D:Alcoholic Cardiomyopathy

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Disease Term
Synonyms None
Documents 18
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Cardiomyopathy. They are ordered first by their relevance to Alcoholic Cardiomyopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 60.20
2 INT292871 Binding of Fas and Tg(MMTV-Notch4)3Rnc 1 0.05 1.25 0.03 60.00
3 INT292872 Binding of Fasl and Tg(MMTV-Notch4)3Rnc 1 0.05 1.25 0.03 59.84
4 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21 49.04
5 INT317399 Binding of Acc and Amp1 1 0.05 0.55 0.11 49.04
6 INT317393 Binding of Car2 and Ide 1 0.03 0.3 0 21.88
7 INT317396 Binding of Car2 and Prkag1 1 0.07 0.31 0 21.88
8 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 5.00
9 INT317392 Negative_regulation of Binding of Stk11 and Amp1 1 0.05 0.34 0.1 5.00
10 INT317403 Negative_regulation of Binding of Prkag1 and Amp1 1 0.03 0.35 0.1 5.00
11 INT317401 Binding of Prkag1 and Amp1 1 0.03 0.35 0.1 5.00
12 INT317402 Positive_regulation of Amp1 Positive_regulation of Prkag1 1 0.03 0.27 0.09 5.00
13 INT317390 Amp1 Positive_regulation of Phosphorylation of Prkag1 1 0.03 0.22 0.07 5.00
14 INT317398 Amp1 Positive_regulation of Phosphorylation of Stk11 1 0.05 0.22 0.07 5.00
15 INT317391 Amp1 Positive_regulation of Stk11 1 0.05 0.22 0.07 5.00
16 INT317387 Amp1 Positive_regulation of Prkag1 1 0.04 0.34 0.07 5.00
17 INT317389 Binding of Prkag1 and Stk11 1 0.16 0.2 0.06 5.00
18 INT317397 Negative_regulation of Binding of Prkag1 and Stk11 1 0.19 0.2 0.06 5.00
19 INT317388 Stk11 Regulation of Positive_regulation of Prkag1 1 0.23 0.11 0.03 5.00
20 INT317400 Acc Positive_regulation of Prkag1 1 0.29 0.06 0.03 5.00
21 INT317395 Gopc Regulation of Gene_expression of Car2 2 0.10 0 0.03 5.00
22 INT317404 Acc Positive_regulation of Stk11 1 0.41 0.06 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Cardiomyopathy. They are ordered first by their pain relevance and then by number of times they were reported in Alcoholic Cardiomyopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2 99.28
2 INT275338 Positive_regulation of Gene_expression of Gfm1 5 0.03 3.14 0.16 99.28
3 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34 97.92
4 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 91.64
5 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 91.64
6 INT72316 Regulation of Amp1 5 0.07 1.19 0.39 90.36
7 INT6757 Localization of MANEA 4 0.54 1.77 0.25 87.32
8 INT151588 Phosphorylation of Prkag1 48 0.73 15.62 1.38 87.20
9 INT5489 Localization of CA2 172 0.80 39.46 33.56 86.16
10 INT116143 Positive_regulation of Casp9 32 0.67 30.34 3.04 82.32
11 INT151583 Regulation of Prkag1 11 0.21 3.68 0.85 82.20
12 INT226111 Gene_expression of Prkag1 24 0.45 9.76 1.05 81.64
13 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08 80.52
14 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 79.76
15 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 78.16
16 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 77.76
17 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 77.76
18 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95 77.76
19 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 76.80
20 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22 76.80
21 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 76.40
22 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36 73.12
23 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97 72.48
24 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 72.16
25 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 68.84
26 INT141187 Positive_regulation of Gene_expression of Casp9 3 0.49 4.2 1 68.52
27 INT292851 Negative_regulation of Tnfrsf21 1 0.07 1.34 0.03 68.20
28 INT141183 Gene_expression of Casp9 9 0.75 11.96 2.46 67.72
29 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 65.56
30 INT3535 Regulation of CA2 61 0.32 16.48 10.8 62.64
31 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 61.04
32 INT88278 Binding of Kit 33 0.37 24.45 4.13 60.56
33 INT137503 Positive_regulation of Positive_regulation of Casp9 6 0.67 4.66 0.74 59.16
34 INT153077 Positive_regulation of Gene_expression of Nppa 9 0.40 5.07 0.13 58.76
35 INT135042 Gene_expression of Tg(MMTV-Notch4)3Rnc 9 0.15 5.17 1.13 57.08
36 INT73432 Gene_expression of Nppa 32 0.59 21.04 1.39 55.36
37 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27 54.32
38 INT292852 Positive_regulation of Binding of Gfm1 2 0.03 2.56 0.17 53.88
39 INT189093 Binding of Atp8a1 10 0.47 2.6 0.11 53.60
40 INT15990 Binding of Gfm1 10 0.31 8.53 1.37 53.56
41 INT17302 Positive_regulation of Atp8a1 7 0.49 2.56 0.78 53.24
42 INT141037 Positive_regulation of Aifm1 3 0.45 3.32 1.38 52.40
43 INT292860 Positive_regulation of Siva1 1 0.12 1.2 0 52.40
44 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 50.08
45 INT7134 Localization of KNG1 127 0.79 65.73 67.97 49.48
46 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11 49.04
47 INT317359 Positive_regulation of Amp1 9 0.08 1.93 0.73 49.04
48 INT236581 Regulation of Gene_expression of Slc2a4 3 0.36 0.5 0.09 49.04
49 INT191145 Positive_regulation of Gene_expression of Atp8a1 14 0.67 5.24 1.02 47.64
50 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94 47.32
51 INT317357 Binding of Prkag1 2 0.25 3.23 0.3 45.52
52 INT151581 Positive_regulation of Phosphorylation of Prkag1 6 0.61 1.97 0.11 45.52
53 INT292858 Localization of Casp8 2 0.27 1.68 0.03 45.40
54 INT116195 Localization of Casp9 4 0.15 4.33 0.18 44.68
55 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 44.16
56 INT158341 Negative_regulation of Gene_expression of ALDH2 3 0.58 0.98 0.53 43.16
57 INT158339 Gene_expression of ALDH2 18 0.78 4.48 1.65 42.60
58 INT310378 Regulation of Gene_expression of ALDH2 1 0.27 0.47 0.15 42.60
59 INT137679 Localization of Gfm1 18 0.08 9.58 3.24 41.96
60 INT317361 Negative_regulation of Gene_expression of Slc2a4 1 0.40 0.15 0 39.60
61 INT305245 Negative_regulation of Gene_expression of Prkag1 2 0.21 0.95 0 39.60
62 INT269103 Gene_expression of AOX1 2 0.26 1.97 0.46 36.48
63 INT137634 Localization of Aifm1 17 0.80 11.8 3.45 36.32
64 INT151584 Negative_regulation of Prkag1 10 0.38 1.72 0.67 35.28
65 INT158340 Negative_regulation of ALDH2 13 0.58 2.76 1.64 35.20
66 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 31.20
67 INT151574 Gene_expression of Aifm1 5 0.62 3.63 2.34 28.64
68 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83 23.52
69 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6 23.20
70 INT253108 Phosphorylation of Stk11 4 0.65 2.13 0.52 23.20
71 INT317356 Phosphorylation of Acc 1 0.80 0.74 0.23 23.20
72 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78 22.48
73 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 21.84
74 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02 21.24
75 INT286615 Phosphorylation of Ide 7 0.31 5.22 0.7 20.16
76 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06 15.68
77 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 15.40
78 INT106022 Negative_regulation of GSTP1 5 0.59 2.12 0.55 15.12
79 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 14.92
80 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 13.08
81 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 13.08
82 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57 13.08
83 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3 13.08
84 INT1158 Regulation of Agt 106 0.61 29.4 30.29 12.16
85 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 12.16
86 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62 10.00
87 INT292853 Positive_regulation of Binding of Aox1 1 0.13 2.27 0.22 9.12
88 INT118152 Binding of Aox1 2 0.09 1.6 1.62 8.24
89 INT135077 Binding of GSTP1 11 0.48 7.03 1.8 7.52
90 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
91 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 5.00
92 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
93 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
94 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 5.00
95 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
96 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 5.00
97 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 5.00
98 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
99 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
100 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 5.00
101 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
102 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
103 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77 5.00
104 INT17962 Regulation of Car2 124 0.41 33.98 22.71 5.00
105 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
106 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 5.00
107 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 5.00
108 INT10173 Binding of Tnf 45 0.48 35.6 14.32 5.00
109 INT122037 Regulation of Ppara 93 0.62 56.28 12.89 5.00
110 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18 5.00
111 INT113317 Regulation of Cnr2 17 0.52 10.27 10.68 5.00
112 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 5.00
113 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 5.00
114 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97 5.00
115 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84 5.00
116 INT1490 Regulation of Prkacb 7 0.21 0.5 4.52 5.00
117 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4 5.00
118 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21 5.00
119 INT105974 Positive_regulation of PRKAB1 43 0.67 23.47 4.16 5.00
120 INT163358 Positive_regulation of Ppargc1a 24 0.67 12.47 4.05 5.00
121 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25 5.00
122 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 5.00
123 INT181818 Gene_expression of Ppargc1a 50 0.78 24.33 2.71 5.00
124 INT194019 Gene_expression of Acc 4 0.65 3.18 2.54 5.00
125 INT191974 Regulation of Ide 16 0.38 9.54 2.52 5.00
126 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13 5.00
127 INT28188 Regulation of CYP2E1 11 0.62 0.48 2.03 5.00
128 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83 5.00
129 INT114061 Regulation of Gene_expression of Insr 4 0.27 2.03 1.56 5.00
130 INT19342 Regulation of Insr 12 0.24 6.11 1.54 5.00
131 INT12429 Negative_regulation of Spdya 5 0.20 1.07 1.49 5.00
132 INT191970 Positive_regulation of Ide 29 0.51 12.94 1.4 5.00
133 INT30023 Regulation of PAF1 7 0.17 1.84 1.38 5.00
134 INT181823 Positive_regulation of Gene_expression of Ppargc1a 20 0.67 6.45 1.33 5.00
135 INT241608 Positive_regulation of Acc 2 0.67 1.2 1.16 5.00
136 INT132667 Regulation of Transcription of NOS1 1 0.30 2.58 0.95 5.00
137 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78 5.00
138 INT73095 Negative_regulation of PAF1 6 0.57 1.48 0.78 5.00
139 INT191978 Positive_regulation of Gene_expression of Ide 16 0.63 6.8 0.65 5.00
140 INT291769 Positive_regulation of Gene_expression of ALDH2 2 0.69 2.48 0.65 5.00
141 INT183877 Gene_expression of PAF1 13 0.75 5.33 0.48 5.00
142 INT226109 Localization of Prkag1 3 0.43 1.89 0.44 5.00
143 INT135043 Regulation of Gene_expression of Tg(MMTV-Notch4)3Rnc 2 0.10 0.28 0.43 5.00
144 INT212415 Positive_regulation of Positive_regulation of PRKAB1 4 0.36 2.63 0.37 5.00
145 INT183880 Negative_regulation of Gene_expression of PAF1 2 0.42 1.3 0.35 5.00
146 INT310379 Negative_regulation of FOXO3 2 0.42 1.28 0.32 5.00
147 INT287030 Positive_regulation of Tg(MMTV-Notch4)3Rnc 2 0.05 0.71 0.21 5.00
148 INT196759 Negative_regulation of Negative_regulation of Ppp2ca 2 0.30 0.17 0.2 5.00
149 INT151580 Negative_regulation of Phosphorylation of Prkag1 7 0.33 3.45 0.18 5.00
150 INT253110 Positive_regulation of Positive_regulation of Prkag1 5 0.28 0.78 0.14 5.00
151 INT258412 Localization of PAF1 1 0.48 1.87 0.13 5.00
152 INT317355 Positive_regulation of Positive_regulation of Amp1 2 0.06 0.39 0.12 5.00
153 INT183882 Positive_regulation of Gene_expression of PAF1 4 0.49 2.77 0.11 5.00
154 INT292859 Positive_regulation of Card9 1 0.11 0.75 0.1 5.00
155 INT317362 Positive_regulation of Regulation of Amp1 1 0.06 0.09 0.09 5.00
156 INT317351 Gene_expression of Amp1 1 0.08 0.09 0.09 5.00
157 INT317360 Positive_regulation of Gene_expression of Amp1 1 0.06 0.09 0.09 5.00
158 INT183888 Positive_regulation of PAF1 6 0.49 1.62 0.08 5.00
159 INT292854 Regulation of Tg(MMTV-Notch4)3Rnc 1 0.07 0.9 0.08 5.00
160 INT317364 Phosphorylation of Amp1 1 0.07 0.22 0.07 5.00
161 INT253107 Regulation of Stk11 2 0.33 0.3 0.07 5.00
162 INT292861 Regulation of Binding of Gfm1 1 0.03 0.06 0.06 5.00
163 INT317363 Regulation of Acc 1 0.26 0.07 0.04 5.00
164 INT305234 Regulation of Phosphorylation of Prkag1 2 0.30 1.07 0.04 5.00
165 INT317354 Regulation of Phosphorylation of Stk11 1 0.36 0.12 0.03 5.00
166 INT253104 Gene_expression of Stk11 2 0.53 0.07 0.03 5.00
167 INT317366 Regulation of Phosphorylation of Acc 1 0.26 0 0 5.00
168 INT308848 Regulation of Phosphorylation of Gopc 4 0.28 0.48 0 5.00
169 INT258413 Regulation of Gene_expression of PAF1 1 0.29 0.42 0 5.00
170 INT317353 Positive_regulation of Gene_expression of Tg(MMTV-Notch4)3Rnc 1 0.04 0 0 5.00
171 INT317352 Positive_regulation of Phosphorylation of Stk11 1 0.32 0 0 5.00
172 INT317358 Positive_regulation of Positive_regulation of Acc 1 0.49 0 0 5.00
173 INT292857 Regulation of Nppa 3 0.30 1.56 0 5.00
174 INT317365 Localization of Amp1 1 0.09 0 0 5.00
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