D:Ascariasis

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Disease Term
Synonyms ASCARIASES, Ascaris Lumbricoides, Roundworm
Documents 178
Hot Single Events 19
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ascariasis. They are ordered first by their relevance to Ascariasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT270568 Binding of UTS2R and STAT6 1 0.04 2 0.05 95.60
2 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 34.00
3 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
4 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15 5.00
5 INT307529 Binding of IK and TRNAC1 1 0.00 0.07 0.12 5.00
6 INT270566 IGHE Regulation of IL4 1 0.21 0.99 0.09 5.00
7 INT270567 IGHE Regulation of IL13RA2 1 0.23 0.99 0.09 5.00
8 INT270569 IGHE Regulation of IL5 1 0.18 1.04 0.09 5.00
9 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05 5.00
10 INT270586 Binding of IGHE and IgG-2a 1 0.16 0.75 0.03 5.00
11 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0 5.00
12 INT304170 Binding of Apaf1 and Positive_regulation of Casp9 1 0.01 0.51 0 5.00
13 INT304175 IL1B Positive_regulation of Gene_expression of Vcam1 1 0.02 0.96 0 5.00
14 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0 5.00
15 INT285291 TNF Positive_regulation of Gene_expression of Vcam1 2 0.10 3.1 0 5.00
16 INT304176 Binding of IL1B and Il13 1 0.00 0.96 0 5.00
17 INT304167 Il4 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.94 0 5.00
18 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0 5.00
19 INT304171 Il13 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.89 0 5.00
20 INT304174 Binding of IL1B and Il4 1 0.00 0.96 0 5.00
21 INT270570 Binding of IGHG3 and FCGR2C 1 0.00 0.22 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ascariasis. They are ordered first by their pain relevance and then by number of times they were reported in Ascariasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT7979 Binding of Nsdhl 6 0.30 3.71 0.4 100.00
2 INT158440 Negative_regulation of Nsdhl 4 0.21 3.22 0.51 100.00
3 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58 100.00
4 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 98.96
5 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 98.40
6 INT147113 Binding of LTF 14 0.29 18.24 0.98 98.16
7 INT15357 Positive_regulation of STH 7 0.49 4.55 1.6 97.80
8 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 95.76
9 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 94.36
10 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 92.40
11 INT103378 Binding of Spink1 24 0.40 15.3 6.19 91.48
12 INT1542 Binding of Prss1 8 0.30 4.25 3.74 91.48
13 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 85.04
14 INT98294 Binding of STAT6 2 0.40 1.63 0.39 84.76
15 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 84.68
16 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 84.16
17 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 83.04
18 INT10303 Regulation of STH 16 0.60 16.14 0.95 82.64
19 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 80.28
20 INT121422 Gene_expression of BIRC3 7 0.75 6.24 0.96 79.48
21 INT44600 Gene_expression of MALT1 6 0.75 6.14 0.42 79.48
22 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 78.16
23 INT311687 Binding of 119L04aR 2 0.01 0.61 0 77.92
24 INT110425 Gene_expression of ITGAE 7 0.58 4.48 0.91 77.64
25 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 73.84
26 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 69.92
27 INT180029 Regulation of rsm1 3 0.02 2.38 0.55 69.84
28 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 65.88
29 INT135273 Negative_regulation of Tcrb 3 0.05 2.71 0.14 65.88
30 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 59.20
31 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 55.20
32 INT140394 Regulation of Dync1h1 7 0.39 2.59 1.25 55.20
33 INT335202 Negative_regulation of 119L04aR 1 0.01 0.38 0 53.36
34 INT85130 Regulation of IL5 14 0.27 8.37 3.55 52.60
35 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 52.32
36 INT156522 Gene_expression of NAPEPLD 11 0.75 4.25 2.87 49.60
37 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 49.12
38 INT171021 Negative_regulation of IL5 18 0.41 14.74 3.39 45.32
39 INT270687 Negative_regulation of Regulation of IL5 2 0.25 0.91 0.07 45.32
40 INT270577 Localization of STAT6 1 0.62 0.51 0.04 42.00
41 INT65500 Gene_expression of App 605 0.78 429.94 98.31 36.16
42 INT59793 Regulation of Gene_expression of STH 2 0.44 0.88 0.51 28.92
43 INT135274 Positive_regulation of RQCD1 2 0.36 1.24 0.08 25.00
44 INT36287 Binding of CD4 96 0.47 58.93 11.88 24.80
45 INT73500 Regulation of IL13 12 0.36 10.37 3.53 18.80
46 INT226435 Regulation of STAT6 4 0.37 2.98 0.34 18.80
47 INT206657 Positive_regulation of NAPEPLD 4 0.07 1.05 0.05 18.12
48 INT206659 Positive_regulation of Positive_regulation of NAPEPLD 1 0.07 0.18 0 18.12
49 INT270574 Gene_expression of IL13RA2 9 0.68 5.46 0.42 11.20
50 INT221711 Negative_regulation of Gene_expression of STH 1 0.06 0.81 0 10.72
51 INT113101 Gene_expression of Ccl11 41 0.76 22.36 5.47 10.64
52 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
53 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
54 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
55 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
56 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
57 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
58 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
59 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
60 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
61 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
62 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
63 INT6437 Binding of YY1 154 0.47 26.3 90.46 5.00
64 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
65 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
66 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
67 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
68 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
69 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
70 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
71 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
72 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
73 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
74 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 5.00
75 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
76 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
77 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
78 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
79 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
80 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
81 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
82 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 5.00
83 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
84 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 5.00
85 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
86 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
87 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 5.00
88 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 5.00
89 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
90 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
91 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
92 INT75929 Gene_expression of IL9 61 0.43 24.71 16.17 5.00
93 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
94 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 5.00
95 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
96 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 5.00
97 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
98 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 5.00
99 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 5.00
100 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
101 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
102 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
103 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 5.00
104 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 5.00
105 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38 5.00
106 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
107 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 5.00
108 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 5.00
109 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
110 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 5.00
111 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 5.00
112 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
113 INT85418 Positive_regulation of Gene_expression of IL9 11 0.38 11.47 9.56 5.00
114 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
115 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 5.00
116 INT3622 Regulation of CTSB 34 0.58 16.08 8.76 5.00
117 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 5.00
118 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
119 INT165036 Gene_expression of S100a9 38 0.77 38.33 7.84 5.00
120 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 5.00
121 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
122 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4 5.00
123 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
124 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 5.00
125 INT12818 Regulation of IgG-2a 9 0.37 3.23 6.07 5.00
126 INT304151 Gene_expression of Siglec5 2 0.74 17.33 6.03 5.00
127 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92 5.00
128 INT132573 Negative_regulation of Gene_expression of TH1L 16 0.42 11.52 5.76 5.00
129 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
130 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 5.00
131 INT26962 Negative_regulation of IgG-2a 12 0.42 6.07 5.31 5.00
132 INT177526 Negative_regulation of Il5 17 0.36 11.13 5.31 5.00
133 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29 5.00
134 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16 5.00
135 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75 5.00
136 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 5.00
137 INT100912 Regulation of Kdm5d 52 0.32 20.39 4.72 5.00
138 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
139 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55 5.00
140 INT18995 Binding of CEL 23 0.47 14.46 4.5 5.00
141 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 5.00
142 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
143 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
144 INT194380 Negative_regulation of Gene_expression of IL5 22 0.42 15.78 4.1 5.00
145 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1 5.00
146 INT123752 Regulation of Bax 19 0.60 16.45 4 5.00
147 INT112692 Localization of Bax 31 0.80 20.97 3.98 5.00
148 INT270686 Gene_expression of Il7r 17 0.71 7.93 3.94 5.00
149 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 5.00
150 INT4464 Localization of CEL 21 0.80 8.09 3.88 5.00
151 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
152 INT70919 Binding of Il4 19 0.36 6.58 3.59 5.00
153 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
154 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 5.00
155 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 5.00
156 INT114276 Gene_expression of Nr4a1 20 0.77 7.71 3.14 5.00
157 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98 5.00
158 INT202577 Localization of DIO2 9 0.56 1.3 2.97 5.00
159 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69 5.00
160 INT122656 Gene_expression of MTNR1A 21 0.75 6.37 2.46 5.00
161 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46 5.00
162 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 5.00
163 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 5.00
164 INT98225 Regulation of Il5 8 0.45 5.07 2.06 5.00
165 INT128058 Regulation of PER1 6 0.43 1.82 1.89 5.00
166 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86 5.00
167 INT20377 Gene_expression of Il3 8 0.65 0.82 1.77 5.00
168 INT94534 Gene_expression of MT2A 8 0.75 11.28 1.76 5.00
169 INT143664 Gene_expression of ST2 9 0.77 5.03 1.73 5.00
170 INT25163 Positive_regulation of Gene_expression of IL2RA 8 0.45 5.37 1.71 5.00
171 INT186269 Binding of Il13 9 0.39 7.7 1.64 5.00
172 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6 5.00
173 INT114279 Positive_regulation of Nr4a1 9 0.59 3.37 1.59 5.00
174 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 5.00
175 INT114270 Gene_expression of Plscr1 6 0.47 1.33 1.49 5.00
176 INT152223 Binding of BEST1 10 0.29 6.67 1.46 5.00
177 INT152308 Binding of Lgals3 13 0.40 6.39 1.44 5.00
178 INT102414 Localization of SM1 2 0.29 0.95 1.43 5.00
179 INT254666 Positive_regulation of Map2k2 37 0.56 23.85 1.35 5.00
180 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3 5.00
181 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3 5.00
182 INT27256 Localization of STH 6 0.70 0.46 1.29 5.00
183 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28 5.00
184 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 5.00
185 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2 5.00
186 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 5.00
187 INT114272 Regulation of Gene_expression of Nr4a1 5 0.45 1.82 1.14 5.00
188 INT183046 Transcription of INS 25 0.70 11.14 1.13 5.00
189 INT154057 Gene_expression of Ear1 14 0.41 9.72 1.12 5.00
190 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 5.00
191 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1 5.00
192 INT73450 Gene_expression of Pilra 7 0.05 2.87 0.97 5.00
193 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 5.00
194 INT123948 Positive_regulation of Plscr1 4 0.42 1.02 0.93 5.00
195 INT183362 Regulation of AQP1 3 0.23 1.49 0.92 5.00
196 INT228727 Transcription of Il5 4 0.27 5.13 0.9 5.00
197 INT124940 Binding of MTNR1A 8 0.36 2.29 0.9 5.00
198 INT160830 Gene_expression of Siglece 6 0.39 2.37 0.85 5.00
199 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82 5.00
200 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 5.00
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