D:Anus Neoplasms

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pChart

Disease Term
Synonyms Anal Cancer, ANAL CANCERS, ANAL NEOPLASM, Anal Neoplasms, Anus Cancer, ANUS CANCERS, Anus Neoplasm, Cancer Anal, Cancer Of Anus, Cancer Of The Anus, Cancers Anal
Documents 55
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Anus Neoplasms. They are ordered first by their relevance to Anus Neoplasms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
2 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
3 INT335259 Binding of GSTM1 and RA1 1 0.11 0.78 0.13 5.00
4 INT326167 Binding of CD4 and Tmed8 1 0.47 0.29 0 5.00
5 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0 5.00
6 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
7 INT352994 IPMK Regulation of VEGFA 1 0.00 0.66 0 5.00
8 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
9 INT315889 Binding of B4GALNT1 and IKBKAP 1 0.00 0.68 0 5.00
10 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Anus Neoplasms. They are ordered first by their pain relevance and then by number of times they were reported in Anus Neoplasms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 98.28
2 INT125829 Binding of VAC14 2 0.31 2.02 0.38 92.32
3 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 87.40
4 INT81796 Binding of AGRP 62 0.36 37.19 5.3 87.00
5 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 86.64
6 INT104524 Localization of FSCN1 3 0.13 1.76 1.75 85.56
7 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 74.96
8 INT216858 Negative_regulation of PID1 4 0.35 6.3 1.11 72.72
9 INT116980 Positive_regulation of CCL20 5 0.70 4.8 1.02 48.56
10 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 48.56
11 INT11154 Binding of EGFR 149 0.48 96.23 6.29 46.64
12 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 46.64
13 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 43.68
14 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 34.76
15 INT161322 Localization of PTEN 9 0.73 5.65 0.57 31.32
16 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 25.08
17 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
18 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
19 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
20 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
21 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
22 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
23 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
24 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
25 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
26 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 5.00
27 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
28 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
29 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
30 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
31 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
32 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
33 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 5.00
34 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
35 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
36 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 5.00
37 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
38 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
39 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
40 INT2491 Regulation of Cea 38 0.61 26.18 10.95 5.00
41 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
42 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 5.00
43 INT91758 Binding of CCR5 28 0.45 20.16 7.07 5.00
44 INT51137 Negative_regulation of GSTM1 39 0.43 14.74 6.5 5.00
45 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 5.00
46 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
47 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
48 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
49 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
50 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 5.00
51 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
52 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 5.00
53 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
54 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
55 INT17182 Binding of Cea 25 0.48 14.98 4.16 5.00
56 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5 5.00
57 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33 5.00
58 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 5.00
59 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
60 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
61 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76 5.00
62 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
63 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
64 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
65 INT248374 Binding of IKBKAP 10 0.42 10.45 1.9 5.00
66 INT65545 Localization of EGFR 35 0.79 20.8 1.88 5.00
67 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
68 INT24863 Negative_regulation of SLC12A2 12 0.44 1.85 1.61 5.00
69 INT62296 Gene_expression of PDXP 8 0.67 6.48 1.44 5.00
70 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34 5.00
71 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 5.00
72 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 5.00
73 INT60060 Positive_regulation of KRAS 17 0.67 11.68 1.21 5.00
74 INT237247 Regulation of Mri1 6 0.27 4.64 1.2 5.00
75 INT106261 Negative_regulation of DPYD 16 0.59 15.02 1.19 5.00
76 INT166261 Localization of SLN 2 0.66 1.23 1.07 5.00
77 INT86834 Positive_regulation of Tg 10 0.69 4.9 1.04 5.00
78 INT58692 Regulation of Gene_expression of CD8A 11 0.42 10.16 1 5.00
79 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
80 INT263912 Positive_regulation of SLN 6 0.39 0.66 0.99 5.00
81 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 5.00
82 INT228875 Positive_regulation of RA1 4 0.29 4.13 0.92 5.00
83 INT104908 Binding of B4GALNT1 7 0.05 4.62 0.82 5.00
84 INT335265 Gene_expression of RA1 4 0.40 5.13 0.79 5.00
85 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75 5.00
86 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 5.00
87 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 5.00
88 INT61910 Binding of Slc3a2 6 0.01 3 0.7 5.00
89 INT246036 Positive_regulation of GRN 3 0.17 2.04 0.69 5.00
90 INT156566 Negative_regulation of TRPV6 2 0.41 0.97 0.68 5.00
91 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
92 INT214707 Gene_expression of Slc2a8 5 0.24 2.76 0.61 5.00
93 INT11225 Positive_regulation of SLC12A2 3 0.45 1.1 0.6 5.00
94 INT88870 Negative_regulation of PDXP 4 0.43 4.64 0.57 5.00
95 INT118436 Positive_regulation of TRPV6 3 0.49 2.19 0.53 5.00
96 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 5.00
97 INT335266 Regulation of RA1 2 0.27 2.57 0.52 5.00
98 INT335263 Localization of RA1 3 0.47 3.04 0.52 5.00
99 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 5.00
100 INT258200 Localization of VAC14 1 0.34 2.28 0.5 5.00
101 INT138676 Localization of ADAM17 4 0.73 4.91 0.5 5.00
102 INT263904 Negative_regulation of Gene_expression of SLN 1 0.14 7.18 0.47 5.00
103 INT207177 Gene_expression of VAC14 4 0.42 3.49 0.46 5.00
104 INT178813 Gene_expression of ARC 9 0.67 10.78 0.43 5.00
105 INT98708 Binding of KRAS 13 0.47 7.47 0.39 5.00
106 INT329299 Binding of RA1 6 0.35 4.52 0.35 5.00
107 INT158766 Localization of GRN 2 0.73 1.59 0.28 5.00
108 INT50948 Gene_expression of SLC12A2 6 0.59 4.55 0.22 5.00
109 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21 5.00
110 INT263884 Gene_expression of Slc2a3 2 0.18 0.86 0.19 5.00
111 INT245298 Negative_regulation of VEGFC 3 0.42 3.66 0.16 5.00
112 INT20214 Localization of Slc3a2 5 0.14 4.91 0.16 5.00
113 INT188757 Positive_regulation of Gene_expression of AGRP 12 0.44 5.86 0.13 5.00
114 INT212170 Localization of CDIPT 4 0.41 1.55 0.13 5.00
115 INT263871 Negative_regulation of Car9 1 0.07 0.54 0.12 5.00
116 INT263908 Positive_regulation of Gene_expression of SLN 1 0.16 1.4 0.12 5.00
117 INT263872 Localization of Adra1d 1 0.01 2.5 0.11 5.00
118 INT178053 Positive_regulation of STIP1 7 0.44 5.09 0.11 5.00
119 INT335264 Binding of OA3 1 0.17 0.64 0.1 5.00
120 INT332577 Negative_regulation of SLN 1 0.35 0.08 0.1 5.00
121 INT335262 Positive_regulation of OA3 1 0.23 0.64 0.08 5.00
122 INT285813 Negative_regulation of ERCC1 13 0.30 2.03 0.08 5.00
123 INT263878 Positive_regulation of Rigs1 1 0.05 2.57 0.07 5.00
124 INT258201 Positive_regulation of Localization of VAC14 1 0.23 1.16 0.06 5.00
125 INT214703 Positive_regulation of Gene_expression of Slc2a8 2 0.09 1.4 0.05 5.00
126 INT306447 Positive_regulation of CCR10 1 0.04 1.17 0.04 5.00
127 INT263879 Positive_regulation of Adra1d 1 0.00 0.47 0.04 5.00
128 INT263873 Positive_regulation of Gene_expression of Rigs1 1 0.05 1.27 0.03 5.00
129 INT263877 Gene_expression of Rigs1 1 0.08 11.58 0.03 5.00
130 INT263911 Localization of TMED7-TICAM2 1 0.01 1.02 0 5.00
131 INT263906 Gene_expression of TMED7-TICAM2 1 0.01 2.8 0 5.00
132 INT315886 Regulation of Positive_regulation of PIK3CA 1 0.10 0.53 0 5.00
133 INT321441 Binding of IGLL5 1 0.00 0.59 0 5.00
134 INT263874 Regulation of Rigs1 1 0.03 1.36 0 5.00
135 INT236621 Regulation of KRAS 7 0.53 6.16 0 5.00
136 INT216857 Positive_regulation of Positive_regulation of STIP1 1 0.09 0.77 0 5.00
137 INT263914 Binding of TMED7-TICAM2 1 0.01 1.56 0 5.00
138 INT315883 Positive_regulation of Positive_regulation of JAK1 1 0.01 0.38 0 5.00
139 INT263910 Regulation of SLN 1 0.15 1.01 0 5.00
140 INT304052 Binding of MSI1 8 0.05 12.19 0 5.00
141 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0 5.00
142 INT203875 Phosphorylation of GSTM1 2 0.81 1.27 0 5.00
143 INT263883 Localization of Rigs1 1 0.08 2.36 0 5.00
144 INT263881 Binding of Rigs1 1 0.04 0.99 0 5.00
145 INT341719 Transcription of FAM49B 1 0.04 1.1 0 5.00
146 INT263876 Negative_regulation of Rigs1 1 0.04 0.98 0 5.00
147 INT326166 Binding of Tmed8 1 0.35 0.29 0 5.00
148 INT315881 Binding of Eltd1 1 0.01 0.61 0 5.00
149 INT341718 Positive_regulation of Transcription of FAM49B 1 0.03 1.1 0 5.00
150 INT263909 Positive_regulation of Gene_expression of TMED7-TICAM2 1 0.01 0.87 0 5.00
151 INT263880 Regulation of Gene_expression of Rigs1 1 0.05 0.48 0 5.00
152 INT263915 Binding of SLN 2 0.12 0.81 0 5.00
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