 0 0 5.00
121 INT335241 Binding of GZMA and HLA-DOA 1 0.00 0.13 0 5.00
122 INT225894 Binding of MET and PIK3CG 1 0.00 0.13 0 5.00
123 INT225893 Binding of CRKL and DOCK1 1 0.01 0 0 5.00
124 INT313078 ST2 Regulation of Tlr4 1 0.03 0.09 0 5.00
125 INT282882 Binding of MUC1 and MUC5AC 1 0.15 0.56 0 5.00
126 INT329679 CBX7 Regulation of CDKN2A 1 0.31 4.18 0 5.00
127 INT313074 Binding of Bnip3 and Map1lc3a 1 0.01 0.26 0 5.00
128 INT225900 Binding of GAB1 and MET 1 0.00 0.26 0 5.00
129 INT225899 Binding of DOCK1 and RAC1 1 0.01 0 0 5.00
130 INT225907 Binding of CRK and DOCK1 1 0.01 0 0 5.00
131 INT225888 AKT1 Positive_regulation of PAK1 1 0.01 0.08 0 5.00
132 INT335242 Binding of PMEL and CD160 1 0.36 0.85 0 5.00
133 INT225904 Binding of GAB1 and PIK3CA 1 0.07 0.06 0 5.00
134 INT225901 Binding of GRB2 and MET 1 0.00 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alagille Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Alagille Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52 100.00
2 INT39997 Negative_regulation of Gla 8 0.59 6.38 1.51 100.00
3 INT151400 Binding of JAG1 14 0.37 7.96 0.39 100.00
4 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5 100.00
5 INT151401 Localization of JAG1 4 0.65 1.88 0.58 100.00
6 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 100.00
7 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63 100.00
8 INT74781 Regulation of JAG1 6 0.39 2.75 0.63 100.00
9 INT39999 Gene_expression of Gla 7 0.59 3.27 0.69 100.00
10 INT219231 Positive_regulation of Gene_expression of JAG1 1 0.40 1.18 0.05 100.00
11 INT39998 Negative_regulation of Gene_expression of Gla 1 0.34 0.92 0.17 100.00
12 INT28757 Negative_regulation of Gpsm1 1 0.38 0.99 0.38 100.00
13 INT28758 Regulation of Gpsm1 1 0.24 0.97 0.4 100.00
14 INT146794 Positive_regulation of Gla 2 0.50 1.21 0 100.00
15 INT235063 Positive_regulation of Gene_expression of Gla 2 0.04 0.81 0.39 100.00
16 INT125449 Regulation of Gene_expression of CLDN4 2 0.60 1.07 0.61 100.00
17 INT296418 Binding of PPIH 1 0.02 1.31 0 100.00
18 INT212895 Binding of Gpsm1 1 0.03 2.13 0.04 100.00
19 INT212894 Gene_expression of Gpsm1 1 0.05 2.11 0.04 100.00
20 INT212888 Positive_regulation of Gpsm1 1 0.04 2.12 0.04 100.00
21 INT212889 Positive_regulation of Gene_expression of Gpsm1 1 0.04 2.12 0.04 100.00
22 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0 100.00
23 INT128425 Negative_regulation of TPPP 1 0.07 1.42 0.12 100.00
24 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.92
25 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 99.88
26 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 99.86
27 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47 99.86
28 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.84
29 INT125451 Gene_expression of CLDN4 5 0.78 4.75 2.01 99.84
30 INT55168 Binding of NFKB1 55 0.48 22.94 13.15 99.84
31 INT20627 Regulation of Gene_expression of LDHA 5 0.42 4.07 0.92 99.84
32 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 99.84
33 INT125448 Positive_regulation of Gene_expression of CLDN4 3 0.70 1.01 1.02 99.84
34 INT87193 Gene_expression of Tnfrsf1b 30 0.58 29.4 9.22 99.84
35 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 99.84
36 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17 99.84
37 INT142162 Binding of IL10 30 0.37 21.9 4.84 99.80
38 INT625 Localization of PGC 35 0.80 11.33 3.05 99.76
39 INT14 Regulation of LDHA 22 0.57 15.26 2.14 99.56
40 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 99.56
41 INT10324 Positive_regulation of Fam166a 13 0.00 2.23 2.33 99.56
42 INT136632 Negative_regulation of Gene_expression of RMI2 1 0.43 1.89 0.9 99.48
43 INT136633 Gene_expression of RMI2 1 0.60 1.89 0.9 99.48
44 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52 99.48
45 INT104945 Regulation of Gene_expression of DYT10 1 0.60 0.85 0.28 99.48
46 INT104944 Gene_expression of DYT10 1 0.75 0.85 0.28 99.48
47 INT10019 Binding of CD8A 57 0.36 31.49 10.08 99.44
48 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 99.40
49 INT273867 Binding of Jag1 18 0.45 3.14 0.25 99.40
50 INT171433 Gene_expression of AIC 7 0.59 3.06 1.11 99.36
51 INT36892 Positive_regulation of Trav6-3 57 0.68 12.15 3.8 99.32
52 INT168388 Negative_regulation of Positive_regulation of Casp9 1 0.20 1.43 0.3 99.28
53 INT116143 Positive_regulation of Casp9 32 0.67 30.34 3.04 99.28
54 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 99.22
55 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.20
56 INT93728 Gene_expression of Cd28 8 0.35 7.11 0.59 99.20
57 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.18
58 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 99.18
59 INT86584 Phosphorylation of S100A8 10 0.80 4.99 0.41 99.12
60 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 99.06
61 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 99.00
62 INT113415 Positive_regulation of gp 8 0.28 1.62 2.07 98.88
63 INT147634 Regulation of Cd28 2 0.44 3.23 0.82 98.76
64 INT10916 Positive_regulation of BDNF-AS 39 0.49 25.88 5.28 98.72
65 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55 98.56
66 INT9385 Localization of LDHA 74 0.81 31.67 10.5 98.36
67 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 98.12
68 INT152048 Negative_regulation of Gene_expression of Trav6-3 4 0.57 1.47 0.1 98.12
69 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 98.08
70 INT14159 Negative_regulation of Positive_regulation of Adarb1 8 0.08 2.06 5.14 98.08
71 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 98.08
72 INT257559 Localization of AIC 3 0.69 1.43 0.12 98.06
73 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 98.04
74 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 98.04
75 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 97.92
76 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 97.92
77 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94 97.84
78 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49 97.84
79 INT125450 Negative_regulation of Gene_expression of CLDN4 1 0.43 0.47 0.46 97.56
80 INT73497 Regulation of IL10 33 0.45 22.6 9.19 97.52
81 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42 97.28
82 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 97.28
83 INT81724 Positive_regulation of RPL7AP7 1 0.00 1.26 1.09 97.24
84 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 97.00
85 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63 97.00
86 INT62112 Binding of S100A8 37 0.36 17.18 3.16 97.00
87 INT182031 Gene_expression of Cia1 38 0.24 46.37 19.64 96.92
88 INT187089 Positive_regulation of Gene_expression of Cia1 9 0.14 10 4.11 96.92
89 INT82798 Regulation of MYC 19 0.60 12.06 2.31 96.88
90 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 96.88
91 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 96.72
92 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22 96.72
93 INT125447 Positive_regulation of CLDN4 14 0.70 4.71 4.45 96.60
94 INT64208 Gene_expression of Rtl1 18 0.75 7.51 6.16 96.60
95 INT207384 Gene_expression of Pgia1 3 0.14 18.55 6.87 96.60
96 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 96.56
97 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 96.40
98 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 96.40
99 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 96.40
100 INT67399 Negative_regulation of Transcription of Il12a 2 0.03 2.63 1.05 96.40
101 INT67400 Negative_regulation of Transcription of Il4 1 0.04 1.71 0.29 96.40
102 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72 96.28
103 INT127698 Localization of AIFM1 15 0.79 13.45 4.74 96.24
104 INT127695 Positive_regulation of Localization of AIFM1 5 0.64 4.29 1.87 96.24
105 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55 96.20
106 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33 96.08
107 INT204021 Transcription of Gsk3b 8 0.57 2.75 0.23 96.00
108 INT158 Localization of Prl 2431 0.81 378.96 952.2 95.92
109 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 95.92
110 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 95.88
111 INT84731 Positive_regulation of Gene_expression of Rtl1 3 0.49 1.96 0.09 95.88
112 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 95.76
113 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 95.64
114 INT104941 Negative_regulation of Prkcb 4 0.39 2.94 1.47 95.52
115 INT104940 Gene_expression of Prkcb 2 0.03 0.9 0.58 95.52
116 INT104939 Negative_regulation of Gene_expression of Prkcb 1 0.02 0.86 0.29 95.52
117 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67 95.32
118 INT74423 Localization of IL10 91 0.80 61.6 22.95 95.32
119 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 95.28
120 INT17496 Regulation of Maob 7 0.60 6.49 3.62 95.20
121 INT2396 Regulation of Maoa 25 0.62 6.04 13.27 95.20
122 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12 95.08
123 INT67398 Transcription of Il12a 3 0.26 3.16 1.49 95.08
124 INT73476 Transcription of MYC 18 0.69 12.14 2.13 95.00
125 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32 95.00
126 INT10323 Gene_expression of Fam166a 48 0.00 11.76 15.68 95.00
127 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66 95.00
128 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 94.92
129 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75 94.88
130 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 94.80
131 INT130289 Gene_expression of VTCN1 3 0.45 1.61 0.81 94.56
132 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 94.48
133 INT67397 Transcription of Il4 15 0.54 11.36 6.06 94.48
134 INT25172 Positive_regulation of Localization of PGC 9 0.68 3.01 1.02 94.16
135 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12 94.12
136 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4 93.92
137 INT3364 Binding of SGCG 87 0.47 31.93 17.24 93.92
138 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 93.92
139 INT76959 Binding of Ctnnb1 2 0.34 0.69 0 93.92
140 INT52107 Transcription of IL8 63 0.72 41.66 16.06 93.64
141 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28 93.60
142 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 93.36
143 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 93.28
144 INT134657 Localization of Akt1 37 0.68 11.58 4.62 93.28
145 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55 93.24
146 INT235069 Localization of Cdh1 9 0.74 3.81 0.71 92.80
147 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 92.72
148 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75 92.68
149 INT82795 Binding of MYC 16 0.47 6.1 0.9 92.60
150 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95 92.60
151 INT152046 Positive_regulation of Positive_regulation of Trav6-3 9 0.45 3.47 0.55 92.60
152 INT125445 Positive_regulation of Positive_regulation of CLDN4 1 0.70 0.52 0.53 92.56
153 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 91.96
154 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46 91.96
155 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 91.96
156 INT117470 Positive_regulation of Positive_regulation of ISYNA1 7 0.51 6.87 1.94 91.96
157 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3 91.96
158 INT6481 Binding of TNF 624 0.48 510.2 214.82 91.92
159 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 91.40
160 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35 91.40
161 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 91.28
162 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 91.28
163 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 91.04
164 INT9835 Binding of AICDA 29 0.47 6.76 0.66 90.84
165 INT178280 Regulation of PAX7 4 0.44 1.34 0.21 90.40
166 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 90.00
167 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74 90.00
168 INT145156 Regulation of Regulation of EGFR 1 0.24 1.31 0.03 90.00
169 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8 89.96
170 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 89.56
171 INT73508 Negative_regulation of Gene_expression of ISYNA1 32 0.51 19.67 7.57 89.40
172 INT211968 Localization of Best1 11 0.40 9.33 0.38 89.36
173 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22 89.04
174 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39 89.00
175 INT6852 Localization of TNF 883 0.81 705.95 270.84 88.64
176 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 88.56
177 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 88.52
178 INT87287 Phosphorylation of CDCP1 20 0.04 5.62 2.43 88.48
179 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 88.32
180 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 88.24
181 INT94059 Positive_regulation of Transcription of ISYNA1 5 0.26 3.82 0.85 88.20
182 INT153146 Positive_regulation of AIFM1 1 0.68 1.85 0.66 87.92
183 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 87.80
184 INT128424 Transcription of STAT1 5 0.37 3.28 0.9 87.80
185 INT4806 Localization of TPSAB1 29 0.80 5.05 10.52 87.64
186 INT30238 Positive_regulation of Anpep 14 0.66 2.77 3.38 87.60
187 INT94060 Transcription of ISYNA1 18 0.43 6.7 2.18 87.36
188 INT59465 Negative_regulation of ISYNA1 41 0.49 21.9 9.46 87.32
189 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7 87.28
190 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 87.24
191 INT11388 Positive_regulation of PMEL 11 0.67 5.9 2.09 87.20
192 INT47752 Regulation of Fam166a 6 0.00 1.93 1.82 87.04
193 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29 87.04
194 INT88600 Positive_regulation of Binding of NFKB1 9 0.59 2.1 0.88 86.88
195 INT56149 Localization of CD8A 56 0.74 30.41 5.75 86.16
196 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 86.12
197 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 86.08
198 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 85.96
199 INT70222 Binding of POMT1 22 0.37 11.73 1.69 85.68
200 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 85.56
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