D:Alcoholic Cardiomyopathy

Disease Term Synonyms None Documents 18 Hot Single Events 13 Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Cardiomyopathy. They are ordered first by their relevance to Alcoholic Cardiomyopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT292873	Binding of Fas and Fasl	5	0.26	15.74	0.49	60.20
2	INT292871	Binding of Fas and Tg(MMTV-Notch4)3Rnc	1	0.05	1.25	0.03	60.00
3	INT292872	Binding of Fasl and Tg(MMTV-Notch4)3Rnc	1	0.05	1.25	0.03	59.84
4	INT317394	Binding of Stk11 and Amp1	1	0.04	0.89	0.21	49.04
5	INT317399	Binding of Acc and Amp1	1	0.05	0.55	0.11	49.04
6	INT317393	Binding of Car2 and Ide	1	0.03	0.3	0	21.88
7	INT317396	Binding of Car2 and Prkag1	1	0.07	0.31	0	21.88
8	INT350363	Gatm Negative_regulation of NOS1	1	0.00	0.31	0.17	5.00
9	INT317392	Negative_regulation of Binding of Stk11 and Amp1	1	0.05	0.34	0.1	5.00
10	INT317403	Negative_regulation of Binding of Prkag1 and Amp1	1	0.03	0.35	0.1	5.00
11	INT317401	Binding of Prkag1 and Amp1	1	0.03	0.35	0.1	5.00
12	INT317402	Positive_regulation of Amp1 Positive_regulation of Prkag1	1	0.03	0.27	0.09	5.00
13	INT317390	Amp1 Positive_regulation of Phosphorylation of Prkag1	1	0.03	0.22	0.07	5.00
14	INT317398	Amp1 Positive_regulation of Phosphorylation of Stk11	1	0.05	0.22	0.07	5.00
15	INT317391	Amp1 Positive_regulation of Stk11	1	0.05	0.22	0.07	5.00
16	INT317387	Amp1 Positive_regulation of Prkag1	1	0.04	0.34	0.07	5.00
17	INT317389	Binding of Prkag1 and Stk11	1	0.16	0.2	0.06	5.00
18	INT317397	Negative_regulation of Binding of Prkag1 and Stk11	1	0.19	0.2	0.06	5.00
19	INT317388	Stk11 Regulation of Positive_regulation of Prkag1	1	0.23	0.11	0.03	5.00
20	INT317400	Acc Positive_regulation of Prkag1	1	0.29	0.06	0.03	5.00
21	INT317395	Gopc Regulation of Gene_expression of Car2	2	0.10	0	0.03	5.00
22	INT317404	Acc Positive_regulation of Stk11	1	0.41	0.06	0.03	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Cardiomyopathy. They are ordered first by their pain relevance and then by number of times they were reported in Alcoholic Cardiomyopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT19393	Gene_expression of Gfm1	31	0.51	18.9	3.2	99.28
2	INT275338	Positive_regulation of Gene_expression of Gfm1	5	0.03	3.14	0.16	99.28
3	INT139008	Positive_regulation of Gfm1	21	0.35	7.79	2.34	97.92
4	INT72703	Gene_expression of Ide	79	0.70	45.04	4.47	91.64
5	INT115386	Gene_expression of Ppara	779	0.77	549.99	128.36	91.64
6	INT72316	Regulation of Amp1	5	0.07	1.19	0.39	90.36
7	INT6757	Localization of MANEA	4	0.54	1.77	0.25	87.32
8	INT151588	Phosphorylation of Prkag1	48	0.73	15.62	1.38	87.20
9	INT5489	Localization of CA2	172	0.80	39.46	33.56	86.16
10	INT116143	Positive_regulation of Casp9	32	0.67	30.34	3.04	82.32
11	INT151583	Regulation of Prkag1	11	0.21	3.68	0.85	82.20
12	INT226111	Gene_expression of Prkag1	24	0.45	9.76	1.05	81.64
13	INT90272	Gene_expression of Ppp2ca	18	0.68	4.69	2.08	80.52
14	INT11793	Negative_regulation of CA2	78	0.57	19.63	12.35	79.76
15	INT77306	Negative_regulation of Gene_expression of Bcl2	46	0.58	38.05	7.71	78.16
16	INT77307	Gene_expression of Bcl2	399	0.77	319.77	38	77.76
17	INT109511	Gene_expression of Bax	133	0.78	113.22	14.36	77.76
18	INT175507	Regulation of Gene_expression of Bax	13	0.50	10.91	0.95	77.76
19	INT78694	Positive_regulation of Gene_expression of Casp3	46	0.66	18.64	19.62	76.80
20	INT105103	Regulation of Gene_expression of Casp3	11	0.39	3.15	9.22	76.80
21	INT31116	Gene_expression of Casp3	192	0.78	78.21	57.43	76.40
22	INT108249	Negative_regulation of Prdx2	3	0.32	1.85	1.36	73.12
23	INT70323	Negative_regulation of Gene_expression of CA2	13	0.41	6.55	0.97	72.48
24	INT23533	Gene_expression of CA2	110	0.75	30.81	19.4	72.16
25	INT115385	Negative_regulation of Ppara	154	0.58	129.05	27.58	68.84
26	INT141187	Positive_regulation of Gene_expression of Casp9	3	0.49	4.2	1	68.52
27	INT292851	Negative_regulation of Tnfrsf21	1	0.07	1.34	0.03	68.20
28	INT141183	Gene_expression of Casp9	9	0.75	11.96	2.46	67.72
29	INT151586	Positive_regulation of Prkag1	51	0.54	18.7	3.34	65.56
30	INT3535	Regulation of CA2	61	0.32	16.48	10.8	62.64
31	INT6488	Gene_expression of Tnf	484	0.78	339.61	191.58	61.04
32	INT88278	Binding of Kit	33	0.37	24.45	4.13	60.56
33	INT137503	Positive_regulation of Positive_regulation of Casp9	6	0.67	4.66	0.74	59.16
34	INT153077	Positive_regulation of Gene_expression of Nppa	9	0.40	5.07	0.13	58.76
35	INT135042	Gene_expression of Tg(MMTV-Notch4)3Rnc	9	0.15	5.17	1.13	57.08
36	INT73432	Gene_expression of Nppa	32	0.59	21.04	1.39	55.36
37	INT139010	Regulation of Gfm1	16	0.32	5.02	3.27	54.32
38	INT292852	Positive_regulation of Binding of Gfm1	2	0.03	2.56	0.17	53.88
39	INT189093	Binding of Atp8a1	10	0.47	2.6	0.11	53.60
40	INT15990	Binding of Gfm1	10	0.31	8.53	1.37	53.56
41	INT17302	Positive_regulation of Atp8a1	7	0.49	2.56	0.78	53.24
42	INT141037	Positive_regulation of Aifm1	3	0.45	3.32	1.38	52.40
43	INT292860	Positive_regulation of Siva1	1	0.12	1.2	0	52.40
44	INT11480	Positive_regulation of Localization of KNG1	15	0.30	6.39	5.5	50.08
45	INT7134	Localization of KNG1	127	0.79	65.73	67.97	49.48
46	INT55294	Gene_expression of Slc2a4	17	0.70	6.84	1.11	49.04
47	INT317359	Positive_regulation of Amp1	9	0.08	1.93	0.73	49.04
48	INT236581	Regulation of Gene_expression of Slc2a4	3	0.36	0.5	0.09	49.04
49	INT191145	Positive_regulation of Gene_expression of Atp8a1	14	0.67	5.24	1.02	47.64
50	INT170455	Gene_expression of Atp8a1	66	0.75	24.63	3.94	47.32
51	INT317357	Binding of Prkag1	2	0.25	3.23	0.3	45.52
52	INT151581	Positive_regulation of Phosphorylation of Prkag1	6	0.61	1.97	0.11	45.52
53	INT292858	Localization of Casp8	2	0.27	1.68	0.03	45.40
54	INT116195	Localization of Casp9	4	0.15	4.33	0.18	44.68
55	INT120811	Gene_expression of Gopc	1174	0.59	428.49	150.55	44.16
56	INT158341	Negative_regulation of Gene_expression of ALDH2	3	0.58	0.98	0.53	43.16
57	INT158339	Gene_expression of ALDH2	18	0.78	4.48	1.65	42.60
58	INT310378	Regulation of Gene_expression of ALDH2	1	0.27	0.47	0.15	42.60
59	INT137679	Localization of Gfm1	18	0.08	9.58	3.24	41.96
60	INT317361	Negative_regulation of Gene_expression of Slc2a4	1	0.40	0.15	0	39.60
61	INT305245	Negative_regulation of Gene_expression of Prkag1	2	0.21	0.95	0	39.60
62	INT269103	Gene_expression of AOX1	2	0.26	1.97	0.46	36.48
63	INT137634	Localization of Aifm1	17	0.80	11.8	3.45	36.32
64	INT151584	Negative_regulation of Prkag1	10	0.38	1.72	0.67	35.28
65	INT158340	Negative_regulation of ALDH2	13	0.58	2.76	1.64	35.20
66	INT30170	Gene_expression of Car2	330	0.66	77.26	46.76	31.20
67	INT151574	Gene_expression of Aifm1	5	0.62	3.63	2.34	28.64
68	INT110180	Phosphorylation of JUN	23	0.80	11.21	3.83	23.52
69	INT194479	Phosphorylation of Ppara	47	0.81	30.36	6.6	23.20
70	INT253108	Phosphorylation of Stk11	4	0.65	2.13	0.52	23.20
71	INT317356	Phosphorylation of Acc	1	0.80	0.74	0.23	23.20
72	INT106524	Phosphorylation of Jun	23	0.80	15.35	4.78	22.48
73	INT80222	Negative_regulation of Bcl2	82	0.58	69.16	13.18	21.84
74	INT90277	Negative_regulation of Ppp2ca	15	0.41	4.04	4.02	21.24
75	INT286615	Phosphorylation of Ide	7	0.31	5.22	0.7	20.16
76	INT109513	Positive_regulation of Gene_expression of Bax	37	0.67	29.52	5.06	15.68
77	INT53575	Regulation of Gene_expression of Tnf	46	0.62	34.35	20.63	15.40
78	INT106022	Negative_regulation of GSTP1	5	0.59	2.12	0.55	15.12
79	INT6489	Positive_regulation of Gene_expression of Tnf	140	0.70	92.31	67.85	14.92
80	INT390	Positive_regulation of Agt	170	0.70	61.47	36.08	13.08
81	INT6726	Positive_regulation of Edn1	118	0.70	65.96	24.07	13.08
82	INT7153	Positive_regulation of Regulation of Edn1	2	0.35	1.97	0.57	13.08
83	INT4636	Positive_regulation of Regulation of Agt	4	0.50	1.3	0.3	13.08
84	INT1158	Regulation of Agt	106	0.61	29.4	30.29	12.16
85	INT5806	Regulation of Edn1	63	0.62	23.46	13.88	12.16
86	INT296253	Negative_regulation of Gene_expression of Ppp2ca	3	0.41	1.71	0.62	10.00
87	INT292853	Positive_regulation of Binding of Aox1	1	0.13	2.27	0.22	9.12
88	INT118152	Binding of Aox1	2	0.09	1.6	1.62	8.24
89	INT135077	Binding of GSTP1	11	0.48	7.03	1.8	7.52
90	INT5200	Gene_expression of Fos	3083	0.78	894.43	1639.02	5.00
91	INT6056	Negative_regulation of Gene_expression of Fos	601	0.59	193.05	386.84	5.00
92	INT48955	Gene_expression of Nos2	753	0.78	403.87	208.08	5.00
93	INT48953	Positive_regulation of Nos2	486	0.70	239.85	131.87	5.00
94	INT69764	Positive_regulation of Cnr1	126	0.70	67.8	91.49	5.00
95	INT48767	Negative_regulation of NOS1	312	0.59	154.25	90.32	5.00
96	INT74376	Gene_expression of Cnr1	173	0.78	73.43	89.7	5.00
97	INT58400	Negative_regulation of Tnf	182	0.59	129.97	71	5.00
98	INT48952	Negative_regulation of Nos2	204	0.59	101.73	53.15	5.00
99	INT49017	Negative_regulation of Gene_expression of Nos2	169	0.59	80.64	52.67	5.00
100	INT76620	Gene_expression of Cnr2	93	0.78	34.7	50.14	5.00
101	INT17561	Localization of Car2	303	0.79	60.95	44.52	5.00
102	INT69437	Positive_regulation of ROS1	328	0.58	222.83	40.56	5.00
103	INT74377	Regulation of Cnr1	38	0.59	16.93	24.77	5.00
104	INT17962	Regulation of Car2	124	0.41	33.98	22.71	5.00
105	INT86187	Positive_regulation of AKT1	199	0.69	122.13	19.44	5.00
106	INT83198	Positive_regulation of Nos3	78	0.64	35.69	17.71	5.00
107	INT91913	Regulation of GRIN3B	16	0.61	11.48	14.44	5.00
108	INT10173	Binding of Tnf	45	0.48	35.6	14.32	5.00
109	INT122037	Regulation of Ppara	93	0.62	56.28	12.89	5.00
110	INT110988	Gene_expression of Insr	58	0.42	42.12	12.18	5.00
111	INT113317	Regulation of Cnr2	17	0.52	10.27	10.68	5.00
112	INT48908	Transcription of NOS1	27	0.55	13.46	8.39	5.00
113	INT175526	Phosphorylation of Gopc	73	0.53	21.08	7.86	5.00
114	INT114058	Negative_regulation of Gene_expression of Insr	13	0.31	9.23	4.97	5.00
115	INT51392	Negative_regulation of Insr	18	0.27	14.75	4.84	5.00
116	INT1490	Regulation of Prkacb	7	0.21	0.5	4.52	5.00
117	INT76581	Regulation of Negative_regulation of NOS1	14	0.45	7.49	4.4	5.00
118	INT76467	Regulation of Gene_expression of Car2	41	0.37	12.88	4.21	5.00
119	INT105974	Positive_regulation of PRKAB1	43	0.67	23.47	4.16	5.00
120	INT163358	Positive_regulation of Ppargc1a	24	0.67	12.47	4.05	5.00
121	INT196779	Phosphorylation of Ppp2ca	28	0.72	1.86	3.25	5.00
122	INT91890	Positive_regulation of Kit	36	0.50	25.44	3.06	5.00
123	INT181818	Gene_expression of Ppargc1a	50	0.78	24.33	2.71	5.00
124	INT194019	Gene_expression of Acc	4	0.65	3.18	2.54	5.00
125	INT191974	Regulation of Ide	16	0.38	9.54	2.52	5.00
126	INT116194	Gene_expression of Casp8	14	0.75	14.61	2.13	5.00
127	INT28188	Regulation of CYP2E1	11	0.62	0.48	2.03	5.00
128	INT123130	Positive_regulation of Positive_regulation of AKT1	22	0.49	11.77	1.83	5.00
129	INT114061	Regulation of Gene_expression of Insr	4	0.27	2.03	1.56	5.00
130	INT19342	Regulation of Insr	12	0.24	6.11	1.54	5.00
131	INT12429	Negative_regulation of Spdya	5	0.20	1.07	1.49	5.00
132	INT191970	Positive_regulation of Ide	29	0.51	12.94	1.4	5.00
133	INT30023	Regulation of PAF1	7	0.17	1.84	1.38	5.00
134	INT181823	Positive_regulation of Gene_expression of Ppargc1a	20	0.67	6.45	1.33	5.00
135	INT241608	Positive_regulation of Acc	2	0.67	1.2	1.16	5.00
136	INT132667	Regulation of Transcription of NOS1	1	0.30	2.58	0.95	5.00
137	INT136690	Regulation of Negative_regulation of Tnf	5	0.45	3.58	0.78	5.00
138	INT73095	Negative_regulation of PAF1	6	0.57	1.48	0.78	5.00
139	INT191978	Positive_regulation of Gene_expression of Ide	16	0.63	6.8	0.65	5.00
140	INT291769	Positive_regulation of Gene_expression of ALDH2	2	0.69	2.48	0.65	5.00
141	INT183877	Gene_expression of PAF1	13	0.75	5.33	0.48	5.00
142	INT226109	Localization of Prkag1	3	0.43	1.89	0.44	5.00
143	INT135043	Regulation of Gene_expression of Tg(MMTV-Notch4)3Rnc	2	0.10	0.28	0.43	5.00
144	INT212415	Positive_regulation of Positive_regulation of PRKAB1	4	0.36	2.63	0.37	5.00
145	INT183880	Negative_regulation of Gene_expression of PAF1	2	0.42	1.3	0.35	5.00
146	INT310379	Negative_regulation of FOXO3	2	0.42	1.28	0.32	5.00
147	INT287030	Positive_regulation of Tg(MMTV-Notch4)3Rnc	2	0.05	0.71	0.21	5.00
148	INT196759	Negative_regulation of Negative_regulation of Ppp2ca	2	0.30	0.17	0.2	5.00
149	INT151580	Negative_regulation of Phosphorylation of Prkag1	7	0.33	3.45	0.18	5.00
150	INT253110	Positive_regulation of Positive_regulation of Prkag1	5	0.28	0.78	0.14	5.00
151	INT258412	Localization of PAF1	1	0.48	1.87	0.13	5.00
152	INT317355	Positive_regulation of Positive_regulation of Amp1	2	0.06	0.39	0.12	5.00
153	INT183882	Positive_regulation of Gene_expression of PAF1	4	0.49	2.77	0.11	5.00
154	INT292859	Positive_regulation of Card9	1	0.11	0.75	0.1	5.00
155	INT317362	Positive_regulation of Regulation of Amp1	1	0.06	0.09	0.09	5.00
156	INT317351	Gene_expression of Amp1	1	0.08	0.09	0.09	5.00
157	INT317360	Positive_regulation of Gene_expression of Amp1	1	0.06	0.09	0.09	5.00
158	INT183888	Positive_regulation of PAF1	6	0.49	1.62	0.08	5.00
159	INT292854	Regulation of Tg(MMTV-Notch4)3Rnc	1	0.07	0.9	0.08	5.00
160	INT317364	Phosphorylation of Amp1	1	0.07	0.22	0.07	5.00
161	INT253107	Regulation of Stk11	2	0.33	0.3	0.07	5.00
162	INT292861	Regulation of Binding of Gfm1	1	0.03	0.06	0.06	5.00
163	INT317363	Regulation of Acc	1	0.26	0.07	0.04	5.00
164	INT305234	Regulation of Phosphorylation of Prkag1	2	0.30	1.07	0.04	5.00
165	INT317354	Regulation of Phosphorylation of Stk11	1	0.36	0.12	0.03	5.00
166	INT253104	Gene_expression of Stk11	2	0.53	0.07	0.03	5.00
167	INT317366	Regulation of Phosphorylation of Acc	1	0.26	0	0	5.00
168	INT308848	Regulation of Phosphorylation of Gopc	4	0.28	0.48	0	5.00
169	INT258413	Regulation of Gene_expression of PAF1	1	0.29	0.42	0	5.00
170	INT317353	Positive_regulation of Gene_expression of Tg(MMTV-Notch4)3Rnc	1	0.04	0	0	5.00
171	INT317352	Positive_regulation of Phosphorylation of Stk11	1	0.32	0	0	5.00
172	INT317358	Positive_regulation of Positive_regulation of Acc	1	0.49	0	0	5.00
173	INT292857	Regulation of Nppa	3	0.30	1.56	0	5.00
174	INT317365	Localization of Amp1	1	0.09	0	0	5.00